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B N Shultz, P Bovonratwet, N T Ondeck, T D Ottesen, R P McLynn, J N Grauer
BACKGROUND CONTEXT: The use of national databases in spinal surgery outcomes research is increasing. A number of variables collected by the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) changed between 2010 and 2011, coinciding with a rapid increase in the number of patients included per year. However, there has been limited study evaluating the effect that these changes may have on the results of outcomes studies. PURPOSE: To investigate the influence of changing data elements and growth of the NSQIP database on results of lumbar fusion outcomes studies...
April 9, 2018: Spine Journal: Official Journal of the North American Spine Society
Peter S Khang, Susan E Wang, In-Lu Amy Liu, Heather L Watson, Sandra Y Koyama, Dan N Huynh, Janet S Lee, Huong Q Nguyen
BACKGROUND: Additional evidence is needed regarding the impact of inpatient palliative care (IPC) on the quality of end-of-life care and downstream utilization. AIM: Examine the effects of IPC on quality of end-of-life care and acute and postacute care use in a large integrated system. DESIGN: Retrospective cohort design. SETTING/PARTICIPANTS: Adult decedents from January 1, 2012, to December 31, 2014, who had at least one hospitalization at 11 Kaiser Permanente Southern California medical centers in the 12 months before death and not hospitalized for a trauma-related condition or receiving home-based PC or hospice were included in the cohort...
March 13, 2018: Journal of Palliative Medicine
Danyang Zhou, Ying Wu, Zhenyu Lin, Liangliang Shi, Lei Zhao, Tao Liu, Dandan Yu, Tao Zhang
Aims: Gastric cancer (GC) is often diagnosed at an advanced stage; inexpensive and valid biomarkers for GC are still unavailable. We aimed to evaluate the prognosis of the combination of pretreatment red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) in patients with GC. Methods: A retrospective analysis from 103 GC patients who were diagnosed at our institution from 2012 to 2016 was performed. Both pretreatment RDW and NLR were calculated based on the recommended cutoff values of 13...
2018: Gastroenterology Research and Practice
Michal Nowak, Wieslaw Tryniszewski, Agata Sarniak, Anna Wlodarczyk, Piotr J Nowak, Dariusz Nowak
Oxidative reactions can result in the formation of electronically excited species that undergo radiative decay depending on electronic transition from the excited state to the ground state with subsequent ultra-weak photon emission (UPE). We investigated the UPE from the Fe2+ -EGTA (ethylene glycol-bis(β-aminoethyl ether)- N , N , N ', N '-tetraacetic acid)-H₂O₂ system with a multitube luminometer (Peltier-cooled photon counter, spectral range 380 to 630 nm). The UPE of 92.6 µmol/L Fe2+ -185.2 µmol/L EGTA-2...
April 10, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Nasser Sakran, Shiri Sherf-Dagan, Orit Blumenfeld, Orly Romano-Zelekha, Asnat Raziel, Dean Keren, Itamar Raz, Dan Hershko, Ian M Gralnek, Tamy Shohat, David Goitein
BACKGROUND: Although bariatric surgery (BS) is considered safe, concern remains regarding severe post-operative adverse events and mortality. Using a national BS registry, the aim of this study was to assess the incidence, etiologies, and risk factors for mortality following BS. METHODS: Prospective data from the National Registry of Bariatric Surgery in Israel (NRBS) including age, gender, BMI, comorbidities, and surgical procedure information were collected for all patients who underwent BS in Israel between June 2013 and June 2016...
April 7, 2018: Obesity Surgery
Juan Pedro Arrebola, Argelia Castaño, Marta Esteban, Mónica Bartolomé, Beatriz Pérez-Gómez, Juan José Ramos
Diet is considered the main source of Persistent Organic Pollutant (POP) exposure in the general population, although there are still several gaps of knowledge regarding the differential contribution of main food groups. The aim of this study was to identify dietary patterns that contribute to human exposure to organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and Perfluoroalkyl Substances (PFASs). Study population (n=1880, 18-65years old) was recruited during 2009-2010 in all the main geographical areas of Spain...
April 5, 2018: Science of the Total Environment
Xiao-Yu Hu, Yun Li, Long-Quan Li, Yuan Zheng, Jia-Hong Lv, Shu-Chun Huang, Weinong Zhang, Liang Liu, Ling Zhao, Zhuiguo Liu, Xiu-Ju Zhao
OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is a major public health burden in China, and its prevalence is increasing. This study aimed to determine the risk factors and biomarkers of NAFLD. DESIGN: An observational cross-sectional primary survey. SETTING: Central China. PARTICIPANTS: The study included 1479 participants aged over 18 and below 80 years, not currently being treated for cancer or infectious disease or no surgery in the previous year, and no history of cancer or an infectious disease...
