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https://www.readbyqxmd.com/read/29449396/draft-genome-sequence-of-a-pathogenic-vibrio-vulnificus-strain-isolated-in-brazil
#1
Monique Ribeiro Tiba-Casas, Eneida Gonçalves Lemes-Marques, Elisabete Aparecida Almeida, Flávia Barrosa Soares, Carlos Henrique Camargo
We describe the draft genome sequence of the clinical Vibrio vulnificus strain 03_7315, isolated in 2016 from the blood of a diabetic patient who died of septicemia after ingestion of seafood. The draft genome, with 4,755,588 bp covering two chromosomes, presented 4,434 genes, 4,213 coding sequences, and 117 pseudogenes.
February 15, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29449338/status-of-hypertension-in-china-results-from-the-china-hypertension-survey-2012-2015
#2
Zengwu Wang, Zuo Chen, Linfeng Zhang, Xin Wang, Guang Hao, Zugui Zhang, Lan Shao, Ye Tian, Ying Dong, Congyi Zheng, Jiali Wang, Manlu Zhu, William S Weintraub, Runlin Gao
Background -Although the prevalence of hypertension (HTN) continues to increase in developing countries including China, recent data are lacking. A national wide survey was conducted from October 2012 to December 2015 to assess the prevalence of HTN in China. Methods -A stratified multistage random sampling method was used to obtain a nationally representative sample of 451,755 residents aged ≥18 years from 31 provinces in mainland China from October 2012 to December 2015. Blood pressure (BP) was measured after resting for 5 minutes by trained staff, using a validated oscillometric BP monitor...
February 15, 2018: Circulation
https://www.readbyqxmd.com/read/29443795/posterior-precortical-vitreous-pockets-in-high-myopia-observed-by-enhanced-vitreous-imaging-of-spectral-domain-optical-coherence-tomography
#3
Xiaohan Wang, Mengxi Shen, Ruoshi Wang, Yanping Zhou, Tong Li, Meichun Xiao, Minlu Song, Xiaodong Sun, Fenghua Wang
PURPOSE: To observe the vitreous in highly myopic eyes with posterior precortical vitreous pockets (PPVPs) using enhanced vitreous imaging of spectral domain optical coherence tomography. METHODS: Fifty-two highly myopic eyes with PPVPs of 36 patients were included in this study. All subjects underwent enhanced vitreous imaging optical coherence tomography. The size of PPVPs was measured, and the frequency of imaging features was recorded. RESULTS: Nine imaging features of the vitreous in highly myopic eyes with PPVPs were found...
February 13, 2018: Retina
https://www.readbyqxmd.com/read/29441441/comparison-of-practice-guidelines-brcapro-and-genetic-counselor-estimates-to-identify-germline-brca1-and-brca2-mutations-in-pancreatic-cancer
#4
Robert C Grant, Spring Holter, Ayelet Borgida, Neesha C Dhani, David W Hedley, Jennifer J Knox, Mohammad R Akbari, George Zogopoulos, Steven Gallinger
Germline BRCA1 and BRCA2 (BRCA) mutation carriers with pancreatic ductal adenocarcinoma (PDAC) may benefit from precision therapies and their relatives should undergo tailored cancer prevention. In this study, we compared strategies to identify BRCA carriers with PDAC. Incident cases of PDAC were prospectively recruited for BRCA sequencing. Probands were evaluated using the National Comprehensive Cancer Network (NCCN) and the Ontario Ministry of Health and Long-Term Care (MOHLTC) guidelines. The probability of each proband carrying a mutation was estimated by surveying genetic counselors and using BRCAPRO...
