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JOURNAL ARTICLE
Omar Dueñas-Garcia, Robinson Lindsey, Marshall Elly, Lemon Kelly, Breyel Janine, Umer Amna, Hercules Catherine, Lilly Christa
The main objective of this study was to analyze perinatal outcomes of women with substance use disorder in pregnancy who participated in the West Virginia University Medicine Drug Free Moms and Babies Assist Connect and Encourage program (DFMB/ACE) compared to women who were not enrolled in the program. This was a retrospective cohort study conducted in an l Academic Tertiary Care Center. Women who enrolled in DFMB/ACE services from 2018 to 2019 were termed as the intervention group. Their outcomes were compared to 734 women who delivered at the hospital between July 2015 and December 2019 with a positive urine drug screen on admission but were not enrolled in the DFMB/ACE program...
October 2023: Preventive Medicine Reports
#2
JOURNAL ARTICLE
Sogol Koolaji, Yeganeh Sharifnejad Tehrani, Sina Azadnajafabad, Sahar Saeedi Moghaddam, Sarvenaz Shahin, Azin Ghamari, Naser Ahmadi, Negar Rezaei, Mohammad Keykhaei, Hamed Tavolinejad, Seyyed-Hadi Ghamari, Mohsen Abbasi-Kangevari, Nazila Rezaei, Bagher Larijani, Farshad Farzadfar
BACKGROUND: Evaluating the burden of ischemic heart disease (IHD) as the first cause of mortality worldwide is necessary to develop healthcare policies. This study aimed to report the national and subnational IHD burden and risk factors in Iran according to the Global Burden of Disease (GBD) study 2019. METHODS: We extracted, processed, and presented the results of the GBD 2019 study regarding incidence, prevalence, deaths, years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life years (DALYs), and attributable burden to risk factors of IHD in Iran during 1990-2019...
May 15, 2023: International Journal of Cardiology
#3
JOURNAL ARTICLE
Quan Huynh, Alison J Venn, Costan G Magnussen, Hong Yang, Prasanna Venkataraman, Terence Dwyer, Thomas H Marwick
We sought to apply a simple cardiovascular health tool not requiring laboratory tests (the Fuster-BEWAT score, FBS) to predict subclinical atherosclerosis. This study included 2657 young adults (< 40 years of age). In the prognostic group (n = 894, followed for 13 years until aged 40-50 years at follow-up), the primary outcome was presence of carotid plaque measured by carotid ultrasound at follow-up. Of these 894 participants, 86 (9.6%) had unilateral, and 23 participants (2...
February 3, 2023: BMC Cardiovascular Disorders
#4
JOURNAL ARTICLE
Dahu Chen, Kamrun Nahar
A survey on field pea (Pisum sativum) root rot was carried out in Prince Edward Island (PEI) and New Brunswick (NB), Canada, between July and August, 2018. The average disease incidence was 75% and 78%, and severity was 3.5 and 2.8 on a 1 to 7 scale for NB and PEI, respectively (Schneider and Kelly 2000). Symptoms included seedling stunting, root rot, and wilting. Surface sterilized diseased root segments were incubated on water agar at 25°C for 5 days. Pure isolates were obtained by single spore culturing...
January 10, 2023: Plant Disease
#5
JOURNAL ARTICLE
Meghan M Hewlett, Maria C Raven, Dave Graham-Squire, Jennifer L Evans, Caroline Cawley, Margot Kushel, Hemal K Kanzaria
BACKGROUND: In the City and County of San Francisco, frequent users of emergent and urgent services across different settings (i.e., medical, mental health (MH), substance use disorder (SUD) services) are referred to as high users of multiple systems (HUMS). While often grouped together, frequent users of the health care system are likely a heterogenous population composed of subgroups with differential management needs. OBJECTIVE: To identify subgroups within this HUMS population using a cluster analysis...
