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https://www.readbyqxmd.com/read/29474258/etiology-of-acute-otitis-media-and-characterization-of-pneumococcal-isolates-after-introduction-of-13-valent-pneumococcal-conjugate-vaccine-in-japanese-children
#1
Kimiko Ubukata, Miyuki Morozumi, Megumi Sakuma, Misako Takata, Eriko Mokuno, Takeshi Tajima, Satoshi Iwata
BACKGROUND: Acute otitis media (AOM) is a leading cause of childhood morbidity and antibiotic prescriptions. We examined etiologic changes in AOM after introduction of 13-valent pneumococcal conjugate vaccine as routine immunization for Japanese children in 2014. Serotypes, resistance genotypes, antibiotic susceptibilities, and multilocus sequence typing of pneumococcal isolates were also characterized. METHODS: Otolaryngologists prospectively collected middle ear fluid from 582 children by tympanocentesis or sampling through a spontaneously ruptured tympanic membrane between June 2016 and January 2017...
February 22, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29472067/neurophysiology-of-hearing-in-patients-with-mucopolysaccharidosis-type-iv
#2
Kyoko Nagao, Thierry Morlet, Elizabeth Haley, Jennifer Padilla, Julianne Nemith, Robert W Mason, Shunji Tomatsu
BACKGROUND: Hearing impairment is a common problem in patients with mucopolysaccharidosis IV (MPS IV) throughout their life. Many of the adult patients with MPS IV exhibit permanent or severe hearing loss. However, there has been no systematic review of detailed audiological test results in MPS IV. MATERIALS AND METHODS: Fourteen individuals with MPS IV (13 MPS IVA and 1 MPS IVB; aged between 12 and 38 years old) participated in the current study. We obtained auditory neurophysiological responses (auditory brainstem responses and otoacoustic emissions test) in addition to pure-tone audiometry and middle ear function tests (tympanometry and acoustic reflexes)...
February 8, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29467266/oldest-known-multituberculate-stapes-suggests-an-asymmetric-bicrural-pattern-as-ancestral-for-multituberculata
#3
Julia A Schultz, Irina Ruf, Thomas Martin
Middle ear ossicles (malleus, incus, stapes) are known for few multituberculate taxa, and three different stapedial morphotypes have been suggested: (i) slender, columelliform and microperforate, (ii) robust and rod-like, and (iii) bicrural. Reinvestigation of Upper Jurassic (Kimmeridgian) mammalian petrosals from the Guimarota coal mine in central Portugal (Western Europe) revealed an asymmetric bicrural stapes (ABS) in the paulchoffatiid Pseudobolodon oreas The middle ear ossicles displaced inside the osseous vestibule were detected by a µCT analysis...
February 28, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29466040/determination-of-anatomic-landmarks-for-optimal-placement-in-captive-bolt-euthanasia-of-goats
#4
Paul J Plummer, Jan K Shearer, Katie E Kleinhenz, Leslie C Shearer
OBJECTIVE To determine the optimal anatomic site and directional aim of a penetrating captive bolt (PCB) for euthanasia of goats. SAMPLE 8 skulls from horned and polled goat cadavers and 10 anesthetized horned and polled goats scheduled to be euthanized at the end of a teaching laboratory. PROCEDURES Sagittal sections of cadaver skulls from 8 horned and polled goats were used to determine the ideal anatomic site and aiming of a PCB to maximize damage to the midbrain region of the brainstem for euthanasia. Anatomic sites for ideal placement and directional aiming were confirmed by use of 10 anesthetized horned and polled goats...
March 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29460823/effect-of-body-mass-index-on-middle-ear-resonance-frequency
#5
Miray Sözen, Işılay Öz, Selim Erbek
OBJECTIVE: Multifrequency tympanometry (MFT) analyzes tympanograms obtained using different probe tones between 226 and 2000 Hz. An important parameter of MFT is resonance frequency (RF). Studies have recently demonstrated that the RF value can vary depending on many factors. To provide new data regarding MFT, middle ear RF values were investigated with regard to body mass index (BMI). MATERIALS AND METHODS: This study included 78 volunteers (i.e., 156 ears) aged 18-40 years who did not have hearing loss and whose otoscopic examinations were normal...
