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Catherine Goodman

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https://www.readbyqxmd.com/read/29318656/circadian-genes-and-risk-of-prostate-cancer-in-the-prostate-cancer-prevention-trial
#1
Lisa W Chu, Cathee Till, Baiyu Yang, Catherine M Tangen, Phyllis J Goodman, Kai Yu, Yong Zhu, Summer Han, Ashraful M Hoque, Christine Ambrosone, Ian Thompson, Robin Leach, Ann W Hsing
Circadian genes have been considered as a possible biological mechanism for the observed relationship between circadian rhythm disruptions and increased risk of hormone-related cancers. In the current study, we investigated the relationship between circadian gene variants and prostate cancer risk and whether reducing bioavailable testosterone modifies the circadian genes-prostate cancer relationship. We conducted a nested case-control study among Caucasian men in the Prostate Cancer Prevention Trial (PCPT), a randomized placebo-controlled clinical trial to assess if finasteride (an androgen bioactivation inhibitor) could prevent prostate cancer...
January 10, 2018: Molecular Carcinogenesis
https://www.readbyqxmd.com/read/29281666/circulating-sex-hormones-in-relation-to-anthropometric-sociodemographic-and-behavioural-factors-in-an-international-dataset-of-12-300-men
#2
Eleanor L Watts, Paul N Appleby, Demetrius Albanes, Amanda Black, June M Chan, Chu Chen, Piera M Cirillo, Barbara A Cohn, Michael B Cook, Jenny L Donovan, Luigi Ferrucci, Cedric F Garland, Graham G Giles, Phyllis J Goodman, Laurel A Habel, Christopher A Haiman, Jeff M P Holly, Robert N Hoover, Rudolf Kaaks, Paul Knekt, Laurence N Kolonel, Tatsuhiko Kubo, Loïc Le Marchand, Tapio Luostarinen, Robert J MacInnis, Hanna O Mäenpää, Satu Männistö, E Jeffrey Metter, Roger L Milne, Abraham M Y Nomura, Steven E Oliver, J Kellogg Parsons, Petra H Peeters, Elizabeth A Platz, Elio Riboli, Fulvio Ricceri, Sabina Rinaldi, Harri Rissanen, Norie Sawada, Catherine A Schaefer, Jeannette M Schenk, Frank Z Stanczyk, Meir Stampfer, Pär Stattin, Ulf-Håkan Stenman, Anne Tjønneland, Antonia Trichopoulou, Ian M Thompson, Shoichiro Tsugane, Lars Vatten, Alice S Whittemore, Regina G Ziegler, Naomi E Allen, Timothy J Key, Ruth C Travis
INTRODUCTION: Sex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the associations of anthropometric, sociodemographic and behavioural factors with a range of circulating sex hormones and sex hormone-binding globulin. METHODS: Statistical analyses of individual participant data from 12,330 male controls aged 25-85 years from 25 studies involved in the Endogenous Hormones Nutritional Biomarkers and Prostate Cancer Collaborative Group...
2017: PloS One
https://www.readbyqxmd.com/read/29275135/effect-of-a-multifaceted-social-franchising-model-on-quality-and-coverage-of-maternal-newborn-and-reproductive-health-care-services-in-uttar-pradesh-india-a-quasi-experimental-study
#3
Sarah Tougher, Varun Dutt, Shreya Pereira, Kaveri Haldar, Vasudha Shukla, Kultar Singh, Paresh Kumar, Catherine Goodman, Timothy Powell-Jackson
BACKGROUND: How to harness the private sector to improve population health in low-income and middle-income countries is heavily debated and one prominent strategy is social franchising. We aimed to evaluate whether the Matrika social franchising model-a multifaceted intervention that established a network of private providers and strengthened the skills of both public and private sector clinicians-could improve the quality and coverage of health services along the continuum of care for maternal, newborn, and reproductive health...
December 20, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29238824/effect-of-perioperative-gabapentin-on-postoperative-pain-resolution-and-opioid-cessation-in-a-mixed-surgical-cohort-a-randomized-clinical-trial
#4
Jennifer Hah, Sean C Mackey, Peter Schmidt, Rebecca McCue, Keith Humphreys, Jodie Trafton, Bradley Efron, Debra Clay, Yasamin Sharifzadeh, Gabriela Ruchelli, Stuart Goodman, James Huddleston, William J Maloney, Frederick M Dirbas, Joseph Shrager, John Costouros, Catherine Curtin, Ian Carroll
Importance: Guidelines recommend using gabapentin to decrease postoperative pain and opioid use, but significant variation exists in clinical practice. Objective: To determine the effect of perioperative gabapentin on remote postoperative time to pain resolution and opioid cessation. Design, Setting, and Participants: A randomized, double-blind, placebo-controlled trial of perioperative gabapentin was conducted at a single-center, tertiary referral teaching hospital...
