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https://www.readbyqxmd.com/read/28328511/wireless-power-transfer-strategies-for-implantable-bioelectronics-methodological-review
#1
Kush Agarwal, Rangarajan Jegadeesan, Yong-Xin Guo, Nitish V Thakor
Neural implants have emerged over the last decade as highly effective solutions for the treatment of dysfunctions and disorders of the nervous system. These implants establish a direct, often bidirectional, interface to the nervous system, both sensing neural signals and providing therapeutic treatments. As a result of the technological progress and successful clinical demonstrations, completely implantable solutions have become a reality and are now commercially available for the treatment of various functional disorders...
March 16, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28327889/hemodynamic-changes-after-unilateral-revascularization-for-moyamoya-disease-serial-assessment-by-quantitative-magnetic-resonance-angiography
#2
Tackeun Kim, Jae Seung Bang, O-Ki Kwon, Gyojun Hwang, Jeong Eun Kim, Hyun-Seung Kang, Won-Sang Cho, Cheolkyu Jung, Chang Wan Oh
BACKGROUND: Ultrasonic flow meters and quantitative magnetic resonance angiography quantitatively assess flow during hemodynamic evaluation of cerebral ischemia. Although their reliability and reproducibility have been verified, their clinical impact in moyamoya disease has rarely been reported. OBJECTIVE: To investigate flow measurement outcomes in moyamoya disease patients pre- and postoperatively through a retrospective observational study. METHODS: We evaluated 41 patients undergoing their first revascularization surgery who were followed ≥6 mo...
January 2, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28327777/predicting-and-assessing-rupture-in-protein-gels-under-oscillatory-shear
#3
Brice Saint-Michel, Thomas Gibaud, Sébastien Manneville
Soft materials may break irreversibly upon applying sufficiently large shear oscillations, a process whose physical mechanism remains largely elusive. In this work, the rupture of protein gels made of sodium caseinate under an oscillatory stress is shown to occur in an abrupt, brittle-like manner. Upon increasing the stress amplitude, the build-up of harmonic modes in the strain response can be rescaled for all gel concentrations. This rescaling yields an empirical criterion to predict the rupture point way before the samples are significantly damaged...
March 22, 2017: Soft Matter
https://www.readbyqxmd.com/read/28327652/a-facile-ultrasonic-assisted-fabrication-of-nitrogen-doped-carbon-dots-biobr-up-conversion-nanocomposites-for-visible-light-photocatalytic-enhancements
#4
Yifan Zhang, Mira Park, Hak Yong Kim, Bin Ding, Soo-Jin Park
A highly efficient novel photocatalyst consisting of nitrogen-carbon dots (N-CDs) and three-dimensional (3D) hierarchical BiOBr was synthesized via a simple ultrasonic-assisted method and used for the degradation of hazardous dyes. Deposition of N-CDs onto the surface of BiOBr was confirmed through structure and composition characterizations. The N-CDs/BiOBr composites exhibited superior activity for organic contaminant degradation under visible light and the 1 wt% N-CDs/BiOBr composite showed the highest degradation rate, indicating that N-CDs/BiOBr composites have great potential for application in mitigating hazardous contaminants...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327108/impact-of-the-ultrasonic-scalpel-on-the-amount-of-drained-lymph-after-axillary-or-inguinal-lymphadenectomy
#5
Olivier Gié, Marie-Laure Matthey-Gié, Pedro-Manuel Marques-Vidal, Nicolas Demartines, Maurice Matter
BACKGROUND: Seroma formation and lymphoedema are frequently encountered complications after radical lymph node dissection (RLND). Attempts to reduce the lymphatic morbidity include the use of Ultrasonic Scalpel. The aim of the present analysis was to assess the impact of the ultrasonic scalpel on the amount of drained lymph after lymph node dissection. METHODS: Patients listed for a RLND or completion lymph node dissection (CLND) were enrolled in a prospective randomized trial to compare the impact of two surgical dissection techniques (USS versus control) on the amount of drained lymph...
