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https://www.readbyqxmd.com/read/29033583/the-effects-of-nonsteroidal-anti-inflammatory-drugs-in-the-incident-and-recurrent-risk-of-hepatocellular-carcinoma-a-meta-analysis
#1
Qing Pang, Hao Jin, Kai Qu, Zhongran Man, Yong Wang, Song Yang, Lei Zhou, Huichun Liu
BACKGROUND: Recent studies have showed that nonsteroidal anti-inflammatory drugs (NSAIDs) could reduce the risk of several types of cancer. However, epidemiological evidence of the association between NSAIDs intake and the risk of hepatocellular carcinoma (HCC) remains controversial. METHODS: To assess the preventive benefit of NSAIDs in HCC, we simultaneously searched the databases of PubMed, EmBase, Web of Science, and Scopus and screened eligible publications...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29032588/clinical-significance-of-lactate-clearance-for-the-development-of-early-allograft-dysfunction-and-short-term-prognosis-in-deceased-donor-liver-transplantation
#2
Deok Gie Kim, Jee Youn Lee, Yoon Bin Jung, Seung Hwan Song, Jae Geun Lee, Han Dai Hoon, Dong Jin Joo, Man Ki Ju, Gi Hong Choi, Jin Sub Choi, Myoung Soo Kim, Soon Il Kim
This retrospective study evaluated lactate clearance (LC), measured at 6, 12, 18, and 24 hours after reperfusion, as a predictor of early allograft dysfunction (EAD) and short-term outcomes in patients receiving deceased donor liver transplantation. Of 181 transplant recipients, 44 (24.3%) developed EAD and had lower LCs than those who did not develop EAD. A receiver operating characteristic analysis showed that LC determined at 6 hours showed the highest area under curve value of 0.828 (95% confidence interval [CI]: 0...
October 15, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29026745/psychometric-properties-of-the-trust-in-physician-scale-in-tamil-nadu-india
#3
Maria Jusler Kalsingh, Geetha Veliah, Vijayaprasad Gopichandran
CONTEXT: Trust in health care is of high intrinsic value. It also leads to positive outcomes such as better treatment adherence and disclosure of sensitive information. Therefore, there is a need to measure trust in health care objectively. AIMS: To assess the psychometric properties of the Trust in Physician Scale in Tamil Nadu, India. SETTINGS AND DESIGN: The study was conducted in a private tertiary hospital setting in Tamil Nadu by a cross-sectional survey design...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29025891/impact-and-associations-of-eosinophilic-inflammation-in-copd-analysis-of-the-aeris-cohort
#4
Viktoriya L Kim, Ngaire A Coombs, Karl J Staples, Kristoffer K Ostridge, Nicholas P Williams, Stephen A Wootton, Jeanne-Marie Devaster, Emmanuel Aris, Stuart C Clarke, Andrew C Tuck, Simon C Bourne, Tom M A Wilkinson
Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) predicts response to treatment, especially corticosteroids. We studied the nature of eosinophilic inflammation in COPD prospectively to examine the stability of this phenotype and its dynamics across exacerbations, and its associations with clinical phenotype, exacerbations and infection.127 patients aged 40-85 years with moderate to very severe COPD underwent repeated blood and sputum sampling at stable visits and within 72 h of exacerbation for 1 year...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29023500/the-ghosts-of-hela-how-cell-line-misidentification-contaminates-the-scientific-literature
#5
Serge P J M Horbach, Willem Halffman
While problems with cell line misidentification have been known for decades, an unknown number of published papers remains in circulation reporting on the wrong cells without warning or correction. Here we attempt to make a conservative estimate of this 'contaminated' literature. We found 32,755 articles reporting on research with misidentified cells, in turn cited by an estimated half a million other papers. The contamination of the literature is not decreasing over time and is anything but restricted to countries in the periphery of global science...
2017: PloS One
https://www.readbyqxmd.com/read/29020484/long-term-outcome-of-a-patient-with-paradoxical-hypertrichosis-after-laser-epilation
#6
Adam Honeybrook, Tascha Crossing, Eric Bernstein, Jason Bloom, Julie Woodward
One underreported, rare side effect of laser hair removal, is paradoxical hypertrichosis. It is largely unknown what the long-term outcomes are of patients who develop this complication. We report a 21-year-old, Fitzpatrick II, male patient, who had patchy areas of dark hair affecting various body areas. An Alexandrite 755 nm laser was used to address the desired areas at energies between 20-22 J/cm(2) at 10-12 week intervals over a course of 7 treatments. After 3 treatments, the patient noted a significant increase in the density and length of hairs involving the back, shoulders, neck and upper arms...
