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https://www.readbyqxmd.com/read/29329134/asymptomatic-acquired-facial-hyperpigmentation
#1
Mayra B C Maymone, Jonathan D Ho, Dana Saadeh, Jag Bhawan, Neelam A Vashi
No abstract text is available yet for this article.
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29328527/pruritic-papulovesicular-dermatosis-with-reticular-hyperpigmentation
#2
Victor Olsavszky, Cyrill Géraud
No abstract text is available yet for this article.
January 12, 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29325984/minimally-invasive-repair-of-pectus-carinatum
#3
Mustafa Yuksel, Tunc Lacin, Nezih Onur Ermerak, Esra Yamansavci Sirzai, Bihter Sayan
BACKGROUND: The second most common deformity of the anterior chest wall, pectus carinatum, is a diverse deformity that has been largely managed using open techniques. This study reviews clinical experience with a newly designed bar for minimally invasive repair of pectus carinatum. METHODS: We reviewed the records of all patients recorded in our Chest Wall Deformities Clinical Database. Between January 2006 and November 2016, minimally invasive repair of pectus carinatum was performed in 172 patients...
January 9, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29325793/mucocutaneous-hyperpigmentation
#4
Francisco Galeano-Valle, Lucía Higuera-Cabañes
No abstract text is available yet for this article.
January 8, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29324427/lemons-in-the-arizona-sunshine-the-effects-of-furocoumarins-leading-to-phytophotodermatitis-and-burn-like-injuries
#5
Marc R Matthews, Joel C VanderVelde, Daniel M Caruso, Kevin N Foster
INTRODUCTION: Phytophototoxic dermatitis is a strong phototoxic reaction to ultraviolet A (UV-A) radiation exposure after cutaneous contact with citrus fruit containing furocoumarins, leading to skin injury. At the Arizona Burn Center (Phoenix, AZ), the majority of these injuries are managed in the outpatient setting. CASE REPORT: The authors present a pediatric admission for burn-like injuries following prolonged cutaneous exposure to lemons while playing in the Arizona sunshine...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29320596/double-blind-placebo-controlled-evaluation-of-a-novel-skin-lightening-agent
#6
James M Spencer, Julianna Accioly, Neal Kitchen
Melasma remains a troubling problem for physicans and patients alike. It is a chronic irregular, symmetric hyperpigmentation seen most often in women. In this study, a unique combination of ingredients with non-irritating properties was tested for treatment of melasma. In a double blind, placebo controlled, split face trial, 17 patients with melasma were treated on one half of the face, left or right, while the other received placebo control. All patients used sunscreen on both sides. Measurement with a colorimeter (Mexameter) was taken at baseline and after 8 weeks of daily use...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320586/safety-and-efficacy-of-a-1550nm-1927nm-dual-wavelength-laser-for-the-treatment-of-photodamaged-skin
#7
Vic A Narurkar, Tina S Alster, Eric F Bernstein, Tina J Lin, Anya Loncaric
<p>BACKGROUND: Fractional photothermolysis (FP) is a popular treatment option for photodamaged skin and addresses shortcomings of ablative skin resurfacing and nonablative dermal remodeling. Previous studies have demonstrated that FP using the 1550nm wavelength has led to improvement of ultrastructural changes and clinical effects associated with photodamaged skin in the deeper dermal structures, while treatment with the 1927nm wavelength has shown clinical effects in the superficial dermis. Both wavelengths produce precise microscopic treatment zones (MTZs) in the skin...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320585/liposuction-of-the-neck-low-incidence-of-nerve-injury-and-other-complications-in-987-patients
#8
Loeb Habbema, Jennifer C Tang, Gerhard Sattler, C William Hanke
<p>The neck is one of the most common areas treated by liposuction. Neck liposuction decreases fat volume, causes skin contraction, and restores a more youthful appearance. We present a large case series (n=987) performed by three dermatologic surgeons. Five patients developed temporary post-operative marginal mandibular dysfunction, one patient had submandibular gland ptosis and one patient had arterial bleeding. Seroma, skin necrosis, scarring, and hyperpigmentation did not occur following neck liposuction...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320400/posidonia-oceanica-l-delile-ethanolic-extract-modulates-cell-activities-with-skin-health-applications
#9
Laura Cornara, Giulia Pastorino, Barbara Borghesi, Annalisa Salis, Marco Clericuzio, Carla Marchetti, Gianluca Damonte, Bruno Burlando
Seagrasses are high plants sharing adaptive metabolic features with both terrestrial plants and marine algae, resulting in a phytocomplex possibly endowed with interesting biological properties. The aim of this study is to evaluate the in vitro activities on skin cells of an ethanolic extract obtained from the leaves of Posidonia oceanica (L.) Delile, family Potamogetonaceae, herein named Posidonia ethanolic extract (PEE). PEE showed high radical scavenging activity, high phenolic content, and resulted rich in chicoric acid, as determined through HPLC-MS analysis...
