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https://www.readbyqxmd.com/read/28921660/rapid-whole-brain-gray-matter-imaging-using-single-slab-three-dimensional-dual-echo-fast-spin-echo-a-feasibility-study
#1
Hyunyeol Lee, Eung Yeop Kim, Chul-Ho Sohn, Jaeseok Park
PURPOSE: To achieve rapid, high resolution whole-brain gray matter (GM) imaging by developing a novel, single-slab three-dimensional dual-echo fast-spin-echo pulse sequence and GM-selective reconstruction. METHODS: Unlike conventional GM imaging that uses time-consuming double-inversion-recovery preparation, the proposed pulse sequence was designed to have two split portions along the echo train, in which the first half was dedicated to yield short inversion recovery (IR)-induced white matter suppression and variable-flip-angle-induced two-step GM signal evolution while the second half cerebrospinal fluid-only signals...
September 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28921043/slow-wave-activity-and-executive-dysfunction-in-children-with-sleep-disordered-breathing
#2
Jessica A Christiansz, Chloe R Lappin, Aidan J Weichard, Gillian M Nixon, Margot J Davey, Rosemary S C Horne, Sarah N Biggs
PURPOSE: This study aimed to examine slow wave activity (SWA), a marker of homeostatic regulation, as a potential mechanism linking sleep disordered breathing (SDB) with executive dysfunction in children. METHODS: Executive function domains of working memory, spatial planning, information processing, and sustained attention were assessed using the Cambridge Neuropsychological Test Automated Battery (CANTAB) in children (N = 40; 5-12 years) referred for clinical diagnosis of SDB...
September 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28915872/risk-factors-of-chronic-periodontitis-on-healing-response-a-multilevel-modelling-analysis
#3
J Song, H Zhao, C Pan, C Li, J Liu, Y Pan
BACKGROUND: Chronic periodontitis is a multifactorial polygenetic disease with an increasing number of associated factors that have been identified over recent decades. Longitudinal epidemiologic studies have demonstrated that the risk factors were related to the progression of the disease. A traditional multivariate regression model was used to find risk factors associated with chronic periodontitis. However, the approach requirement of standard statistical procedures demands individual independence...
September 15, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28906232/the-pharmaceutical-industry-and-the-canadian-government-folie-%C3%A3-deux
#4
Joel Lexchin
The interest of the pharmaceutical industry is in achieving a profit for its shareholders while the interest of the Canadian government should be in protecting public health. However, over the course of the past few decades the actions of the Canadian government have been tilted in favour of industry in two areas. The first is in the relationship between industry and Health Canada and is manifested in the regulation of clinical trials, the drug approval system, drug safety and promotion. The second is in economic policy as it applies to policies about patent protection, the price of medications and measures taken to incentivize research and development...
August 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/28903566/biobanking-the-first-step-to-successful-liquid-biopsy-experiments
#5
M Almasi, S Sevcikova, M Penka, M Krejci, Z Adam, P Vrublova, T Jelínek, R Hájek
BACKGROUND: Archiving of biological materials in biobanks is considered to be the initial crucial part of research activities. Most often, biobanks are founded for research purposes since they allow collection of sufficient material for analysis of new or testing of previously identified biomarkers. Biobanking needs to quickly react to current needs of researchers as well as clinicians, it is not a rigid system. Laboratory analyses of monoclonal gammopathies are based on separation of plasma cells from bone marrow of patients...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28902237/bonding-efficiency-and-durability-current-possibilities
#6
Adriana Bona Matos, Livia Tosi Trevelin, Beatriz Togoro Ferreira da Silva, Luciana Fávaro Francisconi-Dos-Rios, Luciana Kfouri Siriani, Marcio Vivan Cardoso
Bonding plays a major role in dentistry nowadays. Dental adhesives are used in association with composites to solve many restorative issues. However, the wide variety of bonding agents currently available makes it difficult for clinicians to choose the best alternative in terms of material and technique, especially when different clinical situations are considered. Moreover, although bonding agents allow for a more conservative restorative approach, achieving a durable adhesive interface remains a matter of concern, and this mainly due to degradation of the bonding complex in the challenging oral environment...
August 28, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28901829/resilience-to-discrimination-and-rejection-among-young-sexual-minority-males-and-transgender-females-a-qualitative-study-on-coping-with-minority-stress
#7
Laura Jane Bry, Brian Mustanski, Robert Garofalo, Michelle Nicole Burns
Sexual minority and transgender status is associated with mental health disparities, which have been empirically and theoretically linked to stressors related to social stigma. Despite exposure to these unique stressors, many sexual minority and transgender individuals will not experience mental health disorders in their lifetime. Little is known about the specific processes that sexual minority and transgender youth use to maintain their wellbeing in the presence of discrimination and rejection. Semi-structured interviews were conducted with 10 sexual minority males and transgender females aged 18-22 years, who currently met criteria for an operationalized definition of resilience to depression and anxiety...