December 13, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29228205/associations-between-polymorphisms-in-genes-related-to-estrogen-metabolism-and-function-and-prostate-cancer-risk-results-from-the-prostate-cancer-prevention-trial
#5
Li Tang, Mary E Platek, Song Yao, Cathee Till, Phyllis J Goodman, Catherine M Tangen, Yue Wu, Elizabeth A Platz, Marian L Neuhouser, Frank Z Stanczyk, Juergen K V Reichardt, Regina M Santella, Ann Hsing, William D Figg, Scott M Lippman, Ian M Thompson, Christine B Ambrosone
Substantial preclinical data suggest estrogen's carcinogenic role in prostate cancer development; however, epidemiological evidence based on circulating estrogen levels is largely null. Compared with circulating estrogen, the intraprostatic estrogen milieu may play a more important role in prostate carcinogenesis. Using a nested case-control design in the Prostate Cancer Prevention Trial (PCPT), we examined associations of genetic variants of genes that are involved in estrogen synthesis, metabolism and function with prostate cancer risk...
December 8, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29181453/supporting-surveillance-capacity-for-antimicrobial-resistance-laboratory-capacity-strengthening-for-drug-resistant-infections-in-low-and-middle-income-countries
#6
Anna C Seale, Coll Hutchison, Silke Fernandes, Nicole Stoesser, Helen Kelly, Brett Lowe, Paul Turner, Kara Hanson, Clare I R Chandler, Catherine Goodman, Richard A Stabler, J Anthony G Scott
Development of antimicrobial resistance (AMR) threatens our ability to treat common and life threatening infections. Identifying the emergence of AMR requires strengthening of surveillance for AMR, particularly in low and middle-income countries (LMICs) where the burden of infection is highest and health systems are least able to respond. This work aimed, through a combination of desk-based investigation, discussion with colleagues worldwide, and visits to three contrasting countries (Ethiopia, Malawi and Vietnam), to map and compare existing models and surveillance systems for AMR, to examine what worked and what did not work...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29141849/polycystic-ovary-syndrome-oligomenorrhea-and-risk-of-ovarian-cancer-histotypes-evidence-from-the-ovarian-cancer-association-consortium
#7
Holly R Harris, Ana Babic, Penelope M Webb, Christina M Nagle, Susan J Jordan, Harvey A Risch, Mary Anne Rossing, Jennifer A Doherty, Marc T Goodman, Francesmary Modugno, Roberta B Ness, Kirsten B Moysich, Susanne K Kjaer, Estrid Høgdall, Allan Jensen, Joellen M Schildkraut, Andrew Berchuck, Daniel W Cramer, Elisa V Bandera, Nicolas Wentzensen, Joanne Kotsopoulos, Steven A Narod, Catherine M Phelan, John R McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Celeste Leigh Pearce, Anna H Wu, Kathryn L Terry
BACKGROUND: Polycystic ovary syndrome (PCOS), and one if its distinguishing characteristics, oligomenorrhea, have both been associated with ovarian cancer risk in some but not all studies. However, these associations have been rarely been examined by ovarian cancer histotypes which may explain the lack of clear associations reported in previous studies. METHODS: We analyzed data from 14 case-control studies including 16,594 women with invasive ovarian cancer (n=13,719) or borderline ovarian disease (n=2,875) and 17,718 controls...
November 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29134193/snowball-earth-climate-dynamics-and-cryogenian-geology-geobiology
#8
Paul F Hoffman, Dorian S Abbot, Yosef Ashkenazy, Douglas I Benn, Jochen J Brocks, Phoebe A Cohen, Grant M Cox, Jessica R Creveling, Yannick Donnadieu, Douglas H Erwin, Ian J Fairchild, David Ferreira, Jason C Goodman, Galen P Halverson, Malte F Jansen, Guillaume Le Hir, Gordon D Love, Francis A Macdonald, Adam C Maloof, Camille A Partin, Gilles Ramstein, Brian E J Rose, Catherine V Rose, Peter M Sadler, Eli Tziperman, Aiko Voigt, Stephen G Warren
Geological evidence indicates that grounded ice sheets reached sea level at all latitudes during two long-lived Cryogenian (58 and ≥5 My) glaciations. Combined uranium-lead and rhenium-osmium dating suggests that the older (Sturtian) glacial onset and both terminations were globally synchronous. Geochemical data imply that CO2 was 10(2) PAL (present atmospheric level) at the younger termination, consistent with a global ice cover. Sturtian glaciation followed breakup of a tropical supercontinent, and its onset coincided with the equatorial emplacement of a large igneous province...
November 2017: Science Advances
https://www.readbyqxmd.com/read/29100550/effects-of-a-liquefied-petroleum-gas-stove-intervention-on-pollutant-exposure-and-adult-cardiopulmonary-outcomes-chap-study-protocol-for-a-randomized-controlled-trial
#9
Magdalena Fandiño-Del-Rio, Dina Goodman, Josiah L Kephart, Catherine H Miele, Kendra N Williams, Mitra Moazzami, Elizabeth C Fung, Kirsten Koehler, Victor G Davila-Roman, Kathryn A Lee, Saachi Nangia, Steven A Harvey, Kyle Steenland, Gustavo F Gonzales, William Checkley
BACKGROUND: Biomass fuel smoke is a leading risk factor for the burden of disease worldwide. International campaigns are promoting the widespread adoption of liquefied petroleum gas (LPG) in resource-limited settings. However, it is unclear if the introduction and use of LPG stoves, in settings where biomass fuels are used daily, reduces pollution concentration exposure, improves health outcomes, or how cultural and social barriers influence the exclusive adoption of LPG stoves. METHODS: We will conduct a randomized controlled, field intervention trial of LPG stoves and fuel distribution in rural Puno, Peru, in which we will enroll 180 female participants aged 25-64 years and follow them for 2 years...
November 3, 2017: Trials
https://www.readbyqxmd.com/read/29053944/investigation-of-the-3-epi-25-oh-d3-of-25-hydroxyvitamin-d3-in-urban-schoolchildren
#10
Samantha E Berger, Maria I Van Rompay, Catherine M Gordon, Elizabeth Goodman, Misha Eliasziw, Michael F Holick, Jennifer M Sacheck
BACKGROUND: The physiological relevance C-3 epimer of 25-hydroxyvitamin D [3-epi-25(OH)D] is not well understood among youth. OBJECTIVE: To assess whether demographic/physiologic characteristics were associated with 3-epi-25(OH)D3 concentrations in youth. METHODS: Associations between 3-epi-25(OH)D3 and demographics, 3-epi-25(OH)D3, total 25-hydroxyvitamin (25(OH)D) (25(OH)D2 + 25(OH)D3), total cholesterol, HDL, LDL and triglycerides were examined in racially/ethnically diverse schoolchildren (n=682, 8-15yrs) at Boston-area urban schools...
October 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29049607/dose-response-association-of-cd8-tumor-infiltrating-lymphocytes-and-survival-time-in-high-grade-serous-ovarian-cancer
#11
Ellen L Goode, Matthew S Block, Kimberly R Kalli, Robert A Vierkant, Wenqian Chen, Zachary C Fogarty, Aleksandra Gentry-Maharaj, Aleksandra Toloczko, Alexander Hein, Aliecia L Bouligny, Allan Jensen, Ana Osorio, Andreas D Hartkopf, Andy Ryan, Anita Chudecka-Glaz, Anthony M Magliocco, Arndt Hartmann, Audrey Y Jung, Bo Gao, Brenda Y Hernandez, Brooke L Fridley, Bryan M McCauley, Catherine J Kennedy, Chen Wang, Chloe Karpinskyj, Christiani B de Sousa, Daniel G Tiezzi, David L Wachter, Esther Herpel, Florin Andrei Taran, Francesmary Modugno, Gregg Nelson, Jan Lubinski, Janusz Menkiszak, Jennifer Alsop, Jenny Lester, Jesús García-Donas, Jill Nation, Jillian Hung, José Palacios, Joseph H Rothstein, Joseph L Kelley, Jurandyr M de Andrade, Luis Robles-Díaz, Maria P Intermaggio, Martin Widschwendter, Matthias W Beckmann, Matthias Ruebner, Mercedes Jimenez-Linan, Naveena Singh, Oleg Oszurek, Paul R Harnett, Peter F Rambau, Peter Sinn, Philipp Wagner, Prafull Ghatage, Raghwa Sharma, Robert P Edwards, Roberta B Ness, Sandra Orsulic, Sara Y Brucker, Sharon E Johnatty, Teri A Longacre, Ursula Eilber, Valerie McGuire, Weiva Sieh, Yanina Natanzon, Zheng Li, Alice S Whittemore, Anna deFazio, Annette Staebler, Beth Y Karlan, Blake Gilks, David D Bowtell, Estrid Høgdall, Francisco J Candido Dos Reis, Helen Steed, Ian G Campbell, Jacek Gronwald, Javier Benítez, Jennifer M Koziak, Jenny Chang-Claude, Kirsten B Moysich, Linda E Kelemen, Linda S Cook, Marc T Goodman, María José García, Peter A Fasching, Stefan Kommoss, Suha Deen, Susanne K Kjaer, Usha Menon, James D Brenton, Paul D P Pharoah, Georgia Chenevix-Trench, David G Huntsman, Stacey J Winham, Martin Köbel, Susan J Ramus
Importance: Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune control of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8+ TILs by histotype and in relation to other clinical factors. Objective: To define the prognostic role of CD8+ TILs in epithelial ovarian cancer. Design, Setting, and Participants: This was a multicenter observational, prospective survival cohort study of the Ovarian Tumor Tissue Analysis Consortium...
