Sapna Sharma, Yalamanchili Venkata Subrahmanyam, Harish Ranjani, Sidra Sidra, Dharmeshkumar Parmar, Sangeetha Vadivel, Shanthini Kannan, Harald Grallert, Dandamudi Usharani, Ranjit Mohan Anjana, Muthuswamy Balasubramanyam, Viswanathan Mohan, Adamski Jerzy, Venkateswarlu Panchagnula, Kuppan Gokulakrishnan
BACKGROUND AND AIMS: Obesity has reached epidemic proportions, emphasizing the importance of reliable biomarkers for detecting early metabolic alterations and enabling early preventative interventions. However, our understanding of the molecular mechanisms and specific lipid species associated with childhood obesity remains limited. Therefore, the aim of this study was to investigate plasma lipidomic signatures as potential biomarkers for adolescent obesity. METHODS AND RESULTS: A total of 103 individuals comprising overweight/obese (n = 46) and normal weight (n = 57) were randomly chosen from the baseline ORANGE (Obesity Reduction and Noncommunicable Disease Awareness through Group Education) cohort, having been followed up for a median of 7...
February 23, 2024: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD