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https://www.readbyqxmd.com/read/29141268/gastric-adenocarcinoma-and-proximal-polyposis-of-the-stomach-gapps-a-rare-recently-described-gastric-polyposis-syndrome-report-of-a-case
#1
Andrea Beer, Berthold Streubel, Reza Asari, Clemens Dejaco, Georg Oberhuber
In rare cases with multiple gastric polyps in the corpus and fundus, a recently described gastric polyposis syndrome called gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) has to be considered. We report on the findings in a patient fulfilling the criteria of this disease.A female patient born in 1977 underwent gastroscopy in 2005 due to recurrent abdominal pain. Endoscopy revealed more than 100 fundic gland polyps in the corpus and fundus. An ileocolonoscopy was inconspicuous. The patient did not take proton pump inhibitors...
November 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29140412/alcohol-consumption-and-lung-cancer-risk-in-never-smokers-a-pooled-analysis-of-case-control-studies
#2
José A García Lavandeira, Alberto Ruano-Ravina, Karl T Kelsey, María Torres-Durán, Isaura Parente-Lamelas, Virginia Leiro-Fernández, Maruxa Zapata, José Abal-Arca, Iria Vidal-García, Carmen Montero-Martínez, Margarita Amenedo, Olalla Castro-Añón, Antonio Golpe-Gómez, Rosirys Guzmán-Taveras, Cristina Martínez, Mariano Provencio, María J Mejuto-Martí, Silvia García-García, Alberto Fernández-Villar, María Piñeiro, Juan M Barros-Dios
Background: Lung cancer is the deadliest cancer in developed countries but the etiology of lung cancer risk in never smokers (LCRINS) is largely unknown. We aim to assess the effects of alcohol consumption, in its different forms, on LCRINS. Methods: We pooled six multi-center case-control studies developed in the northwest of Spain. Cases and controls groups were composed of never smokers. We selected incident cases with anatomopathologically confirmed lung cancer diagnoses...
November 13, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29137705/novel-approach-to-high-throughput-determination-of-endocrine-disruptors-using-recycled-diatomaceous-earth-as-a-green-sorbent-phase-for-thin-film-solid-phase-microextraction-combined-with-96-well-plate-system
#3
Nicolas Kirschner, Adriana Neves Dias, Dilma Budziak, Cristian Berto da Silveira, Josias Merib, Eduardo Carasek
A sustainable approach to TF-SPME is presented using recycled diatomaceous earth, obtained from a beer purification process, as a green sorbent phase for the determination of bisphenol A (BPA), benzophenone (BzP), triclocarban (TCC), 4-methylbenzylidene camphor (4-MBC) and 2-ethylhexyl-p-methoxycinnamate (EHMC) in environmental water samples. TF-SPME was combined with a 96-well plate system allowing for high-throughput analysis due to the simultaneous extraction/desorption up to 96 samples. The proposed sorbent phase exhibited good stability in organic solvents, as well as satisfactory analytical performance...
December 15, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29137680/correction-to-development-of-molecular-confirmation-tools-for-swift-and-easy-rabies-diagnostics
#4
Kore Schlottau, Conrad M Freuling, Thomas Müller, Martin Beer, Bernd Hoffmann
After publication of the article [1], it has been brought to our attention that an incorrect genetic sequence has been cited. On page 4, paragraph 1 the following sequence is cited "ATG GAT GCC GAC AAG ATT GTM TTY AAA GTY AAT A 3". This is an error and the correct sequence should be "GGG GGC TTT YCC TAG GGT KAT ACW GGG CTT T 3".
November 14, 2017: Virology Journal
https://www.readbyqxmd.com/read/29131388/saccharomyces-interspecies-hybrids-as-model-organisms-for-studying-yeast-adaptation-to-stressful-environments
#5
Ksenija Lopandic
The strong development of molecular biology techniques and next-generation sequencing technologies in the last two decades has significantly improved our understanding of the evolutionary history of Saccharomyces yeasts. It has been shown that many strains isolated from man-made environments are not pure genetic lines, but contain genetic materials from different species that substantially increase their genome complexity. A number of strains have been described as interspecies hybrids, implying different yeast species that under specific circumstances exchange and recombine their genomes...
November 13, 2017: Yeast
https://www.readbyqxmd.com/read/29129239/an-iso-%C3%AE-acid-rich-extract-from-hops-humulus-lupulus-attenuates-acute-alcohol-induced-liver-steatosis-in-mice
#6
Marianne Hege, Finn Jung, Cathrin Sellmann, Chengjun Jin, Doreen Ziegenhardt, Claus Hellerbrand, Ina Bergheim
OBJECTIVE: Results of in vitro and in vivo studies suggest that consumption of beer is less harmful for the liver than consumption of spirits. It also has been suggested that secondary plant compounds derived from hops such as xanthohumol or iso-α-acids may have beneficial effects on the development of liver diseases of various etiologies. The aim of this study was to determine whether iso-α-acids consumed in doses achieved by "normal" beer consumption have beneficial effects on health...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29129062/kinetic-models-for-the-role-of-protein-thiols-during-oxidation-in-beer
#7
Mogens L L Andersen, Matheo Gundermann, Bente P Danielsen, Marianne N Lund
Thiol-containing proteins have been suggested to have antioxidative properties in beer. A kinetic model has been setup for the reactivity of thiols during early stages of oxidative degradation of beer. Kinetic analysis based on the proposed reaction mechanism allowed evaluation of the relative reactivity of beer components, such as bitter acids from hops and polyphenols. The rate constants for the reaction of 1-hydroxyethyl radicals, which are generated during radical mediated oxidation of ethanol in beer, with hop bitter acids and thiols were very similar, and the concentration of the compounds in beer is therefore essential for the relative reactivity...
