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https://www.readbyqxmd.com/read/28431515/the-effectiveness-of-creating-an-online-life-story-book-on-persons-with-early-dementia-and-their-informal-caregivers-a-protocol-of-a-randomized-controlled-trial
#1
Teuntje R Elfrink, Sytse U Zuidema, Miriam Kunz, Gerben J Westerhof
BACKGROUND: Dementia has a high burden for patients, informal caregivers and society. Given changes in care systems, more persons with dementia will live longer at home. However, living at home (with dementia) with a good quality of life is not easy to achieve. Dementia is often accompanied by neuropsychiatric symptoms like apathy, agitation, depression, and anxiety, which have a negative impact on quality of life. Whereas cognitive deterioration can hardly be influenced, it is possible to reduce neuropsychiatric symptoms...
April 21, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28409050/correlation-of-mri-visual-scales-with-neuropsychological-profile-in-mild-cognitive-impairment-of-parkinson-s-disease
#2
Luiz Felipe Vasconcellos, João Santos Pereira, Marcelo Adachi, Denise Greca, Manuela Cruz, Ana Lara Malak, Helenice Charchat-Fichman, Mariana Spitz
Few studies have evaluated magnetic resonance imaging (MRI) visual scales in Parkinson's disease-Mild Cognitive Impairment (PD-MCI). We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Global Cortical Atrophy (GCA), Fazekas, and medial temporal atrophy (MTA). The analysis revealed that both PD groups (amnestic and nonamnestic) showed worse performance on several tests when compared to CO. Memory, executive function, and attention impairment were more severe in amnestic PD-MCI group...
2017: Parkinson's Disease
https://www.readbyqxmd.com/read/28400371/retinal-microvascular-network-geometry-and-cognitive-abilities-in-community-dwelling-older-people-the-lothian-birth-cohort-1936-study
#3
Sarah McGrory, Adele M Taylor, Mirna Kirin, Janie Corley, Alison Pattie, Simon R Cox, Baljean Dhillon, Joanna M Wardlaw, Fergus N Doubal, John M Starr, Emanuele Trucco, Thomas J MacGillivray, Ian J Deary
AIM: To examine the relationship between retinal vascular morphology and cognitive abilities in a narrow-age cohort of community-dwelling older people. METHODS: Digital retinal images taken at age ∼73 years from 683 participants of the Lothian Birth Cohort 1936 (LBC1936) were analysed with Singapore I Vessel Assessment (SIVA) software. Multiple regression models were applied to determine cross-sectional associations between retinal vascular parameters and general cognitive ability (g), memory, processing speed, visuospatial ability, crystallised cognitive ability and change in IQ from childhood to older age...
October 17, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28380705/the-effects-of-integrated-attention-training-for-older-chinese-adults-with-subjective-cognitive-complaints
#4
Calvin Pak-Wing Cheng, Linda Chiu-Wa Lam, Sheung-Tak Cheng
OBJECTIVE: Early intervention to reduce cognitive decline and preserve functioning is a compelling public health issue. Because impaired attention occurs early in the process of cognitive impairment, focusing training strategies upon attention may be a potential intervention to prevent further cognitive decline. We sought to test the effects on cognitive performance and daily functioning of a new cognitive training program that focuses on attention. METHOD: This single-blind randomized controlled trial lasted 6 months and included two phases...
December 1, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28328492/digital-tracking-of-cognitive-decline-researchers-are-co-opting-computers-in-their-efforts-to-detect-early-signs-of-dementia
#5
Michele Solis
Pinpointing where healthy brain aging leaves off and dementia begins is difficult. Is a slip in memory an expected outcome for a too-busy person or a warning of something else? If an empty-nester loses the motivation to cook, is it a sign that the person is enjoying retirement after a lifetime spent cooking or an early sign of a cognitive decline?
