keyword
https://read.qxmd.com/read/38472345/prediction-and-detection-of-side-effects-severity-following-covid-19-and-influenza-vaccinations-utilizing-smartwatches-and-smartphones
#1
JOURNAL ARTICLE
Yosi Levi, Margaret L Brandeau, Erez Shmueli, Dan Yamin
Vaccines stand out as one of the most effective tools in our arsenal for reducing morbidity and mortality. Nonetheless, public hesitancy towards vaccination often stems from concerns about potential side effects, which can vary from person to person. As of now, there are no automated systems available to proactively warn against potential side effects or gauge their severity following vaccination. We have developed machine learning (ML) models designed to predict and detect the severity of post-vaccination side effects...
March 12, 2024: Scientific Reports
https://read.qxmd.com/read/38464320/association-analysis-between-an-epigenetic-alcohol-risk-score-and-blood-pressure
#2
Helena Bui, Amena Keshawarz, Mengyao Wang, Mikyeong Lee, Scott M Ratliff, Lisha Lin, Kira S Birditt, Jessica D Faul, Annette Peters, Christian Gieger, Thomas Delerue, Sharon L R Kardia, Wei Zhao, Xiuqing Guo, Jie Yao, Jerome I Rotter, Dan Liu, Juliana F Tavares, Gökhan Pehlivan, Monique M B Breteler, Irma Karabegovic, Carolina Ochoa-Rosales, Trudy Voortman, Mohsen Ghanbari, Joyce B J van Meurs, Mohamed Kamal Nasr, Marcus Dörr, Hans J Grabe, Stephanie J London, Alexander Teumer, Melanie Waldenberger, David R Weir, Jennifer A Smith, Daniel Levy, Jiantao Ma, Chunyu Liu
Epigenome-wide association studies have revealed multiple DNA methylation sites (CpGs) associated with alcohol consumption, an important lifestyle risk factor for cardiovascular diseases. We generated an alcohol consumption epigenetic risk score (ERS) based on previously reported 144 alcohol-associated CpGs and examined the association of the ERS with systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension (HTN) in 3,898 Framingham Heart Study (FHS) participants. We found an association of alcohol intake with the ERS in the meta-analysis with 0...
March 2, 2024: medRxiv
https://read.qxmd.com/read/38329894/sensitization-of-meningeal-afferents-to-locomotion-related-meningeal-deformations-in-a-migraine-model
#3
JOURNAL ARTICLE
Andrew S Blaeser, Jun Zhao, Arthur U Sugden, Simone Carneiro-Nascimento, Mark L Andermann, Dan Levy
Migraine headache is hypothesized to involve the activation and sensitization of trigeminal sensory afferents that innervate the cranial meninges. To better understand migraine pathophysiology and improve clinical translation, we used two-photon calcium imaging via a closed cranial window in awake mice to investigate changes in the responses of meningeal afferent fibers using a preclinical model of migraine involving cortical spreading depolarization (CSD). A single CSD episode caused a seconds-long wave of calcium activation that propagated across afferents and along the length of individual afferents...
February 8, 2024: ELife
https://read.qxmd.com/read/38300202/hybrid-magnetic-resonance-positron-emission-tomography-is-associated-with-cardiac-related-outcomes-in-cardiac-sarcoidosis
#4
JOURNAL ARTICLE
Maria Giovanna Trivieri, Philip M Robson, Vittoria Vergani, Gina LaRocca, Angelica M Romero-Daza, Ronan Abgral, Ana Devesa, Levi-Dan Azoulay, Nicolas A Karakatsanis, Aditya Parikh, Christia Panagiota, Anna Palmisano, Louis DePalo, Helena L Chang, Joseph H Rothstein, Rima A Fayad, Marc A Miller, Valentin Fuster, Jagat Narula, Marc R Dweck, Adam Morgenthau, Adam Jacobi, Maria Padilla, Jason C Kovacic, Zahi A Fayad
BACKGROUND: Imaging with late gadolinium enhancement (LGE) magnetic resonance (MR) and 18 F-fluorodeoxyglucose (18 F-FDG) PET allows complementary assessment of myocardial injury and disease activity and has shown promise for improved characterization of active cardiac sarcoidosis (CS) based on the combined positive imaging outcome, MR(+)PET(+). OBJECTIVES: This study aims to evaluate qualitative and quantitative assessments of hybrid MR/PET imaging in CS and to evaluate its association with cardiac-related outcomes...
