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JOURNAL ARTICLE
Luciano Agati
No abstract text is available yet for this article.
April 2024: Echocardiography
#22
REVIEW
Apoorva Doshi, Haresh Gandhi, Kunal N Patel, Monil Majmundar, Rajkumar Doshi
The 2019 ACC/AHA guidelines regarding low-dose aspirin in primary prevention of Atherosclerotic Cardiovascular Disease (ASCVD) indicate increased risk of bleeding without a net benefit. Coronary Artery Calcium (CAC) score could be used to guide aspirin therapy in high-risk individuals without increased risk of bleeding. With this systematic review, we aim to analyse studies that have investigated the role of CAC in primary prevention with aspirin. Four relevant studies were identified and the primary outcomes of interest were bleeding events and major adverse cardiac events...
March 26, 2024: American Journal of Cardiology
#23
REVIEW
Grzegorz K Jakubiak
Cardiac troponin serum concentration is the primary marker used for the diagnosis of acute coronary syndrome. Moreover, the measurement of cardiac troponin concentration is important for risk stratification in patients with pulmonary embolism. The cardiac troponin level is also a general marker of myocardial damage, regardless of etiology. The purpose of this study is to conduct a literature review and present the most important information regarding the current state of knowledge on the cardiac troponin serum concentration in patients with chronic cardiovascular disease (CVD), as well as on the relationships between cardiac troponin serum concentration and features of subclinical cardiovascular dysfunction...
February 21, 2024: Journal of Personalized Medicine
#24
JOURNAL ARTICLE
Rares Ilie Orzan, Rares Ioan Gligor, Renata Agoston, Carmen Cionca, Alexandru Zlibut, Raluca Pais, Andrada Seicean, Lucia Agoston-Coldea
In this single-center cross-sectional study on patients undergoing coronary computed tomography angiography (CCTA), we assessed the prognostic significance of metabolic dysfunction associated steatotic liver disease (MASLD), metabolic syndrome (MetS), and CCTA-derived parameters for predicting major adverse cardiovascular events (MACE). Over a mean follow-up of 26.9 months, 2038 patients were analyzed, with 361 (17.7%) experiencing MACE. MASLD was associated with a higher MACE incidence (25.90% vs. 14.71% without MASLD, p < 0...
February 26, 2024: Journal of Cardiovascular Development and Disease
#25
JOURNAL ARTICLE
Aryoung Kim, Danbee Kang, Sung Chul Choi, Juhee Cho, Dong Hyun Sinn, Geum-Youn Gwak
BACKGROUND & AIMS: A new nomenclature, Steatotic Liver Disease (SLD), has been proposed by consensus with sub-classifications and requires evidence-based validation. We assessed whether the presence and severity of SLD, as well as its sub-classifications, are associated with the progression of coronary atherosclerosis. METHODS: This longitudinal cohort study included 13,811 adults who participated in repeated regular health screening examinations between January 1, 2004 and December 31, 2021 that included assessments of their coronary artery calcium (CAC) scores...
2024: PloS One
#26
JOURNAL ARTICLE
Nina P Haag, Arwed E Michael, Simon Lennartz, Christoph Panknin, Julius H Niehoff, Jan Borggrefe, Iram Shahzadi, Alex Zwanenburg, Jan Robert Kroeger
Background Coronary artery calcium scoring (CACS) for coronary artery disease requires true noncontrast (TNC) CT alongside contrast-enhanced coronary CT angiography (CCTA). Photon-counting CT provides an algorithm (PureCalcium) for reconstructing virtual noncontrast images from CCTA specifically for CACS. Purpose To assess CACS differences based on PureCalcium images derived from contrast-enhanced photon-counting CCTA compared with TNC images and evaluate the impact of these differences on the clinically relevant classification of patients into plaque burden groups...
