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https://www.readbyqxmd.com/read/28731934/long-term-evaluation-of-specular-microscopic-changes-following-nd-yag-iridotomy-in-chronic-primary-angle-closure-glaucoma-eyes
#1
Ramanjit Sihota, Esha Agarwal, Mathew James, Meena Verma, Lalit Kumar, Tanuj Dada, Viney Gupta, Kulwant Singh Kapoor
AIM: The aim of this study was to evaluate specular microscopy of chronic primary angle-closure glaucoma (CPACG) eyes at least 1 year after Nd:YAG iridotomy, and compare them with CPACG eyes without an iridotomy and age-matched, normal eyes. PATIENTS AND METHOD: Consecutive patients of CPACG at the Glaucoma service were screened. All patients underwent slit-lamp biomicroscopy, +90 D examination, and applanation tonometry. A total of 100 eyes of 100 consecutive patients of CPACG with an Nd:YAG iridotomy performed ≥1 year before, who met all inclusion/exclusion criteria, 60 consecutive CPACG eyes without an iridotomy, and 60 age and refraction-matched control eyes were enrolled...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28718823/surface-chemistry-interactions-of-cationorm-with-films-by-human-meibum-and-tear-film-compounds
#2
Georgi As Georgiev, Norihiko Yokoi, Yana Nencheva, Nikola Peev, Philippe Daull
Cationorm(®) (CN) cationic nanoemulsion was demonstrated to enhance tear film (TF) stability in vivo possibly via effects on tear film lipid layer (TFLL). Therefore the interactions of CN with human meibum (MGS) and TFLL in vitro and in vivo deserve special study. MGS and CN were spread at the air/water interface of a Langmuir surface balance to ensure a range of MGS/CN oil phase ratios: 20/1, 10/1, 5/1, 3/1, 2/1 and 1/1. The films capability to reorganize during dynamic area changes was evaluated via the surface pressure-area compression isotherms and step/relaxation dilatational rheology studies...
July 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28714237/effects-of-intracameral-ascorbic-acid-on-the-corneal-endothelium-of-dogs-undergoing-phacoemulsification
#3
Ivan R M Padua, Gisele P Valdetaro, Tiago B Lima, Karina K Kobashigawa, Paloma E S Silva, Marcela Aldrovani, Pedro P M Padua, Jose L Laus
OBJECTIVE: Cataracts are the most common ocular disorder in dogs. Phacoemulsification is the preferred treatment method among ophthalmologists, but the cellularity of the endothelium must be considered for its success, as endothelial lesions may produce permanent corneal decompensation. The objective of this study was to evaluate the effects of intracameral ascorbic acid, a known antioxidant, on the corneal endothelium of dogs undergoing phacoemulsification. ANIMAL STUDIED: In all, 40 eyes from 20 dogs, males and females from 7 to 12 years of age, were assessed for mature cataracts...
July 17, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28699324/corneal-endothelial-cell-loss-and-corneal-biomechanical-characteristics-after-two-step-sequential-or-combined-phaco-vitrectomy-surgery-for-idiopathic-epiretinal-membrane
#4
Hassan Hamoudi, Ulrik Correll Christensen, Morten La Cour
PURPOSE: To assess the impact of sequential and combined surgery [cataract surgery and 23-gauge pars plana vitrectomy (PPV) with peeling] on corneal endothelium cell density (CED) and corneal biomechanical characteristics. METHODS: Phakic eyes with epiretinal membrane (ERM) were prospectively allocated to (i) cataract surgery and subsequent PPV (CAT group), (ii) PPV and subsequent cataract surgery (VIT group) or (iii) phacovitrectomy (COMBI group). Eyes were examined at baseline, 1 month after each surgery, and at 3 and 12 months follow-up...
