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Vestibular disorders

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https://www.readbyqxmd.com/read/28938275/inpatient-treatment-of-patients-admitted-for-dizziness-a-population-based-healthcare-research-study-on-epidemiology-diagnosis-treatment-and-outcome
#1
Vera Renner, Katharina Geißler, Daniel Boeger, Jens Buentzel, Dirk Esser, Kerstin Hoffmann, Peter Jecker, Andreas Mueller, Gerald Radtke, Hubertus Axer, Orlando Guntinas-Lichius
OBJECTIVE: To determine inpatient treatment rates of patients with dizziness with focus on diagnostics, treatment and outcome. STUDY DESIGN: Retrospective population-based study. SETTING: Inpatients in the federal state Thuringia in 2014. PATIENTS: All 1,262 inpatients (62% females, median age: 61 yr) treated for inpatient dizziness were included. MAIN OUTCOME MEASURES: The association between analyzed parameters and probability of improvement and recovery was tested using univariable and multivariable statistics...
September 21, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28932680/brain-responses-to-vestibular-pain-and-its-anticipation-in-women-with-genito-pelvic-pain-penetration-disorder
#2
Els Pazmany, Huynh Giao Ly, Leen Aerts, Michiko Kano, Sophie Bergeron, Johan Verhaeghe, Ronald Peeters, Jan Tack, Patrick Dupont, Paul Enzlin, Lukas Van Oudenhove
OBJECTIVE: In DSM-5, pain-related fear during anticipation of vaginal penetration is a diagnostic criterion of Genito-Pelvic Pain/Penetration Disorder (GPPPD). We aimed to investigate subjective and brain responses during anticipatory fear and subsequent induction of vestibular pain in women with GPPPD. METHODS: Women with GPPPD (n = 18) and age-matched healthy controls (HC) (n = 15) underwent fMRI scanning during vestibular pain induction at individually titrated pain threshold after a cued anticipation period...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28926944/coach-cv-the-seven-clinical-phenotypes-of-concussion
#3
Neil Craton, Haitham Ali, Stephane Lenoski
Our understanding of the diverse physiological manifestations of concussion is changing rapidly. This has an influence on the clinical assessment of patients who have sustained a concussion. The 2017 Consensus Statement on Concussion in Sport states that numerous post-injury clinical findings, such as cognitive deficits, post-traumatic headaches, dizziness, difficulties with oculomotor function, and depression have all been associated with a poorer prognosis in concussed patients. This demonstrates that there are several potential clinical manifestations after head injury warranting clinical evaluation...
September 16, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28924861/role-of-bdnf-and-neurotrophic-receptors-in-human-inner-ear-development
#4
L Johnson Chacko, M J F Blumer, E Pechriggl, H Rask-Andersen, W Dietl, A Haim, H Fritsch, R Glueckert, J Dudas, A Schrott-Fischer
The expression patterns of the neurotrophin, brain-derived neurotrophic factor, BDNF, and the neurotrophic receptors-p75NTR and Trk receptors-in the developing human fetal inner ear between the gestational weeks (GW) 9 to 12 are examined via in situ hybridization and immunohistochemistry. BDNF mRNA expression was highest in the cochlea at GW 9 but declined in the course of development. In contrast to embryonic murine specimens, a decline in BDNF expression from the apical to the basal turn of the cochlea could not be observed...
