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https://www.readbyqxmd.com/read/28919252/mutation-in-the-peroxin-coding-gene-pex22-contributing-to-high-malate-production-in-saccharomyces-cerevisiae
#1
Hiroaki Negoro, Mitsuru Sakamoto, Atsushi Kotaka, Kengo Matsumura, Yoji Hata
Saccharomyces cerevisiae produces organic acids such as succinate, acetate, and malate during alcoholic fermentation. Since malate contributes to the pleasant taste of sake (a Japanese alcoholic beverage), various methods for breeding high-malate-producing yeast strains have been developed. Here, a high-malate-producing yeast strain F-701H was isolated. This mutant was sensitive to dimethyl succinate (DMS) and harbored a nonsense mutation in the peroxin gene PEX22, which was identified as the cause of high malate production by comparative genome analysis...
September 14, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28915966/use-of-anthropogenic-nitrogen-fertilizers-in-agriculture-is-associated-with-per-capita-ethanol-consumption
#2
Keith Fluegge, Kyle Fluegge
It has previously been demonstrated that emissions of the agricultural pollutant, nitrous oxide (N2O), may be a confounder to the relationship between herbicide use and psychiatric impairments, including ADHD. This report attempts to extend this hypothesis by testing whether annual use of anthropogenic nitrogen-based fertilizers in U.S. agriculture (thought to be the most reliable indicator of environmental N2O emissions) is associated with per capita ethanol consumption patterns, a behavior often comorbid with ADHD...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28913331/health-effects-and-public-health-concerns-of-energy-drink-consumption-in-the-united-states-a-mini-review
#3
REVIEW
Laila Al-Shaar, Kelsey Vercammen, Chang Lu, Scott Richardson, Martha Tamez, Josiemer Mattei
As energy drink consumption continues to grow worldwide and within the United States, it is important to critically examine the nutritional content and effects on population health of these beverages. This mini-review summarizes the current scientific evidence on health consequences from energy drink consumption, presents relevant public health challenges, and proposes recommendations to mitigate these issues. Emerging evidence has linked energy drink consumption with a number of negative health consequences such as risk-seeking behaviors, poor mental health, adverse cardiovascular effects, and metabolic, renal, or dental conditions...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28910991/pricing-as-a-means-of-controlling-alcohol-consumption
#4
Anurag Sharma, Kompal Sinha, Brian Vandenberg
Background: Reducing the affordability of alcohol, by increasing its price, is the most effective strategy for controlling alcohol consumption and reducing harm. Sources of data: We review meta-analyses and systematic reviews of alcohol tax/price effects from the past decade, and recent evaluations of tax/price policies in the UK, Canada and Australia. Areas of agreement: While the magnitudes of price effects vary by sub-group and alcoholic beverage type, it has been consistently shown that price increases lead to reductions in alcohol consumption...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28910546/could-hop-derived-bitter-compounds-improve-glucose-homeostasis-by-stimulating-the-secretion-of-glp-1
#5
Luigi Barrea, Giuseppe Annunziata, Giovanna Muscogiuri, Angela Arnone, Gian Carlo Tenore, Annamaria Colao, Silvia Savastano
Hops (Humulus lupulus L.) is by far the greatest contributors to the bitter property of beer. Over the past years, a large body of evidence demonstrated the presence of taste receptors in different locations of the oral cavity. In addition to the taste buds of the tongue, cells expressing these receptors have been identified in olfactory bulbs, respiratory and gastrointestinal tract. In the gut, the attention was mainly directed to sweet Taste Receptor (T1R) and bitter Taste Receptor (T2R) receptors. In particular, T2R has shown to modulate secretion of different gut hormones, mainly Glucagon-like Peptide 1 (GLP-1), which are involved in the regulation of glucose homeostasis and the control of gut motility, thereby increasing the sense of satiety...
September 14, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28891965/molecular-mechanisms-of-acetaldehyde-mediated-carcinogenesis-in-squamous-epithelium
#6
REVIEW
Ayaka Mizumoto, Shinya Ohashi, Kenshiro Hirohashi, Yusuke Amanuma, Tomonari Matsuda, Manabu Muto
Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA, including DNA adducts, single- and/or double-strand breaks (DSBs), point mutations, sister chromatid exchanges (SCEs), and DNA-DNA cross-links. Among these, DNA adducts such as N²-ethylidene-2'-deoxyguanosine, N²-ethyl-2'-deoxyguanosine, N²-propano-2'-deoxyguanosine, and N²-etheno-2'-deoxyguanosine are central to acetaldehyde-mediated DNA damage because they are associated with the induction of DNA mutations, DNA-DNA cross-links, DSBs, and SCEs...
September 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28891383/a-hypothesis-moderate-consumption-of-alcoholic-beverages-contributes-to-lower-prevalence-of-type-2-diabetes-t2dm-due-to-scavenging-of-%C3%AE-dicarbonyls-by-several-classes-of-dietary-phytochemicals
#7
Benjamin S Szwergold
The world is experiencing an epidemic of Type-2-Diabetes (T2DM). This has led to increased morbidity and mortality, explosive growth in heath-care budgets and has an even greater, if indirect, impact on societies and economies of the affected countries. While genetic susceptibility to T2DM is a major determinant of its prevalence, changes in life-styles also play a role. One such change has been a transition from traditional diets characterized by low caloric and high nutrient density to calorie-rich but nutrient-poor Western diets...
September 11, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/28888446/changes-in-anthocyanins-and-volatile-components-of-purple-sweet-potato-fermented-alcoholic-beverage-during-aging
#8
Suhong Li, Yingfeng An, Weina Fu, Xiao Sun, Wenjie Li, Tuoping Li
Purple sweet potato was fermented into alcoholic beverage. By using LC-MS analysis, 12 types of anthocyanins were found in the purple sweet potato alcoholic beverage (PSPFAB); these were based on cyanidin and peonidin as aglycones. The anthocyanins in young PSPFAB mainly consisted of acylates. The acylated anthocyanins, however, degraded gradually with aging. Cyanidin 3-sophoroside-5-glucoside and peonidin 3-sophoroside-5-glucoside were found to be major anthocyanins in the PSPFAB after two years of aging. Moreover, 52 kinds of volatile components were detected in PSPFAB by GC-MS analysis...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28888149/the-impact-of-alcohol-policies-on-alcohol-attributable-diseases-in-taiwan-a-population-based-study
#9
Yung-Hsiang Ying, Yung-Ching Weng, Koyin Chang
BACKGROUND: Taiwan has some of the strictest alcohol-related driving laws in the world. However, its laws continue to be toughened to reduce the ever-increasing social cost of alcohol-related harm. AIM: This study assumes that alcohol-related driving laws show a spillover effect such that behavioral changes originally meant to apply behind the wheel come to affect drinking behavior in other contexts. The effects of alcohol driving laws and taxes on alcohol-related morbidity are assessed; incidence rates of alcohol-attributable diseases (AAD) serve as our measure of morbidity...