February 20, 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29460543/anatomic-relationship-between-temporomandibular-joint-and-middle-ear
#6
L Ottria, D Lauritano, F Guzzo, M Gargari, A Barlattani
The present study was designed to identify a relationship between temporomandibular joint and tympanic cavity and potentially justify the possible clinical correlations between these two anatomical entities. For this reason the authors conducted an anatomic-pathological study about the temporomandibular joint (TMJ) and the neighboring anatomical areas of the middle ear by autopsy finds of human adults.
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29460094/ear-nose-and-throat-involvement-in-granulomatosis-with-polyangiitis-how-it-presents-and-how-it-determines-disease-severity-and-long-term-outcomes
#7
Mara Felicetti, Diego Cazzador, Roberto Padoan, Alfonso Luca Pendolino, Chiara Faccioli, Ennio Nardello, Alvise Berti, Marina Silvestrini, Giuseppe Paolazzi, Giuliano Brunori, Elisabetta Zanoletti, Enzo Emanuelli, Alessandro Martini, Franco Schiavon
Ear, nose and throat (ENT) manifestations in granulomatosis with polyangiitis (GPA) represent the most frequent symptoms at disease onset. The aim of the study was to analyse ENT involvement at diagnosis, as well as how it could influence relapse rate, mortality and disease severity. A retrospective non-controlled cohort study was performed including all consecutive diagnosed GPA from 1996 to 2016 in two rheumatology centres of Northern Italy, focusing particularly on ENT presenting signs and symptoms at baseline...
February 20, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29459069/otorhinolaryngology-surgery-analysis-in-japan-and-thailand-comparing-nihon-university-school-of-medicine-with-thammasat-university-faculty-of-medicine
#8
Yasuyuki Nomura, Teruo Toi, Waipoj Chanvimalueng, Prakitpunthu Tomtitchong, Warunya Weerarattanakul, Maki Jike, Hirotaka Tomomatsu, Kazunori Kawasaki, Wipakorn Chayopong Kawasaki, Eric Hajime Jego, Takeshi Oshima, Preecha Wanichsetakul
BACKGROUND/OBJECTIVE: We compared the surgery data of the department of otorhinolaryngology of the university hospitals in Japan and Thailand to make each feature and the differences of both otorhinolaryngology surgeries clear. There are some medical meetings and congresses between Japan and Thailand, but so far it has not reported about the comparison of surgery data. METHODS: Retrospectively, we analyzed the surgical statistics of department of otorhinolaryngology of Nihon University Itabashi Hospital (Japan) and Thammasat University Hospital (Thailand) between 2013 and 2014...
February 17, 2018: Asian Journal of Surgery
https://www.readbyqxmd.com/read/29458340/a-microbiome-case-control-study-of-recurrent-acute-otitis-media-identified-potentially-protective-bacterial-genera
#9
Rachael Lappan, Kara Imbrogno, Chisha Sikazwe, Denise Anderson, Danny Mok, Harvey Coates, Shyan Vijayasekaran, Paul Bumbak, Christopher C Blyth, Sarra E Jamieson, Christopher S Peacock
BACKGROUND: Recurrent acute otitis media (rAOM, recurrent ear infection) is a common childhood disease caused by bacteria termed otopathogens, for which current treatments have limited effectiveness. Generic probiotic therapies have shown promise, but seem to lack specificity. We hypothesised that healthy children with no history of AOM carry protective commensal bacteria that could be translated into a specific probiotic therapy to break the cycle of re-infection. We characterised the nasopharyngeal microbiome of these children (controls) in comparison to children with rAOM (cases) to identify potentially protective bacteria...
February 20, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29458274/nutrient-composition-ruminal-degradability-and-whole-tract-digestibility-of-whole-crop-maize-silage-from-nine-current-varieties
#10
Leonhard Gruber, Georg Terler, Wilhelm Knaus
Since maize silage is an important forage in cattle nutrition, it is important to know its nutritive value. Much effort is put into breeding maize, and several new varieties are introduced on the market every year. This requires periodical analyses of the nutritive value of current maize varieties for the formulation of cattle rations. The aim of this study was to examine the nutritive value of whole crop maize silage (WCMS) from nine maize varieties in 3 consecutive years. For the analysis of nutrient composition and ruminal degradability of organic matter (OM), crude protein (CP), neutral detergent fibre (aNDFom) and non-fibre carbohydrates (NFC), varieties were harvested at three harvest dates (50%, 55% and 60% dry matter content in ear)...