September 19, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28919878/postural-control-in-bilateral-vestibular-failure-its-relation-to-visual-proprioceptive-vestibular-and-cognitive-input
#5
Andreas Sprenger, Jann F Wojak, Nico M Jandl, Christoph Helmchen
Patients with bilateral vestibular failure (BVF) suffer from postural and gait unsteadiness with an increased risk of falls. The aim of this study was to elucidate the differential role of otolith, semicircular canal (SSC), visual, proprioceptive, and cognitive influences on the postural stability of BVF patients. Center-of-pressure displacements were recorded by posturography under six conditions: target visibility; tonic head positions in the pitch plane; horizontal head shaking; sensory deprivation; dual task; and tandem stance...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28917252/stereotactic-radiosurgery-of-the-brain-a-review-of-common-indications
#6
Philip Gilbo, Isabella Zhang, Jonathan Knisely
Over the past half-century since Lars Leksell first utilized radiation to address deep and difficult to treat lesions of the central nervous system (CNS), intracranial stereotactic radiosurgery (SRS) has become an increasingly valued tool in the hands of neurosurgeons and radiation oncologists. Following developments in medical imaging and radiation technology, radiosurgery has evolved from its first application in movement disorders to widespread use for a varied range of malignant and benign conditions. SRS remains a powerful, minimally invasive instrument that offers additional options for intervention to a diverse patient population...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28911803/sensory-overload-and-imbalance-resting-state-vestibular-connectivity-in-ptsd-and-its-dissociative-subtype
#7
Sherain Harricharan, Andrew A Nicholson, Maria Densmore, Jean Théberge, Margaret C McKinnon, Richard W J Neufeld, Ruth A Lanius
BACKGROUND: The vestibular system integrates multisensory information to monitor one's bodily orientation in space, and is influenced by interoceptive awareness. Post-traumatic stress disorder (PTSD) involves typically alterations in interoceptive and bodily self-awareness evidenced by symptoms of hyperarousal, as well as of emotional detachment, including emotional numbing, depersonalization, and derealization. These alterations may disrupt vestibular multisensory integration between the brainstem (vestibular nuclei) and key vestibular cortical regions (parieto-insular vestibular cortex, prefrontal cortex)...
September 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28900754/surgery-versus-stereotactic-radiosurgery-for-the-treatment-of-multiple-meningiomas-in-neurofibromatosis-type-2-illustrative-case-and-systematic-review
#8
REVIEW
Thien Nguyen, Lawrance K Chung, John P Sheppard, Nikhilesh S Bhatt, Cheng Hao Jacky Chen, Carlito Lagman, Tania Kaprealian, Percy Lee, Phioanh L Nghiemphu, Isaac Yang
Neurofibromatosis type 2 (NF2) is a genetic neoplastic disorder that presents with hallmark bilateral vestibular schwannomas and multiple meningiomas. Though the current standard of care for meningiomas includes surgery, the multiplicity of meningiomas in NF2 patients renders complete resection of all developing lesions infeasible. Stereotactic radiosurgery (SRS) may be a viable non-invasive therapeutic alternative to surgery. We describe a particularly challenging case in a 39-year-old male with over 120 lesions who underwent more than 30 surgical procedures, and review the literature...
September 13, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28894988/how-tandem-gait-stumbled-into-the-neurological-exam-a-review
#9
Jason Margolesky, Carlos Singer
Tandem gait testing is an integral part of the neurological exam. It is informative in a wide variety of disorders ranging from cerebellar disease to vestibular and peripheral neuropathies, parkinsonism, and other neurodegenerative conditions. We discuss the history and development of tandem gait testing as well as its technique, utility, and limitations in the assessment of neurological conditions. Tandem gait has emerged as a tool in the assessment of cerebellar disease, Huntington disease, idiopathic Parkinson's disease, atypical parkinsonism, peripheral neuropathies, and vestibulopathies...
September 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28893717/secondary-surgical-decompression-of-the-inferior-alveolar-nerve-after-overfilling-of-endodontic-sealer-into-the-mandibular-canal-case-report-and-literature-review
#10
Anne-Victoire Bastien, Jérôme Adnot, Hervé Moizan, Émile Calenda, Olivier Trost
The authors report the case of a 43 year-old woman who underwent endodontic treatment of the right second mandibular molar with substantial extrusion of endodontic material into the mandibular canal. The patient presented at the Department of Oral and Maxillofacial Surgery with a persistent total anaesthesia of the lower lip and chin after two months. 2D panoramic view and 3D CT-scan examination highlighted the overfilling into the mandibular canal with a more than 50% stenosis of the canal and a consequently significant compression of the dental pedicle...
