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Aurélien Baelde, Jérôme Laurent, Pierre Millien, Richard Coulette, Warida Ben Khalifa, Frédéric Jenson, Fan Sun, Mathias Fink, Claire Prada
The effect of microstructural elongation on ultrasonic backscattered fields was studied. Two methods for determining the elongation direction of macrozones in titanium alloys, using the anisotropic spatial coherence of the backscattered field, are presented. Both methods use a phased array attached on a rotative holder that records the array response matrix at several angles. Two titanium alloys were investigated: TA6V and Ti17. TA6V exhibited a strong macrozone elongation, whereas Ti17 macrozones were found equiaxial...
September 20, 2017: Ultrasonics
Gevanio Bezerra de Oliveira Filho, Marcos Veríssimo de Oliveira Cardoso, José Wanderlan Pontes Espíndola, Dayane Albuquerque Oliveira E Silva, Rafaela Salgado Ferreira, Pollyanne Lacerda Coelho, Pâmela Silva Dos Anjos, Emanuelle de Souza Santos, Cássio Santana Meira, Diogo Rodrigo Magalhaes Moreira, Milena Botelho Pereira Soares, Ana Cristina Lima Leite
Chagas disease is one of the most significant health problems in the American continent. benznidazole (BDZ) and nifurtimox (NFX) are the only drugs approved for treatment and exhibit strong side effects and ineffectiveness in the chronic stage, besides different susceptibility among T. cruzi DTUs (Discrete Typing Units). Therefore, new drugs to treat this disease are necessary. Thiazole compounds have been described as potent trypanocidal agents. Here we report the structural planning, synthesis and anti-T...
September 22, 2017: European Journal of Medicinal Chemistry
Li Juel Mortensen, Martin Blomberg Jensen, Peter Christiansen, Ann-Margrethe Rønholt, Anne Jørgensen, Hanne Frederiksen, John E Nielsen, Anand C Loya, Birgitte Grønkær Toft, Niels E Skakkebæk, Ewa Rajpert-De Meyts, Anders Juul
Context: Testotoxicosis is an autosomal dominant, male-limited disorder. Activating mutations in the Luteinizing Hormone Receptor gene (LHCGR) cause high autonomous testosterone secretion resulting in early-onset peripheral precocious puberty. Little is known about long-term consequences of testotoxicosis. Case Description: We present a rare case of a patient followed for 25 years with two remarkable outcomes; preserved fertility and germ cell neoplasia in situ (GCNIS)...
October 5, 2017: Journal of Clinical Endocrinology and Metabolism
Wenchao Liao, Tianyuan Chen, Chengming Wang, Wenxin Zhang, Zhangkai Peng, Xiao Zhang, Shengnan Ai, Deyong Fu, Tieying Zhou, Ping Xue
We present a focus-adjustable endoscopic probe for optical coherence tomography (OCT), which is able to acquire images with different focal planes and overcome depth-of-focus limitations by image fusing. The use of a two-way shape-memory-alloy spring enables the probe to adjust working distance over 1.5 mm, providing a large scanning range with high resolution and no sensitivity loss. Equipped with a homemade hollow-core ultrasonic motor, the probe is capable of performing an unobstructed 360 deg field-of-view distal scanning...
October 15, 2017: Optics Letters
Yu Sun, Tian-Yi Shi, Ling-Yun Zhou, Yu-Yan Zhou, Bai-Wang Sun, Xiao-Ping Liu
Platinum-based drugs are used to treat a variety of cancers but have many side effects such as nephrotoxicity and neurotoxicity. A folate-decorated nanoparticles system with a good drug payload can selectively deliver drugs into folate receptor (FR)-overexpressing cancer cells to prevent the shortcomings of platinum-based chemotherapy. Here, folate-decorated and near-infrared (NIR) laser-activated nanoparticles (abbreviated as Pt(IV)-FINPs) were prepared via ultrasonic self-assembling of platinum(IV) prodrug c,c,t-Pt(NH3)2Cl2(OOCCH2CH2COOH)2, folic acid (FA)-functionalized lipid DSPE-PEG-FA and NIR fluorescent dye indocyanine green (ICG)...
October 13, 2017: Journal of Microencapsulation
Amr Badawy, Satoru Seo, Rei Toda, Hiroaki Fuji, Takamichi Ishii, Kojiro Taura, Kentaro Yasuchika, Toshimi Kaido, Shinji Uemoto
INTRODUCTION: THUNDERBEAT (TB) is a novel device that uses both ultrasonic and advanced bipolar energies for hemostasis. Several recent human studies have proved the safety and efficacy of TB in different surgical procedures, but there have been no similar studies about its efficacy in hepatic parenchymal transection. Therefore, the aim of the study was to assess the safety and efficacy of the TB device in laparoscopic liver resection. METHODS: This retrospective study compared TB and ultrasonic Harmonic devices in 80 patients who underwent laparoscopic liver resection from 2010 to 2016 in our institution...
