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TASS syndrome

Serpil Yazgan, Ugur Celik, Orhan Ayar, Suat Hayri Ugurbas, Burcu Celik, Mehmet Orçun Akdemir, Silay Canturk Ugurbas, Atilla Alpay
PURPOSE: To compare the systemic and ocular characteristics and laboratory findings of patients developing toxic anterior segment syndrome (TASS) after uneventful phaco surgery with unaffected subjects undergoing the same surgery in the same session. DESIGN: A retrospective case-control study. METHODS: The study group consisted of 26 eyes of 26 patients who underwent uneventful phaco surgery and who went on to develop TASS, while the control group included 39 subjects who had routine phaco surgery in the same session by the same surgeon...
January 27, 2017: International Ophthalmology
Tetsuro Oshika, Shuichiro Eguchi, Hiroshi Goto, Yuichi Ohashi
PURPOSE: To report the results of a clinical investigation after an outbreak of subacute-onset toxic anterior segment syndrome (TASS) after implantation of single-piece acrylic intraocular lenses (IOLs), which then were recalled voluntarily from the market. DESIGN: Retrospective, multicenter, observational case series. PARTICIPANTS: Cases reported to the manufacturer from January 2015 through March 2016 of unusual ocular inflammation after cataract surgery using AcrySof ReSTOR, ReSTOR toric, or AcrySof IQ toric SN6AT6-9 IOLs (Alcon Laboratories, Inc...
January 19, 2017: Ophthalmology
Neslihan Sevimli, Remzi Karadag, Ozgur Cakici, Huseyin Bayramlar, Seydi Okumus, Unsal Sari
We present the case of a 31-year-old patient with toxic anterior segment syndrome (TASS) that developed after undergoing deep anterior lamellar keratoplasty (DALK). She had keratoconus, and despite wearing hard contact lenses for many years in the left eye, her vision had deteriorated; therefore, DALK was performed on this eye. The preoperative visual acuity (VA) was finger counting at 3 m. Routine DALK was performed using the "big-bubble" technique. The corneal entry incision was hydrated at the end of the surgery, which was terminated by air injection into the anterior chamber...
September 2016: Arquivos Brasileiros de Oftalmologia
Andrew L Sorenson, Robert L Sorenson, David J Evans
PURPOSE: To identify etiology of toxic anterior segment syndrome (TASS) after uneventful phacoemulsification. SETTING: EyeMD Laser and Surgery Center, Oakland, California. DESIGN: Retrospective case series. METHODS: Patient charts with TASS were reviewed. Reservoirs of 2 autoclaves associated with these cases were cultured for bacterial contamination. Cultures were performed on 23 other autoclave reservoirs at surgery centers in the local area...
November 2016: Journal of Cataract and Refractive Surgery
Manpreet Kaur, Jeewan S Titiyal, Ruchita Falera, Tarun Arora, Namrata Sharma
PURPOSE: To evaluate the visual and anatomical outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with toxic anterior segment syndrome (TASS). METHODS: Fourteen eyes of 14 patients who underwent clear corneal DSAEK for endothelial decompensation secondary to TASS after phacoemulsification were included in this prospective study. Intraoperative surgical difficulties were noted. Preoperative and postoperative evaluation of visual acuity, slit-lamp examination, intraocular pressure, central corneal thickness, and endothelial count was performed in all cases...
January 2017: Cornea
Tamer Tandogan, Ramin Khoramnia, Gerd Uwe Auffarth, Michael Janusz Koss, Chul Young Choi
Purpose. To investigate the role of indocyanine green (ICG) dye as a causative material of toxic anterior segment syndrome (TASS) in an experimental rabbit model. Method. Eight eyes of four rabbits were allocated to this study. Capsular staining was performed using ICG dye, after which the anterior chamber was irrigated with a balanced salt solution. The effects of different concentrations (control, 0.25, 0.5, and 1.0%), exposure times (10 and 60 seconds), and the degree of dissolution (differently vortexed) were investigated...
2016: Journal of Ophthalmology
Talal Abdulrahman Althomali
CONTEXT: Toxic Anterior Segment Syndrome (TASS) is an acute postoperative inflammatory reaction in which a noninfectious substance enters the anterior segment and induces toxic damage to the intraocular tissues. OBJECTIVE: To present etiologic investigation of two consecutive clusters of TASS. TASS outbreak and investigation: This paper presents two consecutive clusters of TASS in 15 of the 24 uneventful surgeries and the investigation carried out to find the etiology...
September 2016: Cutaneous and Ocular Toxicology
Burçin Çakır, Erkan Celik, Nilgün Özkan Aksoy, Özlem Bursalı, Turgay Uçak, Erdinç Bozkurt, Gursoy Alagoz
PURPOSE: To report toxic anterior segment syndrome (TASS) after cataract surgery possibly associated with intracameral use of cefuroxime. METHODS: We conducted a retrospective chart review and analysis on the pre- and postoperative conditions of the subjects who had developed TASS. RESULTS: The patient group consisted of 17 patients. Tyndallization and fibrin fibers were positive in all eyes. In four eyes, hypopyon formation developed. These reactions diminished on the third day and fully resolved 1 week after the operations with the use of intensive topical steroid and mydriatic therapy...
2015: Clinical Ophthalmology
Nir Sorkin, Dafna Goldenberg, Amir Rosenblatt, Gabi Shemesh
PURPOSE: To evaluate changes in choroidal, retinal, and nerve fiber layer (NFL) thickness following toxic anterior segment syndrome (TASS). METHODS: Macular and peripapillary choroidal thickness was measured using enhanced depth imaging (EDI) optical coherence tomography (OCT) on the day of the diagnosis and on three follow-up exams (months 1 to 4). A similar OCT analysis of central retinal and NFL thickness was performed. RESULTS: Thirteen TASS patients were included...
March 2015: Graefe's Archive for Clinical and Experimental Ophthalmology
Servet Cetinkaya, Zeynep Dadaci, Hüsamettin Aksoy, Nursen Oncel Acir, Halil Ibrahim Yener, Ekrem Kadioglu
PURPOSE: To evaluate the clinical findings and courses of five patients who developed toxic anterior-segment syndrome (TASS) after cataract surgery and investigate the cause. MATERIALS AND METHODS: In May 2010, on the same day, ten patients were operated on by the same surgeon. Five of these patients developed TASS postoperatively. RESULTS: Patients had blurred-vision complaints on the first day after the operation, but no pain. They had different degrees of diffuse corneal edema, anterior-chamber reaction, fibrin, hypopyon, iris atrophies, and dilated pupils...
2014: Clinical Ophthalmology
Su-Na Lee
Toxic anterior segment syndrome (TASS) is an acute sterile postoperative anterior segment inflammation that may occur after anterior segment surgery. I report herein a case that developed mild TASS in one eye after bilateral uneventful cataract surgery, which was masked during early postoperative period under steroid eye drop and mimicking delayed onset TASS after switching to weaker steroid eye drop.
August 2014: Indian Journal of Ophthalmology
Modi Naftali, Ina Movshovitz, Haneen Jabaly
INTRODUCTION: Cataract surgery is one of the most common surgeries in medicine. Re-evaluating the regimen for followup might save thousands of visits to the clinic and many working days every year. PURPOSE: To check the safety of same day postoperative follow-up as a substitute for the common practice in Israel of examination on the next day. METHODS: Retrospective examination of the digital files of patients after cataract surgery, who had their first postoperative examination on the same day of the surgery and the second examination after 1 week, during 2 years in a private clinic...
July 2014: Harefuah
Youngsub Eom, Dong Yeol Lee, Bo-Ram Kang, Jeong-Hwa Heo, Kyung-Ho Shin, Hyo Myung Kim, Jong Suk Song
PURPOSE: To compare clinical findings and the aqueous levels of inflammatory mediators between toxic anterior segment syndrome (TASS) and endotoxin-induced uveitis (EIU) animal models and to evaluate the efficacy of systemic steroid pretreatment in both animal models. METHODS: Rats were used in this study. Ortho-phthalaldehyde solution was injected into the anterior chamber to produce TASS (n=30), and lipopolysaccharide was injected into one hind footpad to produce EIU (n=30)...
