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https://www.readbyqxmd.com/read/29341797/visual-dependence-affects-postural-sway-responses-to-continuous-visual-field-motion-in-individuals-with-cerebral-palsy
#1
Yawen Yu, Richard T Lauer, Carole A Tucker, Elizabeth D Thompson, Emily A Keshner
The current study aimed to explore the impact of visual dependence on sensorimotor coupling of postural sway and visual motion in adults and teens with spastic cerebral palsy (CP). We hypothesized that individuals with CP would exhibit greater magnitudes of sway than healthy individuals, and the presence of visual dependence (VD) would produce instability in the direction of visual motion. Participants stood in a virtual environment in which the visual scene remained static or continuously rotated 30 degree/second in pitch-up or pitch-down...
January 17, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29341424/fetal-ultrasonographic-findings-including-cerebral-hyperechogenicity-in-a-patient-with-non-lethal-form-of-raine-syndrome
#2
Kei Tamai, Katsuhiko Tada, Akihito Takeuchi, Makoto Nakamura, Hidenori Marunaka, Yosuke Washio, Hiroyuki Tanaka, Fuyuki Miya, Nobuhiko Okamoto, Misao Kageyama
Raine syndrome is a rare osteosclerotic bone dysplasia characterized by craniofacial anomalies and intracranial calcification. Most patients with Raine syndrome are of Arab ancestry and die during the neonatal period. We herein report a Japanese patient with non-lethal Raine syndrome who presented with characteristic cerebral hyperechogenicity and a hypoplastic nose by fetal ultrasonography. She was admitted to the NICU due to pyriform aperture stenosis. Craniofacial abnormalities, intracranial calcification, osteosclerosis, chondrodysplasia punctata, and a mutation of FAM20C was identified...
January 17, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29340950/dermatologic-lesions-submitted-to-an-oral-and-maxillofacial-pathology-biopsy-service-an-analysis-of-2487-cases
#3
Rekha Reddy, Liya Davidova, Indraneel Bhattacharyya, Donald M Cohen, Mohammed N Islam, Sarah G Fitzpatrick
Skin lesions are often submitted to oral and maxillofacial pathology practices. The purpose of this study is to evaluate the frequency, distribution, variability, and composition of dermatologic lesions within a large oral and maxillofacial pathology biopsy service. An IRB-approved retrospective search of skin lesions diagnosed at University of Florida oral and maxillofacial pathology biopsy service between 1994 and 2015 was performed. 2487 cases were included in the study. Gender was reported in 2466 cases, of which 59% were male and 41% female...
January 16, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29340693/can-granulomatosis-with-polyangiitis-be-diagnosed-earlier-in-primary-care-a-case-control-study
#4
F A Pearce, R B Hubbard, M J Grainge, R A Watts, A Abhishek, P C Lanyon
Background: People with granulomatosis with polyangiitis (GPA) commonly described long delays before diagnosis. Aim: To study the natural history of GPA prior to diagnosis using primary care data, and determine whether clinical features could be identified to help earlier diagnosis. Design: Case-control study using the Clinical Practice Research Datalink. Methods: We compared primary care activity and clinical features between cases and 10 matched controls...
January 1, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29340598/the-risk-of-skin-necrosis-following-hyaluronic-acid-filler-injection-in-patients-with-a-history-of-cosmetic-rhinoplasty
#5
Reza M Robati, Fatemeh Moeineddin, Mina Almasi-Nasrabadi
Background: As the number of patients using dermal filler for face augmentation increases, the number of adverse events associated with injection may increase. Unpredictable repositioning of blood vessels and a more tenuous blood supply in the operated nose may increase the risk of ischemia, necrosis and vascular embolism following the filler injection. Objectives: To highlight the importance of the patient's history of previous cosmetic procedures including rhinoplasty in the emergence of vascular complications...
January 11, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29338427/lipid-nanoparticles-for-intranasal-administration-application-to-nose-to-brain-delivery
#6
Luigi Battaglia, Pier Paolo Panciani, Elisabetta Muntoni, Maria Teresa Capucchio, Elena Biasibetti, Pasquale De Bonis, Silvia Mioletti, Marco Fontanella, Shankar Swaminathan
The blood brain barrier is a functional barrier allowing the entry into the brain of only essential nutrients, excluding other molecules. Its structure, although essential to keep the harmful entities out, is also a major roadblock for pharmacological treatment of brain diseases. Several alternative invasive drug delivery approaches, such as transcranial drug delivery and disruption of blood brain barrier have been explored, with limited success and several challenges. Intranasal delivery is a non-invasive methodology, which bypasses the systemic circulation, and, through the intra- and extra- neuronal pathways, provides direct brain drug delivery...
