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Hyperpigmentation

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https://www.readbyqxmd.com/read/28341693/minocycline-induced-skin-hyperpigmentation
#1
Jonathan Alpern, Anjum Kaka
No abstract text is available yet for this article.
March 24, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28339809/minocycline-induced-hyperpigmentation
#2
H Matsuura, A Senoo, M Saito, Y Hamanaka
No abstract text is available yet for this article.
February 28, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28333854/presumed-retinal-pigment-epithelium-tumor-originating-from-unilateral-retinal-pigment-epithelium-dysgenesis
#3
Orly Gal-Or, Paul T Finger, Yale L Fisher, Lawrence A Yannuzzi, K Bailey Freund
PURPOSE: To describe a patient with a presumed retinal pigment epithelium (RPE) tumor originating from unilateral RPE dysgenesis. METHODS: Case report. RESULTS: A 30-year-old woman with an unremarkable medical and ocular history was referred for an evaluation of progressive central metamorphopsia in her left eye. Visual acuity was 20/20 in her right eye and 20/25 in her left eye. Funduscopic examination of the left eye revealed an elevated mass within an area of unilateral RPE dysgenesis showing hyperpigmentation and hypopigmentation with scalloped margins...
March 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28333105/anti-melanogenic-properties-of-greek-plants-a-novel-depigmenting-agent-from-morus-alba-wood
#4
Eliza Chaita, George Lambrinidis, Christina Cheimonidi, Adamantia Agalou, Dimitris Beis, Ioannis Trougakos, Emmanuel Mikros, Alexios-Leandros Skaltsounis, Nektarios Aligiannis
In therapeutic interventions associated with melanin hyperpigmentation, tyrosinase is regarded as a target enzyme as it catalyzes the rate-limiting steps in mammalian melanogenesis. Since many known agents have been proven to be toxic, there has been increasing impetus to identify alternative tyrosinase inhibitors, especially from natural sources. In this study, we investigated 900 extracts from Greek plants for potential tyrosinase inhibitive properties. Among the five most potent extracts, the methanol extract of Morus alba wood (MAM) demonstrated a significant reduction in intracellular tyrosinase and melanin content in B16F10 melanoma cells...
March 23, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28329621/facial-pigmentation-with-demodex-mite-a-mere-coincidence-or-an-association
#5
Betul Sereflican, Bengu Tuman, Cetin Boran, Nadir Goksugu, Ali Haydar Parlak, Mualla Polat
Demodex mites may induce inflammatory cutaneous reactions such as papulopustular rosacea and demodex folliculitis; both may lead to post inflammatory pigmentation. A 59-year-old man presented with an asymptomatic, hyperpigmented plaque on his face. Histological and clinical findings displayed Riehl-like facial pigmentation. Multiple demodex mites at the follicular infundibulum in the biopsy material were remarkable. There are limited publications about demodex-associated pigmentation. We report this case to point out that various hyperpigmentation disorders may occur simultaneously with demodex mites...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328709/the-clinical-and-histological-effect-of-a-low-fluence-q-switched-1-064-nm-neodymium-yttrium-aluminum-garnet-laser-for-the-treatment-of-melasma-and-solar-lentigo-in-asians-prospective-randomized-and-split-face-comparative-study
#6
Chikako Kaminaka, Fukumi Furukawa, Yuki Yamamoto
BACKGROUND: The low-fluence Q-switched 1,064-nm neodymium:yttrium-aluminum-garnet laser (QSNYL) is popular for melasma treatment among Asians. OBJECTIVE: This study was to evaluate the clinical and histological effects of the low-fluence QSNYL for treatment of melasma and solar lentigo. MATERIALS AND METHODS: In this randomized split-face clinical study, 22 patients with melasma or solar lentigo received low-fluence QSNYL weekly for 10 sessions on one cheek...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28319270/evaluation-of-a-transparent-perfluorodecalin-infused-patch-as-an-adjunct-to-laser-assisted-tattoo-removal-a-pivotal-trial
#7
Brian S Biesman, Cara Costner
BACKGROUND AND OBJECTIVE: Laser-assisted treatment of tattoos is well recognized to produce opaque epidermal whitening that prevents multiple sequential passes during a single treatment session. The amount of epidermal whitening produced in association with the procedure can be minimized by topical application of perfluorodecalin (PFD), which is an optical clearing agent. This pivotal trial assessed the ability of a transparent PFD-infused patch used in conjunction with a Q-switched nanosecond laser in the treatment of tattoos to permit multiple laser passes during a single 5 minute treatment session in comparison to the number of passes that could be completed using conventional treatment of the tattoo with the laser alone...
