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https://www.readbyqxmd.com/read/29147070/evidences-of-a-new-psychobiotic-formulation-on-body-composition-and-anxiety
#1
Carmela Colica, Ennio Avolio, Patrizio Bollero, Renata Costa de Miranda, Simona Ferraro, Paola Sinibaldi Salimei, Antonino De Lorenzo, Laura Di Renzo
Background: Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods: Eligible patients were randomly divided into three groups: psychobiotics oral suspension group (POSG); dietary treatment group (DTG); combined treatment group (CTG)...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29145858/cognitive-appraisal-of-exposure-to-specific-types-of-trauma-a-study-of-gender-differences
#2
Dana-Cristina Herta, Bogdan Nemes, Doina Cozman
BACKGROUND: The role of gender in posttraumatic cognitions has increasingly been approached. The current study comparatively evaluates posttraumatic cognitions in men and women exposed to specific nonsexual trauma (motor vehicle accidents, work - related accidents, burns). METHODS: Posttraumatic cognitions and posttraumatic stress symptoms were comparatively assessed in 53 men and 37 women treated in 3 Romanian primary care units after specific accidental trauma...
November 16, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29131389/a-new-porcine-vascularized-tibial-bone-allotransplantation-model-anatomy-and-surgical-technique
#3
Dimitra Kotsougiani, Joost I Willems, Alexander Y Shin, Patricia F Friedrich, Caroline A Hundepool, Allen T Bishop
INTRODUCTION: Vascularized bone allotransplantation may provide new options for reconstruction of segmental defects if problems of long-term immune modulation can be solved. The current literature lacks an orthotopic large animal model, limited to bone and without the confounding effects of other tissue types, permitting a multifaceted evaluation before new methods are used clinically. The purpose of this study was to develop a large animal model for vascularized bone allotransplantation...
November 13, 2017: Microsurgery
https://www.readbyqxmd.com/read/29130224/-interpretation-of-2017-national-comprehensive-cancer-network-nccn-guidelines-for-the-diagnosis-and-treatment-of-esophageal-squamous-cell-carcinoma-through-the-new-tnm-staging-of-esophageal-carcinoma-eighth-edition-by-the-union-for-international-cancer-control
#4
Wentao Fang
The eighth edition of Union for International Cancer Control (UICC) and the American Joint Committee on Cancer(AJCC) announced in 2017 the new staging of esophageal cancer, focusing on the prognostic significance of accurate staging and lymph node metastasis before treatment of esophageal carcinoma, the rationality of early tumor therapy, and the importance of induction therapy. The modified 2017 edition of the National Comprehensive Cancer Network (NCCN) guidelines, based on above contents matching UICC/AJCC eighth edition of the new staging of esophageal cancer, added preoperative clinical staging to guide the selection of treatment, and re-defined the indications of endoscopic resection and operation for early esophageal squamous cell carcinoma, meanwhile emphasized once again the importance of preoperative induction therapy for locally advanced esophageal squamous cell carcinoma...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29130220/-current-research-progress-and-thinking-of-fecal-microbiota-transplantation-for-the-treatment-of-gastrointestinal-disorders
#5
Ning Li, Hongliang Tian
Fecal microbiota transplantation (FMT), also known as fecal bacteriotherapy or fecal infusion, consists of injection of a liquid filtrate of feces from a healthy donor into the gastrointestinal tract of a recipient individual. FMT has been proposed as a therapeutic approach for functional diseases of the gastrointestinal tract by reestablishment of a wide diversity of intestinal flora. Clostridium difficile infection (CDI) treatment guideline from American Gastroenterology Association (AGA) recommends that FMT can be used as the treatment protocols of relapse CDI...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29130137/assessment-of-the-equivalent-dipole-layer-source-model-in-the-reconstruction-of-cardiac-activation-times-on-the-basis-of-bspms-produced-by-an-anisotropic-model-of-the-heart
#6
Arno M Janssen, Danila Potyagaylo, Olaf Dössel, Thom F Oostendorp
Promising results have been reported in noninvasive estimation of cardiac activation times (AT) using the equivalent dipole layer (EDL) source model in combination with the boundary element method (BEM). However, the assumption of equal anisotropy ratios in the heart that underlies the EDL model does not reflect reality. In the present study, we quantify the errors of the nonlinear AT imaging based on the EDL approximation. Nine different excitation patterns (sinus rhythm and eight ectopic beats) were simulated with the monodomain model...
November 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29128759/a-conduction-velocity-adapted-eikonal-model-for-electrophysiology-problems-with-re-excitability-evaluation
#7
Cesare Corrado, Nejib Zemzemi
Computational models of heart electrophysiology achieved a considerable interest in the medical community as they represent a novel framework for the study of the mechanisms underpinning heart pathologies. The high demand of computational resources and the long computational time required to evaluate the model solution hamper the use of detailed computational models in clinical applications. In this paper, we present a multi-front eikonal algorithm that adapts the conduction velocity (CV) to the activation frequency of the tissue substrate...
