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https://www.readbyqxmd.com/read/28542407/the-influence-of-persistent-organic-pollutants-in-the-traditional-inuit-diet-on-markers-of-inflammation
#1
L K Schæbel, E C Bonefeld-Jørgensen, H Vestergaard, S Andersen
Concentrations of persistent organic pollutants (POPs) are high in Inuit living predominately on the traditional marine diet. Adverse effects of POPs include disruption of the immune system and cardiovascular diseases that are frequent in Greenland Inuit. We aimed to assess the association between exposure to POPs from the marine diet and inflammation, taking into account other factors such as vitamin D. We invited Inuit and non-Inuit living in settlements or the town in rural East Greenland or in the capital city Nuuk...
2017: PloS One
https://www.readbyqxmd.com/read/28542115/exposure-to-oral-contraceptives-increases-the-risk-for-development-of-inflammatory-bowel-disease-a-meta-analysis-of-case-controlled-and-cohort-studies
#2
Ronald Ortizo, Stephanie Y Lee, Emily T Nguyen, Mohammad Mazen Jamal, Matthew M Bechtold, Douglas L Nguyen
BACKGROUND: The oral contraceptive pill (OCP) is a widely used method of contraception. There have been conflicting studies linking the use of OCPs to the development of inflammatory bowel disease (IBD). The intent of this meta-analysis is to better define the association between OCP exposure and the risk for development of IBD. METHODS: A thorough search of multiple databases, including Scopus, Cochrane, MEDLINE/PubMed, and CINAHL, and abstracts from major gastroenterology meetings was performed (October, 2016)...
May 24, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28537030/chemical-contamination-assessment-in-mangrove-lined-caribbean-coastal-systems-using-the-oyster-crassostrea-rhizophorae-as-biomonitor-species
#3
Javier R Aguirre-Rubí, Andrea Luna-Acosta, Nestor Etxebarría, Manu Soto, Félix Espinoza, Michael J Ahrens, Ionan Marigómez
This paper aims to contribute to the use of mangrove cupped oyster, Crassostrea rhizophorae, as a biomonitor species for chemical contamination assessment in mangrove-lined Caribbean coastal systems. Sampling was carried out in eight localities (three in Nicaragua and five in Colombia) with different types and levels of contamination. Oysters were collected during the rainy and dry seasons of 2012-2013 and the tissue concentrations of metals, polycyclic aromatic hydrocarbons (PAHs), and persistent organic pollutants (POPs) were determined...
May 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28528412/bioindicators-of-organochlorine-pesticides-in-the-sea-of-okhotsk-and-the-western-bering-sea
#4
Vasiliy Yu Tsygankov, Margarita D Boyarova, Olga N Lukyanova, Nadezhda K Khristoforova
Organochlorine pesticides (OCPs), such as HCHs and DDTs, are still used as pesticides in the Southern Hemisphere and can reach the North Pacific due to long range atmospheric transfer. Marine mammals (Pacific walrus Odobenus rosmarus divergens, gray whale Eschrichtius robustus), the seabirds (Pacific gull Larus schistisagus, crested auklet Aethia cristatella, auklet crumb Aethia pusilla, northern fulmar Fulmarus glacialis, and grey petrel Oceanodroma furcata) and Pacific salmon (pink Oncorhynchus gorbuscha, chum O...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28513152/a-molecular-mechanism-for-nonphotochemical-quenching-in-cyanobacteria
#5
Yue Lu, Haijun Liu, Rafael Saer, Veronica L Li, Hao Zhang, Liuqing Shi, Carrie Goodson, Michael L Gross, Robert E Blankenship
The cyanobacterial orange carotenoid protein (OCP) protects photosynthetic cyanobacteria from photodamage by dissipating excess excitation energy collected by phycobilisomes (PBS) as heat. Dissociation of the PBS-OCP complex in vivo is facilitated by another protein known as the fluorescence recovery protein (FRP), which primarily exists as a dimeric complex. We used various mass spectrometry (MS)-based techniques to investigate the molecular mechanism of this FRP-mediated process. FRP in the dimeric state (dFRP) retains its high affinity for the C-terminal domain (CTD) of OCP in the red state (OCP(r))...
