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The first International Association of Diabetes and Pregnancy Study Groups Summit on the diagnosis of gestational diabetes in early pregnancy (Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) Summit) was held on the 17 November 2022 in Sydney, Australia. It sought to use the TOBOGM trial findings to scope the issues involved with early screening, to inform future discussions over possible approaches for diagnosing gestational diabetes mellitus (GDM) in early pregnancy. Most delegates supported testing for early GDM using a one-step 75 g oral glucose tolerance test approach with Canadian Diabetes Association criteria preferred, but highlighted the importance of considering resources, cost, consumer perspectives and equity in translating TOBOGM results into a clinical approach to screening for, and diagnosing, early GDM...

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Social media is currently abuzz with discussions about the topic of women's gamophobia in China. Nevertheless, there is few research investigating gamophobia from a psychological perspective. This study utilizes content analysis and sentiment analysis to examine and analyze 879 individuals' texts about gamophobia on Little Red Book and uses psychoanalytic theory, which is centered on comprehending and interpreting the psychological processes of the human mind, to investigate the elements that contribute to women's gamophobia, aiming to address this knowledge gap...

OBJECTIVES: The objective of this study was to explore experiences and needs of parents visiting critically ill family members in intensive care units (ICUs) accompanied by their underaged children (<18 years). METHODS: Six semistructured interviews with parents were conducted in a qualitative design. Data analysis and synthesis were performed using Braun and Clarke's thematic analysis. This study was conducted in five adult ICUs in Switzerland. FINDINGS: Parents opted for early and truthful involvement of their children, and the majority initiated the visits themselves...

PURPOSE: Knowledge of neurovascular anatomy is vital for neurosurgeons, neurologists, neuro-radiologists and anatomy students, amongst others, to fully comprehend the brain's anatomy with utmost depth. This paper aims to enhance the foundational knowledge of novice physicians in this area. METHOD: A comprehensive literature review was carried out by searching the PubMed and Google Scholar databases using primary keywords related to brain vasculature, without date restrictions...

When The Principles of Humane Experimental Technique was published in 1959, authors William Russell and Rex Burch had a modest goal: to make researchers think about what they were doing in the laboratory - and to do it more humanely. Sixty years later, their groundbreaking book was celebrated for inspiring a revolution in science and launching a new field: The 3Rs of alternatives to animal experimentation. On November 22, 2019, some pioneering and leading scientists and researchers in the field gathered at the Johns Hopkins Bloomberg School of Public Health in Bal-timore for the 60 Years of the 3Rs Symposium: Lessons Learned and the Road Ahead...

BACKGROUND: Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic, and anti-inflammatory activities. OBJECTIVE: This comprehensive review was aimed to critically explore diverse pharmacological activities exhibited by diosmetin. Along with that, this review can also identify potential research areas with an elucidation of the multifactorial underlying signaling mechanism of action of diosmetin in different diseases...

Youth literature allows for the exploration of linguistic and cultural elements, guiding learners to develop their oral interaction skills and critical thinking in the face of sensitive topics such as coexistence, differences, tolerance, xenophobia, and racism. The UNESCO (2010) considers the learning of living together as a fundamental educational mission. Starting from the premise that these values can be embraced by educational systems, this paper examines the effect of storytelling on the development of language and social skills among French as a foreign language learners...

A visiting surgeon described his disappointment with an aspect of the Mayo Clinic in 1914, stating that there was "the almost lack of anything that could be dignified by the term 'lecture.'" One year later, the Mayo Foundation for Medical Education and Research was founded. By 1917, the foundation declared history of medicine a graduate-level subject, and history of medicine questions were included in final oral examinations. In 1920 and 1921, lectures were given on historical topics; however, these lectures petered out, and there were no historical lectures in the official curriculum of 1923 or 1924...

150 years ago, on March 1, 1874, Prof. Dr. Alban Köhler, pioneer in X-ray diagnostics and Co-founder of the German Radiological Society, was born. His memoirs "Röntgenarztes Erdenwallen", an extraordinarily personal, interesting and humorous autobiography of a contemporary witness from the early days of the X-ray era, will be used to commemorate him. This work also focuses on his outstanding X-ray books on skeletal diseases and standard variants.

This article presents a discussion of the evolution of the language of the Science of Unitary Human Beings from the terms used by Martha Rogers in her 1970 book to changes in terms Rogers introduced in her publications over the ensuing years to new terms and language offered by Rogerian scholars before and after Rogers' death in 1994. The article follows from Rogers' insistence that the language of a science, which evolves from general language, should be specific to the level of abstraction of the relevant concepts...

