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https://www.readbyqxmd.com/read/29227448/cochlear-implantation-in-chronic-otitis-media-with-cholesteatoma-and-open-cavities-long-term-surgical-outcomes
#1
Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Manjunath Dandinarasaiah, Antonio Caruso, Mario Sanna
OBJECTIVES: To evaluate the long-term surgical outcomes of cochlear implantation (CI) in chronic otitis media (COM) with cholesteatoma and open cavities using subtotal petrosectomy (STP). To review device explantation (DE) patients and reimplantation considerations. STUDY DESIGN: Retrospective review. SETTING: Otology and skull base center. PATIENTS AND METHODS: Charts of 35 patients (36 ears) with COM with cholesteatoma, including open cavities, who underwent CI were reviewed for surgical outcomes and DE...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29224768/newborn-hearing-screening-failure-and-maternal-factors-during-pregnancy
#2
Yehuda Schwarz, Gabriel N Kaufman, Sam J Daniel
OBJECTIVE: Temporary conductive hearing loss due to amniotic fluid accumulation in the middle ear cavity may lead to failure (false positive) in newborn hearing screening tests. The aim of this study was to identify whether amniotic fluid index has association with failure of the initial newborn otoacoustic emission (OAE) screening test. METHODS: A cohort study in a tertiary hospital center (Royal Victoria Hospital, Montréal) was constructed from 70 newborns that failed the OAE test, but passed a subsequent auditory brainstem response (ABR) test, and 75 randomly selected newborns that passed initial otoacoustic emission testing...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224754/prevalence-of-chronic-ear-disease-among-hiv-children-in-sub-saharan-africa
#3
David C Ianacone, Alden F Smith, Margaretha L Casselbrant, Robbert J H Ensink, Farrel Buchinsky, Abebe Melaku, Glenn Isaacson
OBJECTIVES: To determine the prevalence of chronic ear disease in HIV+, highly active anti-retroviral therapy (HAART)-treated children and compare this to the prevalence in healthy children of similar age living in a similar setting. INTRODUCTION: From previous clinical work in Ethiopia, we suspected that chronic middle ear disease was common both in the general pediatric population and especially among children with HIV/AIDS. Few studies have examined the prevalence of chronic ear disease in HIV + children, particularly in those treated with HAART...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29222532/acute-solar-retinopathy-imaged-with-adaptive-optics-optical-coherence-tomography-angiography-and-en-face-optical-coherence-tomography
#4
Chris Y Wu, Michael E Jansen, Jorge Andrade, Toco Y P Chui, Anna T Do, Richard B Rosen, Avnish Deobhakta
Importance: Solar retinopathy is a rare form of retinal injury that occurs after direct sungazing. Objective: To enhance understanding of the structural changes that occur in solar retinopathy by obtaining high-resolution in vivo en face images. Design, Setting, and Participant: Case report of a young adult woman who presented to the New York Eye and Ear Infirmary with symptoms of acute solar retinopathy after viewing the solar eclipse on August 21, 2017...
December 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29217752/mapping-the-distribution-of-stem-progenitor-cells-across-the-middle-ear-during-homeostasis-and-inflammation
#5
Abigail S Tucker, Carlene J Dyer, Juan M Fons Romero, Tathyane H N Teshima, Jennifer C Fuchs, Hannah Thompson
The middle ear epithelium is derived from neural crest and endoderm, which line distinct regions of the middle ear cavity. Here we investigate the distribution of putative stem cell markers in the middle ear combined with an analysis of the location of label retaining cells (LRCs) to create a map of the middle ear mucosa. We show that proliferating cells and LRCs were associated with specific regions of the ear epithelium, concentrated in the hypotympanum at the base of the auditory bulla and around the ear drum...
December 7, 2017: Development
https://www.readbyqxmd.com/read/29217746/semiautomated-middle-ear-volume-measurement-as-a-predictor-of-postsurgical-outcomes-for-congenital-aural-atresia
#6
S J Kabadi, D S Ruhl, S Mukherjee, B W Kesser
BACKGROUND AND PURPOSE: Middle ear space is one of the most important components of the Jahrsdoerfer grading system (J-score), which is used to determine surgical candidacy for congenital aural atresia. The purpose of this study was to introduce a semiautomated method for measuring middle ear volume and determine whether middle ear volume, either alone or in combination with the J-score, can be used to predict early postoperative audiometric outcomes. MATERIALS AND METHODS: A retrospective analysis was conducted of 18 patients who underwent an operation for unilateral congenital aural atresia at our institution...
