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Malaria fever

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https://www.readbyqxmd.com/read/28931399/principles-practices-and-knowledge-of-clinicians-when-assessing-febrile-children-a-qualitative-study-in-kenya
#1
Anneka M Hooft, Kelsey Ripp, Bryson Ndenga, Francis Mutuku, David Vu, Kimberly Baltzell, Linnet N Masese, John Vulule, Dunstan Mukoko, A Desiree LaBeaud
BACKGROUND: Clinicians in low resource settings in malaria endemic regions face many challenges in diagnosing and treating febrile illnesses in children. Given the change in WHO guidelines in 2010 that recommend malaria testing prior to treatment, clinicians are now required to expand the differential when malaria testing is negative. Prior studies have indicated that resource availability, need for additional training in differentiating non-malarial illnesses, and lack of understanding within the community of when to seek care play a role in effective diagnosis and treatment...
September 20, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28930168/a-review-of-the-composition-of-the-essential-oils-and-biological-activities-of-angelica-species
#2
REVIEW
Kandasamy Sowndhararajan, Ponnuvel Deepa, Minju Kim, Se Jin Park, Songmun Kim
A number of Angelica species have been used in traditional systems of medicine to treat many ailments. Especially, essential oils (EOs) from the Angelica species have been used for the treatment of various health problems, including malaria, gynecological diseases, fever, anemia, and arthritis. EOs are complex mixtures of low molecular weight compounds, especially terpenoids and their oxygenated compounds. These components deliver specific fragrance and biological properties to essential oils. In this review, we summarized the chemical composition and biological activities of EOs from different species of Angelica...
September 20, 2017: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/28927422/proximity-to-vector-breeding-site-and-risk-of-plasmodium-vivax-infection-a-prospective-cohort-study-in-rural-ethiopia
#3
Alexander Nissen, Jackie Cook, Eskindir Loha, Bernt Lindtjørn
BACKGROUND: Despite falling incidence and mortality since the turn of the century, malaria remains an important global health challenge. In the future fight against malaria, greater emphasis will have to be placed on understanding and addressing malaria caused by the Plasmodium vivax parasite. Unfortunately, due to years of neglect and underfunding, there are currently many gaps in knowledge of P. vivax malaria. The aims of the present study were to explore the association between distance to vector breeding site and P...
September 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28924518/clinical-spectrum-of-chikungunya-in-pakistan
#4
Syeda Naqvi, Shehroz Bashir, Chintan Rupareliya, Abdullah Shams, Pirthvi Raj Giyanwani, Zeeshan Ali, Faiza Qamar, Vijesh Kumar, Vikash Talib
Background Chikungunya fever is a pandemic disease caused by an arthropod-borne chikungunya virus (CHIKV). The virus spreads through mosquitoes. This mosquito induced viral illness is clinically suspected on symptoms from fever and severe polyarthralgia. The recent outbreak of chikungunya was reported in November 2016 in the metropolitan city Karachi, Pakistan. We emphasis on the awareness of the etiology and vector control to prevent serious consequences. Method A total number of 1275 patients were included in this cross-sectional study...
July 6, 2017: Curēus
https://www.readbyqxmd.com/read/28923020/caretakers-understanding-of-malaria-use-of-insecticide-treated-net-and-care-seeking-behavior-for-febrile-illness-of-their-children-in-ethiopia
#5
Zewdie Birhanu, Yemane Ye-Ebiyo Yihdego, Delenasaw Yewhalaw
BACKGROUND: Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers' knowledge on malaria, use of Long Lasting Insecticide Treated Nets (LLINs) and care-seeking behavior for their children's illness in different malaria transmission settings of Ethiopia. METHODS: Data were collected from 709 caretakers of children of 2-9 years of age during in 2016. A standard questionnaire was used to assess caretakers' perceptions of malaria, use of LLIN and care seeking behavior for febrile illness of children aged 2-9 years...