March 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28304305/combined-dual-task-gait-training-and%C3%A2-aerobic-exercise-to-improve-cognition-%C3%A2-mobility-and%C3%A2-vascular-health-in%C3%A2-community-dwelling-older-adults-at%C3%A2-risk-for-future-cognitive-decline1
#6
Michael A Gregory, Narlon C Boa Sorte Silva, Dawn P Gill, Cheri L McGowan, Teresa Liu-Ambrose, J Kevin Shoemaker, Vladimir Hachinski, Jeff Holmes, Robert J Petrella
This 6-month experimental case series study investigated the effects of a dual-task gait training and aerobic exercise intervention on cognition, mobility, and cardiovascular health in community-dwelling older adults without dementia. Participants exercised 40 min/day, 3 days/week for 26 weeks on a Biodex GaitTrainer2 treadmill. Participants were assessed at baseline (V0), interim (V1: 12-weeks), intervention endpoint (V2: 26-weeks), and study endpoint (V3: 52-weeks). The study outcomes included: cognition [executive function (EF), processing speed, verbal fluency, and memory]; mobility: usual & dual-task gait (speed, step length, and stride time variability); and vascular health: ambulatory blood pressure, carotid arterial compliance, and intima-media thickness (cIMT)...
March 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28290247/modulation-of-retinal-arteriolar-central-reflection-by-apoe-genotype
#7
Shaun Frost, Alauddin Bhuiyan, David Offerman, James D Doecke, S Lance Macaulay, Hamid R Sohrabi, David Ames, Colin Masters, Ralph N Martins, Yogesan Kanagasingam, Aibl Research Group
This study investigated the retinal arteriolar central reflex (CR, the central reflection observed in photographs of retinal vessels), which may provide information about micro-vascular health in the retina and also the brain, due to the homology between these vascular networks. The study also describes a novel computer based semi-automated technique that accurately quantifies retinal arteriolar CR and vessel width, and calculates the CR to vessel width ratio (CRR) from digital retinal photographs. Digital retinal photographs were collected from participants in the Australian Imaging, Biomarkers and Lifestyle study of ageing (AIBL), including 25 participants diagnosed with Alzheimer's disease (AD) (age 72...
March 9, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28284872/cognitive-functioning-of-individuals-aged-90-years-and-older-without-dementia-a-systematic-review
#8
REVIEW
N Legdeur, T T Binnekade, R H Otten, M Badissi, P Scheltens, P J Visser, A B Maier
INTRODUCTION: Reference values to define cognitive impairment in individuals aged 90 years and older are lacking. We systematically reviewed the literature to determine the level of cognitive functioning of individuals aged 90 years and older without dementia. METHODS: The search identified 3972 articles of which 20 articles were included in the review. We calculated mean cognitive test scores and cut-off scores for cognitive tests published in two or more articles...
March 8, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28276862/excessive-decline-from-premorbid-functioning-detecting-performance-invalidity-with-the-wais-iv-and-demographic-predictions
#9
Phillip K Martin, Ben P Hunter, Amanda M Rach, Robin J Heinrichs, Ryan W Schroeder
OBJECTIVE: Excessive Decline from Premorbid Functioning (EDPF) is presented as a construct and defined as a discrepancy between predicted premorbid ability and current test performance that is so atypical of individuals with true neurocognitive impairment that it is likely the product of performance invalidity. New embedded PVTs (EDPF-FSIQ, EDPF-VW, and EDPF-PP) were derived by comparing scores from the WAIS-IV to TOPF demographically predicted premorbid estimates and then examined for classification accuracy...
February 17, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28276861/screening-for-dementia-in-arabic-normative-data-from-an-elderly-lebanese-sample
#10
Fadi Abou-Mrad, Gordon Chelune, Edward Zamrini, Lubna Tarabey, Maryse Hayek, Patricia Fadel
OBJECTIVE: Prevention and treatment of dementia is a global concern that requires involvement of international samples. The purpose of this study is to develop culturally sensitive norms based on normal older Lebanese adults using multiple cognitive screening measures translated into Arabic for regional use. METHODS: Participants were 164 community dwelling older Lebanese adults without cognitive complaints. They were administered the following cognitive measures in Arabic: Alzheimer's Disease 8-item questionnaire, Montreal Cognitive Assessment, Mini Mental Status Exam, Modified Mini Mental Status, Brief Visuospatial Memory Test-Revised, Lebanese Digit Span, Cross-Linguistic Naming Test, and phonemic and semantic fluency tests...
