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https://www.readbyqxmd.com/read/28101416/light-field-otoscope-design-for-3d-in-vivo-imaging-of-the-middle-ear
#1
Noah Bedard, Timothy Shope, Alejandro Hoberman, Mary Ann Haralam, Nader Shaikh, Jelena Kovačević, Nikhil Balram, Ivana Tošić
We present a light field digital otoscope designed to measure three-dimensional shape of the tympanic membrane. This paper describes the optical and anatomical considerations we used to develop the prototype, along with the simulation and experimental measurements of vignetting, field curvature, and lateral resolution. Using an experimental evaluation procedure, we have determined depth accuracy and depth precision of our system to be 0.05-0.07 mm and 0.21-0.44 mm, respectively. To demonstrate the application of our light field otoscope, we present the first three-dimensional reconstructions of tympanic membranes in normal and otitis media conditions, acquired from children who participated in a feasibility study at the Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28101414/anti-confocal-assessment-of-middle-ear-inflammation
#2
David S Jung, John A Crowe, John P Birchall, Michael G Somekh, Chung W See
To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28096183/pneumococcal-neuraminidase-a-nana-promotes-biofilm-formation-and-synergizes-with-influenza-a-virus-in-nasal-colonization-and-middle-ear-infection
#3
John T Wren, Lance K Blevins, Bing Pang, Ankita Basu Roy, Melissa B Oliver, Jennifer L Reimche, Jessie E Wozniak, Martha A Alexander-Miller, W Edward Swords
Even in the vaccine era, Streptococcus pneumoniae (pneumococcus) remains a leading cause of otitis media, a significant public health burden, in large because of its high prevalence of nasal colonization in children. The primary pneumococcal neuraminidase NanA, which is a sialidase that catalyzes the cleavage of terminal sialic acids from host glycoconjugates, is involved in both of these processes. Coinfection with influenza A virus, which also expresses a neuraminidase, exacerbates nasal colonization and disease by S...
January 17, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28088924/microbiology-of-otitis-media-in-indigenous-australian-children-review
#4
J Jervis-Bardy, A S Carney, R Duguid, A J Leach
OBJECTIVES: To review research addressing the polymicrobial aetiology of otitis media in Indigenous Australian children in order to identify research gaps and inform best practice in effective prevention strategies and therapeutic interventions. METHODS: Literature review. RESULTS: Studies of aspirated middle-ear fluid represented a minor component of the literature reviewed. Most studies relied upon specimens from middle-ear discharge or the nasopharynx...
January 16, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28087317/acute-otitis-media-caused-by-streptococcus-pneumoniae-serotype-19a-st320-clone-epidemiological-and-clinical-characteristics
#5
Hsin Chi, Nan-Chang Chiu, Fu-Yuan Huang, Chyong-Hsin Hsu, Kuo-Sheng Lee, Li-Min Huang, Yu-Chia Hsieh
BACKGROUND: Streptococcus pneumoniae serotype 19A ST320, a highly multiresistant and virulent clone, has emerged as a common pathogen causing acute otitis media (AOM) in children. METHODS: Patients aged 0-18 years with AOM who presented at Mackay Memorial Hospital, Taipei, Taiwan were prospectively enrolled between December 1, 2009, and November 30, 2012. For each patient, a specimen of middle-ear fluid was obtained and cultured. S. pneumoniae isolates were tested by serotyping, antibiotic-resistance profiling, and multilocus sequence typing...
December 19, 2016: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28079680/middle-ear-sound-transmission-under-normal-damaged-repaired-and-reconstructed-conditions
#6
Wei Dong, Ying Tian, Xin Gao, Timothy T K Jung
HYPOTHESIS: We hypothesize that current clinical treatment strategies for the disarticulated or eroded incus have the effect of combining the incus and stapes of the human middle ear (ME) into one rigid structure, which, while capable of adequately transmitting lower-frequency sounds, fails for higher frequencies. BACKGROUND: ME damage causes conductive hearing loss (CHL) and while great progress has been made in repairing or reconstructing damaged MEs, the outcomes are often far from ideal...
January 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28069085/endoscopic-ear-surgery-a-hot-topic
#7
S Mitchell, C Coulson
OBJECTIVES: To summarise published research investigating maximal temperatures associated with endoscopes used in otology. Possible thermal issues surrounding the use of endoscopes in middle-ear surgery are discussed, and recommendations regarding the safest ways to use endoscopes in endoscopic ear surgery are made. METHODS: A non-systematic review of the relevant literature was conducted, with descriptive analysis and presentation of the results. RESULTS: There are currently no reports of any temperature-related deleterious effects in patients having undergone endoscopic ear surgery...
