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https://www.readbyqxmd.com/read/29235196/influence-of-particle-and-air-abrasion-moment-on-y-tzp-surface-characterization-and-bond-strength
#1
Samira Branco Martins, Filipe de Oliveira Abi-Rached, Gelson Luis Adabo, Paolo Baldissara, Renata Garcia Fonseca
PURPOSE: To evaluate the influence of particle and air-abrasion on the surface characterization and shear bond strength (SBS) of a Y-TZP ceramic with a resin cement. MATERIALS AND METHODS: Y-TZP specimens were air-abraded with 50 μm alumina particles; 120 μm alumina particles; 30 μm silica-coated alumina particles (Rocatec Soft); 110 μm silica-coated alumina particles (Rocatec Plus). Air-abrasion was performed before (BS); after (AS); before and after (BAS) zirconia sintering...
December 13, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29235046/efficiency-of-nitrogen-metabolism-in-beef-cattle-grazing-pasture-and-supplemented-with-different-protein-levels-in-the-rainy-season
#2
Renata Pereira da Silva-Marques, Joanis Tilemahos Zervoudakis, Luciana Keiko Hatamoto-Zervoudakis, Pedro Ivo José Lopes da Rosa E Silva, Núbia Bezerra do Nascimento Matos, Andresa Lazzarotto Feliciano, Rones Goulart de Paula Júnior, Luciano da Silva Cabral
Supplementation of animals in the rainy season is essential to maximise weight gain. Thus, the objective was to evaluate the effects of supplementation with low-, medium- and high-protein levels on nutritional parameters of grazing beef cattle in the rainy season. Eight rumen-cannulated Nellore bulls (437 kg body weight) were used in a 4 × 4 double Latin square design with four supplements and four experimental periods. The treatments were mineral supplement (ad libitum) and supplements with low-protein (LPSU), medium-protein (MPS) and high-protein (HPS) levels, providing 106, 408 and 601 g/day of crude protein (CP), respectively...
December 12, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29235021/occurrence-of-antimicrobial-agents-drug-resistant-bacteria-and-genes-in-the-sewage-impacted-vistula-river-poland
#3
Joanna Giebułtowicz, Stefan Tyski, Renata Wolinowska, Wanda Grzybowska, Tomasz Zaręba, Agata Drobniewska, Piotr Wroczyński, Grzegorz Nałęcz-Jawecki
Antimicrobial agents (antimicrobials) are a group of therapeutic and hygienic agents that either kill microorganisms or inhibit their growth. Their occurrence in surface water may reveal harmful effects on aquatic biota and challenge microbial populations. Recently, there is a growing concern over the contamination of surface water with both antimicrobial agents and multidrug-resistant bacteria. The aim of the study was the determination of the presence of selected antimicrobials at specific locations of the Vistula River (Poland), as well as in tap water samples originating from the Warsaw region...
December 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29234807/development-and-validation-of-a-deep-learning-system-for-diabetic-retinopathy-and-related-eye-diseases-using-retinal-images-from-multiethnic-populations-with-diabetes
#4
Daniel Shu Wei Ting, Carol Yim-Lui Cheung, Gilbert Lim, Gavin Siew Wei Tan, Nguyen D Quang, Alfred Gan, Haslina Hamzah, Renata Garcia-Franco, Ian Yew San Yeo, Shu Yen Lee, Edmund Yick Mun Wong, Charumathi Sabanayagam, Mani Baskaran, Farah Ibrahim, Ngiap Chuan Tan, Eric A Finkelstein, Ecosse L Lamoureux, Ian Y Wong, Neil M Bressler, Sobha Sivaprasad, Rohit Varma, Jost B Jonas, Ming Guang He, Ching-Yu Cheng, Gemmy Chui Ming Cheung, Tin Aung, Wynne Hsu, Mong Li Lee, Tien Yin Wong
Importance: A deep learning system (DLS) is a machine learning technology with potential for screening diabetic retinopathy and related eye diseases. Objective: To evaluate the performance of a DLS in detecting referable diabetic retinopathy, vision-threatening diabetic retinopathy, possible glaucoma, and age-related macular degeneration (AMD) in community and clinic-based multiethnic populations with diabetes. Design, Setting, and Participants: Diagnostic performance of a DLS for diabetic retinopathy and related eye diseases was evaluated using 494 661 retinal images...