March 2024: Radiology
#27
JOURNAL ARTICLE
M M Dobrolinska, R A Jukema, S G M van Velzen, P A van Diemen, M J W Greuter, N H J Prakken, N R van der Werf, P G Raijmakers, R H J A Slart, P Knaapen, I Isgum, I Danad
PURPOSE: Firstly, to validate automatically and visually scored coronary artery calcium (CAC) on low dose CT (LDCT) scans with a dedicated calcium scoring CT (CSCT) scan. Secondly, to assess the added value of CAC scored from LDCT scans acquired during [15O]-water-PET myocardial perfusion imaging (MPI) on prediction of major adverse cardiac events (MACE). METHODS: 572 consecutive patients with suspected coronary artery disease, who underwent [15O]-water-PET MPI with LDCT and a dedicated CSCT scan were included...
March 25, 2024: European Heart Journal Cardiovascular Imaging
#28
JOURNAL ARTICLE
Violeta Hyseni, Shpend Elezi, Bujar Gjikolli, Aurora Bakalli
OBJECTIVE: Long-standing diabetes mellitus is often associated with cardiovascular complications. We aimed to evaluate the presence, extent and composition of subclinical atherosclerotic plaques in coronary arteries by Computed Tomography in patients with newly diagnosed type 2 diabetes mellitus (NDT2DM), and to identify the predictors. METHODS: In this study 101 consecutive patients with NDT2DM were included. Patients were categorized into five groups based on their Coronary Artery Calcium Score (CACS) ranging from 0, 0-10, 11-100, 101-400 to >400...
2024: Diabetes & Vascular Disease Research
#29
JOURNAL ARTICLE
Dong Li, Song Shou Mao, Matthew J Budoff
UNLABELLED: We evaluated the relationship of bone mineral density (BMD) by computed tomography (CT), to predict fractures in a multi-ethnic population. We demonstrated that vertebral and hip fractures were more likely in those patients with low BMD. This is one of the first studies to demonstrate that CT BMD derived from thoracic vertebrae can predict future hip and vertebral fractures. PURPOSE/INTRODUCTION: Osteoporosis affects an enormous number of patients, of all races and both sexes, and its prevalence increases as the population ages...
March 22, 2024: Osteoporosis International
#30
JOURNAL ARTICLE
Rasmus Carter-Storch, Emma Le Nezet, Mulham Ali, Andréanne Powers, Amal Haujir, Karolanne Demers, Christian Couture, Éric Dumont, Sylvain Trahan, Sylvain Pagé, François Dagenais, Philippe Pibarot, Jordi S Dahl, Marie-Annick Clavel
BACKGROUND: Angiotensin receptor blockers (ARBs) may slow down the progression of aortic stenosis (AS), through their antifibrotic effect. Females present more valvular fibrosis than males, thus ARBs may have more effect in females. Our aim was to assess the impact of ARBs on the remodeling of the aortic valve in males and females. METHODS: We included patients who had an aortic valve replacement± coronary bypass grafting between 2006-2013. Patients with missing echocardiographic or histologic data were excluded...
March 20, 2024: Canadian Journal of Cardiology
#31
JOURNAL ARTICLE
Sonoo Mizuiri, Yoshiko Nishizawa, Kazuomi Yamashita, Toshiki Doi, Aiko Okubo, Kenichi Morii, Koji Usui, Michiko Arita, Takayuki Naito, Kenichiro Shigemoto, Takao Masaki
AIM: We studied the effects of overhydration (OH), Kt/Vurea and β2-microglobulin (β2-MG) on coronary artery calcification and mortality in patients undergoing haemodialysis (HD). METHODS: The Agatston coronary artery calcium score (CACS), postdialysis body composition using bioimpedance analysis, single-pool Kt/Vurea and predialysis β2-MG at baseline were assessed and followed up for 3 years in patients undergoing HD. We performed logistic regression analyses for a CACS ≥400 and Cox proportional hazard analyses for all-cause and cardiovascular mortality...
March 21, 2024: Nephrology
#32
REVIEW
Leon M Bischoff, Julian A Luetkens
BACKGROUND: Early treatment of cardiovascular risk factors and characterization of coronary plaques is essential to collect prognostic information about coronary artery disease (CAD) and prevent cardiovascular events. OBJECTIVES: Discussion of the most important risk factors of CAD, basic diagnostic of CAD, prevention, and prognostic factors of CAD with focus on cardiac computed tomography (CT). MATERIALS AND METHODS: Prevalence and prognostic impact of CAD risk factors; description of specific assessment of risk profiles; estimation of pretest probability; conventional prevention of CAD; prognostic assessment of CAD using the Calcium Scoring and coronary CT angiography...
March 21, 2024: Radiologie (Heidelb)
#33
JOURNAL ARTICLE
Rafael Escate, Teresa Padró, Leopoldo Pérez de Isla, Francisco Fuentes, Rodrigo Alonso, Pedro Mata, Lina Badimon
BACKGROUND AND AIMS: Premature atherosclerotic cardiovascular disease (CVD) is a clinic characteristic of familial hypercholesterolemia (FH). Coronary calcium score (CCS) is a highly used imaging modality to evidence atherosclerotic plaque burden. microRNAs (miRNAs) are non-coding RNAs that epigenetically regulate gene expression. Here, we investigated whether CCS associates with a specific miRNA-signature in FH-patients. METHODS: Patients with genetic diagnosis of FH (N = 86) from the nationwide SAFEHEART-cohort were investigated by computed tomography angiography imaging and classified depending on the presence of coronary calcification in FH-CCS (+) and FH-CCS (-) groups by the Agatston score...
March 8, 2024: Atherosclerosis
#34
JOURNAL ARTICLE
Matthias Weidlich, Bernd Hamm, Lars-Arne Schaafs, Thomas Elgeti
PURPOSE: This retrospective study aimed to investigate the epicardial fat volume in cardiac computed tomography (CT), its relationship with cardiac arrhythmias, and its correlation with the coronary artery disease reporting and data system (CAD-RADS) score. MATERIAL AND METHODS: Ninety-six patients who underwent CT coronary angiography (CTCA) were included in this study. Patient data, including demographic information, clinical history, and imaging data were collected retrospectively...
2024: Polish Journal of Radiology
#35
JOURNAL ARTICLE
George Simantirakis, Costas J Hourdakis, Maria Kalathaki, Vasiliki Liotsou, Magda Nikolaou, Christos Pafilis, Zoi Thrapsanioti, Panagiotis Tritakis, Eleftheria Carinou
The escalating use of Computed Tomography (CT) imaging necessitates establishment and periodic revision of Diagnostic Reference Levels (DRLs) to ensure patient protection optimization. This paper presents the outcomes of a national survey conducted from 2019 to 2022, focusing on revising DRLs for adult CT examinations. Dosimetric data from 127 scanners in 120 medical facilities, representing 25% of the country's CT scanners, were collected, emphasizing geographic distribution and technology representation. Τhe parameters used for DRLs were the CTDIvol and the DLP of a typical acquisition of the region of interest (scan DLP)...
March 16, 2024: European Journal of Radiology
#36
JOURNAL ARTICLE
Sonoo Mizuiri, Yoshiko Nishizawa, Kazuomi Yamashita, Toshiki Doi, Aiko Okubo, Kenichi Morii, Koji Usui, Michiko Arita, Takayuki Naito, Kenichiro Shigemoto, Takao Masaki
AIM: The effects of iron on vascular calcification in rats and vascular smooth muscle cells were recently reported, but clinical studies on iron and vascular calcification are scant. We studied the associations of absolute iron deficiency, coronary artery calcification and mortality in patients with maintenance haemodialysis (MHD). METHODS: Transferrin saturation (TSAT), ferritin, mean corpuscular haemoglobin (MCH) and Agatston coronary artery calcium score (CACS) were studied at baseline in MHD patients and followed up for 3 years...