September 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28922657/methods-employed-in-cytofluorometric-assessment-of-eryptosis-the-suicidal-erythrocyte-death
#6
Mohamed Jemaà, Myriam Fezai, Rosi Bissinger, Florian Lang
Suicidal erythrocyte death or eryptosis contributes to or even accounts for anemia in a wide variety of clinical conditions, such as iron deficiency, dehydration, hyperphosphatemia, vitamin D excess, chronic kidney disease (CKD), hemolytic-uremic syndrome, diabetes, hepatic failure, malignancy, arteriitis, sepsis, fever, malaria, sickle-cell disease, beta-thalassemia, Hb-C and G6PD-deficiency, Wilsons disease, as well as advanced age. Moreover, eryptosis is triggered by a myriad of xenobiotics and endogenous substances including cytotoxic drugs and uremic toxins...
September 1, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28922459/therapeutic-plasma-exchange-in-the-treatment-of-complicated-plasmodium-falciparum-malaria-a-case-report
#7
Tsong-Yih Ou, Cheng-Yen Chuang, Chun-Da Chen, Chung-Yi Cheng
Severe falciparum malaria is associated with multiple organ dysfunction and a high rate of fatal outcome. Malaria is a world-wide disease in tropical areas through the bites of vector mosquitoes. Parasitic protozoans introduced by the mosquito's saliva to the blood travel to the liver then mature and reproduce. In humans, malaria is caused by Plasmodium falciparum, P. malariae, P. ovale, P. vivax, and P. knowlesi, and P. falciparum causes most deaths. Typical malaria symptoms include fever, chills, fatigue, headache, nausea, and vomiting...
September 18, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28919170/importation-of-infectious-diseases-are-increasing-in-south-korea-association-with-international-travels
#8
Young-June Choe, Seung-Ah Choe, Sung-Il Cho
BACKGROUND: International travel has an important role in transmission of emerging infectious diseases. We described the imported infectious diseases in Korea from 2003 to 2012, and to analyze association of travels with the change in the incidences. METHODS: We used National Notifiable Disease Surveillance System to investigate the incidence of salmonellosis, shigellosis, malaria, and dengue. Data from Korea Tourism Organization was used to describe the inbound and outbound travelers by their age group, gender, and purpose of travel...
September 15, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28916443/aq-13-an-investigational-antimalarial-versus-artemether-plus-lumefantrine-for-the-treatment-of-uncomplicated-plasmodium-falciparum-malaria-a-randomised-phase-2-non-inferiority-clinical-trial
#9
Ousmane A Koita, Lansana Sangaré, Haiyan D Miller, Aliou Sissako, Moctar Coulibaly, Trevor A Thompson, Saharé Fongoro, Youssouf Diarra, Mamadou Ba, Ababacar Maiga, Boubakar Diallo, David M Mushatt, Frances J Mather, Jeffrey G Shaffer, Asif H Anwar, Donald J Krogstad
BACKGROUND: Chloroquine was used for malaria treatment until resistant Plasmodium falciparum was identified. Because 4-aminoquinolines with modified side chains, such as AQ-13, are active against resistant parasites, we compared AQ-13 against artemether plus lumefantrine for treatment of uncomplicated P falciparum malaria. METHODS: We did a randomised, non-inferiority trial. We screened men (≥18 years) with uncomplicated malaria in Missira (northeast Mali) and Bamako (capital of Mali) for eligibility (≥2000 asexual P falciparum parasites per μL of blood)...
September 12, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28910810/concurrent-infection-with-plasmodium-vivax-and-the-dengue-and-chikungunya-viruses-in-a-paediatric-patient-from-new-delhi-india-in-2016
#10
Ayesha Tazeen, Mohd Abdullah, Malik Hisamuddin, Sher Ali, Irshad H Naqvi, Hirday N Verma, Anwar Ahmed, Shama Parveen
Dengue and chikungunya fevers are transmitted by the common mosquito vector Aedes and malaria by Anopheles. Concurrent infections are reported due to co-circulation of these pathogens, especially in endemic regions. We report a rare case of triple infection with 3 arthropod-borne pathogens (Plasmodium vivax and the dengue and chikungunya viruses) in a 3-year-old child from New Delhi, India, in August 2016. The viruses were identified by RT-PCR and the parasite by microscopy and antigen detection. The dengue virus serotype 3 sequence was clustered in the genotype III by the phylogenetic analysis...