October 11, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29016541/a-novel-treatment-of-acne-keloidalis-nuchae-by-long-pulsed-alexandrite-laser
#7
Abeer Tawfik, Mai Abdelraouf Osman, Iman Rashwan
BACKGROUND: Acne keloidalis nuchae (AKN) is a dermatological condition characterized by follicular-based papules and pustules that later form hypertrophic or keloid-like scars. Laser-assisted hair reduction such as 810-nm diode laser and 1,064-nm Nd:YAG laser have been used for treating AKN with promising results. OBJECTIVE: To evaluate the therapeutic effect and safety of alexandrite laser in the treatment of different lesions of AKN. METHODS: Seventeen male patients with AKN received 6 sessions of 755-nm alexandrite laser...
October 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28992017/digestible-metabolizable-and-net-energy-of-camelina-cake-fed-to-growing-pigs-and-additivity-of-energy-in-mixed-diets
#8
J W Kim, B Koo, C M Nyachoti
This experiment was conducted to determine the DE, ME, and NE contents of camelina cake (CC) and to test the hypothesis that dietary glucosinolates originating from CC will affect the additivity of energy in mixed diets containing different inclusion levels of corn, soybean meal (SBM), and CC. A total of 30 growing barrows ([Yorkshire × Landrace] × Duroc) with a mean BW of 16.8 kg (SD 1.4) were randomly allotted to 1 of 5 treatments with 6 replicates per treatment. Pigs were fed experimental diets for 16 d, including 10 d for adaptation and 6 d for total collection of feces and urine...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28989283/abdominal-pain-and-nausea-in-the-diagnosis-of-streptococcal-pharyngitis-in-boys
#9
Hiroshi Igarashi, Naoki Nago, Hiromichi Kiyokawa, Motoharu Fukushi
OBJECTIVES: This study was designed to assess the accuracy of gastrointestinal symptoms, including abdominal pain, nausea, and vomiting, in the diagnosis of Group A streptococcal (GAS) pharyngitis in children and to determine differences in diagnostic accuracy in boys versus girls. METHODS: This retrospective cross-sectional study included 5,755 consecutive patients aged <15 years with fever in the electronic database at a primary care practice. Gastrointestinal symptoms were recorded in the database according to the International Classification of Primary Care codes, and the data were extracted electronically...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28986410/thrombolysis-in-acute-ischemic-stroke-in-patients-with-dementia-a-swedish-registry-study
#10
Eva Zupanic, Mia von Euler, Ingemar Kåreholt, Beatriz Contreras Escamez, Johan Fastbom, Bo Norrving, Dorota Religa, Milica G Kramberger, Bengt Winblad, Kristina Johnell, Maria Eriksdotter, Sara Garcia-Ptacek
OBJECTIVE: To compare access to intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) and its outcomes in patients with and without dementia. METHODS: This was a longitudinal cohort study of the Swedish dementia and stroke registries. Patients with preexisting dementia who had AIS from 2010 to 2014 (n = 1,356) were compared with matched patients without dementia (n = 6,755). We examined access to thrombolysis and its outcomes at 3 months (death, residency, and modified Rankin Scale [mRS] score)...
October 6, 2017: Neurology
https://www.readbyqxmd.com/read/28984539/the-importance-of-extent-of-choroid-plexus-cauterization-in-addition-to-endoscopic-third-ventriculostomy-for-infantile-hydrocephalus-a-retrospective-north-american-observational-study-using-propensity-score-adjusted-analysis
#11
Aria Fallah, Alexander G Weil, Kyle Juraschka, George M Ibrahim, Anthony C Wang, Louis Crevier, Chi-Hong Tseng, Abhaya V Kulkarni, John Ragheb, Sanjiv Bhatia
OBJECTIVE Combined endoscopic third ventriculostomy (ETC) and choroid plexus cauterization (CPC)-ETV/CPC- is being investigated to increase the rate of shunt independence in infants with hydrocephalus. The degree of CPC necessary to achieve improved rates of shunt independence is currently unknown. METHODS Using data from a single-center, retrospective, observational cohort study involving patients who underwent ETV/CPC for treatment of infantile hydrocephalus, comparative statistical analyses were performed to detect a difference in need for subsequent CSF diversion procedure in patients undergoing partial CPC (describes unilateral CPC or bilateral CPC that only extended from the foramen of Monro [FM] to the atrium on one side) or subtotal CPC (describes CPC extending from the FM to the posterior temporal horn bilaterally) using a rigid neuroendoscope...
