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https://www.readbyqxmd.com/read/29166423/exhaled-and-nasal-nitric-oxide-in-chronic-rhinosinusitis-patients-with-nasal-polyps-in-primary-care
#1
M Frendo, K Hakansson, S Schwer, A T Ravn, H Meteran, C Porsbjerg, V Backer, C von Buchwald
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated with lower airway disease. However, only few studies of CRSwNP from outside secondary/tertiary care centres have been published. We recently reported an asthma frequency of 44% and 65% in primary and secondary care patients respectively. Therefore, we hypothesise that inflammation of the lower airways could be present in all CRSwNP patients, even without asthma. Here, we assessed the degree of lower and upper airway inflammation using exhaled and nasal nitric oxide (NO) in primary care CRSwNP patients with and without asthma...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166385/evidence-of-molting-and-the-function-of-rock-nosing-behavior-in-bowhead-whales-in-the-eastern-canadian-arctic
#2
Sarah M E Fortune, William R Koski, Jeff W Higdon, Andrew W Trites, Mark F Baumgartner, Steven H Ferguson
Bowhead whales (Balaena mysticetus) have a nearly circumpolar distribution, and occasionally occupy warmer shallow coastal areas during summertime that may facilitate molting. However, relatively little is known about the occurrence of molting and associated behaviors in bowhead whales. We opportunistically observed whales in Cumberland Sound, Nunavut, Canada with skin irregularities consistent with molting during August 2014, and collected a skin sample from a biopsied whale that revealed loose epidermis and sloughing...
2017: PloS One
https://www.readbyqxmd.com/read/29166080/continuum-balances-from-extended-hamiltonian-dynamics
#3
Giulio G Giusteri, Paolo Podio-Guidugli, Eliot Fried
The classical procedure devised by Irving and Kirkwood in 1950 and completed slightly later by Noll produces counterparts of the basic balance laws of standard continuum mechanics starting from an ordinary Hamiltonian description of the dynamics of a system of material points. Post-1980 molecular dynamics simulations of the time evolution of such systems use extended Hamiltonians such as those introduced by Andersen, Nosé, and Parrinello and Rahman. The additional terms present in these extensions affect the statistical properties of the system so as to capture certain target phenomenologies that would otherwise be beyond reach...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29165896/investigation-of-the-abnormal-nasal-aerodynamics-and-trigeminal-functions-among-empty-nose-syndrome-patients
#4
Chengyu Li, Alexander A Farag, Guillermo Maza, Sam McGhee, Michael A Ciccone, Bhakthi Deshpande, Edmund A Pribitkin, Bradley A Otto, Kai Zhao
BACKGROUND: Abnormal nasal aerodynamics or trigeminal functions have been frequently implicated in the symptomology of empty nose syndrome (ENS), yet with limited evidence. METHODS: Individual computed tomography (CT)-based computational fluid dynamics (CFD) was applied to 27 ENS patients to simulate their nasal aerodynamics and compared with 42 healthy controls. Patients' symptoms were confirmed with Empty Nose Syndrome 6-item Questionnaire (ENS6Q), 22-item Sino-Nasal Outcome Test (SNOT-22), and Nasal Obstruction Symptom Evaluation (NOSE) scores...
November 22, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29165895/adaptation-and-validation-of-the-turkish-version-of-the-nasal-obstruction-symptom-evaluation-scale
#5
Ozlem Onerci Celebi, Ela Araz Server, Ozgur Yigit, Ecem Sevim Longur
BACKGROUND: The Nasal Obstruction Symptom Evaluation (NOSE) scale is a questionnaire used to assess the quality of life in patients with nasal obstruction. The aim of this study was to validate the Turkish translation of the NOSE questionnaire. METHODS: The NOSE questionnaire was translated into Turkish and then back to English. Fifty patients with septal deviation leading to nasal obstruction and 50 healthy subjects without any nasal complaints and pathologies were recruited into the study...