BACKGROUND: Elsholtzia belongs to the Labiatae family, which consists of herbaceous subshrubs and shrubs. Among them, volatile oils are an important chemical component in Elsholtzia, which have various bioactive medicinal and developmental values. METHODS: The references about volatile oils of Elsholtzia in this review were obtained from Web of Science, SciFinder, PubMed, Willy, Elsevier, SpringLink, ACS publications, Google Scholar, Baidu Scholar, Scopus, and CNKI...

OBJECTIVE: We sought to evaluate accurate and reproducible detection of Myxobolus cerebralis (Mc), the causative agent of whirling disease, by using nested polymerase chain reaction (nPCR) and three previously established real-time quantitative PCR (qPCR) assays: K18S (Kelley 18S), C18S (Cavender 18S), and Hsp70 (heat shock protein 70). We used a "fit for purpose" approach combined with intra- and interlaboratory testing to identify a molecular testing method that would be equivalent to the currently accepted nPCR procedure for Mc...

Styrax is a commonly used imported traditional Chinese medicinal material in China. It was introduced to China in the Han Dynasty and was first described as a traditional Chinese medicine in Miscellaneous Records of Famous Physicians(Ming Yi Bie Lu). In this paper, by combing ancient and modern Chinese and foreign herbal medicine books and modern literature, combined with the results of field investigations on the origin of Styrax, the changes of Styrax involving the name, quality evaluation, origin, place of origin, and harvesting and processing were systematically verified...

"Ningbo oriental acupuncture-moxibustion society" was founded in 1930 by ZHANG Junyi . At that era, the enrollment conditions were flexible, the disciplines of warm moxibustion and acupuncture-moxibustion were set and taught by means of face-to-face class and correspondence one. The teaching content included the knowledge of western learning and traditional theory of acupuncture-moxibustion. The Society issued two periodicals, Medical Newspaper of Warm Moxibustion and Oriental Acupuncture and Moxibustion , the staffs of the Society compiled teaching materials such as Warm Moxibustion and Advanced Acupuncture - Moxibustion , translated relevant books and improved the device and herbal medicine of warm moxibustion...

PURPOSE: Healthcare providers are under pressure due to increasing and more complex demands for services. Increased pressure on budgets and human resources adds to an ever-growing problem set. Competent leaders are in demand to ensure effective and well-performing healthcare organisations that deliver balanced results and high-quality services. Researchers have made significant efforts to identify and define determining competencies for healthcare leadership. Broad terms such as competence are, however, inherently at risk of becoming too generic to add analytical value...

BACKGROUND: Increasing noncommunicable diseases in Nigeria are partly related to dietary factors. However, the lack of validated nutrition assessment tools hinders the conduct of nutritional epidemiology research in this population. OBJECTIVES: To develop a Food Frequency Questionnaire (FFQ) and Food Picture Book (FPB) for Nigerian adults, and to assess its reproducibility and validity compared with 24-h dietary recalls (24DRs) during different seasons in the year...

Cartridge cases are commonly collected at crime scenes involving firearms. One of the stages in forensic examination is the determination of the type and model of firearms based on the class characteristics of these cartridge cases. A firearm examiner evaluates the class characteristics on the basis of their knowledge and experience, and by referring to collections of cartridge cases representing class characteristics of different firearms, special databases and reference books. However, this process is highly subjective...

With the advent of large language models, evaluating and benchmarking these systems on important AI problems has taken on newfound importance. Such benchmarking typically involves comparing the predictions of a system against human labels (or a single 'ground-truth'). However, much recent work in psychology has suggested that most tasks involving significant human judgment can have non-trivial degrees of noise. In his book, Kahneman suggests that noise may be a much more significant component of inaccuracy compared to bias, which has been studied more extensively in the AI community...

This article examines the political history of tobacco control policy in South Africa from 1948 to 2018 by drawing on available historical documents, media reports, published books and articles, the grey literature, and face-to-face interviews with key policy actors. Tracing the historical evolution of tobacco control policies in South Africa reveals how embedded opposition from vested interest groups at every stage of the policy process complicates responses to the tobacco issue. This case study demonstrates how, despite such embedded difficulties, a confluence of regime change, evidence-based messaging, political will, policy entrepreneurs, and advocacy coalitions have led to the gradual transformation of tobacco control policy in South Africa over time...