December 7, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29214174/feasibility-of-round-window-stimulation-by-a-novel-electromagnetic-microactuator
#7
Wouter Johannes van Drunen, Mathias Mueller, Anatoly Glukhovskoy, Rolf Salcher, Marc Christopher Wurz, Thomas Lenarz, Hannes Maier
Introduction: Most implantable hearing aids currently available were developed to compensate the sensorineural hearing loss by driving middle ear structures (e.g., the ossicles). These devices are successfully used in round window (RW) stimulation clinically, although this was initially not the intended use. Here, a novel microactuator, specifically designed for RW stimulation, was tested in human temporal bones to determine actuator performance and applicability. Methods: Stapes footplate response to RW stimulation was determined experimentally in human temporal bones and the obtained sound pressure output level was estimated...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29210946/transcanal-endoscopic-ear-surgery-to-treat-middle-ear-cholesteatoma-should-be-performed-cautiously
#8
Zhengcai Lou
No abstract text is available yet for this article.
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29210944/stapes-release-in-tympanosclerosis
#9
Es-Hak Bedri, Nebiat Teferi, Miriam Redleaf
: Tympanosclerosis in the middle ear space is common in Ethiopia and often involves the ossicles and particularly the stapes. Ear operations in Ethiopia are relatively expensive in this country of limited medical resources and a low average living wage. In this setting, 2-stage operations using prostheses become prohibitively expensive. Therefore, the recommended 2-stage approach for tympanic membrane perforation with tympanosclerosis and stapes fixation is impractical for Ethiopia.We present a series of 67 patients who had a single stage tympanoplasty, removal of tympanosclerosis from the stapes suprastructure, and ossicular chain reconstruction using ossicular interposition...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29210943/survey-of-the-american-neurotology-society-on-cochlear-implantation-part-2-surgical-and-device-related-practice-patterns
#10
Matthew L Carlson, Brendan P O'Connell, Christine M Lohse, Colin L Driscoll, Alex D Sweeney
OBJECTIVE: To examine surgical and device-related cochlear implant practice patterns across centers in the United States. METHODS: Cross-sectional survey of the American Neurotology Society (ANS). RESULTS: A total of 81 surveys were returned from ANS members who report regular involvement in cochlear implant care. Overall there was a broad distribution in age and clinical experience, with most respondents reporting Accreditation Council for Graduate Medical Education (ACGME) accreditation in neurotology and employment at an academic center...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29209853/3d-endoscopic-ear-surgery-a-clinical-pilot-study
#11
Daniele Bernardeschi, Ghizlene Lahlou, Daniele De Seta, Francesca Yoshie Russo, Isabelle Mosnier, Olivier Sterkers
OBJECTIVE: To evaluate the feasibility and efficacy of a new high-resolution 3D endoscope in endoscopic ear and lateral skull base surgery. METHODS: Eight patients, five women and three men, were included in this clinical pilot prospective study. Their age was 38 ± 17.3 years (mean ± SD, range 17-54 years). The right side was involved in five cases, and the left side in three cases. There were three cases of chronic otitis, one case of cholesteatoma of the external auditory canal, one case of otosclerosis, one case of cochlear implant surgery, and two cases of stage 2 vestibular schwannoma operated on with a retrosigmoid approach to preserve hearing...
December 5, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29205455/the-middle-and-inner-ears-of-the-palaeogene-golden-mole-namachloris-a-comparison-with-extant-species
#12
Matthew J Mason, Nigel C Bennett, Martin Pickford
Many living species of golden moles (Chrysochloridae) have greatly enlarged middle ear ossicles, believed to be used in the detection of ground vibrations through inertial bone conduction. Other unusual features of chrysochlorids include internally coupled middle ear cavities and the loss of the tensor tympani muscle. Our understanding of the evolutionary history of these characteristics has been limited by the paucity of fossil evidence. In this article, we describe for the first time the exquisitely preserved middle and inner ears of Namachloris arenatans from the Palaeogene of Namibia, visualised using computed tomography, as well as ossicles attributed to this species...
December 4, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29202035/through-the-eustachian-tube-and-beyond-a-new-miniature-robotic-endoscope-to-see-into-the-middle-ear
#13
Loris Fichera, Neal P Dillon, Dongqing Zhang, Isuru S Godage, Michael A Siebold, Bryan I Hartley, Jack H Noble, Paul T Russell, Robert F Labadie, Robert J Webster
This paper presents a novel miniature robotic endoscope that is small enough to pass through the Eustachian tube and provide visualization of the middle ear (ME). The device features a miniature bending tip previously conceived of as a small-scale robotic wrist that has been adapted to carry and aim a small chip-tip camera and fiber optic light sources. The motivation for trans-Eustachian tube ME inspection is to provide a natural-orifice-based route to the ME that does not require cutting or lifting the eardrum, as is currently required...
2017: IEEE Robotics and Automation Letters
https://www.readbyqxmd.com/read/29200185/early-vaccine-type-pneumococcal-acute-otitis-media-does-not-predispose-to-subsequent-otitis-when-compared-to-early-acute-otitis-media-due-to-other-bacterial-etiology
#14
Arto A Palmu, Mika Lahdenkari
BACKGROUND: Prevention of acute otitis media (AOM), and especially recurrence and biofilm formation, by pneumococcal conjugate vaccines (PCV) has been hypothesized to be due to prevention of early episodes triggering the vicious cycle. We tested the specific role of vaccine-type pneumococcal AOM in this hypothesis. METHODS: In the phase III randomized, double-blind FinOM Vaccine Trial conducted in 1995-99 children received PCV7 or hepatitis B vaccine as control at 2/4/6/12 months of age and were followed for AOM...