November 22, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29165576/timing-of-first-respiratory-virus-detections-in-infants-a-community-based-birth-cohort-study
#6
Mohinder Sarna, Robert S Ware, Stephen B Lambert, Theo P Sloots, Michael D Nissen, Keith Grimwood
Background: Determining timing of first virus detection episodes (fVDEs) for different respiratory viruses in infants identifies risk periods and informs preventive interventions, including vaccination. We describe the ages and nature of fVDEs in an infant birth cohort, and explore factors associated with increased odds of symptomatic fVDEs. Methods: The Observational Research in Childhood Infectious Diseases (ORChID) study is a community-based birth cohort describing acute respiratory infections in infants until their second birthday...
November 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29165028/super-recognition-in-development-a-case-study-of-an-adolescent-with-extraordinary-face-recognition-skills
#7
Rachel J Bennetts, Joseph Mole, Sarah Bate
Face recognition abilities vary widely. While face recognition deficits have been reported in children, it is unclear whether superior face recognition skills can be encountered during development. This paper presents O.B., a 14-year-old female with extraordinary face recognition skills: a "super-recognizer" (SR). O.B. demonstrated exceptional face-processing skills across multiple tasks, with a level of performance that is comparable to adult SRs. Her superior abilities appear to be specific to face identity: She showed an exaggerated face inversion effect and her superior abilities did not extend to object processing or non-identity aspects of face recognition...
November 22, 2017: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29165025/familiar-face-priming-the-role-of-second-order-configuration-and-individual-face-recognition-abilities
#8
Marlena L Itz, Stefan R Schweinberger, Jürgen M Kaufmann
The role of second-order configuration-that is, metric distances between individual features-for familiar face recognition has been the subject of debate. Recent reports suggest that better face recognition abilities coincide with a weaker reliance on shape information for face recognition. We examined contributions of second-order configuration to familiar face repetition priming by manipulating metric distances between facial features. S1 comprised familiar face primes as either: unaltered, with increased or decreased interocular distance, with increased or decreased distance between nose and mouth; or a different familiar face (unprimed)...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/29162783/impact-of-macroprolactin-on-galactorrhea-and-the-rate-of-patients-possibly-affected-by-macroprolactin
#9
Kohzo Aisaka, Fujiko Tsuchiya, Masami Sueta, Kana Itabashi, Sayaka Nose, Akiko Hasegawa, Seiichiro Obata, Haruko Hiraike, Tetsuhiko Yokoyama
The clinical influence of macroprolactin (MPRL) is not clearly understood and the rate of patients potentially affected by MPRL is unknown. We investigated the influence of MPRL on the onset of galactorrhea and estimated the rate of patients with a proportion of MPRL fraction that may possibly affect galactorrhea. Data of patients with obstetric or gynecological symptoms who had undergone PRL fractionation testing were retrospectively analyzed. To evaluate factors influencing galactorrhea, a multivariate logistic regression analysis was performed and the adjusted odds ratios of MPRL for galactorrhea were calculated...
November 22, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29162159/pulsed-electron-avalanche-knife-peak-plasmablade%C3%A2-in-pacemaker-and-defibrillator-procedures
#10
Elif Kaya, Matthias Totzeck, Tienush Rassaf
BACKGROUND: The pulsed electron avalanche knife (PEAK) PlasmaBlade™ is an innovative electrosurgical device that uses a novel technology to cut tissues. It has been proven to be safe and feasible in ear, nose, and throat surgery, but there are only limited data concerning the use of PlasmaBlade™ instead of conventional electrocautery in cardiac implantable electronic device (CIED) procedures except for generator replacements. METHODS: We conducted a retrospective, single-center study with patients undergoing CIED surgery at our center between December 2015 and March 2017 and evaluate the feasibility and the clinical outcome of the PlasmaBlade™...
