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Interpretation bias

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https://www.readbyqxmd.com/read/28328574/the-long-term-reliability-of-static-and-dynamic-quantitative-sensory-testing-in-healthy-individuals
#1
Anna Marcuzzi, Paul J Wrigley, Catherine M Dean, Roger Adams, Julia M Hush
Quantitative sensory tests (QST) have been increasingly used to investigate alterations in somatosensory function in a wide range of painful conditions. The interpretation of these findings is based on the assumption that the measures are stable and reproducible. To date, reliability of QST has been investigated for short test-retest intervals. The aim of this study was to investigate the long-term reliability of a multimodal QST assessment in healthy people, with testing conducted on three occasions over 4-months...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28323851/the-effect-of-excluding-juveniles-on-apparent-adult-olive-baboons-papio-anubis-social-networks
#2
Piotr Fedurek, Julia Lehmann
In recent years there has been much interest in investigating the social structure of group living animals using social network analysis. Many studies so far have focused on the social networks of adults, often excluding younger, immature group members. This potentially may lead to a biased view of group social structure as multiple recent studies have shown that younger group members can significantly contribute to group structure. As proof of the concept, we address this issue by investigating social network structure with and without juveniles in wild olive baboons (Papio anubis) at Gashaka Gumti National Park, Nigeria...
2017: PloS One
https://www.readbyqxmd.com/read/28323065/the-impact-of-fecal-sample-processing-on-prevalence-estimates-for-antibiotic-resistant-escherichia-coli
#3
Sylvia Omulo, Eric T Lofgren, Maina Mugoh, Moshe Alando, Joshua Obiya, Korir Kipyegon, Gilbert Kikwai, Wilson Gumbi, Samuel Kariuki, Douglas R Call
Investigators often rely on studies of Escherichia coli to characterize the burden of antibiotic resistance in a clinical or community setting. To determine if prevalence estimates for antibiotic resistance are sensitive to sample handling and interpretive criteria, we collected presumptive E. coli isolates (24 or 95 per stool sample) from a community in an urban informal settlement in Kenya. Isolates were tested for susceptibility to nine antibiotics using agar breakpoint assays and results were analyzed using generalized linear mixed models...
March 18, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28322629/promoting-the-wellbeing-of-lesbian-gay-bisexual-and-transgender-forced-migrants-in-canada-providers-perspectives
#4
Sarilee Kahn, Edward Alessi, Leah Woolner, Hanna Kim, Christina Olivieri
Researchers are beginning to document the experiences of lesbian, gay, bisexual and transgender (LGBT) forced migrants in settlement. However, studies exploring the perceptions of service providers working with this vulnerable population are limited. These may shed light on the challenges of meeting the needs of LGBT forced migrants, especially mental health issues and problems. This qualitative study elicited the views of 22 Canadian service providers, including advocates, lawyers and mental health practitioners, who serve LGBT forced migrants...
March 21, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28321877/pharmacological-interventions-for-acute-hepatitis-b-infection-an-attempted-network-meta-analysis
#5
REVIEW
Konstantinos Mantzoukis, Manuel Rodríguez-Perálvarez, Elena Buzzetti, Douglas Thorburn, Brian R Davidson, Emmanuel Tsochatzis, Kurinchi Selvan Gurusamy
BACKGROUND: Infection with hepatitis B virus (HBV) can be symptomatic or asymptomatic. Apart from chronic HBV infection, the complications related to acute HBV infection are severe acute viral hepatitis and fulminant hepatitis characterised by liver failure. The optimal pharmacological treatment of acute HBV infection remains controversial. OBJECTIVES: To assess the benefits and harms of pharmacological interventions in the treatment of acute HBV infection through a network meta-analysis and to generate rankings of the available treatments according to their safety and efficacy...
March 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28320529/prevalence-of-neuropathic-pain-in-knee-or-hip-osteoarthritis-a-systematic-review-and-meta-analysis
#6
REVIEW
Helen P French, Keith M Smart, Frank Doyle
OBJECTIVE: Discordance between radiographic and pain severity in osteoarthritis (OA) has led researchers to investigate other pain mechanisms, including neuropathic pain. Accurate identification of any neuropathic pain in hip or knee OA is important for appropriate management, but neuropathic pain prevalence is unknown. We aimed to obtain an overall prevalence estimate by systematically reviewing and meta-analysing the prevalence of neuropathic pain in people with hip or knee OA. METHOD: Observational studies which measured neuropathic pain in people aged 18 years and older with hip or knee OA were considered for inclusion...
February 20, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28315607/correcting-bias-due-to-missing-stage-data-in-the-non-parametric-estimation-of-stage-specific-net-survival-for-colorectal-cancer-using-multiple-imputation
#7
Milena Falcaro, James R Carpenter
BACKGROUND: Population-based net survival by tumour stage at diagnosis is a key measure in cancer surveillance. Unfortunately, data on tumour stage are often missing for a non-negligible proportion of patients and the mechanism giving rise to the missingness is usually anything but completely at random. In this setting, restricting analysis to the subset of complete records gives typically biased results. Multiple imputation is a promising practical approach to the issues raised by the missing data, but its use in conjunction with the Pohar-Perme method for estimating net survival has not been formally evaluated...