May 25, 2017: Biochemistry
https://www.readbyqxmd.com/read/28511371/study-of-serum-total-psa-and-free-psa-as-an-oncological-marker-in-breast-tumour
#6
Elteza Tahjiba Jahir, Runi Devi, Bibhuti Bhushan Borthakur
INTRODUCTION: Breast Cancer (BC) cases are rising alarmingly all over the world and India is not an exception. This rising trend is due to an increased age at first child birth, decreased breast feeding, and the changing lifestyle mostly in urban India. With the advent of more sensitive methodologies and research works in this field, it has been suggested that Prostate Specific Antigen (PSA) plays an important role in the pathogenesis of breast cancer besides other established tumour markers...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28509683/conjunctival-squamous-cell-neoplasia-associated-with-ocular-cicatricial-pemphigoid
#7
Catherine J Choi, Frederick A Jakobiec, Fouad R Zakka, C Stephen Foster, James Chodosh, Suzanne K Freitag
The purpose of this study was to describe a possible causal relationship between ocular cicatricial pemphigoid (OCP) and ocular surface squamous neoplasia. Two middle-aged female patients with already diagnosed OCP were studied in regard to the subsequent onset of conjunctival squamous neoplasia. Their clinical histories, ocular examinations, clinical photographs, and results of biopsies and any ancillary immunofluorescent laboratory evaluation studies were carefully reviewed. One patient had a preinvasive squamous dysplasia and the other an invasive squamous cell carcinoma, both in the unequivocal setting of OCP with bilateral conjunctivitis, symblephara, and forniceal foreshortening...
May 15, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28503830/synthetic-ocp-heterodimers-are-photoactive-and-recapitulate-the-fusion-of-two-primitive-carotenoproteins-in-the-evolution-of-cyanobacterial-photoprotection
#8
Sigal Lechno-Yossef, Matthew R Melnicki, Han Bao, Beronda L Montgomery, Cheryl A Kerfeld
The Orange Carotenoid Protein (OCP) governs photoprotection in the majority of cyanobacteria. It is structurally and functionally modular, comprised of a C-terminal regulatory domain (CTD), an N-terminal effector domain (NTD) and a ketocarotenoid; the chromophore spans the two domains in the ground state and translocates fully into the NTD upon illumination. Using both the canonical OCP1 from Fremyella diplosiphon and the presumably more primitive OCP2 paralog from the same organism, we show that an NTD-CTD heterodimer forms when the domains are expressed as separate polypeptides...
May 15, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28503285/oral-contraceptive-related-transverse-sinus-thrombosis-as-an-initial-manifestation-of-antiphospholipid-syndrome-in-the-absence-of-systemic-lupus-erythematosus
#9
Payam Saadat, Reza Mohseni-Ahangar
BACKGROUND: Cerebral venous sinus thrombosis is a rare and potentially life-threatening neurologic manifestation of antiphospholipid syndrome. Oral contraceptive pills (OCP) may increase the risk of vascular events, even in people without family history of venous thrombosis. CASE PRESENTATION: A 31-year-old woman with four weeks of constant headache and history of taking OCP for one year has been selected for this study. The results of magnetic resonance imaging (MRI) of brain and venography confirmed a diagnosis of cerebral venous sinus thrombosis...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28497386/oral-contraceptive-pill-use-and-the-susceptibility-to-markers-of-exercise-induced-muscle-damage
#10
K M Hicks, G Onambélé-Pearson, K Winwood, C I Morse
PURPOSE: Firstly, to establish whether oral contraceptive pill (OCP) users are more susceptible to muscle damage compared to non-users, and secondly, to establish whether differences can be attributed to differences in patella tendon properties. METHODS: Nine female OCP users and 9 female non-users participated in the investigation. Combining dynamometry, electromyography and ultrasonography, patella tendon properties and vastus lateralis architectural properties were measured pre and during the first of 6 sets of 12 maximal voluntary eccentric knee extensions...
