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https://www.readbyqxmd.com/read/28437823/-medicolegal-assessment-of-psychic-sequelae-after-minor-traumatic-events
#1
Bernhard Widder
The majority of medicolegal assessments in claimed psychic sequelae after accidents concerns minor traumatic events. In this case, the focus is on three questions: Was the event appropriate to cause a traumatic disturbance according to current psychiatric classification systems (especially current DSM-5)? Which psychical or physical initial injury can be proven beyond reasonable doubt ("full proof") according to German law? What is the impact of personality characteristics and competing life events in the development and maintenance of the mental disorder? Causality between mental disorders and minor traumatic events is to be confirmed especially in the case of persistent physical accident sequelae, but attention has to be paid to the differences in the various legal requirements...
April 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/28437818/-towards-a-rehabilitation-and-participation-oriented-psychotherapy
#2
Beate Muschalla, Jürgen Bengel, Matthias Morfeld, Ulrike Worringen
Mental disorders (such as recurrent mood disorders, personality disorders, or psychotic disorders) come along with enduring impairment in daily life activities. Therefore psychotherapeutic actions in inpatient or outpatient settings require a life-span and participation-oriented treatment perspective. Participation-oriented treatment aims at social and vocational integration in general life despite enduringly recurring or resting symptoms. According to the model of health problems offered by the International Classification of Functioning, Disability and Health, ICF (WHO, 2001), disability can be defined as context-dependent activity impairment due to illness...
April 24, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28437782/detection-of-renal-hypoxia-in-lupus-nephritis-using-blood-oxygen-level-dependent-mr-imaging-a-multiple-correspondence-analysis
#3
Huilan Shi, Tiekun Yan, Dong Li, Junya Jia, Wenya Shang, Li Wei, Zhenfeng Zheng
BACKGROUND/AIMS: Nephrologists have pursued ideal, dynamic and noninvasive methods for assessing renal function and disease progression. Blood oxygen level dependent (BOLD) imaging is a useful technique for assessing renal disease. This current study was performed to explore the correlation between the hypoxia iconographical index and renal pathological features in lupus nephritis. METHODS: Adult patients with lupus nephritis (LN) and healthy volunteers were recruited for this study...
April 5, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28437778/strengthening-governance-for-intertidal-ecosystems-requires-a-consistent-definition-of-boundaries-between-land-and-sea
#4
Stefanie M Rog, Carly N Cook
The protection of intertidal ecosystems is complex because they straddle both marine and terrestrial realms. This leads to inconsistent characterisation as marine and/or terrestrial systems, or neither. Vegetated intertidal ecosystems are especially complex to classify because they can have an unclear border with terrestrial vegetation, causing confusion around taxonomy (e.g., mangrove-like plants). This confusion and inconsistency in classification can impact these systems through poor governance and incomplete protection...
April 21, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28437759/correlation-of-technical-surgical-goals-to-the-gdi-and-investigation-of-post-operative-gdi-change-in-children-with-cerebral-palsy
#5
Christina Bickley, Judi Linton, Nancy Scarborough, Elroy Sullivan, Katy Mitchell, Douglas Barnes
AIM: The purpose of this study was to introduce a standardized set of surgical technical achievement goals (TAGs) as part of a comprehensive outcome assessment model for children with spastic cerebral palsy (CP) undergoing orthopaedic surgical intervention to improve gait. Examination of relationships of these surgical goals to the Gait Deviation Index (GDI) and use of two assessments in tandem provided a thorough picture of technical surgical outcomes. This study also investigated changes in GDI in children with spastic CP after surgery...
April 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28437757/abnormal-loading-and-functional-deficits-are-present-in-both-limbs-before-and-after-unilateral-knee-arthroplasty
#6
A J Metcalfe, C J Stewart, N J Postans, P R Biggs, G M Whatling, C A Holt, A P Roberts
Unilateral knee replacement is often followed by a contralateral replacement in time and the biomechanics of the other knee before and after knee replacement remains poorly understood. The aim of this paper is to distinguish the features of arthritic gait in the affected and unaffected legs relative to a normal population and to assess the objective recovery of gait function post-operatively, with the aim of defining patients at risk of poor post-operative function. Twenty patients with severe knee OA but no pain or deformity in any other lower limb joint were compared to twenty healthy subjects of the same age...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28437752/dna-repair-and-damage-pathways-in-breast-cancer-development-and-therapy
#7
REVIEW
Maryam Majidinia, Bahman Yousefi
DNA damage/repair constitutes several key pathways working in concert to eliminate DNA lesions and maintain genome stability and integrity. Defective components in DNA damage and repair machinery are an underlying cause for the development and progression of different types of cancers, and breast cancer is no exception. In this paper, we will briefly explain the importance of DNA damage and repair, introduce the current classification schemes for breast cancer, and review the known defects in the repair machinery that have been associated with the risk of breast cancer...
April 21, 2017: DNA Repair
https://www.readbyqxmd.com/read/28437634/convolutional-neural-network-regression-for-short-axis-left-ventricle-segmentation-in-cardiac-cine-mr-sequences
#8
Li Kuo Tan, Yih Miin Liew, Einly Lim, Robert A McLaughlin
Automated left ventricular (LV) segmentation is crucial for efficient quantification of cardiac function and morphology to aid subsequent management of cardiac pathologies. In this paper, we parameterize the complete (all short axis slices and phases) LV segmentation task in terms of the radial distances between the LV centerpoint and the endo- and epicardial contours in polar space. We then utilize convolutional neural network regression to infer these parameters. Utilizing parameter regression, as opposed to conventional pixel classification, allows the network to inherently reflect domain-specific physical constraints...
April 12, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28437615/experimental-demonstration-of-feature-extraction-and-dimensionality-reduction-using-memristor-networks
#9
Shinhyun Choi, Jong Hoon Shin, Jihang Lee, Patrick Sheridan, Wei D Lu
Memristors have been considered as a leading candidate for a number of critical applications ranging from non-volatile memory to non-Von Neumann computing systems. Feature extraction, which aims to transform input data from a high dimensional space to a space with fewer dimensions, is an important technique widely used in machine learning and pattern recognition applications. Here, we experimentally demonstrate that memristor arrays can be used to perform principal component analysis (PCA), one of the most commonly-used feature extraction techniques, through online, unsupervised learning...
April 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28437613/evaluating-the-role-of-multidrug-resistance-protein-3-mdr3-inhibition-in-predicting-drug-induced-liver-injury-using-125-pharmaceuticals
#10
Michael D Aleo, Falgun Shah, Kan He, Paul D Bonin, A David Rodrigues
The role of bile salt export protein (BSEP) inhibition in drug-induced liver injury (DILI) has been investigated widely, while inhibition of the canalicular multidrug resistant protein 3 (MDR3) has received less attention. This transporter plays a pivotal role in secretion of phospholipids into bile and functions coordinately with BSEP to mediate the formation of bile acid-containing biliary micelles. Therefore, inhibition of MDR3 in human hepatocytes was examined across 125 drugs (70 of Most- and 55 of No-DILI-concern)...
April 24, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28437595/natural-history-and-predictors-of-progression-to-sj%C3%A3-gren-s-syndrome-among-participants-of-the-sicca-registry
#11
Caroline H Shiboski, Alan N Baer, Stephen C Shiboski, Mi Lam, Stephen Challacombe, Hector E Lanfranchi, Morten Schiødt, Penelope Shirlaw, Muthiah Srinivasan, Hisanori Umehara, Frederick B Vivino, Esen Akpek, Vatinee Bunya, Cristina F Vollenweider, John S Greenspan, Troy E Daniels, Lindsey A Criswell
BACKGROUND/PURPOSE: To explore changes in the phenotypic features of Sjoögren's syndrome (SS), and in SS status among participants in the Sjoögren's International Collaborative Clinical Alliance (SICCA) registry over a 2 to 3-year interval. METHODS: All participants in the SICCA registry who were found to have any objective measures of salivary hypofunction, dry eye, focal lymphocytic sialadenitis in minor salivary gland biopsy, or anti-SSA/B antibodies, were recalled over a window of 2 to 3 years after their baseline examinations to repeat all clinical examinations and specimen collections to determine whether there was any change in phenotypic features and in SS status...
April 24, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28437577/high-gene-flow-despite-opposite-chirality-in-hybrid-zones-between-enantiomorphic-door-snails
#12
Eva L Koch, Marco T Neiber, Frank Walther, Bernhard Hausdorf
We studied differentiation and gene flow patterns between enantiomorphic door-snail species in two hybrid zones in the Bucegi Mountains (Romania) to investigate the effects of intrinsic barriers (complications in copulation) and extrinsic selection by environmental factors. A mitochondrial gene tree confirmed the historical separation of the examined populations into the dextral Alopia livida and the sinistral Alopia straminicollis in accordance with the morphological classification, but also indicated gene flow between the species...
April 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28437514/a-retrospective-study-on-possible-predictive-factors-for-long-term-temporomandibular-joint-degeneration-and-impaired-mobility-in-juvenile-arthritis-patients
#13
Stanimira I Kalaykova, Adriaan T Klitsie, Corine M Visscher, Machiel Naeije, Frank Lobbezoo
AIMS: To determine possible predictive factors for long-term temporomandibular joint (TMJ) degeneration and dysfunction in juvenile idiopathic arthritis (JIA) patients. METHODS: A total of 94 patients (77% female) who had received a JIA diagnosis in an outpatient rheumatology clinic from 1993 to 1994 at a mean ± standard deviation age of 8.3 ± 4.53 years were included in the study. At inclusion, TMJ status regarding condylar degeneration was assessed orthopantomographically and given a Rohlin and Petersson score of 0 or ≥ 1...
April 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28437490/the-diagnosis-and-initial-treatment-of-patellofemoral-disorders
#14
Alan C Merchant, John P Fulkerson, Wayne Leadbetter
Our purpose is to provide simple guidelines for the diagnosis and early care of patellofemoral disorders. Any clinician who treats knee problems, including family practitioners, rheumatologists, orthopedic surgeons, or physical therapists, must know how to make the correct diagnosis, or at least a presumptive diagnosis, at the initial visit. This can avoid unneeded and costly tests, ineffective treatment, and even damaging exercises and unnecessary surgery. The diagnosis of patellofemoral disorders is confusing because they can have many causes...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28437347/effect-of-coronal-scoliotic-curvature-on-sagittal-spinal-shape-analysis-of-parameters-in-mature-adolescent-scoliosis-patients
#15
Jae-Young Hong, Keon-Woo Kim, Seung-Woo Suh, Si-Young Park, Jae-Hyuk Yang
STUDY DESIGN: A radiographic analysis with scoliosis patients. OBJECTIVES: To analyze correlations between sagittal spinal alignment and coronal scoliotic curvature. SUMMARY OF BACKGROUND DATA: Sagittal spinal alignment and scoliosis may have a significant relationship, and schematic analysis is needed. METHODS: The study group was comprised of 163 patients with adolescent idiopathic scoliosis. Subjects underwent anteroposterior and lateral radiographs of the whole spine including hip joints...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437319/quality-of-antiepileptic-treatment-among-older-medicare-beneficiaries-with-epilepsy-a-retrospective-claims-data-analysis
#16
Maria Pisu, Joshua Richman, Kendra Piper, Roy Martin, Ellen Funkhouser, Chen Dai, Lucia Juarez, Jerzy P Szaflarski, Edward Faught
BACKGROUND: Enzyme-inducing antiepileptic drugs (EI-AEDs) are not recommended for older adults with epilepsy. Quality Indicator for Epilepsy Treatment 9 (QUIET-9) states that new patients should not receive EI-AEDs as first line of treatment. In light of reported racial/ethnic disparities in epilepsy care, we investigated EI-AED use and QUIET-9 concordance across major racial/ethnic groups of Medicare beneficiaries. RESEARCH DESIGN: Retrospective analyses of 2008-2010 Medicare claims for a 5% random sample of beneficiaries 67 years old and above in 2009 augmented for minority representation...
