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https://www.readbyqxmd.com/read/29684935/facial-asymmetry-based-age-group-estimation-role-in-recognizing-age-separated-face-images
#1
Muhammad Sajid, Imtiaz Ahmad Taj, Usama Ijaz Bajwa, Naeem Iqbal Ratyal
Face recognition aims to establish the identity of a person based on facial characteristics. On the other hand, age group estimation is the automatic calculation of an individual's age range based on facial features. Recognizing age-separated face images is still a challenging research problem due to complex aging processes involving different types of facial tissues, skin, fat, muscles, and bones. Certain holistic and local facial features are used to recognize age-separated face images. However, most of the existing methods recognize face images without incorporating the knowledge learned from age group estimation...
April 23, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29660516/molecular-cloning-and-characterization-of-c-1-tetrahydrofolate-c-1-thf-synthase-in-bombyx-mori-silkworm
#2
Meijun Chen, Jingjie Zhai, Yu Liu, Bin Xue, Jiahuan Hu, Xiaoyu Cheng, Jinxin Li, Jingsheng Hu, Bing Li
Folate metabolism pathway is mainly associated with syntheses of nucleic acids and proteins as well as DNA methylation and repair. Cytoplasmic C1 tetrahydrofolate (C1 -THF) synthase is a central enzyme in folate metabolism and plays an important role in C1 -THF conversion. The full-length sequence of silkworm (Bombyx mori) cytoplasmic C1 -THF synthase (BmC1 -THF synthase) gene including an open reading frame (ORF) of 932 amino acid residues was cloned. Phylogenetic analysis indicated that BmC1 -THF synthase shares 84% and 81% identity with C1 -THF synthase of Papilio Xuthus and Danaus plexippus, respectively...
April 13, 2018: Gene
https://www.readbyqxmd.com/read/29628462/-long-term-dietary-nitrite-and-nitrate-deficiency-causes-metabolic-syndrome-endothelial-dysfunction-and-cardiovascular-death-in-mice
#3
Mika Kina-Tanada, Mayuko Sakanashi, Akira Arasaki, Masato Tsutsui
Nitric oxide (NO) is synthesized not only from L-arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate. Green leafy vegetables are abundant in nitrate, however whether or not a deficiency in dietary nitrite/nitrate spontaneously causes disease remains to be clarified. In this study, we tested our hypothesis that long-term dietary nitrite/nitrate deficiency induces metabolic syndrome (MetS) in mice. To this end, we prepared a low nitrite/nitrate diet (LND) consisting of an amino acid-based low nitrite/nitrate chow in which the contents of L-arginine, fat, carbohydrates, protein, and energy were identical with a regular chow, and potable ultrapure water...
2018: Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
https://www.readbyqxmd.com/read/29622222/screening-of-critical-factors-influencing-the-efficient-hydrolysis-of-zeaxanthin-dipalmitate-in-an-adapted-in-vitro-digestion-model
#4
Xin Wen, Judith Hempel, Ralf M Schweiggert, Yuxiao Wang, Yuanying Ni, Reinhold Carle
As hydrolysis of carotenoid esters is believed to be highly efficient in vivo, their insufficient hydrolysis in in vitro-digestion models, particularly, regarding zeaxanthin diesters, is a current issue. Therefore, in this study, several factors related to the enzymatic hydrolysis were investigated in an adapted version of the standardized INFOGEST in vitro-digestion model, using zeaxanthin dipalmitate (ZDP) as a substrate. The results showed that pancreatic lipase was able to hydrolyze ZDP, whereas carboxyl ester lipase (CEL) substantially contributed to ZDP cleavage...
August 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29608919/morphological-properties-of-the-occlusion-body-of-adoxophyes-orana-granulovirus
#5
Keiko Tsuruta, Jörg T Wennmann, Yasuhisa Kunimi, Maki N Inoue, Madoka Nakai
A granulovirus (GV) that produces occlusion bodies (OBs) having an unusual morphology was found in an Adoxophyes sp. (Lepidoptera: Tortricidae) larva in a tea field in Miyazaki Prefecture, Japan. This isolate is considered to be a mutant of Adoxophyes orana granulovirus, designated AdorGV-M, because the nucleotide sequence of its genome is 99.7% identical to that of an English isolate of AdorGV, AdorGV-E. AdorGV-E produces typical ovocylindrical OBs that contain one occlusion-derived virus (ODV) per OB. On the other hand, AdorGV-M produces large cuboidal OBs, but the number of ODVs per OB was unknown...