December 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29234025/h3k14ac-is-linked-to-methylation-of-h3k9-by-the-triple-tudor-domain-of-setdb1
#5
Renata Z Jurkowska, Su Qin, Goran Kungulovski, Wolfram Tempel, Yanli Liu, Pavel Bashtrykov, Judith Stiefelmaier, Tomasz P Jurkowski, Srikanth Kudithipudi, Sara Weirich, Raluca Tamas, Hong Wu, Ludmila Dombrovski, Peter Loppnau, Richard Reinhardt, Jinrong Min, Albert Jeltsch
SETDB1 is an essential H3K9 methyltransferase involved in silencing of retroviruses and gene regulation. We show here that its triple Tudor domain (3TD) specifically binds to doubly modified histone H3 containing K14 acetylation and K9 methylation. Crystal structures of 3TD in complex with H3K14ac/K9me peptides reveal that peptide binding and K14ac recognition occurs at the interface between Tudor domains (TD) TD2 and TD3. Structural and biochemical data demonstrate a pocket switch mechanism in histone code reading, because K9me1 or K9me2 is preferentially recognized by the aromatic cage of TD3, while K9me3 selectively binds to TD2...
December 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/29232677/presence-of-initial-caries-lesions-as-a-risk-factor-for-caries-in-preschool-children-a-cohort-study
#6
Renata S Guedes, Chaiana Piovesan, Thiago M Ardenghi, Bruno Emmanuelli, Mariana M Braga, Fausto M Mendes
The aim of this study was to evaluate the influence of initial noncavitated caries lesions on cavitated caries increment in preschool children. A 2-year cohort study was designed to include the participants of a survey on dental caries performed in 2010. Preschool children (12-59 months old) were examined for dental caries and classified as children with no caries lesions, with only initial lesions, with at least 1 moderate caries lesion, and with extensive lesions. Socioeconomic data were also collected. After 2 years, 466 children were re-examined (follow-up rate of 72...
December 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29231974/direct-determination-of-amino-acids-in-brewery-worts-produced-by-different-processes-by-capillary-zone-electrophoresis
#7
Renata Corrêa de Carvalho, Thiago Rocha Dos Santos Mathias, Annibal Duarte Pereira Netto, Flávia Ferreira de Carvalho Marques
The direct and simultaneous determination of cysteine, histidine, phenylalanine, lysine, tryptophan and arginine in brewery worts by Capillary Zone Electrophoresis (CZE) was applied to evaluate the effects of temperature control and protease supplementation during mashing on the changes of these amino acids (AAs) wort composition. A cation exchange resin was used for AAs extraction from wort samples prior to CZE determination. The separation was achieved using a 50 mmol L-1 phosphate buffer at pH 12.5, containing 0...
December 12, 2017: Electrophoresis
https://www.readbyqxmd.com/read/29231904/protective-effects-of-%C3%AF-3-pufa-in-anthracycline-induced-cardiotoxicity-a-critical-review
#8
REVIEW
Simona Serini, Renata Ottes Vasconcelos, Renata Nascimento Gomes, Gabriella Calviello
It has been demonstrated that ω-3 polyunsaturated fatty acids (ω-3 PUFA) may exert a beneficial role as adjuvants in the prevention and treatment of many disorders, including cardiovascular diseases and cancer. Particularly, several in vitro and in vivo preclinical studies have shown the antitumor activity of ω-3 PUFA in different kinds of cancers, and several human studies have shown that ω-3 PUFA are able to decrease the risk of a series of cardiovascular diseases. Several mechanisms have been proposed to explain their pleiotropic beneficial effects...
