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https://www.readbyqxmd.com/read/29036194/micromeryx-eiselei-a-new-moschid-species-from-steinheim-am-albuch-germany-and-the-first-comprehensive-description-of-moschid-cranial-material-from-the-miocene-of-central-europe
#1
Manuela Aiglstorfer, Loïc Costeur, Bastien Mennecart, Elmar P J Heizmann
Moschids are enigmatic pecoran ruminants whose phylogeny is still not fully understood. So far we know only little of the family's early evolutionary history and the origin of the modern genus, Moschus. Here we present a comprehensive description of cranial material, including the ear region and the dentition, of fossil moschid material from the Middle Miocene locality Steinheim am Albuch (13.5 Ma; Germany). This study provides the first exhaustive dataset for the cranial osteology of Micromeryx flourensianus, the most likely oldest true moschid...
2017: PloS One
https://www.readbyqxmd.com/read/29034852/comparison-of-direct-plating-and-broth-enrichment-culture-methods-for-detection-of-potential-bacterial-pathogens-in-respiratory-secretions
#2
Ravinder Kaur, Jareth Wischmeyer, Matthew Morris, Michael E Pichichero
OBJECTIVE: We compared the recovery of potential respiratory bacterial pathogens and normal flora from nasopharyngeal specimens collected from children during health and at the onset of acute otitis media (AOM) by selective direct-plating and overnight broth-enrichment. METHODS: Overall, 3442 nasal wash (NW) samples collected from young children were analysed from a 10-year prospective study. NWs were cultured by (1) direct-plating to TSAII/5 % sheep blood agar and chocolate agar plates and (2) overnight broth-enrichment in BacT/ALERT SA-broth followed by plating...
October 16, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29031526/the-temporal-artery-island-flap-a-good-reconstructive-option-for-small-to-medium-sized-facial-defects
#3
Said Algan, Murat Kara, Hakan Cinal, Ensar Zafer Barin, Akin Inaloz, Onder Tan
PURPOSE: The reconstruction of facial defects is esthetically vital because of the unique skin color and texture of the face. The aim of this study was to show the utility of different temporal artery island flap designs for the reconstruction of upper and middle facial defects without contrast to the color and texture of the face. MATERIALS AND METHODS: This study is retrospective case series conducted from November 2004 through May 2015. Patients older than 18 years with upper and middle facial defects smaller than 5 cm were included...
September 19, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29025871/audiograms-of-three-subterranean-rodent-species-gen-fukomys-determined-by-auditory-brainstem-responses-reveal-extremely-low-high-frequency-cut-offs
#4
Patricia Gerhardt, Yoshiyuki Henning, Sabine Begall, E Pascal Malkemper
Life underground has shaped the auditory sense of subterranean mammals, shifting their hearing range to low frequencies. Mole-rats of the genus Fukomys have, however, been suggested to hear up to 18.5 kHz, unusually high for a subterranean rodent. We present audiograms of three mole-rat species, Fukomys anselli, Fukomys micklemi and the giant mole-rat Fukomys mechowii, based on evoked auditory brainstem potentials. All species showed low sensitivity and restricted hearing ranges at 60 dB SPL extending from 125 Hz to 4 kHz (5 octaves) with most sensitive hearing between 0...
October 12, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29025832/feasibility-and-acceptability-of-training-community-health-workers-in-ear-and-hearing-care-in-malawi-a-cluster-randomised-controlled-trial
#5
Wakisa Mulwafu, Hannah Kuper, Asgaut Viste, Frederik K Goplen
OBJECTIVE: To assess the feasibility and acceptability of training community health workers (CHWs) in ear and hearing care, and their ability to identify patients with ear and hearing disorders. DESIGN: Cluster randomised controlled trial (RCT). SETTING: Health centres in Thyolo district, Malawi. PARTICIPANTS: Ten health centres participated, 5 intervention (29 CHWs) and 5 control (28 CHWs). INTERVENTION: Intervention CHWs received 3 days of training in primary ear and hearing care, while among control CHWs, training was delayed for 6 months...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29020218/pan-serotype-reduction-in-progression-of-streptococcus-pneumoniae-to-otitis-media-after-rollout-of-pneumococcal-conjugate-vaccines
#6
Joseph A Lewnard, Noga Givon-Lavi, Daniel M Weinberger, Marc Lipsitch, Ron Dagan
Background: Reductions in otitis media (OM) burden following rollout of pneumococcal conjugate vaccines (PCVs) have exceeded predictions of vaccine impact. In settings with active surveillance, reductions in OM caused by vaccine-targeted pneumococcal serotypes have co-occurred with reductions in OM caused by other pathogens carried in the upper-respiratory tract of children. To understand these changes, we investigated the progression of vaccine-targeted and non-vaccine pneumococcal serotypes from carriage to OM before and after vaccine rollout...
