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https://www.readbyqxmd.com/read/29344071/acetazolamide-a-new-treatment-for-visual-vertigo
#1
Ilya M Sluch, Michael S Elliott, Justin Dvorak, Kai Ding, Bradley K Farris
Visual vertigo is a disorder characterised by symptoms of dizziness, vertigo, unsteadiness, disorientation, and general discomfort induced by visual triggers. It is currently treated with vestibular rehabilitation therapy, with no effective pharmacotherapy available for treatment-resistant cases. The objective of this study was to evaluate the efficacy of oral acetazolamide in improving symptoms of visual vertigo. A comparative case series of adult patients clinically diagnosed with visual vertigo was conducted from January 1992 to May 2015...
December 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29336136/international-clinical-protocol-on-vestibular-disorders-dizziness
#2
Kostiantyn Trinus, Claus-Frenz Claussen
26-28 May at 43 Congress of Neurootological and Equilibriometric Society (Budapest, Hungary) International Clinical Protocol on Vestibular Disorders (Dizziness) being discussed and accepted as Consensus Document. Cochrane reports estimates that dizziness has prevalence of 22.9% in the last 12 months and an incidence of 3.1%. Only 1.8% of adults consulted a physician in the last 12 months. Cochrane reviews suggest that the evidence base for dizziness evaluation is weak, thus necessitates the creation of evidence-based document...
December 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/29336131/vestibular-schwannoma-and-ipsilateral-endolymphatic-hydrops-an-unusual-association
#3
Massimo Ralli, Antonio Greco, Giancarlo Altissimi, Rosaria Turchetta, Lucia Longo, Vittorio D'Aguanno, Mario Tombolini, Giancarlo Cianfrone, Marco de Vincentiis
Vestibular schwannoma and endolymphatic hydrops are two conditions that may present with similar audio-vestibular symptoms. The association of the two in the same patient represents an unusual finding that may lead clinicians to errors and delays in diagnosis and clinical management of affected subjects. We discuss the case of a patient with an intrameatal vestibular schwannoma reporting symptoms suggestive for ipsilateral endolymphatic hydrops. The patient presented with fluctuating hearing loss, tinnitus, and acute rotatory vertigo episodes, and underwent a full audiological evaluation and imaging of the brain with contrast-enhanced Magnetic Resonance Imaging...
December 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/29317827/optimal-management-of-cogan-s-syndrome-a-multidisciplinary-approach
#4
REVIEW
Vittorio D'Aguanno, Massimo Ralli, Marco de Vincentiis, Antonio Greco
Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and atypical variants. Typical CS manifests primarily with IK and hearing loss, whereas atypical CS usually presents with inflammatory ocular manifestations in association with audio-vestibular symptoms but mostly different Ménière-like symptoms and, more frequently, with systemic inflammation (70%), of which vasculitis is the pathogenic mechanism...
2018: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/29310507/inner-ear-test-battery-in-guinea-pig-models-a-review
#5
Yi-Ho Young
OBJECTIVE: This study reviewed the development of the inner ear test battery comprising auditory brainstem response (ABR), and caloric, ocular vestibular-evoked myogenic potential (oVEMP), and cervical vestibular-evoked myogenic potential (cVEMP) tests in guinea pig models at our laboratory over the last 20 years. Detailed description of the methodology for testing the small animals is also included. METHODS: Inner ear disorders, i.e. ototoxicity, noise exposure, or perilymph fistula were established in guinea pig models first...
January 8, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29307789/inner-ear-involvement-in-fabry-disease-clinical-and-audiometric-evaluation-of-a-large-cohort-of-patients-followed-in-a-reference-centre
#6
Jorge Rodrigues, Olga Azevedo, Nuno Sousa, Damião Cunha, Alexandre Mexedo, Rui Fonseca
BACKGROUND: Fabry disease (FD) is a lysosomal storage disorder (LSD) that involves the cochleovestibular system. Tinnitus and progressive sensorineural hearing loss are frequent complains. A stabilization of hearing function has been reported with enzyme replacement therapy (ERT). This study aims to characterize the inner ear involvement, identify factors associated to hearing loss and evaluate the effect of ERT on the hearing function of FD patients. METHODS: We reviewed the clinical records of patients with confirmed diagnosis of FD followed in a Reference Centre on LSD in the North of Portugal...
January 4, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29301160/-pharmacotherapy-of-vestibular-disorders-nystagmus-and-cerebellar-disorders
#7
K Feil, N Böttcher, O Kremmyda, C Muth, J Teufel, A Zwergal, T Brandt, M Strupp
There are currently different groups of drugs for the pharmacotherapy of vertigo, nystagmus and cerebellar disorders: antiemetics; anti-inflammatories, antimenieres, and antimigraineous medications and antidepressants, anticonvulsants, aminopyridines as well as acetyl-DL-leucine. In acute unilateral vestibulopathy, corticosteroids improve the recovery of peripheral vestibular function, but currently there is not sufficient evidence for a general recommendation. There is insufficient evidence to support the view that 16 mg t...