December 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29229240/brain-functional-and-perfusional-alterations-in-schizophrenia-an-arterial-spin-labeling-study
#9
Ícaro A F Oliveira, Tiago M Guimarães, Roberto M Souza, Antônio C Dos Santos, João Paulo Machado-de-Sousa, Jaime E C Hallak, Renata F Leoni
Schizophrenia is a severe mental disorder that affects the anatomy and function of the brain, with an impact on one's thoughts, feelings, and behavior. The purpose of the study was to investigate cerebral blood flow (CBF) and brain connectivity in a group of patients with schizophrenia. Pseudo-continuous arterial spin labeling (pCASL) images were acquired from 28 patients in treatment and 28 age-matched healthy controls. Mean CBF and connectivity patterns were assessed. Schizophrenia patients had decreased CBF in the bilateral frontal pole and superior frontal gyrus, right medial frontal gyrus, triangular and opercular parts of the inferior frontal gyrus, posterior division of the left supramarginal gyrus, superior and inferior divisions of the left lateral occipital cortex, and bilateral occipital pole...
December 5, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29229139/comparison-of-the-lund-and-browder-table-to-computed-tomography-scan-three-dimensional-surface-area-measurement-for-a-pediatric-cohort
#10
R Wolfgang Rumpf, William C L Stewart, Stephen K Martinez, Chandra Y Gerrard, Natalie L Adolphi, Rajan Thakkar, Alan Coleman, Adrian Rajab, William C Ray, Renata Fabia
BACKGROUND: Treating burns effectively requires accurately assessing the percentage of the total body surface area (%TBSA) affected by burns. Current methods for estimating %TBSA, such as Lund and Browder (L&B) tables, rely on historic body statistics. An increasingly obese population has been blamed for increasing errors in %TBSA estimates. However, this assumption has not been experimentally validated. We hypothesized that errors in %TBSA estimates using L&B were due to differences in the physical proportions of today's children compared with children in the early 1940s when the chart was developed and that these differences would appear as body mass index (BMI)-associated systematic errors in the L&B values versus actual body surface areas...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29228887/can-whole-body-vibration-exercises-affect-growth-hormone-concentration-a-systematic-review
#11
Laisa Liane Paineiras-Domingos, Danúbia da Cunha de Sá-Caputo, Eloá Moreira-Marconi, Danielle Soares Morel, Carla da Fontoura Dionello, Cintia Renata Sousa-Gonçalves, Éric Heleno Freire Ferreira Frederico, Pedro Jesus Marín, Sofia Tamini, Alessandro Sartorio, Mario Bernardo-Filho
Whole body vibration (WBV) has been recognized as an effective alternative exercise modality to resistance exercise for its ability in enhancing force and power, generating capacity in skeletal muscle, increasing bone mass and improving cardiovascular function. Since the effect of WBV exercises on growth hormone (GH) levels has been never compared and discussed, the aim of this study was to review systematically the literature to verify the WBV effects on GH concentration. By using PubMed, Scopus and PEDRo databases with the keywords 'growth hormone' or GH and 'whole body vibration' or WBV, we found and analysed 12 papers (182 subjects recruited), verifying their level of evidence (National Health and Medical Research Council hierarchy of evidence) and the methodological quality (PEDRo scale)...
October 2017: Growth Factors
https://www.readbyqxmd.com/read/29226825/desacetyl-%C3%AE-melanocyte-stimulating-hormone-and-%C3%AE-melanocyte-stimulating-hormone-are-required-to-regulate-energy-balance
#12
Kathleen G Mountjoy, Alexandre Caron, Kristina Hubbard, Avik Shome, Angus C Grey, Bo Sun, Sarah Bould, Martin Middleditch, Beau Pontré, Ailsa McGregor, Paul W R Harris, Renata Kowalczyk, Margaret A Brimble, Rikus Botha, Karen M L Tan, Sarah J Piper, Christina Buchanan, Syann Lee, Anthony P Coll, Joel K Elmquist
OBJECTIVE: Regulation of energy balance depends on pro-opiomelanocortin (POMC)-derived peptides and melanocortin-4 receptor (MC4R). Alpha-melanocyte stimulating hormone (α-MSH) is the predicted natural POMC-derived peptide that regulates energy balance. Desacetyl-α-MSH, the precursor for α-MSH, is present in brain and blood. Desacetyl-α-MSH is considered to be unimportant for regulating energy balance despite being more potent (compared with α-MSH) at activating the appetite-regulating MC4R in vitro...