April 2018: Archives of Animal Nutrition
https://www.readbyqxmd.com/read/29456948/is-routine-use-of-high-resolution-computerized-tomography-of-temporal-bone-in-patients-of-atticoantral-chronic-suppurative-otitis-media-without-intracranial-complications-justified
#11
Meeta Bathla, Hiren Doshi, Atul Kansara
Role of high resolution computerized tomography (HRCT) of temporal bone is established in cases of atticoantral chronic suppurative otitis media (CSOM) with intracranial complications. Routine use of HRCT in management of patients of atticoantral CSOM without intracranial complications has been an issue of debate. The aim of this study was to evaluate the routine use of HRCT of temporal bone in such cases. This study was a prospective study done at LG hospital, AMC MET Medical College, Ahmedabad to evaluate and compare the temporal bone findings in HRCT and intraoperative findings in 100 patients with atticoantral CSOM...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456946/detection-of-epstein-barr-and-human-papilloma-viruses-in-the-middle-ear-squamous-cell-carcinoma
#12
Agus Surono, Bambang Hariwiyanto, Edhie Samodra
The uncommon ear tumor of middle ear squamous cell carcinoma (MESCC) is thought to be associated with the history of long-term chronic otitis media in the most cases. The main etiologic factor of MESCC is still unclear and may be multifactorial. Infections of Epstein-Barr virus (EBV) and Human Papillomavirus (HPV) are considered as one of the etiologic factor of MESCC. Previous studies have shown that the EBV and HPV have been detected in MESCC. Although the EBV and HPV have been implicated in human malignancies, their roles in pathogenesis of MESCC have not been elucidated...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456937/to-evaluate-and-compare-the-result-of-ossiculoplasty-using-different-types-of-graft-materials-and-prosthesis-in-cases-of-ossicular-discontinuity-in-chronic-suppurative-otitis-media-cases
#13
Suresh Kumar, Kanak Yadav, Tarun Ojha, Abhishek Sharma, Amit Singhal, Saurabh Gakhar
Chronic suppurative otitis media, with and without cholesteatoma, frequently results in disruption of the ossicular chain. The present study was designed to compare the outcome using autologous ossicle and titanium prosthesis in two groups of suitable patients presenting with chronic suppurative otitis media for middle ear reconstructive surgeries. A prospective study done from July 2012 to December 2013, at Mahatma Gandhi Medical College and Hospital, Sitapura, Jaipur (Rajasthan). The target group included patients with chronic suppurative otitis media admitted and planned for reconstructive middle ear surgery...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29455623/rare-case-of-bilateral-aural-atresia-and-cochlear-dysplasia-when-cochlear-implantation-is-not-the-answer
#14
Maja Svrakic
OBJECTIVE AND IMPORTANCE: Reports of patients with concurrent middle and inner ear anomalies are rare. These patients present a surgical challenge for cochlear implantation. The surgical risk must be weighed against the predicted benefit of the patient's hearing outcome and subsequent development of speech and language as well as their quality of life. CLINICAL PRESENTATION: Thirteen-year-old boy presented to the Otology clinic for auditory rehabilitation options...
February 17, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29454371/auditory-effects-of-autologous-fat-graft-for-torp-stabilization-in-the-middle-ear-a-cadaveric-study
#15
Margaret Aron, Thomas G Landry, Manohar Bance
BACKGROUND: Total ossicular replacement prostheses (TORP) are often used to re-establish ossicular coupling of sound in an ear lacking a stapes supra-structure. The use of TORPs, however, is associated with a 2/3 five year failure rate due to their anatomic instability over time in the middle ear. The use of autologous fat to try and stabilize TORPs may improve long-term results with this challenging ossicular reconstruction technique. METHODS: A cadaveric temporal bone model was developed and laser Doppler vibrometry was used to measure and record round window membrane vibration in response to sound stimulation under the following conditions: normal middle ear, middle ear filled with fat, normal middle ear with TORP prosthesis, TORP prosthesis with fat around its distal end and TORP prosthesis with fat filling the middle ear...