January 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29298650/potential-application-of-centrifuges-to-protect-the-cns-in-space-and-on-earth
#8
Yoshiki Takamatsu, Gilbert Ho, Yuki Shimizu, Shuei Sugama, Takato Takenouchi, Masaaki Waragai, Jianshe Wei, Makoto Hashimoto
BACKGROUND: Centrifuges are the principal means of generating physiological hypergravity and have been used for many medical purposes, including the therapy of psychiatric diseases and evaluation of vestibular system in the pilots. In particular, modern centrifuges have evolved into mechanically sophisticated precision instruments compared to primitive ones in old times, indicating that centrifuges might possess great potential in modern medicine. Indeed, studies are in progress to apply centrifuges to musculoskeletal degenerative diseases, such as osteoporosis and sarcopenia...
December 29, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29287036/benign-paroxysmal-positional-vertigo-bppv-in-children-and-adolescents-clinical-features-and-response-to-therapy-in-110-pediatric-patients
#9
Jacob R Brodsky, Sophie Lipson, Jared Wilber, Guangwei Zhou
OBJECTIVE: This study aimed to characterize the clinical features and outcomes of benign paroxysmal positional vertigo (BPPV) in the pediatric population. STUDY DESIGN: Retrospective case review. SETTING: Tertiary care center. PATIENTS: One hundred ten patients, aged 5 to 19 years old, diagnosed with BPPV. MAIN OUTCOME MEASURES: Patient demographics, comorbidities, canal involvement, response to treatment, and incidence of recurrence...
December 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29282699/dizziness-in-the-emergency-department-an-update-on-diagnosis
#10
Rainer Spiegel, Mark Kirsch, Christiane Rosin, Heiko Rust, Thomas Baumann, Raoul Sutter, Hergen Friedrich, Martina Göldlin, René Müri, Roger Kalla, Roland Bingisser, Georgios Mantokoudis
This review aims to assist emergency physicians in finding the underlying aetiology when a patient presents with dizziness to the emergency department. After reading this review, the emergency physician will be able to consider the most relevant differential diagnoses and have an idea about dangerous aetiologies that require immediate action. The emergency physician will also know what diagnostic steps need to be taken at what time, such as the three-component HINTS Test (Head Impulse, Nystagmus, and Test-of-Skew), which helps with distinguishing central from peripheral causes of the acute vestibular syndrome...
December 28, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29282523/amiodarone-associated-bilateral-vestibulopathy
#11
Robert Gürkov, Leonardo Manzari, Alexander Blödow, Angela Wenzel, Dusan Pavlovic, Leonal Luis
BACKGROUND: Bilateral vestibulopathy (BVP) is a debilitating disorder characterized by the hypofunction of both vestibular end organs or nerves. The most frequent identifiable causes of BVP are ototoxic drug effects, infectious and autoimmune disorders. The majority of cases, however, remain idiopathic. METHODS: Medical records of patients diagnosed with idiopathic BVP were examined in five dizziness clinics. RESULTS: We identified 126 patients with "idiopathic" BVP...
December 27, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29279722/current-diagnostic-procedures-for-diagnosing-vertigo-and-dizziness
#12
REVIEW
Leif Erik Walther
Vertigo is a multisensory syndrome that otolaryngologists are confronted with every day. With regard to the complex functions of the sense of orientation, vertigo is considered today as a disorder of the sense of direction, a disturbed spatial perception of the body. Beside the frequent classical syndromes for which vertigo is the leading symptom (e.g. positional vertigo, vestibular neuritis, Menière's disease), vertigo may occur as main or accompanying symptom of a multitude of ENT-related diseases involving the inner ear...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/29275134/comparative-safety-of-drugs-targeting-the-nitric-oxide-pathway-in-pulmonary-hypertension-a-mixed-approach-combining-a-meta-analysis-of-clinical-trials-and-a-disproportionality-analysis-from-the-who-pharmacovigilance-database
#13
C Khouri, M Lepelley, M Roustit, F Montastruc, M Humbert, J L Cracowski
BACKGROUND: Recent guidelines recommend riociguat, a soluble guanylate cyclase (sGC) stimulator, as well as the type 5 phosphodiesterase inhibitor (PDE5i) tadalafil or sildenafil as treatments for pulmonary arterial hypertension. We compared the safety profiles of sildenafil, tadalafil and riociguat in pulmonary hypertension. METHODS: We combined two approaches: First, we performed a meta-analysis of safety data extracted from randomized controlled trials. Secondly, we conducted a disproportionality analysis of data from VigiBase, the WHO global database of individual case safety reports, to compare the safety profiles with real life data...
