keyword
https://read.qxmd.com/read/38506830/the-effect-of-childhood-obesity-on-intraocular-pressure-corneal-biomechanics-retinal-nerve-fiber-layer-and-central-macular-thickness
#21
JOURNAL ARTICLE
Sayime Aydin Eroglu, Ayse Ipek Akyuz Unsal, Furkan Verdi, Imran Kurt Omurlu, Tolga Unuvar, Ahmet Anik
PRCIS: Elevated corneal hysteresis (CH) and resistance factor (CRF) in obese and over-weight children imply weight's effect on corneal biomechanics. Increased Goldmann-correlated intraocular pressure (IOPg) in obese indicates glaucoma risk, emphasizing screening for IOP, retinal changes. PURPOSE: To evaluate the effect of obesity on corneal biomechanics, retinal nerve fibre layer (RNFL) and central macular thicness (CMT) in children. PATIENTS AND METHODS: In this prospective, cross-sectional, comparative study, 146 eyes of normal-weight, over-weight, and obese children aged between 6 to 17 years were evaluated...
March 19, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38505098/alterations-of-dna-methylation-profile-in-peripheral-blood-of-children-with-simple-obesity
#22
JOURNAL ARTICLE
Yi Ren, Peng Huang, Xiaoyan Huang, Lu Zhang, Lingjuan Liu, Wei Xiang, Liqun Liu, Xiaojie He
PURPOSE: To investigate the association between DNA methylation and childhood simple obesity. METHODS: Genome-wide analysis of DNA methylation was conducted on peripheral blood samples from 41 children with simple obesity and 31 normal controls to identify differentially methylated sites (DMS). Subsequently, gene functional analysis of differentially methylated genes (DMGs) was carried out. After screening the characteristic DMGs based on specific conditions, the methylated levels of these DMS were evaluated and verified by pyrosequencing...
December 2024: Health Information Science and Systems
https://read.qxmd.com/read/38504668/developmental-timing-of-child-maltreatment-in-relation-to-obesity-and-substance-use-disorder-in-late-adolescence
#23
JOURNAL ARTICLE
Julia Kobulsky, Krista Schroeder, Brittany Schuler, Emily L Patrick, Yanda Lang, Jingwei Wu
OBJECTIVE: Obesity and substance use are leading preventable causes of mortality, yet their origins in violence remain poorly understood. This study examined child maltreatment in relation to obesity and symptoms consistent with substance use disorder (SUD) in late adolescence, determining the roles of the child maltreatment type and timing, and gender. METHODS: The sample ( N = 1,161) was drawn from the Longitudinal Studies of Child Abuse and Neglect. Obesity and SUD were measured at 18-years...
January 2024: Psychology of Violence
https://read.qxmd.com/read/38504343/lifestyle-intervention-in-children-with-obesity-and-nonalcoholic-fatty-liver-disease-nafld-study-protocol-for-a-randomized-controlled-trial-in-ningbo-city-the-scient-study
#24
JOURNAL ARTICLE
Ping-Ping Zhang, You-Xin Wang, Fang-Jing Shen, Yun-Fei Xing, Jia-Ying Gu, Xue-Ying Li, Han Jin, Shi-Feng Jin, Miao Xu, Hai-Jun Wang, Hui Wang, Li Li
BACKGROUND: The increasing prevalence of childhood obesity has become an urgent public health problem, evidence showed that intervention for childhood obesity bring enormous health benefits. However, an effective individualized intervention strategy remains to be developed, and the accompanying remission of related complications, such as nonalcoholic fatty liver disease (NAFLD), needs to be assessed. This study aimed to develop an m-Health-assisted lifestyle intervention program targeting overweight/obese children and assess its effectiveness on indicators of adiposity and NAFLD...
