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https://www.readbyqxmd.com/read/29924226/case-for-diagnosis-erythroderma-as-manifestation-of-hypereosinophilic-syndrome
#1
Maira Renata Merlotto, Lucas Oliveira Cantadori, Delmo Sakabe, Hélio Amante Miot
Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. A 36-year-old male with no comorbidities presented progressive erythroderma, pruritus, peripheral neuropathy, and eosinophilia in the previous seven months...
June 2018: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29924213/evaluation-of-polyamide-surgical-mesh-as-an-abdominal-ventral-implant-in-rabbits
#2
Renata Gebara Sampaio Dória, Silvio Henrique de Freitas, Yumi de Barcelos Hayasaka, Maria Cristina Ferrarini Nunes Soares Hage, Ricardo de Francisco Strefezzi, Adriano Bonfin Carregaro, Gustavo Morandini Reginato, Carlos Eduardo Ambrósio, Alois Foltran Müller
PURPOSE: To evaluate abdominal ventral wound healing by using a specific biomaterial, a handmade polyamide surgical mesh. METHODS: A surgical incisional defect was made in ten rabbits to simulate a hernia in the ventral abdominal musculature. A polyamide surgical mesh was used in hernioplasty. They were monitored for surgical wound healing, and macroscopically and histologically evaluated at the end of the experiment. The polyamide surgical mesh did not cause foreign body reaction, pain, edema, or infection in the surgical site...
May 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29923259/chronic-pain-in-narcolepsy-type-1-and-type-2-an-underestimated-reality
#3
Renata C Cremaschi, Camila Hirotsu, Sergio Tufik, Fernando M Coelho
Narcolepsy is a rare sleep disorder classified in types 1 and 2. The co-morbidities of narcolepsy type 1, with hypocretin-1 deficiency, are established. Hypocretin-1 in the central and peripheral nervous systems regulates nociception and pain. However, the patients with narcolepsy type 2 have similar excessive daytime sleepiness and co-morbidities without elucidation. The objective of the study was to determine the frequency and the characteristic of chronic pain according to the type of narcolepsy. We also investigated the effect of the interaction between the nutritional status and the type of narcolepsy...
June 19, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29923151/protein-profiles-of-bacteriophages-of-the-family-myoviridae-like-induced-on-m-haemolytica
#4
Renata Urban-Chmiel, Andrzej Wernicki, Jacek Wawrzykowski, Andrzej Puchalski, Anna Nowaczek, Marta Dec, Diana Stęgierska, Mohammed Mijbas Mohammed Alomari
The aim of study was to isolate, characterize and analyse the protein profiles of Myoviridae-like bacteriophages obtained from M. haemolytica using MALDI TOF mass spectrometry. The material consisted of the M. haemolytica reference strain ATCC® BAA410, reference serotypes A1, A2, A5, A6, A7, A9, and A11, and wild-type isolates of serotype A1. Bacteriophage morphology was examined with a transmission electron microscope. The proteins were separated in SDS-PAGE and two-dimensional electrophoresis and characterized by MALDI-TOF...
June 19, 2018: AMB Express
https://www.readbyqxmd.com/read/29922906/structure-function-relationships-of-the-mre11-protein-in-the-control-of-dna-end-bridging-and-processing
#5
REVIEW
Antonio Marsella, Corinne Cassani, Erika Casari, Renata Tisi, Maria Pia Longhese
The evolutionarily conserved Mre11-Rad50-Xrs2 (MRX) complex cooperates with the Sae2 protein in initiating resection of DNA double-strand breaks (DSBs) and in maintaining the DSB ends tethered to each other for their accurate repair. How these MRX-Sae2 functions contribute to DNA damage resistance is not understood. By taking advantage of mre11 alleles that suppress the hypersensitivity of sae2∆ cells to genotoxic agents, we have recently found that Mre11 can be divided in two structurally distinct domains that support resistance to genotoxic agents by mediating different processes...
June 19, 2018: Current Genetics
https://www.readbyqxmd.com/read/29922375/changes-in-injury-risk-mechanisms-after-soccer-specific-fatigue-in-male-youth-soccer-players
#6
Michal Lehnert, Mark De Ste Croix, Zuzana Xaverova, Michal Botek, Renata Varekova, Amr Zaatar, Ondrej Lastovicka, Petr Stastny
The aim of this study was to examine the acute effects of soccer specific fatigue on muscular and neuromuscular function in male youth soccer players. Elite soccer players (n = 20; age 15.7 ± 0.5 y; body height 177.75 ± 6.61 cm; body mass 67.28 ± 8.29 kg) were measured before and after soccer specific exercise (SAFT90 ). The reactive strength index (RSI) was determined by a drop jump test, leg stiffness (LS) by a 20 sub-maximal two-legged hopping test, and a functional hamstring to quadriceps strength ratio from isokinetic concentric and eccentric strength of the dominant and non-dominant leg (measured at angular velocities of 1...
