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Snježana Herceg Romanić, Gordana Vuković, Darija Klinčić, Marijana Matek Sarić, Ivan Župan, Davor Antanasijević, Aleksandar Popović
To tackle the ever-present global concern regarding human exposure to persistent organic pollutants (POPs) via food products, this study strived to indicate associations between organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in lake-fish tissue depending on the species and sampling season. Apart from the monitoring initiatives recommended in the Global Monitoring Plan for POPs, the study discussed 7 OCPs and 18 PCB congeners determined in three Cyprinidae species (rudd, carp, and Prussian carp) from Vransko Lake (Croatia), which are widely domesticated and reared as food fish across Europe and Asia...
May 18, 2018: Environmental Research
Manuel Mendoza-Carranza, Elisabet Ejarque, Leopold A J Nagelkerke
Tropical small-scale fisheries are typical for providing complex multivariate data, due to their diversity in fishing techniques and highly diverse species composition. In this paper we used for the first time a supervised Self-Organizing Map (xyf-SOM), to recognize and understand the internal heterogeneity of a tropical marine small-scale fishery, using as model the fishery fleet of San Pedro port, Tabasco, Mexico. We used multivariate data from commercial logbooks, including the following four factors: fish species (47), gear types (bottom longline, vertical line+shark longline and vertical line), season (cold, warm), and inter-annual variation (2007-2012)...
2018: PloS One
Srinivasa Rao Mutheneni, Rajasekhar Mopuri, Suchithra Naish, Deepak Gunti, Suryanarayana Murty Upadhyayula
Background and objectives: Dengue is an emerging and re-emerging infectious disease, transmitted by mosquitoes. It is mostly prevalent in tropical and sub-tropical regions of the world, particularly, in Asia-Pacific region. To understand the epidemiology and spatial distribution of dengue, a retrospective surveillance study was conducted in the state of Andhra Pradesh, India during 2011-2013. Material and methods: District-wise disease endemicity levels were mapped through geographical information system (GIS) tools...
February 2018: Parasite Epidemiology and Control
Linnea Linde-Krieger, Tuppett M Yates
This investigation evaluated a theoretically specified model of associations among mothers' history of child sexual abuse (CSA), a helpless state of mind (SOM) with regard to the mother-child relationship, and increased behavior problems in the next generation. Moreover, we evaluated the moderating influence of child gender on predicted relations between mothers' CSA severity and helpless SOM (i.e., moderated mediation). Participants were 225 biological mother-preschooler dyads (48% female; 46.4% Latinx) drawn from an ongoing, longitudinal study of representation and regulation in child development...
January 1, 2018: Child Maltreatment
Carlos Dafonte, Daniel Garabato, Marco A Álvarez, Minia Manteiga
Analyzing huge amounts of data becomes essential in the era of Big Data, where databases are populated with hundreds of Gigabytes that must be processed to extract knowledge. Hence, classical algorithms must be adapted towards distributed computing methodologies that leverage the underlying computational power of these platforms. Here, a parallel, scalable, and optimized design for self-organized maps (SOM) is proposed in order to analyze massive data gathered by the spectrophotometric sensor of the European Space Agency (ESA) Gaia spacecraft, although it could be extrapolated to other domains...
May 3, 2018: Sensors
Gautier Landrot, Saengdao Khaokaew
Lead (Pb) stabilization in polluted soils treated by a Pb immobilization technique may be dependent on the speciation of Pb present in specific particle-size fractions of the soil. However, the scale-dependency of Pb speciation in contaminated soils is still not clearly understood. In this study, the natures and amounts of Pb chemical forms were determined in five Pb-polluted soil samples from Klity Village, Thailand, and their particle-size fractions. This was achieved using multiple analytical tools, including bulk Extended X-ray Absorption Fine Structure (EXAFS) spectroscopy at the Pb LIII edge...
May 11, 2018: Environmental Science & Technology
Lingyu Li, Jinxia Xue, Xiangqian He, Sheng Zhang, Chu Fan
Skin aging is the most intuitive and obvious sign of the human aging processes. Qualitative and quantitative determination of skin aging is of particular importance for the evaluation of human aging and anti-aging treatment effects. To solve the problem of subjectivity of conventional skin aging grading methods, the self-organizing map (SOM) network was used to explore an automatic method for skin aging grading. First, the ventral forearm skin images were obtained by a portable digital microscope and two texture parameters, i...
