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https://www.readbyqxmd.com/read/29351088/fraction-variant-beam-orientation-optimization-for-non-coplanar-imrt
#1
Daniel O'Connor, Victoria Yu, Dan Nguyen, Dan Ruan, Ke Sheng
Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously optimizes non-coplanar beam angles for all fractions, yielding a fraction-variant (FV) treatment plan. Beam angles are selected by solving a multi-fraction fluence map optimization problem involving 500-700 candidate beams per fraction, with an additional group sparsity term that encourages most candidate beams to be inactive...
January 19, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29349981/-clinical-results-in-early-and-mid-term-of-using-the-s-rom-femoral-stem-in-revision
#2
Shang Piao, Yong-Gang Zhou, Yin-Qiao Du, Hai-Yang Ma, Jing-Yang Sun, Zhi-Sen Gao, Ya-Wen Peng, Wen-Ming Wu
OBJECTIVE: To investigate and the clinical effect of S-ROM modular stem in femur reconstruction in hip revision arthroplasty. METHODS: From January 2008 to January 2016, 21 patients received revision hip arthroplasties using S-ROM stems. There were 5 males and 16 females with an average of 48.33 years old(range, 29 to 73 years old). There were 13 cases caused by aseptic loosening, 4 cases by infection, 2 cases by nonunion of sub-tuberosity osteotomy, 1 case for repeated dislocation, 1 case for traumatic great trochanter fracture...
April 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29344033/investigating-the-prevalence-of-low-bone-mass-in-children-of-southern-iran-and-its-associated-factors
#3
Forough Saki, Gholamhossein Ranjbar Omrani, Marjan Jeddi, Marzie Bakhshaieshkaram, Mohammad Hossein Dabbaghmanesh
Background: Improving peak bone mass and bone strength in the first years of life and enhancing it during young adulthood could prevent osteoporosis and fractures in the last years of life. We evaluated the prevalence of low bone mass in the lumbar and femoral neck and its associated factors in southern Iranian children. Methods: This is a cross-sectional study on healthy Iranian children aged 9 - 18 years old during 2011 - 2012. Dual energy X-ray absorptiometry (DEXA) was used for measuring bone mineral density (BMD)...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29343264/associations-between-circulating-adipokines-and-bone-mineral-density-in-patients-with-knee-osteoarthritis-a-cross-sectional-study
#4
Juan Wu, Jianhua Xu, Kang Wang, Qicui Zhu, Jingyu Cai, Jiale Ren, Shuang Zheng, Changhai Ding
BACKGROUND: Associations between adipokines and bone mineral density (BMD) in knee osteoarthritis (OA) remain indistinct. The aim of this study was to investigate the cross-sectional associations between serum levels of adipokines and BMD in patients with knee OA. METHODS: This study included 164 patients with symptomatic knee OA from the Anhui Osteoarthritis study. Serum levels of leptin, adiponectin, and resistin were measured using an enzyme-linked immunosorbent assay (ELISA)...
January 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29339849/can-an-exostosis-be-free-floating-without-any-continuity-to-the-underlying-bone-a-diagnostic-dilemma
#5
Manish Kanwat, Vivek Jangira, Bhavna Sharma, Dushyant Chauhan
Osteochondroma or exostosis is the most common primary bone tumor containing both bone and cartilage. Soft tissue osteochondromas have been described at various locations, however, to the best of our knowledge, there is only a single case report of a soft tissue osteochondroma around the femoral neck. We, hereby report second such case. CASE REPORT: A forty year old female presented with swelling on medial aspect of left thigh since four years. Radiographs showed a large mass at the inferior surface of the left femoral neck...
November 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29333031/a-case-of-multifocal-eosinophilic-granuloma-involving-spine-and-pelvis-in-a-young-adult-a-radiopathological-correlation
#6
Santosh Rai, H B Sridevi, Radha R Pai, Pulastya Sanyal
We present a case of multiple osteolytic lesions in a 28-year-old adult who presented with headache, back pain, and hip pain of 6 months. There was no history of localized swelling or rise of temperature, no history of weight loss or evening rise of temperature. On examination, there were no focal neurological deficits. Routine laboratory investigations, including total leukocyte counts, differential leukocyte counts, hemoglobin, and platelet counts, were within normal limits. There was a borderline elevation of erythrocyte sedimentation rate...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29331010/implants-for-extracapsular-neck-of-femur-fracture-dynamic-hip-screw-versus-intramedullary-nailing
#7
Faisal Farooq Butt, Adnan Shabbair Hussain, Ahmed Mushtaq Khan, Maria Sultan
Neck of femur fractures are the most prevalent type of injury in elderly trauma patients. Both intra and extra capsular type of fractures are equally distributed in the given population. Traditionally, Extra capsular fractures are fixed with Dynamic Hip screw or Intra medullary nailing based on the type of fracture. NICE (National Institute of Clinical Excellence) recommends fixing 31-A1 and 31-A2 fractures with DHS (Dynamic Hip Screw) whereas AO recommends fixing 31-A1 with DHS and 31-A2.1 subtype with DHS and 31-A2...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29328790/hospital-stay-and-blood-transfusion-in-elderly-patients-with-hip-fractures
#8
Efthymios Iliopoulos, Sohail Yousaf, Hazel Watters, Arshad Khaleel
Neck of femur (NOF) fractures in elderly patients are the most frequent condition which an orthopaedic surgeon confronts nowadays. The incidence of these fractures is increasing as the population continues to age. These patients absorb the majority of the resources in the hospitals, as their healthcare demands are increased. This study included all patients who were admitted to our hospital between January and October 2015 following a neck of femur fracture. A total of 336 patients were included (72.3% female)...
