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https://www.readbyqxmd.com/read/28213779/adenoid-bacterial-colonization-in-a-paediatric-population
#1
João Subtil, João Carlos Rodrigues, Lúcia Reis, Luís Freitas, Joana Filipe, Alberto Santos, Carlos Macor, Aida Duarte, Luisa Jordao
Adenoids play a key role in both respiratory and ear infection in children. It has also been shown that adenoidectomy improves these symptoms in this population. The main goal of the present study was to evaluate adenoid bacterial colonization and document a possible relation with infectious respiratory disease. A prospective observational study was designed to evaluate the proposed hypothesis in a paediatric population submitted to adenoidectomy by either infectious or non-infectious indications and compare these two cohorts...
February 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28213099/polymeric-nanoparticles-loaded-with-dexamethasone-or-%C3%AE-tocopheryl-succinate-to-prevent-cisplatin-induced-ototoxicity
#2
Sergio Martín-Saldaña, Raquel Palao-Suay, María Rosa Aguilar, Rafael Ramírez-Camacho, Julio San Román
: The aim of this work is the development of highly protective agents to be administered locally within the middle ear to avoid cisplatin-induced ototoxicity, which affects to 100% of the clinical patients at ultra-high concentrations (16 mg/kg). The protective agents are based on polymeric nanoparticles loaded with dexamethasone or α-tocopheryl succinate as anti-inflammarory and anti-apoptotic molecules. Dexamethasone and α-tocopheryl succinate are poorly soluble in water and present severe side effects when systemic administered during long periods of time...
February 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28212124/extracranial-meningioma-presenting-as-an-eyebrow-mass
#3
Do Hun Lee, Ho Seup Sim, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
Meningiomas originate in the central nervous system and are the most common intracranial benign tumor. However, although rarely, they can develop extracranially. Primary extracranial meningiomas are frequently misdiagnosed, resulting in inappropriate clinical management. The most common sites of extracranial meningiomas include the skull, scalp, orbit, nose, paranasal sinuses, middle ear, neck, and skin. A 77-year-old woman presented with a mass on her left eyebrow. Computed tomography revealed an enhancing soft tissue mass in the left frontal area...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28209807/blast-injury-of-the-ear-by-massive-explosion-a-review-of-41-cases
#4
Stanislas Ballivet de Régloix, A Crambert, O Maurin, Q Lisan, S Marty, Y Pons
BACKGROUND: Blast injuries in modern warfare are common, and the ear is often affected as it is an effective pressure transducer. This study aimed to evaluate military blast injuries of the ear. METHODS: From May 2002 to October 2014, all patients referred to two military hospitals near Paris, France following exposure to massive explosions were analysed. RESULTS: Among the 41 patients (82 ears), 36 of them reported tinnitus, 25 hearing loss, 14 earache and 8 vertigo...
February 16, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28208857/emergence-of-hospital-acquired-carbapenem-resistant-non-fermenters-in-teaching-institute
#5
Hariom Sharan, Neeraj Katare, Aparna Pandey, Ganesh Shivmurti Bhatambare, Trupti Bajpai
INTRODUCTION: Non-Fermenting Gram Negative Bacilli (NFGNB) are emerging now-a-days because of their tendency to colonize various surfaces and inherent resistance to commonly used disinfectants. They are responsible for multi-drug resistant hospital acquired infections. Detection of carbapenem resistance mechanisms is essential for treatment and infection control purpose as can spread to other organisms causing hospital outbreaks. AIM: To characterize non-fermenters from various clinical samples and to detect different carbapenem resistance mechanisms in meropenem resistant isolates...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207625/a-three-dimensional-geometric-morphometric-study-to-quantify-temporal-bone-growth-and-its-consequences-for-the-success-of-implanting-bone-anchored-hearing-devices
#6
Sebastian Schilde, Stefan K Plontke, Torsten Rahne
OBJECTIVE: A computed tomography (CT)-based morphological-investigation to describe temporal bone growth and to devise a predictive test of the likely success of Bonebridge implantation into the growing mastoid region of the temporal bone in young patients. STUDY DESIGN: Retrospective cross-sectional study. SETTING: University Hospital Halle (Saale), Germany. PATIENTS: Two cohorts participated. This first, of patients aged less than 21 years, comprised 42 men, and 33 women patients...
February 15, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28207578/the-impact-of-a-cochlear-implant-electrode-array-on-the-middle-ear-transfer-function
#7
David Pazen, Andreas Anagiotos, Maike Nünning, Antoniu-Oreste Gostian, Magdalene Ortmann, Dirk Beutner
OBJECTIVES: As a treatment for partial deafness with residual hearing in the lower frequency range, the combined acoustic and electric stimulation of the cochlea has become widespread. Acoustic stimulation is provided by a hearing aid's airborne sound and the electric stimulation by a cochlear implant electrode array, which may be inserted through the round window or a cochleostomy. To take advantage of that concept, it is essential to preserve residual hearing after surgery. Therefore, the intracochlear electrode array should not compromise the middle ear vibration transmission...