October 6, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28982107/risk-factor-for-vital-signs-fluctuation-during-colonoscopy-under-conscious-sedation-consisting-of-midazolam-and-meperidine
#12
Shigeo Banno, Motohiko Kato, Yukie Sunata, Yuichiro Hirai, Yoko Kubosawa, Keiichiro Abe, Yoshiaki Takada, Tetsu Hirata, Yusaku Takatori, Michiko Wada, Satoshi Kinoshita, Hideki Mori, Kaoru Takabayashi, Masahiro Kikuchi, Toshio Uraoka
BACKGROUND: Sedatives or analgesics are widely used to relieve a patient's discomfort during colonoscopy (CS). Although cardiopulmonary adverse events are sometimes experienced during the examination, the risk factors for vital signs fluctuation (VSF) have not been fully elucidated. This study thus aimed to identify the risk factors for VSF during the examination, as well as to evaluate the frequency and the degree of VSF. SUMMARY: A total of 755 consecutive subjects who received CS under endoscopist-administrated sedation using midazolam, meperidine, or combination of both were retrospectively analyzed...
October 6, 2017: Digestive Diseases
https://www.readbyqxmd.com/read/28977766/tobacco-smoke-incursions-and-satisfaction-among-residents-with-children-in-multiunit-housing-united-states-2013
#13
Karen M Wilson, Michelle R Torok, Robert C McMillen, Jonathan D Klein, Douglas E Levy, Jonathan P Winickoff
OBJECTIVES: Residents of multiunit housing can be exposed to tobacco smoke even if they do not permit smoking in their homes. Although even low levels of tobacco smoke exposure can cause health problems for children and adults, some landlords are reluctant to ban smoking for fear of decreased occupancy rates or tenant satisfaction. The objective of this study was to assess the impact of tobacco smoke-free policies and tobacco-smoke incursions on housing satisfaction in multiunit housing residences with children...
January 1, 2017: Public Health Reports
https://www.readbyqxmd.com/read/28977298/anthropometry-and-clustered-cardiometabolic-risk-factors-in-young-people-a-systematic-review
#14
Teresa Maria Bianchini de Quadros, Alex Pinheiro Gordia, Luciana Rodrigues Silva
OBJECTIVE: To conduct a systematic review of the literature on the ability of anthropometric indicators to predict clustered cardiometabolic risk factors (CMRF) in children and adolescents. DATA SOURCE: Studies published from June 1st, 2011 to May 31st, 2016 in the PubMed, SciELO and LILACS databases were analyzed. The research was based on keywords derived from the terms "anthropometric indicators" AND "cardiometabolic risk factors". Observational studies on the ability of anthropometric indicators as predictors of clustered CMRF in children and adolescents in Portuguese, English and Spanish languages were included...
July 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28963740/the-prognostic-significance-of-incomplete-revascularization-and-untreated-coronary-anatomy-following-percutaneous-coronary-intervention-an-analysis-of-6-755-patients-with-multivessel-disease
#15
M Bilal Iqbal, Robert D Smith, Rebecca Lane, Niket Patel, Wala Mattar, Tito Kabir, Vasileios Panoulas, Mark Mason, Miles C Dalby, Richard Grocott-Mason, Charles D Ilsley
BACKGROUND: More than half of the patients undergoing percutaneous coronary intervention (PCI) have multivessel disease. Whether complete revascularization impacts long-term mortality or whether selected patients or those with specific coronary anatomy benefit from complete revascularization is unclear. METHODS: A total of 14,452 patients underwent PCI between 2004 and 2015 at Harefield Hospital, UK. Of these, 7,076 patients had multivessel disease. We excluded 321 patients with left main-stem stenosis ≥50%, with 6,755 patients included in the analysis (936 patients had complete revascularization)...