September 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28893312/the-validity-and-reliability-of-the-four-square-step-test-in-different-adult-populations-a-systematic-review
#11
Martha Moore, Karen Barker
BACKGROUND: The four square step test (FSST) was first validated in healthy older adults to provide a measure of dynamic standing balance and mobility. The FSST has since been used in a variety of patient populations. The purpose of this systematic review is to determine the validity and reliability of the FSST in these different adult patient populations. METHODS: The literature search was conducted to highlight all the studies that measured validity and reliability of the FSST...
September 11, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28891872/vertigo-in-vestibular-schwannoma-patients-due-to-other-pathologies
#12
Ronald Sahyouni, Omid Moshtaghi, Yarah M Haidar, Hossein Mahboubi, Afsheen Moshtaghi, Harrison W Lin, Hamid R Djalilian
OBJECTIVE: To report findings from a cohort of vestibular schwannoma (VS) patients presenting with vertigo from a secondary comorbid vestibular disorder; and to discuss management strategies for this subset of patients presenting with both episodic vertigo and VS. PATIENTS: All VS patients who presented with vertigo as the primary symptom from 2012 to 2015 and endorsing no other major complaints were examined. INTERVENTION: Treatment with migraine lifestyle and prophylactic therapy, or Epley maneuver...
September 7, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28885964/cervical-joint-position-sense-in-hypobaric-conditions-a-randomized-double-blind-controlled-trial
#13
Diana Bagaianu, Damien Van Tiggelen, N Duvigneaud, Veerle Stevens, Danny Schroyen, Dirk Vissenaeken, Gino D'Hondt, Laurent Pitance
Well-adapted motor actions require intact and well-integrated information from all of the sensory systems, specifically the visual, vestibular, and somatosensory systems, including proprioception. Proprioception is involved in the sensorimotor control by providing the central nervous system with an updated body schema of the biomechanical and spatial properties of the body parts. With regard to the cervical spine, proprioceptive information from joint and muscle mechanoreceptors is integrated with vestibular and visual feedback to control head position, head orientation, and whole body posture...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28884719/-vestibular-migraine-diagnostic-difficulties-and-treatment-optimization
#14
A V Li, E V Parkhomenko, A N Barinov
AIM: The study aimed at showing actual information about vestibular migraine and presenting different features of vestibular migraine for prevention of diagnostic mistakes and choosing an effective treatment. MATERIAL AND METHODS: Fifty patients with vestibular migraine were diagnosed according to the International Classification of Headache Disorders 3rd edition and examined in a neurological department. RESULTS: Problems with outpatient diagnosis and treatment were found...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28875382/-tumors-of-the-inner-ear-and-adjacent-structures
#15
REVIEW
J Schittenhelm
Tumors of the inner ear and adjacent structures often present with hearing loss, tinnitus and vertigo due to compression of the traversing cranial nerves. More than 90% of the tumors of the inner ear with or without expansion into the cerebellopontine angle are histologically diagnosed as vestibular schwannomas. Less common tumorous lesions include ectopic meningiomas located in the petrous bone, glomus tympanicum paragangliomas or endolymphatic sac tumors (ELST) originating in the vestibular recess. Most tumors are sporadic, but hereditary disorders have to be considered...
September 5, 2017: Der Pathologe
https://www.readbyqxmd.com/read/28874926/craniosacral-therapy-and-visceral-manipulation-a-new-treatment-intervention-for-concussion-recovery
#16
Gail Wetzler, Melinda Roland, Sally Fryer-Dietz, Dee Dettmann-Ahern
Background: Military service members and veterans face health issues related to traumatic brain injury (TBI), especially during combat, use of heavy equipment, and exposures to environmental hazards and explosives. There were 400,000 TBIs reported in deployed U.S. troops in 2012. Athletes are also subject to TBI. Studies have indicated that some manual therapies could be helpful for treating patients who have post-concussive syndrome. Objective: This case series report describes the effects of CranioSacral Therapy (CST), Visceral Manipulation (VM), and Neural Manipulation (NM) modalities for treating patients who have post-concussion syndrome...
