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https://www.readbyqxmd.com/read/28325021/evaluation-of-lung-ventilation-distribution-in-chronic-obstructive-pulmonary-disease-patients-using-the-global-inhomogeneity-index
#1
F Trenk, L Mendes, P Carvalho, R P Paiva, J Henriques, N Maglaveras, I Chouvarda, V Tsara, C A Teixeira
The global inhomogeneity (GI) index is a electrical impedance tomography (EIT) parameter that quantifies the tidal volume distribution within the lung. In this work the global inhomogeneity index was computed for twenty subjects in order to evaluate his potential use in the detection and follow up of chronic obstructive pulmonary disease (COPD) patients. EIT data of 17 subjects were acquired: 14 patients with the main diagnoses of COPD and 3 healthy subjects which served as a control group. Two or three datasets of around 30 seconds were acquired at 33 scans/s and analysed for each subject...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28325004/study-of-phase-estimation-methods-to-analyse-cardiorespiratory-synchronization-in-osa-patients
#2
Jordi Sola-Soler, Beatriz F Giraldo, Jose A Fiz, Raimon Jane
Obstructive Sleep Apnea (OSA) is a sleep disorder highly prevalent in the general population. Cardiorespiratory Phase Synchronization (CRPS) is a form of non-linear interaction between respiratory and cardiovascular systems that was found to be reduced in severe OSA patients. The Hilbert Transform (HT) method was the recommended choice for estimating the respiratory phase in CRPS studies. But we have noticed that HT provides a phase that is aligned to the transition between the exhalation and the inhalation parts of different breathing cycles, instead of being aligned to the breathing onsets...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324994/co-activation-periods-of-gastrocnemius-and-vastus-lateralis-during-walking-evaluated-by-surface-electromyography
#3
Alessandro Mengarelli, Annachiara Strazza, Agnese Sbrollini, Angela Agostinelli, Laura Burattini, Sandro Fioretti, Francesco Di Nardo
"In vivo" studies reported that the co-activation of gastrocnemius and quadriceps femoris (QF) muscles produces ACL strain values greater than those caused by an isolated activation of either muscle. Aim of this study was to assess the co-activation of gastrocnemius (lateral head, GL) and vastus lateralis (VL) in healthy and young adults during walking. To this purpose the Statistical Gait Analysis was performed, that allows a characterization of gait considering hundreds of strides belonging to the same walking trial...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324975/quantification-of-peripheral-and-central-blood-pressure-variability-using-a-time-frequency-method
#4
Z Kouchaki, M Butlin, A Qasem, A P Avolio
Systolic blood pressure variability (BPV) is associated with cardiovascular events. As the beat-to-beat variation of blood pressure is due to interaction of several cardiovascular control systems operating with different response times, assessment of BPV by spectral analysis using the continuous measurement of arterial pressure in the finger is used to differentiate the contribution of these systems in regulating blood pressure. However, as baroreceptors are centrally located, this study considered applying a continuous aortic pressure signal estimated noninvasively from finger pressure for assessment of systolic BPV by a time-frequency method using Short Time Fourier Transform (STFT)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324959/a-robotic-exoskeleton-to-treat-crouch-gait-from-cerebral-palsy-initial-kinematic-and-neuromuscular-evaluation
#5
Zachary F Lerner, Diane L Damiano, Thomas C Bulea
A robotic exoskeleton was designed for individuals with crouch gait caused by cerebral palsy with the intent to supplement existing muscle function during walking. The aim of this study was to evaluate how powered knee extension assistance provided during stance and swing phases of the gait cycle affect knee kinematics, and knee flexor and extensor muscle activity. Muscle activity and kinematic data were collected from four individuals with crouch gait from cerebral palsy during their normal walking condition and while walking with the exoskeleton under stance, swing, and stance & swing assistance...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324958/ultrafast-oscillatory-flow-pcr-for-amplication-of-urine-short-tandem-repeats
#6
Haoyu Tang, Tao Dong
The short tandem repeats (STRs) in human urine which is the most sensitive body fluid can be serviced as biomarkers for the individual identification. PCR microchips are automated, sensitive and rapid. In this report, COMSOL with Finite Element Analysis (FEA) is employed to study the temperature distribution of the base layer to optimize the structure of the microfluidic chip. Meanwhile, the oscillatory PCR microdevice is preliminary tested by DNA samples extracted from urine with the FTA papers and CSF1PO, TPOX, TH01 Multiplex kits...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324949/muscle-synergy-analysis-in-transtibial-amputee-during-ramp-ascending-activity
#7
P Mehryar, M S Shourijeh, H F Maqbool, M Torabi, A A Dehghani-Sanij
In developed countries, the highest number of amputees are elderly with transtibial amputation. Walking on inclined surfaces is difficult for amputees due to loss of muscle volume and strength thereby transtibial amputees (TA) rely on the intact limb to maintain stability. The aim of this study was to use the concatenated non-negative matrix factorization (CNMF) technique to calculate muscle synergy components and compare the difference in muscle synergies and their associated activation profiles in the healthy and amputee groups during ramp ascending (RA) activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324920/an-open-label-randomized-parallel-phase-ii-trial-to-evaluate-the-efficacy-and-safety-of-a-cremophor-free-polymeric-micelle-formulation-of-paclitaxel-as-first-line-treatment-for-ovarian-cancer-a-korean-gynecologic-oncology-group-study-kgog-3021
#8
Shin-Wha Lee, Yong-Man Kim, Chi Heum Cho, Young Tae Kim, Seok Mo Kim, Soo Young Hur, Jae-Hoon Kim, Byoung-Gie Kim, Seung-Cheol Kim, Hee-Sug Ryu, Soon Beom Kang
Purpose: Genexol-PM is a biodegradable cremophor EL-free polymeric micelle formulation of paclitaxel. Here we compared efficacy and safety of Genexol-PM plus carboplatin vs. Genexol plus carboplatin for ovarian cancer treatment. Materials and Methods: In this multicenter, randomized, phase II study, patients with FIGO IC-IV epithelial ovarian cancer were randomly assigned (1:1) to receive Genexol-PM 260 mg/m2 or Genexol 175 mg/m2 with 5 AUC carboplatin every three weeks (6 cycles)...