June 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
Islam Muhammad Shariful, Nakako Katsuno, Takahisa Nishizu
Kinetic analysis was used to study the destabilization of mayonnaise by focusing on the fat crystals. Mayonnaise prepared from rapeseed oil and soybean oil was stored at temperatures ranging from −20 to −40 °C. The destabilization kinetic parameters were measured by observing oil separation over time. The destabilization rate constant, kd , increased with decreasing temperature. The highest value of kd was 1.28 × 10−3 min−1 at −40 °C for rapeseed oil mayonnaise (RoM) and the lowest was 1...
May 8, 2018: Foods (Basel, Switzerland)
Jan Robert Grøndahl, Øystein Fossdal, Torgeir Hauge-Iversen, Einar Husebye, Elin Olaug Rosvold, Trygve Kongshavn
BAKGRUNN: Hensikten med denne studien var å kartlegge grunnlaget for innleggelser ved en stor medisinsk avdeling i Norge. Vi har vurdert mulige alternativer til innleggelse og hvorvidt triagering kan bidra til å identifisere aktuelle pasienter. MATERIALE OG METODE: Alle innleggelser ved Medisinsk avdeling ved Drammen sykehus i en full uke høsten 2014 ble registrert med pasientens alder, kjønn, liggetid, innleggende lege/instans, hvor vedkommende ble innlagt fra og diagnose ved innleggelse og utskrivning...
May 8, 2018: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Christelle Anaclet, Roberto De Luca, Anne Venner, Olga Malyshevskaya, Michael Lazarus, Elda Arrigoni, Patrick M Fuller
Recent studies have identified an especially important role for basal forebrain GABAergic (BFVGAT ) neurons in the regulation of behavioral waking and fast cortical rhythms associated with cognition. However, BFVGAT neurons comprise several neurochemically and anatomically distinct sub-populations, including parvalbumin- and somatostatin-containing BFVGAT neurons (BFParv and BFSOM ), and it was recently reported that optogenetic activation of BFSOM neurons increases the probability of a wakefulness to non-rapid-eye movement (NREM) sleep transition when stimulated during the animal's rest period...
May 7, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Kun Li, Huanxiang Yang, Xu Han, Lingyu Xue, Yang Lv, Jinhua Li, Zhanyong Fu, Chuanrong Li, Weixing Shen, Huiling Guo, Yikun Zhang
To study the fractal dimensions of the soil particle size distributions (PSDs) within different plantations (of Pinus densiflora, Quercus acutissima, Robinia pseudoacacia, and Larix kaempferi) and evaluate PSDs as an indicator of the likelihood of Robinia pseudoacacia invasion, the soil porosity of 0-20 cm soil layers was measured at different plantations in the Yaoxiang Forest Farm, Shandong Province, China. The results showed that the fractal dimension (Dm ) values varied from 2.59 to 2.70 among the different plantations and were significantly negatively correlated to sand content and positively correlated to silt content and clay content...
May 4, 2018: Scientific Reports
Harri Niska, Ari Serkkola
Extensive monitoring data on waste generation is increasingly collected in order to implement cost-efficient and sustainable waste management operations. In addition, geospatial data from different registries of the society are opening for free usage. Novel data analytics approaches can be built on the top of the data to produce more detailed, and in-time waste generation information for the basis of waste management and collection. In this paper, a data-based approach based on the self-organizing map (SOM) and the k-means algorithm is developed for creating a set of waste generation type profiles...
April 30, 2018: Waste Management
Guanxiao Chang, Chuntao Wang, Xiangxiang Kong, Qian Chen, Yongping Yang, Xiangyang Hu
Imbibed seeds monitor environmental and endogenous signals to break dormancy and initiate growth under appropriate conditions. In Arabidopsis thaliana, high temperature (HT) induces secondary seed dormancy, but the underlying mechanism remains unclear. In this study, we found that the abi5-1 mutant was insensitive to high temperature, whereas plants overexpressing ABI5 displayed sensitivity. We then identified ABA-insensitive five-binding protein 2 (AFP2), which interacts with ABI5 and is involved in HT-induced secondary seed dormancy...
