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https://www.readbyqxmd.com/read/28231578/biomarkers-for-hearing-dysfunction-facts-and-outlook
#1
Lukas Rüttiger, Ulrike Zimmermann, Marlies Knipper
In medicine, biomarkers are a metric for disease state. More generally, a biomarker is anything that can be used as an indicator for a particular disease state or any physiological state of an organism. Here, we introduce functional and molecular biomarkers that are useful for categorizing defined subtypes of hearing disorder, which can help to selectively trace a particular dysfunction of the inner ear and the auditory pathway to disease.
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231370/significance-of-imaging-in-the-diagnosis-of-olfactory-disorder
#2
Teemu Harju, Markus Rautiainen, Ilkka Kivekäs
The aim of this retrospective analysis was to examine olfactory disorders among the patients in the Ear, Nose, and Throat Clinic of Tampere University Hospital, Finland, from 2001 to 2011, and to evaluate the necessity of imaging in the examination of patients with olfactory disorders. Charts of 143 consecutive patients with a primary olfactory disorder were examined, and 69 patients who had undergone the necessary testing were included in the study. The most common causes of olfactory disorder were upper respiratory infection (23%), chronic rhinosinusitis (19%), head trauma (17%), and allergic or nonallergic rhinitis (6%)...
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28231295/the-pathogens-profile-in-children-with-otitis-media-with-effusion-and-adenoid-hypertrophy
#3
G P Buzatto, E Tamashiro, J L Proenca-Modena, T H Saturno, M C Prates, T B Gagliardi, L R Carenzi, E T Massuda, M A Hyppolito, F C P Valera, E Arruda, W T Anselmo-Lima
OBJECTIVES: To evaluate the presence of viruses and bacteria in middle ear and adenoids of patients with and without otitis media with effusion (OME). METHODS: Adenoid samples and middle ear washes (MEW) were obtained from children with OME associated with adenoid hypertrophy undergoing adenoidectomy and tympanostomy, and compared to those obtained from patients undergoing cochlear implant surgery, as a control group. Specific DNA or RNA of 9 respiratory viruses (rhinovirus, influenza virus, picornavirus, syncytial respiratory virus, metapneumovirus, coronavirus, enterovirus, adenovirus and bocavirus) and 5 bacteria (S...
2017: PloS One
https://www.readbyqxmd.com/read/28231274/early-skin-to-skin-contact-after-cesarean-section-a-randomized-clinical-pilot-study
#4
Martina Kollmann, Lisa Aldrian, Anna Scheuchenegger, Eva Mautner, Sereina A Herzog, Berndt Urlesberger, Reinhard B Raggam, Uwe Lang, Barbara Obermayer-Pietsch, Philipp Klaritsch
OBJECTIVE: Early bonding by skin-to-skin contact (SSC) has been demonstrated to be beneficial for mothers and newborns following vaginal delivery. The aim of this study was to investigate the impact of intraoperative bonding (early SSC) after cesarean section on neonatal adaptation, maternal pain and stress response. STUDY DESIGN: This prospective, randomized-controlled pilot study was performed at a single academic tertiary hospital (Department of Obstetrics and Gynecology, Medical University of Graz, Austria) between September 2013 and January 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28230804/calcium-intake-and-nutritional-adequacy-in-spanish-children-the-aniva-study
#5
Nuria Rubio-López, Agustín Llopis-González, María Morales-Suárez-Varela
Calcium is an important nutrient for child development. The main objective of this study was to assess calcium intake and its adequacy with dietary reference intake (DRI) in Spanish children. The ANIVA (Antropometría y Nutrición Infantil de Valencia) study is a descriptive cross-sectional study. During two academic years 2013-2014 and 2014-2015, 1176 schoolchildren aged 6-9 years were selected from 14 primary schools in Valencia (Spain). Three-day food records were used to assess dietary intake, completed by parents/guardian...
February 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28230212/establishment-of-planar-cell-polarity-is-coupled-to-regional-cell-cycle-exit-and-cell-differentiation-in-the-mouse-utricle
#6
Xiaoyu Yang, Xiaoqing Qian, Rui Ma, Xinwei Wang, Juanmei Yang, Wenwei Luo, Ping Chen, Fanglu Chi, Dongdong Ren
Sensory hair cells are coordinately oriented within each inner ear sensory organ to exhibit a particular form of planar cell polarity (PCP) necessary for mechanotransduction. However, the developmental events associated with establishing PCP in the vestibule are unclear, hindering data interpretation and employment of the vestibule for PCP studies. Herein, we investigated PCP of the mouse vestibular organs. We further characterised cell cycle exit, cell differentiation, and PCP establishment in the utricle...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229060/vitamin-d-levels-in-children-with-adenotonsillar-hypertrophy-and-otitis-media-with-effusion
#7
Alimohamad Asghari, Zohreh Bagheri, Maryam Jalessi, Mohammad Mahdi Salem, Elahe Amini, Sahand GhalehBaghi, Sepideh Bakhti
INTRODUCTION: Vitamin D has been suggested to play a considerable role in the function of the immune system in various infectious, inflammatory, and autoimmune conditions. Otitis media with effusion (OME), defined as the presence of non-purulent fluid within the middle ear without signs or symptoms of suppurative otitis media, has a number of inflammatory predisposing factors. This study was designed to explore the association between vitamin D deficiency and OME. MATERIALS AND METHODS: In this cross-sectional study, 74 children aged 2-7 years with an obstructive indication for adenotonsillectomy were included...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28229059/comparison-of-fluoroplastic-causse-loop-piston-and-titanium-soft-clip-in-stapedotomy
#8
Mohammad Faramarzi, Nafiseh Gilanifar, Sareh Roosta
INTRODUCTION: Different types of prosthesis are available for stapes replacement. Because there has been no published report on the efficacy of the titanium soft-clip vs the fluoroplastic Causse loop Teflon piston, we compared short-term hearing results of both types of prosthesis in patients who underwent stapedotomy due to otosclerosis. MATERIALS AND METHODS: A total of 57 ears were included in the soft-clip group and 63 ears were included in the Teflon-piston group...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28229057/meatoplasty-in-canal-wall-down-surgery-our-experience-and-literature-review
#9
Faramarz Memari, Mojtaba Maleki Delarestaghi, Parisa Mir, Mohammad GolMohammadi, Ehsan Shams Koushki
INTRODUCTION: Meatoplasty is the final and essential step in performing effective canal wall down surgery for chronic otitis media. In this article we review some previous techniques and discuss our preferred method. MATERIALS AND METHODS: In this observational case series study, we used this technique in 53 patients (28 male and 25 female) between January 2005 and January 2008. Our survey was completed in 31 patients. RESULTS: Twenty-six patients (83...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28229056/experimental-visualization-of-labyrinthine-structure-with-optical-coherence-tomography
#10
Saleh Mohebbi, Marjan Mirsalehi, Lüder-Alexander Kahrs, Tobias Ortmaier, Thomas Lenarz, Omid Majdani
INTRODUCTION: Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones. MATERIALS AND METHODS: Three fresh human explanted temporal bones were trimmed, chemically decalcified with ethylenediaminetetraacetic acid (EDTA), and mechanically drilled under visual control using OCT in order to reveal the remaining bone shell...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28228581/spaceflight-induced-synaptic-modifications-within-hair-cells-of-the-mammalian-utricle
#11
David R Sultemeier, Kristel R Choy, Felix E Schweizer, Larry F Hoffman
Exposure to the microgravity conditions of spaceflight alleviates the load normally imposed by the Earth's gravitational field upon the inner ear utricular epithelia. Previous ultrastructural investigations showed that spaceflight induced an increase in synapse density within hair cells of the rat utricle. However, the utricle exhibits broad physiologic heterogeneity across different epithelial regions, and it is unknown whether capabilities for synaptic plasticity generalize to hair cells across its topography...