March 21, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28324898/breathing-and-swallowing-the-next-frontier
#9
Roxann Diez Gross, Marybeth Trapani-Hanasewych
The anatomical overlap of the pathways for air passage and nutrition necessitate precise coordination between the two vital functions. Neuroanatomic structures in the brainstem for sucking, breathing, and swallowing are also in close proximity and must swiftly coordinate the processes. In a healthy neonate, the oropharyngeal experience and stimulation of early feeding enables respiratory control during suckling to develop. Despite wide variability among the methods used to investigate breathing and swallowing coordination in infancy, a consistent finding of postswallow exhalation has been reported...
April 2017: Seminars in Speech and Language
https://www.readbyqxmd.com/read/28324862/heterogeneity-in-predictive-power-of-early-childhood-nutritional-indicators-for-mid-childhood-outcomes-evidence-from-vietnam
#10
Le Thuc Duc, Jere R Behrman
We utilize longitudinal data on nearly 1800 children in Vietnam to study the predictive power of alternative measures of early childhood undernutrition for outcomes at age eight years: weight-for-age (WAZ8), height-for-age (HAZ8), and education (reading, math and receptive vocabulary). We apply two-stage procedures to derive unpredicted weight gain and height growth in the first year of life. Our estimates show that a standard deviation (SD) increase in birth weight is associated with an increase of 0.14 (standard error [SE]: 0...
March 11, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28324854/accounting-for-urban-biogenic-fluxes-in-regional-carbon-budgets
#11
Brady S Hardiman, Jonathan A Wang, Lucy R Hutyra, Conor K Gately, Jackie M Getson, Mark A Friedl
Many ecosystem models incorrectly treat urban areas as devoid of vegetation and biogenic carbon (C) fluxes. We sought to improve estimates of urban biomass and biogenic C fluxes using existing, nationally available data products. We characterized biogenic influence on urban C cycling throughout Massachusetts, USA using an ecosystem model that integrates improved representation of urban vegetation, growing conditions associated with urban heat island (UHI), and altered urban phenology. Boston's biomass density is 1/4 that of rural forests, however 87% of Massachusetts' urban landscape is vegetated...
March 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28324846/novel-alk5-inhibitor-tp0427736-reduces-tgf-%C3%AE-%C3%A3-induced-growth-inhibition-in-human-outer-root-sheath-cells-and-elongates-anagen-phase-in-mouse-hair-follicles
#12
Takumi Naruse, Mari Aoki, Natsuko Fujimoto, Seiji Arase, Hajimu Oura, Yasuji Ueda, Akiko Ikeda
BACKGROUND: Androgenic alopecia (AGA) occurs as a result of the contraction of the anagen phase because of the action of androgens on hair follicles. TGF-β production from dermal papillae is enhanced by androgens, and growth inhibition of hair-follicle cells is induced by TGF-β, and the hair cycle progresses from the anagen phase to the catagen phase. We investigated both the in vitro and in vivo potency of the newly identified ALK5 inhibitor TP0427736 {6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole}...
January 25, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28324758/dynamics-of-complex-valued-fractional-order-neural-networks
#13
Eva Kaslik, Ileana Rodica Rădulescu
The dynamics of complex-valued fractional-order neuronal networks are investigated, focusing on stability, instability and Hopf bifurcations. Sufficient conditions for the asymptotic stability and instability of a steady state of the network are derived, based on the complex system parameters and the fractional order of the system, considering simplified neuronal connectivity structures (hub and ring). In some specific cases, it is possible to identify the critical values of the fractional order for which Hopf bifurcations may occur...