August 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28696173/multimodal-imaging-in-anterior-uveitis
#5
Jay Siak, Padmamalini Mahendradas, Soon-Phaik Chee
Anterior uveitis is the most common group of uveitis worldwide, with a diverse spectrum ranging from autoimmune and infectious to masquerade etiologies. Elucidation of the underlying etiology may be challenging, but it remains important, especially for recurrent uveitis. Multimodal imaging has improved our understanding and management of many posterior uveitis and panuveitis. Similarly, a wide variety of anterior segment ophthalmic imaging techniques are available to allow the monitoring of the structural changes that may develop during anterior uveitis...
June 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28692574/technician-consistency-in-specular-microscopy-measurements-a-real-world-retrospective-analysis-of-a-united-states-eye-bank
#6
Gabriel M Rand, Ji Won Kwon, Patrick K Gore, Mitchell D McCartney, Roy S Chuck
PURPOSE: To quantify consistency of endothelial cell density (ECD) measurements among technicians in a single US eye bank operating under typical operating conditions. METHODS: In this retrospective analysis of 51 microscopy technicians using a semiautomated counting method on 35,067 eyes from July 2007 to May 2015, technician- and date-related marginal ECD effects were calculated using linear regression models. ECD variance was correlated with the number of specular microscopy technicians...
July 7, 2017: Cornea
https://www.readbyqxmd.com/read/28682792/performance-of-a-high-resolution-depth-encoding-pet-detector-using-barium-sulfate-reflector
#7
Zhonghua Kuang, Xiaohui Wang, Cheng Li, Xinhan Deng, Kai Feng, Zhanli Hu, Xin Fu, Ning Ren, Xianming Zhang, Yunfei Zheng, Dong Liang, Xin Liu, Hairong Zheng, Yongfeng Yang
Small animal positron emission tomography (PET) is a well-established imaging modality in preclinical biomedical research. The performance of current small animal PET scanners is mainly limited by the detector performance and depth-encoding detectors are required to simultaneously achieve high spatial resolution and high sensitivity. In this work, the performance of a high-resolution dual-ended readout lutetium-yttrium oxyorthosilicate (LYSO) array using barium sulfate powder (BaSO4) as the inter-crystal reflector was measured for the first time and compared to that of a LYSO array using the most commonly used enhanced specular reflector (ESR)...
July 6, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28677912/analysis-of-kera-in-four-families-with-cornea-plana-identifies-two-novel-mutations
#8
Lubica Dudakova, Jang Hee J Vercruyssen, Irina Balikova, Lavina Postolache, Bart P Leroy, Pavlina Skalicka, Petra Liskova
PURPOSE: To identify the molecular genetic cause in four families of various ethnic backgrounds with cornea plana. METHODS: Detailed ophthalmological examination and direct sequencing of the KERA coding region in five patients of Czech and Turkish origin and their available family members. RESULTS: Compound heterozygosity for a novel missense mutation c.209C>T; p.(Pro70Leu) and a novel splice site mutation c.887-1G>A in KERA were detected in two affected siblings of Czech origin...
July 5, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28674859/comparison-of-central-corneal-thickness-and-endothelial-cell-measurements-by-scheimpflug-camera-system-and-two-noncontact-specular-microscopes
#9
Irmak Karaca, Suzan Guven Yilmaz, Melis Palamar, Halil Ates
PURPOSE: To investigate the correlation of Scheimpflug camera system and two noncontact specular microscopes in terms of central corneal thickness (CCT) and corneal endothelial cell morphology measurements. METHODS: One hundred eyes of 50 healthy subjects were examined by Pentacam Scheimpflug Analyzer, CEM-530 (Nidek Co, Ltd, Gamagori, Japan) and CellChek XL (Konan Medical, California, USA) via fully automated image analysis with no corrections made. Measurement differences and agreement between instruments were determined by intraclass correlation analysis...
July 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28670843/poorly-differentiated-vaginal-adenocarcinoma-with-aggressive-behavior-pap-smear-findings
#10
José Eleutério, Francisca Margalene Medeiros de Freitas, Denise Nunes Oliveira, David Freitas Moreira, Mirley Sângela Pessoa
Vaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation...