January 20, 2024: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/38284488/distinct-specificities-of-the-hemk2-protein-methyltransferase-in-methylation-of-glutamine-and-lysine-residues
#5
JOURNAL ARTICLE
Sara Weirich, Gizem T Ulu, Thyagarajan T Chandrasekaran, Jana Kehl, Jasmin Schmid, Franziska Dorscht, Margarita Kublanovsky, Dan Levy, Albert Jeltsch
The HEMK2 protein methyltransferase has been described as glutamine methyltransferase catalyzing ERF1-Q185me1 and lysine methyltransferase catalyzing H4K12me1. Methylation of two distinct target residues is unique for this class of enzymes. To understand the specific catalytic adaptations of HEMK2 allowing it to master this chemically challenging task, we conducted a detailed investigation of the substrate sequence specificities of HEMK2 for Q- and K-methylation. Our data show that HEMK2 prefers methylation of Q over K at peptide and protein level...
February 2024: Protein Science
https://read.qxmd.com/read/38260412/association-analysis-of-mitochondrial-dna-heteroplasmic-variants-methods-and-application
#6
Xianbang Sun, Katia Bulekova, Jian Yang, Meng Lai, Achilleas N Pitsillides, Xue Liu, Yuankai Zhang, Xiuqing Guo, Qian Yong, Laura M Raffield, Jerome I Rotter, Stephen S Rich, Goncalo Abecasis, April P Carson, Ramachandran S Vasan, Joshua C Bis, Bruce M Psaty, Eric Boerwinkle, Annette L Fitzpatrick, Claudia L Satizabal, Dan E Arking, Jun Ding, Daniel Levy, Chunyu Liu
We rigorously assessed a comprehensive association testing framework for heteroplasmy, employing both simulated and real-world data. This framework employed a variant allele fraction (VAF) threshold and harnessed multiple gene-based tests for robust identification and association testing of heteroplasmy. Our simulation studies demonstrated that gene-based tests maintained an appropriate type I error rate at α=0.001. Notably, when 5% or more heteroplasmic variants within a target region were linked to an outcome, burden-extension tests (including the adaptive burden test, variable threshold burden test, and z-score weighting burden test) outperformed the sequence kernel association test (SKAT) and the original burden test...
January 13, 2024: medRxiv
https://read.qxmd.com/read/38230336/beneficial-effects-of-control-iq-automated-insulin-delivery-in-basal-bolus-and-basal-only-insulin-users-with-type-2-diabetes
#7
JOURNAL ARTICLE
Carol J Levy, Dan Raghinaru, Yogish C Kudva, Keta Pandit, Thomas Blevins, Luis Casaubon, Donna Desjardins, Camilla M Levister, Grenye O'Malley, Corey Reid, John Lum, Craig Kollman, Roy W Beck
The t:slim X2 insulin pump with Control-IQ technology (Control-IQ) advanced hybrid closed-loop automated insulin delivery system was evaluated in this prospective single-arm trial. Thirty adults with type 2 diabetes using the Control-IQ system showed substantial glycemic improvement with no increase in hypoglycemia. Mean time in range (70-180 mg/dL) improved 15%, representing an increase of 3.6 hours/day, and mean glucose decreased by 22 mg/dL.