September 15, 2017: Intervirology
https://www.readbyqxmd.com/read/28893674/seroepidemiology-of-leptospirosis-among-febrile-patients-in-a-rapidly-growing-suburban-slum-and-a-flood-vulnerable-rural-district-in-mozambique-2012-2014-implication-for-the-management-of-fever
#11
Policarpo Ribeiro, Nilesh Bhatt, Sádia Ali, Vanessa Monteiro, Edmilson da Silva, Ilana Teruszkin Balassiano, Carolina Aquino, Nilsa de de Deus, Onelia Guiliche, Argentina Felisbela Muianga, Pascoal Jorge Alho, Virginia Lara Evaristo, Ivan Manhiça, Marco Medeiros, Eduardo Samo Gudo
OBJECTIVE: Leptospirosis, is one of most widespread zoonosis in the world and is caused by spirochetes of the genus Leptospira. In Mozambique, the disease is heavily ignored and its epidemiology is unknown. The objective of this study was to investigate occurrence of leptospirosis in febrile patients. METHODS: A cross-sectional study was conducted among febrile patients between June 2012 and September 2015. A total of 373 paired samples were drawn from febrile patients, of whom 208 were from Caia District Hospital (rural setting) in Sofala province and 165 were from Polana Caniço General Hospital (suburban setting) in Maputo city...
September 8, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28885461/vaccinations-and-malaria-chemoprophylaxis-of-adolescents-traveling-from-greece-to-international-destinations-a-nine-year-prospective-study
#12
Helena C Maltezou, Androula Pavli, Kalliopi Theodoridou, Panos Katerelos, Athina Spilioti, Anastasia Tedoma, Ioanna Lymperi, Maria Theodoridou
BACKGROUND: There are few publications focusing on vaccination and malaria chemoprophylaxis in adolescent travelers. We assessed pre-travel vaccinations and malaria chemoprophylaxis of adolescents 12-18 old traveling from Greece to international destinations. METHODS: We prospectively studied 239 adolescents 12-18 years old during 2008-2016. A standard questionnaire was used to collect data. RESULTS: Adolescents sought pre-travel services at a mean of 24...
September 6, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28879600/infections-and-the-kidney-a-tale-from-the-tropics
#13
Nivedita Kamath, Arpana Iyengar
Tropical infections are caused by a variety of bacteria, viruses and parasitic organisms across varying geographical regions and are more often reported in adults than in children. Most of the infections are acute, presenting as a febrile illness with involvement of multiple organ systems, including the kidney. The gamut of renal manifestations extends from asymptomatic urinary abnormalities to acute kidney injury and-albeit rarely-chronic kidney disease. Tropical infections can involve the glomerular, tubulointerstitial and vascular compartments of the kidney...
September 6, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28879175/computer-vision-malaria-diagnostic-systems-progress-and-prospects
#14
REVIEW
Joseph Joel Pollak, Arnon Houri-Yafin, Seth J Salpeter
Accurate malaria diagnosis is critical to prevent malaria fatalities, curb overuse of antimalarial drugs, and promote appropriate management of other causes of fever. While several diagnostic tests exist, the need for a rapid and highly accurate malaria assay remains. Microscopy and rapid diagnostic tests are the main diagnostic modalities available, yet they can demonstrate poor performance and accuracy. Automated microscopy platforms have the potential to significantly improve and standardize malaria diagnosis...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28879148/implementation-of-broad-screening-with-ebola-rapid-diagnostic-tests-in-for%C3%A3-cariah-guinea
#15
Frantz Jean Louis, Jennifer Y Huang, Yacouba K Nebie, Lamine Koivogui, Gayatri Jayaraman, Nadine Abiola, Amanda Vansteelandt, Mary C Worrel, Judith Shang, Louise B Murphy, David L Fitter, Barbara J Marston, Lise Martel
BACKGROUND: Laboratory-enhanced surveillance is critical for rapidly detecting the potential re-emergence of Ebola virus disease. Rapid diagnostic tests (RDT) for Ebola antigens could expand diagnostic capacity for Ebola virus disease. OBJECTIVES: The Guinean National Coordination for Ebola Response conducted a pilot implementation to determine the feasibility of broad screening of patients and corpses with the OraQuick(®) Ebola RDT. METHODS: The implementation team developed protocols and trained healthcare workers to screen patients and corpses in Forécariah prefecture, Guinea, from 15 October to 30 November 2015...