April 5, 2018: BMJ Open
Carla A Mazefsky, Lan Yu, Susan W White, Matthew Siegel, Paul A Pilkonis
Individuals with autism spectrum disorder (ASD) often present with prominent emotion dysregulation that requires treatment but can be difficult to measure. The Emotion Dysregulation Inventory (EDI) was created using methods developed by the Patient-Reported Outcomes Measurement Information System (PROMIS® ) to capture observable indicators of poor emotion regulation. Caregivers of 1,755 youth with ASD completed 66 candidate EDI items, and the final 30 items were selected based on classical test theory and item response theory (IRT) analyses...
April 6, 2018: Autism Research: Official Journal of the International Society for Autism Research
Sanja Pilipović-Dragović, Aleksandar J Ristić, Zoran Bukumirić, Goran Trajković, Dragoslav Sokić
Due to a limited number of patients with drug-resistant parietal lobe epilepsy in surgical series, there are insufficient data about long-term seizure outcome following surgery restricted to the parietal lobe. We performed a meta-analysis to asses long-term outcomes in patients with parietal lobe epilepsy who underwent surgery confined to the parietal lobe or resection with major involvement of the parietal cortex. An English language literature search for studies on parietal lobe surgery and outcome was conducted using the MEDLINE database, followed by a manual search based on specific criteria...
April 6, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
Lee Joseph, Mohammad Bashir, Qun Xiang, Babatunde A Yerokun, Roland Albert Matsouaka, Sreekanth Vemulapalli, Samir Kapadia, Joaquin E Cigarroa, Firas Zahr
OBJECTIVES: This study sought to examine the prevalence of mitral stenosis (MS) and its impact on in-hospital and 1-year clinical outcomes among patients undergoing transcatheter aortic valve replacement (TAVR). BACKGROUND: Patients with coexisting severe aortic stenosis and MS are increasingly being considered for TAVR. METHODS: The study cohort included 44,755 patients (age ≥18 years) who underwent TAVR during November 1, 2011, to September 30, 2015, and were registered in Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapies (TVT) Registry...
April 9, 2018: JACC. Cardiovascular Interventions
Jamie C E Coyle, Alan J Kemp, John-Mark Hopkins, Alexander A Lagatsky
We report a broadly wavelength-tunable femtosecond diode-pumped Ti:sapphire laser, passively mode-locked using both semiconductor saturable absorber mirror (SESAM) and Kerr-lens mode-locking (KLM) techniques. Using two pump laser diodes (operating at 450 nm), an average output power as high as 433 mW is generated during mode-locking with the SESAM. A tunability range of 37 nm (788-825 nm) was achieved with the shortest pulse duration of 62 fs at 812 nm. In the KLM regime, an average output power as high as 382 mW, pulses as short as 54 fs, and a tunability of 120 nm (755-875 nm) are demonstrated...
March 19, 2018: Optics Express
Laurens J De Sadeleer, Caressa Meert, Jonas Yserbyt, Hans Slabbynck, Johny A Verschakelen, Eric K Verbeken, Birgit Weynand, Ellen De Langhe, Jan L Lenaerts, Benoit Nemery, Dirk Van Raemdonck, Geert M Verleden, Athol U Wells, Wim A Wuyts
BACKGROUND: The advice of a dynamic multidisciplinary discussion (MDD) is believed to be important in the diagnosis of interstitial lung diseases (ILD). However, to what extent MDD diagnoses differ from the preliminary diagnoses before formal work-up and MDD (preMDD diagnoses), is still insufficiently studied. METHODS: We compared preMDD and MDD diagnoses in patients discussed at the Leuven University Hospitals MDD between January 2005 and December 2015. RESULTS: Of 938 consecutive patients discussed in MDD, 755 (80...
March 30, 2018: Chest
Jessica L Buicko, Shevonne S Satahoo, Krishnamurti A Rao, Juan E Sola, Holly L Neville
PURPOSE: Ovarian and testicular torsions are emergencies requiring prompt surgical treatment to preserve gonadal function. However, diagnosis in females is often delayed owing to nonspecific symptoms. We sought to assess disparities in management and outcomes between males and females with torsion. METHODS: The National Inpatient Sample was queried for pediatric patients with "emergent", "urgent", or "trauma center" admission and ICD-9 codes for ovarian torsion and testicular torsion...