January 17, 2018: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/29337433/numerical-simulation-of-two-consecutive-nasal-respiratory-cycles-toward-a-better-understanding-of-nasal-physiology
#7
Ludovic de Gabory, Nicolas Reville, Yannick Baux, Nicolas Boisson, Laurence Bordenave
BACKGROUND: Computational fluid dynamic (CFD) simulations have greatly improved the understanding of nasal physiology. We postulate that simulating the entire and repeated respiratory nasal cycles, within the whole sinonasal cavities, is mandatory to gather more accurate observations and better understand airflow patterns. METHODS: A 3-dimensional (3D) sinonasal model was constructed from a healthy adult computed tomography (CT) scan which discretized in 6.6 million cells (mean volume, 0...
January 16, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29336898/effect-of-transcranial-direct-current-stimulation-on-short-term-and-long-term-treatment-of-chronic-tinnitus
#8
Hamidreza Abtahi, Ahmadreza Okhovvat, Somaiie Heidari, Azar Gharagazarloo, Motahare Mirdamadi, Mohammad Hossein Nilforoush, Hossein Ghazavi
OBJECTIVE: This study was conducted to investigate the effectiveness of anodal and cathodal methods in reducing the intensity of tinnitus and to compare them with the control. METHODOLOGY: This randomized double-blind clinical trial with case and control groups was conducted in Al-Zahra Hospital in Isfahan between 2015 and 2016. In this trial, 51 patients with tinnitus, for at least one year, were selected among those outpatients visiting the throat, nose and ear clinic within this period...
January 6, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29335112/december-consultation-3
#9
Ricardo Menon Nosé
No abstract text is available yet for this article.
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29333816/national-health-care-network-for-children-with-oral-clefts-organization-functioning-and-preliminary-outcomes
#10
Agustina Cassinelli, Nadia Pauselli, Agustina Piola, Claudia Martinelli, José L Alves de Azeved, María P Bidondo, Boris Groisman, Pablo Barbero, Rosa Liascovich, Ana Sala
INTRODUCTION: Oral clefts are major congenital anomalies that may affect the lip and/or palate, and that may also involve the nose and nostrils. In Argentina, their prevalence is approximately 15 per 10 000 births. In 2015, the Ministry of Health of Argentina created a national health care network for children with oral clefts in Argentina through the joint work with the National Registry of Congenital Anomalies (Red Nacional de Anomalías Congénitas, RENAC) (coordinating center for the national network) and the SUMAR Program...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333582/outpatient-erbium-yag-2940%C3%A2-nm-laser-treatment-for-snoring-a-prospective-study-on-40-patients
#11
Isabelle Fini Storchi, Steven Parker, Francesca Bovis, Stefano Benedicenti, Andrea Amaroli
Snoring is a sleep phenomenon due to the partial upper airway obstruction during sleep which causes vibration of the tissues of the rhino-oro-hypopharynx and less frequently the larynx. This study evaluated the use and effectiveness of the erbium:YAG 2940-nm laser as an adjunctive in providing treatment for patients suffering from chronic snoring-related sleep disorders. A prospective study of 40 consecutive patients with snoring and sleep disorders was performed, assessing data before and after three Er:YAG laser treatment sessions...
January 15, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29333423/long-term-outcomes-after-natural-orifice-specimen-extraction-versus-conventional-laparoscopy-assisted-surgery-for-rectal-cancer-a-matched-case-control-study
#12
Jun Seok Park, Hyun Kang, Soo Yeun Park, Hye Jin Kim, In Taek Lee, Gyu-Seog Choi
Purpose: The aim of this study was to compare the long-term outcomes of total laparoscopic surgery with Natural Orifice Specimen Extraction (NOSE) with those for conventional laparoscopy (CL)-assisted surgery for treating rectal cancers. Methods: We reviewed the prospectively collected records of 844 patients (163 NOSE and 681 CL) who underwent curative surgery for mid- or upper rectal cancers from January 2006 to November 2012. We applied propensity score analyses and compared oncological outcomes for the NOSE and CL groups in a 1:1 matched cohort...
January 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29331405/reliability-and-validity-of-the-turkish-version-of-the-consensus-auditory-perceptual-evaluation-of-voice-cape-v
#13
Esra Özcebe, Fatma Esen Aydinli, Tuğçe Karahan Tiğrak, Önal İncebay, Taner Yilmaz
OBJECTIVES: The main purpose of this study was to culturally adapt the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) to Turkish and to evaluate its internal consistency, validity, and reliability. MATERIALS AND METHODS: The Turkish version of CAPE-V was developed, and with the use of a prospective case-control design, the voice recordings of 130 participants were collected according to CAPE-V protocol. Auditory-perceptual evaluation was conducted according to CAPE-V and Grade, Roughness, Breathiness, Asthenia, and Strain (GRBAS) scale by two ear, nose, and throat specialists and two speech and language therapists...
