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G M Thomas, A Minassian, X Sheng, M J Damzen
We present the first study of Q-switched Alexandrite lasers under continuous-wave diode-pumping with operation up to 10 kHz repetition rates in TEM<sub>00</sub>, with spatial quality M<sup>2</sup> 1.15. With a pulsed-diode dual-end-pumped design, pulse energy is scaled to a record level of 3 mJ. We also demonstrate, for the first time, cavity-dumped Q-switching of diode-pumped Alexandrite lasers under continuous-wave and pulsed diode-pumping, up to 10 kHz. Pulse energy of 510 μJ is demonstrated with 3 ns pulse duration and 170 kW peak power, in TEM<sub>00</sub> with M<sup>2</sup> < 1...
November 28, 2016: Optics Express
K J Ahn, B J Kim, S B Cho
BACKGROUND: Laser therapy is the treatment of choice in tattoo removal. However, the precise mechanisms of laser-tattoo pigment interactions remain to be evaluated. METHODS: We evaluated the geometric patterns of laser-tattoo pigment particle interactions using a tattoo pigment-embedded tissue-mimicking (TM) phantom. RESULTS: A Q-switched (QS) neodymium-doped yttrium aluminum garnet laser was used at settings of 532-, 660-, and 1064-nm wavelengths, single-pulse and quick pulse-to-pulse treatment modes, and spot sizes of 4 and 7 mm...
November 20, 2016: Skin Research and Technology
Pelin Üstüner, Ali Balevi, Mustafa Özdemir
INTRODUCTION: There is no satisfactory and efficient method for long-term removal of white-colored and thin hair. METHODS: We conducted a randomised clinical trial of hirsute patients with excessive white and/or thin hair on the face and/or axilla. In Group I (n: 16), the facial hair on one side of the face was painted with a black eyelash mascara immediately before Nd:YAG laser and the other half was only treated by Nd:YAG. In Group II (n: 20), the axillary hair on one side was painted with the mascara before the Alexandrite laser with the other side being only treated by Alexandrite...
October 20, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Sang Hyung Lee, Mi-Hye Lee, Tai-Kyung Noh, Kwang-Ho Choi, Chong-Hyun Won, Sung Eun Chang, Mi-Woo Lee, Jee-Ho Choi
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
Hyun-Min Seo, Jung-In Kim, Han-Saem Kim, Young-Jun Choi, Won-Serk Kim
BACKGROUND: Rosacea treatments including oral/topical medications and laser therapy are numerous but unsatisfactory. OBJECTIVE: To compare the effectiveness of the dual wavelength long-pulsed 755-nm alexandrite/1,064-nm neodymium: yttrium-aluminum-garnet laser (LPAN) with that of 585-nm pulsed dye laser (PDL) for rosacea. METHODS: This was a randomized, single-blinded, comparative study. Full face received four consecutive monthly treatments with LPAN or PDL, followed-up for 6 months after the last treatment...
October 2016: Annals of Dermatology
Takafumi Ohshiro, Toshio Ohshiro, Katsumi Sasaki, Kazuo Kishi
Background and aims: Recently novel picosecond duration lasers (ps-lasers) have been developed for the treatment of multicolored and recalcitrant tattoos, and safety and efficacy have been reported. We therefore hypothesized that the ps-laser could be an alternative treatment for dermal pigmented lesions and performed a retrospective review to evaluate the efficacy and safety of the ps-laser. Subjects and methods: A retrospective photographic review of 10 patients with dermal pigmented lesions was performed (ages from 4 months to 52 yr), 6 nevus of Ota, 3 ectopic Mongolian spots and 1 Mongolian spots...
June 29, 2016: Laser Therapy
Robert A Weiss, David H McDaniel, Margaret A Weiss, Anne Marie Mahoney, Karen L Beasley, Christian R Halvorson
INTRODUCTION: Picosecond lasers have been reported to be effective for removal of tattoo pigment. This prospective study evaluated the efficacy and safety of the treatment of peri-oral and -ocular wrinkles using a novel diffractive lens array coupled with a picosecond 755 nm alexandrite laser. METHODS: Forty female subjects presenting with wrinkles from photodamage were enrolled in an IRB approved study. Subjects received four picosecond diffractive lens array treatments to the full face at 1 month intervals...