September 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28887544/analysis-of-bacterial-and-fungal-communities-in-marcha-and-thiat-traditionally-prepared-amylolytic-starters-of-india
#10
Shankar Prasad Sha, Kunal Jani, Avinash Sharma, Anu Anupma, Pooja Pradhan, Yogesh Shouche, Jyoti Prakash Tamang
Marcha and thiat are traditionally prepared amylolytic starters use for production of various ethnic alcoholic beverages in Sikkim and Meghalaya states in India. In the present study we have tried to investigate the bacterial and fungal community composition of marcha and thiat by using high throughput sequencing. Characterization of bacterial community depicts phylum Proteobacteria is the most dominant in both marcha (91.4%) and thiat (53.8%), followed by Firmicutes, and Actinobacteria. Estimates of fungal community composition showed Ascomycota as the dominant phylum...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28885599/family-social-environment-and-parenting-predictors-of-alcohol-use-among-adolescents-in-lithuania
#11
Linas Šumskas, Apolinaras Zaborskis
The role of the family as the social environment in shaping adolescent lifestyle has recently received substantial attention. This study was focused on investigating the association between familial and parenting predictors and alcohol use in school-aged children. Adolescents aged 13- and 15-year from a representative sample (N = 3715) of schools in Lithuania were surveyed during the spring of 2014. The methodology of the cross-national Health Behaviour in School-aged Children (HBSC) study was applied. HBSC international questionnaires were completed in the classroom anonymously for obtaining information about drinking of alcoholic beverages and family characteristics-family's affluence and structure, style of communication in the family, parenting style, parental monitoring, family time together, etc...
September 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28883860/impact-of-beverage-consumption-age-and-site-dependency-on-dual-energy-x-ray-absorptiometry-dexa-measurements-in-perimenopausal-women-a-prospective-study
#12
Huan-Chu Lo, Duen-Pang Kuo, Yen-Lin Chen
INTRODUCTION: The aim of this study was to determine the best site for bone mineral density (BMD) measurements based on T-scores, age, and beverage consumption. MATERIAL AND METHODS: In this prospective study, 271 women stratified by age (average age: 61.9 years) underwent dual energy X-ray absorptiometry (DEXA) scanning of their lumbar spine, hips, and forearms. Osteoporosis was defined as a BMD of 2.5 standard deviations or more below the mean peak bone mass based on a reference population of adult women (translated as a T-score ≤ -2...
August 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28882342/the-analysis-of-aroma-flavor-compounds-in-green-tea-using-ice-concentration-linked-with-extractive-stirrer
#13
Abdullah H Alluhayb, Brian A Logue
Worldwide, green tea is one of the most popular beverages. It promotes blood circulation, liver function, and lowers the risk of cancer and cardiovascular diseases. This drink is characterized by the distinctive odors and flavors produced by its constituent compounds, with its value predicated on the amount and type of constituents extracted from the tea leaves during brewing. Ice concentration linked with extractive stirrer (ICECLES) is a novel sample preparation technique, especially applicable for the extraction of relatively polar compounds while retaining excellent extraction efficiencies for non-polar compounds...
August 25, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28875062/interactions-between-energy-drink-consumption-and-sleep-problems-associations-with-alcohol-use-among-young-adolescents
#14
Naomi R Marmorstein
Background: Energy drink consumption and sleep problems are both associated with alcohol use among adolescents. In addition, caffeine consumption (including energy drinks) is associated with sleep problems. However, information about how these three constructs may interact is limited. The goal of this study was to examine potential interactions between energy drink consumption and sleep problems in the concurrent prediction of alcohol use among young adolescents. Coffee and soda consumption were also examined for comparison...
