Mia Stanković, Jakob Kljun, Nevena Lj Stevanović, Jelena Lazic, Sanja Skaro Bogojevic, Sandra Vojnovic, Matija Zlatar, Jasmina Nikodinovic-Runic, Iztok Turel, Miloš I Djuran, Biljana Đ Glišić
Inspired by the emergence of resistance to currently available antifungal therapy and by the great potential of metal complexes for the treatment of various diseases, we synthesized three new silver(I) complexes containing clinically used antifungal azoles as ligands, [Ag(ecz)2 ]SbF6 (1, ecz is econazole), {[Ag(vcz)2 ]SbF6 } n (2, vcz is voriconazole), and [Ag(ctz)2 ]SbF6 (3, ctz is clotrimazole), and investigated their antimicrobial properties. The synthesized complexes were characterized by mass spectrometry, IR, UV-vis and 1 H NMR spectroscopy, cyclic voltammetry, and single-crystal X-ray diffraction analysis...
January 9, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry