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https://www.readbyqxmd.com/read/29786957/statistical-approaches-to-adjusting-weights-for-dependent-arms-in-network-meta-analysis
#1
Yu-Xuan Su, Yu-Kang Tu
Network meta-analysis compares multiple treatments in terms of their efficacy and harm by including evidence from randomized controlled trials. Most clinical trials use parallel design, where patients are randomly allocated to different treatments and receive only one treatment. However, some trials use within person designs such as split-body, split-mouth and cross-over designs, where each patient may receive more than one treatment. Data from treatment arms within these trials are no longer independent, so the correlations between dependent arms need to be accounted for within the statistical analyses...
May 22, 2018: Research Synthesis Methods
https://www.readbyqxmd.com/read/29786935/evaluation-of-pcr-primers-targeting-the-groel-gene-for-the-specific-detection-of-streptococcus-agalactiae-in-the-context-of-aquaculture
#2
W J Leigh, R N Zadoks, A Jaglarz, J Z Costa, G Foster, K D Thompson
AIMS: The aim of this study was to design a set of primers for specific detection and identification of Streptococcus agalactiae in polymerase chain reaction (PCR) that can detect a diverse range of S. agalactiae isolates from different hosts and that it is capable of discriminating between S. agalactiae and other species that are closely related or potentially present in aquaculture environments, notably Streptococcus iniae. METHODS AND RESULTS: Primers, based on the groEL2 gene of S...
May 22, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29786928/evaluation-of-medication-dose-omissions-amongst-inpatients-in-a-hospital-using-an-electronic-medication-management-system
#3
Katherine V Hunt, Andrew M Harding, Simone E Taylor, Colin Curtain
RATIONALE, AIMS, AND OBJECTIVES: Whilst many dose omissions cause no patient harm, inappropriate dose omissions have been associated with increased length of hospital stay, risk of sepsis, and mortality. This study aimed to comprehensively describe the prevalence and nature of omitted doses overall and of high risk medication dose omissions in an organization using an electronic Medication Management System. METHODS: A retrospective cross-sectional study was undertaken in an Australian tertiary referral health service...
May 22, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29786925/computed-tomographic-and-radiographic-bronchial-collapse-may-be-a-normal-characteristic-of-forced-expiration-in-dogs
#4
Hyunryung Kim, Young Joo Kim, Hanbin Lee, Taegeon An, Jin Yu, Hyounglok Yoon, Gayeon An, Jaihyun Jung, Jinhwa Chang, Dongwoo Chang
Tracheobronchomalacia has been diagnosed using radiography or bronchoscopy to confirm bronchial changes in luminal diameter during the respiratory cycle. However, studies in healthy humans suggest that some degree of bronchial collapse may be observed during the normal respiratory cycle. In this analytical study, the luminal diameter of the bronchus to each of the six pulmonary lobes and the mean percentage of expiratory collapse from end inspiratory, end expiratory, and two forced expiratory phases (10 and 15 ml/kg) were determined via computed tomography (CT) and radiography in 22 healthy Beagle dogs...
May 22, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29786924/reproductive-ecology-of-ocotea-catharinensis-an-endangered-tree-species
#5
Tiago Montagna, Juliano Zago da Silva, Tiago Georg Pickart, Maurício Sedrez Dos Reis
Ocotea catharinensis (Lauraceae) is an endangered tree species from the Brazilian Atlantic Rainforest. Currently, little is known about the reproductive ecology of this species. Aiming to propose conservation measures, we described aspects related to phenology, floral biology, pollination, seed dispersal, and mating system of O. catharinensis. We conducted phenological observations in 62 individuals for two years. In one reproductive event, we evaluated nectar production, stigmatic receptivity, and pollen viability...
May 22, 2018: Plant Biology
https://www.readbyqxmd.com/read/29786903/copper-catalyzed-allylic-c-h-alkynylation-via-cross-dehydrogenative-coupling
#6
Ahmad A Almasalma, Esteban Mejía
C-H bond functionalization is a well-developed concept that has been thoroughly studied and gives entry to rather complex molecules without the need of previous derivatization of the substrates, although the use of copper complexes for allylic C-H bond functionalization under oxidative conditions as an alternative to the well-established palladium-based methodologies remains largely underdeveloped. Here we show for the first time a selective cross-dehydrogenative coupling reaction between underivatized allylic substrates and terminal alkynes to produce 1,4-enynes in high yields in a single step, using an in situ synthesized copper catalyst and an oxidant...
May 22, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29786868/cis-acting-allele-specific-expression-ase-differences-induced-by-alcohol-and-impacted-by-sex-as-well-as-parental-genotype-of-origin
#7
Chiao-Ling Lo, Lawrence Lumeng, Richard L Bell, Tiebing Liang, Amy C Lossie, Williams M Muir, Feng C Zhou
BACKGROUND: Alcohol use disorders (AUDs) are influenced by complex interactions between the genetics of the individual and their environment. We have previously identified hundreds of polygenic genetic variants between the selectively bred high and low alcohol drinking (HAD and LAD) rat lines. Here we report allele specific expression (ASE) differences, between the HAD2 and LAD2 rat lines. METHODS: The HAD2 and LAD2 rats which have been sequenced were reciprocally crossed to generate 10 litters of F1 progeny...
May 22, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29786835/bilateral-asymmetry-of-the-humerus-in-neandertals-australian-aborigines-and-medieval-humans
#8
Anna Maria Kubicka, Wioletta Nowaczewska, Antoine Balzeau, Janusz Piontek
OBJECTIVES: Bilateral asymmetry of diaphyseal shape and size may be a reflection of relative activity levels and patterns of habitual biomechanical stress in the upper arms of Neandertals and Homo sapiens. The main purpose of our study was to assess the level of directional asymmetry of humeral cross sections in Neandertals, recent Australian aborigines, and medieval farmers. MATERIALS AND METHODS: Indices of directional and absolute asymmetry (%DA and %AA) of humeral cross-sectional properties in Neandertals and recent Homo sapiens were calculated...
May 22, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29786825/the-comparison-of-arthroscopic-acromioplasty-with-and-without-acromioclavicular-coplaning
#9
Nuri Aydın, Barış Kocaoğlu, Ender Sarıoğlu, Okan Tok, Osman Güven
BACKGROUND: Coplaning means the removal of medial acromial spurs and inferior aspect of the distal clavicle. The aim of the study was to evaluate the outcomes of arthroscopic acromioplasty with and without coplaning in patients without acromioclavicular (AC) joint arthritis. METHODS: Because of impingement syndrome, arthroscopic subacromial decompression and acromioplasty was performed in Group 1 (9 males/31 female). In addition, coplaning was performed in Group 2 (8 males/21 females) by two different surgeons...
May 2018: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29786768/risk-prediction-score-for-hiv-infection-development-and-internal-validation-with-cross-sectional-data-from-men-who-have-sex-with-men-in-china
#10
Lu Yin, Yuejuan Zhao, Meridith Blevins Peratikos, Liang Song, Xiangjun Zhang, Ruolei Xin, Zheya Sun, Yunan Xu, Li Zhang, Yifei Hu, Chun Hao, Yuhua Ruan, Yiming Shao, Sten H Vermund, Han-Zhu Qian
Receptive anal intercourse, multiple partners, condomless sex, sexually transmitted infections (STIs), and drug/alcohol addiction are familiar factors that correlate with increased human immunodeficiency virus (HIV) risk among men who have sex with men (MSM). To improve estimation to HIV acquisition, we created a composite score using questions from routine survey of 3588 MSM in Beijing, China. The HIV prevalence was 13.4%. A risk scoring tool using penalized maximum likelihood multivariable logistic regression modeling was developed, deploying backward step-down variable selection to obtain a reduced-form model...
May 21, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29786704/peri-implant-tissue-score-pits-as-a-measure-of-success-applied-to-869-dental-implants-from-a-retrospective-clinical-study
#11
Zbyněk Mazur, Ladislav Korábek, Daniel Mazur
OBJECTIVE: This article presents a methodology of a comprehensive score for assessment and monitoring of dental implant success from the peri-implant tissue perspective. It involves only standard and minimally invasive techniques accessible to general dental practices, without the need for special equipment. METHODS AND MATERIALS: The proposed score methodology combines existing consensual global knowledge regarding aspects of dental implant success with the standard examination tools accepted for regular recall assessment...
May 17, 2018: Quintessence International
https://www.readbyqxmd.com/read/29786658/melatonin-as-a-therapy-for-traumatic-brain-injury-a-review-of-published-evidence
#12
REVIEW
Nicole Osier, Emily McGreevy, Lan Pham, Ava Puccio, Dianxu Ren, Yvette P Conley, Sheila Alexander, C Edward Dixon
Melatonin (MEL) is a hormone that is produced in the brain and is known to bind to MEL-specific receptors on neuronal membranes in several brain regions. MEL's documented neuroprotective properties, low toxicity, and ability to cross the blood-brain-barrier have led to its evaluation for patients with traumatic brain injury (TBI), a condition for which there are currently no Food and Drug Administration (FDA)-approved therapies. The purpose of this manuscript is to summarize the evidence surrounding the use of melatonin after TBI, as well as identify existing gaps and future directions...
May 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29786631/comparison-between-elite-and-subelite-swimmers-on-dry-land-and-tumble-turn-leg-extensor-force-time-characteristics
#13
Julian V Jones, David B Pyne, G Greg Haff, Robert U Newton
Jones, JV, Pyne, DB, Haff, GG, and Newton, RU. Comparison between elite and subelite swimmers on dry land and tumble turn leg extensor force-time characteristics. J Strength Cond Res 32(6): 1762-1769, 2018-Elite swimmers demonstrate faster swimming turn times that are potentially a result of having better strength-power characteristics than subelite swimmers. We quantified differences between dry-land and swimming turn force-time characteristics in elite swimmers and subelite swimmers. Subelite (11 males: 17...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29786625/differences-in-glenohumeral-joint-rotation-and-peak-power-output-between-super-league-and-championship-rugby-league-players
#14
Matthew R Haines
Haines, MR. Differences in glenohumeral joint rotation and peak power output between Super League and Championship Rugby League players. J Strength Cond Res 32(6): 1685-1691, 2018-Rugby league is a high-intensity sport with large impact forces sustained during play, resulting in high prevalence of shoulder injury. Consequently, shoulder strength and player power are important considerations for injury prevention and performance. Additionally, professional teams regularly compete against semiprofessional teams, where differences in physical conditioning could be marked...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29786623/rating-of-perceived-exertion-as-a-method-of-volume-autoregulation-within-a-periodized-program
#15
Eric R Helms, Matt R Cross, Scott R Brown, Adam Storey, John Cronin, Michael C Zourdos
Helms, ER, Cross, MR, Brown, SR, Storey, A, Cronin, J, and Zourdos, MC. Rating of perceived exertion as a method of volume autoregulation within a periodized program. J Strength Cond Res 32(6): 1627-1636, 2018-The purpose of this investigation was to observe how a rating of perceived exertion (RPE)-based autoregulation strategy impacted volume performed by powerlifters. Twelve (26 ± 7 years, n = 9 men, n = 3 women) nationally qualified powerlifters performed the back squat, bench press, and deadlift 3x per week on nonconsecutive days in a session order of hypertrophy, power, and then strength; for 3 weeks...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29786545/eapci-presidential-criss-cross
#16
Andreas Baumbach, Michael Haude
No abstract text is available yet for this article.
May 20, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29786526/application-of-multiple-behaviour-change-models-to-identify-determinants-of-farmers-biosecurity-attitudes-and-behaviours
#17
I F Richens, J Houdmont, W Wapenaar, O Shortall, J Kaler, H O'Connor, M L Brennan
It has been recognised that few cattle farmers undertake biosecurity practices on their farms. Approaches that take into consideration individuals' preparedness for change, alongside beliefs thought to motivate the enactment of certain behaviours, may provide a framework for actuating tangible change. The aim of this study was to use a combination of behaviour change models to link beliefs with behaviour and identify possible key interventions to improve the uptake of biosecurity measures by dairy cattle farmers in Great Britain (GB)...
July 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29786516/immediate-or-deferred-adjustment-of-drug-regimens-in-multidose-drug-dispensing-systems
#18
Bram J Mertens, Henk-Frans Kwint, Rob J van Marum, Marcel L Bouvy
BACKGROUND: Multidose drug dispensing (MDD) is used to help patients take their medicines appropriately. Little is known about drug regimen changes within these MDD systems and how they are effectuated by the community pharmacist. Manual immediate adjustments of the MDD system could introduce dispensing errors. MDD guidelines therefore recommend to effectuate drug regimen changes at the start of a new MDD system. OBJECTIVE: The aim of this study was to investigate the frequency, type, procedure followed, immediate necessity, and time taken to make MDD adjustments...
May 18, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29786510/biochemical-markers-of-hypertension-prehypertension
#19
L Turgunova, B Koichubekov, A Turmuhambetova, M Sorokinam, Y E Laryushina, I Korshukov, A Shalygina, B Baidildina
OBJECTIVE: There are insufficient researches aimed at evaluating biochemical markers of mechanisms of formation of AH and lesion of target organs in hypertension and prehypertension. The aim of that research was to study the level of endothelial dysfunction markers and damage to the cardiovascular system in hypertension and prehypertension. PATIENTS AND METHODS: A cross-sectional study was performed among 938 people aged 18 to 65 years. All respondents were surveyed, blood pressure measured, for glucose, cholesterol, interleukin-6, sFAS, LIGHT, hFABP, NT-ProBNP and an Endocan concentrations were tested...
May 18, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29786475/connecting-structure-property-and-structure-function-relationships-across-the-disciplines-of-chemistry-and-biology-exploring-student-perceptions
#20
Kathryn P Kohn, Sonia M Underwood, Melanie M Cooper
While many university students take science courses in multiple disciplines, little is known about how they perceive common concepts from different disciplinary perspectives. Structure-property and structure-function relationships have long been considered important explanatory concepts in the disciplines of chemistry and biology, respectively. Fourteen university students concurrently enrolled in introductory chemistry and biology courses were interviewed to explore their perceptions regarding 1) the meaning of structure, properties, and function; 2) the presentation of these concepts in their courses; and 3) how these concepts might be related...
June 2018: CBE Life Sciences Education
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