February 13, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29434986/association-between-clinicopathological-factors-and-postoperative-radiotherapy-in-patients-with-completely-resected-pathological-n2-non-small-cell-lung-cancer
#5
Yujin Xu, Jianqiang Li, Jin Wang, Xiao Hu, Honglian Ma, Pu Li, Xiao Zheng, Ming Chen
The function of postoperative radiotherapy (PORT) in patients with completely resected pathologically N2 (pN2) non-small cell lung cancer (NSCLC) remains controversial due to a lack of prospective studies. The present study aimed to evaluate the efficacy of PORT in completely resected pN2 NSCLC when using modern radiation techniques, and to determine the associations between clinicopathological factors and PORT and survival rates. Following patient selection, 246 out of 269 consecutive patients with pN2 NSCLC were enrolled in the present study, with 88 patients having received postoperative chemotherapy (POCT) and PORT, 90 having received adjuvant chemotherapy, 1 having received adjuvant radiotherapy and the remaining 67 having received no adjuvant therapy...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29432267/effectiveness-of-preoperative-antibiotics-in-preventing-surgical-site-infection-after-common-soft-tissue-procedures-of-the-hand
#6
Kevin Li, Tanmaya D Sambare, Sam Y Jiang, Emily J Shearer, Nathan P Douglass, Robin N Kamal
BACKGROUND: Antibiotic prophylaxis is a common but controversial practice for clean soft tissue procedures of the hand, such as carpal tunnel release or trigger finger release. Previous studies report no substantial reduction in the risk of surgical site infection (SSI) after antibiotic prophylaxis, yet are limited in power by low sample sizes and low overall rates of postoperative infection. QUESTIONS/PURPOSES: Is there evidence that antibiotic prophylaxis decreases the risk of SSI after soft tissue hand surgery when using propensity score matching to control for potential confounding variables such as demographics, procedure type, medication use, existing comorbidities, and postoperative events? METHODS: This retrospective analysis used the Truven Health MarketScan databases, large, multistate commercial insurance claims databases corresponding to inpatient and outpatient services and outpatient drug claims made between January 2007 and December 2014...
February 8, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29430077/hypoxia-inducible-factor-1%C3%AE-in-antarctic-notothenioids-contains-a-polyglutamine-and-glutamic-acid-insert-that-varies-in-length-with-phylogeny
#7
A S Rix, T J Grove, K M O'Brien
The long evolution of the Antarctic perciform suborder of Notothenioidei in the icy, oxygen-rich waters of the Southern Ocean may have reduced selective pressure to maintain a hypoxic response. To test this hypothesis, cDNA of the key transcriptional regulator of hypoxic genes, hypoxia-inducible factor-1α (HIF-1α), was sequenced in heart ventricles of the red-blooded notothenioid, Notothenia coriiceps, and the hemoglobinless icefish, Chaenocephalus aceratus. HIF-1α cDNA is 4500 base pairs (bp) long and encodes 755 amino acids in N...
December 2017: Polar Biology
https://www.readbyqxmd.com/read/29428250/does-seed-migration-increase-the-risk-of-second-malignancies-in-prostate-cancer-patients-treated-with-iodine-125-loose-seeds-brachytherapy
#8
Eric Vigneault, Kevin Martell, Daniel Taussky, Siraj Husain, Guila Delouya, Khaly Mbodji, Julie Piotte, Sindy Magnan, Philippe Després, Marie-Claude Lavallée, Sylviane Aubin, Luc Beaulieu, William Foster, André-Guy Martin
PURPOSE: To evaluate the risk of second malignancies after migration of seeds (MS) in prostate cancer patients treated with 125 I loose seeds brachytherapy. METHODS AND MATERIALS: Data from 2802 prostate cancer patients treated with 125 I loose seeds brachytherapy in 3 Canadian centers were reviewed. After seeds implant, all patients underwent postimplant pelvic radiography and computed tomography scan for postimplant dosimetry. These images were used to assess whether seed migration occurred...
December 28, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29426783/reduced-frontal-activity-during-a-verbal-fluency-test-in-fibromyalgia-a-near-infrared-spectroscopy-study
#9
Po-Han Chou, Kuo-Tung Tang, Yi-Hsing Chen, Chia-Wei Sun, Chih-Mao Huang, Der-Yuan Chen
Fibromyalgia (FM) is a complex disorder characterized by widespread chronic pain and associated sleep problems and cognitive dysfunction. However, only few studies focusing on cognitive dysfunction in FM are available so far. In the present study, we aimed to use near infrared spectroscopy (NIRS) to evaluate the brain function in FM patients subjected to a verbal fluency test (VFT). A total of 11 primary FM patients and 13 healthy individuals (HC) underwent NIRS while performing a VFT. The Fibromyalgia Impact Questionnaire (FIQ) was used to evaluate the symptom severity of FM and Beck Depression Inventory II (BDI) was used to evaluate the severities depression symptoms in study participants...