June 2018: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29921501/tapentadol-a-representative-of-a-new-class-of-mor-nri-analgesics
#7
REVIEW
Renata Zajączkowska, Barbara Przewłocka, Magdalena Kocot-Kępska, Joanna Mika, Wojciech Leppert, Jerzy Wordliczek
Tapentadol is a centrally acting analgesic with a dual mode of action as a μ-opioid receptor (MOR) agonist and a noradrenaline reuptake inhibitor (NRI). It was initially approved by the US Food and Drug Administration in November 2008 for the treatment of moderate-to-severe acute pain in adult patients, and in August 2011, for chronic pain in an prolonged release form in the same population. Due to its limited protein binding capacity, the absence of active metabolites and significant microsomal enzyme induction or inhibition, tapentadol has a limited potential for drug-drug interactions...
January 31, 2018: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29921335/nasal-mites-mesostigmata-rhinonyssidae-in-african-penguins-spheniscus-demersus
#8
Ralph Eric Thijl Vanstreels, Heather Proctor, Albert Snyman, Renata Hurtado, Katrin Ludynia, Nola J Parsons, Pierre A Pistorius
Rhinonyssids are obligate haematophagous mites that parasitize the nasal cavity of vertebrates, and occur in a wide range of birds worldwide. Two species of nasal mites are known to occur in penguins: Rhinonyssus sphenisci, which has been recorded from Humboldt and Magellanic penguins (Spheniscus humboldti and S. magellanicus, respectively), and Rhinonyssus schelli, which has been recorded in Adélie and Gentoo penguins (Pygoscelis adeliae and P. papua, respectively). We examined the nasal cavity of African penguins (Spheniscus demersus) that died while under care at a rehabilitation centre (N = 40) or that were found dead at breeding colonies (N = 67)...
June 20, 2018: Parasitology
https://www.readbyqxmd.com/read/29920366/genotoxic-effects-of-bnsp-6-a-lys-49-phospholipase-a-2-pla-2-homologue-from-bothrops-pauloensis-snake-venom-on-mda-mb-231-breast-cancer-cells
#9
Makswell Almeida Silva, Daiana Silva Lopes, Samuel Cota Teixeira, Sarah Natalie Cirilo Gimenes, Fernanda Van Petten Vasconcelos Azevedo, Lorena Polloni, Bruna Cristina Borges, Marcelo Santos da Silva, Marcelo José Barbosa, Robson José de Oliveira Júnior, Maria Carolina Elias, Claudio Vieira da Silva, Kelly Aparecida Geraldo Yoneyama, Veridiana de Melo Rodrigues, Renata Santos Rodrigues
Herein we evaluated the genotoxic effects of BnSP-6, a Lys-49 phospholipase A2 (PLA2 ) from Bothrops pauloensis, on breast cancer cells. BnSP-6 was able to induce a higher cytotoxic and genotoxic activity in MDA-MB-231 cells, when compared to MCF10A (a non-tumorigenic breast cell line), suggesting that this protein presented a possible preference for cancer cells. BnSP-6 inhibited MDA-MB-231 proliferation at 24, 48 and 72 h. In addition, BnSP-6 induced significant increase in the percentage of TUNEL-positive cells, a marker of DNA damage...
June 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29917065/contribution-of-chronic-conditions-to-gender-disparities-in-health-expectancies-in-belgium-2001-2004-and-2008
#10
Renata T C Yokota, Willma J Nusselder, Jean-Marie Robine, Jean Tafforeau, Françoise Renard, Patrick Deboosere, Herman Van Oyen
Background: We aimed to investigate the contribution of chronic conditions to gender differences in disability-free life expectancy (DFLE) and life expectancy with disability (LED) in Belgium in 2001, 2004 and 2008. Methods: Data on disability and chronic conditions from participants of the 2001, 2004 and 2008 Health Interview Surveys in Belgium were used to estimate disability prevalence by cause using the attribution method. Disability prevalence was applied to life tables to estimate DFLE and LED using the Sullivan method...