October 12, 2017: Asian Journal of Endoscopic Surgery
A Balcerzak
Two samples of triacylglycerols i.e., olive oil and triolein, and one sample of diacylglycerol were investigated. In the course of compression, the density of the samples was determined by measurements of the change of piston position in a pressure chamber and volume correction due to chamber expansion under pressure. The speed of sound was evaluated from the time of flight of an ultrasonic impulse between emitting and receiving transducers placed in the high pressure chamber. The adiabatic compressibility, the intermolecular free length, the molar volume, the van der Waals' constant b and the surface tension were evaluated from the density, the speed of sound and the average molecular mass...
2017: Journal of the American Oil Chemists' Society
Juncen Zhou, Micael Alonso Frank, Yuyun Yang, Aldo R Boccaccini, Sannakaisa Virtanen
A local drug delivery system consisting of superhydrophobic titanium oxide nanotube (S-TNTs) arrays and ultrasonic-controlled release trigger was developed in this work. Hydrophilic TNTs arrays are converted into superhydrophobic after being treated by 1H,1H,2H,2H- perfluorooctyl-triethoxysilane (POTS). S-TNTs arrays serving as a drug-carrying vehicle require no extra sealing treatment due to the excellent isolation effect from the trapped air layer on the surface. Different amounts of drugs could be loaded into S-TNTs arrays by control of the structure of arrays (including length and diameter of tubes) and the original amount of drug in the drug-loading solution...
January 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
L M Bryson, D Fernandez Rivas, C Boutsioukis
AIM: To compare the pre-sterilization cleaning of rotary Ni-Ti files of different sizes previously used a. ex vivo and b. clinically by a washer disinfector, a regular ultrasonic bath, and the same ultrasonic bath in combination with a recently developed cavitation intensifying method. METHODOLOGY: Two sets of two hundred rotary Ni-Ti files, one previously used ex vivo and another one used clinically, were collected from the undergraduate and postgraduate clinics of the Academic Centre for Dentistry Amsterdam (ACTA)...
October 12, 2017: International Endodontic Journal
Peilu Liu, Xinghua Li, Haopeng Li, Zhikun Su, Hongxu Zhang
In order to improve the accuracy of ultrasonic phased array focusing time delay, analyzing the original interpolation Cascade-Integrator-Comb (CIC) filter, an 8× interpolation CIC filter parallel algorithm was proposed, so that interpolation and multichannel decomposition can simultaneously process. Moreover, we summarized the general formula of arbitrary multiple interpolation CIC filter parallel algorithm and established an ultrasonic phased array focusing time delay system based on 8× interpolation CIC filter parallel algorithm...
October 12, 2017: Sensors
Charlie Demene, Jérome Baranger, Miguel Bernal, Catherine Delanoe, Stéphane Auvin, Valérie Biran, Marianne Alison, Jérome Mairesse, Elisabeth Harribaud, Mathieu Pernot, Mickael Tanter, Olivier Baud
Functional neuroimaging modalities are crucial for understanding brain function, but their clinical use is challenging. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to allow for the spatiotemporal identification of brain activation through neurovascular coupling in rodents. Using a customized flexible and noninvasive headmount, we demonstrate in human neonates that real-time functional ultrasound imaging (fUSI) is feasible by combining simultaneous continuous video-electroencephalography (EEG) recording and ultrafast Doppler (UfD) imaging of the brain microvasculature...
October 11, 2017: Science Translational Medicine
Marit E Aardal, Lene L Svendsen, Sverre Lehmann, Tomas M Eagan, Ingvild Haaland
OBJECTIVE: The aim of this pilot study was to compare spirometric values obtained with different types of spirometers, spirometers of same type, and repeated measurements with the same spirometer in a pulmonary function laboratory setting. RESULTS: 12 healthy volunteers performed spirometry on four hot-wire (SensorMedics), two ultrasonic (Spirare) and one wedge-bellows (Vitalograph S) spirometers, according to ATS/ERS (American Thoracic Society/European Respiratory Society) guidelines...
October 10, 2017: BMC Research Notes
Sarah L Pachtman, Sleiman R Ghorayeb, Matthew J Blitz, Kemoy Harris, Nidhi Vohra, Cristina P Sison, Burton L Rochelson
No abstract text is available yet for this article.