January 10, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28068659/hearing-loss-after-round-window-surgery-in-mice-is-due-to-middle-ear-effusion
#8
Bovey Z Zhu, Jasmine Saleh, Kevin T Isgrig, Lisa L Cunningham, Wade W Chien
BACKGROUND: Delivery of therapeutic agents directly through the round window (RW) offers promise for treating sensorineural hearing loss. However, hearing loss can result from the surgical approach itself, and the reasons for this are poorly understood. We examined the hearing loss following the 3 major steps involved with the RW approach to access the mouse cochlea: bullostomy, RW puncture, and RW injection. METHODS: Twenty-one adult CBA/J mice underwent bullostomy alone, 10 underwent RW puncture, and 8 underwent RW injection with PBS with 5% glycerol...
January 10, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28068651/comparison-of-alternative-coupling-methods-of-the-vibrant-soundbridge-floating-mass-transducer
#9
Susan Busch, Thomas Lenarz, Hannes Maier
The active middle ear implant Vibrant Soundbridge© provides a variety of coupling modalities of the floating mass transducer (FMT) to various structures of the ossicular chain and the round window. A retrospective analysis was performed on 125 subjects (n = 137 ears) (1) to compare the efficacy of the different FMT coupling modalities with increasing degree of hearing loss, (2) to compare the performance in speech outcome and the effective gain between the coupling types, and (3) to evaluate the risk of additional hearing loss of each coupling procedure...
January 10, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28065970/superficial-temporal-artery-middle-cerebral-artery-bypass-for-internal-carotid-artery-petrous-aneurysm-a-case-report
#10
Muhammad Usama Akhtar, Maqsood Akram, Tahir Mansoor Ahmed, Ahsin Manzoor Bhatti
A 13 years old boy presented with persistent ear bleed following a blow to the head. The boy was found to have a bleeding congenital aneurysm of the Petrous part of the internal carotid artery. He underwent a bypass surgery for the aneurysm and a successful Superficial Temporal Artery to Middle Cerebral Artery bypass was made.
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28061926/baro-otolagia-secondary-to-cholesteatoma
#11
Revadi Govindaraju, Meenakshi Adaikappan, Raman Rajagopalan
BACKGROUND: Baro-otalgia is a common complaint among passengers in an aircraft, in particular those who had a recent upper respiratory tract infection. The underlying pathophysiology is secondary to unequal aeration of the middle ear cleft with the surrounding atmosphere and it can be explained using Boyle's Law. We describe an unusual presentation of baro-otalgia in a pilot secondary to cholesteatoma obstructing the aditus despite normal middle ear pressure equalization provided by a grommet in the ear...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28061502/brain-abscesses-associated-with-asymptomatic-pulmonary-arteriovenous-fistulas
#12
Taek-Kyun Nam, Yong-Sook Park, Jeong-Taik Kwon
Brain abscess commonly occurs secondary to an adjacent infection (mostly in the middle ear or paranasal sinuses) or due to hematogenous spread from a distant infection or trauma. Pulmonary arteriovenous fistulas (AVFs) are abnormal direct communications between the pulmonary artery and vein. We present two cases of brain abscess associated with asymptomatic pulmonary AVF. A 65-year-old woman was admitted with a headache and cognitive impairment that aggravated 10 days prior. An magnetic resonance (MR) imaging revealed a brain abscess with severe edema in the right frontal lobe...
January 1, 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28059611/molecular-characterization-of-pneumococcal-surface-protein-k-a-potential-pneumococcal-vaccine-antigen
#13
A-Yeung Jang, Ho Seong Seo, Shunmei Lim, Gook-Hyun Chung, Han Wool Kim, Sangyong Lim, Lei Zhao, In-Ho Park, Jae Hyang Lim, Kyung-Hyo Kim
The pneumococcal capsule is indispensable for pathogenesis in systemic infections; however, many pneumococcal diseases, including conjunctivitis, otitis media, and some systemic infections in immunocompromised patients, are caused by nonencapsulated Streptococcus pneumoniae (NESp). Null capsule clade 1 (NCC1), found in group 2 NESp, expresses pneumococcal surface protein K (PspK) and is becoming prevalent among pneumococcal organisms owing to the widespread use of pneumococcal conjugate vaccines. Despite its clinical importance, the molecular mechanisms underlying the prevalence of NCC1 have not been fully elucidated...
January 6, 2017: Virulence
https://www.readbyqxmd.com/read/28059056/eaono-jos-joint-consensus-statements-on-the-definitions-classification-and-staging-of-middle-ear-cholesteatoma
#14
REVIEW
Matthew Yung, Tetsuya Tono, Ewa Olszewska, Yutaka Yamamoto, Holger Sudhoff, Masafumi Sakagami, Jef Mulder, Hiromi Kojima, Armağan İncesulu, Franco Trabalzini, Nuri Özgirgin
The European Academy of Otology and Neurotology (EAONO) has previously published a consensus document on the definitions and classification of cholesteatoma. It was based on the Delphi consensus methodology involving the broad EAONO membership. At the same time, the Japanese Otological Society (JOS) had been working independently on the "Classification and Staging of Cholesteatoma." EAONO and JOS then decided to collaborate and produce a joint consensus document. The EAONO/JOS joint consensus on "Definitions, Classification and Staging of Middle Ear Cholesteatoma" was formally presented at the 10th International Conference on Cholesteatoma and Ear Surgery in Edinburgh, June 5-8, 2016...
6, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28056134/middle-ear-mass-causing-vertigo-and-facial-nerve-weakness
#15
Aron Kandinov, Matthew Smith, Syed F Ahsan
No abstract text is available yet for this article.
January 5, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28052264/a-retrospective-multicentre-cohort-review-of-patient-characteristics-and-surgical-aspects-versus-the-long-term-outcomes-for-recipients-of-a-fully-implantable-active-middle-ear-implant
#16
Philippe P Lefebvre, Javier Gisbert, Domenico Cuda, Stéphane Tringali, Arnaud Deveze
OBJECTIVE: To summarise treatment outcomes compared to surgical and patient variables for a multicentre recipient cohort using a fully implantable active middle ear implant for hearing impairment. To describe the authors' preferred surgical technique to determine microphone placement. STUDY DESIGN: Multicentre retrospective, observational survey. SETTING: Five tertiary referral centres. PATIENTS: Carina recipients (66 ears, 62 subjects) using the current Cochlear® Carina® System or the legacy device, the Otologics® Fully Implantable Middle Ear, with a T2 transducer...
January 5, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28050213/auditory-alterations-in-children-infected-by-human-immunodeficiency-virus-verified-through-auditory-processing-test
#17
Ana Carla Leite Romero, Lívia Marangoni Alfaya, Alina Sanches Gonçales, Ana Claudia Figueiredo Frizzo, Myriam de Lima Isaac
Introduction The auditory system of HIV-positive children may have deficits at various levels, such as the high incidence of problems in the middle ear that can cause hearing loss. Objective The objective of this study is to characterize the development of children infected by the Human Immunodeficiency Virus (HIV) in the Simplified Auditory Processing Test (SAPT) and the Staggered Spondaic Word Test. Methods We performed behavioral tests composed of the Simplified Auditory Processing Test and the Portuguese version of the Staggered Spondaic Word Test (SSW)...
January 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28050207/is-there-a-system%C3%A4-c-inflammatory-effect-of-cholesteatoma
#18
M Mustafa Kılıçkaya, Giray Aynali, Mustafa Tuz, Özkan Bagcı
Introduction Inflammation causes squamous epithelial transformation of the mucosa in the middle ear cavity and plays a role in the onset, growth, spread, and recurrence of cholesteatoma. Objectives The objective of this study is to investigate the systemic inflammatory effect in chronic otitis with cholesteatoma. Methods The study included a total of 311 patients comprising 156 patients with a pathology diagnosis of cholesteatoma and a control group of 155 with no active inflammation. The Neutrophil-to-lymphocyte Ratio (NLR) was calculated by dividing the neutrophil value by the lymphocyte value...
January 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28045835/normative-wideband-reflectance-equivalent-admittance-at-the-tympanic-membrane-and-acoustic-stapedius-reflex-threshold-in-adults
#19
M Patrick Feeney, Douglas H Keefe, Lisa L Hunter, Denis F Fitzpatrick, Angela C Garinis, Daniel B Putterman, Garnett P McMillan
OBJECTIVES: Wideband acoustic immittance (WAI) measures such as pressure reflectance, parameterized by absorbance and group delay, equivalent admittance at the tympanic membrane (TM), and acoustic stapedius reflex threshold (ASRT) describe middle ear function across a wide frequency range, compared with traditional tests employing a single frequency. The objective of this study was to obtain normative data using these tests for a group of normal-hearing adults and investigate test-retest reliability using a longitudinal design...
December 30, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/28038780/solitary-neurofibroma-of-the-jugular-foramen-with-extension-to-the-middle-ear-case-report
#20
M Carrillo García, A Pons Escoda
No abstract text is available yet for this article.
December 27, 2016: Radiología
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