March 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28324933/an-ultrasonically-powered-implantable-device-for-targeted-drug-delivery
#6
Jayant Charthad, Spyridon Baltsavias, Devleena Samanta, Ting Chia Chang, Marcus J Weber, Niloufar Hosseini-Nassab, Richard N Zare, Amin Arbabian
A wirelessly powered implantable device is proposed for fully programmable and localized drug delivery. The implant is powered using an external ultrasonic transmitter and operates at <; 5% of the FDA diagnostic ultrasound intensity limit. Drug release is achieved through electrical stimulation of drug-loaded polypyrrole nanoparticles. A design methodology for the implant electronics is presented and experimentally demonstrated to be accurate in predicting the concentration of the released drug. To the best of our knowledge, this is the first ultrasonically powered implantable device platform for targeted drug delivery using electroresponsive polymers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324778/measurement-of-weld-penetration-depths-in-thin-structures-using-transmission-coefficients-of-laser-generated-lamb-waves-and-neural-network
#7
Lei Yang, I Charles Ume
The Laser/EMAT ultrasonic (LEU) technique has shown the capability to measure weld penetration depths in thick structures based on ray-tracing of laser-generated bulk and surface waves. The ray-tracing method is not applicable to laser-generated Lamb waves when the LEU technique is used to measure weld penetration depths in thin structures. In this work, transmission coefficients of Lamb waves present in the LEU signals are investigated against varying weld penetration depths. An artificial neural network is developed to use transmission coefficients of sensitive Lamb waves and LEU signal energy to predict weld penetration depths accurately...
February 28, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324777/a-feasibility-study-of-a-novel-spectral-method-using-radiofrequency-ultrasound-data-for-monitoring-laser-tissue-ablation
#8
Enrico Vannacci, Simona Granchi, Luca Breschi, Elena Biagi
This paper presents preliminary results of a new non-invasive ultrasound monitoring method called TUV (Thermotherapy Ultrasonic View) able to investigate structural tissue modifications caused by minimally invasive percutaneous laser ablation. The method, based on the spectral analysis of the raw ultrasound radiofrequency signal, develops spectral parameters in a multidimensional space and its N dimensions are represented by the central frequencies of the sub bands the signal spectrum is decomposed into. Signal processing has been performed on the data related to 7 laser treatments performed on 4 samples of removed prostatic glands which underwent laser ablation at power of 3W, 4W and 5W and energy of 1800J...
March 6, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324776/microstructural-evolution-of-ti6al4v-in-ultrasonically-assisted-cutting-numerical-modelling-and-experimental-analysis
#9
Wei Bai, Ronglei Sun, Jürgen Leopold, Vadim V Silberschmidt
This paper aims to elucidate the effect of ultrasonically assisted cutting (UAC) on microstructure in a machined surface and a chip of Ti6Al4V alloy. To investigate microstructural evolution, a FE-based cutting model with an enhanced material formulation and temperature dependent material properties was developed. A Johnson-Mehl-Avrami-Kolmogorov (JMAK) model for the Ti6Al4V alloy was employed to simulate dynamic recrystallization and predict a resultant grain size. Due to a specific thermomechanical load in UAC, the distributions of strains, strain rates and temperatures in a workpiece in the machining process were investigated...
March 9, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324775/investigation-of-the-ultrasonic-attenuation-in-anisotropic-weld-materials-with-finite-element-modeling-and-grain-scale-material-description
#10
P E Lhuillier, B Chassignole, M Oudaa, S O Kerhervé, F Rupin, T Fouquet
A finite element modeling approach of ultrasonic propagation combined with a description of the microstructure at the scale of the grains has been implemented. The simulations seek to determine the contribution of scattering to the ultrasonic attenuation in polycrystalline materials. The approach is applied to anisotropic microstructures exhibiting both elongated grains and transversely isotropic crystallographic texture which can be found in multipass welds. The ultrasonic propagation is computed with the 2D finite element code ATHENA 2D...