February 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28227996/a-novel-approach-for-chewing-detection-based-on-a-wearable-ppg-sensor
#12
Vasileios Papapanagiotou, Christos Diou, Lingchuan Zhou, Janet van den Boer, Monica Mars, Anastasios Delopoulos, Vasileios Papapanagiotou, Christos Diou, Lingchuan Zhou, Janet van den Boer, Monica Mars, Anastasios Delopoulos, Janet van den Boer, Vasileios Papapanagiotou, Lingchuan Zhou, Anastasios Delopoulos, Monica Mars, Christos Diou
Monitoring of human eating behaviour has been attracting interest over the last few years, as a means to a healthy lifestyle, but also due to its association with serious health conditions, such as eating disorders and obesity. Use of self-reports and other non-automated means of monitoring have been found to be unreliable, compared to the use of wearable sensors. Various modalities have been reported, such as acoustic signal from ear-worn microphones, or signal from wearable strain sensors. In this work, we introduce a new sensor for the task of chewing detection, based on a novel photoplethysmography (PPG) sensor placed on the outer earlobe to perform the task...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227868/middle-and-inner-ear-modelling-from-microct-images-to-3d-reconstruction-and-coupling-of-models
#13
N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, A I Sakellarios, V Isailovic, D I Fotiadis, A Bibas, F Bohnke, G Ni, N Filipovic, G Rigas, N S Tachos
We present finite element (FE) modeling approaches of ear mechanics including 3-dimensional (3D) reconstruction of the human middle and inner ear. Specifically, we demonstrate a semi-automatic methodology for the 3D reconstruction of the inner ear structures, a FE harmonic response model of the middle ear to predict the stapes footplate frequency response, a 2D FE slice model of the cochlea for the coupled response at the micromechanical level for either acoustic or electrical excitation and a coupled FE middle ear model with a simplified cochlea box model to simulate the basilar membrane velocity in response to acoustic excitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227806/a-new-soft-material-based-in-the-ear-eeg-recording-technique
#14
Hao Dong, Paul M Matthews, Yike Guo, Hao Dong, Paul M Matthews, Yike Guo, Hao Dong, Paul M Matthews, Yike Guo
Long-term electroencephalogram (EEG) is important for seizure detection, sleep monitoring and etc. In-the- ear EEG device makes such recording robust to noise and privacy protected (invisible to other people). However, the state-of-art techniques suffer from various drawbacks such as customization for specific users, manufacturing difficulties and short life cycle. To address these issues, we proposed silvered glass silicone based in-the-ear electrode which can be manufactured using conventional compression moulding...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227803/ear-eeg-allows-extraction-of-neural-responses-in-challenging-listening-scenarios-a-future-technology-for-hearing-aids
#15
L Fiedler, J Obleser, T Lunner, C Graversen, L Fiedler, J Obleser, T Lunner, C Graversen, J Obleser, C Graversen, L Fiedler, T Lunner
Advances in brain-computer interface research have recently empowered the development of wearable sensors to record mobile electroencephalography (EEG) as an unobtrusive and easy-to-use alternative to conventional scalp EEG. One such mobile solution is to record EEG from the ear canal, which has been validated for auditory steady state responses and discrete event related potentials (ERPs). However, it is still under discussion where to place recording and reference electrodes to capture best responses to auditory stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227801/reference-configurations-for-ear-eeg-steady-state-responses
#16
Simon L Kappel, Christian B Christensen, Kaare B Mikkelsen, Preben Kidmose, Simon L Kappel, Christian B Christensen, Kaare B Mikkelsen, Preben Kidmose, Kaare B Mikkelsen, Preben Kidmose, Christian B Christensen, Simon L Kappel