November 21, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29160343/the-effect-of-hard-tissue-surgical-changes-on-soft-tissue-displacement-a-pilot-cbct-study
#11
Leonardo Koerich, Daniel Paludo Brunetto, Eduardo Terumi Blatt Ohira
INTRODUCTION: This pilot study had as main objective to test the reliability of a new method to evaluate orthognathic surgery outcomes and also, to understand the effect of hard tissue changes on soft tissue displacement. METHODS: The sample consisted of eight patients that underwent bimaxillary advancement and had CBCT at two time points (before surgery and 6-8 months follow-up). Voxel-based cranial base superimposition was used to register the scans. A different technique of iterative closest point (ICP) was used to measure and correlate the changes...
September 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/29160150/electrocardiogram-screening-in-children-with-congenital-sensorineural-hearing-loss-prevalence-and-follow-up-of-abnormalities
#12
Zainab Farzal, Jonathan Walsh, Faisal I Ahmad, Jason Roberts, Sunita J Ferns, And Carlton J Zdanski
Objective The purpose is to determine the prevalence of electrocardiogram (ECG) abnormalities, including borderline and prolonged QT, among screened children with sensorineural hearing loss (SNHL) and to analyze their subsequent medical workup. Study Design Institutional Review Board-approved case series with chart review. Setting Tertiary academic center. Subjects and Methods Cases from 1996 to 2014 involving pediatric patients (N = 1994) with SNHL were analyzed. Abnormal ECGs were categorized as borderline/prolonged QT or other...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29159447/transcriptome-sequencing-of-the-long-nosed-bandicoot-perameles-nasuta-reveals-conservation-and-innovation-of-immune-genes-in-the-marsupial-order-peramelemorphia
#13
Katrina M Morris, Haylee J Weaver, Denis O'Meally, Marion Desclozeaux, Amber Gillett, Adam Polkinghorne
Bandicoots are omnivorous marsupials of the order Peramelemorphia. Conservation concerns and their unique biological characteristics suggest peramelomorphs are worthy research subjects, but knowledge of their genetics and immunology has lagged behind that of other high-profile marsupials. Here, we characterise the transcriptome of the long-nose bandicoot (Perameles nasuta), the first high-throughput data set from any peramelomorph. We investigate the immune gene repertoire of the bandicoot, with a focus on key immune gene families, and compare to previously characterised marsupial and mammalian species...
November 20, 2017: Immunogenetics
https://www.readbyqxmd.com/read/29158359/are-cocaine-seeking-habits-necessary-for-the-development-of-addiction-like-behavior-in-rats
#14
Bryan F Singer, Monica Fadanelli, Alex B Kawa, Terry E Robinson
Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs. By their design, such procedures often produce behavior controlled by stimulus-response (S-R) habits. This has supported the notion of addiction as a "drug habit", and has led to considerable advances in our understanding of the neurobiological basis of such behavior. However, for addicts to procure drugs, like cocaine, often requires considerable ingenuity and flexibility in seeking behavior, which, by definition, precludes the development of habits...
November 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29157983/blockade-of-nmda-receptors-blocks-the-acquisition-of-cocaine-conditioned-approach-in-rats
#15
Ewa Galaj, Neal Seepersad, Zena Dakmak, Robert Ranaldi
Conditioned stimuli (CSs) exert motivational effects on both adaptive and pathological reward-related behaviors, including drug taking and seeking. We developed a paradigm that allows us to investigate the neuropharmacology by which previously neutral stimuli acquire the capacity to function as CSs and elicit (intravenous) cocaine conditioned approach and used this paradigm to test the role of NMDA receptor stimulation in the acquisition of cocaine conditioned approach. Rats were injected systemically with the NMDA receptor antagonist, MK-801, before the start of 4 consecutive conditioning sessions, each of which consisted of 20 randomly presented light/tone (CS) presentations paired with cocaine infusion contingent upon nose pokes...
November 17, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29157878/-septoplasty-during-primary-unilateral-cleft-lip-repair
#16
J Saboye
Primary repair of cleft lip and palate has become a nasal and lip repair. In the aim to improve our nasal results on symmetry we perform an extensive septoplasty to put the nose in a good shape and a median axis. This septoplasty without resection of cartilage does not cause growth disorders to the nose and it promotes maxillary growth by improving early nasal breathing. It can prevent secondary rhinoplasty, source of new scars (externally, fork). But rhinoplasty will increase the incidence of scar contraction, thus shaping with a nasal conformer is essential...
November 17, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29156597/different-ways-to-apply-a-measurement-instrument-of-e-nose-type-to-evaluate-ambient-air-quality-with-respect-to-odour-nuisance-in-a-vicinity-of-municipal-processing-plants
#17
REVIEW
Bartosz Szulczyński, Tomasz Wasilewski, Wojciech Wojnowski, Tomasz Majchrzak, Tomasz Dymerski, Jacek Namieśnik, Jacek Gębicki
This review paper presents different ways to apply a measurement instrument of e-nose type to evaluate ambient air with respect to detection of the odorants characterized by unpleasant odour in a vicinity of municipal processing plants. An emphasis was put on the following applications of the electronic nose instruments: monitoring networks, remote controlled robots and drones as well as portable devices. Moreover, this paper presents commercially available sensors utilized in the electronic noses and characterized by the limit of quantification below 1 ppm v/v, which is close to the odour threshold of some odorants...
November 19, 2017: Sensors
https://www.readbyqxmd.com/read/29155535/an-interesting-case-of-oral-inverted-ductal-papilloma
#18
Natasha Berridge, Mahesh Kumar
Ductal papillomas are rare benign papillary tumours of the minor salivary glands. Previously they have been classified into three subtypes: inverted ductal papilloma (IDP), sialadenoma papilliferum and intraductal papilloma. The oral inverted ductal papilloma is the least common of these lesions, with 48 cases reported to date in a search of the English-language literature. We describe an interesting case of oral IDP and highlight the pertinent clinical and histopathological features. Importantly, unlike the histologically similar inverted papilloma (IP) of the nose and paranasal sinuses, oral IDP is a completely benign lesion and is not associated with malignant change...
December 2016: Dental Update
https://www.readbyqxmd.com/read/29151862/profiling-the-immunome-of-little-brown-myotis-provides-a-yardstick-for-measuring-the-genetic-response-to-white-nose-syndrome
#19
Michael E Donaldson, Christina M Davy, Craig K R Willis, Scott McBurney, Allysia Park, Christopher J Kyle
White-nose syndrome (WNS) has devastated populations of hibernating bats in eastern North America, leading to emergency conservation listings for several species including the previously ubiquitous little brown myotis (Myotis lucifugus). However, some bat populations near the epicenter of the WNS panzootic appear to be stabilizing after initial precipitous declines, which could reflect a selective immunogenetic sweep. To investigate the hypothesis that WNS exerts significant selection on the immunome of affected bat populations, we developed a novel, high-throughput sequence capture assay targeting 138 adaptive, intrinsic, and innate immunity genes of putative adaptive significance, as well as their respective regulatory regions (~370 kbp of genomic sequence/individual)...
December 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/29150922/prospective-evaluation-of-a-nonsurgical-device-for-rhinoplasty
#20
M A Deggeller, D Holzmann, M B Soyka
BACKGROUND: Rhinoplasty represents one of the most challenging and frequently performed procedures in plastic surgery and non-surgical rhinoplasty is rarely considered. The aim of this study was to investigate whether the Nasella Nose Former (NNF), a newly developed non-surgical rhinoplasty device, could improve objective and subjective results following surgical rhinoplasty and even correct the shape of the nose without any surgery at all. METHODOLOGY: In this prospective, monocentric, two-armed, non-blinded randomized, controlled clinical trial, a total of 43 participants were included...
November 18, 2017: Rhinology
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