Frank Jacobsen, Ramesh Pushpadevan, Florian Viehweger, Morton Freytag, Ria Schlichter, Natalia Gorbokon, Franziska Büscheck, Andreas M Luebke, Devita Putri, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Christoph Fraune, Christian Bernreuther, Patrick Lebok, Guido Sauter, Sarah Minner, Stefan Steurer, Ronald Simon, Eike Burandt, David Dum, Florian Lutz, Andreas H Marx, Till Krech, Till S Clauditz
Cadherin-17 (CDH17) is a membranous cell adhesion protein predominantly expressed in intestinal epithelial cells. CDH17 is therefore considered a possible diagnostic and therapeutic target. This study was to comprehensively determine the expression of CDH17 in cancer and to further assess the diagnostic utility of CDH17 immunohistochemistry (IHC). A tissue microarray containing 14,948 interpretable samples from 150 different tumor types and subtypes as well as 76 different normal tissue types was analyzed by IHC...
January 28, 2024: Pathology, Research and Practice