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https://www.readbyqxmd.com/read/28732322/effects-of-environmental-pollutants-on-signaling-pathways-in-rat-pituitary-gh3-adenoma-cells
#1
Nicoletta Fortunati, Federica Guaraldi, Valentina Zunino, Federica Penner, Valentina D'Angelo, Francesco Zenga, Francesca Pecori Giraldi, Maria Graziella Catalano, Emanuela Arvat
An increased rate of acromegaly was reported in industrialized areas, suggesting an involvement of environmental pollutants in the pathogenesis and behavior of GH-secreting pituitary adenomas. Based on these premises, the aim of the study was to evaluate the effects of some widely diffused pollutants (i.e. benzene, BZ; bis(2-ethylhexyl) phthalate, DEHP and polychlorinated biphenyls, PCB) on growth hormone secretion, the somatostatin and estrogenic pathways, viability and proliferation of rat GH-producing pituitary adenoma (GH3) cells...
July 18, 2017: Environmental Research
https://www.readbyqxmd.com/read/28729632/erratum-removal-of-diethylhexyl-phthalate-from-hands-by-handwashing-evidence-from-experimental-n-of-1-and-crossover-designs
#2
Pi-I D Lin, Chia-Fang Wu, Hwang-Shang Kou, Tzu-Ying Huang, Jentaie Shiea, Ming-Tsang Wu
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728088/phthalate-and-non-phthalate-plasticizers-in-indoor-dust-from-childcare-facilities-salons-and-homes-across-the-usa
#3
Bikram Subedi, Kenneth D Sullivan, Birendra Dhungana
The quality of indoor environment has received considerable attention owing to the declining outdoor human activities and the associated public health issues. The prolonged exposure of children in childcare facilities or the occupational exposure of adults to indoor environmental triggers can be a culprit of the pathophysiology of several commonly observed idiopathic syndromes. In this study, concentrations of potentially toxic plasticizers (phthalates as well as non-phthalates) were investigated in 28 dust samples collected from three different indoor environments across the USA...
July 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28727988/environmental-exposures-and-pediatric-kidney-function-and-disease-a-systematic-review
#4
REVIEW
Laura Y Zheng, Alison P Sanders, Jeffrey M Saland, Robert O Wright, Manish Arora
BACKGROUND: Environmental chemical exposures have been implicated in pediatric kidney disease. No appraisal of the available evidence has been conducted on this topic. METHODS: We performed a systematic review of the epidemiologic studies that assessed association of environmental exposures with measures of kidney function and disease in pediatric populations. The search period went through July 2016. RESULTS: We found 50 studies that met the search criteria and were included in this systematic review...
July 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/28724251/concurrent-exposures-to-nonylphenol-bisphenol-a-phthalates-and-organophosphate-pesticides-on-birth-outcomes-a-cohort-study-in-taipei-taiwan
#5
Yu-Fang Huang, Wen-Chi Pan, Yen-An Tsai, Chia-Huang Chang, Pei-Jung Chen, Yi-Shuan Shao, Ming-Song Tsai, Jia-Woei Hou, Chensheng Alex Lu, Mei-Lien Chen
Prenatal exposure to phenols, phthalates (PAEs), and organophosphate (OP) pesticides may increase the risk of abnormal birth outcomes. However, many previous studies have examined exposure to a limited number of chemical classes or exposure profiles limited to a specific stage of pregnancy. This study aims to characterize the concurrent exposure scenario throughout pregnancy by simultaneously monitoring internal doses of several endocrine-disrupting compounds (EDCs), including 2 phenols (nonylphenol (NP) and bisphenol A (BPA)), 9 PAEs, and 6 OP pesticide metabolites and to assess the relationships between concurrent exposure to EDCs and infant birth weight, length, and head and chest circumference...