March 6, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28324744/centrosomes-piddosome-joins-the-counting-game
#14
Susana Godinho
Centrosome numbers are tightly regulated during the cell cycle. A new study shows that the PIDDosome prevents the propagation of cells carrying amplified centrosomes via p53 stabilisation and p21-mediated cell-cycle arrest, thus ensuring the maintenance of normal centrosome numbers.
March 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28324740/evolution-fruit-fly-clocks-on-the-edge
#15
Charalambos P Kyriacou
Fruit flies evolved in tropical regions under stable light-dark cycles. However, their photosensitive circadian clock had to adapt to extreme seasonal photoperiods during their colonisation of temperate regions. This was achieved by changing the neuronal expression of two key clock-related components.
March 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28324727/lithium-vanadate-nanowires-reduced-graphene-oxide-nanocomposites-on-titanium-foil-with-super-high-capacities-for-lithium-ion-batteries
#16
Yunhe Cao, Danyang Chai, Zhiping Luo, Ming Jiang, Weilin Xu, Chuanxi Xiong, Shan Li, Hui Liu, Dong Fang
With a theoretically high capacity and suitable discharge/charge plateaus, lithium vanadates (such as Li0.04V2O5) can be used as cathode material for lithium ion batteries. Herein, Li0.04V2O5 nanowires are densely anchored onto reduced graphene oxide (rGO) nanosheets to form a Li0.04V2O5@rGO nanocomposite by a hydrothermal method with subsequent thermal treatment. Due to this unique structure, the Li0.04V2O5@rGO exhibits remarkable rate performance and excellent cycling stability. Specifically, it delivers a reversible discharge capacity of 738...
March 2, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28324726/facile-synthesis-of-hierarchical-mesoporous-weirds-like-morphological-mno2-thin-films-on-carbon-cloth-for-high-performance-supercapacitor-application
#17
Pragati A Shinde, Vaibhav C Lokhande, Taeksoo Ji, Chandrakant D Lokhande
The mesoporous nanostructured metal oxides have a lot of capabilities to upsurge the energy storing capacity of the supercapacitor. In present work, different nanostructured morphologies of MnO2 have been successfully fabricated on flexible carbon cloth by simple but capable hydrothermal method at different deposition temperatures. The deposition temperature has strong influence on reaction kinetics, which subsequently alters the morphology and electrochemical performance. Among different nanostructured MnO2 thin films, the mesoporous weirds composed thin film obtained at temperature of 453K exhibits excellent physical and electrochemical features for supercapacitor application...
March 3, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28324725/tailoring-a-compact-and-stable-langmuir-bi-dimensional-pbx-based-layered-perovskite-film-at-the-air-water-interface-and-on-solid-support
#18
Luisa Ariza-Carmona, Gonzalo García-Espejo, María T Martín-Romero, Luis Camacho
The present work studies the stability of Langmuir organic-inorganic superlattice materials thin films consisting of layered perovskite-based films with controlled 2D framework as well as to design experimental conditions for increasing the efficiency of the organic-inorganic perovskite motif by mechanical stimulus. Therefore, a whole covering of the air/water interface by a compact and stable lead-based layered perovskite structure is pursued. A 2D layered perovskite-type hybrid structure of the form [(CH3(CH2)19NH3)2(PbX4)], X=Cl, and Br, in which, two-dimensional sheets stabilized by a inner bilayer of organic monoammonium cation matrix, is mechanically tailored by successive compression-expansion cycles...
March 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28324721/ultradispersed-nanoarchitecture-of-sns-nanoparticles-reduced-graphene-oxide-for-enhanced-sodium-storage-performance
#19
Junming Li, Xingxing Zhao, Zhian Zhang
SnSanodes for Na-ions (NIBs) batteries are known for theirs significantly high theoretical capacities involving conversion reactions and alloying/dealloying mechanisms. However, the large volume expansion of the SnS materials during electrode reactions and the lowelectrical conductivity could cause severe structural degradation and electrodes pulverization, consequently resulting in capacity fading. In this study, Ultradispersed nanoarchitecture of SnS nanoparticles/reduced graphene oxide (SnS/rGO) is prepared by the in situ growing SnS nanoparticles on the graphene followed by the thermal treatment...
March 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28324703/arousal-amplifies-biased-competition-between-high-and-low-priority-memories-more-in-women-than-in-men-the-role-of-elevated-noradrenergic-activity
#20
David Clewett, Michiko Sakaki, Ringo Huang, Shawn E Nielsen, Mara Mather
Recent findings indicate that emotional arousal can enhance memory consolidation of goal-relevant stimuli while impairing it for irrelevant stimuli. According to one recent model, these goal-dependent memory tradeoffs are driven by arousal-induced release of norepinephrine (NE), which amplifies neural gain in target sensory and memory processing brain regions. Past work also shows that ovarian hormones modulate activity in the same regions thought to support NE's effects on memory, such as the amygdala, suggesting that men and women may be differentially susceptible to arousal's dual effects on episodic memory...
February 24, 2017: Psychoneuroendocrinology
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