September 30, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28957253/highly-efficient-mirrorless-optical-parametric-oscillator-pumped-by-nanosecond-pulses
#16
Charlotte Liljestrand, Andrius Zukauskas, Valdas Pasiskevicius, Carlota Canalias
A highly efficient mirrorless optical parametric oscillator (MOPO), pumped by narrowband nanosecond pulses at 1064 nm, is demonstrated. The MOPO is based on quasi-phase-matched parametric interaction of counter-propagating photons in 1-mm-thick periodically poled Rb-doped KTiOPO4 crystal with a period of 755 nm. It generates a co-propagating signal at 1740 nm and a counter-propagating idler at 2741 nm, achieving mJ-level output with a total signal-and-idler conversion efficiency of 47%. Both generated waves present narrow spectral bandwidths, thanks to the unique properties of the counter-propagating nonlinear interaction...
July 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28955301/out-of-reference-range-thyroid-stimulating-hormone-levels-in-levothyroxine-treated-primary-hypothyroid-patients-a-multicenter-observational-study
#17
Dilek Gogas Yavuz, Dilek Yazıcı, Lezzan Keskin, Ayşegül Atmaca, Seda Sancak, Fulden Saraç, İbrahim Şahin, Oğuz Dikbaş, Zeliha Hekimsoy, Serap Yalın, Melin Uygur, Murat Yılmaz, Sibel Yirmibeşcik, Özlem Asmaz
OBJECTIVE: Although levothyroxine (LT4) replacement therapy for hypothyroidism has been established as safe, inexpensive and effective, many studies from different countries reported out-of-reference range thyroid-stimulating hormone (TSH) values for the hypothyroid patients under LT4 treatment. The aim of this study was to determine TSH levels of primary hypothyroid patients under LT4 treatment and to assess self-reported compliance with daily LT4 intake in tertiary care centers in Turkey...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28954446/-effect-of-blood-pressure-control-level-on-perinatal-outcomes-in-women-with-mild-moderate-gestational-hypertension
#18
Y Shen, Z Yang, Y Chen, Y Y Shi
Objective: To investigate the effect of blood pressure (BP) control level on perinatal outcomes in women with mild-moderate gestational hypertension (GHp). Methods: Totally, 344 women diagnosed initially as mild-moderate GHp who delivered in Peking University Third Hospital from January 2012 to December 2016 were recruited. They were divided into four groups according to the stabilized level of BP during pregnancy. (1) Group A: BP<130/80 mmHg (1 mmHg=0.133 kPa) ; (2) Group B: BP (130-139) / (80-89) mmHg; (3) Group C: BP (140-149) / (90-99) mmHg; (4) Group D: BP (150-159) / (100-109) mmHg...
September 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28954332/-clinical-effect-of-vacuum-sealing-drainage-in-the-treatment-of-complex-fracture-and-dislocation-of-foot-with-severe-soft-tissue-injury
#19
H D Ma, Y Gao, S G Li, J Bai, X J Du, H D Liu, J J Li, W D Liang, L H Cao, J F Qu
Objective: To observe the clinical effect of vacuum sealing drainage (VSD) in the treatment of complex fracture and dislocation of foot with severe soft tissue injury. Methods: From March 2012 to January 2015, a retrospective analysis of 108 cases of the foot closed complex fracture dislocation with severe soft tissue injury in Department of Foot and Ankle, the Second Hospital of Tangshan City, Tangshan.Injury mechanisms included press and crush injury, traffic accident.According to the operation the cases were divided into the VSD group (56 cases) and the control group (52 cases)...
September 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28947988/association-analysis-of-apo-gene-polymorphisms-with-ischemic-stroke-risk-a-case-control-study-in-a-chinese-han-population
#20
Rongjun Xiao, Shuaiqi Sun, Jiayi Zhang, Yongri Ouyang, Ning Zhang, Min Yang, Tianbo Jin, Ying Xia
This study aimed to assess the association of APO gene polymorphisms and ischemic stroke risk in a Chinese Han population. In this case-control study, we genotyped 14 single nucleotide polymorphisms (SNPs) in 3 APO genes in 488 cases and 503 controls using Sequenom Mass-ARRAY technology and evaluated their association with ischemic stroke using the χ2 and genetic model analysis. In the allelic model analysis, we determined three SNPs were significantly associated with ischemic stroke: rs693 with a p value of 0...
September 1, 2017: Oncotarget
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