October 12, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29029385/analyses-of-germline-variants-associated-with-ovarian-cancer-survival-identify-functional-candidates-at-the-1q22-and-19p12-outcome-loci
#12
Dylan M Glubb, Sharon E Johnatty, Michael C J Quinn, Tracy A O'Mara, Jonathan P Tyrer, Bo Gao, Peter A Fasching, Matthias W Beckmann, Diether Lambrechts, Ignace Vergote, Digna R Velez Edwards, Alicia Beeghly-Fadiel, Javier Benitez, Maria J Garcia, Marc T Goodman, Pamela J Thompson, Thilo Dörk, Matthias Dürst, Francesmary Modungo, Kirsten Moysich, Florian Heitz, Andreas du Bois, Jacobus Pfisterer, Peter Hillemanns, Beth Y Karlan, Jenny Lester, Ellen L Goode, Julie M Cunningham, Stacey J Winham, Melissa C Larson, Bryan M McCauley, Susanne Krüger Kjær, Allan Jensen, Joellen M Schildkraut, Andrew Berchuck, Daniel W Cramer, Kathryn L Terry, Helga B Salvesen, Line Bjorge, Penny M Webb, Peter Grant, Tanja Pejovic, Melissa Moffitt, Claus K Hogdall, Estrid Hogdall, James Paul, Rosalind Glasspool, Marcus Bernardini, Alicia Tone, David Huntsman, Michelle Woo, Aocs Group, Anna deFazio, Catherine J Kennedy, Paul D P Pharoah, Stuart MacGregor, Georgia Chenevix-Trench
We previously identified associations with ovarian cancer outcome at five genetic loci. To identify putatively causal genetic variants and target genes, we prioritized two ovarian outcome loci (1q22 and 19p12) for further study. Bioinformatic and functional genetic analyses indicated that MEF2D and ZNF100 are targets of candidate outcome variants at 1q22 and 19p12, respectively. At 19p12, the chromatin interaction of a putative regulatory element with the ZNF100 promoter region correlated with candidate outcome variants...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29029097/impact-of-three-doses-of-vitamin-d3-on-serum-25-oh-d-deficiency-and-insufficiency-in-at-risk-schoolchildren
#13
Jennifer M Sacheck, Maria I Van Rompay, Virginia R Chomitz, Christina D Economos, Misha Eliasziw, Elizabeth Goodman, Catherine M Gordon, Michael F Holick
Objective: We investigated the daily dose of vitamin D needed to achieve serum 25-hydroxyvitamin D [25(OH)D] sufficiency among schoolchildren at-risk for deficiency. Study Design: The Daily D Health Study was a randomized double-blind vitamin D supplementation trial among racially/ethnically diverse schoolchildren (n=685) in the northeastern U.S. Children were supplemented with vitamin D3 at 600, 1000, or 2000 IU/day for six months. Measurements included serum 25(OH)D at baseline (Oct-Dec), 3 months (Jan-March), 6 months (April-June), and 12 months (6 months post-supplementation)...
September 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29018588/do-chain-pharmacies-perform-better-than-independent-pharmacies-evidence-from-a-standardised-patient-study-of-the-management-of-childhood-diarrhoea-and-suspected-tuberculosis-in-urban-india
#14
Rosalind Miller, Catherine Goodman
INTRODUCTION: Pharmacies and drug stores are frequently patients' first point of care in many low-income and middle-income countries, but their practice is often poor. Pharmacy retailing in India has traditionally been dominated by local, individually owned shops, but recent years have seen the growth of pharmacy chains. In theory, lower-powered profit incentives and self-regulation to preserve brand identity may lead to higher quality in chain stores. In practice, this has been little studied...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/28960578/the-impact-of-a-mosquito-net-voucher-subsidy-programme-on-incremental-ownership-the-case-of-the-tanzania-national-voucher-scheme
#15
Luke Harman, Catherine Goodman, Andrew Dorward
The subsidisation of mosquito nets has been widely used to increase ownership in countries where malaria represents a public health problem. However, an important question that has not been addressed empirically is how far net subsidy programmes increase ownership above the level that would have prevailed in the absence of the subsidy (i.e., incremental ownership). This study addresses that gap by investigating the impact of a large-scale mosquito net voucher subsidy--the Tanzania National Voucher Scheme (TNVS)--on short-term demand for unsubsidised commercial nets, estimating a household demand model with nationally representative household survey data...
