Tommer Nir, Reut Raizman, Inbar Meningher, Yael Jacob, Kuang-Han Huang, Arthur E Schwartz, Jess W Brallier, Helen Ahn, Prantik Kundu, Cheuk Y Tang, Bradley N Delman, Patrick J McCormick, Julia Scarpa, Mary Sano, Stacie G Deiner, Abigail Livny, Mark G Baxter, Joshua S Mincer
BACKGROUND: Arousal and awareness are two important components of consciousness states. Functional neuroimaging has furthered our understanding of cortical and thalamocortical mechanisms of awareness. Investigating the relationship between subcortical functional connectivity and arousal has been challenging owing to the relatively small size of brainstem structures and thalamic nuclei, and their depth in the brain. METHODS: Resting state functional MRI scans of 72 healthy volunteers were acquired before, during, 1 h after, and 1 day after sevoflurane general anaesthesia...
January 2022: British Journal of Anaesthesia