February 17, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29450472/otorhinolaryngology-and-diving-part-1-otorhinolaryngological-hazards-related-to-compressed-gas-scuba-diving-a-review
#16
Matt Lechner, Liam Sutton, Jonathan M Fishman, David M Kaylie, Richard E Moon, Liam Masterson, Christoph Klingmann, Martin A Birchall, Valerie J Lund, John S Rubin
Importance: Scuba diving is becoming increasingly popular. However, scuba diving is associated with specific risks; 80% of adults and 85% of juvenile divers (aged 6-17 years) have been reputed to have an ear, nose, or throat complaint related to diving at some point during their diving career. Divers frequently seek advice from primary care physicians, diving physicians, and otorhinolaryngologists, not only in the acute setting, but also related to the long-term effects of diving. Observations: The principles underpinning diving-related injuries that may present to the otorhinolaryngologist rely on gas volume and gas saturation laws, and the prevention of these injuries requires both that the diver is skilled and that their anatomy allows for pressure equalization between the various anatomical compartments...
February 15, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29450387/orbital-cellulitis-and-brain-abscess-rare-complications-of-maxillo-spheno-ethmoidal-rhinosinusitis
#17
Farah Constantin, Patricia-Alexandra Niculescu, Oana Petre, Daniel Balasa, Alexandru Tunas, Ioana Rusu, Mihai Lupascu, Cristiana Orodel
Sinus infections can be complicated by ocular infections and, in late phases, by brain parenchyma infection. The article debates the case of a 12-year-old patient suffering from paucisymptomatic maxillo-spheno-ethmoidal rhinosinusitis, which was later complicated by orbital cellulitis, ending with the development of a brain abscess. The treatment is complex, initially targeting the source of the infection through draining the collection by middle maxillary antrostomy and anterior posterior ethmoidectomy, then the ablation of the brain abscess and postoperatively with prolonged massive antibiotherapy...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29449589/loss-of-the-homeostatic-protein-bpifa1-leads-to-exacerbation-of-otitis-media-severity-in-the-junbo-mouse-model
#18
Apoorva Mulay, Derek W Hood, Debbie Williams, Catherine Russell, Steve D M Brown, Lynne Bingle, Michael Cheeseman, Colin D Bingle
Otitis Media (OM) is characterized by epithelial abnormalities and defects in innate immunity in the middle ear (ME). Although, BPIFA1, a member of the BPI fold containing family of putative innate defence proteins is abundantly expressed by the ME epithelium and SNPs in Bpifa1 have been associated with OM susceptibility, its role in the ME is not well characterized. We investigated the role of BPIFA1 in protection of the ME and the development of OM using murine models. Loss of Bpifa1 did not lead to OM development...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29449102/anterosuperior-anchoring-myringoplasty-using-cyanoacrylate-glue-can-prevent-packing-gelfoam-in-the-middle-ear-cavity
#19
Y Li, J Liang, Y Cheng, Q Zhang, X Ren, Y Sheng
OBJECTIVES: Although a number of methods have been attempted to improve securing the graft, packing gelfoam in the middle ear cavity cannot be avoided, which could obstruct the tympanic ostium of the Eustachian tube and affect inner ear function. Myringoplasty using tissue adhesive has gained traction because tissue adhesives can effectively stabilise the graft and act as scaffolding to improve the graft uptake. The aim of this prospective study was to explore myringoplasty using cyanoacrylate glue with no packing in the middle ear cavity for the repair of subtotal tympanic membrane (TM) perforations...
February 12, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29447884/knowledge-and-attitudes-of-early-childhood-development-practitioners-towards-hearing-health-in-poor-communities
#20
Shouneez Yousuf Hussein, De Wet Swanepoel, Leigh Biagio de Jager, Faheema Mahomed-Asmail
OBJECTIVE: Within the educational sector of low-and middle-income countries (LMICs), formal and informal early childhood development (ECD) centers are often the first point of contact for majority of children. Since early hearing detection services are mostly absent in LMICs, these ECD centers may serve as the first point of access to screenings for these children. ECD practitioner awareness regarding hearing and hearing loss is essential for the successful implementation of hearing screening programs...
March 2018: International Journal of Pediatric Otorhinolaryngology
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