November 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29128999/impact-of-potentially-inappropriate-medications-and-polypharmacy-on-3-month-readmission-among-older-patients-discharged-from-acute-care-hospital-a-prospective-study
#8
Paolo Fabbietti, Giuseppina Di Stefano, Raffaella Moresi, Laura Cassetta, Mirko Di Rosa, Filippo Fimognari, Valentina Bambara, Giovanni Ruotolo, Alberto Castagna, Carmen Ruberto, Fabrizia Lattanzio, Andrea Corsonello
BACKGROUND: Polypharmacy and potentially inappropriate medications (PIMs) are known to affect several negative outcomes in older patients. However, studies comparatively assessing polypharmacy and PIMs in relation to readmission are distinctively lacking. AIMS: To compare the impact of polypharmacy and PIMs on 3-month readmission among older patients discharged from acute care hospital. METHODS: Our series consisted of 647 patients consecutively enrolled in a multicenter observational study...
November 11, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29126241/lactobacillus-backii-and-pediococcus-damnosus-isolated-from-170-year-old-beer-recovered-from-a-shipwreck-lack-the-metabolic-activities-required-to-grow-in-modern-lager-beer
#9
Ilkka Kajala, Jordyn Bergsveinson, Vanessa Friesen, Anna Redekop, Riikka Juvonen, Erna Storgårds, Barry Ziola
In 2010, bottles of beer containing viable bacteria of the common beer-spoilage species Lactobacillus backii and Pediococcus damnosus were recovered from a shipwreck near the Åland Islands, Finland. The 170-year quiescent state maintained by the shipwreck bacteria presented a unique opportunity to study lactic acid bacteria (LAB) evolution vis a vis growth and survival in the beer environment. Three shipwreck bacteria (one L. backii strain and two P. damnosus strains) and modern-day beer-spoilage isolates of the same two species were genome sequenced, characterized for hop iso-α-acid tolerance, and growth in degassed lager and wheat beer...
November 8, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29126210/the-functional-role-of-ventral-anterior-cingulate-cortex-in-social-evaluation-disentangling-valence-from-subjectively-rewarding-opportunities
#10
Anastasia E Rigney, Jessica E Koski, Jennifer S Beer
Despite robust associations between the ventral anterior cingulate cortex (vACC) and social evaluation, the role of vACC in social evaluation remains poorly understood. Two hypotheses have emerged from existing research: detection of positive valence and detection of opportunities for subjective reward. It has been difficult to understand whether one or both hypotheses are supported because previous research conflated positive valence with subjective reward. Therefore, the current fMRI study drew on a social evaluation paradigm that disentangled positive valence and subjective reward...
November 6, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29125921/management-of-anticoagulation-in-patients-with-prostate-cancer-receiving-enzalutamide
#11
Joseph J Shatzel, Molly M Daughety, Sven R Olson, Tomasz M Beer, Thomas G DeLoughery
Enzalutamide, a novel, oral androgen receptor antagonist used for the treatment of metastatic, castration-resistant prostate cancer, has been shown to improve overall and progression-free survival, prolong time to initiation of chemotherapy, reduce skeletal-related events, and carry a favorable adverse effect profile. Metastatic prostate cancer is a disease of older men, a population with an increased incidence of medical comorbidities warranting anticoagulation. Prostate cancer itself, along with some of its therapies, is also prothrombotic...
November 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29124905/rapid-and-simple-detection-of-foot-and-mouth-disease-virus-evaluation-of-a-cartridge-based-molecular-detection-system-for-use-in-basic-laboratories
#12
K V Goller, V Dill, M Madi, P Martin, Y Van der Stede, V Vandenberge, B Haas, S Van Borm, F Koenen, C J Kasanga, N Ndusilo, M Beer, L Liu, V Mioulet, B Armson, D P King, V L Fowler
Highly contagious transboundary animal diseases such as foot-and-mouth disease (FMD) are major threats to the productivity of farm animals. To limit the impact of outbreaks and to take efficient steps towards a timely control and eradication of the disease, rapid and reliable diagnostic systems are of utmost importance. Confirmatory diagnostic assays are typically performed by experienced operators in specialized laboratories, and access to this capability is often limited in the developing countries with the highest disease burden...
November 9, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29124579/-what-can-peat-therapy-achieve
#13
REVIEW
André-Michael Beer, Jürgen Kleinschmidt
No abstract text is available yet for this article.