January 10, 2018: Marine Drugs
https://www.readbyqxmd.com/read/29316744/anti-pigmentation-effect-of-phellinus-linteus-fermented-eight-traditional-crude-herbalextracts-in-brown-guinea-pigsof-ultraviolet-b-uvb-induced-hyperpigmentation
#10
Hee-Young Ahn, Young-Moo Choo, Young-Su Cho
We have previously found that mycelia culture broth of eight kinds of traditional herbal extracts fermented with Phellinus linteus (previously named as 8-HsPLCB) not only inhibited melanin and tyrosinase activity, but also reduced the contents of melanogenesis-related proteins including tyrosinase and microphthalmia-associated transcription factor (MITF) in 3- isobutyl-1-methylxanthine (IBMX)-stimulated B16F0 melanoma cells. For a further study, the effect of 8-HsPLCB against skin pigmentation in brown guinea pigs of ultraviolet B (UVB)-induced hyperpigmentation was investigated...
January 11, 2018: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29314292/examination-of-the-melanocytes-of-the-nevus-of-ota-with-in-vivo-reflectance-confocal-microscopy-15-cases
#11
Christoph Grechenig, Elisa Cinotti, Bruno Labeille, Gerald Langmann, Jean Luc Perrot, Olivia Schatz, Lisa Tarmann, Andreas Wedrich, Werner Wackernagel, Iris Zalaudek, Johannes Haybaeck, Christoph Schwab
The Nevus of Ota (NO) is a bluish or greyish hyperpigmentation caused by an accumulation of dermal melanocytes that typically extend to the innervated parts of the ophthalmic and maxillary divisions of the trigeminal nerve, involving the facial skin, the uvea, the iris and the sclera (Figure 1). This article is protected by copyright. All rights reserved.
January 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29311485/evaluation-of-antimelanogenic-activity-and-mechanism-of-galangin-in-silico-and-in-vivo
#12
Ki Wung Chung, Hyeong Oh Jeong, Eun Kyeong Lee, Su Jeong Kim, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon
Abnormal pigmentation owing to excessive melanin synthesis can result in serious problems such as freckles, age-spots, and melanoma. Tyrosinase inhibitors have been an interesting target for the treatment of hyperpigmentation because tyrosinase is the rate-limiting enzyme in melanin synthesis. The screening for strong tyrosinase inhibitors led to the finding of the flavonoid galangin, which showed notable inhibitory effects on mushroom tyrosinase. The IC50 value of galangin (3.55±0.39 µM) was lower than that of kojic acid (48...
2018: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29311047/cutaneous-drug-reactions-chemotherapy-induced-hyperpigmentation
#13
Ignacio Hernández-Aragüés, Ofelia Baniandrés-Rodríguez, Pedro Tiago Vilas-Boas, Elena Conde-Montero, Ricardo Suárez-Fernández
No abstract text is available yet for this article.
December 1, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29302212/ethyl-linoleate-inhibits-%C3%AE-msh-induced-melanogenesis-through-akt-gsk3%C3%AE-%C3%AE-catenin-signal-pathway
#14
Gyeong-A Ko, Somi Kim Cho
Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent. In this study, we investigated the effect of ethyl linoleate on the melanogenesis and the mechanism underlying its action on melanogenesis in B16F10 murine melanoma cells. Our results revealed that ethyl linoleate significantly inhibited melanin content and intracellular tyrosinase activity in α-MSH-induced B16F10 cells, but it did not directly inhibit activity of mushroom tyrosinase...