2024: Clinical Diabetes: a Publication of the American Diabetes Association
https://read.qxmd.com/read/38195980/smaller-total-and-subregional-cerebellar-volumes-in-posttraumatic-stress-disorder-a-mega-analysis-by-the-enigma-pgc-ptsd-workgroup
#8
JOURNAL ARTICLE
Ashley A Huggins, C Lexi Baird, Melvin Briggs, Sarah Laskowitz, Ahmed Hussain, Samar Fouda, Courtney Haswell, Delin Sun, Lauren E Salminen, Neda Jahanshad, Sophia I Thomopoulos, Dick J Veltman, Jessie L Frijling, Miranda Olff, Mirjam van Zuiden, Saskia B J Koch, Laura Nawjin, Li Wang, Ye Zhu, Gen Li, Dan J Stein, Jonathan Ipser, Soraya Seedat, Stefan du Plessis, Leigh L van den Heuvel, Benjamin Suarez-Jimenez, Xi Zhu, Yoojean Kim, Xiaofu He, Sigal Zilcha-Mano, Amit Lazarov, Yuval Neria, Jennifer S Stevens, Kerry J Ressler, Tanja Jovanovic, Sanne J H van Rooij, Negar Fani, Anna R Hudson, Sven C Mueller, Anika Sierk, Antje Manthey, Henrik Walter, Judith K Daniels, Christian Schmahl, Julia I Herzog, Pavel Říha, Ivan Rektor, Lauren A M Lebois, Milissa L Kaufman, Elizabeth A Olson, Justin T Baker, Isabelle M Rosso, Anthony P King, Isreal Liberzon, Mike Angstadt, Nicholas D Davenport, Scott R Sponheim, Seth G Disner, Thomas Straube, David Hofmann, Rongfeng Qi, Guang Ming Lu, Lee A Baugh, Gina L Forster, Raluca M Simons, Jeffrey S Simons, Vincent A Magnotta, Kelene A Fercho, Adi Maron-Katz, Amit Etkin, Andrew S Cotton, Erin N O'Leary, Hong Xie, Xin Wang, Yann Quidé, Wissam El-Hage, Shmuel Lissek, Hannah Berg, Steven Bruce, Josh Cisler, Marisa Ross, Ryan J Herringa, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine L Larson, Terri A deRoon-Cassini, Carissa W Tomas, Jacklynn M Fitzgerald, Jennifer Urbano Blackford, Bunmi O Olatunji, William S Kremen, Michael J Lyons, Carol E Franz, Evan M Gordon, Geoffrey May, Steven M Nelson, Chadi G Abdallah, Ifat Levy, Ilan Harpaz-Rotem, John H Krystal, Emily L Dennis, David F Tate, David X Cifu, William C Walker, Elizabeth A Wilde, Ian H Harding, Rebecca Kerestes, Paul M Thompson, Rajendra Morey
Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when considering subregions that differentially map on to motor, cognitive, and affective functions. In a sample of 4215 adults (PTSD n = 1642; Control n = 2573) across 40 sites from the ENIGMA-PGC PTSD working group, we employed a new state-of-the-art deep-learning based approach for automatic cerebellar parcellation to obtain volumetric estimates for the total cerebellum and 28 subregions...
January 10, 2024: Molecular Psychiatry
https://read.qxmd.com/read/38177345/multi-ancestry-genome-wide-association-study-of-major-depression-aids-locus-discovery-fine-mapping-gene-prioritization-and-causal-inference
#9
JOURNAL ARTICLE
Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, Daniel F Levey, Dora Koller, Gita A Pathak, Nastassja Koen, Kuang Lin, Mark J Adams, Miguel E Rentería, Yanzhe Feng, J Michael Gaziano, Dan J Stein, Heather J Zar, Megan L Campbell, David A van Heel, Bhavi Trivedi, Sarah Finer, Andrew McQuillin, Nick Bass, V Kartik Chundru, Hilary C Martin, Qin Qin Huang, Maria Valkovskaya, Chia-Yi Chu, Susan Kanjira, Po-Hsiu Kuo, Hsi-Chung Chen, Shih-Jen Tsai, Yu-Li Liu, Kenneth S Kendler, Roseann E Peterson, Na Cai, Yu Fang, Srijan Sen, Laura J Scott, Margit Burmeister, Ruth J F Loos, Michael H Preuss, Ky'Era V Actkins, Lea K Davis, Monica Uddin, Agaz H Wani, Derek E Wildman, Allison E Aiello, Robert J Ursano, Ronald C Kessler, Masahiro Kanai, Yukinori Okada, Saori Sakaue, Jill A Rabinowitz, Brion S Maher, George Uhl, William Eaton, Carlos S Cruz-Fuentes, Gabriela A Martinez-Levy, Adrian I Campos, Iona Y Millwood, Zhengming Chen, Liming Li, Sylvia Wassertheil-Smoller, Yunxuan Jiang, Chao Tian, Nicholas G Martin, Brittany L Mitchell, Enda M Byrne, Swapnil Awasthi, Jonathan R I Coleman, Stephan Ripke, Tamar Sofer, Robin G Walters, Andrew M McIntosh, Renato Polimanti, Erin C Dunn, Murray B Stein, Joel Gelernter, Cathryn M Lewis, Karoline Kuchenbaecker
Most genome-wide association studies (GWAS) of major depression (MD) have been conducted in samples of European ancestry. Here we report a multi-ancestry GWAS of MD, adding data from 21 cohorts with 88,316 MD cases and 902,757 controls to previously reported data. This analysis used a range of measures to define MD and included samples of African (36% of effective sample size), East Asian (26%) and South Asian (6%) ancestry and Hispanic/Latin American participants (32%). The multi-ancestry GWAS identified 53 significantly associated novel loci...
January 4, 2024: Nature Genetics
https://read.qxmd.com/read/38140680/factors-associated-with-virological-failure-in-first-line-antiretroviral-therapy-in-patients-diagnosed-with-hiv-1-between-2010-and-2018-in-israel
#10
JOURNAL ARTICLE
Tali Wagner, Itzchak Levy, Daniel Elbirt, Eduardo Shahar, Karen Olshtain-Pops, Hila Elinav, Michal Chowers, Valery Istomin, Klaris Riesenberg, Dikla Geva, Neta S Zuckerman, Marina Wax, Rachel Shirazi, Yael Gozlan, Natasha Matus, Shirley Girshengorn, Rotem Marom, Ella Mendelson, Orna Mor, Dan Turner
Despite the progress in contemporary antiretroviral therapy (ART) and the continuous changes in treatment guidelines, virological failure (VF) is still an ongoing concern. The goal of this study was to assess factors related to VF after first-line ART. A longitudinal cohort retrospective study of individuals on first-line ART diagnosed with HIV-1 in 2010-2018 and followed-up for a median of two years was conducted. Demographics, baseline and longitudinal CD4 counts, treatment regimens, adherence and VF were recorded...
December 15, 2023: Viruses
https://read.qxmd.com/read/38106101/mitochondrial-dna-copy-number-variation-in-asthma-risk-severity-and-exacerbations
#11
Weiling Xu, Yun Soo Hong, Bo Hu, Suzy A A Comhair, Allison J Janocha, Joe G Zein, Ruoying Chen, Deborah A Meyers, David T Mauger, Victor E Ortega, Eugene R Bleecker, Mario Castro, Loren C Denlinger, John V Fahy, Elliot Israel, Bruce D Levy, Nizar N Jarjour, Wendy C Moore, Sally E Wenzel, Benjamin Gaston, Chunyu Liu, Dan E Arking, Serpil C Erzurum
RATIONALE: Although airway oxidative stress and inflammation are central to asthma pathogenesis, there is limited knowledge of the relationship of asthma risk, severity, or exacerbations to mitochondrial dysfunction, which is pivotal to oxidant generation and inflammation. OBJECTIVES: We investigated whether mitochondrial DNA copy number (mtDNA-CN) as a measure of mitochondrial function is associated with asthma diagnosis, severity, oxidative stress, and exacerbations...
December 5, 2023: medRxiv
https://read.qxmd.com/read/38032283/high-repetition-rate-relativistic-laser-solid-plasma-interaction-platform-featuring-simultaneous-particle-and-radiation-detection
#12
JOURNAL ARTICLE
Jaismeen Kaur, Marie Ouillé, Dan Levy, Louis Daniault, Axel Robbes, Neil Zaïm, Alessandro Flacco, Eyal Kroupp, Victor Malka, Stefan Haessler, Rodrigo Lopez-Martens
We report on a uniquely designed high repetition rate relativistic laser-solid-plasma interaction platform, featuring the first simultaneous measurement of emitted high-order harmonics, relativistic electrons, and low divergence proton beams. This versatile setup enables detailed parametric studies of the particle and radiation spatio-spectral beam properties under a wide range of controlled interaction conditions, such as pulse duration and plasma density gradient. Its array of complementary diagnostics unlocks the potential to unravel interdependencies among the observables and should aid in further understanding the complex collective dynamics at play during laser-plasma interactions and in optimizing the secondary beam properties for applications...