November 29, 2022: Journal of General Internal Medicine
#6
JOURNAL ARTICLE
Aleksandra Frątczak, Karina Polak, Bartosz Miziołek, Beata Bergler-Czop
Torasemide is a loop diuretic with a molecule that is chemically similar to the sulphonamides described as eosinophilic granulomatosis with polyangiitis (EGPA) triggering drugs. The presented case is probably the first description of torasemide-induced vascular purpura in the course of EGPA. Any diagnosis of vasculitis should be followed by an identification of drugs that may aggravate the disease. A 74-year-old patient was admitted to the Department of Dermatology with purpura-like skin lesions on the upper, and lower extremities, including the buttocks...
September 2022: Acta Dermatovenerologica Croatica: ADC
#7
JOURNAL ARTICLE
Masaki Shoji, Naoki Sakane, Naoki Ito, Keiji Sunayama, Mitsuko Onda
Background: In Japan, there is a pressing need to improve community health care to cope with the rapid aging of the population. In this context, there have been private-sector-led approaches to enhance community dietary support by employing dietitians in pharmacies. Objectives: To evaluate the effects of collaboration between dietitians and pharmacists working in pharmacies to support patients with type 2 diabetes. Methods: A single group pre- and post-comparative study was conducted on patients with type 2 diabetes mellitus...
April 2022: Pharmacy Practice
#8
REVIEW
Ximena Calle, Valeria Garrido-Moreno, Erik Lopez-Gallardo, Ignacio Norambuena-Soto, Daniela Martínez, Allan Peñaloza-Otárola, Angelo Troncossi, Alejandra Guerrero-Moncayo, Angélica Ortega, Vinicius Maracaja-Coutinho, Valentina Parra, Mario Chiong, Sergio Lavandero
Mitochondrial E3 ubiquitin ligase 1 (MUL1) is a mitochondrial outer membrane-anchored protein-containing transmembrane domain in its N- and C-terminal regions, where both are exposed to the cytosol. Interestingly the C-terminal region has a RING finger domain responsible for its E3 ligase activity, as ubiquitin or in SUMOylation, interacting with proteins related to mitochondrial fusion and fission, cell survival, and tumor suppressor process, such as Akt. Therefore, MUL1 is involved in various cellular processes, such as mitochondrial dynamics, inter-organelle communication, proliferation, mitophagy, immune response, inflammation and cell apoptosis...
September 2022: IUBMB Life
#9
JOURNAL ARTICLE
Nicholas Kassis, Essa H Hariri, Antonette K Karrthik, Keerat R Ahuja, Habib Layoun, Anas M Saad, Mohamed M Gad, Manpreet Kaur, Najdat Bazarbashi, Brian P Griffin, Zoran B Popovic, Serge C Harb, Milind Y Desai, Samir R Kapadia
OBJECTIVE: Calcium metabolism has long been implicated in aortic stenosis (AS). Studies assessing the long-term safety of oral calcium and/or vitamin D in AS are scarce yet imperative given the rising use among an elderly population prone to deficiency. We sought to identify the associations between supplemental calcium and vitamin D with mortality and progression of AS. METHODS: In this retrospective longitudinal study, patients aged ≥60 years with mild-moderate native AS were selected from the Cleveland Clinic Echocardiography Database from 2008 to 2016 and followed until 2018...
May 25, 2022: Heart
#10
JOURNAL ARTICLE
Lívia F G Chaves, Mayra M M Ferro, Mayara O de Lima, Iraildes P Assunção, Gaus S A Lima, Sarah J C da Silva
A novel bipartite begomovirus infecting Cnidoscolus urens (Euphorbiaceae) from Pernambuco State, Brazil, has been characterized. The complete DNA-A (2657 nt) and DNA-B (2622 nt) components of the viral isolates show the typical genome organization of New World bipartite begomoviruses. DNA-A of the isolates had the highest percentage of nucleotide sequence identity (88.6-88.9%) to cnidoscolus mosaic leaf deformation virus. Based on the current classification criteria for the genus Begomovirus, the virus infecting C...