February 23, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28167237/does-high-dose-vitamin-d-supplementation-enhance-cognition-a-randomized-trial-in-healthy-adults
#11
Jacqueline A Pettersen
BACKGROUND: Insufficiency of 25-hydroxyvitamin D [25(OH)D] has been associated with dementia and cognitive decline. However, the effects of vitamin D supplementation on cognition are unclear. It was hypothesized that high dose vitamin D3 supplementation would result in enhanced cognitive functioning, particularly among adults whose 25(OH)D levels were insufficient (<75nmol/L) at baseline. METHODS: Healthy adults (n=82) from northern British Columbia, Canada (54° north latitude) with baseline 25(OH)D levels ≤100nmol/L were randomized and blinded to High Dose (4000IU/d) versus Low Dose (400IU/d) vitamin D3 (cholecalciferol) for 18weeks...
April 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28161989/-it-brings-it-all-back-all-those-good-times-it-makes-me-go-close-to-tears-creating-digital-personalised-stories-with-people-who-have-dementia
#12
Valerie Critten, Natalia Kucirkova
The purpose of these three case studies was to analyse and theoretically explain the contribution of digital multimedia personalisation to stimulate and share long-term memories of people who live with mild to moderate dementia. We investigated how the use of a freely available iPad app can, in a supporting context, facilitate the creation of personalised multimedia stories, including the participants' audio recordings, texts and photos of items, places or people important to them. Three people who were recruited from a club for people living with dementia created personalised multimedia stories using their own photographs and/or pictures downloaded from the internet, with written captions and audio-recorded voiceovers...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28160181/determinants-of-employment-in-people-living-with-hiv-in-the-netherlands
#13
Marlies N Wagener, Lennert van den Dries, Job Van Exel, Harald S Miedema, Eric C M van Gorp, Pepijn D D M Roelofs
Objectives Since HIV has become a manageable chronic disease, employment is of increasing importance for people living with HIV (PLWH). This study aimed to investigate the level of work participation among PLWH in the Netherlands, and the associated determinants of employment. Methods For this study the baseline measurements of a longitudinal cohort study with a 2-year follow-up, the TREVI project, were used. The TREVI project aims to study cognitive function disorders among PLWH in relation to their employment, productivity, and social functioning...
February 3, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28068866/cognitive-abnormalities-and-cerebral-perfusion-defects-in-a-community-dwelling-cohort-of-elderly-men-with-mmse-within-the-normal-range
#14
Lena André-Petersson, Ola Thorsson, Arkadiusz Siennicki-Lantz
OBJECTIVES: Mini Mental State Examination's (MMSE's) sensitivity in its upper level is questioned, hence we investigated cognitive abnormalities and defects in regional cerebral blood flow (rCBF) in elderly with MMSE scores ≥24. METHODS: One hundred and four men at age 81 with MMSE scores ≥24 (mean 28.4 ± 1.7), no dementia or stroke, were examined with neuropsychological test battery, and their rCBF was estimated using (99mTc)-HMPAO SPECT. RESULTS: MMSE was very sparsely correlated with rCBF...
January 9, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28026197/what-paint-can-tell-us-a-fractal-analysis-of-neurological-changes-in-seven-artists
#15
Alex Forsythe, Tamsin Williams, Ronan G Reilly
OBJECTIVE: The notion that artistic capability increases with dementia is both novel and largely unsupported by available literature. Recent research has suggested an emergence of artistic capabilities to be a by-product of involuntary behaviour seen with dementia, as opposed to a progression in original thinking (de Souza, et al., 2010). A far more complementary explanation comes from Hannemann (2006), who suggests that art offers an outlet for dementia patients to refine and sharpen their cognitive abilities...