February 6, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29425827/association-of-hla-dpb1-polymorphisms-with-rheumatoid-arthritis-a-systemic-review-and-meta-analysis
#10
REVIEW
Lu Jiang, Dongdong Jiang, Yao Han, Xian Shi, Changle Ren
BACKGROUND: The current reports on the association between HLA-DPB1 alleles and rheumatoid arthritis (RA) results were controversial. Thus, we conducted a meta-analysis to assess whether DPB1 alleles are associated with increased risk of rheumatoid arthritis. METHODS: Systematic searches on PubMed, Embase, Elsevier, CNKI (China National Knowledge Infrastructure), Wanfang data and Cochrane Library prior to July 2017 were performed. The pooled odds ratios (ORs) and 95% confidence interval (95% CI) was used to assess the association between frequencies of DPB1 alleles and RA patients...
February 6, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29423841/treatment-of-flat-and-elevated-pigmented-disorders-with-a-755-nm-alexandrite-picosecond-laser-clinical-and-histological-evaluation
#11
Adrian Alegre-Sanchez, Natalia Jiménez-Gómez, Óscar M Moreno-Arrones, Pablo Fonda-Pascual, Bibiana Pérez-García, Pedro Jaén-Olasolo, Pablo Boixeda
The novel picosecond lasers, initially developed for faster tattoo removal, have also shown great efficacy in endogenous pigmentary disorders. To describe the efficacy and safety profile of an alexandrite (755-nm) picosecond laser in a wide range of pigmented flat and elevated cutaneous lesions. A retrospective study was performed in which we collected all the clinical images of patients treated with the 755-nm alexandrite picosecond laser for 12 months (November 2016-November 2017). Clinical features were obtained from their medical charts...
February 9, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29417206/depressive-residual-symptoms-are-associated-with-illness-course-characteristics-in-a-sample-of-outpatients-with-bipolar-disorder
#12
Gianluca Serafini, Gustavo H Vazquez, Xenia Gonda, Maurizio Pompili, Zoltan Rihmer, Mario Amore
Rates of 50-70% of residual symptoms referring to subsyndromal manifestations between episodes that do not meet the required criteria for episode definition were reported in bipolar disorder (BD). However, the specific role of these symptoms on the course of BD patients is poorly understood; thus, we aimed to investigate factors associated with depressive residual symptoms. Overall, 255 currently euthymic BD outpatients on maintenance treatment, including 95 (37.2%) males and 160 (62.8%) females, were consecutively recruited at the Section of Psychiatry, Department of Neuroscience, University of Genoa (Italy) and underwent detailed structured interviews, comprehensive clinical interviews, and clinical record reviews for assessment/collection of relevant information concerning the course of illness and clinical status including cross-referral of all available information...
February 7, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29416604/cunr-scoring-system-for-the-prediction-of-lateral-lymph-node-metastasis-in-papillary-thyroid-carcinoma
#13
Jianyong Lei, Gengpeng Li, Zhihui Li, R X Rong, Jingqiang Zhu
Objective: Our present study aimed to evaluate and compare the number and rate of central lymph node metastases (LNMs) for the prediction of lateral LNM (LLNM) in papillary thyroid carcinoma (PTC) and to develop a scoring system. Results: Capsule invasion, tumor location in the upper portion of the thyroid, an ipsilateral central compartment LNM number ≥3, and an ipsilateral central compartment LNM rate of ≥56% were identified as significant independent predictors of ipsilateral lateral LNM in PTC...
January 2, 2018: Oncotarget
https://www.readbyqxmd.com/read/29409142/baseline-retinal-examinations-among-sle-patients-newly-initiating-hydroxychloroquine-in-a-u-s-medicaid-sle-population-2000-2010
#14
Tzu-Chieh Lin, Michael F Marmor, Medha Barbhaiya, Hongshu Guan, Sarah K Chen, Candace H Feldman, Karen H Costenbader
OBJECTIVES: Baseline retinal examination has long been recommended at hydroxychloroquine (HCQ) initiation, but it is unknown how well this guideline is followed. We investigated baseline eye examinations among U.S. Medicaid SLE patients initiating HCQ. METHODS: Using billing codes, we identified SLE patients aged 18-65 enrolled in Medicaid, residing in the 29 most populated U.S. states from 2000-2010. New HCQ users were identified by filling a prescription, with none in the preceding 12 months...