June 15, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29916999/evaluation-of-ocular-surface-disease-in-patients-with-glaucoma-clinical-parameters-self-report-assessment-and-keratograph-analysis
#11
Renata C Portela, Nikoly T Fares, Lilian F Machado, Amanda F São Leão, Denise de Freitas, Augusto Paranhos, Tiago S Prata, Carolina P B Gracitelli
PURPOSE: To assess ocular surface disease (OSD) in glaucoma using clinical parameters, self-report assessment and keratograph analysis. METHODS: A total of 30 glaucoma patients and 27 subjects with cataracts (control group) were enrolled in the study. Only glaucoma patients who were using at least 1 topical intraocular pressure (IOP)-lowering medication were included. An ophthalmological examination was performed, including tear break-up time, assessment of conjunctival hyperemia and keratitis, and completion of the Ocular Surface Disease Index (OSDI) questionnaire...
June 18, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29915949/dietary-supplements-and-fatigue-in-patients-with-breast-cancer-a-systematic-review
#12
REVIEW
Paula Tâmara Vieira Teixeira Pereira, Andréa Dias Reis, Renata Rodrigues Diniz, Franciléia Andrade Lima, Richard Diego Leite, Mayara Cristina Pinto da Silva, Rosane Nassar Meireles Guerra, Érica Brandão de Moraes Vieira, João Batista Santos Garcia
PURPOSE: Cancer-related fatigue (CRF) is defined as a distressing, persistent, and subjective sense of physical or emotional and/or cognitive exhaustion. The treatment of CRF includes pharmacological and non-pharmacological therapies; dietary strategies with promising results have also been used. This study aimed to identify dietary supplements that improve fatigue in patients with breast cancer. METHODS: A systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...
June 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29915695/long-term-experimental-in-situ-farming-of-crambe-crambe-demospongiae-poecilosclerida
#13
Andrea Padiglia, Fabio D Ledda, Bachisio M Padedda, Roberto Pronzato, Renata Manconi
Background: The marine sponge Crambe crambe was chosen as an experimental model of sustainable shallow-water mariculture in the Sardinian Sea (Western Mediterranean) to provide biomass with high potential in applied research. Methods: Explants were cultured in four long-term experiments (19 and 31 months at ca. 2.5 m depth), to determine the suitability of new culture techniques by testing substrata and seeding time (season), and monitoring survival and growth. Explants were excised and grown in an experimental plant close to the wild donor sponge population...
2018: PeerJ
https://www.readbyqxmd.com/read/29915563/immunological-profile-and-predisposition-to-autoimmunity-in-girls-with-turner-syndrome
#14
Aneta Monika Gawlik, Elzbieta Berdej-Szczot, Dorota Blat, Renata Klekotka, Tomasz Gawlik, Ewa Blaszczyk, Magdalena Hankus, Ewa Malecka-Tendera
Objective: The risk of autoimmune diseases (AD) in patients with Turner Syndrome (TS) is twice higher than in the general female population and four times higher than in the male population. The causes of the increased incidence of AD in TS are still under discussion. We hypothesized the presence of a specific humoral, cellular, and regulatory T cell (Treg) immunity profile which predisposes to AD, disorders of immunity, and disorders of immune regulation. Methods: The study encompassed 37 girls with TS and with no signs of infection...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29915550/dealing-with-the-aftermath-of-mass-disasters-a-field-study-on-the-application-of-emdr-integrative-group-treatment-protocol-with-child-survivors-of-the-2016-italy-earthquakes
#15
Cristina Trentini, Marco Lauriola, Alessandro Giuliani, Giada Maslovaric, Renata Tambelli, Isabel Fernandez, Marco Pagani
This study explored the effects of the EMDR Integrative Group Treatment Protocol (EMDR-IGTP) on child survivors of the earthquakes that struck Umbria, a region of central Italy, on August 24th and on October 26th 2016. Three hundred and thirty-two children from the town of Norcia and nearby severely disrupted villages received 3 cycles of EMDR-IGTP. The Emotion Thermometers (ET-5) and the Children's Revised Impact of Event Scale (CRIES-13) were administered before (T0) and about 1 week after the conclusion of the third cycle (T3) of EMDR-IGTP...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29914197/-staphylococcus-aureus-isolates-from-bovine-mastitis-in-eight-countries-genotypes-detection-of-genes-encoding-different-toxins-and-other-virulence-genes
#16
Valentina Monistero, Hans Ulrich Graber, Claudia Pollera, Paola Cremonesi, Bianca Castiglioni, Enriqueta Bottini, Alejandro Ceballos-Marquez, Laura Lasso-Rojas, Volker Kroemker, Nicole Wente, Inge-Marie Petzer, Carlos Santisteban, Jeff Runyan, Marcos Veiga Dos Santos, Bruna Gomes Alves, Renata Piccinini, Valerio Bronzo, Mohamed Salah Abbassi, Meriam Ben Said, Paolo Moroni
Staphylococcus aureus is recognized worldwide as one of the major agents of dairy cow intra-mammary infections. This microorganism can express a wide spectrum of pathogenic factors used to attach, colonize, invade and infect the host. The present study evaluated 120 isolates from eight different countries that were genotyped by RS-PCR and investigated for 26 different virulence factors to increase the knowledge on the circulating genetic lineages among the cow population with mastitis. New genotypes were observed for South African strains while for all the other countries new variants of existing genotypes were detected...