May 11, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28493680/legacy-and-current-use-insecticides-in-agricultural-sediments-from-south-china-the-impact-of-application-pattern-on-the-occurrence-and-risk
#11
Yanli Wei, Huizhen Li, Junjie Zhang, Jingjing Xiong, Xiaoyi Yi, Jing You
Legacy and current-use insecticides were analyzed in sediments collected from a typical rice planting region in South China. Total concentrations of insecticides varied from 1.63 to 775 ng g-1 with mean and median values of 67.0 and 11.5 ng g-1, respectively. Pyrethroids predominated pesticide composition (31.7%), followed by organophosphates (23.0%) and fiproles (20.8%). Sediment risk analysis showed that pyrethroids, fiproles and abamectin posed significant risk to benthic invertebrates in one-third of sediments...
May 11, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28492335/energy-storage-applications-for-a-ph-gradient-between-two-benzimidazole-ligated-ruthenium-complexes-that-engage-in-proton-coupled-electron-transfer-reactions-in-solution
#12
Daisuke Motoyama, Kai Yoshikawa, Hiroaki Ozawa, Makoto Tadokoro, Masa-Aki Haga
The judicious selection of pairs of benzimidazole-ligated ruthenium complexes allowed the construction of a rechargeable proton-coupled electron-transfer (PCET)-type redox battery. A series of ruthenium(II) and -(III) complexes were synthesized that contain substituted benzimidazoles that engage in PCET reactions. The formation of intramolecular Ru-C cyclometalation bonds stabilized the resulting ruthenium(III) complexes, in which pKa values of the imino N-H protons on the benzimidazoles are usually lower than those for the corresponding ruthenium(II) complexes...
May 11, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28477298/telomere-length-is-short-in-pcos-and-oral-contraceptive-does-not-affect-the-telomerase-activity-in-granulosa-cells-of-patients-with-pcos
#13
Ying Li, Bingbing Deng, Nengyong Ouyang, Ping Yuan, Lingyan Zheng, Wenjun Wang
PURPOSE: Our study aimed to investigate the association of telomerase activity (TA) and telomere length (TL) in granulosa cells (GCs) with IVF outcomes of polycystic ovary syndrome (PCOS) patients, and the effects of oral contraceptive pill (OCP) pretreatment on these two parameters. METHODS: One hundred sixty-three infertile women were enrolled and divided into a PCOS group (n = 65) and a non-PCOS group (n = 98). The PCOS group was further divided into an OCP pretreatment group (n = 35) and a non-OCP pretreatment group (n = 30), a TA <0...
May 6, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28477163/spatial-distribution-of-organochlorine-and-organophosphorus-pesticides-in-soil-groundwater-systems-and-their-associated-risks-in-the-middle-reaches-of-the-yangtze-river-basin
#14
Hongwei Pan, Hongjun Lei, Xiaosong He, Beidou Xi, Qigong Xu
Soil and groundwater samples were collected from paddy fields in the middle reaches of the Yangtze River Basin to study the occurrence and the risks associated with organochlorine pesticides (OCPs) and organophosphorus pesticides (OPPs) in soil and groundwater. Results showed that OCPs and OPPs were widely distributed throughout the study area. The levels of OCPs and OPPs in the soil were much lower than those specified by soil quality standards. However, the levels of four OCPs (heptachlors, aldrin, dieldrin, and γ-hexachlorocyclohexane) in groundwater were higher than those permitted by drinking water standards...
May 5, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28463822/organochlorine-pesticides-and-polychlorinated-biphenyls-in-human-adipose-tissue-from-northern-tunisia-current-extent-of-contamination-and-contributions-of-socio-demographic-characteristics-and-dietary-habits
#15
Amani Achour, Abdelkader Derouiche, Badreddine Barhoumi, Badreddine Kort, Driss Cherif, Sondes Bouabdallah, Mohsen Sakly, Khémais Ben Rhouma, Soufiane Touil, Mohamed Ridha Driss, Olfa Tebourbi
The aims of the present study were to investigate the current exposure levels of persistent organochlorine compounds (OCs) in adipose tissues intraoperatively collected from 40 patients over 20 years undergoing non-cancer-related surgery residing in Northern region of Tunisia (Bizerte), which constitutes an exemplary case, and examined association between levels of contamination and both socio-demographic characteristics and dietary habits. Concentration of hexachlorobenzene (HCB), hexachlorocyclohexane isomers (α-HCH, β-HCH, γ-HCH and δ-HCH), dichlorodiphenyltrichloroethane isomers (p,p'-DDT and o,p'-DDT) and metabolites (p,p'-DDE, o,p'-DDE, p,p'-DDD and o,p'-DDD) and 12 polychlorinated biphenyls (PCBs) congeners were measured using capillary gas chromatography with electron capture detector...