February 12, 2018: Journal of Pediatric Surgery
K El-Boghdadly, A B Docherty, A A Klein
The National Institute of Academic Anaesthesia (NIAA) was founded in 2008 to lead a UK strategy for developing academic anaesthesia. We aimed to assess the distribution of applications and quantify the academic returns of NIAA-supported research grants, as this has hitherto not been analysed. We sought data on the baseline characteristics of all grant applicants and recipients. Every grant recipient from 2008 to 2015 was contacted to ascertain the status of their supported research projects. We also examined Google Scholar, Scopus® database and InCites Journal Citation Reports for citation, author and journal metrics, respectively...
March 30, 2018: Anaesthesia
Dorothee Mielke, Vesna Malinova, Onnen Moerer, Patricia Suntheim, Martin Voit, Veit Rohde
We retrospectively compared the outcome of aneurysmal subarachnoid hemorrhage (aSAH) patients treated in a neurosurgical ICU (nICU) between 1990 and 2005 with that of patients treated in a general ICU (gICU) between 2005 and 2013 with almost identical treatment strategies. Among other parameters, we registered the initial Hunt and Hess grade, Fisher score, the incidence of vasospasm, and outcome. A multivariate analysis (logistic regression model) was performed to adjust for different variables. In total, 755 patients were included in this study with 456 patients assigned to the nICU and 299 patients to the gICU...
March 30, 2018: Neurosurgical Review
Crystal Lam, Adel Elkbuli, Brenda Benson, Elizabeth Young, Orlando Morejon, Dessy Boneva, Shaikh Hai, Mark McKenney
BACKGROUND: The development of hospital acquired pressure ulcers (HAPUs) is a common complication associated with immobilization and prolonged hospitalization in trauma patients. Our semi-annual Trauma Quality Improvement Program (TQIP) report identified HAPUs as an outlier complication. We employed a hospital-wide initiative to reduce the incidence of HAPUs among our trauma patient population. Our study aimed to determine if the implemented measures would decrease HAPUs incidence rates...
March 26, 2018: Journal of the American College of Surgeons
Peng-Cheng Duan, Dennis-Helmut Manz, Sebastian Dechert, Serhiy Demeshko, Franc Meyer
Dioxygen activation at nickel complexes is much less studied than for the biologically more relevant iron or copper systems but promises new reactivity patterns because of the distinct coordination chemistry of nickel. Here we report that a pyrazolate-based dinickel(II) dihydride complex [KL(Ni-H)2 ] (1a) smoothly reacts with O2 via reductive H2 elimination to give the μ-1,2-peroxo dinickel(II) complex [KLNi2 (O2 )] (2a) and, after treatment with dibenzo[18]-crown-6, the separated ion pair [K(DB18C6)][LNi2 (O2 )] (2b); these are the first μ-1,2-peroxo dinickel intermediates to be characterized by X-ray diffraction...
March 29, 2018: Journal of the American Chemical Society
Shuko Takahashi, Fumitaka Tanaka, Yuki Yonekura, Kozo Tanno, Masaki Ohsawa, Kiyomi Sakata, Makoto Koshiyama, Akira Okayama, Motoyuki Nakamura
BACKGROUND: Several types of cardiovascular diseases (CVDs) impair the physical and mental status. The purpose of this study was to assess the predictive ability of several cardiovascular biomarkers for identifying the incidence of disability as future recipients of public long-term care (LTC) service. METHODS: The subjects of this study were community-dwelling elderly individuals ≥ 65 years of age without a history of CVD (n = 5,755; mean age, 71 years). The endpoint of this study was official certification as a recipient of LTC...
2018: PloS One
Diana Campelo, Thomas Lautier, Philippe Urban, Francisco Esteves, Sophie Bozonnet, Gilles Truan, Michel Kranendonk
[This corrects the article on p. 755 in vol. 8, PMID: 29163152.].
2018: Frontiers in Pharmacology
Anne-Marie Makhlouf, Michel P Kossovsky, France Gurba, Sophie Pautex, Marinette Chikhi, Claude Pichard, Laurence Genton
BACKGROUND & AIMS: The severity of pain is routinely assessed in hospitalised patients but the impact of pain and pain control on energy coverage has been poorly studied. This One-day cross-sectional observational study assessed the association between severity of pain and coverage of energy needs in hospitalised patients. METHODS: Foods provided and consumed were assessed on one day by dedicated dieticians for unselected hospitalised patients receiving three meals per day...
March 17, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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