July 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28719870/effects-of-endocrine-disrupting-chemicals-on-estrogen-receptor-alpha-and-heat-shock-protein-60-gene-expression-in-primary-cultures-of-loggerhead-sea-turtle-caretta-caretta-erythrocytes
#6
Paolo Cocci, Martina Capriotti, Gilberto Mosconi, Francesco Alessandro Palermo
The loggerhead turtle (Caretta caretta) can be considered a good indicator species for studying the ecological impact of endocrine disrupting chemicals (EDCs) on wildlife. However, the effect of these environmental pollutants on nuclear steroid hormone signaling has not yet been addressed in sea turtles mainly due to the legal constraints of their endangered status. Here we describe the use of primary erythrocyte cell cultures as in vitro models for evaluating the effects of different EDCs on the expression of estrogen receptor α (ERα)...
July 15, 2017: Environmental Research
https://www.readbyqxmd.com/read/28719472/contact-sensitization-to-allergens-in-nail-cosmetics
#7
Margaret Chou, Nikhil Dhingra, Tamara Lazic Strugar
Ingredients found in the nail cosmetic industry, including but not limited to methacrylate and acrylate monomers, formaldehyde, and toluene sulfonamide-formaldehyde resin, can incite allergic contact dermatitis. An eczematous outbreak presents on areas surrounding the nail plate and may spread through contact transfer of the allergen, commonly to the face and neck. Even components that were originally deemed nonsensitizing, such as the ubiquitous cyanoacrylate adhesive family, have been found to be allergenic...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28717333/analysis-of-chemical-signatures-of-alkaliphiles-using-fatty-acid-methyl-ester-analysis
#8
Basha Sreenivasulu, Chinthala Paramageetham, Dasari Sreenivasulu, Bukke Suman, Katike Umamahesh, Gundala Prasada Babu
BACKGROUND: Fatty acids occur in nearly all living organisms as the important predominant constituents of lipids. While all fatty acids have essentially the same chemical nature, they are an extremely diverse group of compounds. MATERIALS AND METHODS: To test the hypothesis, fatty acids of alkaliphiles isolates, Bacillus subtilis SVUNM4, Bacillus licheniformis SVUNM8, Bacillus methylotrohicus SVUNM9, and Paenibacillus dendritiformis SVUNM11, were characterized compared using gas chromatography-mass spectrometry (GC-MS) analysis...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717100/inhibitory-modulation-of-human-estrogen-receptor-%C3%AE-and-%C3%AE-activities-by-dicyclohexyl-phthalate-in-human-breast-cancer-cell-lines
#9
Hiroyuki Okazaki, Shuso Takeda, Saki Matsuo, Masaya Matsumoto, Erika Furuta, Eriko Kohro-Ikeda, Hironori Aramaki
Phthalate esters (PAEs) are man-made compounds that are used widely in industry, and the ubiquitous exposure of humans to PAEs has been reported. Although some PAEs have been suggested to function as xenoestrogens in in vitro systems, such as human estrogen receptors (ERs) expressed in Chinese hamster ovary (CHO)-K1 cells, few studies have attempted to elucidate whether PAEs affect human ERα/ERβ-mediated signaling in human breast cancer cells (i.e., combination between human ERs and human cells). Thus, further experiments are needed in order to clarify the activities of PAEs...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/28715785/prenatal-exposure-estimation-of-bpa-and-dehp-using-integrated-external-and-internal-dosimetry-a-case-study
#10
M A Martínez, J Rovira, R Prasad Sharma, M Nadal, M Schuhmacher, V Kumar
Prenatal exposure to Endocrine disruptors (EDs), such as Bisphenol A (BPA) and di (2-ethylhexyl) phthalate (DEHP), has been associated with obesity and diabetes diseases in childhood, as well as reproductive, behavioral and neurodevelopment problems. The aim of this study was to estimate the prenatal exposure to BPA and DEHP through food consumption for pregnant women living in Tarragona County (Spain). Probabilistic calculations of prenatal exposure were estimated by integrated external and internal dosimetry modelling, physiologically based pharmacokinetic (PBPK) model, using a Monte-Carlo simulation...