September 13, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28900666/-psychotherapeutic-approaches-for-treatment-of-the-elderly
#8
REVIEW
M Hautzinger, P Dykierek, A Fellgiebel, M Hüll
BACKGROUND: This article focusses on the possibilities, varieties, indications, and benefits of psychotherapy with elderly patients. OBJECTIVE: Which basic principles can be differentiated, what theoretical rationales are helpful for psychotherapy with the elderly and what kind and forms of psychotherapy are available? MATERIAL AND METHODS: Based on relevant references and research, clinically relevant and evidence-based psychotherapies are described, to understand the theoretical rationale, the goals, the procedure and main strategies...
September 12, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28898193/molecular-breast-imaging-in-breast-cancer-screening-and-problem-solving
#9
Robin B Shermis, Roberta E Redfern, Jessica Burns, Haris Kudrolli
In the United States, legislative actions in over 28 states require radiologists to notify women who undergo breast screening mammography of their breast density. This has led to increased public interest in supplemental screening, but radiologists have not come to a consensus on a supplemental screening modality. In choosing between the most common options, whole-breast ultrasonography (US) and magnetic resonance (MR) imaging, one must weigh the benefits and drawbacks of each modality, as increased cancer detection may be accompanied by increased examination costs and biopsy rates...
September 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28893238/monitoring-progression-of-clinical-reasoning-skills-during-health-sciences-education-using-the-case-method-a-qualitative-observational-study
#10
Kristina Orban, Maria Ekelin, Gudrun Edgren, Olof Sandgren, Pia Hovbrandt, Eva K Persson
BACKGROUND: Outcome- or competency-based education is well established in medical and health sciences education. Curricula are based on courses where students develop their competences and assessment is also usually course-based. Clinical reasoning is an important competence, and the aim of this study was to monitor and describe students' progression in professional clinical reasoning skills during health sciences education using observations of group discussions following the case method...
September 11, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28891546/work-related-musculoskeletal-pain-among-lebanese-dentists-an-epidemiological-study
#11
S Bou Jaoude, N Naaman, E Nehme, J Gebeily, M Daou
INTRODUCTION: The aim of this study was to evaluate the prevalence of musculoskeletal disorders and identify their associated factors among a group of Lebanese dentists. MATERIALS AND METHODS: A total of 314 Lebanese, dentists completed an anonymous questionnaire that focused on occupational health problems. This study was approved by the ethics committee of Saint-Joseph University of Beirut, Lebanon. The statistical analyses were performed using SPSS for windows...
August 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28891171/innovation-in-health-service-management-adoption-of-project-management-offices-to-support-major-health-care-transformation
#12
Mélanie Lavoie-Tremblay, Monique Aubry, Guylaine Cyr, Marie-Claire Richer, Jean-François Fortin-Verreault, Claude Fortin, Caroline Marchionni
AIM: To explore the characteristics that influence project management offices acceptance and adoption in healthcare sector. BACKGROUND: The creation of project management offices has been suggested as a promising avenue to promote successful organisational change and facilitate evidence-based practice. However, little is known about the characteristics that promote their initial adoption and acceptance in health care sector. This knowledge is important in the context where many organisations are considering implementing project management offices with nurse managers as leaders...
September 10, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28890446/my-time-in-medicine
#13
Joseph J Fins
Through this autobiographical reflection on a life in medicine and bioethics, the author discovers that time is a unifying theme in his work. From his early writing on the regulation of house staff work hours and his abandonment of essentialism and the development of clinical pragmatism as a method of moral problem-solving to his scholarship on end-of-life care and disorders of consciousness, time has been a central heuristic in an effort to bridge ethical theory and clinical practice.
2017: Perspectives in Biology and Medicine
https://www.readbyqxmd.com/read/28885869/improving-student-engagement-in-veterinary-business-studies
#14
Elizabeth Armitage-Chan, Elizabeth Jackson
In a densely packed veterinary curriculum, students may find it particularly challenging to engage in the less overtly clinical subjects, yet pressure from industry and an increasingly competitive employment market necessitate improved veterinary student education in business and management skills. We describe a curriculum intervention (formative reflective assignment) that optimizes workplace learning opportunities and aims to provide better student scaffolding for their in-context business learning. Students were asked to analyze a business practice they experienced during a period of extra-mural studies (external work placement)...
September 8, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28884300/what-every-radiologist-should-know-about-adnexal-torsion
#15
Guillaume Ssi-Yan-Kai, Anne-Laure Rivain, Caroline Trichot, Marie-Chantal Morcelet, Sophie Prevot, Xavier Deffieux, Jocelyne De Laveaucoupet
Adnexal torsion is the fifth most common gynecologic surgical emergency, requiring clinician and radiologist awareness. It involves the rotation of the ovarian tissue on its vascular pedicle leading to stromal edema, hemorrhagic infarction, and necrosis of the adnexal structures with the subsequent sequelae. Expedient diagnosis poses a difficult challenge because the clinical presentation is variable and often misleading. Adnexal torsion can mimic malignancy as it can take a subacute, intermittent, or chronic course, and thereby can be complicated to diagnose...
September 7, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28883202/evaluation-of-an-interactive-visualization-tool-for-the-interpretation-of-pediatric-laboratory-test-results
#16
Johannes Hirschmann, Brita Sedlmayr, Jakob Zierk, Manfred Rauh, Markus Metzler, Hans-Ulrich Prokosch, Dennis Toddenroth
The physiological age-related development of pediatric laboratory results interferes with pathological derangements, which can complicate the interpretation of test results. Recently proposed continuous reference intervals (RIs) promise to be beneficial, although their clinical use may depend on graphical presentations. To estimate the clinical utility of continuous RIs, we developed and evaluated an interactive visualization tool, and examined the differentiation of hemoglobinopathies that is attainable based on the underlying innovative RI model...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28882184/modified-task-based-learning-program-promotes-problem-solving-capacity-among-chinese-medical-postgraduates-a-mixed-quantitative-survey
#17
Yanping Tian, Chengren Li, Jiali Wang, Qiyan Cai, Hanzhi Wang, Xingshu Chen, Yunlai Liu, Feng Mei, Lan Xiao, Rui Jian, Hongli Li
BACKGROUND: Despite great advances, China's postgraduate education faces many problems, for example traditional lecture-based learning (LBL) method provides fewer oppotunities to apply knowledge in a working situation. Task-based learning (TBL) is an efficient strategy for increasing the connections among skills, knowledge and competences. This study aimed to evaluate the effect of a modified TBL model on problem-solving abilities among postgraduate medical students in China. METHODS: We allocated 228 first-year postgraduate students at Third Military Medical University into two groups: the TBL group and LBL group...
September 7, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28882096/delivering-perinatal-depression-care-in-a-rural-obstetric-setting-a-mixed-methods-study-of-feasibility-acceptability-and-effectiveness
#18
Amritha Bhat, Susan Reed, Johnny Mao, Mindy Vredevoogd, Joan Russo, Jennifer Unger, Roger Rowles, Jürgen Unützer
OBJECTIVES: Universal screening for depression during pregnancy and postpartum is recommended, yet mental health treatment and follow-up rates among screen-positive women in rural settings are low. We studied the feasibility, acceptability and effectiveness of perinatal depression treatment integrated into a rural obstetric setting. METHODS: We conducted an open treatment study of a screening and intervention program modified from the Depression Attention for Women Now (DAWN) Collaborative Care model in a rural obstetric clinic...
September 7, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28880163/structured-sparse-principal-components-analysis-with-the-tv-elastic-net-penalty
#19
Amicie de Pierrefeu, Tommy Lofstedt, Fouad Hadj-Selem, Mathieu Dubois, Renaud Jardri, Thomas Fovet, Philippe Ciuciu, Vincent Frouin, Edouard Duchesnay
Principal component analysis (PCA) is an exploratory tool widely used in data analysis to uncover dominant patterns of variability within a population. Despite its ability to represent a data set in a low-dimensional space, PCA's interpretability remains limited. Indeed, the components produced by PCA are often noisy or exhibit no visually meaningful patterns. Furthermore, the fact that the components are usually non-sparse may also impede interpretation, unless arbitrary thresholding is applied. However, in neuroimaging, it is essential to uncover clinically interpretable phenotypic markers that would account for the main variability in the brain images of a population...
September 4, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28879310/education-that-allows-south-korean-colleges-of-dentistry-to-teach-emergency-care
#20
REVIEW
Jeongwan Kang
As the medical environment and dental services change, the importance of educating dentists in responses to systemic emergencies is increasing. The current student-oriented education paradigm is moving towards training students in the abilities required to address the daily crises they will face, while also providing them with the ability to deliver knowledge. Before addressing a patient's situation, emergency physicians begin by diagnosing symptoms. As they must decide on the tests and treatments that are immediately required and must solve problems through interdisciplinary treatment, emergency physicians require additional skills and communication abilities besides clinical knowledge...
December 2016: J Dent Anesth Pain Med
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