March 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28314711/validating-the-herdoo2-rule-to-guide-treatment-duration-for-women-with-unprovoked-venous-thrombosis-multinational-prospective-cohort-management-study
#8
Marc A Rodger, Gregoire Le Gal, David R Anderson, Jeannot Schmidt, Gilles Pernod, Susan R Kahn, Marc Righini, Patrick Mismetti, Clive Kearon, Guy Meyer, Antoine Elias, Tim Ramsay, Thomas L Ortel, Menno V Huisman, Michael J Kovacs
Objective To prospectively validate the HERDOO2 rule (Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years), which states that women with none or one of the criteria can safely discontinue anticoagulants after short term treatment.Design Prospective cohort management study.Setting 44 secondary or tertiary care centres in seven countries.Participants Of 3155 consecutive eligible participants with a first unprovoked venous thromboembolism (VTE, proximal leg deep vein thrombosis or pulmonary embolism) who completed 5-12 months of short term anticoagulant treatment, 370 declined to participate, leaving 2785 enrolled participants...
March 17, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28300929/oculoectodermal-syndrome-twentieth-described-case-with-new-manifestations
#9
Daniela de Almeida Figueiras, Deborah Maria de Castro Barbosa Leal, Valter Kozmhinsky, Marina Coutinho Domingues Querino, Marina Genesia da Silva Regueira, Maria Gabriela de Morais Studart
Oculoectodermal syndrome is a rare disease characterized by the association of aplasia cutis congenita, epibulbar dermoids, and other abnormalities. This report describes the twentieth case of the disease. We report a 4-year-old female child who presented with the classical features of the syndrome: aplasia cutis congenita and epibulbar dermoids. Our case expands the clinical spectrum of the disease to include: diffuse hyperpigmentation (some following the Blaschko´s lines); hypopigmented skin areas on the trunk; arachnoid cyst on the right fronto-parietal border; rounded left side of the hippocampus; and dermoid cyst underlying the bulb-medullary transition...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300902/laptop-computer-induced-erythema-ab-igne-a-new-presentation-of-an-old-disease
#10
Ana Gabriela Salvio, Adauto Jose Nunes, Dora Patricia Ramirez Angarita
Erythema ab igne is a condition characterized by skin changes due to chronic exposure to moderate temperature. We describe a female patient with continuous use of a laptop computer on exposed legs for 6 months and consequent development of reticulated hyperpigmentation at the area. Histopathological examination revealed epidermal atrophy, collagen fragmentation, and vacuolar changes in the basal layer, among other signs. We consider this case to be a modern cause of erythema ab igne.
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300885/chemical-leukoderma-induced-by-dimethyl-sulfate
#11
Maya Valeska Gozali, Jia-An Zhang, Fei Yi, Bing-Rong Zhou, Dan Luo
Chemical leukoderma occurs due to the toxic effect of a variety of chemical agents. Mechanisms include either destruction or inhibition of melanocytes. We report two male patients (36 and 51 years old) who presented with multiple hypopigmented macules and patches on the neck, wrist, and legs after exposure to dimethyl sulfate in a chemical industry. Physical examination revealed irregular depigmentation macules with sharp edges and clear hyperpigmentation around the lesions. History of repeated exposure to a chemical agent can help the clinical diagnosis of chemical leukoderma...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300439/evaluation-of-the-efficacy-of-cryosurgery-in-patients-with-sebaceous-hyperplasia-of-the-face
#12
Hatice Ataş, Müzeyyen Gönül
BACKGROUND: Cryosurgery is an effective treatment for sebaceous hyperplasia, but there have been few clinical studies. OBJECTIVES: The aim of this study was to evaluate the efficacy and safety of cryosurgery in the treatment of sebaceous hyperplasia. METHODS: Cryosurgery was performed 6 times, at 2-week intervals, with liquid nitrogen, and evaluated in 40 patients with 517 lesions ranging from 2 to 9 mm over the forehead, cheeks, and chin...
December 1, 2016: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28300437/botanicals-with-dermatologic-properties-derived-from-first-nations-healing
#13
Sophia Colantonio, Jason K Rivers
INTRODUCTION: Plants and algae have played a central role in the treatment of skin conditions in both traditional First Nations healing and in modern dermatology. The objective of this study was to examine the evidence supporting the dermatological use of seaweed, witch hazel, bearberry, and mayapple. METHODS: Four plants and algae used in traditional First Nations treatments of skin disease were selected based on expert recommendations. Several databases were searched to identify relevant citations without language restrictions...