August 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/28865839/ovemp-as-an-objective-indicator-of-successful-repositioning-maneuver
#17
Samir Asal, Osama Sobhy, Amany Balbaa
BACKGROUND AND OBJECTIVE: Benign paroxysmal positioning vertigo (BPPV) is the most common peripheral vestibular disorder. Canalolithiasis in the posterior semi-circular canal is the most common underlying pathology that can be treated effectively by repositioning maneuvers. Our hypothesis suggested that successful maneuvers can lead to repositioning of dislodged otoconia to the utricle. MATERIALS AND METHODS: Air conducted oVEMP, which is thought to originate from the contra-lateral utricular organ was measured in twenty patients with unilateral BPPV and we compared n1-p1 peak to peak amplitude of the affected ears in 3 separate intervals: on pre-treatment when typical nystagmus was confirmed, immediately after, and 1 week after repositioning maneuvers to assess change, if any, in amplitude...
August 30, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28854827/translation-and-validation-of-the-dizziness-handicap-inventory-in-greek-language
#18
Christos Nikitas, Dimitris Kikidis, Spyros Katsinis, Efthimios Kyrodimos, Athanasios Bibas
OBJECTIVE: The aim of the study was to test the reliability and validity of the Dizziness Handicap Inventory in the Greek language (DHI). DESIGN: This study was performed in a university tertiary centre. Internal consistency was estimated using Cronbach's alpha for the DHI, physical (DHI-P), functional (DHI-F) and emotional (DHI-E) subscale scores. Correlation between DHI (total and subscales) and the SOT (sensory organisation test) as well as correlation between the DHI and FGA (functional gait assessment) was tested using Spearman's correlation coefficient...
August 30, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28846792/computerized-dynamic-posturography-for-evaluating-dizziness-in-patients-with-scarred-orbital-content
#19
Nathan Shlamkovitch, Ephraim Eviatar, Haim Gavriel
Our objective was to assess the capability of computerized dynamic posturography (CDP) to evaluate dizziness in blind patients who lack corneoretinal potential. We performed a retrospective analysis of 2 young blind subjects with intraorbital scarring who complained of dizziness and underwent CDP. Tests were carried out at our center for balance disorders using the NeuroCom's EquiTest System version 4.0. CDP demonstrated vestibular dysfunction and revealed it to be severe. We conclude that CDP can serve as a potentially reliable tool for assessing dizziness in blind patients who have no corneoretinal potential...
August 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28835534/local-gene-therapy-durably-restores-vestibular-function-in-a-mouse-model-of-usher-syndrome-type-1g
#20
Alice Emptoz, Vincent Michel, Andrea Lelli, Omar Akil, Jacques Boutet de Monvel, Ghizlene Lahlou, Anaïs Meyer, Typhaine Dupont, Sylvie Nouaille, Elody Ey, Filipa Franca de Barros, Mathieu Beraneck, Didier Dulon, Jean-Pierre Hardelin, Lawrence Lustig, Paul Avan, Christine Petit, Saaid Safieddine
Our understanding of the mechanisms underlying inherited forms of inner ear deficits has considerably improved during the past 20 y, but we are still far from curative treatments. We investigated gene replacement as a strategy for restoring inner ear functions in a mouse model of Usher syndrome type 1G, characterized by congenital profound deafness and balance disorders. These mice lack the scaffold protein sans, which is involved both in the morphogenesis of the stereociliary bundle, the sensory antenna of inner ear hair cells, and in the mechanoelectrical transduction process...
September 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
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