February 15, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28202466/time-varying-auditory-gain-control-in-response-to-double-pulse-stimuli-in-harbour-porpoises-is-not-mediated-by-a-stapedial-reflex
#8
Asger Emil Munch Schrøder, Kristian Beedholm, Peter Teglberg Madsen
Echolocating animals reduce their output level and hearing sensitivity, presumably to stabilize the perceived echo intensity during target approaches. In bats this variation in hearing sensitivity is formed by a call-induced stapedial reflex that tapers off over time after the call. Here we test the hypothesis that a similar mechanism exists in toothed whales by subjecting a trained harbour porpoise to a series of double sound pulses varying in delay and frequency, while measuring the magnitudes of the evoked ABRs...
February 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28198721/the-chronic-otitis-media-benefit-inventory-combi-development-and-validation-of-a-dynamic-quality-of-life-questionnaire-for-chronic-ear-disease
#9
John S Phillips, Mark Haggard, Helen Spencer, Matthew Yung
OBJECTIVE: This study introduces a change-oriented short-form health-related quality of life questionnaire suited to symptoms of adult chronic middle ear disease and its consequences, and describes its properties. STUDY DESIGN: Two-centre prospective correlational study primarily for instrument development. SETTING: Two otology secondary care centers in England. PATIENTS: Fifty-two consecutive adult patients with active chronic otitis media undergoing surgery...
February 14, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28195998/a-meta-analysis-on-the-diagnostic-performance-of-non-echoplanar-diffusion-weighted-imaging-in-detecting-middle-ear-cholesteatoma-10-years-on
#10
Ravi K Lingam, Paul Bassett
OBJECTIVE: To describe via a meta-analysis of the published literature, the performance of non-echo-planar diffusion weighted imaging (DWI) in detecting middle ear cholesteatoma. METHODOLOGY: A systematic review of the published literature was performed to identify original studies evaluating the diagnostic performance of non-echo-planar DWI in detecting middle ear cholesteatoma. Only studies with surgical correlation were included. A bi-variate meta-analysis and hierarchical summary receiver operating characteristic model was performed...
February 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28194509/fetal-facial-nerve-course-in-the-ear-region-revisited
#11
Zhe Wu Jin, Kwang Ho Cho, Hiroshi Abe, Yukio Katori, Gen Murakami, Jose Francisco Rodríguez-Vázquez
PURPOSE: The aim of this study was to re-examine the structures that determine course of the facial nerve (FN) in the fetal ear region. MATERIALS AND METHODS: We used sagittal or horizontal sections of 28 human fetuses at 7-8, 12-16, and 25-37 weeks. RESULTS: The FN and the chorda tympani nerve ran almost parallel until 7 weeks. The greater petrosal nerve (GPN) ran vertical to the distal FN course due to the trigeminal nerve ganglion being medial to the geniculate ganglion at 7 weeks...
February 14, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28192382/endoscopic-management-of-middle-ear-paragangliomas-a-case-series
#12
Daniel E Killeen, Cameron C Wick, Jacob B Hunter, Alejandro Rivas, George B Wanna, João Flávio Nogueira, Joe Walter Kutz, Brandon Isaacson
OBJECTIVE: To investigate the efficacy and safety of endoscopic middle ear paraganglioma (glomus tympanicum) resection. STUDY DESIGN: Case series with chart review. SETTING: Multi-institutional tertiary university medical centers. PATIENTS: Adult patients with middle ear paragangliomas treated via a transcanal endoscopic approach from 1/2012 to 11/2015. INTERVENTION: All tumors were initially approached via a transcanal endoscopic technique...
March 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28192381/plasmacytoma-of-the-temporal-bone-a-great-imitator-report-of-seven-cases-and-comprehensive-review-of-the-literature
#13
Alex D Sweeney, Jacob B Hunter, S Vincent Rajkumar, John I Lane, Dragan Jevremovic, Matthew L Carlson
OBJECTIVES: To describe the clinical presentation, radiological features, and outcome of patients with plasmacytoma of the temporal bone. METHODS: Multicenter retrospective case series of all patients diagnosed with plasmacytoma of the temporal bone between 1990 and 2015. Comprehensive literature review of all previously published cases. RESULTS: A total of seven patients (average age, 57.3 yr; 57% women) met inclusion criteria. Three (43%) had a known history of multiple myeloma (MM)...
March 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28185669/electrical-stimulation-and-monitoring-devices-of-the-cns-an-imaging-review
#14
REVIEW
Sohil H Patel, Casey H Halpern, Timothy M Shepherd, Vincent M Timpone
Functional neurosurgery is a rapidly growing field with exciting future potential applications. This article describes currently used implanted electronic devices for neurologic stimulation and monitoring. The devices to be reviewed include invasive EEG electrodes, deep brain stimulator, motor cortex stimulator, responsive neurostimulation, osteo-integrated hearing aid, middle ear implant, cochlear implant, auditory brainstem implant, vagal nerve stimulator and spinal cord stimulator. Emphasis is placed on the normal components, function, positioning, potential complications and MRI safety of these devices...