March 8, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324109/sex-specific-life-course-changes-in-the-neuro-metabolic-phenotype-of-glut3-null-heterozygous-mice-ketogenic-diet-ameliorates-electroencephalographic-seizures-and-improves-sociability
#11
Yun Dai, Yuanzi Zhao, Masatoshi Tomi, Bo-Chul Shin, Shanthie Thamotharan, Andrey Mazarati, Raman Sankar, Elizabeth A Wang, Carlos Cepeda, Michael S Levine, Jingjing Zhang, Andrew Frew, Jeffry R Alger, Peter Clark, Monica Sondhi, Sudatip Kositamongkol, Leah Leibovitch, Sherin U Devaskar
We tested the hypothesis that exposure of glut3+/- mice to a ketogenic diet ameliorates autism-like features which includes aberrant behavior and electrographic seizures. We first investigated the life course sex-specific changes in basal plasma-CSF-brain metabolic profile, brain glucose transport/uptake, glucose and monocarboxylate transporter proteins, and ATP in the presence or absence of systemic insulin administration. Glut3+/- male but not female mice (5m of age) displayed reduced CSF glucose/lactate concentrations with no change in brain Glut1, Mct2, glucose uptake or ATP...
January 24, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323094/denatured-protein-coated-docetaxel-nanoparticles-alterable-drug-state-and-cytosolic-delivery
#12
Li Zhang, Qingqing Xiao, Yiran Wang, Chenshuang Zhang, Wei He, Lifang Yin
Many lead compounds have a low solubility in water, which substantially hinders their clinical application. Nanosuspensions have been considered a promising strategy for the delivery of water-insoluble drugs. Here, denatured soy protein isolate (SPI)-coated docetaxel nanosuspensions (DTX-NS) were developed using an anti-solvent precipitation-ultrasonication method to improve the water-solubility of DTX, thus improving its intracellular delivery. DTX-NS, with a diameter of 150 to 250nm and drug-loading up to 18...
March 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28320891/the-normal-ranges-of-cardiovascular-parameters-measured-using-the-ultrasonic-cardiac-output-monitor
#13
Giles N Cattermole, P Y Mia Leung, Grace Y L Ho, Peach W S Lau, Cangel P Y Chan, Stewart S W Chan, Brendan E Smith, Colin A Graham, Timothy H Rainer
The ultrasonic cardiac output monitor (USCOM) is a noninvasive transcutaneous continuous wave Doppler method for assessing hemodynamics. There are no published reference ranges for normal values in adults (aged 18-60 years) for this device. This study aimed to (1) measure cardiovascular indices using USCOM in healthy adults aged 18-60 years; (2) combine these data with those for healthy children (aged 0-12), adolescents (aged 12-18), and the elderly (aged over 60) from our previously published studies in order to present normal ranges for all ages, and (3) establish normal ranges of USCOM-derived variables according to both weight and age...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28320660/experimental-validation-of-a-fast-forward-model-for-guided-wave-tomography-of-pipe-elbows
#14
Alexander J Brath, Francesco Simonetti, Peter B Nagy, Geir Instanes
Ultrasonic guided wave tomography (GWT) methods for the detection of corrosion and erosion damage in straight pipe sections are now well advanced. However, successful application of GWT to pipe bends has not yet been demonstrated due to the computational burden associated with the complex forward model required to simulate guided wave propagation through the bend. In a previous paper [Brath et al., IEEE Trans. Ultrason. Ferroelectr. Freq. Contr., vol. 61, pp. 815-829, 2014] we have shown that the speed of the forward model can be increased by replacing the three-dimensional pipe bend with a two-dimensional rectangular domain in which guided wave propagation is formulated based on an artificially inhomogeneous and elliptically anisotropic (INELAN) acoustic model...
March 15, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28320659/guided-wave-tomography-of-pipe-bends
#15
Alexander J Brath, Francesco Simonetti, Peter Nagy, Geir Instanes
Detection and monitoring of corrosion and erosion damage in pipe bends are open challenges due to the curvature of the elbow, the complex morphology of these defects, and their unpredictable location. Combining model-based inversion with guided ultrasonic waves propagating along the elbow and inside its walls, offers the possibility of mapping wall-thickness losses over the entire bend and from a few permanently installed transducers under the realm of guided wave tomography (GWT). This paper provides the experimental demonstration of GWT of pipe bends based on a novel curved ray tomography algorithm and an optimal transducer configuration consisting of two ring arrays mounted at the ends of the elbow and a line of transducers fixed to the outer side of the elbow (extrados)...