March 20, 2024: Trials
https://read.qxmd.com/read/38503619/circulatory-levels-of-lysophosphatidylcholine-species-in-obese-adolescents-findings-from-cross-sectional-and-prospective-lipidomics-analyses
#25
JOURNAL ARTICLE
Sapna Sharma, Yalamanchili Venkata Subrahmanyam, Harish Ranjani, Sidra Sidra, Dharmeshkumar Parmar, Sangeetha Vadivel, Shanthini Kannan, Harald Grallert, Dandamudi Usharani, Ranjit Mohan Anjana, Muthuswamy Balasubramanyam, Viswanathan Mohan, Adamski Jerzy, Venkateswarlu Panchagnula, Kuppan Gokulakrishnan
BACKGROUND AND AIMS: Obesity has reached epidemic proportions, emphasizing the importance of reliable biomarkers for detecting early metabolic alterations and enabling early preventative interventions. However, our understanding of the molecular mechanisms and specific lipid species associated with childhood obesity remains limited. Therefore, the aim of this study was to investigate plasma lipidomic signatures as potential biomarkers for adolescent obesity. METHODS AND RESULTS: A total of 103 individuals comprising overweight/obese (n = 46) and normal weight (n = 57) were randomly chosen from the baseline ORANGE (Obesity Reduction and Noncommunicable Disease Awareness through Group Education) cohort, having been followed up for a median of 7...
February 23, 2024: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://read.qxmd.com/read/38500220/childhood-obesity-and-risk-of-alzheimer-s-disease-a-mendelian-randomization-study
#26
JOURNAL ARTICLE
Wenxiang Qing, Yujie Qian
BACKGROUND: Midlife obesity is a modifiable risk factor for Alzheimer's disease. However, the association between childhood obesity and Alzheimer's disease remains largely unknown. Therefore, we conducted a mendelian randomization analysis (MR) to assess the causal link between childhood obesity and Alzheimer's disease. METHODS: Using summary statistics from publicly available genome-wide association studies (GWAS) database, we explored the genetic link between childhood obesity and Alzheimer's disease through a two-sample MR...
March 18, 2024: Archives of Public Health, Archives Belges de Santé Publique
https://read.qxmd.com/read/38500150/gut-microbiota-profiling-in-obese-children-from-southeastern-china
#27
JOURNAL ARTICLE
Jingjing Wang, Peifeng Zhuang, Bin Lin, Haiqing Li, Jinlu Zheng, Wenlin Tang, Wenbin Ye, Xiangjian Chen, Mingping Zheng
Childhood obesity not only has a negative impact on a child's health but is also a significant risk factor for adult obesity and related metabolic disorders, making it a major global public health concern. Recent studies have revealed the crucial role of gut microbiota in the occurrence and development of obesity, in addition to genetic and lifestyle factors. In this study, we recruited 19 normal-weight children and 47 children with varying degrees of obesity. A questionnaire survey was conducted to inquire about the family background, lifestyle habits and dietary composition of the 66 children...
March 18, 2024: BMC Pediatrics
https://read.qxmd.com/read/38499347/distinct-trajectories-of-lung-function-from-childhood-to-mid-adulthood
#28
JOURNAL ARTICLE
Xian Zhang, Andrew R Gray, Robert J Hancox
RATIONALE: Life course trajectories of lung function development and decline influence the risk for lung disease but are poorly documented. OBJECTIVE: To document lung function trajectories from childhood to mid-adult life. METHODS: We modelled forced expiratory volume in 1 s (FEV1 ), forced vital capacity (FVC) and FEV1 /FVC at ages 9, 11, 13, 15, 18, 21, 26, 32, 38 and 45 years from a population-based cohort using latent profile analysis to identify distinct subgroups of participants with similar lung function trajectories...
March 18, 2024: Thorax
https://read.qxmd.com/read/38497991/childhood-overweight-and-obesity-during-and-after-the-covid-19-pandemic
#29
JOURNAL ARTICLE
Anna Fäldt, Sahar Nejat, Natalie Durbeej, Anton Holmgren
No abstract text is available yet for this article.
