Zheng Fan, Tongtong Fu, Zhoufei Li, Bing Du, Xiaohu Cui, Rui Zhang, Yanling Feng, Hanqing Zhao, Guanhua Xue, Jinghua Cui, Chao Yan, Lin Gan, Junxia Feng, Ziying Xu, Zihui Yu, Ziyan Tian, Zanbo Ding, Jinfeng Chen, Yujie Chen, Jing Yuan
Klebsiella pneumoniae is a well-known human nosocomial pathogen with an arsenal of virulence factors, including capsular polysaccharides (CPS), fimbriae, flagella, and lipopolysaccharides (LPS). Our previous study found that alcohol acted as an essential virulence factor for high-alcohol-producing K. pneumoniae (HiAlc Kpn ). Integration host factor (IHF) is a nucleoid-associated protein that functions as a global virulence regulator in Escherichia coli . However, the regulatory role of IHF in K. pneumoniae remains unknown...
September 21, 2023: Microbiology Spectrum