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https://www.readbyqxmd.com/read/29235554/morning-and-afternoon-appetite-and-gut-hormone-responses-to-meal-and-stress-challenges-in-obese-individuals-with-and-without-binge-eating-disorder
#1
S Carnell, C Grillot, T Ungredda, S Ellis, N Mehta, J Holst, A Geliebter
BACKGROUND: Eating late in the day is common, and stress can induce eating. Little is understood about how time of day and stress interact to affect appetite and thereby body weight. These may be particularly important influences in binge eaters, who tend to binge in the evening, and in response to stress. METHOD: Obese participants with (n=16) and without (n=16) Binge Eating Disorder (BED) participated in two identical test protocols beginning either in the morning or the afternoon (AM condition/PM condition), each following an 8 h fast...
December 13, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29234128/states-and-traits-of-neural-irregularity-in-the-age-varying-human-brain
#2
Leonhard Waschke, Malte Wöstmann, Jonas Obleser
Sensory representations, and thus human percepts, of the physical world are susceptible to fluctuations in brain state or "neural irregularity". Furthermore, aging brains display altered levels of neural irregularity. We here show that a single, within-trial, information-theoretic measure (weighted permutation entropy) captures neural irregularity in the human electroencephalogram as a proxy for both, trait-like differences between individuals of varying age, and state-like fluctuations that bias perceptual decisions...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29230105/growth-characteristics-of-methanomassiliicoccus-luminyensis-and-expression-of-methyltransferase-encoding-genes
#3
Lena Kröninger, Jacqueline Gottschling, Uwe Deppenmeier
DNA sequence analysis of the human gut revealed the presence a seventh order of methanogens referred to as Methanomassiliicoccales. Methanomassiliicoccus luminyensis is the only member of this order that grows in pure culture. Here, we show that the organism has a doubling time of 1.8 d with methanol + H2 and a growth yield of 2.4 g dry weight/mol CH4. M. luminyensis also uses methylamines + H2 (monomethylamine, dimethylamine, and trimethylamine) with doubling times of 2.1-2.3 d. Similar cell yields were obtained with equimolar concentrations of methanol and methylamines with respect to their methyl group contents...
2017: Archaea: An International Microbiological Journal
https://www.readbyqxmd.com/read/29229363/comparison-of-the-effects-of-flaxseed-oil-and-sunflower-seed-oil-consumption-on-serum-glucose-lipid-profile-blood-pressure-and-lipid-peroxidation-in-patients-with-metabolic-syndrome
#4
Atefeh Akrami, Farzad Nikaein, Siavash Babajafari, Shiva Faghih, Hassan Yarmohammadi
BACKGROUND: Metabolic syndrome (MetSyn) increases the risk of type II diabetes and morbidity and mortality due to cardiovascular diseases. Flaxseed oil (FO), as a functional food, is one of the major vegetal sources of essential omega-3 fatty acids. OBJECTIVE: This study aimed to compare the effects of consumption of FO and sunflower seed oil (SO) on lipid peroxidation and other symptoms of MetSyn. METHODS: This randomized controlled interventional trial was conducted on 60 volunteers aged 30 to 60 years who were diagnosed with MetSyn in Shiraz, Iran...
November 20, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29224869/effects-of-straw-processing-and-pen-overstocking-on-the-growth-performance-and-sorting-characteristics-of-diets-offered-to-replacement-holstein-dairy-heifers
#5
W K Coblentz, M S Akins, N M Esser, R K Ogden, S L Gelsinger
Our objectives were to evaluate the effects of pen-stocking density and straw processing on the growth performance, feed-bunk sorting behaviors, and hygiene of Holstein dairy heifers. Two corn silage-alfalfa haylage diets diluted with wheat straw were offered; diet composition was identical, except that one diet contained short (well-processed) straw (SS; 46.0% neutral detergent fiber, 12.9% crude protein, 60.7% total digestible nutrients, TDN), and the other long (poorly processed) straw (LS; 46.5% neutral detergent fiber, 12...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29223563/sexual-identity-adverse-childhood-experiences-and-suicidal-behaviors
#6
Kristen Clements-Nolle, Taylor Lensch, Amberlee Baxa, Christopher Gay, Sandra Larson, Wei Yang
PURPOSE: The objective of this study was to examine the influence of sexual identity and adverse childhood experiences (ACEs) on suicidal behaviors in a population-based sample of high school students. METHODS: A two-stage cluster random sampling design was used to recruit 5,108 students from 97 high schools. A total of 4,955 students (97%) provided information that allowed for classification of sexual identity into three groups: (1) lesbian, gay, or bisexual (LGB) (10%); (2) not sure (4...