March 19, 2024: Nephrology
#37
JOURNAL ARTICLE
Jingcheng Hu, Guangyu Hao, Jialiang Xu, Ximing Wang, Meng Chen
BACKGROUND: Coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) patients often presents diffuse lesions, with extensive calcification, and it is time-consuming to measure coronary artery calcium score (CACS). OBJECTIVES: To explore the predictive ability of deep learning (DL)-based CACS for obstructive CAD and hemodynamically significant CAD in T2DM. METHODS: 469 T2DM patients suspected of CAD who accepted CACS scan and coronary CT angiography between January 2013 and December 2020 were enrolled...
March 30, 2024: Heliyon
#38
JOURNAL ARTICLE
Raman Puri, Manish Bansal, Vimal Mehta, P Barton Duell, Nathan D Wong, S S Iyengar, Dinesh Kalra, Devaki R Nair, Navin C Nanda, Jagat Narula, P Deedwania, Jamal Yusuf, Jamshed J Dalal, Sadanand Shetty, Vinod M Vijan, Rajeev Agarwala, Soumitra Kumar, Kris Vijay, Aziz Khan, Gurpreet Singh Wander, P C Manoria, S K Wangnoo, Viswanathan Mohan, Shashank R Joshi, Balbir Singh, Prafulla Kerkar, Rajesh Rajput, D Prabhakar, Abdul Hamid Zargar, Banshi Saboo, Ravi R Kasliwal, Saumitra Ray, Sandeep Bansal, M U Rabbani, Shibba Takkar Chhabra, Sarat Chandra, Neil Bardoloi, Narasaraju Kavalipati, Immaneni Sathyamurthy, Kunal Mahajan, Akshya Pradhan, N N Khanna, Rajesh Khadgawat, Preeti Gupta, Milan C Chag, Ashu Gupta, A Murugnathan, S N Narasingan, Sundeep Upadhyaya, Vinod Mittal, Rashida Patanwala Melinkeri, Madhur Yadav, M Raseed Mubarak, K K Pareek, Pradeep Kumar Dabla, Rashmi Nanda, J C Mohan
OBJECTIVE: In 2016, the Lipid Association of India (LAI) developed a cardiovascular risk assessment algorithm and defined low-density lipoprotein cholesterol (LDL-C) goals for prevention of atherosclerotic cardiovascular disease (ASCVD) in Indians. The recent refinements in the role of various risk factors and subclinical atherosclerosis in prediction of ASCVD risk necessitated updating the risk algorithm and treatment goals. METHODS: The LAI core committee held twenty-one meetings and webinars from June 2022 to July 2023 with experts across India and critically reviewed the latest evidence regarding the strategies for ASCVD risk prediction and the benefits and modalities for intensive lipid lowering...
February 8, 2024: Journal of Clinical Lipidology
#39
JOURNAL ARTICLE
Deep learning analysis of epicardial adipose tissue to predict cardiovascular risk in heavy smokers.
Borek Foldyna, Ibrahim Hadzic, Roman Zeleznik, Marcel C Langenbach, Vineet K Raghu, Thomas Mayrhofer, Michael T Lu, Hugo J W L Aerts
BACKGROUND: Heavy smokers are at increased risk for cardiovascular disease and may benefit from individualized risk quantification using routine lung cancer screening chest computed tomography. We investigated the prognostic value of deep learning-based automated epicardial adipose tissue quantification and compared it to established cardiovascular risk factors and coronary artery calcium. METHODS: We investigated the prognostic value of automated epicardial adipose tissue quantification in heavy smokers enrolled in the National Lung Screening Trial and followed for 12...
March 13, 2024: Commun Med (Lond)
#40
EDITORIAL
Ian M Graham
No abstract text is available yet for this article.
March 13, 2024: European Journal of Preventive Cardiology
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