October 2014: Investigative Ophthalmology & Visual Science
F Valour, J Tasse, S Trouillet-Assant, J-P Rasigade, B Lamy, E Chanard, P Verhoeven, J-W Decousser, H Marchandin, M Bès, C Chidiac, F Vandenesch, T Ferry, F Laurent
The prevalence of clonal complex (CC) 398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.
October 2014: Clinical Microbiology and Infection
Claudio Straccia, Marc J Tassé, Paolo Ghisletta, Koviljka Barisnikov
The main aims of the present study were to examine the factor structure and the internal consistency of the factors in the French version of the Reiss Screen of Maladaptive Behavior in a French-speaking European sample. The prevalence of psychopathology and the influence of associated factors were also examined. The Reiss Screen was administered to 467 adults (age range: 18-73) with intellectual disability living in the French-speaking regions of Switzerland and Belgium. A confirmatory factor analysis was performed to replicate the original factor structure...
November 2013: Research in Developmental Disabilities
Osman Sevki Arslan, Zeki Tunc, Didar Ucar, Ismail Seckin, Erdogan Cicik, Hande Kalem, Sadik Sencan, Mustafa Hepokur
PURPOSE: To report the histologic findings of penetrating keratoplasty buttons in decompensated corneas with toxic anterior segment syndrome (TASS) after a cataract surgery is performed. METHODS: We evaluated the histologic findings of 16 corneal buttons of 16 patients who exhibited decompensation findings because of TASS by means of light microscopy. The patients were classified into 3 groups: The first group consisted of 5 corneal buttons with mild symptoms in which the central corneal thicknesses (CCTs) were ≤650 μm, and the visual acuities (VAs) were ≥0...
October 2013: Cornea
Noor Bakht Nizamani, Imran Ahmed Bhutto, Khalid Iqbal Talpur
PURPOSE: To report the largest cluster of Urrets-Zavalia Syndrome (UZS), which occurred as a sequel of toxic anterior segment syndrome (TASS) after uneventful cataract surgery, and to evaluate the possible causes and risk factors to prevent additional cases. SETTING: Department of Ophthalmology, Liaquat University of Medical & Health Sciences, Hyderabad, Pakistan. DESIGN: Prospective Case Series. METHODS: 15 consecutive TASS cases following uneventful cataract surgery were evaluated for potential causes and risk factors...
August 2013: British Journal of Ophthalmology
Nir Sorkin, David Varssano
PURPOSE: To present a unique case of a 58-year-old female with toxic anterior segment syndrome (TASS), following a triple procedure: Descemet's stripping automated endothelial keratoplasty (DSAEK), phacoemulsification and posterior chamber intraocular lens implantation. METHODS: The patient was treated with topical dexamethasone sodium phosphate 0.1% and topical atropine sulfate 1%. Due to a slow improvement in her clinical status, oral prednisone 1 mg/kg/day was added...
September 2012: Case Reports in Ophthalmology
Wendy Moyle, Robert D Yee, John K Burns, Tim Biggins
PURPOSE: To present clinical findings and etiologic investigation of two consecutive clusters of toxic anterior segment syndrome (TASS) after uncomplicated phacoemulsification cataract surgery. CASE REPORT: At the Veterans Affairs Northern Indiana Health Care System Fort Wayne campus, 11 consecutive patients on two separate days in 2011 underwent clear corneal incision phacoemulsification cataract surgery by the same surgeon. On the first postoperative day, all patients had 1+ to 2+ diffuse limbus to limbus stromal edema and 2+ to 4+ anterior chamber white blood cells...
January 2013: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Manoharan Shunmugam, Charles E Hugkulstone, Roger Wong, Tom H Williamson
Toxic anterior segment syndrome (TASS), though rare, has been well documented following anterior segment surgery but not following vitrectomy (Monson et al., J Cataract Refract Surg 18:184-189, 1992). It typically presents within 24 h of uncomplicated cataract surgery with minimal or no pain and intense anterior segment inflammation (Monson et al. 1992). Various exogenous chemicals have been identified as the cause of TASS (Kutty et al., Cataract Refract Surg, 34:585-590 2008; Liu et al., J Cataract Refract Surg 27:1746-1750, 2001)...
June 2013: International Ophthalmology
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