October 10, 2017: American Journal of Perinatology
Karel Folens, Thibaut Van Acker, Eduardo Bolea-Fernandez, Geert Cornelis, Frank Vanhaecke, Gijs Du Laing, Sebastien Rauch
Elevated platinum (Pt) concentrations are found in road dust as a result of emissions from catalytic converters in vehicles. This study investigates the occurrence of Pt in road dust collected in Ghent (Belgium) and Gothenburg (Sweden). Total Pt contents, determined by tandem ICP-mass spectrometry (ICP-MS/MS), were in the range of 5 to 79ngg(-1), comparable to the Pt content in road dust of other medium-sized cities. Further sample characterization was performed by single particle (sp) ICP-MS following an ultrasonic extraction procedure using stormwater runoff for leaching...
October 7, 2017: Science of the Total Environment
Wangbing Zhang, Mei Wei, Wei Song, Yi-Xuan Gong, Xin-An Yang
In this paper, we firstly report the development of a highly sensitive and economical method for accurate analysis of pyridaben residues on fruits based on dual-frequency ultrasonic treatment (DFUT) and flow injection chemiluminescence (CL) detection. The DFUT device is constituted by integrating an ultrasonic bath with an ultrasonic probe. Two quartz glass coils (QGC) with different structures have been designed and applied to evaluate the function of DFUT in the detection process. Recorded data showed that DFUT is an effective method for improving the pyridaben CL signal...
October 10, 2017: Journal of Agricultural and Food Chemistry
Giulia Matrone, Alessandro Ramalli, Alessandro Stuart Savoia, Fabio Quaglia, Gloria Castellazzi, Patrizia Morbini, Marco Piastra
The possibility to perform an early and repeatable assessment of imaging performance is fundamental in the design and development process of new ultrasound (US) probes. Particularly, a more realistic analysis with application-specific imaging targets can be extremely valuable to assess the expected performance of US probes in their potential clinical field of application. The experimental protocol presented in this work was purposely designed to provide an application-specific assessment procedure for newly-developed US probe prototypes based on Capacitive Micromachined Ultrasonic Transducer (CMUT) technology in relation to brain imaging...
September 24, 2017: Journal of Visualized Experiments: JoVE
Ye Zou, Huan Bian, Pengpeng Li, Zhilan Sun, Chong Sun, Muhan Zhang, Zhiming Geng, Weimin Xu, Daoying Wang
The aim of this study was to investigate the optimal conditions of ultrasound-assisted alkaline extraction (UAAE) on pork liver protein isolate (UPLPI) and its physico-chemical properties. Response surface methodology was used to determine the optimal conditions for UAAE, which were at ultrasonic power 265 W, ultrasonic time 42 min, NaOH concentration 0.80%, temperature 50°C, and solvent/raw material ratio 70. The extraction yield and efficiency of UPLPI were significantly improved over the conventional alkaline extraction (PLPI)...
October 10, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
Ran Tao, Chengzhang Wang, Changwei Zhang, WenJun Li, Hao Zhou, Hongxia Chen, Jianzhong Ye
The structure and bioactivity of Ginkgo biloba leaves polyprenol (GBP) are similar to that of dolichol which widely exists in human and mammalian organs. GBP possesses potential pharmacological activities against cancer. This study involved oil-in-water type nanoemulsion (NE) loading GBP was prepared by dissolving polyprenol in nanoemulsion of sodium tripolyphosphate (TPP)/TiO2 solution, Triton X-100, and 1-octanol by inversed-phase emulsification (EIP) and ultrasonic emulsification (UE) method. Folic acid (FA)-coupled chitosan (CS) nanoparticles (NPs), GBP-FA-CS-NPs and GBP-TiO2-FA-CS-NPs, were fabricated by ionic cross-linking of positively charged FA-CS conjugates and negatively charged nanoemulsion with TPP/TiO2...
October 9, 2017: Biological Trace Element Research
Pei-Chi Wu, Ewelina P Dutkiewicz, Pawel L Urban
The purpose of analytical extractions is to simplify sample matrix without losing analyte molecules. Here we present a technique of extracting volatile compounds by scavenging gas-phase molecules with tiny liquid droplets (<10 μm). A cool mist of the extracting solvent is generated by an ultrasonic transducer, transferred to the headspace of the sample chamber under atmospheric conditions, and pushed by a small pressure difference toward a condenser. By slowly passing over the sample, the microdroplets extract volatile species present in the sample headspace, and they coalesce in a cooled zone...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Ji Hyun Lee, Il Je Yu
Exposure to the humidifier disinfectant, polyhexamethylene guanidine phosphate (PHMG), in mists generated from ultrasonic humidifiers was studied in a simulation chamber and apartment rooms. PHMG is suspected as a causative agent of lung disease in Korea residences. In the simulation-chamber study, the amount of disinfectant discharged from three different ultrasonic humidifiers was measured. Mists generated at 1, 2, and 4 times the recommended amount of disinfectant were sampled with an impinger, and the effect of relative humidity (RH) on airborne disinfectant concentration was studied by changing RH from 60%-70% to 90%-100%...
January 1, 2017: Toxicology and Industrial Health
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