2017: African Journal of Laboratory Medicine
https://www.readbyqxmd.com/read/28874536/microrna-277-targets-insulin-like-peptides-7-and-8-to-control-lipid-metabolism-and-reproduction-in-aedes-aegypti-mosquitoes
#16
Lin Ling, Vladimir A Kokoza, Changyu Zhang, Emre Aksoy, Alexander S Raikhel
Hematophagous female mosquitoes transmit numerous devastating human diseases, including malaria, dengue fever, Zika virus, and others. Because of their obligatory requirement of a vertebrate blood meal for reproduction, these mosquitoes need a lot of energy; therefore, understanding the molecular mechanisms linking metabolism and reproduction is of particular importance. Lipids are the major energy store providing the fuel required for host seeking and reproduction. They are essential components of the fat body, a metabolic tissue that is the insect analog of vertebrate liver and adipose tissue...
September 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28864166/artemisinin-permeability-via-caco-2-cells-increases-after-simulated-digestion-of-artemisia-annua-leaves
#17
Matthew R Desrosiers, Pamela J Weathers
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia annua has been used for > 2000yrs to treat fever and is more recently known for producing the important antimalarial drug, artemisinin. AIM OF THE STUDY: Artemisinin combination therapies (ACTs) are effective for treating malaria, but are often unavailable to those in need. Dried leaves of A. annua (DLA) have recently been studied as a cost effective alternative to traditional ACTs. DLA was shown to dramatically increase oral bioavailability compared to pure artemisinin, so more investigation into the mechanisms causing this increased bioavailability is needed...
August 31, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28859342/developing-research-in-infectious-and-tropical-diseases-in-africa-the-paradigm-of-senegal
#18
Cheikh Sokhna, Oumar Gaye, Ogobara Doumbo
Infectious diseases represent one of the greatest potential barriers to achievement of the third Sustainable Development Goals in African countries and around the world because they continue to pose major public health challenges. The surveillance of infectious diseases has recently assumed greater importance in most African countries, both because of the emergence of infectious diseases and because strains of pathogens that cause tuberculosis, malaria, cholera, dysentery, and pneumonia have developed resistance to common and inexpensive antimicrobial drugs...
August 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28851358/treatment-seeking-patterns-for-malaria-in-pharmacies-in-five-sub-saharan-african-countries
#19
Joël Ladner, Ben Davis, Etienne Audureau, Joseph Saba
BACKGROUND: Artemisinin-based combination therapy (ACT) is recommended as the first-line anti-malarial treatment strategy in sub-Saharan African countries. WHO policy recommends parasitological confirmation by microscopy or rapid diagnostic test (RDT) in all cases of suspected malaria prior to treatment. Gaps remain in understanding the factors that influence patient treatment-seeking behaviour and anti-malarial drug purchase decisions in the private sector. The objective of this study was to identify patient treatment-seeking behaviour in Ghana, Kenya, Nigeria, Tanzania, and Uganda...
August 29, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28829731/high-prevalence-of-anemia-but-low-level-of-iron-deficiency-in-preschool-children-during-a-low-transmission-period-of-malaria-in-rural-kivu-democratic-republic-of-the-congo
#20
Esto Bahizire, Paluku Bahwere, Philippe Donnen, P Lundimu Tugirimana, Serge Balol'ebwami, Michèle Dramaix, Chouchou Nfundiko, Raphaël Chirimwami, Kanigula Mubagwa
Anemia is a worldwide public health concern especially in preschool children in developing countries and iron deficiency (ID) is generally assumed to cause at least 50% of the cases. However, data on this contribution are scarce. To close this gap, we determined in 2013 the contribution of ID in the etiology of anemia and measured others factors associated to noniron deficiency anemia (NIDA) in 900 preschool children randomly selected during a two-stage cluster nutritional survey in the Miti-Murhesa health zone, in eastern Democratic Republic of the Congo...
August 2017: American Journal of Tropical Medicine and Hygiene
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