January 2017: Neuropsychology
https://www.readbyqxmd.com/read/28005562/neuropsychological-testing-in-pathologically-verified-alzheimer-disease-and-frontotemporal-dementia-how-well-do-the-uniform-data-set-measures-differentiate-between-diseases
#16
Aaron R Ritter, Gabriel C Leger, Justin B Miller, Sarah J Banks
BACKGROUND/AIMS: Differences in cognition between frontotemporal dementia (FTD) and Alzheimer disease (AD) are well described in clinical cohorts, but have rarely been confirmed in studies with pathologic verification. For emerging therapeutics to succeed, determining underlying pathology early in the disease course is increasingly important. Neuropsychological evaluation is an important component of the diagnostic workup for AD and FTD. Patients with FTD are thought to have greater deficits in language and executive function while patients with AD are more likely to have deficits in memory...
December 21, 2016: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/27941404/dichotic-digits-test-performance-across-the-ages-results-from-two-large-epidemiologic-cohort-studies
#17
Mary E Fischer, Karen J Cruickshanks, David M Nondahl, Barbara E K Klein, Ronald Klein, James S Pankow, Ted S Tweed, Dayna S Dalton, Adam J Paulsen
OBJECTIVES: The Dichotic Digits test (DDT) has been widely used to assess central auditory processing but there is limited information on observed DDT performance in a general population. The purpose of the study was to determine factors related to DDT performance in a large cohort spanning the adult age range. DESIGN: The study was cross-sectional and subjects were participants in the Epidemiology of Hearing Loss Study (EHLS), a population-based investigation of age-related hearing loss, or the Beaver Dam Offspring Study (BOSS), a study of aging in the adult offspring of the EHLS members...
December 7, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/27928511/latino-hispanic-alzheimer-s-caregivers-experiencing-dementia-related-dressing-issues-corroboration-of-the-preservation-of-self-model-and-reactions-to-a-smart-dresser-computer-based-dressing-aid
#18
Diane Feeney Mahoney, David W Coon, Cecil Lozano
OBJECTIVE: To gain an understanding of Latino/Hispanic caregivers' dementia-related dressing issues, their impressions of using a "smart" context-aware dresser to coach dressing, and recommendations to improve its acceptability. METHOD: The same Latina moderator conducted all the caregiver focus groups. She followed a semi-structured interview guide that was previously used with White and African American family caregivers who experienced Alzheimer's disease related dressing challenges...
November 2016: Digital Health
https://www.readbyqxmd.com/read/27882654/digital-technologies-as-truth-bearers-in-health-care
#19
Ruth Bartlett, Andrew Balmer, Petula Brannelly
In this paper, we explore the idea of digital technologies as truth-bearers in health care and argue that devices like SenseCam, which facilitate reflection and memory recall, have a potentially vital role in healthcare situations when questions of veracity are at stake (e.g., when best interest decisions are being made). We discuss the role of digital technologies as truth-bearers in the context of nursing people with dementia, as this is one area of health care in which the topic of truth-telling has been hotly debated...
January 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/27878426/the-differential-effects-of-alzheimer-s-disease-and-lewy-body-pathology-on-cognitive-performance-a-meta-analysis
#20
REVIEW
Ashita S Gurnani, Brandon E Gavett
Differential diagnosis of Alzheimer's disease (AD) from normal aging and other dementia etiologies is imperative for disease specific treatment options and long-term care planning. Neuropathological confirmation is the gold standard for neurodegenerative disease diagnosis, yet most published studies examining the use of neuropsychological tests in the differential diagnosis of dementia rely upon clinical diagnostic outcomes. The present study undertook a meta-analytic review of the literature to identify cognitive tests and domains that allow for the differentiation of individuals with AD pathology from individuals with dementia with Lewy Bodies (DLB) pathology and pathology-free individuals...
March 2017: Neuropsychology Review
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