April 30, 2018: Biochemical and Biophysical Research Communications
Ema Yoshioka, Vipin Shankar Chelakkot, Maria Licursi, Suzette G Rutihinda, Jayoti Som, Leena Derwish, Justin J King, Theerawat Pongnopparat, Karen Mearow, Mani Larijani, Ann M Dorward, Kensuke Hirasawa
Protoporphyrin IX (PpIX) is an endogenous fluorescent molecule that selectively accumulates in cancer cells treated with the heme precursor 5-aminolevulinic acid (5-ALA). This cancer-specific accumulation of PpIX is used to distinguish tumor from normal tissues in fluorescence-guided surgery (FGS) and to destroy cancer cells by photodynamic therapy (PDT). In this study, we demonstrate that oncogenic Ras/mitogen-activated protein kinase kinase (MEK) pathway can modulate PpIX accumulation in cancer cells. Methods: To identify Ras downstream elements involved in PpIX accumulation, chemical inhibitors were used...
2018: Theranostics
Roger Estrada-Tejedor, Gerhard F Ecker
ATP binding cassette (ABC) transporters play a pivotal role in drug elimination, particularly on several types of cancer in which these proteins are overexpressed. Due to their promiscuous ligand recognition, building computational models for substrate classification is quite challenging. This study evaluates the use of modified Self-Organizing Maps (SOM) for predicting drug resistance associated with P-gp, MPR1 and BCRP activity. Herein, we present a novel multi-labelled unsupervised classification model which combines a new clustering algorithm with SOM...
May 1, 2018: Scientific Reports
Jin Li, Min Zhang, Danshi Wang, Shaojun Wu, Yueying Zhan
A novel joint atmospheric turbulence (AT) detection and adaptive demodulation technique based on convolutional neural network (CNN) are proposed for the OAM-based free-space optical (FSO) communication. The AT detecting accuracy (ATDA) and the adaptive demodulating accuracy (ADA) of the 4-OAM, 8-OAM, 16-OAM FSO communication systems over computer-simulated 1000-m turbulent channels with 4, 6, 10 kinds of classic ATs are investigated, respectively. Compared to previous approaches using the self-organizing mapping (SOM), deep neural network (DNN) and other CNNs, the proposed CNN achieves the highest ATDA and ADA due to the advanced multi-layer representation learning without feature extractors designed carefully by numerous experts...
April 16, 2018: Optics Express
Jongkwan Park, Kyung Hwa Cho, Eunkyung Lee, Sungyun Lee, Jaeweon Cho
There is a growing interest in the removal of pharmaceuticals from wastewater because pharmaceuticals have potential ecotoxicological effects. Among several removal mechanisms, the sorption of pharmaceuticals to sediment organic matter is an important mechanism related to the mobility of pharmaceuticals. This study investigated the sorption of pharmaceuticals to soil organic matter (SOM) by electrostatic interactions. SOM located on the surface of soil/sediment generally has a negative charge because of the functional groups present (i...
April 23, 2018: Science of the Total Environment
Kiyoumars Roushangar, Farhad Alizadeh, Jan Adamowski
Understanding precipitation on a regional basis is an important component of water resources planning and management. The present study outlines a methodology based on continuous wavelet transform (CWT) and multiscale entropy (CWME), combined with self-organizing map (SOM) and k-means clustering techniques, to measure and analyze the complexity of precipitation. Historical monthly precipitation data from 1960 to 2010 at 31 rain gauges across Iran were preprocessed by CWT. The multi-resolution CWT approach segregated the major features of the original precipitation series by unfolding the structure of the time series which was often ambiguous...
April 27, 2018: Environmental Research
Quynh-Anh Nguyen, Roger A Nicoll
While the canonical assembly of a GABAA receptor contains two α subunits, two β subunits, and a fifth subunit, it is unclear which variants of each subunit are necessary for native receptors. We used CRISPR/Cas9 to dissect the role of the GABAA receptor β subunits in inhibitory transmission onto hippocampal CA1 pyramidal cells and found that deletion of all β subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of β3, alone or in combination with another β subunit, impaired inhibitory synaptic transmission...
May 16, 2018: Neuron
Xin Yan, Hui An
The variation of soil properties, the fractal dimension of soil particle size, and the relationships between fractal dimension of soil particle size and soil properties in the process of desertification in desert grassland of Ningxia were discussed. The results showed that the fractal dimension (D) at different desertification stages in desert grassland varied greatly, the value of D was between 1.69 and 2.62. Except for the 10-20 cm soil layer, the value of D gradually declined with increa sing desertification of desert grassland at 0-30 cm soil layer...
October 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
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