November 3, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29127597/development-of-a-practical-outcome-measure-to-account-for-individual-differences-in-quality-of-life-appraisal-the-brief-appraisal-inventory
#8
Bruce D Rapkin, Iliana Garcia, Wesley Michael, Jie Zhang, Carolyn E Schwartz
BACKGROUND: The present study evaluated the distributional and structural characteristics and explanatory power of the 23-item Brief Appraisal Inventory (BAI), a more practical appraisal measure for use in clinical research and practice. METHODS: A heterogeneous, online cohort of chronic disease patients and caregivers completed the BAI, along with demographics, comorbidities, PROMIS-10, and the Brief NEO Personality Inventory. Principal components, bivariate, and linear and logistic regression analyses addressed BAI item distributions, structure, and construct validity...
November 10, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29124483/stochastic-integer-programming-for-multi-disciplinary-outpatient-clinic-planning
#9
A G Leeftink, I M H Vliegen, E W Hans
Scheduling appointments in a multi-disciplinary clinic is complex, since coordination between disciplines is required. The design of a blueprint schedule for a multi-disciplinary clinic with open access requirements requires an integrated optimization approach, in which all appointment schedules are jointly optimized. As this currently is an open question in the literature, our research is the first to address this problem. This research is motivated by a Dutch hospital, which uses a multi-disciplinary cancer clinic to communicate the diagnosis and to explain the treatment plan to their patients...
November 9, 2017: Health Care Management Science
https://www.readbyqxmd.com/read/29121207/interfering-with-inner-speech-selectively-disrupts-problem-solving-and-is-linked-with-real-world-executive-functioning
#10
Gregory L Wallace, Cynthia S Peng, David Williams
Purpose: According to Vygotskian theory, verbal thinking serves to guide our behavior and underpins critical self-regulatory functions. Indeed, numerous studies now link inner speech usage with performance on tests of executive function (EF). However, the selectivity of inner speech contributions to multifactorial executive planning performance and links with real-world functioning are limited. Therefore, the present study seeks to fill this gap in our knowledge. Method: Fifty-one adults completed the Tower of London under 2 conditions, (a) articulatory suppression and (b) foot tapping, and provided self-ratings of real-world executive functioning (utilizing the Behavior Rating Inventory of Executive Function-Adult Version; Roth, Isquith, & Gioia, 2006)...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29120912/effects-of-a-system-thinking-based-simulation-program-for-congestive-heart-failure
#11
Hyeon-Young Kim, Eun Kyoung Yun
This study evaluated a system thinking-based simulation program for the care of patients with congestive heart failure. Participants were 67 undergraduate nursing students from a nursing college in Seoul, South Korea. The experimental group was given a 4-hour system-thinking program and a 2-hour simulation program, whereas the control group had a 4-hour case study and a 2-hour simulation program. There were significant improvements in critical thinking in both groups, but no significant group differences between educational methods (F = 3...
November 8, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/29120320/adapting-maternal-health-practice-to-co-morbidities-and-social-inequality-a-systematic-approach
#12
Aditi Iyer, V Srinidhi, Anuradha Sreevathsa, Gita Sen
The process of adapting universal guidelines to local institutional and cultural settings is recognized as important to their implementation and uptake. However, clarity on what, why and how to adapt in an evidence-based manner is still somewhat elusive. Health providers in low and middle income country contexts often have to deal with widely present co-morbidities and social inequalities among pregnant women. Since neither of these problems finds adequate discussion within the usual guidelines, and given the continual pressures posed by resource scarcity, health providers respond through ad hoc adaptations inimical to maternal safety and equity...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29117913/two-interventions-for-patients-with-major-depression-and-severe-chronic-obstructive-pulmonary-disease-impact-on-dyspnea-related-disability
#13
George S Alexopoulos, Jo Anne Sirey, Samprit Banerjee, Danielle S Jackson, Dimitris N Kiosses, Cristina Pollari, Richard S Novitch, Amanda Artis, Patrick J Raue
OBJECTIVE: The Personalized Intervention for Depressed Patients with Chronic Obstructive Pulmonary Disease (PID-C) is an intervention aiming to help patients adhere to their rehabilitation and care. This study tested the hypothesis that the Problem-Solving Adherence (PSA) intervention, which integrates problem-solving into adherence enhancement procedures, reduces dyspnea-related disability more than PID-C. Exploratory analyses sought to identify patients with distinct dyspnea-related disability trajectories and to compare their clinical profiles...