November 1, 2023: Review of Scientific Instruments
https://read.qxmd.com/read/38017161/examining-the-association-between-posttraumatic-stress-disorder-and-disruptions-in-cortical-networks-identified-using-data-driven-methods
#13
JOURNAL ARTICLE
Jin Yang, Ashley A Huggins, Delin Sun, C Lexi Baird, Courtney C Haswell, Jessie L Frijling, Miranda Olff, Mirjam van Zuiden, Saskia B J Koch, Laura Nawijn, Dick J Veltman, Benjamin Suarez-Jimenez, Xi Zhu, Yuval Neria, Anna R Hudson, Sven C Mueller, Justin T Baker, Lauren A M Lebois, Milissa L Kaufman, Rongfeng Qi, Guang Ming Lu, Pavel Říha, Ivan Rektor, Emily L Dennis, Christopher R K Ching, Sophia I Thomopoulos, Lauren E Salminen, Neda Jahanshad, Paul M Thompson, Dan J Stein, Sheri M Koopowitz, Jonathan C Ipser, Soraya Seedat, Stefan du Plessis, Leigh L van den Heuvel, Li Wang, Ye Zhu, Gen Li, Anika Sierk, Antje Manthey, Henrik Walter, Judith K Daniels, Christian Schmahl, Julia I Herzog, Israel Liberzon, Anthony King, Mike Angstadt, Nicholas D Davenport, Scott R Sponheim, Seth G Disner, Thomas Straube, David Hofmann, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine L Larson, Terri A deRoon-Cassini, Jennifer U Blackford, Bunmi O Olatunji, Evan M Gordon, Geoffrey May, Steven M Nelson, Chadi G Abdallah, Ifat Levy, Ilan Harpaz-Rotem, John H Krystal, Rajendra A Morey, Aristeidis Sotiras
Posttraumatic stress disorder (PTSD) is associated with lower cortical thickness (CT) in prefrontal, cingulate, and insular cortices in diverse trauma-affected samples. However, some studies have failed to detect differences between PTSD patients and healthy controls or reported that PTSD is associated with greater CT. Using data-driven dimensionality reduction, we sought to conduct a well-powered study to identify vulnerable networks without regard to neuroanatomic boundaries. Moreover, this approach enabled us to avoid the excessive burden of multiple comparison correction that plagues vertex-wise methods...
November 28, 2023: Neuropsychopharmacology
https://read.qxmd.com/read/37972256/cgrp-signalling-in-migraine-time-to-look-downstream
#14
EDITORIAL
Dan Levy
No abstract text is available yet for this article.
November 16, 2023: Brain
https://read.qxmd.com/read/37969302/prolonged-air-leak-after-lung-surgery-prevalent-complication-without-a-perfect-solution
#15
EDITORIAL
Moshe Lapidot, Dan Levy Faber, Raphael Bueno
No abstract text is available yet for this article.
October 31, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/37943274/co2-laser-matricectomy-for-the-treatment-of-pincer-nail-deformity-a-retrospective-cohort-study
#16
JOURNAL ARTICLE
Igor Snast, Maya Engler Markowitz, Vlad Uvaidov, Eran Galili, Yaron Ben Mordehai, Yonatan Edel, Asaf Olshinka, Dan Slodownik, Eran Sharon, Moshe Lapidoth, Assi Levi
BACKGROUND: Pincer nail deformity (PND) is a common toenail disorder characterized by transverse over-curvature of the nail plate. It can cause severe pain, chronic inflammation, and recurrent infections. Both conservative and surgical treatment options carry different disadvantages of limited efficacy, high recurrence rate, and poor cosmetic outcome. The study aimed to evaluate the safety and effectiveness of carbon dioxide (CO2) laser matricectomy for the treatment of PND. METHODS: The database of the laser unit of a tertiary medical center was retrospectively searched for all patients who were diagnosed with PND in 2016-2022 and treated with lateral and/or medial matricectomy using CO2 laser...