April 21, 2017: Medical Care
https://www.readbyqxmd.com/read/28437318/results-of-macular-hole-surgery-evaluation-based-on-the-international-vitreomacular-traction-study-classification
#17
Laura Liu, Ijilmurun Enkh-Amgalan, Nan-Kai Wang, Lan-Hsin Chuang, Yen-Po Chen, Yih-Shiou Hwang, Chee-Jen Chang, Kuan-Jen Chen, Wei-Chi Wu, Tun-Lu Chen, Chi-Chun Lai
PURPOSE: To evaluate the differences in anatomical and visual function changes after macular hole (MH) surgery using the International Vitreomacular Traction Study classification. METHODS: Patients who underwent vitrectomy and blood-assisted internal limiting membrane peeling because of MHs were enrolled in the present study. The patients were divided into three groups according to the sizes of their MHs (small: ≤250 μm, medium: >250 μm and ≤400 μm, and large: >400 μm)...
April 20, 2017: Retina
https://www.readbyqxmd.com/read/28437266/gelfoam-interposition-minimizes-risk-of-fistula-and-postoperative-bleeding-in-modified-furlow-palatoplasty
#18
Jing Li, Patrick A Gerety, James Johnston, Jesse A Taylor
Failure to accomplish a tension-free, watertight closure predisposes the palatoplasty patient to fistula formation. Perioperative bleeding also places the patient at risk for adverse airway events (AAE). This study introduces the incorporation of a hemostatic gelatin sponge (Gelfoam) into layered palatoplasty to minimize adverse postoperative bleeding and fistula formation. A retrospective chart review was performed to identify subjects who underwent Furlow palatoplasty with insertion of Gelfoam from 2010 to 2015...
April 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28437154/prediction-of-relapse-from-hyperthyroidism-following-antithyroid-medication-withdrawal-using-technetium-thyroid-uptake-scanning
#19
Manouchehr Nakhjavani, Soraya Abdollahi, Saeed Farzanefar, Mohammadtagi Abousaidi, Alireza Esteghamati, Maryam Naseri, Mohamad Eftekhari, Mehrshad Abbasi
OBJECTIVE: Technetium thyroid uptake (TTU) is not inhibited by antithyroid drugs (ATD) and reflects the degree of thyroid stimulation. We intended to predict the relapse rate from hyperthyroidism based on TTU measurement. METHODS: Out of 44 initially enrolled subjects, 38 patients aged 41.6 ± 14.6 with Graves disease (duration: 84 ± 78 months) completed the study. TTU was performed with 40-second imaging of the neck and mediastinum 20 minutes after injection of 1 mCi technetium-99m pertechnetate...
April 2, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28436910/discovering-the-relationship-between-generalization-and-uncertainty-by-incorporating-complexity-of-classification
#20
Xi-Zhao Wang, Ran Wang, Chen Xu
The generalization ability of a classifier learned from a training set is usually dependent on the classifier's uncertainty, which is often described by the fuzziness of the classifier's outputs on the training set. Since the exact dependency relation between generalization and uncertainty of a classifier is quite complicated, it is difficult to clearly or explicitly express this relation in general. This paper shows a specific study on this relation from the viewpoint of complexity of classification by choosing extreme learning machines as the classification algorithms...
April 24, 2017: IEEE Transactions on Cybernetics
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