October 10, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29104688/one-step-surgery-for-cutaneous-melanoma-we-cannot-solve-our-problems-with-the-same-thinking-we-used-when-we-created-them
#14
Georgi Tchernev
One step melanoma surgery is, in fact, an innovative combined method for diagnosis and treatment of cutaneous melanoma (at the same time). The methodology allows an accurate assessment of the actual status of the affected patients by 1) clinical status, dermatoscopy, high-frequent ultrasonography (HFUS) of the pigmented lesion (eventually in combination with normal lymph nodes ultrasonography), followed by a single surgical intervention. Within this intervention, the primary tumour is removed with the appropriate surgical field, with or without parallel detection and draining lymph node biopsy (depending on the established tumour thickness)...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29104559/optimizing-the-definitions-of-stroke-transient-ischemic-attack-and-infarction-for-research-and-application-in-clinical-practice
#15
Anne L Abbott, Mauro Silvestrini, Raffi Topakian, Jonathan Golledge, Alejandro M Brunser, Gert J de Borst, Robert E Harbaugh, Fergus N Doubal, Tatjana Rundek, Ankur Thapar, Alun H Davies, Anthony Kam, Joanna M Wardlaw
Background and purpose: Until now, stroke and transient ischemic attack (TIA) have been clinically based terms which describe the presence and duration of characteristic neurological deficits attributable to intrinsic disorders of particular arteries supplying the brain, retina, or (sometimes) the spinal cord. Further, infarction has been pathologically defined as death of neural tissue due to reduced blood supply. Recently, it has been proposed we shift to definitions of stroke and TIA determined by neuroimaging results alone and that neuroimaging findings be equated with infarction...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29101641/an-x-ray-free-method-to-accurately-identify-the-elbow-flexion-extension-axis-for-the-placement-of-a-hinged-external-fixator
#16
Jian Song, Hui Ding, Wei Han, Junqiang Wang, Guangzhi Wang
PURPOSE: Identifying the elbow flexion-extension (F-E) movement axis is important for placing a hinged elbow external fixator. An X-ray fluoroscopy-based method is widely used in clinical practice, exposing the patient and surgeons to high doses of radiation. Additionally, the accuracy and repeatability of the fluoroscopy-based method are very low and affected by subjective factors. METHODS: To solve this problem, an X-ray-free method based on kinematics analysis was proposed to identify the elbow F-E movement axis, and a navigation system was built to guide the placement of the elbow external fixator...
November 3, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29101575/current-and-future-treatments-for-lysosomal-storage-disorders
#17
REVIEW
David P W Rastall, Andrea Amalfitano
Purpose of review Lysosomal storage disorders (LSDs) are a class of genetic disorders that are a testing ground for the invention of novel therapeutics including enzyme replacement therapy (ERT), substrate reduction therapy (SRT), gene therapy, and hematopoietic stem cell transplant (HSCT). This review summarizes recently approved drugs, then examines the successful clinical trials in gene therapy and HSCT. Recent findings The FDA has recently approved a second SRT by reversing an earlier FDA decision, suggesting a favorable regulatory landscape going forward...
November 4, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29100838/alice-a-tool-for-automatic-localization-of-intra-cranial-electrodes-for-clinical-and-high-density-grids
#18
Mariana P Branco, Anna Gaglianese, Daniel Glen, Dora Hermes, Ziad S Saad, Natalia Petridou, Nick F Ramsey
BACKGROUND: Electrocorticographic (ECoG) measurements require the accurate localization of implanted electrodes with respect to the subject's neuroanatomy. Electrode localization is particularly relevant to associate structure with function. Several procedures have attempted to solve this problem, namely by co-registering a post-operative computed tomography (CT) scan, with a pre-operative magnetic resonance imaging (MRI) anatomy scan. However, this type of procedure requires a manual and time-consuming detection and transcription of the electrode coordinates from the CT volume scan and restricts the extraction of smaller high-resolution ECoG grid electrodes due to the downsampling of the CT...
October 31, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29100352/genetic-variations-in-terc-and-tert-genes-are-associated-with-renal-cell-carcinoma-risk-in-a-chinese-han-population
#19
Dapeng Wu, Guodong Zhu, Jin Zeng, Wenbin Song, Ke Wang, Xinyang Wang, Peng Guo, Dalin He
Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system, the pathogenesis of RCC is still unclear. It is reported that genetic variations in telomere length related-genes TERT and TERC are involved in the many types of cancers. However, little is known about the association between TERT and TERC polymorphisms and susceptibility to RCC risk. To solve this problem, a total of 293 patients with primary renal cell carcinoma and 459 healthy people were recruited in our study. Six SNPs of TERC and TERT were genotyped, and association analysis was performed...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29100202/the-support-control-continuum-an-investigation-of-staff-perspectives-on-factors-influencing-the-success-or-failure-of-de-escalation-techniques-for-the-management-of-violence-and-aggression-in-mental-health-settings
#20
Owen Price, John Baker, Penny Bee, Karina Lovell
BACKGROUND: De-escalation techniques are recommended to manage violence and aggression in mental health settings yet restrictive practices continue to be frequently used. Barriers and enablers to the implementation and effectiveness of de-escalation techniques in practice are not well understood. OBJECTIVES: To obtain staff descriptions of de-escalation techniques currently used in mental health settings and explore factors perceived to influence their implementation and effectiveness...
October 6, 2017: International Journal of Nursing Studies
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