September 29, 2017: Health Economics
https://www.readbyqxmd.com/read/28926469/a-survey-of-glucocorticoid-adverse-effects-and-benefits-in-rheumatic-diseases-the-patient-perspective
#16
Rachel J Black, Susan M Goodman, Carlee Ruediger, Susan Lester, Sarah L Mackie, Catherine L Hill
OBJECTIVE: The aim of this study was to explore, from the patient's perspective, the beneficial and adverse effects (AEs) of glucocorticoids (GCs) in patients with rheumatic diseases, to be used in the development of a patient-reported outcome measure. METHODS: A cross-sectional survey, capturing benefits and AEs of GC use, was administered to 2 groups of patients: (1) those attending a tertiary rheumatology clinic with various rheumatic diseases who had used GCs within the past year and (2) patients from the Hospital for Special Surgery rheumatoid arthritis database...
September 19, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28923948/cross-scale-effects-of-neural-interactions-during-human-neocortical-seizure-activity
#17
Tahra L Eissa, Koen Dijkstra, Christoph Brune, Ronald G Emerson, Michel J A M van Putten, Robert R Goodman, Guy M McKhann, Catherine A Schevon, Wim van Drongelen, Stephan A van Gils
Small-scale neuronal networks may impose widespread effects on large network dynamics. To unravel this relationship, we analyzed eight multiscale recordings of spontaneous seizures from four patients with epilepsy. During seizures, multiunit spike activity organizes into a submillimeter-sized wavefront, and this activity correlates significantly with low-frequency rhythms from electrocorticographic recordings across a 10-cm-sized neocortical network. Notably, this correlation effect is specific to the ictal wavefront and is absent interictally or from action potential activity outside the wavefront territory...
October 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28911328/devolution-and-its-effects-on-health-workforce-and-commodities-management-early-implementation-experiences-in-kilifi-county-kenya
#18
Benjamin Tsofa, Catherine Goodman, Lucy Gilson, Sassy Molyneux
BACKGROUND: Decentralisation is argued to promote community participation, accountability, technical efficiency, and equity in the management of resources, and has been a recurring theme in health system reforms for several decades. In 2010, Kenya passed a new constitution that introduced 47 semi-autonomous county governments, with substantial transfer of responsibility for health service delivery from the central government to these counties. Focusing on two key elements of the health system, Human Resources for Health (HRH) and Essential Medicines and Medical Supplies (EMMS) management, we analysed the early implementation experiences of this major governance reform at county level...
September 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28911325/how-does-decentralisation-affect-health-sector-planning-and-financial-management-a-case-study-of-early-effects-of-devolution-in-kilifi-county-kenya
#19
Benjamin Tsofa, Sassy Molyneux, Lucy Gilson, Catherine Goodman
BACKGROUND: A common challenge for health sector planning and budgeting has been the misalignment between policies, technical planning and budgetary allocation; and inadequate community involvement in priority setting. Health system decentralisation has often been promoted to address health sector planning and budgeting challenges through promoting community participation, accountability, and technical efficiency in resource management. In 2010, Kenya passed a new constitution that introduced 47 semi-autonomous devolved county governments, and a substantial transfer of responsibility for healthcare from the central government to these counties...
September 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28857972/are-you-making-an-impact-evaluating-the-population-health-impact-of-community-benefit-programs
#20
Catherine M Rains, Greta Todd, Nicole Kozma, Melody S Goodman
CONTEXT: The Patient Protection and Affordable Care Act includes a change to the IRS 990 Schedule H, requiring nonprofit hospitals to submit a community health needs assessment every 3 years. Such health care entities are challenged to evaluate the effectiveness of community benefit programs addressing the health needs identified. OBJECTIVE: In an effort to determine the population health impact of community benefit programs in 1 hospital outreach department, researchers and staff conducted an impact evaluation to develop priority areas and overarching goals along with program- and department-level objectives...
August 29, 2017: Journal of Public Health Management and Practice: JPHMP
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