March 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28302139/targeted-temperature-management-in-cardiac-arrest-survival-evaluated-by-propensity-score-matching
#8
Eirik A Buanes, Karl O Hufthammer, Jørund Langørgen, Anne-Berit Guttormsen, Jon-Kenneth Heltne
BACKGROUND: Targeted temperature management in cardiac arrest was introduced following evidence of increased survival from two controlled trials published in 2002. We wanted to investigate whether the introduction of targeted temperature management to clinical practice had increased the survival of cardiac arrest patients at Haukeland University Hospital, Norway. METHODS: We included 336 unresponsive patients admitted to the emergency department between December 2003 and December 2008 with return of spontaneous circulation following out-of-hospital cardiac arrest in the analysis...
March 16, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28301596/screening-for-interaction-effects-in-gene-expression-data
#9
Peter J Castaldi, Michael H Cho, Liming Liang, Edwin K Silverman, Craig P Hersh, Kenneth Rice, Hugues Aschard
Expression quantitative trait (eQTL) studies are a powerful tool for identifying genetic variants that affect levels of messenger RNA. Since gene expression is controlled by a complex network of gene-regulating factors, one way to identify these factors is to search for interaction effects between genetic variants and mRNA levels of transcription factors (TFs) and their respective target genes. However, identification of interaction effects in gene expression data pose a variety of methodological challenges, and it has become clear that such analyses should be conducted and interpreted with caution...
2017: PloS One
https://www.readbyqxmd.com/read/28301100/comparison-of-mr-flow-quantification-in-peripheral-and-main-pulmonary-arteries-in-patients-after-right-ventricular-outflow-tract-surgery-a-retrospective-study
#10
Tobias Rutz, Christian Meierhofer, Susanne Naumann, Stefan Martinoff, Peter Ewert, Heiko C Stern, Sohrab Fratz
PURPOSE: To compare the quantification of pulmonary stroke volume (SV) by phase contrast magnetic resonance (PC-MR) in the main pulmonary artery (MPA) to the sum of SVs in both peripheral pulmonary arteries (PPA) in different right ventricular (RV) outflow pathologies. MATERIALS AND METHODS: Pulmonary SV was determined by PC-MR in the MPA and the PPA in healthy individuals (H, n = 54), patients after correction for tetralogy of Fallot with significant pulmonary regurgitation and without pulmonary or RV outflow tract stenosis (PR, n = 50), and in patients with RV outflow tract or pulmonary valve stenosis (PS, n = 50)...
March 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28300431/the-psychometric-costs-of-applicants-faking-examining-measurement-invariance-and-retest-correlations-across-response-conditions
#11
Georg Krammer, Markus Sommer, Martin E Arendasy
This study examines the stability of the response process and the rank-order of respondents responding to 3 personality scales in 4 different response conditions. Applicants to the University College of Teacher Education Styria (N = 243) completed personality scales as part of their college admission process. Half a year later, they retook the same personality scales in 1 of 3 randomly assigned experimental response conditions: honest, faking-good, or reproduce. Longitudinal means and covariance structure analyses showed that applicants' response processes could be partially reproduced after half a year, and respondents seemed to rely on an honest response behavior as a frame of reference...
March 16, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28299526/interpretation-bias-training-in-depressed-adolescents-near-and-far-transfer-effects
#12
Joelle LeMoult, Natalie Colich, Jutta Joormann, Manpreet K Singh, Caitlin Eggleston, Ian H Gotlib
Depressed adolescents are characterized by negative interpretation biases. Although investigators have used cognitive bias modification for interpretation (CBM-I) to experimentally manipulate interpretation biases in depressed adults, the near- and far-transfer effects are not well understood in adolescents diagnosed with Major Depressive Disorder (MDD). In this study, we extend previous research by investigating the near- and far-transfer effects of 6 sessions of Positive versus Neutral CBM-I on independent measures of interpretation bias (near-transfer effects) and on attention biases and clinical symptoms (far-transfer effects) in a sample of adolescents with MDD (n = 46)...
March 15, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28298995/the-all-on-four-treatment-concept-systematic-review
#13
REVIEW
David Soto-Penaloza, Regino Zaragozí-Alonso, María Penarrocha-Diago, Miguel Penarrocha-Diago
OBJECTIVES: To systematically review the literature on the "all-on-four" treatment concept regarding its indications, surgical procedures, prosthetic protocols and technical and biological complications after at least three years in function. STUDY DESIGN: The three major electronic databases were screened: MEDLINE (via PubMed), EMBASE, and the Cochrane Library of the Cochrane Collaboration (CENTRAL). In addition, electronic screening was made of the 'grey literature' using the System for Information on Grey Literature in Europe - Open Grey, covering the period from January 2005 up to and including April 2016...