December 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29327108/computed-tomography-for-occult-fractures-of-the-proximal-femur-pelvis-and-sacrum-in-clinical-practice-single-institution-dual-site-experience
#9
Jacob C Mandell, Michael J Weaver, Bharti Khurana
PURPOSE: The purpose of this study was to evaluate the diagnostic performance of CT for assessment of occult fractures of the proximal femur, pelvis, and sacrum. MATERIALS AND METHODS: A retrospective review was performed on patients who received a CT of the hip or pelvis for suspected occult fracture after negative or equivocal radiographs performed within 24 h. The official radiology report was utilized for the determination of CT findings and calculation of sensitivity and specificity...
January 11, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29322292/bilateral-symmetrical-comparison-of-the-proximal-femur-using-3d-ct-models
#10
Filip C Dolatowski, Max J Temmesfeld, Claude Pierre-Jerome, Arne Borthne, Sigurd Erik Hoelsbrekken
PURPOSE: Superimposed three-dimensional (3D)-models obtained from CT-images have been used to evaluate displacement of femoral neck fractures, but this method assumes symmetrical anatomy of normal femurs. The present study aimed to compare the spatial orientation of the left and right proximal femur, thus establishing if 3D models can be used as a reference standard for the evaluation of fracture displacement. METHODS: We generated 3D-CT-models of 20 patients with no skeletal pathology of the proximal femurs...
January 10, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29321359/association-of-lactase-13910-c-t-polymorphism-with-bone-mineral-density-and-fracture-risk-a-meta-analysis
#11
Yougen Wu, Yinghua Li, Yunqing Cui, Yunjiao Zhou, Qingqing Qian, Yang Hong
A number of studies have investigated the association of lactase (LCT,C/T-13910) gene polymorphismwith bonemineral density (BMD) and fracture risk, but previous results were inconclusive. In this study, a meta-analysis was performed to quantify the association of LCT (C/T-13910) polymorphism with BMD and fracture risk. Eligible publications were searched in the PubMed, Web of Science, Embase databases, Google Scholar, Yahoo and Baidu. Pooled weighed mean difference (WMD) or odds ratio (OR) with their 95% confidence interval (CI) were calculated using a fixed-effects or random-effects model...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29320924/a-model-to-evaluate-pauwels-type-iii-femoral-neck-fractures
#12
Kevin M Magone, Jonas K Owen, Bernard P Kemker, Oliver Bloom, Sidney Martin, Patrick Atkinson
While many femoral neck fractures can be reliably treated with surgical intervention, Pauwels III femoral neck fractures in the young adult population continue to be a challenging injury, and there is no consensus on optimal treatment. As such, there are past and ongoing biomechanical studies to evaluate the fixation provided by different constructs for this inherently unstable fracture. While many investigations rely on cadavers to evaluate the biomechanical performance of a construct, significant inter-subject variability can confound the analysis...
January 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29318081/-hidden-preoperative-blood-loss-with-extracapsular-versus-intracapsular-hip-fractures-what-is-the-difference
#13
Katharine D Harper, Paul Navo, Frederick Ramsey, Sainabou Jallow, Saqib Rehman
Purpose: Excessive blood loss with hip fracture management has been shown to result in increased rates of complications. Our goal is to compare blood loss and transfusion rates between patients with intracapsular and extracapsular (both intertrochanteric (IT) and subtrochanteric (ST)) hip fractures. Methods: 472 patients were evaluated over a five-year period. Those who presented to the hospital with a proximal femur fracture (femoral neck, IT or ST) were considered for the study...