December 1, 2016: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28299301/solution-of-azelaic-acid-20-resorcinol-10-and-phytic-acid-6-versus-glycolic-acid-50-peeling-agent-in-the-treatment-of-female-patients-with-facial-melasma
#14
Gita Faghihi, Azam Taheri, Zabihollah Shahmoradi, Mohammad Ali Nilforoushzadeh
BACKGROUND: Melasma, a common acquired disorder of hyperpigmentation, especially in women, is often resistant to therapy. This study was aimed to evaluate the efficacy and safety of azelaic acid, resorcinol and phytic acid solution in chemical peeling of melasma in comparison to 50% glycolic acid. MATERIALS AND METHODS: This clinical trial was performed, on 42 female patients with bilateral melasma. Severity of melasma was assessed by melasma area and severity index (MASI)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28296736/dermoscopic-features-of-livedoid-vasculopathy
#15
Stephen Chu-Sung Hu, Gwo-Shing Chen, Chi-Ling Lin, Yang-Chun Cheng, Yung-Song Lin
Livedoid vasculopathy (atrophie blanche) is a form of thrombotic vasculopathy. It is characterized by small ulcers that become crusted, and heal after several months to produce white atrophic scars. The most commonly affected sites are the lower legs, in particular the dorsum of the feet and ankles. To date, the dermoscopic features of livedoid vasculopathy have not been clearly described in the literature. In this observational study, we sought to evaluate the dermoscopic patterns of livedoid vasculopathy and determine whether the dermoscopic features are associated with certain histopathological characteristics...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28290623/sequential-monitoring-of-pigmented-lesions-during-dabrafenib-treatment-a-prospective-study-and-a-literature-overview
#16
Emi Dika, Martina Lambertini, Pier A Fanti, Bianca M Piraccini, Carlotta Gurioli, Giulia M Ravaioli, Marco A Chessa, Alessandro Traniello Gradassi, Barbara Melotti, Francesca Sperandi, Annalisa Patrizi
BACKGROUND: Targeted therapies in melanoma have shown clinical benefit in incrementing the overall survival of metastatic patients. However, cutaneous adverse events have been frequently associated with these drugs. METHODS: We report our experience in the management of patients treated with dabrafenib for metastatic melanoma, focusing on the monitoring of pigmented lesions. Dermatologic evaluation was performed during the first visit, at the start of each treatment and subsequently after every four weeks...
March 14, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28283015/-cutaneous-larva-migrans-in-turkey-an-imported-case-report
#17
Meliha Çağla Sönmezer, Şebnem Erdinç, Necla Tülek, Cahit Babür, Ayşe Büyükdemirci, Tuba İlgar, Günay Ertem
Cutaneous larva migrans (CLM) is a parasitic infection most commonly found in tropical and subtropical areas. However, with the ease and increase of foreign travel to many countries around the world, the infection is not limited to these areas. CLM is an erythematous, serpiginous infection with skin eruption caused by percutaneous penetration of the larvae to the skin. In this report, a case diagnosed as imported CLM after an Amazon trip and treated with albendazole was presented. A 36 year-old male patient admitted to infectious diseases clinic with intense itching, erythematous, raised, streaklike serpiginious eruptionand some redness at bilateral foot especially at the right foot for about one week...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28280707/oral-manifestations-and-their-correlation-to-baseline-cd4-count-of-hiv-aids-patients-in-ghana
#18
Paul Frimpong, Emmanuel Kofi Amponsah, Jacob Abebrese, Soung Min Kim
OBJECTIVES: Acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). People with AIDS are much more vulnerable to infections, including opportunistic infections and tumors, than people with a healthy immune system. The objective of this study was to correlate oral lesions associated with HIV/AIDS and immunosuppression levels by measuring clusters of differentiation 4 (CD4) cell counts among patients living in the middle western regions of Ghana...
February 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28276331/answer-to-photo-quiz-hyperpigmentation-of-the-tongue-in-a-patient-receiving-chemotherapy
#19
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/28276330/hyperpigmentation-of-the-tongue-in-a-patient-receiving-chemotherapy
#20
F Tous-Romero, S Burillo-Martínez, V Velasco-Tamariz, L Maroñas-Jiménez
No abstract text is available yet for this article.
March 2017: Netherlands Journal of Medicine
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