March 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28298210/delineating-functional-principles-of-the-bow-tie-structure-of-a-kinase-phosphatase-network-in-the-budding-yeast
#14
Diala Abd-Rabbo, Stephen W Michnick
BACKGROUND: Kinases and phosphatases (KP) form complex self-regulating networks essential for cellular signal processing. In spite of having a wealth of data about interactions among KPs and their substrates, we have very limited models of the structures of the directed networks they form and consequently our ability to formulate hypotheses about how their structure determines the flow of information in these networks is restricted. RESULTS: We assembled and studied the largest bona fide kinase-phosphatase network (KP-Net) known to date for the yeast Saccharomyces cerevisiae...
March 16, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/28295758/internet-interventions-for-adult-illicit-substance-users-a-meta-analysis
#15
REVIEW
Nikolaos Boumparis, Eirini Karyotaki, Michael P Schaub, Pim Cuijpers, Heleen Riper
BACKGROUND AND AIMS: Research has shown that internet interventions can be effective for dependent users of various substances. However, less is known about the effects of these interventions on users of opioids, cocaine, and amphetamines than for other substances. We aimed to investigate the effectiveness of internet interventions in decreasing the usage of these types of substances. METHODS: We conducted a systematic literature search in the databases of PubMed, PsycINFO, Embase, and the Cochrane Library to identify randomized controlled trials examining the effectiveness of internet interventions compared with control conditions in reducing the use of opioids, cocaine, and amphetamines...
March 10, 2017: Addiction
https://www.readbyqxmd.com/read/28294136/opioid-modulation-of-value-based-decision-making-in-healthy-humans
#16
Marie Eikemo, Guido Biele, Frode Willoch, Lotte Thomsen, Siri Leknes
Modifying behavior to maximize reward is integral to adaptive decision making. In rodents, the μ-opioid receptor (MOR) system encodes motivation and preference for high-value rewards. Yet it remains unclear whether and how human MORs contribute to value-based decision making. We reasoned that if the human MOR system modulates value-based choice, this would be reflected by opposite effects of agonist and antagonist drugs. In a double-blind pharmacological cross-over study, 30 healthy men received morphine (10 mg), placebo and the opioid antagonist naltrexone (50 mg)...
March 15, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28292193/raters-interpret-positively-and-negatively-worded-items-similarly-in-a-quality-of-life-instrument-for-children
#17
Chung-Ying Lin, Carol Strong, Meng-Che Tsai, Chih-Ting Lee
Measurement invariance is an important assumption to meaningfully compare children's quality of life (QoL) between different raters (eg, children and parents) and across genders. Moreover, QoL instruments may combine using negatively and positively worded items-a common method to reduce response bias. However, the wording effects may have different levels of impact on different raters and genders. Our aim was to investigate the measurement invariance of Kid-KINDL, a commonly used QoL instrument, across genders and raters and to consider the wording effects simultaneously...
January 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28290160/risk-scoring-for-the-primary-prevention-of-cardiovascular-disease
#18
REVIEW
Kunal N Karmali, Stephen D Persell, Pablo Perel, Donald M Lloyd-Jones, Mark A Berendsen, Mark D Huffman
BACKGROUND: The current paradigm for cardiovascular disease (CVD) emphasises absolute risk assessment to guide treatment decisions in primary prevention. Although the derivation and validation of multivariable risk assessment tools, or CVD risk scores, have attracted considerable attention, their effect on clinical outcomes is uncertain. OBJECTIVES: To assess the effects of evaluating and providing CVD risk scores in adults without prevalent CVD on cardiovascular outcomes, risk factor levels, preventive medication prescribing, and health behaviours...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28289887/bilingual-comparison-of-mandarin-and-english-cognitive-bias-tasks
#19
Louise Smith, Wing Gi Leung, Bryony Crane, Brian Parkinson, Timothea Toulopoulou, Jenny Yiend
Most research into cognitive biases has used Western samples, despite potential East-West socio-cultural differences. One reason is the lack of appropriate measures for non-Westerners. This study is about cross-linguistic equivalence which needs to be established before assessing cross-cultural differences in future research. We developed parallel Mandarin and English measures of interpretation bias and attention bias using back-translation and decentering procedures. We assessed task equivalence by administering both sets of measures to 47 bilingual Mandarin-English speakers...
March 13, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28289564/binsanity-unsupervised-clustering-of-environmental-microbial-assemblies-using-coverage-and-affinity-propagation
#20
Elaina D Graham, John F Heidelberg, Benjamin J Tully
Metagenomics has become an integral part of defining microbial diversity in various environments. Many ecosystems have characteristically low biomass and few cultured representatives. Linking potential metabolisms to phylogeny in environmental microorganisms is important for interpreting microbial community functions and the impacts these communities have on geochemical cycles. However, with metagenomic studies there is the computational hurdle of 'binning' contigs into phylogenetically related units or putative genomes...
2017: PeerJ
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