April 27, 2017: Environmental Research
https://www.readbyqxmd.com/read/28460875/persistent-organochlorine-residues-in-fish-and-sediments-collected-from-eastern-aegean-coast-levels-occurrence-and-ecological-risk
#16
Shareef K I Muzyed, Filiz Kucuksezgin, Nalan Tuzmen
Organochlorines were determined in fish and sediment collected from Izmir and Çandarlı Bays. The results indicated that ΣCyclodiens were generally predominant contaminants. In all samples, p,p'-DDE was the predominant DDT congener. Aroclors were found in noticeably higher levels than OCPs in sediment and the highest levels of Aroclors, OCPs were found in Nemrut which can be attributed to industrial activities. According to Sediment Quality Guidelines, DDTs were lower than the values that may cause adverse biological risk in sediment samples...
April 28, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28455811/historical-trends-of-polycyclic-aromatic-hydrocarbons-in-the-reservoir-sediment-of-the-dianchi-watershed-southwest-china
#17
Panpan Sun, Biao Xie, Yimin Song, Hao Yang, Yanhua Wang
Using gas-chromatography/mass spectrometry (GC-MS) method dating data ((210)Pb and (137)Cs) and OCPs signatures, the temporal distribution of polycyclic aromatic hydrocarbons (PAHs) was investigated in dated sediment core from Baoxianghe reservoir in Dianchi watershed, Southwest China. The concentrations of total PAHs were in the range of 162.3-762.2 ng g(-1) from 1945 to 2013. There showed an obvious increase from 1960s to 2000s. The distributions of PAHs were influenced by local population and Gross Domestic Product (GDP) during the period between1962 and 2004...
April 28, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28450833/optimal-control-based-stiffness-identification-of-an-ankle-foot-orthosis-using-a-predictive-walking-model
#18
Manish Sreenivasa, Matthew Millard, Martin Felis, Katja Mombaur, Sebastian I Wolf
Predicting the movements, ground reaction forces and neuromuscular activity during gait can be a valuable asset to the clinical rehabilitation community, both to understand pathology, as well as to plan effective intervention. In this work we use an optimal control method to generate predictive simulations of pathological gait in the sagittal plane. We construct a patient-specific model corresponding to a 7-year old child with gait abnormalities and identify the optimal spring characteristics of an ankle-foot orthosis that minimizes muscle effort...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28432879/seasonal-variation-and-health-risk-assessment-of-organochlorine-compounds-in-urban-soils-of-novi-sad-serbia
#19
Biljana D Škrbić, Vesna Marinković, Igor Antić, Anita Petrović Gegić
The aim of this paper was to determine spatial and seasonal variation of 6 indicator polychlorinated biphenyls (PCBs) and 18 organochlorine pesticides (OCPs) in urban soils of Novi Sad, Serbia. Sixty surface soil samples were collected during both winter and summer season, from different types of locations: schools, recreational areas, residential and industrial zones. Samples were treated using the method of accelerated solvent extraction, which allows simultaneous extraction and clean up of PCBs and OCPs...
April 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28432626/temporal-trends-of-lipophilic-persistent-organic-pollutants-in-serum-from-danish-nulliparous-pregnant-women-2011-2013
#20
Christian Bjerregaard-Olesen, Manhai Long, Mandana Ghisari, Bodil H Bech, Ellen A Nohr, Niels Uldbjerg, Tine B Henriksen, Jørn Olsen, Eva C Bonefeld-Jørgensen
The use of the lipophilic persistent organic pollutants (POPs) including polychlorinated biphenyls (PCBs) and several organochlorine pesticides (OCPs) has been prohibited for more than 30 years. In this study, we present the temporal trends of the lipophilic POP serum concentrations in Danish nulliparous pregnant women between 2011 and 2013. We randomly selected 197 pregnant women (gestational age 11-13) from the Aarhus Birth Cohort. The concentrations of the lipophilic POPs in the serum samples were analyzed using gas chromatography...
April 21, 2017: Environmental Science and Pollution Research International
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