December 21, 2017: Chest
https://www.readbyqxmd.com/read/29259575/visually-induced-dizziness-in-children-and-validation-of-the-pediatric-visually-induced-dizziness-questionnaire
#14
Marousa Pavlou, Susan L Whitney, Abdulaziz A Alkathiry, Marian Huett, Linda M Luxon, Ewa Raglan, Emma L Godfrey, Doris-Eva Bamiou
Aims: To develop and validate the Pediatric Visually Induced Dizziness Questionnaire (PVID) and quantify the presence and severity of visually induced dizziness (ViD), i.e., symptoms induced by visual motion stimuli including crowds and scrolling computer screens in children. Methods: 169 healthy (female n = 89; recruited from mainstream schools, London, UK) and 114 children with a primary migraine, concussion, or vestibular disorder diagnosis (female n = 62), aged 6-17 years, were included...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29244042/feasibility-and-effects-of-a-nursing-intervention-for-patients-with-peripheral-vestibular-disorders
#15
Carina Faag, Johan Bergenius, Christina Forsberg, Ann Langius-Eklöf
PURPOSE: To explore the feasibility and possible outcomes of a nursing intervention in patients with peripheral vestibular disorders. DESIGN: A randomized controlled trial (RCT). METHODS: Thirty-six patients participated in the study: the intervention group (n = 18), who received the intervention, and patients in a control group (n = 18), who received standard care. The intervention includes patient education and individualized nursing support during a 6-month rehabilitation period...
September 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29242950/superior-canal-dehiscence-syndrome-diagnosis-with-vestibular-evoked-myogenic-potentials-and-fremitus-nystagmus
#16
R Gürkov, C Jerin, W Flatz, R Maxwell
BACKGROUND: Superior canal dehiscence syndrome (SCDS) is a relatively rare neurotological disorder that is characterized by a heterogeneous clinical picture. Recently, vestibular evoked myogenic potential (VEMP) measurement was established for the diagnosis of SCDS. In the present study, a case series of patients with SCDS were analyzed, with a focus on VEMP. METHODS: Four patients with SCDS were prospectively examined with ocular VEMP (oVEMP) and cervical VEMP (cVEMP)...
December 14, 2017: HNO
https://www.readbyqxmd.com/read/29238670/specific-organ-targeted-vestibular-physiotherapy-the-pivot-in-the-contemporary-management-of-vertigo-and-imbalance
#17
EDITORIAL
Anirban Biswas, Bibhas Barui
Introduction: Advancements in our understanding of vestibular physiology and how it is changes in different diseases have established that of the three therapeutic approaches to treat disorders of the vestibular system viz. pharmacotherapy, surgery and physical therapy, it is the later i.e., physical therapy which is the most efficacious modality in the management of balance disorders. The futility of vestibular sedatives in the correction of vestibular disorders and in the restoration of balance and the very limited role of surgery has now been recognised...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29234822/-acute-vestibular-syndrome-clinical-examination-outperforms-mri-in-the-detection-of-central-lesions
#18
REVIEW
F Thömke
A significant number of patients who seek medical treatment in an emergency department because of vertigo or dizziness, suffer from acute vestibular syndrome. This is characterized by sustained vertigo, horizontal or horizontal rotatory jerk nystagmus, and unsteady stance and gait. In the acute situation it is crucial to differentiate patients with a peripheral vestibular disorder from those with a central disease. A number of recent studies have shown that a structured clinical examination enables a reliable differential diagnosis of central or peripheral disorders...
December 12, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29226324/tandem-walking-as-a-quick-screening-test-for-vestibular-disorders
#19
Helen S Cohen, Jasmine Stitz, Haleh Sangi-Haghpeykar, Susan P Williams, Ajitkumar P Mulavara, Brian T Peters, Jacob J Bloomberg
OBJECTIVES/HYPOTHESIS: Although many screening tests of balance are available, few of them have been well validated for clinical or research uses. The goal of this study was to test an updated version of an old test, Tandem Walking, to determine how useful it is for screening patients with vestibular disorders. STUDY DESIGN: Case-control study. METHODS: Subjects were 90 adult patients with vestibular disorders and 292 healthy adult controls...
December 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29224460/implementation-of-rocking-chair-therapy-for-veterans-in-residential-substance-use-disorder-treatment-formula-see-text
#20
Rene' L Cross, Justin White, Jaclyn Engelsher, Stephen S O'Connor
BACKGROUND: Substance use disorder (SUD) and mental health diagnosis negatively affect Veteran homelessness. OBJECTIVE: Assess the acceptance and feasibility of rocking chair therapy as a self-implemented intervention for mood and substance cravings. PICOT: For homeless Veterans in SUD treatment, how does adding vestibular stimulation by use of a rocking chair compared with treatment as usual affect levels of anxiety and substance cravings? RESULTS: Two significant findings were observed...
December 1, 2017: Journal of the American Psychiatric Nurses Association
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