February 11, 2022: Archives of Virology
#11
JOURNAL ARTICLE
Fernanda Dos Anjos, Jonatha Wruck, Thiago Inácio Teixeira do Carmo, Victor Emanuel Miranda Soares, Débora Tavares de Resende E Silva, Margarete Dulce Bagatini, Sarah Franco Vieira de Oliveira Maciel
Cystic Fibrosis is a monogenic and autosomal recessive disease. It is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator gene responsible for encoding the CFTR protein. Involvement of the gastrointestinal and respiratory systems is the main clinical manifestation. In this case, we report a heterozygous CFTR patient harboring class I (p.Gly542*) and class V (c.2657+5G>A) mutations. The importance of this case report lies in the clinical features because the patient, aged three years old, presents early exocrine pancreatic insufficiency, which can be considered atypical, as most individuals with this genotype are pancreatic sufficient or develop pancreatic insufficiency later in life...
February 7, 2022: Clinical Medicine & Research
#12
JOURNAL ARTICLE
Nimmi Rajmohan, Dana Price, Richard Buckley, Stephen J Komar, William J Bamka, Eric A Petit, Raul I Cabrera, Tom Gianfagna, James E Simon, Christian A Wyenandt
In December 2019, New Jersey became one of the first states to have its Industrial Hemp (Cannabis sativa L.) plan approved by the U.S. Department of Agriculture (USDA) following enactment of the 2018 Farm Bill that authorized the production of hemp. Following this approval hemp was legally grown for the first time in 2020. During the growing seasons of 2020 and 2021, powdery mildew-like symptoms were observed in field and greenhouse hemp research plots on Rutgers agricultural experiment station farms in southern and northern New Jersey...
February 7, 2022: Plant Disease
#13
JOURNAL ARTICLE
Alexandria Smith, Stephen Breazeale, Joseph L Goulet, David Vlahov, Amy C Justice, Julie A Womack
Persons living with HIV (PWH) are at elevated risk for suicide. We conducted a systematic literature review following PRISMA-P guidelines to examine risk factors associated with suicide as a cause of morbidity among PWH. We searched six electronic databases using search terms (suicide, suicide attempt, self-harm, self-injurious behavior, HIV, AIDS, PWH). We focused on factors that were specific to HIV infection (CD4 count, HIV-1 RNA, and antiretroviral therapy [ART]). The initial search yielded N = 2657 studies...
February 2, 2022: AIDS and Behavior
#14
REVIEW
Ricardo Tukiama, René A C Vieira, Ed C R Moura, Ana G C Oliveira, Gil Facina, Gustavo Zucca-Matthes, João N Neto, Caio M B de Oliveira, Plínio da Cunha Leal
BACKGROUND: Autologous fat grating has become increasingly popular as a breast reconstructive procedure. Nevertheless, preclinical studies show that fat transfer to a previous breast cancer site could activate latent cancer cells, creating a favourable environment for disease recurrence. A systematic review and meta-analysis was performed to investigate whether fat grafting increases the risk of locoregional recurrence in patients formerly treated for breast cancer. METHODS: Based on PRISMA guidelines, a systematic review searching for randomised clinical trials and matched cohorts on the topic was performed in the electronic databases Pubmed, Embase, Web of Science, and Cochrane...
December 22, 2021: European Journal of Surgical Oncology
#15
JOURNAL ARTICLE
Chloe Kern, Joy Wan, Kaja Z LeWinn, Faustine D Ramirez, Yong Lee, Charles E McCulloch, Sinéad M Langan, Katrina Abuabara
IMPORTANCE: Research has highlighted associations between atopic dermatitis (AD) and mental health conditions in adults. However, literature on the development of mental health comorbidities in children is limited despite the large burden of pediatric AD worldwide. OBJECTIVE: To examine the association between AD and internalizing behaviors and symptoms of depression at multiple points across childhood and adolescence and to explore potential mediating factors, including asthma/rhinitis, sleep, and inflammation...