September 1, 2017: Journal of Caffeine Research
https://www.readbyqxmd.com/read/28873739/effect-of-symbiotic-interaction-between-a-fructooligosaccharide-and-probiotic-on-the-kinetic-fermentation-and-chemical-profile-of-maize-blended-rice-beverages
#15
Ana Luiza Freire, Cintia Lacerda Ramos, Rosane Freitas Schwan
There is an important demand for the development of new non-dairy probiotic beverages in the functional food market. This work aimed to develop new fermented beverages from maize and rice. Lactobacillus plantarum CCMA 0743, Torulaspora delbrueckii CCMA 0235, and the commercial probiotic Lactobacillus acidophilus LACA 4, were used as a mixed starter culture. Two prebiotic concentrations, 20 and 50g/L fructooligosaccharide (FOS) were tested. The growth of L. acidophilus LACA 4 was favored by 50g/L FOS and after refrigerated storage at 4°C for 28days, its population remained above 10(7)CFU/mL...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873614/flavor-and-chiral-stability-of-lemon-flavored-hard-tea-during-storage
#16
Fei He, YanPing L Qian, Michael C Qian
Flavor stability of hard tea beverage was investigated over eight weeks of storage. The volatile compounds were analyzed using solid-phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS) and two-dimensional GC-MS. Quantitative analysis showed that the concentrations of linalool, citronellol, geranial, neral, geraniol, and nerol decreased dramatically during storage, whereas α-terpineol showed an increasing trend during storage. Heart-cut two-dimensional GC-MS (2D-GC-MS) chirality analysis showed that (R)-(+)-limonene, (R)-(-)-linalool, (S)-(-)-α-terpineol and (S)-(-)-4-terpineol dominated in the fresh hard tea samples, however, the configuration changed during storage for the terpene alcohols...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28862539/lead-pb-exposure-induces-disturbances-in-epigenetic-status-in-workers-exposed-to-this-metal
#17
Paula Pícoli Devóz, Willian Robert Gomes, Marília Ladeira De Araújo, Diego Luis Ribeiro, Tatiana Pedron, Lusânia Maria Greggi Antunes, Bruno Lemos Batista, Fernando Barbosa, Gustavo Rafael Mazzaron Barcelos
Previous studies showed that lead (Pb) exposure may modulate gene expression by changes in the epigenetic status. However, little is known about the impact of Pb exposure and alterations on DNA methylation patterns in humans exposed to this metal. The aim of this study was to assess the consequences of exposure to Pb on DNA global methylation, in order to gain a better understanding of the interactions between Pb exposure and epigenetic effects. The study included 100 male workers employed in automotive battery factories from Paraná State, Brazil...
September 1, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28862229/prevalence-of-tobacco-in-darbhanga-district-a-hospital-based-cross-sectional-study
#18
Jatin Gupta, Swarnalatha J Wesly, Kanupriya Gupta
INTRODUCTION: Chewing tobacco, smoking, and consumption of alcoholic beverages have become common social habits in India. No study has been conducted so far in this part of Bihar regarding the prevalence of tobacco. The aim of this study was to estimate the prevalence of tobacco use, its influences, triggers, and associated oral lesions. MATERIALS AND METHODS: A hospital-based cross-sectional study was conducted. Patients who consume tobacco in any form were selected and were interviewed through a pretested structured questionnaire in relation to their tobacco habits, its influences, and triggers...
July 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28854726/the-association-between-pre-treatment-maternal-alcohol-and-caffeine-intake-and-outcomes-of-assisted-reproduction-in-a-prospectively-followed-cohort
#19
L Abadia, Y-H Chiu, P L Williams, T L Toth, I Souter, R Hauser, J E Chavarro, A J Gaskins
STUDY QUESTION: Is pre-treatment alcohol and caffeine intake associated with infertility treatment outcomes among women undergoing ART? SUMMARY ANSWER: Low to moderate alcohol and caffeine intakes in the year prior to infertility treatment were not related to ART outcomes. WHAT IS KNOWN ALREADY: Alcohol and caffeine intake have been found to be associated with infertility in some studies. Nevertheless, data on their relation with outcomes of infertility treatments are scarce and inconsistent...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28854708/rapidly-increasing-trend-of-recorded-alcohol-consumption-since-the-end-of-the-armed-conflict-in-sri-lanka
#20
Manjula D Nugawela, Sarah Lewis, Lisa Szatkowski, Tessa Langley
Aim: To evaluate temporal changes in recorded alcohol consumption in Sri Lanka during and after the armed conflict 1998-2013. Methods: District level alcohol sales, and mid-year population data for the whole study period (1998-2013) were consistently available from the Department of Excise and the Department of Census and Statistics for 18 of 25 districts. These data were used to estimate the recorded per capita consumption for the areas that were not directly exposed to the armed conflict...
September 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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