February 6, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29408739/planned-home-versus-planned-hospital-births-in-women-at-low-risk-pregnancy-a-systematic-review-with-meta-analysis
#15
REVIEW
A Cristina Rossi, Federico Prefumo
New interest in home birth have recently arisen in women at low risk pregnancy. Maternal and neonatal morbidity of women planning delivery at home has yet to be comprehensively quantified. We aimed to quantify pregnancy outcomes following planned home (PHB) versus planned hospital birth (PHos). We did a systematic review of maternal and neonatal morbidity following planned home (PHB) versus planned hospital birth (PHos). We included prospective, retrospective, cohort and case-control studies of low risk pregnancy outcomes according to planning place of birth, identified from January 2000 to June 2017...
January 29, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29408275/a-novel-c2-screw-trajectory-preliminary-anatomical-feasibility-and-biomechanical-comparison
#16
NingNing Dou, Jennifer N Lehrman, Anna G U S Newcomb, Brian P Kelly
BACKGROUND: Pedicle screw and translaminar screw fixation in C2 may not be applicable in many patients with anatomical abnormalities or narrow laminar thickness and spinous process height. The objective of the current study was to assess the morphometric and mechanical feasibilities of a novel alternate C2 screw trajectory. METHODS: A novel screw trajectory that pierces the bifid base of C2 is described. Anatomical measures that determine the feasibility of spinous process bifid base (SPB) screw fixation were assessed in 14 cadaver C2 vertebrae...
February 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29402727/salivary-glycopatterns-as-potential-biomarkers-for-screening-of-early-stage-breast-cancer
#17
Xiawei Liu, Hanjie Yu, Yan Qiao, Jiajun Yang, Jian Shu, Jiaxu Zhang, Zhiwei Zhang, Jianjun He, Zheng Li
OBJECTIVE: We systematically investigated and assessed the alterations of salivary glycopatterns and possibility as biomarkers for diagnosis of early-stage breast cancer. DESIGN: Alterations of salivary glycopatterns were probed using lectin microarrays and blotting analysis from 337 patients with breast benign cyst or tumor (BB) or breast cancer (I/II stage) and 110 healthy humans. Their diagnostic models were constructed by a logistic stepwise regression in the retrospective cohort...
February 2, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29400882/optical-properties-of-spatially-dispersive-dielectric-spheres-erratum
#18
R Ruppin
Corrections are given for typographical errors in J. Opt. Soc. Am.71, 755 (1981)JOSAAH0030-394110.1364/JOSA.71.000755.
February 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29399777/investigation-of-the-effect-of-equivac%C3%A2-hev-hendra-virus-vaccination-on-thoroughbred-racing-performance
#19
K Schemann, E J Annand, P A Reid, M F Lenz, P C Thomson, N K Dhand
OBJECTIVE: To evaluate the effect of Equivac® HeV Hendra virus vaccine on Thoroughbred racing performance. DESIGN: Retrospective pre-post intervention study. METHODS: Thoroughbreds with at least one start at one of six major south-eastern Queensland race tracks between 1 July 2012 and 31 December 2016 and with starts in the 3-month periods before and after Hendra virus vaccinations were identified. Piecewise linear mixed models compared the trends in 'Timeform rating' and 'margin to winner' before and after initial Hendra virus vaccination...
February 4, 2018: Australian Veterinary Journal
https://www.readbyqxmd.com/read/29395257/assessing-health-related-quality-of-life-in-primary-sj%C3%A3-gren-s-syndrome-the-pss-qol
#20
Angelika Lackner, Martin H Stradner, Josef Hermann, Julia Unger, Tanja Stamm, Winfried B Graninger, Christian Dejaco
OBJECTIVES: To develop a questionnaire for the assessment of health-related quality of life (HRQL) in primary Sjögren's syndrome (PSS), and to test its psychometric properties. METHODS: Based on the concepts of a previous qualitative study, a questionnaire for the assessment of HRQL in PSS (PSS-QoL) was developed. Psychometric testing of PSS-QoL was performed after revising the first draft with feedback of patients (n = 6) and clinicians (n = 4). Convergent construct validity was assessed by correlating the score with the EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI), EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) and Euro-QoL 5D (EQ-5D)...
November 27, 2017: Seminars in Arthritis and Rheumatism
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