March 18, 2024: JAMA Pediatrics
https://read.qxmd.com/read/38497070/effect-of-aerobic-exercise-on-anthropometric-parameters-among-indian-primary-school-children
#30
JOURNAL ARTICLE
B Mahalakshmi, Anjana Jagashibhai Chaudhary, Amita Shilpa Gottlieb, N Sivasubramanian, Padmavathi Parthasarathy, G Ramalakshmi, P Jamunarani
Childhood obesity is a global public health concern with significant implications for long-term health. This study addresses the rising rates of obesity among school-age children (10-12 years) and investigates the effectiveness of aerobic exercise interventions in improving anthropometric parameters, specifically focusing on BMI and mid-arm circumference (MAC). The study emphasizes the role of schools in shaping children's behaviors and aims to contribute empirical evidence to inform health promotion strategies for this demographic...
2024: Bioinformation
https://read.qxmd.com/read/38495499/linc00839-in-human-disorders-insights-into-its-regulatory-roles-and-clinical-impact-with-a-special-focus-on-cancer
#31
REVIEW
Yingqiu Hu, Yushan Hu, Xuan Lu, Hongliang Luo, Ziwen Chen
LINC00839 has captured significant attention within a spectrum of human disorders, including acute lung injury, osteoarthritis, and childhood obesity. Notably, aberrant expression patterns of LINC00839 have been observed across diverse cancer tissues and cell lines. LINC00839 emerges as an oncogenic factor in tumorigenesis and exerts a positive influence on tumor-associated behaviors. Its therapeutic potential for various cancers is underscored by its modulatory impact on pivotal signaling pathways, such as PI3K/AKT, OXPHOS, and Wnt/β-catenin...
2024: Journal of Cancer
https://read.qxmd.com/read/38495019/universal-free-school-meals-policy-and-childhood-obesity
#32
JOURNAL ARTICLE
Anna M Localio, Melissa A Knox, Anirban Basu, Tom Lindman, Lina Pinero Walkinshaw, Jessica C Jones-Smith
BACKGROUND AND OBJECTIVES: The Community Eligibility Provision (CEP), a universal free school meals policy, increases school meal participation by allowing schools in low-income areas to provide free breakfast and lunch to all students; however, its impact on obesity remains uncertain. The objective of this study is to estimate the association of CEP with child obesity. METHODS: School obesity prevalence was calculated using BMI measurements collected annually between 2013 and 2019 from students in California public schools in grades 5, 7, and 9...
March 18, 2024: Pediatrics
https://read.qxmd.com/read/38492813/outcome-after-modern-proton-beam-therapy-in-childhood-craniopharyngioma-results-of-the-prospective-registry-study-kiproreg
#33
JOURNAL ARTICLE
M Bischoff, D Ahmad Khalil, S Frisch, C M Bäcker, S Peters, C Friedrich, S Tippelt, R-D Kortmann, B Bison, H L Müller, B Timmermann
BACKGROUND: Craniopharyngiomas (CPs) are rare tumours of the sellar region often leading to significant comorbidities due to their close proximity to critical structures. Aim of this study was to analyse survival outcome and late toxicities after surgery and proton beam therapy (PBT) in childhood CPs. PATIENTS AND METHODS: Within the prospective XXXX study (XXXX), data of 74 childhood patients with CP, receiving PBT between 08/2013-06/2022 were eligible. Late toxicities were analysed according to the grading system of CTCAE 4...
March 14, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38492465/quantitative-or-qualitative-biomolecular-changes-in-blood-serum-composition-induced-by-childhood-obesity-a-fourier-transform-infrared-examination
#34
JOURNAL ARTICLE
Zozan Guleken, Zeynep Ceylan, Serpil Çeçen, Yusuf Elgörmüş, Jozef Cebulski, Joanna Depciuch
Childhood obesity (CO) negatively affects one in three children and stands as the fourth most common risk factor of health and well-being. Clarifying the molecular and structural modifications that transpire during the development of obesity is crucial for understanding its progression and devising effective therapies. The study was indeed conducted as part of an ongoing CO treatment trial, where data were collected from children diagnosed with CO before the initiation of non-drug treatment interventions. Our primary aim was to analyze the biochemical changes associated with childhood obesity, specifically focusing on concentrations of lipids, lipoproteins, insulin, and glucose...