July 3, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28664948/experimental-review-chemical-reduction-of-graphene-oxide-go-to-reduced-graphene-oxide-rgo-by-aqueous-chemistry
#11
L G Guex, B Sacchi, K F Peuvot, R L Andersson, A M Pourrahimi, V Ström, S Farris, R T Olsson
The electrical conductivity of reduced graphene oxide (rGO) obtained from graphene oxide (GO) using sodium borohydride (NaBH4) as a reducing agent has been investigated as a function of time (2 min to 24 h) and temperature (20 °C to 80 °C). Using a 300 mM aqueous NaBH4 solution at 80 °C, reduction of GO occurred to a large extent during the first 10 min, which yielded a conductivity increase of 5 orders of magnitude to 10 S m(-1). During the residual 1400 min of reaction, the reduction rate decreased significantly, eventually resulting in a rGO conductivity of 1500 S m(-1)...
July 13, 2017: Nanoscale
https://www.readbyqxmd.com/read/28663834/dermoscopy-guided-dark-field-multi-functional-optical-coherence-tomography
#12
Soonjae Kwon, Yeoreum Yoon, Bumju Kim, Won Hyuk Jang, Byungho Oh, Kee Yang Chung, Ki Hean Kim
Dermoscopy is a skin surface microscopic technique allowing specular reflection free observation of the skin, and has been used to examine pigmented skin lesions. However, dermoscopy has limitations in providing depth information due to lack of 3D resolution. In order to overcome the limitations, we developed dermoscopy guided multi-functional optical coherence tomography (MF-OCT) providing both high-contrast superficial information and depth-resolved structural, birefringent, and vascular information of the skin simultaneously...
March 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28655564/enhanced-limbic-impaired-cortical-loop-connection-onto-the-hippocampus-of-nhe-rats-application-of-resting-state-functional-connectivity-in-a-preclinical-adhd-model
#13
F Zoratto, G M Palombelli, L A Ruocco, E Carboni, G Laviola, A G Sadile, W Adriani, R Canese
Due to a hyperfunctioning mesocorticolimbic system, Naples-High-Excitability (NHE) rats have been proposed to model for the meso-cortical variant of attention deficit/hyperactivity disorder (ADHD). Compared to Naples Random-Bred (NRB) controls, NHE rats show hyperactivity, impaired non-selective attention (Aspide et al., 1998), and impaired selective spatial attention (Ruocco et al., 2009a, 2014). Alteration in limbic functions has been proposed; however, resulting unbalance among forebrain areas has not been assessed yet...
June 26, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28640211/a-novel-active-imaging-model-to-design-visual-systems-a-case-of-inspection-system-for-specular-surfaces
#14
Jorge Azorin-Lopez, Andres Fuster-Guillo, Marcelo Saval-Calvo, Higinio Mora-Mora, Juan Manuel Garcia-Chamizo
The use of visual information is a very well known input from different kinds of sensors. However, most of the perception problems are individually modeled and tackled. It is necessary to provide a general imaging model that allows us to parametrize different input systems as well as their problems and possible solutions. In this paper, we present an active vision model considering the imaging system as a whole (including camera, lighting system, object to be perceived) in order to propose solutions to automated visual systems that present problems that we perceive...
June 22, 2017: Sensors
https://www.readbyqxmd.com/read/28614153/further-analysis-of-the-predictability-of-corneal-endothelial-cell-density-estimates-when-polymegethism-is-present
#15
Michael J Doughty
PURPOSE: To assess variability in endothelial cell density (ECD) estimates when polymegethism (variance in cell areas) is present. METHODS: Using noncontact specular microscope images of the corneal endothelium, 4 sets of 20 cases were selected, which included 200 cells and had coefficient of variation values of less than 30% (group 1), 31%-40% (group 2), 41%-50% (group 3), and over 50% (group 4). A stepwise analysis was undertaken, 20 cells at a time, of the ECD estimates when using different numbers of cells for the calculations...