November 24, 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/29226780/individuals-perception-about-upper-limb-influence-on-participation-after-stroke-an-observational-study
#13
Renata Morales Banjai, Sandra Maria Sbeghen Ferreira de Freitas, Flavia Paiva da Silva, Sandra Regina Alouche
Background Stroke can compromise upper limb performance and influence the individual's participation in real life situations. Objective To investigate how components of body function and activity affect the individuals' self-perception of their participation after stroke. Methods In this observational study, the International Classification of Functioning, Disability and Health was used as model. Body function was assessed by palmar grip and pinch strength; Ashworth modified scale; Fugl-Meyer scale; and Motor-Free Visual Perception Test...
December 10, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29226334/early-stage-olfactory-neuroblastoma-and-the-impact-of-resecting-dura-and-olfactory-bulb
#14
Ashley C Mays, Diana Bell, Renata Ferrarotto, Jack Phan, Dianna Roberts, Clifton D Fuller, Steven J Frank, Shaan M Raza, Michael E Kupferman, Franco DeMonte, Ehab Y Hanna, Shirley Y Su
OBJECTIVE: Compare outcomes of patients with olfactory neuroblastoma (ONB) without skull base involvement treated with and without resection of the dura and olfactory bulb. METHODS: Retrospective review of ONB patients treated from 1992 to 2013 at the MD Anderson Cancer Center (The University of Texas, Houston, Texas, U.S.A.). Primary outcomes were overall and disease-free survival. RESULTS: Thirty-five patients were identified. Most patients had Kadish A/B...
December 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29225943/how-income-and-food-prices-influence-global-dietary-intakes-by-age-and-sex-evidence-from-164-countries
#15
Andrew Muhammad, Anna D'Souza, Birgit Meade, Renata Micha, Dariush Mozaffarian
Background: While income and prices are key drivers of dietary choices, how their influence varies by food category, nation, and demographics is not well established. Based on intake data for 164 countries and 11 food categories, we examined how income and food prices relate to food intake globally, including by world region, age, and sex. Methods: We used 2010 intake data from the Global Dietary Database, the first database of consumption estimates for major food categories by country, age, and sex...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29223962/evaluation-of-seven-rapid-tests-for-syphilis-available-in-brazil-using-defibrinated-plasma-panels
#16
Maria Luiza Bazzo, Leonardo Rapone da Motta, Renata Cristina Messores Rudolf-Oliveira, Alisson Bigolin, Lisléia Golfetto, Fábio Mesquita, Adele Schwartz Benzaken, Pamela Cristina Gaspar, Ana Flavia Nacif P Coelho Pires, Orlando da Costa Ferreira Júnior, Miriam Franchini
OBJECTIVES: In 2012, the WHO estimated that 6 million new cases of syphilis per year would occur worldwide, including 937 000 in Brazil. Early diagnosis and treatment of syphilis are essential to reduce morbidity and prevent transmission. The availability of rapid tests (RTs) for this diagnosis means that testing can be performed more quickly, as a point-of-care test, even in non-laboratory environments and requires only simple technical training to antibodies detection. The objective of this study was to evaluate the performance and operational aspects of seven commercially available RTs for syphilis in Brazil...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29223797/clinical-impact-of-adjuvant-radiation-therapy-delay-after-neoadjuvant-chemotherapy-in-locally-advanced-breast-cancer
#17
Saulo Brito Silva, Allan Andresson Lima Pereira, Gustavo Nader Marta, Kennya Medeiros Lopes de Barros Lima, Thiago Brasileiro de Freitas, Adriana Reis Brandão Matutino, Manoel Carlos Leonardi de Azevedo Souza, Renata Gondim Meira Velame de Azevedo, Pedro Antonio Hermida de Viveiros, Julianne Maria da Silva Lima, José Roberto Filassi, Heloísa de Andrade Carvalho, José Roberto Morales Piato, Max S Mano
BACKGROUND: and Purpose: Post-operative radiation therapy (PORT) is usually indicated for patients with breast cancer (BC) after neoadjuvant chemotherapy (NAC) and surgery. However, the optimal timing to initiation of PORT is currently unknown. MATERIAL AND METHODS: We retrospectively evaluated data from patients with BC who received PORT after NAC and surgery at our institution from 2008 to 2014. Patients were categorized into three groups according to the time between surgery and PORT: <8 weeks, 8-16 weeks and >16 weeks...