June 17, 2018: Toxins
https://www.readbyqxmd.com/read/29913755/the-inter-and-intra-individual-variance-in-descending-pain-modulation-evoked-by-different-conditioning-stimuli-in-healthy-men
#17
Yuka Oono, Hongling Nie, Renata Lima Matos, Kelun Wang, Lars Arendt-Nielsen
Background and purpose Conditioned pain modulation (CPM) is a phenomenon in which pain is inhibited by heterotopic noxious stimulation. It is not known how the experimental condition affects the magnitude of the CPM response and the inter-and intra-individual variations. It is important to get the information of the test-retest reliability and inter-individual variations of CPM to apply CPM as a diagnostic tool or for screening analgesic compounds. This study evaluated (1) the magnitude of CPM, (2) the inter-individual coefficient of variation (inter-CV) and (3) the intra-individual coefficient of variation (intra-CV) to (A) different stimulus modalities to evoke CPM and (B) different assessment sites...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913481/deficiency-of-long-chain-polyunsaturated-fatty-acids-in-phenylketonuria-a-cross-sectional-study
#18
Sławomira Drzymała-Czyż, Łukasz Kałużny, Patrycja Krzyżanowska-Jankowska, Dariusz Walkowiak, Renata Mozrzymas, Jarosław Walkowiak
The etiology of altered blood fatty acid (FA) profile in phenylketonuria (PKU) is understood only partially. We aimed to determine whether FAs deficiency is dependent on the diet or metabolic disturbances. The study comprised 40 PKU patients (20 female, 20 male; aged 11 to 35 years; 12 children and 28 adults) and 40 healthy subjects (HS; 20 female, 20 male, aged 18 to 33 years). We assessed the profile of FAs (gas chromatography/mass spectrometry) and analyzed the 72-hour dietary recalls. The amount of C14:0, C16:0 and C16:1n-7, C18:1n-9 did not differ between the analyzed groups...
2018: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/29913360/spinal-cord-stimulation-in-the-treatment-of-complex-regional-pain-syndrome-type-1-is-trial-truly-required
#19
Erica Garbin Risson, Ana Paula Serpa, Jéssica Jacques Berger, Renata Fabiola Heil Koerbel, Andrei Koerbel
OBJECTIVE: Spinal cord stimulation has been proven highly effective in the treatment of Complex Regional Pain Syndrome (CRPS). The definitive implantation of a neurostimulator is usually preceded by a therapeutic test (trial), which has the purpose of identifying whether the patient would respond positively to neuromodulation or not. The present study aims to analyze the surgical results of spinal cord stimulation in type 1 CRPS patients who have not undergone trial. PATIENTS AND METHODS: From January 2011 to August 2017, 160 patients underwent implantation of spinal cord neurostimulator...
June 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29913229/inhaled-peppermint-rosemary-and-eucalyptus-essential-oils-do-not-change-spirometry-in-healthy-individuals
#20
Ferenc Köteles, Péter Babulka, Renáta Szemerszky, Zsuzsanna Dömötör, Szilvia Boros
Essential oils of herbal origin are widely used in the treatment of diseases of the upper and lower respiratory tract primarily due to their antibacterial and antiviral effects. Menthol, the major component of the essential oil of mint (Mentha) species, exhibits antispasmodic activity, which might result in improved lung function. In a randomized experiment, 106 healthy participants received nebulized peppermint, eucalyptus, or rosemary essential oil for 15 min or no treatment (control). None of the essential oils had an impact on the measured spirometric variables (forced vital capacity, peak expiratory flow, the ratio of the volume of air forcibly blown out in the first second to forced vital capacity)...
June 15, 2018: Physiology & Behavior
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