March 13, 2024: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://read.qxmd.com/read/38491133/early-exposure-to-sugar-sweetened-beverages-or-fruit-juice-differentially-influences-adult-adiposity
#35
JOURNAL ARTICLE
David Benton, Hayley A Young
OBJECTIVE: To examine associations between different types of sweet drinks consumed in early life and adult adiposity. DESIGN: The analysis involved the secondary analysis of the Avon Longitudinal Study of Parents and Children which followed children from birth to 24 years. Adiposity was measured using Dual-energy X-ray absorptiometry while food frequency questionnaires and diaries monitored diet. 'Early exposure' to sweet drinks was defined as giving a sugar-sweetened beverage or 100% fruit juice (FJ), before two years of age...
March 15, 2024: European Journal of Clinical Nutrition
https://read.qxmd.com/read/38490693/global-relevance-of-mgrs-growth-standards-the-case-of-india
#36
REVIEW
Vandana Prasad, Dipa Sinha, Rohit James Joseph
The most common measures of childhood undernutrition are based on anthropometric measures such as height-for-age (stunting/chronic undernutrition) and weight-for-height (wasting/acute undernutrition). It is well recognised that the determinants of undernutrition are multiple, including food intake, dietary diversity, health, sanitation and women's status. Currently, most countries across the world including India use the globally accepted WHO-Multicentre Growth Reference Study (MGRS) growth standards (2006) for the purposes of measurement as well as for evaluating progress on these metrics...
March 15, 2024: BMJ Paediatrics Open
https://read.qxmd.com/read/38489826/preventing-childhood-obesity-in-general-practice-a-qualitative-study-of-gps-practice-nurses-and-practice-managers
#37
JOURNAL ARTICLE
Michelle Gooey, Haimanot Hailu, Elizabeth Sturgiss, Jenny Advocat, Heidi Bergmeier, Helen Skouteris
BACKGROUND: General practitioners (GPs) in Australia have an important role to play in preventing childhood obesity. Activities such as growth monitoring and promotion of healthy behaviours can contribute to obesity prevention efforts; however, the practicalities of how this is done are poorly documented. OBJECTIVES: Objectives were to understand current attitudes and practices regarding promoting healthy childhood growth and development and preventing childhood obesity in general practice, and identify practical barriers and enablers to routinely incorporating this into general practice based on the observations and personal experiences of general practice staff...
March 15, 2024: Family Practice
https://read.qxmd.com/read/38488037/reversibility-of-hyperglycemic-states-in-children-with-obesity-diagnostic-pitfalls-in-the-assessment-of-glucose-metabolism-in-children-and-adolescents-with-obesity
#38
JOURNAL ARTICLE
Anna Iwańska, Małgorzata Wójcik, Ewa Szczudlik, Anna Stępniewska, Jerzy B Starzyk
OBJECTIVE: Disorders of glucose metabolism in children with obesity are less common than in adults. There is also evidence that they may be transient. The aim of this study was to determine the prevalence of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), type 2 diabetes mellitus (DM2) and its reversibility in pediatric patients with obesity and to define the factors determining the reversibility of prediabetes or progression to diabetes. METHODS: Retrospective analysis included 573 patients with obesity (mean BMI Z-score 4...
March 15, 2024: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/38487472/retraction-barriers-and-facilitators-of-childhood-obesity-prevention-policies-a-systematic-review-and-meta-synthesis
#39
(no author information available yet)
[This retracts the article DOI: 10.3389/fped.2022.1054133.].
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38484606/obesity-in-latinx-and-white-u-s-military-veterans-mental-health-psychosocial-burden-non-suicidal-self-injury-and-suicidal-behavior
#40
JOURNAL ARTICLE
Elina A Stefanovics, Carlos M Grilo, Marc N Potenza, Robert H Pietrzak
Obesity disproportionately affects Latinx communities and is linked to an increased risk of mental health problems. Military veterans are more likely to develop mental health problems, but the role of Latinx ethnicity in moderating the association between obesity and these problems is unclear. To address this gap, this study examined psychiatric and psychosocial correlates of obesity in a nationally representative sample of Latinx and White U.S. military veterans. Data were analyzed from the 2019-2020 National Health and Resilience in Veterans Study, which surveyed 3524 Latinx and White veterans...
March 8, 2024: Psychiatry Research
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