September 29, 2016: Lasers in Surgery and Medicine
Robabeh Alijanpour, Fatemeh Aliakbarpour
BACKGROUND AND OBJECTIVES: Hirsutism or excess hair growth is a common dermatological problem in females, affecting up to 10% of females worldwide. We aimed this study to compare the two hair-shortening methods shaving vs. snipping among hirsute women regarding the outcome of the therapy and also the paradoxical hypertrichosis phenomenon (terminal hair regrowth) 6 months after the final therapy session. MATERIALS AND METHODS: In this study, 129 premenopausal women affected by hirsutism were randomly divided into two study groups according to hair-shortening method: shaving as group A (66 patients) and hair shortening by scissor as group B (63 patients)...
September 11, 2016: Journal of Cosmetic Dermatology
Aurélie Lorgeou, Christine Chiaverini, Florence Le Duff, Jean-Philippe Lacour, Thierry Passeron
Angiokeratoma is a benign vascular ectasia that involves the papillary dermis. The least common variant of angiokeratoma is angiokeratoma circumscriptum naeviforme(ACN) which is clinically characterized by dark red to blue black, hyperkeratotic papules, nodules or plaques occurring frequently unilaterally on a lower extremity. The lesions show no tendency for spontaneous remission and the treatment is challenging. Surgery or C02 laser can be proposed but they are difficult to perform in large lesions and they induce visible scarring...
August 11, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Hannah John, Nikolaos Manoloudakis, J Stephen Sinclair
AIM: To conduct a systematic review of the effectiveness of various types of lasers (and light based therapies) for the treatment of hidradenitis suppurativa (HS) and to establish recommendations based on our findings. DATA SOURCES: MEDLINE, Cochrane and PubMed databases. STUDY SELECTION: English language studies describing the use of laser for the treatment of HS. DATA EXTRACTION: Multiple reviewers performed independent extraction and identified 22 studies that met the inclusion and exclusion criteria...
October 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Min Kyung Lee, Kyung Sik Min, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
BACKGROUND: Long-pulsed, 755-nm, alexandrite lasers have been shown to be effective and safe in the treatment of pigmentary lesions. OBJECTIVE: Clinical outcomes and side effects in the treatment of melasma using a fractional, long-pulsed, alexandrite laser were assessed. MATERIALS AND METHODS: Forty-eight patients with melasma received 2 to 4 treatment sessions of fractional, long-pulsed, alexandrite laser at 2 to 3 weeks intervals. The parameter of treatment was 60 to 80 J/cm without dynamic cooling device using 15-mm spot size of fractional hand piece, with a 0...
August 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
E Grillo, P González-Muñoz, P Boixeda, A Cuevas, S Vañó, P Jaén
BACKGROUND: Port wine stains (PWSs) are commonly treated by the pulsed dye laser. However, treatment of hypertrophic or resistant PWSs is a major therapeutic challenge. The long-pulsed Alexandrite laser could be a safe and effective treatment for resistant PWSs, due to an increase depth of penetration of 50-75% over PDL. OBJECTIVE: The aim of this study was to assess the efficacy and safety of a long-pulsed Alexandrite laser in patients with hypertrophic, dark and/or resistant PWSs...
September 2016: Actas Dermo-sifiliográficas
Shirin Ghanbari, Reza Akbari, Arkady Major
The generation of 170 fs pulses at 755 nm from a Kerr-lens mode-locked Alexandrite laser was demonstrated. The laser was pumped at 532 nm and produced 780 mW of average output power with 9.8% of optical-to-optical efficiency. To the best of our knowledge, these are the shortest pulses that have been produced from a mode-locked Alexandrite laser to date.
June 27, 2016: Optics Express
Ichiro Kasajima
The gemstone alexandrite is known for its feature to change color depending on the spectral quality of the incident light. Thus, the stone looks green when illuminated by white LED light but looks red when illuminated by incandescent light. This effect (alexandrite effect) is caused by a special relationship between the spectral quality of the incident light and the absorbance spectrum of the stone. Here we report an alexandrite-like effect in the petals of torenia and cyclamen flowers. These flowers are purple in sunlight but magenta (reddish) in incandescent light, and violet (bluish purple) in white LED light...
2016: Scientific Reports
Muhammed Nurullah Bulut, Ümit Çallı, Eren Göktaş, Kezban Bulut, Baran Kandemir, Yusuf Özertürk
Alexandrite laser is one of the most common methods of hair removal. Its utilization is gradually increasing due to easy accessibility and high effectiveness. However, the disuse of protective goggles during the application of this laser is a serious problem. In this case report, we presented a 35-year-old male patient who had foveal injury by alexandrite laser. The inflammatory process secondary to the foveal injury and subsequent macular edema were treated with Ozurdex because of its potent antiedematous effect...
January 2016: Case Reports in Ophthalmology
Emil A Tanghetti
BACKGROUND AND OBJECTIVES: The treatment of acne scars and wrinkles with a picosecond Alexandrite laser was recently FDA cleared. In 2014 we presented our initial histologic findings with this device on in vivo and ex vivo skin. This current study expands on the 2014 pilot study with an investigation of different energy settings using histology and the confocal microscope to describe the changes observed in the skin. MATERIALS AND METHODS: We used a 755 nm picosecond Alexandrite laser with a fractional optic with three different energy settings to treat in vivo...
September 2016: Lasers in Surgery and Medicine
Berit C Carlsen, Emily Wenande, Andres M Erlendsson, Annesofie Faurschou, Christine Dierickx, Merete Haedersdal
BACKGROUND AND OBJECTIVES: Pulsed dye laser (PDL) represents the gold-standard treatment for port wine stains (PWS). However, approximately 20% of patients are poor responders and yield unsatisfactory end-results. The Alexandrite (Alex) laser may be a therapeutic alternative for selected PWS subgroups, but optimal laser parameters are not known. The aim of this study was to assess clinical PWS clearance and safety of Alex laser at a range of pulse durations. MATERIALS AND METHODS: Sixteen individuals (14 previously PDL-treated) with deep red (n = 4), purple macular (n = 5) and purple hypertrophic (n = 7) PWS were included...
April 28, 2016: Lasers in Surgery and Medicine
Douglas C Wu, Richard E Fitzpatrick
BACKGROUND AND OBJECTIVES: Multi-modal combination treatments for facial rejuvenation offer the potential to achieve superior results in a single treatment session. In this study, we evaluate the safety and efficacy of combining multiple laser modalities in a single treatment session. METHODS: Fifty patients underwent a multi-modal facial laser resurfacing procedure consisting of the sequential use of 595 nm pulsed dye laser, 755 nm alexandrite laser, superficial fractionated and fully ablative CO2 laser, superficial fully ablative erbium-YAG laser, and deep fractionated ablative CO2 laser in a single treatment session...
August 2016: Lasers in Surgery and Medicine
John Kozub, Jin H Shen, Karen M Joos, Ratna Prasad, M Shane Hutson
BACKGROUND AND OBJECTIVE: Optic nerve sheath fenestration is an established procedure for relief of potentially damaging overpressure on the optic nerve resulting from idiopathic intracranial hypertension. Prior work showed that a mid-IR free-electron laser could be delivered endoscopically and used to produce an effective fenestration. This study evaluates the efficacy of fenestration using a table-top mid-IR source based on a Raman-shifted alexandrite (RSA) laser. STUDY DESIGN/MATERIALS AND METHODS: Porcine optic nerves were ablated using light from an RSA laser at wavelengths of 6...
March 2016: Lasers in Surgery and Medicine
Muhammad Adil Abbas Khan, Ammar Asrar Javed, Karthikeyan Srinivasan Govindan, Sadia Rafiq, Kay Thomas, Lynne Baker, John Kenealy
Pilonidal sinus (PNS) and its surgical management have a profound impact on hospital resources in terms of finances and productive man-hours. Surgical treatment has been the mainstay of treatment of both acute and chronic pilonidal sinus but recurrence is common. The control of hair growth in the sinus region plays an important role in preventing recurrence. Here, we discuss our experience of treating 19 patients suffering from recurrent pilonidal sinus with laser depilation and its long-term cost effectiveness...
July 2016: Lasers in Medical Science
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