December 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29318009/assessment-of-osteoporosis-using-the-frax-method-and-the-importance-of-vitamin-d-levels-in-copd-patients
#14
Ceyda Anar, Melike Yüksel Yavuz, Filiz Güldaval, Yelda Varol, Dilek Kalenci
Background: The aim of this paper was to evaluate the availability of FRAX for assessing osteoporosis risk, and to demonstrate the importance of vitamin D levels in COPD patients. Methods: Fourty-six males who fulfilled the COPD diagnostic criteria defined by GOLD were included. Age, race, BMI, physical activity frequency, smoking and dietary habits, age at COPD diagnosis, disease duration, fractures history, and medications use were determined. Levels of 25(OH)D were detected...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29317966/epithelioid-angiosarcoma-in-femur-a-case-presentation
#15
Yunus Oc, Bekir Eray Kilinc, Rodi Ertugrul, Hasan Basri Sezer, Osman Tugrul Eren
Primary malignant vascular tumors which constitute less than 1% of the primary bone tumors are very rarely encountered. Epithelioid angiosarcoma is a very uncommon subtype of angiosarcomas presenting with an epithelioid phenotype and mimicking carcinomas clinically. These tumors select mostly extra-skeletal locations but rarely bones as their medium. A 31-year-old male patient applied to our clinic with a nonspecific left hip pain. X-ray evaluation revealed a cystic expansile mass in the trochanteric region of the femur extending to the femoral neck...
December 2017: World Journal of Oncology
https://www.readbyqxmd.com/read/29315035/does-a-daily-consultant-ward-round-affect-the-outcomes-of-orthopaedic-patients
#16
Kwaku W Baryeh, David Elliott, Ziad Harb, Radcliffe Lisk
INTRODUCTION: In the UK, more than 60 000 patients present with a fractured neck of femur each year. These patients represent a huge financial cost. This study looks at the 30-day readmissions and total length of hospital stay of patients presenting with a fractured neck of femur, as well as length of stay in non-hip fracture trauma patients, following the change to a daily consultant-led ward round. METHODS: A total of 200 records of patients with fractured neck of femur were reviewed with data collected retrospectively and prospectively following the introduction of the daily consultant-led ward round...
January 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29314652/evaluation-of-bone-stimulation-by-different-designs-of-microthreaded-implants-in-enhancing-osseointegration-an-in-vivo-animal-study-supported-by-a-numerical-analysis
#17
Sindhu Sudhakar Kumararama, Sunil Mishra, Ramesh Chowdhary
BACKGROUND: An optimal shape of the thread design of the implants is required for equal distribution of stresses to the surrounding bone matrix and for stimulation and promotion of bone remodeling. PURPOSE: The study was construed with the aim of histomorphometric evaluation of bone stimulation generated by different microthread designed implants in enhancing osseointegration, and to assess the pattern of stress dissipation through a two-dimensional finite element analysis...
January 4, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29298262/body-mass-index-affects-proximal-femoral-but-not-acetabular-morphology-in-adolescents-without-hip-pathology
#18
Eduardo N Novais, Sandra J Shefelbine, Karl-Philipp Kienle, Patricia E Miller, Garrett Bowen, Young-Jo Kim, Sarah D Bixby
BACKGROUND: Increased mechanical load secondary to a large body mass index (BMI) may influence bone remodeling. The purpose of this study was to investigate whether BMI is associated with the morphology of the proximal part of the femur and the acetabulum in a cohort of adolescents without a history of hip disorders. METHODS: We evaluated pelvic computed tomographic (CT) images in 128 adolescents with abdominal pain without a history of hip pathology. There were 44 male patients (34%) and the mean patient age (and standard deviation) was 15 ± 1...
January 3, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29289395/modified-false-profile-radiograph-of-the-hip-provides-better-visualization-of-the-anterosuperior-femoral-head-neck-junction
#19
Penny R Atkins, Evangeline F Kobayashi, Andrew E Anderson, Stephen K Aoki
PURPOSE: The purpose of this study was to quantify the amount of internal femur rotation required to visualize the 12 to 3 o'clock positions of the femoral head-neck junction as seen on the false-profile radiograph. METHODS: Computed tomography (CT) images of the femur were retrospectively reviewed from control subjects and cam femoroacetabular impingement (FAI) patients. Using an automatically determined clockface, the positions between 12 and 3 o'clock were determined...
December 27, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29276731/the-role-of-the-p2x7-receptor-on-bone-loss-in-a-mouse-model-of-inflammation-mediated-osteoporosis
#20
T M Kvist, S Syberg, S Petersen, M Ding, N R Jørgensen, P Schwarz
In inflammatory autoimmune diseases, bone loss is frequent. In most cases, secondary osteoporosis is caused by treatment with systemic glucocorticoid. However, the pathogenesis behind the bone loss is presumed multifactorial. We aimed to elucidate the role of the P2X7 receptor on bone mineral density (BMD), microarchitecture, and bone strength in a standardized mouse model of inflammation-mediated osteoporosis (IMO). In total 146 mice completed our protocol, 70 wild type (WT) mice and 76 P2X7 -/- (knockout, KO)...
December 2017: Bone Reports
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