December 6, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29218620/the-impact-of-injector-based-contrast-agent-administration-in-time-resolved-mra
#7
Johannes Budjan, Ulrike I Attenberger, Stefan O Schoenberg, Hubertus Pietsch, Gregor Jost
OBJECTIVES: Time-resolved contrast-enhanced MR angiography (4D-MRA), which allows the simultaneous visualization of the vasculature and blood-flow dynamics, is widely used in clinical routine. In this study, the impact of two different contrast agent injection methods on 4D-MRA was examined in a controlled, standardized setting in an animal model. METHODS: Six anesthetized Goettingen minipigs underwent two identical 4D-MRA examinations at 1.5 T in a single session...
December 7, 2017: European Radiology
https://www.readbyqxmd.com/read/29214236/characterization-of-byproducts-from-chemical-syntheses-of-oligonucleotides-containing-1-methyladenine-and-3-methylcytosine
#8
Qi Tang, Ang Cai, Ke Bian, Fangyi Chen, James C Delaney, Sravani Adusumalli, Alvin C Bach, Fatemeh Akhlaghi, Bongsup P Cho, Deyu Li
Oligonucleotides serve as important tools for biological, chemical, and medical research. The preparation of oligonucleotides through automated solid-phase synthesis is well-established. However, identification of byproducts generated from DNA synthesis, especially from oligonucleotides containing site-specific modifications, is sometimes challenging. Typical high-performance liquid chromatography (HPLC), mass spectrometry (MS), and gel electrophoresis methods alone are not sufficient for characterizing unexpected byproducts, especially for those having identical or very similar molecular weight (MW) to the products...
November 30, 2017: ACS Omega
https://www.readbyqxmd.com/read/29211516/racial-discrimination-and-low-household-education-predict-higher-body-mass-index-in-african-american-youth
#9
Devin S Nelson, Julia M Gerras, Kellye C McGlumphy, Erika R Shaver, Amaanat K Gill, Kamala Kanneganti, Tiwaloluwa A Ajibewa, Rebecca E Hasson
OBJECTIVE: The purpose of this study was to examine the relationships between environmental factors, including household education, community violence exposure, racial discrimination, and cultural identity, and BMI in African American adolescents. METHODS: A community-based sample of 198 African American youth (120 girls, 78 boys; ages 11-19 years) from Washtenaw County, Michigan, were included in this analysis. Violence exposure was assessed by using the Survey of Children's Exposure to Community Violence; racial discrimination by using the Adolescent Discrimination Distress Index; cultural identity by using the Acculturation, Habits, and Interests Multicultural Scale for Adolescents; and household education by using a seven-category variable...
December 6, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29199065/safety-evaluation-of-das-44406-6-soybeans-in-wistar-rats
#10
Zhiyong Qian, JoAnna Bultman, Sabitha Papineni, Ning He, Lisa Lanigan, Rod A Herman, Gordon C Hard
A 90-day in-country feeding trial in Wistar rats was conducted at Tianjin Laboratory in China to assess toxicity of diets containing DAS-44406-6 soybean meal. There were no treatment-related changes observed when compared with the non-GM isoline control groups but histopathologically, 2 of 10 high-dose females were reported to show kidney lesions. However, these findings contrasted with the absence of any treatment-related kidney lesions in 3 separate 90-day toxicity studies previously conducted in Sprague Dawley rats...
November 30, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29197119/fundamental-movement-skills-in-adolescents-secular-trends-from-2003-to-2010-and-associations-with-physical-activity-and-bmi
#11
Pertti Huotari, Pilvikki Heikinaro-Johansson, Anthony Watt, Timo Jaakkola
The aim of this study was to examine the secular trends in fundamental movement skills (FMS) among 15-16-year-old adolescents at two assessment points scheduled in 2003 and 2010, and to investigate the associations between FMS, physical activity (PA) and body mass index (BMI). In 2003, self-reported PA, weight and height, and objective FMS scores were collected from 2390 students and in 2010, similar data was generated from a second sample of 1346 students. FMS were assessed during both assessment phases using three identical objective FMS tests that were figure 8 dribbling, jumping laterally, and coordination track tests...
December 2, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29192516/knockdown-of-angiopoietin-like-2-mimics-the-benefits-of-intermittent-fasting-on-insulin-responsiveness-and-weight-loss
#12
Cécile Martel, Anthony Pinçon, Alexandre Maxime Bélanger, Xiaoyan Luo, Marc-Antoine Gillis, Olivia de Montgolfier, Nathalie Thorin-Trescases, Éric Thorin
Angiopoietin-like 2 (ANGPTL2) is an inflammatory adipokine linking obesity to insulin resistance. Intermittent fasting, on the other hand, is a lifestyle intervention able to prevent obesity and diabetes but difficult to implement and maintain. Our objectives were to characterize a link between ANGPTL2 and intermittent fasting and to investigate whether the knockdown of ANGPTL2 reproduces the benefits of intermittent fasting on weight gain and insulin responsiveness in knockdown and wild-type littermates mice...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29191164/weighted-likelihood-inference-of-genomic-autozygosity-patterns-in-dense-genotype-data
#13
Alexandra Blant, Michelle Kwong, Zachary A Szpiech, Trevor J Pemberton
BACKGROUND: Genomic regions of autozygosity (ROA) arise when an individual is homozygous for haplotypes inherited identical-by-descent from ancestors shared by both parents. Over the past decade, they have gained importance for understanding evolutionary history and the genetic basis of complex diseases and traits. However, methods to infer ROA in dense genotype data have not evolved in step with advances in genome technology that now enable us to rapidly create large high-resolution genotype datasets, limiting our ability to investigate their constituent ROA patterns...
December 1, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29172893/effect-of-age-sex-and-body-weight-on-the-serum-concentrations-of-cobalamin-and-folate-in-cats-consuming-a-consistent-diet
#14
Sarah A Hill, Nicholas J Cave, Sandra Forsyth
Objectives Multiple feline diseases involving the gastrointestinal tract, pancreas, liver and biliary tract are known to cause abnormal serum cobalamin and folate concentrations. Measuring the serum concentration of these vitamins can therefore be a helpful diagnostic tool. However, factors other than disease, in particular age, have also been suggested to have an effect on the serum concentration of cobalamin and folate. In previous studies, the dietary intake was not standardised, or even known, despite diet being the prinicpal source of both vitamins...
March 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29170811/triple-elastofibromas-located-in-the-supra-and-infrascapular-regions-a-case-report
#15
Cyprian Olchowy, Matías de Albert de Delás-Vigo, Manolo Perez, Nikaoly Ciriaco, Rosa Dominguez Oronoz
We report a case of triple elastofibromas located in the supra- and infrascapular regions. A 61-year-old female with a history of bilateral elastofibroma in the typical subscapular region (6 years before) was admitted for the evaluation of a left-sided suprascapular mass that she had first noted 3 months before. On physical examination, a firm, painless, mobile mass was palpated in the subcutaneous tissue. The patient had not observed any changes of the two known lesions over the past 6 years. The patient denied a family history of elastofibroma...
November 23, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29161094/the-effect-of-resistance-training-in-a-hypoxic-chamber-on-physical-performance-in-elite-rugby-athletes
#16
Brad Mayo, Cory Miles, Stacy Sims, Matthew Driller
Mayo, Brad, Cory Miles, Stacy Sims, and Matthew Driller. The effect of resistance training in a hypoxic chamber on physical performance in elite rugby athletes. High Alt Med Biol 00:000-000, 2017.-Limited research suggests that muscle adaptations may be enhanced through resistance training in a hypoxic environment. Seventeen professional rugby union athletes (age [mean ± SD], 24 ± 3 years; body mass, 98.7 ± 12.8 kg; and height, 188.9 ± 7.9 cm), performed 12 resistance training sessions over a 3-week period...
November 21, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29160925/effects-of-swaddled-and-traditional-tub-bathing-methods-on-crying-and-physiological-responses-of-newborns
#17
Sinem Yalnızoğlu Çaka, Duygu Gözen
PURPOSE: The purpose of this study was to examine the effects of two bathing methods on crying duration and physiological measurements of newborns. DESIGN AND METHODS: A randomized trial design was used in this study. The sample consisted of newborns (n = 80) who were admitted to neonatal intensive care unit of a university hospital located in a large city. The groups were determined as swaddled bathing (SB) (n = 40) and traditional tub bathing (TTB) (n = 40) by using random number table...
November 21, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29156513/production-and-characterization-of-keratinolytic-proteases-by-a-chicken-feather-degrading-thermophilic-strain-thermoactinomyces-sp-yt06
#18
Lin Wang, Yuting Qian, Yun Cao, Ying Huang, Zhizhou Chang, Hongying Huang
Thermoactinomyces sp. strain YT06 was isolated from poultry compost and observed to degrade integral chicken feathers at 60°C completely, resulting in the formation of 3.24 mg/mL of free amino acid from 50 mL of culture containing 10 g/L chicken feathers. Strain YT06 could grow and secret keratinase using feather as the only carbon and nitrogen sources without other supplement, but complementation of 10 g/L sucrose and 4 g/L NaNO₃ increased the production of the keratinolytic enzyme. The maximum protease activities obtained were 110 U/mL and keratinase were 42 U/mL...
November 21, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29154875/optimization-of-pegylation-reaction-time-and-molar-ratio-of-rhg-csf-toward-increasing-bioactive-potency-of-monopegylated-protein
#19
Jamila Behi, RymHassiki, Nadia Ben Said, Balkiss Bouhaouala-Zahar, Mohamed Lamine Benkhoud
PEGylation is one of the strategies used for enhancing in vivo residence time of recombinant human Granulocyte Colony-Stimulating Factor (rhG-CSF) and therefore reducing in dose frequency to better fit with patient comfort treatment. In this study, three methoxy polyethylene glycol propionaldehydes (mPEG- ALD) of 10, 20 and 30kDa MW were utilized to produce biologically active monoPEGylated rhG-CSF with enhanced molecular weight. PEGylation reactions were carried out at room temperature and pH 5.0 in the presence of cyanoborohydride and two mPEG-ALD: protein molar ratios (3:1 and 5:1)...
November 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29149718/coronary-risk-assessment-at-x-ray-dose-equivalent-ungated-chest-ct-results-of-a-multi-reader-study
#20
Michael Messerli, Lukas Hechelhammer, Sebastian Leschka, René Warschkow, Simon Wildermuth, Ralf W Bauer
OBJECTIVES: To determine the value of ultra-low dose chest CT with tin filtration for ordinal coronary artery calcium (CAC) risk scoring. METHODS: 50 patients were prospectively included and underwent clinical standard dose chest CT (1.8±0.7mSv) and ultra-low dose CT (0.13±0.01mSv). Four radiologists estimated presence and extent of CAC. RESULTS: Weighted kappa values for CAC were 0.76-0.97 in standard dose and 0.75-0.95 in ultra-low dose CT (p<0...
October 25, 2017: Clinical Imaging
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