November 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/29124367/saccharomyces-cerevisiae-proteinase-a-excretion-and-wine-making
#14
REVIEW
Lulu Song, Yefu Chen, Yongjing Du, Xibin Wang, Xuewu Guo, Jian Dong, Dongguang Xiao
Proteinase A (PrA), the major protease in Saccharomyces cerevisiae, plays an essential role in zymogen activation, sporulation, and other physiological processes in vivo. The extracellular secretion of PrA often occurs during alcoholic fermentation, especially in the later stages when the yeast cells are under stress conditions, and affects the quality and safety of fermented products. Thus, the mechanism underlying PrA excretion must be explored to improve the quality and safety of fermented products. This paper briefly introduces the structure and physiological function of PrA...
November 9, 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29123645/beerdecoded-the-open-beer-metagenome-project
#15
Jonathan Sobel, Luc Henry, Nicolas Rotman, Gianpaolo Rando
Next generation sequencing has radically changed research in the life sciences, in both academic and corporate laboratories. The potential impact is tremendous, yet a majority of citizens have little or no understanding of the technological and ethical aspects of this widespread adoption. We designed BeerDeCoded as a pretext to discuss the societal issues related to genomic and metagenomic data with fellow citizens, while advancing scientific knowledge of the most popular beverage of all. In the spirit of citizen science, sample collection and DNA extraction were carried out with the participation of non-scientists in the community laboratory of Hackuarium, a not-for-profit organisation that supports unconventional research and promotes the public understanding of science...
2017: F1000Research
https://www.readbyqxmd.com/read/29119690/experimental-infection-of-sheep-goats-and-cattle-with-a-bluetongue-virus-serotype-4-field-strain-from-bulgaria-2014
#16
C Schulz, C Sailleau, E Bréard, J Flannery, C Viarouge, S Zientara, M Beer, C Batten, B Hoffmann
In 2014, a new bluetongue virus serotype 4 (BTV-4) strain was detected in southern Greece and spread rapidly throughout the Balkan Peninsula and adjacent countries. Within half a year, more than 7,068 outbreaks were reported in ruminants, particularly in sheep. However, the reported morbidity and case fatality rates in ruminants varied. The pathogenesis of a Bulgarian BTV-4 strain isolated from sheep during the BTV-4 epizootic was studied in different species. Therefore, four sheep, three goats and three cattle were experimentally infected with the isolate BTV-4/BUL2014/15 and monitored for clinical signs up to several weeks...
November 8, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29119486/potentially-harmful-medication-use-and-decline-in-health-related-quality-of-life-among-community-dwelling-older-adults
#17
Kenya Ie, Eric Chou, Richard D Boyce, Steven M Albert
BACKGROUND: Several scales to quantify the impact of potentially harmful medications (PHMs) have been shown to predict mortality and functional decline; however, the effect of PHMs on quality of life (QoL) has not been well-studied. OBJECTIVE: The aims of this study were to investigate an association between PHM use and change in health-related QoL among community-dwelling older adults, and to compare the predictive capacity of PHM scales. METHODS: We conducted a retrospective cohort study using prescription claims data and survey responses...
December 2017: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29116352/a-multiplex-competitive-elisa-for-the-detection-and-characterization-of-gluten-in-fermented-hydrolyzed-foods
#18
Rakhi Panda, Marc Boyer, Eric A E Garber
A novel competitive ELISA was developed utilizing the G12, R5, 2D4, MIoBS, and Skerritt antibody-HRP conjugates employed in nine commercial ELISA test kits that are routinely used for gluten detection. This novel multiplex competitive ELISA simultaneously measures gliadin-, deamidated gliadin-, and glutenin-specific epitopes. The assay was used to evaluate 20 wheat beers, 20 barley beers, 6 barley beers processed to reduce gluten, 15 soy sauces, 6 teriyaki sauces, 6 Worcestershire sauces, 6 vinegars, and 8 sourdough breads...
November 7, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29114899/in-reference-to-intervention-for-elevated-intracranial-pressure-improves-success-rate-after-repair-of-spontaneous-cerebrospinal-fluid-leaks
#19
João Mangussi-Gomes, Leonardo L Balsalobre, Marcos Q T Gomes, Eduardo A S Vellutini, Aldo E C Stamm, André Beer-Furlan
No abstract text is available yet for this article.
November 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29114061/mental-health-screening-quality-improvement-learning-collaborative-in-pediatric-primary-care
#20
Lee S Beers, Leandra Godoy, Tamara John, Melissa Long, Matthew G Biel, Bruno Anthony, Laura Mlynarski, Rachel Moon, Mark Weissman
BACKGROUND: In the United States, up to 20% of children experience a mental health (MH) disorder in a given year, many of whom remain untreated. Routine screening during annual well visits is 1 strategy providers can use to identify concerns early and facilitate appropriate intervention. However, many barriers exist to the effective implementation of such screening. METHODS: A 15-month quality improvement learning collaborative was designed and implemented to improve screening practices in primary care...
November 7, 2017: Pediatrics
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