March 15, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28320656/targeting-effects-on-the-volume-of-the-focused-ultrasound-induced-blood-brain-barrier-opening-in-non-human-primates-in-vivo
#16
Maria Eleni Karakatsani, Gesthimani Samiotaki, Matthew Downs, Vincent Ferrera, Elisa Konofagou
Drug delivery to subcortical regions is susceptible to the blood-brain barrier (BBB) impeding the molecular exchange between the blood stream and the brain parenchyma. Focused ultrasound coupled with the administration of microbubbles has been proven to open the BBB locally, transiently and non-invasively both in rodents and in Non-Human-Primates (NHPs). The development of this disruption technique independent of MRI monitoring is of primordial importance yet restrained to the targeting optimization. The current paper establishes the linear relationship of the incidence angle with the volume of BBB opening (VBBB) and the Peak Negative Pressure (PNP) when sonicating the Caudate Nucleus and the Putamen region of five non-human-primates...
March 13, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28319821/application-of-p4-polyphase-codes-pulse-compression-method-to-air-coupled-ultrasonic-testing-systems
#17
Honggang Li, Zhenggan Zhou
Air-coupled ultrasonic testing systems are usually restricted by low signal-to-noise ratios (SNR). The use of pulse compression techniques based on P4 Polyphase codes can improve the ultrasound SNR. This type of codes can generate higher Peak Side Lobe (PSL) ratio and lower noise of compressed signal. This paper proposes the use of P4 Polyphase sequences to code ultrasound with a NDT system based on air-coupled piezoelectric transducer. Furthermore, the principle of selecting parameters of P4 Polyphase sequence for obtaining optimal pulse compression effect is also studied...
March 3, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28319820/evidence-of-a-broadband-gap-in-a-phononic-crystal-strip
#18
Etienne Coffy, Sébastien Euphrasie, Mahmoud Addouche, Pascal Vairac, Abdelkrim Khelif
We experimentally demonstrate a very large ultrasonic band gap in a one-dimensional phononic crystal. The structure consists of periodic tungsten pillars fixed to a tailored silicon strip with a layer of epoxy. Combining local resonances and Bragg scattering, the gap ranges from 450kHz to 1250kHz, which corresponds to a gap-to-midgap ratio of 94%, and the attenuation exceeds 35dB with only three periods. Numerical calculations with the Finite Element Method are performed to support the analysis and provide a better understanding of the behavior of the structure...
March 6, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28318963/an-investigation-of-ultrasound-effect-on-digestate-solubilization-and-methane-yield
#19
Temesgen Garoma, David Pappaterra
In this study, different ultrasound power intensities of 0.05-0.21kW/L (4.13-16.52kWh/kg TS) were applied at a frequency of 20kHz and for durations of 5-20min to digestate obtained from a domestic wastewater treatment plant. The ultrasonic effect on digestate solubilization was revealed by increased levels of soluble Chemical Oxygen Demand (sCOD), soluble Total Organic Carbon (sTOC), and soluble Total Nitrogen (sTN) released into the solution. The highest material release was achieved at an ultrasonic energy intensity of 0...
March 16, 2017: Waste Management
https://www.readbyqxmd.com/read/28318889/non-invasive-liver-ablation-using-histotripsy-preclinical-safety-study-in-an-in%C3%A2-vivo-porcine-model
#20
Eli Vlaisavljevich, Gabe Owens, Jonathan Lundt, Dejan Teofilovic, Kimberly Ives, Alexander Duryea, Jim Bertolina, Theodore H Welling, Zhen Xu
This study investigates the safety profile for use of histotripsy, a non-invasive ultrasonic ablation method currently being developed for the treatment of liver cancer, for liver ablation in an in vivo porcine model. Histotripsy treatments were applied to the liver and hepatic veins of 22 porcine subjects, with half of the subjects receiving systemic heparinization. Vital signs (heart rate, blood pressure, temperature, electrocardiogram and SpO2) were monitored throughout the procedure and for 1 h post-treatment...
March 16, 2017: Ultrasound in Medicine & Biology
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