July 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29018492/air-and-bone-conduction-frequency-specific-auditory-brainstem-response-in-children-with-agenesis-of-the-external-auditory-canal
#7
Pricila Sleifer, Dayane Domeneghini Didoné, Ísis Bicca Keppeler, Claudine Devicari Bueno, Rudimar Dos Santos Riesgo
Introduction  The tone-evoked auditory brainstem responses (tone-ABR) enable the differential diagnosis in the evaluation of children until 12 months of age, including those with external and/or middle ear malformations. The use of auditory stimuli with frequency specificity by air and bone conduction allows characterization of hearing profile. Objective  The objective of our study was to compare the results obtained in tone-ABR by air and bone conduction in children until 12 months, with agenesis of the external auditory canal...
October 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29017231/-long-term-follow-up-and-patient-satisfaction-after-tympanoplasty-with-titanium-clip-prothesis
#8
Guido Wolferts, Daniel Schicke, K-Wolfgang Delank
Aim of the present study is to evaluate the long term results of ossiculoplasty using titanium clip prosthesis. A retrospective analysis with prospective follow-up has been done including for all patients who had a Clip-PORP implanted between the years 2002-2013. Following this, audiometric hearing results were measured with clinical examination including otoscopy and quality of life evaluation using Glasgow benefit inventory. 48 patients (51 ears, 29 men, 19 women, average age 44.1 years) received followed up after an average duration of 6...
October 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28994723/middle-ear-prosthesis-with-bactericidal-efficacy-in-vitro-investigation
#9
Magdalena Ziąbka, Michał Dziadek, Elżbieta Menaszek, Rafał Banasiuk, Aleksandra Królicka
Materials used in ossicular replacement prostheses must possess appropriate biological properties, such as biocompatibility, stability, no cytotoxicity. Due to the risk of infection (otitis media and chronic otitis media), it is desirable to use an antibacterial agent for illness prevention during the ossicular reconstruction. The goal of this work was to observe biological properties of a new composite prosthesis made of ABS containing silver nanoparticles (AgNPs 45T). Samples for biological tests and then a prototype of middle ear prosthesis were prepared using injection moulding and extrusion techniques...
October 10, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28994490/computed-tomographic-findings-in-205-dogs-with-clinical-signs-compatible-with-middle-ear-disease-a-retrospective-study
#10
Audrey Belmudes, Charline Pressanti, Paul Y Barthez, Eloy Castilla-Castaño, Lionel Fabries, Marie C Cadiergues
BACKGROUND: Computed tomography (CT) is considered to be the reference method to evaluate middle ear structures. OBJECTIVES: To evaluate the presence and severity of CT changes in the middle ear and establish if any specific clinical presentations are associated with otitis media. ANIMALS: Medical records of animals referred for CT with history and clinical signs consistent with middle ear disease. METHODS: Retrospective evaluation of CT examinations of tympanic bullae performed over a six year period...
October 10, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28992726/middle-ear-histopathology-following-magnetic-delivery-to-the-cochlea-of-prednisolone-loaded-iron-oxide-nanoparticles-in-rats
#11
Jean-Francois Lafond, Mika Shimoji, Bharath Ramaswamy, Mohammed I Shukoor, Pulkit Malik, Benjamin Shapiro, Didier A Depireux
Delivery of therapy to the cochlea is a challenge and limits the efficacy of therapies meant to treat hearing loss, reverse tinnitus, and protect hearing from chemotherapy regimens. Magnetic injection is a technique that uses magnetic fields to inject nanoparticles from the middle ear into the cochlea, where they can then elute therapy to treat hearing disorders. To evaluate the safety of this treatment in the middle ear, 30 rats were subdivided into 6 groups and treated by single or multiple intratympanic injections of saline, prednisolone, nanoparticles, or nanoparticles loaded with prednisolone...
January 1, 2017: Toxicologic Pathology
https://www.readbyqxmd.com/read/28990844/impact-of-nasal-conditions-on-chronic-otitis-media-a-cross-sectional-study-in-koreans
#12
Kyung Wook Heo, Min Jae Kim, Jun Ho Lee
OBJECTIVES: We evaluated the relationship between pathological nasal conditions and pathological middle ear conditions on a large-scale epidemiological basis, conducted as a cross-sectional study at the population level using Korean National Health and Nutrition Examination Survey (KNHANES) data. STUDY DESIGN: A cross-sectional study. METHODS: In a retrospective cohort study, we analyzed data from the KNHANES (2008-2012), which used a stratified, multi-stage, probability-cluster sampling method in a rolling sampling survey of South Korean citizens...
October 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28990661/second-tympanostomy-tube-placement-in-children-with-recurrent-acute-otitis-media
#13
Phillip Huyett, Joshua J Sturm, Amber D Shaffer, Dennis J Kitsko, David H Chi
OBJECTIVES/HYPOTHESIS: To determine the rate and predictors of electing for a second bilateral myringotomy and tympanostomy tube placement (BMT) in children with recurrent acute otitis media (RAOM). STUDY DESIGN: Retrospective chart review. METHODS: Charts of 600 children who underwent BMT for RAOM between 2012 and 2014 were reviewed. RESULTS: The overall rate of a second BMT was 15.2% (91/600) and occurred a median of 1...