July 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/28714600/phytic-acid-induced-three-dimensional-graphene-for-the-enrichment-of-phthalate-esters-from-bottled-water-and-sports-beverage-samples
#11
Xinyu Liang, Juntao Wang, Juanjuan Wu, Qiuhua Wu, Chun Wang, Zhi Wang
A three-dimensional graphene was synthesized through a hydrothermal reaction of graphene oxide with phytic acid. The microstructure and morphology of the phytic acid induced three-dimensional graphene were investigated by nitrogen adsorption-desorption isotherms, scanning electron microscopy and transmission electron microscopy. With a large surface area and three-dimensional structure, the graphene was used as the solid-phase extraction adsorbent for the extraction of phthalate esters from bottled water and sports beverage samples before high-performance liquid chromatographic analysis...
July 17, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28714305/a-spme-based-ca-history-method-for-measuring-svoc-diffusion-coefficients-in-clothing-material
#12
Jianping Cao, Ningrui Liu, Yinping Zhang
Clothes play an important role in dermal exposure to indoor semi-volatile organic compounds (SVOCs). The diffusion coefficient of SVOCs in clothing material (Dm) is essential for estimating SVOC sorption by clothing material and subsequent dermal exposure to SVOCs. However, few studies have reported the measured Dm for clothing materials. In this paper, we present the solid-phase micro-extraction (SPME) based Ca-history method. To the best of our knowledge, this is the first try to measure Dm with known relative standard deviation (RSD)...
July 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28712773/spatial-distribution-and-seasonal-variation-of-phthalate-esters-in-the-jiulong-river-estuary-southeast-china
#13
Rongli Li, Jing Liang, Hualing Duan, Zhenbin Gong
The spatial distribution and seasonal variation of 16 phthalate esters (PAEs) in water, suspended particulate matter (SPM) and sediment were investigated in the Jiulong River estuary, Fujian, Southeast China. Of the 16 PAE congeners analyzed, only six PAEs, including dimethyl phthalate (DMP), diethyl phthalate (DEP), diisobutyl phthalate (DIBP), di-n-butyl phthalate (DBP), di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP), were identified and quantified. The total concentrations of the six PAEs (∑6PAEs) detected for all seasons ranged from 3...
July 13, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28711850/urinary-phthalate-metabolites-over-the-first-15months-of-life-and-risk-assessment-check-cohort-study
#14
Sunmi Kim, Jangwoo Lee, Jeongim Park, Hai-Joong Kim, Geum Joon Cho, Gun-Ha Kim, So-Hee Eun, Jeong Jae Lee, Gyuyeon Choi, Eunsook Suh, Sooran Choi, Sungjoo Kim, Sung Koo Kim, Young Don Kim, Su Young Kim, Seunghyo Kim, Soyong Eom, Hyo-Bang Moon, Sungkyoon Kim, Kyungho Choi
Phthalates are important group of endocrine disruptors. Infants and young children are susceptible to phthalate exposure. However, information on the phthalate exposure during the early stages of life is very limited. This study was conducted to understand the temporal trend of exposure to major phthalates among infants of Korea during the first 15months after birth, and to estimate associated risks. A total of 286 urine samples were collected from 171 children at 3, 9, 12, or 15months of age, with 77 children sampled for two or more times...
July 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28705628/characteristics-and-sources-of-anthropogenic-and-biogenic-hydrocarbons-in-sediments-from-the-coast-of-qatar
#15
Ahmed I Rushdi, Ismail Al-Shaikh, Aarif H El-Mubarak, Hajer A J A Alnaimi, Noora Al-Shamary, Hassan M Hassan, Mazen Abou Assali
Surface sediment samples from the coastal zone of Qatar were collected and analyzed to determine the characteristics, and sources of anthropogenic and biogenic hydrocarbons. The main compounds in these surface sediments included n-alkanes, methyl n-alkanoates, diterpenoids, hopanes, steranes, phthalate esters, polycyclic aromatic hydrocarbons (PAHs) and unresolved complex mixture (UCM). Their total concentrations ranged from 18.7±3.7-81.1±7.5ng/g (3.7±0.6-10.4±4.8%) for n-alkanes, 8.3±2.3-51±3.4ng/g (3...