January 2018: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/29297970/evaluation-of-carboxytherapy-and-platelet-rich-plasma-in-treatment-of-periorbital-hyperpigmentation-a-comparative-clinical-trial
#15
Eman Nofal, Reham Elkot, Ahmad Nofal, Fatma Eldesoky, Shymaa Shehata, Maha Sami
BACKGROUND: Management of periorbital hyperpigmentation (POH) is still a therapeutic challenge. Although different therapeutic modalities are available, the outcomes of most of them are unsatisfactory. OBJECTIVES: To investigate and compare the efficacy and safety of two new modalities in the treatment of POH; the platelet rich plasma (PRP) and the carboxytherapy. SUBJECTS AND METHODS: The study included 30 patients with POH. Every patient was subjected to seven intradermal injections of PRP on the left periorbital area with 2 week intervals between sessions and carboxytherapy on the right area with 1 week interval apart...
January 3, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29288102/a-split-face-single-blinded-randomized-controlled-comparison-of-alexandrite-755-nm-picosecond-laser-vs-alexandrite-755-nm-nanosecond-laser-in-the-treatment-of-acquired-bilateral-nevus-of-ota-like-macules-abnom
#16
Wenyou Yu, Jiafang Zhu, Wenxin Yu, Dongze Lyu, Xiaoxi Lin, Zhen Zhang
BACKGROUND: Q-switched alexandrite lasers (QSAL) have been used for the treatment of acquired bilateral nevus of Ota-like macules (ABNOM). Currently, picosecond alexandrite laser (PSAL) pulses have become available for pigmentary disorders. However, no studies have compared PSAL and QSAL in the treatment of ABNOM. OBJECTIVE: To compare the efficacy and safety of a PSAL and a QSAL in the treatment of ABNOM. METHODS: Each patient (n = 30) received three treatments at six-month intervals...
December 26, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29287748/drug-associated-hyperpigmentation-of-the-oral-mucosa-report-of-four-cases
#17
REVIEW
Konstantinos I Tosios, Eleni-Marina Kalogirou, Alexandra Sklavounou
OBJECTIVE: The aim of this study was to describe 4 patients with oral mucosa hyperpigmentation associated with 4 drug classes and to review the relevant literature. STUDY DESIGN: Two patients under imatinib and hydroxychloroquine treatment exhibited diffuse palatal hyperpigmentation and 2 patients treated with minocycline and golimumab showed multifocal pigmented macules. In all cases, biopsy was performed. RESULTS: Microscopically, in all cases, there was no increase in the number of melanocytes in the epithelium, and pigment granules were present in the lamina propria...
November 3, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29283460/a-novel-scale-for-measurement-of-acquired-dermal-macular-hyperpigmentation-adhm-severity
#18
Keshavamurthy Vinay, Garima Dabas, Davinder Parsad, Sendhil Kumaran Muthu
Acquired dermal macular hyperpigmentation (ADMH) is a hypernym which includes lichen planus pigmentosus (LPP), Riehl's melanosis (RM), pigmented contact dermatitis (PCD) and erythema dyschromicum perstans (EDP). There is considerable overlap between the clinical and histopathological features of these conditions. Despite affecting a large number of patients, there is no validated quantitative scale for LPP/EDP/RM/PCD/ADMH. This article is protected by copyright. All rights reserved.
December 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29273144/opsin3-a-link-to-visible-light-induced-skin-pigmentation
#19
Subba Rao Setty
Skin pigmentation is primarily dependent on melanogenesis, a physiological process that occurs in melanosomes of melanocytes. Solar radiation modulates pigmentation through variety of signaling pathways, but the mechanism of visible light-induced hyperpigmentation remains uncharacterized. Passeron's group recently reported that visible light stimulates opsin3-regulated calcium-dependent microphthalmia-associated transcription factor activation that increases pigment gene expression and that it also causes the clustering of melanogenic enzymes...
January 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29246874/exploration-of-surface-plasmon-resonance-for-yam-tyrosinase-characterization
#20
Tabassum Mulla, Sushama Patil, Jyoti Jadhav
Tyrosinase is a ubiquitous enzyme in nature. It catalyzes the reaction in melanin formation. In this investigation, tyrosinase from a Yam tuber (Amorphophallus paeoniifolius) was extracted and purified by ultra-centrifugal filtration followed by ion exchange chromatography. The purified enzyme was obtained with purification fold of 12.65and specific activity of 60.25U/mg. The molecular weight of purified enzyme was confirmed to be 45kDa by SDS-PAGE. The enzyme activity was optimal at pH 6 and 30°C with Km 10mM...
December 12, 2017: International Journal of Biological Macromolecules
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