October 9, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28989763/into-the-dark-patterns-of-middle-ear-adaptations-in-subterranean-eulipotyphlan-mammals
#14
Daisuke Koyabu, Misato Hosojima, Hideki Endo
Evolution of the middle ear ossicles was a key innovation for mammals, enhancing the transmission of airborne sound. Radiation into various habitats from a terrestrial environment resulted in diversification of the auditory mechanisms among mammals. However, due to the paucity of phylogenetically controlled investigations, how middle ear traits have diversified with functional specialization remains unclear. In order to identify the respective patterns for various lifestyles and to gain insights into fossil forms, we employed a high-resolution tomography technique and compared the middle ear morphology of eulipotyphlan species (moles, shrews and hedgehogs), a group that has radiated into various environments, such as terrestrial, aquatic and subterranean habitats...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28988664/epidemiology-and-antimicrobial-susceptibility-of-non-typeable-haemophilus-influenzae-in-otitis-media-in-taiwanese-children
#15
Ying-Chun Cho, Nan-Chang Chiu, Fu-Yuan Huang, Daniel Tsung-Ning Huang, Lung Chang, Ching-Ying Huang, Yen-Hsin Kung, Kuo-Sheng Lee, Hsin Chi
BACKGROUND: Concerns about non-typeable Haemophilus influenzae (NTHi) in otitis media (OM) have grown after the introduction of pneumococcal conjugate vaccine (PCV). We aim to better understand the clinical role of NTHi in pediatric OM. METHODS: Middle ear fluid samples from children <18 years with OM were obtained from 2010 to 2015. For culture-positive episodes (Streptococcus pneumoniae, H. influenzae, Moraxella catarrhalis, and Streptococcus pyogenes), patients' demographic and clinical information were reviewed and analyzed...
September 18, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28988463/evidence-against-the-mucosal-traction-theory-in-cholesteatoma
#16
Henrique F Pauna, Rafael C Monsanto, Patricia Schachern, Michael M Paparella, Richard A Chole, Sebahattin Cureoglu
OBJECTIVES: To investigate the distribution of ciliated epithelium in the human middle ear and its potential role in the formation of cholesteatoma. STUDY DESIGN: Comparative human temporal bone study. METHODS: We selected temporal bones from 14 donors with a diagnosis of cholesteatoma, 15 with chronic otitis media without retraction pockets, 14 with chronic otitis media with retraction pockets, 14 with cystic fibrosis (CF), and 16 controls...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28988445/effect-of-cochlear-implantation-on-middle-ear-function-a-three-month-prospective-study
#17
Joseph D Wasson, Luke Campbell, Scott Chambers, Amy Hampson, Robert J S Briggs, Stephen J O'Leary
OBJECTIVES/HYPOTHESIS: To determine if cochlear implantation has a delayed effect on the middle ear conductive hearing mechanism by measuring laser Doppler vibrometry (LDV) of the tympanic membrane (TM) in both implanted and contralateral control ears preoperatively and 3 months postoperatively, and then comparing the relative change in LDV outcome measures between implanted and control ears. STUDY DESIGN: Prospective cohort study. METHODS: Eleven preoperative adult unilateral cochlear implant recipients in previously unoperated ears with normal anatomy and aerated temporal bones were included in this study...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28981202/novel-middle-ear-applications-for-a-synthetic-cerebrospinal-fluid-csf-sealant
#18
S Das, P A Rea
TissuePatchDural(™) is an easy to store and apply synthetic CSF sealant. Its breakdown products are naturally occurring and non-toxic. Its use appears safe in the middle ear. It is shown to successfully close mastoid CSF leaks. Its use as an adjunct in sealing middle ear fistulae is also demonstrated. This article is protected by copyright. All rights reserved.
October 5, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28980587/-atypical-inflammation-of-the-middle-ear
#19
E V Garov, A I Kryukov, V N Zelenkova, N G Sidorina, A S Kaloshina
The objective of the present study was to characterize the patients presenting with atypical inflammation of the middle ear and consider the currently available methods for their examination. A total of 20 patients at the age from 16 to 66 years were admitted to the Department of Ear Microsurgery during the period from 2008 and 2016 for the treatment of atypical inflammation of the middle ear. Eleven of them (18 ears) were found to have tuberculous lesions (TL) of the middle ear while the remaining 9 patients (11 ears) suffered giant cell vasculitis (GCV)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28978737/earless-toads-sense-low-frequencies-but-miss-the-high-notes
#20
Molly C Womack, Jakob Christensen-Dalsgaard, Luis A Coloma, Juan C Chaparro, Kim L Hoke
Sensory losses or reductions are frequently attributed to relaxed selection. However, anuran species have lost tympanic middle ears many times, despite anurans' use of acoustic communication and the benefit of middle ears for hearing airborne sound. Here we determine whether pre-existing alternative sensory pathways enable anurans lacking tympanic middle ears (termed earless anurans) to hear airborne sound as well as eared species or to better sense vibrations in the environment. We used auditory brainstem recordings to compare hearing and vibrational sensitivity among 10 species (six eared, four earless) within the Neotropical true toad family (Bufonidae)...
October 11, 2017: Proceedings. Biological Sciences
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