February 6, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28181975/effects-of-auricular-acupressure-therapy-on-stress-and-sleep-disturbance-of-middle-aged-women-in-south-korea
#15
Nam Hyun Cha, Yi Kyun Park, Sohyune R Sok
This study sought to examine the effect of auricular acupressure therapy on the stress and sleep status of middle-aged women in South Korea. A quasi-experimental pretest/posttest control group design was employed. The study sample consisted of 67 middle-aged women (experimental: 35 samples; control: 32 samples) in Seoul, South Korea. Auricular acupressure therapy including the auricular acupressure needle on the skin paper tape was applied on an ear for 2 weeks, 2 times per week. The acupoints were Gyogam, Sinmun, Bushin, Naebunbi, and Pijilha...
March 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/28180922/effect-of-btxa-on-inhibiting-hypertrophic-scar-formation-in-a-rabbit-ear-model
#16
Dong-Qing Liu, Xiao-Jing Li, Xiao-Juan Weng
BACKGROUND: Hypertrophic scar (HS) is a refractory skin disease caused by major physical damage or other inflammation. Some reports found that botulinum toxin type A (BTXA) could be an alternative treatment of the HS. Therefore, the authors studied the effects of BTXA on the treatment of HS and the dose response of BTXA. METHODS: Hypertrophic scars were harvested from the ears of 18 young adult New Zealand big-eared rabbits and treated with BTXA or triamcinolone acetonide (TAC) in vivo experiment...
February 8, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28180050/utility-of-an-ultrasonic-aspirator-in-transcanal-endoscopic-resection-of-temporal-bone-paraganglioma
#17
Brendan P O'Connell, Jacob B Hunter, Matthew L Carlson, Brandon Isaacson, Alejandro Rivas, George B Wanna
The objective of this study was to evaluate the role of removing middle ear paragangliomas using an ultrasonic aspirator (UA) through a transcanal, exclusively endoscopic approach. Three consecutive patients undergoing transcanal endoscopic resection of middle ear paragangliomas using an UA were retrospectively studied. The primary outcome measure was achieving gross total tumor resection. Secondary outcomes included postoperative hearing and early convalescence. Two glomus tympanicum tumors and one small glomus jugulare were included, and complete tumor resection was achieved endoscopically in all cases...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28179517/a-new-developmental-mechanism-for-the-separation-of-the-mammalian-middle-ear-ossicles-from-the-jaw
#18
Daniel J Urban, Neal Anthwal, Zhe-Xi Luo, Jennifer A Maier, Alexa Sadier, Abigail S Tucker, Karen E Sears
Multiple mammalian lineages independently evolved a definitive mammalian middle ear (DMME) through breakdown of Meckel's cartilage (MC). However, the cellular and molecular drivers of this evolutionary transition remain unknown for most mammal groups. Here, we identify such drivers in the living marsupial opossum Monodelphis domestica, whose MC transformation during development anatomically mirrors the evolutionary transformation observed in fossils. Specifically, we link increases in cellular apoptosis and TGF-BR2 signalling to MC breakdown in opossums...
February 8, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28178138/etiology-of-acute-otitis-media-and-serotype-distribution-of-streptococcus-pneumoniae-and-haemophilus-influenzae-in-chilean-children-5-years-of-age
#19
Andres Rosenblut, Carla Napolitano, Angelica Pereira, Camilo Moreno, Devayani Kolhe, Alejandro Lepetic, Eduardo Ortega-Barria
The impact of bacterial conjugate vaccines on acute otitis media (AOM) is affected by several factors including population characteristics, bacterial etiology and vaccine conjugation method, carrier, and coverage. This study estimated the baseline etiology, distribution, and antibiotic susceptibility of bacterial serotypes that causes AOM in children aged <5 years in a public setting in Santiago, Chile.Children aged ≥3 months and <5 years referred to the physician for treatment of AOM episodes (with an onset of symptoms <72 h) were enrolled between September 2009 and September 2010...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28178096/relative-location-of-fundus-meatus-acustici-interni-via-porus-acusticus-internus-in-facial-nerve-decompression
#20
Xu Liu, Haodong Wang, Kailiang Cheng, Youqiong Li
Facial neural edema is the pathophysiological base of Bell's palsy. The middle cranial fossa approach is used to relieve the oppression of facial nerve at its most narrow course in the facial canal. In this research, the authors mainly discussed the internal auditory canal segment of facial nerve, completely in the shadow of the bony structure, which is inconvenient for transmastoid decompression. Therefore, the objective was to explore the definite position of the fundus meatus acustici interni from internal acoustic pore...
February 7, 2017: Journal of Craniofacial Surgery
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