October 1, 2021: JAMA Dermatology
#16
MULTICENTER STUDY
Zachi I Attia, Suraj Kapa, Jennifer Dugan, Naveen Pereira, Peter A Noseworthy, Francisco Lopez Jimenez, Jessica Cruz, Rickey E Carter, Daniel C DeSimone, John Signorino, John Halamka, Nikhita R Chennaiah Gari, Raja Sekhar Madathala, Pyotr G Platonov, Fahad Gul, Stefan P Janssens, Sanjiv Narayan, Gaurav A Upadhyay, Francis J Alenghat, Marc K Lahiri, Karl Dujardin, Melody Hermel, Paari Dominic, Karam Turk-Adawi, Nidal Asaad, Anneli Svensson, Francisco Fernandez-Aviles, Darryl D Esakof, Jozef Bartunek, Amit Noheria, Arun R Sridhar, Gaetano A Lanza, Kevin Cohoon, Deepak Padmanabhan, Jose Alberto Pardo Gutierrez, Gianfranco Sinagra, Marco Merlo, Domenico Zagari, Brenda D Rodriguez Escenaro, Dev B Pahlajani, Goran Loncar, Vladan Vukomanovic, Henrik K Jensen, Michael E Farkouh, Thomas F Luescher, Carolyn Lam Su Ping, Nicholas S Peters, Paul A Friedman
OBJECTIVE: To rapidly exclude severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using artificial intelligence applied to the electrocardiogram (ECG). METHODS: A global, volunteer consortium from 4 continents identified patients with ECGs obtained around the time of polymerase chain reaction-confirmed COVID-19 diagnosis and age- and sex-matched controls from the same sites. Clinical characteristics, polymerase chain reaction results, and raw electrocardiographic data were collected...
August 2021: Mayo Clinic Proceedings
#17
Hui-Fang Liu, Qing Li, You-Qun Peng
BACKGROUND: Alport syndrome (ATS) is a rare hereditary disease caused by mutations in genes such as COL4A3, COL4A4, and COL4A5 . ATS involves a spectrum of phenotypes ranging from isolated hematuria that is nonprogressive to progressive renal disease with extrarenal abnormalities. Although ATS can be combined with other diseases or syndromes, ATS combined with lupus nephritis has not been reported before. CASE SUMMARY: A Chinese family with ATS was recruited for the current study...
June 26, 2021: World Journal of Clinical Cases
#18
JOURNAL ARTICLE
S M Naim Uddin, Farhana Sultana, Md Giash Uddin, Syed Masudur Rahman Dewan, Mohammed Kamrul Hossain, Mohammad Safiqul Islam
BACKGROUND: Schizophrenia (SCZ) is an incurable neuropsychiatric disorder generally described by impaired social behavior and altered recognition of reality. For the first time, this study explored serum levels of antioxidants (vitamin A, E, and C), malondialdehyde (MDA), macro-minerals (calcium, potassium, and sodium), and trace elements (zinc, iron, and selenium) in Bangladeshi patients with SCZ and thereby, discovering any pathophysiological correlation. METHODS: This case-controlled study evaluated 63 patients with SCZ as cases and 63 healthy individuals as controls...
June 2021: Health Science Reports
#19
JOURNAL ARTICLE
Xiaoting Sun, Xinxin Zhao, Han Zhang, Jue Li, Chenghua Jiang, Yihan Chen, Jialin C Zheng
No abstract text is available yet for this article.
March 2021: Annals of Family Medicine
#20
JOURNAL ARTICLE
Joseph E Blais, Gloria Kin Yi Tong, Swathi Pathadka, Michael Mok, Ian C K Wong, Esther W Chan
OBJECTIVE: To assess whether in adults with dyslipidemia, statins reduce cardiovascular events, mortality, and adverse effects when compared to fibrates. METHODS: Systematic review and meta-analysis of head-to-head randomized trials of statin and fibrate monotherapy. MEDLINE, EMBASE, Cochrane, WHO International Controlled Trials Registry Platform, and ClinicalTrials.gov were searched through October 30, 2019. Trials that had a follow-up of at least 28 days, and reported mortality or a cardiovascular outcome of interest were eligible for inclusion...
2021: PloS One
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