June 13, 2017: Cornea
https://www.readbyqxmd.com/read/28612330/endothelial-cell-changes-after-photorefractive-keratectomy-with-graded-usage-of-mitomycin-c
#16
Hamid Gharaee, Siamak Zarei-Ghanavati, Reza Alizadeh, Mojtaba Abrishami
PURPOSE: To compare differences in the endothelial cells before and after photorefractive keratectomy (PRK) for myopia with refractive error graded mitomycin C (MMC) application. METHODS: In a prospective randomized clinical trial, forty-eight myopic patients referred to Khatam-al-Anbia Eye Hospital, Mashhad, Iran, for PRK. Patients were treated with PRK by a Bausch and Lomb Technolas 217z excimer laser (Bausch and Lomb, Rochester, NY). MMC was applied after PRK 5 s for each diopter of spherical equivalent myopic refractive error corrected...
June 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28604861/interfacial-and-volumetric-sensitivity-of-the-dry-sintering-process-of-polymer-colloidal-crystals-a-thermal-transport-and-photonic-bandgap-study
#17
Fabian A Nutz, Markus Retsch
We introduce the in situ characterization of the dry sintering process of face-centred cubic colloidal crystals by two complementary techniques: thermal transport and photonic stopband characterization. Therefore, we employed time-dependent, isothermal laser flash analysis and specular reflectivity experiments close to the glass transition temperature of the colloidal crystal. Both methods yield distinctly different time constants of the film formation process. This discrepancy can be attributed to a volume- (photonic stopband) and interface-driven (thermal transport) sensitivity of the respective characterization method...
June 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28601345/comparison-of-12-month-anatomic-and-functional-results-between-z6-femtosecond-laser-assisted-and-manual-trephination-in-deep-anterior-lamellar-keratoplasty-for-advanced-keratoconus
#18
A Blériot, E Martin, P Lebranchu, K Zimmerman, L Libeau, M Weber, B Vabres, I Orignac
The management of severe keratoconus requires corneal transplantation, for which the gold standard is deep anterior lamellar keratoplasty (DALK), preserving the healthy Descemet's membrane and endothelium. The safety and reproducibility of corneal cuts have been improved by the evolution of femtosecond lasers in refractive surgery, and femtosecond laser in DALK would seem to provide the same advantages over the manual method. In our retrospective study, we compare functional and anatomical results of femtosecond-assisted DALK versus manual trephination DALK in patients with keratoconus in stage 4 of the Krumeich classification...
June 7, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28600523/wide-incidence-angle-insensitive-metamaterial-absorber-for-both-te-and-tm-polarization-using-eight-circular-sector
#19
Toan Trung Nguyen, Sungjoon Lim
In this paper, a wide incidence angle-insensitive metamaterial absorber is proposed using eight-circular-sector (ECS). Under normal incidence, the proposed absorber shows high absorptivity at different polarizations due to its symmetric geometry. Under oblique incidence, zero-reflection conditions for transverse electric (TE) and transverse magnetic (TM) polarization are different. Nevertheless, the proposed absorber shows high absorptivity under oblique incidence of both TE and TM polarization due to ECS. The performance of the proposed absorber was demonstrated with full-wave simulation and measurements...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28597601/endothelial-alterations-in-712-keratoconus-patients
#20
Susanne Goebels, Timo Eppig, Berthold Seitz, Nòra Szentmàry, Alan Cayless, Achim Langenbucher
PURPOSE: To investigate the effect of the severity of keratoconus on the corneal endothelium using specular microscopy. METHODS: Seven hundred and twelve eyes from the Homburg Keratoconus Center (HKC) database were included in this retrospective study. Corneal endothelium was evaluated using the Tomey EM-3000 specular microscope. Keratoconus-related topographic and tomographic data were obtained from Scheimpflug-based tomography (Oculus Pentacam(®) HR). Eyes were classified into stages 0 (healthy) to 4 (severe keratoconus) according to the Topographic Keratoconus Classification (TKC)...
June 9, 2017: Acta Ophthalmologica
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