Ear-EEG is a non-invasive EEG recording method, where EEG is recorded from electrodes placed in the ear. Ear-EEG could be implemented into hearing aids, and provide neurofeedback for e.g. objective hearing assessment through measurements of the auditory steady-state response. In cases where the objective is to measure a specific feature of an event-related potential, there will be a subject specific optimal reference configuration. This work presents a method for optimizing the reference configuration for steady-state type potentials...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227737/development-of-bone-conduction-mobile-phones-assessment-of-hearing-mechanisms-by-measuring-psychological-characteristics-and-acoustical-properties-in-the-outer-ear-canal
#17
Seiji Nakagawa, Takuya Hotehama, Kazuhito Ito, Tomohiro Inagaki, Seiji Nakagawa, Takuya Hotehama, Kazuhito Ito, Tomohiro Inagaki, Seiji Nakagawa, Tomohiro Inagaki, Kazuhito Ito, Takuya Hotehama
We have been developing novel mobile phones using bone conduction, with flat-panel loudspeakers that convey speech sound by vibrating the pinna. In bone conduction via the pinna, i.e., pinna conduction, it is thought that speech sounds are conveyed via both air- and bone-conduction pathways. To obtain useful information for further development of bone-conduction mobile phones, peripheral mechanisms of the pinna conduction need to be clarified. In this study, hearing thresholds, sound field in the outer ear canals, and vibrations of the inner wall of the outer ear canals were measured while normal-hearing participants used pinna-conduction mobile phones...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227655/development-of-a-snake-like-dexterous-manipulator-for-skull-base-surgery
#18
Suat Coemert, Anzhu Gao, John P Carey, Mattias F Traeger, Russell H Taylor, Tim C Lueth, Mehran Armand, Suat Coemert, Anzhu Gao, John P Carey, Mattias F Traeger, Russell H Taylor, Tim C Lueth, Mehran Armand, Anzhu Gao, Russell H Taylor, Mattias F Traeger, Mehran Armand, Suat Coemert, Tim C Lueth, John P Carey
Petrous apex lesions constitute considerable surgical challenges due to their location in the skull base and close relationship with critical structures such as inner ear, carotid arteries, facial nerves and jugular bulb. These lesions often cannot be treated completely with rigid tools due to the limited accessibility. We are aiming to develop a snake-like manipulator to assist surgeons with the infralabyrinthine treatment of petrous apex lesions with increased dexterity. This snake-like dexterous manipulator (SDM) with 3...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227574/automatic-sleep-stage-classification-using-ear-eeg
#19
Andreas Stochholm, Kaare Mikkelsen, Preben Kidmose, Andreas Stochholm, Kaare Mikkelsen, Preben Kidmose, Kaare Mikkelsen, Preben Kidmose, Andreas Stochholm
Sleep assessment is of great importance in the diagnosis and treatment of sleep disorders. In clinical practice this is typically performed based on polysomnography recordings and manual sleep staging by experts. This procedure has the disadvantages that the measurements are cumbersome, may have a negative influence on the sleep, and the clinical assessment is labor intensive. Addressing the latter, there has recently been encouraging progress in the field of automatic sleep staging [1]. Furthermore, a minimally obtrusive method for recording EEG from electrodes in the ear (ear-EEG) has recently been proposed [2]...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227548/driver-drowsiness-detection-using-the-in-ear-eeg
#20
Taeho Hwang, Miyoung Kim, Seunghyeok Hong, Kwang Suk Park, Taeho Hwang, Miyoung Kim, Seunghyeok Hong, Kwang Suk Park, Kwang Suk Park, Seunghyeok Hong, Miyoung Kim, Taeho Hwang
Driver drowsiness monitoring is one of the most demanded technologies for active prevention of severe road accidents. Electroencephalogram (EEG) and several peripheral signals have been suggested for the drowsiness monitoring. However, each type of signal has partial limitations in terms of either convenience or accuracy. Recent emerged concept of in-ear EEG raises expectations due to reduced obtrusiveness. It is yet unclear whether the in-ear EEG is effective enough for drowsiness detection in comparison with on-scalp EEG or peripheral signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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