December 6, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29223587/molecular-characterization-of-theileria-equi-in-horses-from-the-state-of-rio-de-janeiro-brazil
#18
Maristela Peckle, Marcus Sandes Pires, Claudia Bezerra da Silva, Renata Lins da Costa, Gabriela Lopes Vivas Vitari, Marcus Vinicius Xavier Senra, Roberto Júnio Pedroso Dias, Huarrisson Azevedo Santos, Carlos Luiz Massard
Theileria equi is one of the etiologic agents of the equine piroplasmosis. This infectious disease is transmitted by ticks and is a worldwide problem in the international horse movement. The 18S rRNA gene of T. equi is often used for genotyping and phylogenetic purpose. This study aimed to analyze the degree of the heterogeneity of the 18S rRNA gene of T. equi in horses from the state of Rio de Janeiro, Brazil. The complete T. equi 18S rRNA sequences were obtained from twenty naturally infected horses. The PCR amplicons were cloned and sequenced...
November 28, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29223571/noval-nitroaromatic-compound-activates-autophagy-and-apoptosis-pathways-in-hl60%C3%A2-cells
#19
Gabriele Mendes M C Perdigão, Marcela Silva Lopes, Lucas Bonfim Marques, Pedro Henrique Dias Moura Prazeres, Kamila de Sousa Gomes, Renata Barbosa de Oliveira, Mauro Cunha Xavier Pinto, Elaine Maria de Souza-Fagundes
N-(2-butanoyloxyethyl)-4-(chloromethyl)-3-nitrobenzamide (NBCN) is a nitroaromatic bioreductible compound with cytotoxic effects in cancer cells lines. The aim of this work was investigated the molecular mechanisms involved in cell death promoted by NBCN on HL60 cells line. We observed that NBCN treatment increased intracellular ROS, reduced mitochondria membrane potential (ΔΨm). The treatment also induced morphological changes, phosphatidylserine exposure, cell cycle arrest in G2/M-phase, DNA condensation and fragmentation in HL60 cells, but did not showed cytotoxic effects on normal human peripheral blood mononuclear cells (PBMC)...
December 6, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29222670/venetoclax-for-treating-chronic-lymphocytic-leukaemia-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#20
REVIEW
Hema Mistry, Chidozie Nduka, Martin Connock, Jill Colquitt, Theodoros Mantopoulos, Emma Loveman, Renata Walewska, James Mason
Venetoclax is licensed to treat relapsed or refractory (R/R) chronic lymphocytic leukaemia (CLL). As part of the Single Technology Appraisal (STA) ID944, the National Institute for Health and Care Excellence (NICE) invited AbbVie, the manufacturer, to submit evidence on the use of venetoclax, within its licensed indication. The Evidence Review Group (ERG), Warwick Evidence, was asked to provide an independent and critical review of the submitted evidence. Evidence came from three single-arm trials in CLL patients with or without 17p deletion [del(17p])/TP53 chromosomal abnormalities...
December 8, 2017: PharmacoEconomics
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