January 11, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29331281/-do-online-ratings-reflect-structural-differences-in-healthcare-the-example-of-german-physician-rating-websites
#14
Nina Meszmer, Lena Jaegers, Oliver Schöffski, Martin Emmert
BACKGROUND: Previous surveys have shown that patient satisfaction varies with the regional supply of physicians. Online ratings on physician-rating websites represent a relatively new instrument to display patient satisfaction results. The aim of this study was (1) to assess the current state of online ratings for two medical disciplines (dermatologists and ear, nose and throat (ENT) specialists), and (2) to analyze online derived patient satisfaction results according to the physician density in Germany...
January 10, 2018: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29331137/molecular-dynamics-based-enhanced-sampling-of-collective-variables-with-very-large-time-steps
#15
Pei-Yang Chen, Mark E Tuckerman
Enhanced sampling techniques that target a set of collective variables and that use molecular dynamics as the driving engine have seen widespread application in the computational molecular sciences as a means to explore the free-energy landscapes of complex systems. The use of molecular dynamics as the fundamental driver of the sampling requires the introduction of a time step whose magnitude is limited by the fastest motions in a system. While standard multiple time-stepping methods allow larger time steps to be employed for the slower and computationally more expensive forces, the maximum achievable increase in time step is limited by resonance phenomena, which inextricably couple fast and slow motions...
January 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29331009/cyanoacrylate-injury-to-the-ear-canal
#16
Assad Khan, Sinthuja Neminathan, Anita Sonsale, Atilla Dezso
This is a case regarding a 35-year-old gentleman who presented to the Accident and Emergency department at Walsall Manor Hospital. He had mistakenly placed cyanoacrylate ('superglue') into his right ear canal in the early morning. In terms of its removal, an initial attempt was made in the Ear, Nose and throat (ENT) outpatient clinic which proved to be unsuccessful due to the amount of discomfort it caused the patient. Therefore, it had to be removed under general anaesthesia.
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330190/influence-of-pig-farming-on-the-human-s-nasal-microbiota-the-key-role-of-the-airborne-microbial-communities
#17
Julia G Kraemer, Alban Ramette, Suzanne Aebi, Anne Oppliger, Markus Hilty
It has been hypothesized that the environment can influence the composition of the nasal microbiota. However, the direct influence of pig farming on the anterior and posterior nasal microbiota is unknown. Using a cross-sectional design, pig farms (n=28) were visited in 2014-2015 and nasal swabs from 43 pig farmers and 56 pigs as well as 27 air samples taken in the vicinity of pig enclosure were collected. As controls, nasal swabs from 17 cow farmers and 26 non-animal exposed individuals were also included. Analyses of the microbiota were performed based on 16S rRNA amplicon sequencing and the DADA2 pipeline to define sequence variants (SVs)...
January 12, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29330120/an-update-on-the-role-of-nanovehicles-in-nose-to-brain-drug-delivery
#18
REVIEW
Yunhai Feng, Haisheng He, Fengqian Li, Yi Lu, Jianping Qi, Wei Wu
A quantitative analysis has cast doubt over the limited advantages provided by particles for nose-to-brain (NTB) drug delivery. Thus, it is imperative to identify the role of nanovehicles in NTB drug delivery. If nanocarriers are used merely as an option to improve various properties of the drugs or the formulations, it is difficult for them to outperform conventional formulations, such as solutions or gels. However, nanovehicles bring about special features, such as maintenance of the solubilized state of drugs, sustained or delayed release, and enhanced penetration because of surface modifications, all of which lead to enhanced NTB delivery efficiency...
January 9, 2018: Drug Discovery Today
https://www.readbyqxmd.com/read/29330003/effects-of-5-ht5a-receptor-blockade-on-amnesia-or-forgetting
#19
L Aparicio-Nava, L A Márquez-García, A Meneses
Previously the effects (0.01-3.0 mg/kg) of post-training SB-699551 (a 5-HT5A receptor antagonist) were reported in the associative learning task of autoshaping, showing that SB-699551 (0.1 mg/kg) decreased lever-press conditioned responses (CR) during short-term (STM; 1.5-h) or (3.0 mg/kg) long-term memory (LTM; 24-h); relative to the vehicle animals. Moreover, as pro-cognitive efficacy of SB-699551 was reported in the ketamine-model of schizophrenia. Hence, firstly aiming improving performance (conditioned response, CR), in this work autoshaping lever-press vs...
January 9, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29328804/replacement-of-the-nose
#20
Harold Ellis
Today's reconstructive surgeons may not be aware that replacement of the nose was carried out successfully as long ago as the 16th century by the surgeon Gaspar Taliacozzo of Bologna, Italy, who published a detailed and illustrated account of his operation in 1597. This procedure comprised raising a flap of skin from the upper arm to reconstruct the nose. The arm was kept in place, with the hand resting on the patient's head, using elaborate splinting until adherence had taken place; the flap was then detached from the donor arm...
May 2017: Journal of Perioperative Practice
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