November 1, 2023: Journal of Drugs in Dermatology: JDD
https://read.qxmd.com/read/37935487/prescription-ranitidine-use-and-population-exposure-in-6-canadian-provinces-1996-to-2019-a-serial-cross-sectional-analysis
#17
JOURNAL ARTICLE
Adrian R Levy, David Stock, J Michael Paterson, Hala Tamim, Dan Chateau, Jacqueline Quail, Paul E Ronksley, Greg Carney, Pauline Reynier, Laura Targownik
BACKGROUND: Ranitidine was the most prescribed histamine-2 receptor antagonist (H2 RA) in Canada when recalled in 2019 because of potential carcinogenicity. We sought to compare geographic and temporal patterns in use of prescription ranitidine and 3 other HRAs and estimated population exposure to ranitidine in 6 provinces between 1996 and 2019. METHODS: This population-based serial cross-sectional study used prescription claims for H2 RAs dispensed from community pharmacies in Nova Scotia, Ontario, Manitoba, Saskatchewan, Alberta and British Columbia...
2023: CMAJ Open
https://read.qxmd.com/read/37930717/the-natural-history-of-disability-and-caregiving-before-and-after-long-term-care-entry
#18
COMMENT
Kenneth Lam, Irena Cenzer, Cari R Levy, Dan D Matlock, Alexander K Smith, Kenneth E Covinsky
IMPORTANCE: Many older persons move into long-term care facilities (LTCFs) due to disability and insufficient home caregiving options. However, the extent of disability and caregiving provided around the time of entry is unknown. OBJECTIVE: To quantitatively describe disability and caregiving before and after LTCF entry, comparing nursing home (NH), assisted living (AL), and independent living (IL) entrants. DESIGN, SETTING, AND PARTICIPANTS: A longitudinal cohort study using prospectively collected annual data from the National Health and Aging Trends Study from 2011 to 2020 including participants in the continental US...
December 1, 2023: JAMA Internal Medicine
https://read.qxmd.com/read/37905118/determinants-of-mosaic-chromosomal-alteration-fitness
#19
Yash Pershad, Taralynn Mack, Hannah Poisner, Yasminka A Jakubek, Adrienne M Stilp, Braxton D Mitchell, Joshua P Lewis, Eric Boerwinkle, Ruth J Loos, Nathalie Chami, Zhe Wang, Kathleen Barnes, Nathan Pankratz, Myriam Fornage, Susan Redline, Bruce M Psaty, Joshua C Bis, Ali Shojaie, Edwin K Silverman, Michael H Cho, Jeong Yun, Dawn DeMeo, Daniel Levy, Andrew Johnson, Rasika Mathias, Margaret Taub, Donna Arnett, Kari North, Laura M Raffield, April Carson, Margaret F Doyle, Stephen S Rich, Jerome I Rotter, Xiuqing Guo, Nancy Cox, Dan M Roden, Nora Franceschini, Pinkal Desai, Alex Reiner, Paul L Auer, Paul Scheet, Siddhartha Jaiswal, Joshua S Weinstock, Alexander G Bick
Clonal hematopoiesis (CH) is characterized by the acquisition of a somatic mutation in a hematopoietic stem cell that results in a clonal expansion. These driver mutations can be single nucleotide variants in cancer driver genes or larger structural rearrangements called mosaic chromosomal alterations (mCAs). The factors that influence the variations in mCA fitness and ultimately result in different clonal expansion rates are not well-understood. We used the Passenger-Approximated Clonal Expansion Rate (PACER) method to estimate clonal expansion rate for 6,381 individuals in the NHLBI TOPMed cohort with gain, loss, and copy-neutral loss of heterozygosity mCAs...
October 21, 2023: medRxiv
https://read.qxmd.com/read/37841474/case-report-blindness-associated-with-learedius-learedi-trematode-infection-in-a-green-sea-turtle-chelonia-mydas-of-the-northern-red-sea
#20
Danny Morick, Vanessa M Bachmann, Eli Shemesh, Ana Maria Botero-Anug, Ziv Zemach-Shamir, Zahi Aizenberg, Nadav Davidovich, Daphne W Goldberg, Gaston Kan, Ron Ofri, Dan Tchernov, Yaniv Levy
Spirorchiid blood flukes are widespread in sea turtles, causing disease and mortality in their populations, with high prevalence in several ocean basins. Besides being leading parasitic causes of sea turtle strandings in several parts of the world, these infectious agents can cause endocarditis, vasculitis, thrombosis, miliary egg granulomas, and aneurysms, which ultimately may compromise the survival of green sea turtles. More severe cases may also result in multifocal granulomatous meningitis or pneumonia, both of which can be fatal...
2023: Frontiers in Veterinary Science
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