March 30, 2018: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/29598829/depletion-of-dnmt1-in-differentiated-human-cells-highlights-key-classes-of-sensitive-genes-and-an-interplay-with-polycomb-repression
#6
Karla M O'Neill, Rachelle E Irwin, Sarah-Jayne Mackin, Sara-Jayne Thursby, Avinash Thakur, Ciske Bertens, Laura Masala, Jayne E P Loughery, Darragh G McArt, Colum P Walsh
BACKGROUND: DNA methylation plays a vital role in the cell, but loss-of-function mutations of the maintenance methyltransferase DNMT1 in normal human cells are lethal, precluding target identification, and existing hypomorphic lines are tumour cells. We generated instead a hypomorphic series in normal hTERT-immortalised fibroblasts using stably integrated short hairpin RNA. RESULTS: Approximately two-thirds of sites showed demethylation as expected, with one-third showing hypermethylation, and targets were shared between the three independently derived lines...
March 29, 2018: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/29575437/meal-composition-influences-postprandial-sensations-independently-of-valence-and-gustation
#7
T Pribic, H Vilaseca, A Nieto, L Hernandez, H Monrroy, C Malagelada, A Accarino, J Roca, F Azpiroz
BACKGROUND: Palatability of meals with identical composition has been shown to influence postprandial sensations. Our aim was to determine to what extent meal composition influences postprandial sensations independently of palatability. METHODS: Randomized, crossover, double-blind trial comparing the postprandial responses to a low-fat vs a high-fat test meal, with the same physical and organoleptic characteristics (taste, smell, texture, color, and temperature)...
March 25, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29567215/standards-and-labeling-of-milk-fat-and-spread-products-in-different-countries
#8
REVIEW
Chia-Lin Lee, Huei-Lin Liao, Wan-Chen Lee, Chao-Kai Hsu, Fwu-Chyn Hsueh, Jyh-Quan Pan, Chih-Hsuan Chu, Chieh-Ting Wei, Ming-Ju Chen
In the present paper, we provide comprehensive information related to labeling claims and standards of identity of milk fat and spread products. By reviewing the standards and regulations for dairy and non-dairy fat products, Codex Alimentarius and several other countries have clearly specified these products and set the requirements for use of the product name to prevent misleading or confusing the consumers. Generally, for the milkfat products, the fat in the products should be exclusively from milk and/or the products obtained from milk...
April 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29560930/gene-expression-signature-of-obesity-in-monozygotic-twins
#9
Francesc Font-Clos, Stefano Zapperi, Caterina A M La Porta
OBJECTIVE: Observational studies suggest that obesity might have a Mendelian origin, but it is not clear if gene expression patterns observed in obese subjects are secondary to genetic traits or not. 
 Approach: Here we test a transcriptomic signature of obesity previously identified by our group
 on a large cohort of twin subjects (TwinsUK). 
 Main results: The results show that the signature correlates strongly both with the body mass index (BMI) and fat mass...
March 21, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29545365/single-cell-rna-seq-reveals-the-transcriptional-landscape-and-heterogeneity-of-aortic-macrophages-in-murine-atherosclerosis
#10
Clément Cochain, Ehsan Vafadarnejad, Panagiota Arampatzi, Pelisek Jaroslav, Holger Winkels, Klaus Ley, Dennis Wolf, Antoine-Emmanuel Saliba, Alma Zernecke
<u>Rationale:</u> It is assumed that atherosclerotic arteries contain several macrophage subsets endowed with specific functions. The precise identity of these subsets is poorly characterized as they ha ve been defined by the expression of a restricted number of markers. <u>Objective:</u> We have applied single-cell RNA-seq as an unbiased profiling strategy to interrogate and classify aortic macrophage heterogeneity at the single-cell level in atherosclerosis. <u>Methods and Results:</u> We performed single-cell RNA sequencing of total aortic CD45+ cells extracted from the non-diseased (chow fed) and atherosclerotic (11 weeks of high fat diet) aorta of Ldlr-/- mice...
March 15, 2018: Circulation Research
https://www.readbyqxmd.com/read/29544769/extracellular-matrix-dynamics-during-mesenchymal-stem-cells-differentiation
#11
REVIEW
Thais Assis-Ribas, Maria Fernanda Forni, Sheila Maria Brochado Winnischofer, Mari Cleide Sogayar, Marina Trombetta-Lima
Mesenchymal stem cells (MSCs) are stromal cells that display self-renewal and multipotent differentiation capacity. The repertoire of mature cells generated ranges but is not restricted to: fat, bone and cartilage. Their potential importance for both cell therapy and maintenance of in vivo homeostasis is indisputable. Nonetheless, both their in vivo identity and use in cell therapy remain elusive. A drawback generated by this fact is that little is known about the MSC niche and how it impacts differentiation and homeostasis maintenance...
March 12, 2018: Developmental Biology
https://www.readbyqxmd.com/read/29539415/err%C3%AE-preserves-brown-fat-innate-thermogenic-activity
#12
Maryam Ahmadian, Sihao Liu, Shannon M Reilly, Nasun Hah, Weiwei Fan, Eiji Yoshihara, Pooja Jha, C Daniel De Magalhaes Filho, Sandra Jacinto, Andrew V Gomez, Yang Dai, Ruth T Yu, Christopher Liddle, Annette R Atkins, Johan Auwerx, Alan R Saltiel, Michael Downes, Ronald M Evans
Brown adipose tissue (BAT) adaptively transfers energy from glucose and fat into heat by inducing a gene network that uncouples mitochondrial electron transport. However, the innate transcription factors that enable the rapid adaptive response of BAT are unclear. Here, we identify estrogen-related receptor gamma (ERRγ) as a critical factor for maintaining BAT identity. ERRγ is selectively expressed in BAT versus WAT, in which, in the absence of PGC1α, it drives a signature transcriptional network of thermogenic and oxidative genes in the basal (i...
March 13, 2018: Cell Reports
https://www.readbyqxmd.com/read/29535934/prevalence-rates-of-adipoq-polymorphisms-in-indian-population-and-a-comparison-with-other-populations
#13
Sandhya Kiran Pemmasani, Rasika Raman, Anuradha Acharya
Introduction: The adiponectin gene, ADIPOQ , encodes an adipocytokine, known as adiponectin hormone. This hormone is known to be associated with insulin sensitization, fat metabolism, immunity, and inflammatory response. Polymorphisms in ADIPOQ gene lower the adiponectin levels, increasing the risk for diabetes and cardiovascular diseases. Aims: The study aimed to calculate the prevalence rates of ADIPOQ polymorphisms in Indian population and to compare those prevalence rates with that of other populations...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29524269/dermatomyositis-panniculitis-a-clinico-pathologic-and-immunohistochemical-study-of-18-cases
#14
Angel Santos Briz, Anaid Calle, Konstantinos Linos, Bruce Semans, Andrew Carlson, Omar P Sangüeza, Dieter Metze, Lorenzo Cerroni, José Luis Díaz-Recuero, Victoria Alegría-Landa, José Manuel Mascaró, Carmen Moreno, Jose Luis Rodríguez-Peralto, Luis Requena
BACKGROUND: Panniculitis occurring in dermatomyositis is uncommon, with only a few cases described in the literature, most of them as case reports. OBJECTIVE: This report describes the clinico-pathological and immunohistochemical findings in a series of 18 patients with panniculitis associated to dermatomyositis. METHODS: In each patient we collected the clinical data of the cutaneous lesions as well as the characteristic clinical and laboratory findings...
March 10, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29522773/effects-of-ovariectomy-and-exercise-training-intensity-on-energy-substrate-and-hepatic-lipid-metabolism-and-spontaneous-physical-activity-in-mice
#15
Marc A Tuazon, Sara C Campbell, Dylan J Klein, Sue A Shapses, Keith R Anacker, Tracy G Anthony, Mehmet Uzumcu, Gregory C Henderson
BACKGROUND: Menopause is associated with fatty liver, glucose dysregulation, increased body fat, and impaired bone quality. Previously, it was demonstrated that single sessions of high-intensity interval exercise (HIIE) are more effective than distance- and duration-matched continuous exercise (CE) on altering hepatic triglyceride (TG) metabolism and very-low density lipoprotein-TG (VLDL-TG) secretion. METHODS: Six weeks training using these modalities was examined for effects on hepatic TG metabolism/secretion, glucose tolerance, body composition, and bone mineral density (BMD) in ovariectomized (OVX) and sham-operated (SHAM) mice...
March 6, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29502519/identifying-prognostic-factors-for-conservative-treatment-outcomes-in-servicemen-with-chronic-exertional-compartment-syndrome-treated-at-a-rehabilitation-center
#16
Mariëtte Z Meulekamp, Peter van der Wurff, Alfred van der Meer, Cees Lucas
BACKGROUND: Chronic exertional compartment syndrome (CECS) is a condition of pain induced by exercise, and it is characterized by muscle swelling and impaired muscle function in the lower leg. Given the diversity in the diagnosis and treatment of CECS, it is desirable to determine variables pertaining to prognosis and recovery. The purpose of this study is to identify prognostic factors for conservative treatment outcomes in servicemen with CECS who were treated at a Military Rehabilitation Center...
November 28, 2017: Military Medical Research
https://www.readbyqxmd.com/read/29446671/unenhanced-mri-as-an-alternative-to-99m-tc-labeled-dimercaptosuccinic-acid-scintigraphy-in-the-detection-of-pediatric-renal-scarring
#17
Colbey W Freeman, Talissa A Altes, Patrice K Rehm, Eduard E de Lange, Luke Lancaster, John P Mugler, James T Patrie, Sean Corbett, Carlos Leiva-Salinas, Lucia Flors
OBJECTIVE: The purpose of this study was to determine whether unenhanced MRI without sedation is a feasible substitute for dimercaptosuccinic acid (DMSA) scintigraphy in the detection of renal scars in pediatric patients. SUBJECTS AND METHODS: Patients scheduled for 99mTc-labeled DMSA scintigraphy for assessment of possible renal scars were recruited to undergo unenhanced MRI (free-breathing fat-suppressed T2-weighted single-shot turbo spin-echo and T1-weighted gradient-echo imaging, 13 minutes' total imaging time)...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29423219/the-effect-of-protein-supplementation-on-body-muscle-mass-and-fat-mass-in-post-bariatric-surgery-a-randomized-controlled-trial-rct-study-protocol
#18
Sahar D Al-Shamari, Mohamed Aly ElSherif, Wahiba Hamid, Fahad Hanna
Background: Severe weight loss through means of bariatric surgery has been associated with loss of muscle mass due to lack of absorption of protein. The aim of this RCT is to investigate the effectiveness of protein supplementation in reducing the risk of developing protein malnutrition and muscle wasting in post-bariatric surgery patients in Qatar. Methods and analysis: The study was based at the Department of bariatric and metabolic surgery, Doha metropolitan and regional areas...
2018: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29417261/the-ratio-of-adscs-to-hsc-progenitors-in-adipose-tissue-derived-svf-may-provide-the-key-to-predict-the-outcome-of-stem-cell-therapy
#19
Mehmet Okyay Kilinc, Antonio Santidrian, Ivelina Minev, Robert Toth, Dobrin Draganov, Duong Nguyen, Elliot Lander, Mark Berman, Boris Minev, Aladar A Szalay
BACKGROUND: Stromal vascular fraction (SVF) represents an attractive source of adult stem cells and progenitors, holding great promise for numerous cell therapy approaches. In 2017, it was reported that 1524 patients received autologous SVF following the enzymatic digestion of liposuction fat. The treatment was safe and effective and patients showed significant clinical improvement. In a collaborative study, we analyzed SVF obtained from 58 patients having degenerative, inflammatory, autoimmune diseases, and advanced stage cancer...
February 7, 2018: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/29385484/life-cycle-efficiency-of-beef-production-ix-relationship-between-residual-feed-intake-of-heifers-and-cow-efficiency-ratios-based-on-harvest-carcass-and-wholesale-cut-weight-outputs
#20
M E Davis, P A Lancaster, J J Rutledge, L V Cundiff
Data were collected from 1953 through 1980 from identical and fraternal twin beef and dairy females born in 1953, 1954, 1959, 1964, and 1969, and from crossbred females born as singles in 1974, and their progeny. Numbers of dams that weaned at least 1 calf and were included in the first analysis were 37, 45, and 56 in the 1964, 1969, and 1974 data sets, respectively. Respective numbers of dams that weaned 3 calves and were included in a second analysis were 6, 8, 8, 22, 33, and 33 in the 1953, 1954, 1959, 1964, 1969, and 1974 experiments...
January 29, 2018: Journal of Animal Science
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