July 10, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28702673/unexpected-thermal-annealing-effects-on-the-viscosity-of-polymer-nanocomposites
#16
Fei Chen, Koshu Takatsuji, Dan Zhao, Xuanji Yu, Sanat K Kumar, Ophelia K C Tsui
The effects of thermal annealing, 12-50 K above the glass transition temperature, on the zero-shear viscosity, η, of polymer nanocomposites (PNCs) and the corresponding host polymers were studied. For all specimens, including neat and 4 wt% dioctyl phthalate (DOP)-plasticized polystyrene (PS), neat poly(methyl methacrylate) (PMMA), and PNCs containing bare and grafted silica nanoparticles in neat and DOP-plasticized PS, the η increased with time initially, and only asymptotically approached a steady-state value after thermal annealing for ∼100 to ∼200 h...
July 12, 2017: Soft Matter
https://www.readbyqxmd.com/read/28701071/sorption-of-organic-pollutants-frequently-detected-in-stormwater-evaluation-of-five-potential-sorbents
#17
Karin Björklund, Loretta Li
Adsorption filtration is one of the most promising techniques for removal of dissolved, colloidal and particulate pollutants from stormwater. The aim of this study was to compare the capacity of five filter materials - cellulose, chitosan, chitosan-covered bark, pine bark, and polypropylene/polyethylene (PP/PE) fibres - to sorb organic pollutants frequently detected in stormwater, including polycyclic aromatic hydrocarbons (PAHs), alkylphenols and phthalates. In batch tests, synthetic stormwater spiked with a mixture of the organic compounds was contacted with the materials for up to 24 h...
July 13, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28699343/characterization-of-adipogenic-activity-of-house-dust-extracts-and-semi-volatile-indoor-contaminants-in-3t3-l1-cells
#18
Christopher D Kassotis, Kate Hoffman, Heather M Stapleton
Obesity and metabolic disorders are of great societal concern and generate significant human health care costs. Recently, attention has focused on the potential for environmental contaminants to act as metabolic disruptors. This study sought to evaluate the adipogenic activity of indoor house dust extracts and a suite of semivolatile organic chemicals (SVOCs) that are often ubiquitously detected in indoor environments. 3T3-L1 cells were exposed to extracts of indoor dust or individual SVOCs and assessed for triglyceride accumulation and preadipocyte proliferation...
July 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28697387/influence-of-continental-organic-aerosols-to-the-marine-atmosphere-over-the-east-china-sea-insights-from-lipids-pahs-and-phthalates
#19
Mingjie Kang, Fan Yang, Hong Ren, Wanyu Zhao, Ye Zhao, Linjie Li, Yu Yan, Yingjie Zhang, Senchao Lai, Yingyi Zhang, Yang Yang, Zifa Wang, Yele Sun, Pingqing Fu
Total suspended particle (TSP) samples were collected during a marine cruise in the East China Sea from May 18 to June 12, 2014. They were analyzed for solvent extractable organic compounds (lipid compounds, PAHs and phthalates) using gas chromatography/mass spectrometry (GC/MS) to better understand the sources and source apportionment of aerosol pollution in the western North Pacific. Higher concentrations were observed in the terrestrially influenced aerosol samples on the basis of five-day backward air mass trajectories, especially for aerosols collected near coastal areas...
July 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28693824/dispersive-solid-phase-microextraction-with-graphene-oxide-based-molecularly-imprinted-polymers-for-determining-bis-2-ethylhexyl-phthalate-in-environmental-water
#20
Lidong Cheng, Shuihong Pan, Chuyuan Ding, Jun He, Chengjun Wang
A novel graphene oxide-molecularly imprinted polymers (GO-MIPs) was prepared and applied for selective extraction and preconcentration of bis(2-ethylhexyl) phthalate (DEHP) in environmental water samples by using the dispersive solid-phase microextraction (DSPME) method. The GO-MIPs was synthesized via precipitation polymerization using GO, DEHP, methacrylic acid, and ethylene dimethacrylate as supporting materials, template molecules, functional monomer, and cross-linker, respectively. The prepared GO-MIPs were characterized by scanning electron microscope and Fourier transform infrared spectroscopy...
July 6, 2017: Journal of Chromatography. A
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