December 1, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29197892/relapse-of-b-cell-acute-lymphoblastic-leukaemia-presenting-as-right-aural-polyp-with-facial-and-mandibular-nerves-palsy
#15
C Shiun Chuen, M K Md Daud, N A Che Jalil, H Hazmi
A patient presenting with an ear polyp is a common finding in otorhinolaryngology practice. The common causes include chronic otitis media and cholesteatoma. We report an adult female patient with a history of acute leukaemia presenting with chronic otitis media symptoms and right ear polyp. She was subsequently diagnosed as relapse of B-cell acute lymphoblastic leukaemia based on histopathological examination. The presentation may be similar to an inflammatory pathology of the middle ear, making it misleading...
October 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/29195482/the-effects-of-varying-tympanic-membrane-material-properties-on-human-middle-ear-sound-transmission-in-a-three-dimensional-finite-element-model
#16
Kevin N O'Connor, Hongxue Cai, Sunil Puria
An anatomically based three-dimensional finite-element human middle-ear (ME) model is used to test the sensitivity of ME sound transmission to tympanic-membrane (TM) material properties. The baseline properties produce responses comparable to published measurements of ear-canal input impedance and power reflectance, stapes velocity normalized by ear-canal pressure (PEC), and middle-ear pressure gain (MEG), i.e., cochlear-vestibule pressure (PV) normalized by PEC. The mass, Young's modulus (ETM), and shear modulus (GTM) of the TM are varied, independently and in combination, over a wide range of values, with soft and bony TM-annulus boundary conditions...
November 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29195446/a-common-microstructure-in-behavioral-hearing-thresholds-and-stimulus-frequency-otoacoustic-emissions
#17
James B Dewey, Sumitrajit Dhar
Behavioral hearing thresholds and otoacoustic emission (OAE) spectra often exhibit quasiperiodic fluctuations with frequency. For behavioral and OAE responses to single tones-the latter referred to as stimulus-frequency otoacoustic emissions (SFOAEs)-this microstructure has been attributed to intracochlear reflections of SFOAE energy between its region of generation and the middle ear boundary. However, the relationship between behavioral and SFOAE microstructures, as well as their presumed dependence on the properties of the SFOAE-generation mechanism, have yet to be adequately examined...
November 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29193857/prenatal-and-postnatal-development-of-the-mammalian-ear
#18
REVIEW
Nicola Powles-Glover, Mark Maconochie
The ear can be subdivided into three distinct parts, each with significantly distinct structural and functional differences, the outer, middle, and inner ear, the latter housing the specialized sensory hair cells that act as transducers. There are numerous manuscripts documenting the anatomical development of the inner, middle, and outer ear in humans, rodents, chick, and zebrafish, dating back to the early 20th Century, and these developmental processes of these components are further compared in a number of review articles (Anthwal & Thompson, ; Basch, Brown, Jen, & Groves, ; Sai & Ladher, )...
November 28, 2017: Birth Defects Research
https://www.readbyqxmd.com/read/29192624/role-of-trichloroacetic-acid-and-gelfoam-in-closure-of-tympanic-membrane-perforations
#19
M Singh, M Kaur, B Singh, K Singh, A Singh, A Kaur
OBJECTIVE: The aim of the study was to study the closure of dry central type of tympanic membrane perforations by chemical cautery and improvement of hearing, to analyse the effect of Gelfoam on nonhealing small tympanic membrane perforations, and to examine the relevance of conservative means of closure of tympanic membrane perforations as an office procedure. MATERIALS AND METHODS: In this study, 100 patients attending the outpatient department were enrolled. Cautery of perforation margin was carried out with 50% trichloroacetic acid (TCA)...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29191962/nontypeable-haemophilus-influenzae-lysates-increase-heterogeneous-nuclear-ribonucleoprotein-secretion-and-exosome-release-in-human-middle-ear-epithelial-cells
#20
Stéphanie Val, Anna Krueger, Marian Poley, Ariella Cohen, Kristy Brown, Aswini Panigrahi, Diego Preciado
Nontypeable Haemophilus influenzae (NTHi), one of the most common acute otitis media (OM) pathogens, is postulated to promote middle-ear epithelial remodeling in the progression of OM from acute to chronic. The goal of this study was to examine early quantitative proteomic secretome effects of NTHi lysate exposure in a human middle-ear epithelial cell (HMEEC) line. NTHi lysates were used to stimulate HMEEC, and conditional quantitative stable isotope labeling with amino acids in cell culture of cell secretions was performed...
November 30, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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