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https://www.readbyqxmd.com/read/29903686/do-specialized-bariatric-multivitamins-lower-deficiencies-after-rygb
#1
Wendy Schijns, Lisanne T Schuurman, Alida Melse-Boonstra, Cees J H M van Laarhoven, Frits J Berends, Edo O Aarts
BACKGROUND: One of the side effects of bariatric surgery is the risk of vitamin and mineral deficiencies. Vitamin B12, vitamin D, folate, and iron deficiencies are especially common among Roux-en-Y gastric bypass patients. OBJECTIVE: To examine the effectiveness of a specialized multivitamin supplement for Roux-en-Y gastric bypass patients on deficiencies the first 3 years postoperatively, retrospectively in a large, prospectively collected cohort. SETTING: Large specialized bariatric hospital...
April 3, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29902892/-establishment-of-dna-identity-card-and-analysis-of-genetic-similarity-among-58-varieties-in-lonicera-japonica
#2
Feng-Jie Zhu, Shan-Shan Zhang, Yuan Yuan, Jun-Hui Zhou, Chao Jiang, Jian Yang, Juan Liu, Nian-Jun Yu, Lu-Qi Huang
A total of 58 varieties in Lonicera japonica from 20 producing areas were amplified by 22 pairs of SSR primers. Seven pairs of polymorphic primers were screened and their primers were used to establish DNA identity card and analyze genetic similarity.All the 58 varieties could be distinguished each other by the DNA identity card constituted by 7 pairs of core SSR primers.The genetic similarity coefficients of 58 varieties ranged from 0.366 7 to 0.916 7 by using PopGene32(vesion1.32). Furthermore, all the varieties consistency were classified into 4 groups and constructed an evaluation table according to cluster analysis by an un-weighted pair-group average method with arithmetic mean...
May 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29902162/youth-risk-behavior-surveillance-united-states-2017
#3
Laura Kann, Tim McManus, William A Harris, Shari L Shanklin, Katherine H Flint, Barbara Queen, Richard Lowry, David Chyen, Lisa Whittle, Jemekia Thornton, Connie Lim, Denise Bradford, Yoshimi Yamakawa, Michelle Leon, Nancy Brener, Kathleen A Ethier
PROBLEM: Health-risk behaviors contribute to the leading causes of morbidity and mortality among youth and adults in the United States. In addition, significant health disparities exist among demographic subgroups of youth defined by sex, race/ethnicity, and grade in school and between sexual minority and nonsexual minority youth. Population-based data on the most important health-related behaviors at the national, state, and local levels can be used to help monitor the effectiveness of public health interventions designed to protect and promote the health of youth at the national, state, and local levels...
June 15, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29901486/weight-loss-weight-loss-maintenance-and-cellular-aging-in-the-supporting-health-through-nutrition-and-exercise-shine-study
#4
Ashley E Mason, Frederick M Hecht, Jennifer J Daubenmier, David A Sbarra, Jue Lin, Patricia J Moran, Samantha G Schleicher, Michael Acree, Aric A Prather, Elissa S Epel
OBJECTIVE: To determine, within a weight-loss clinical trial for obesity, the impact of intervention arm, weight change, and weight-loss maintenance on telomere length (TL). METHODS: Adults (N=194) with a BMI between 30 and 45 were randomized to a 5.5-month weight-loss program with (n=100) or without (n=94) mindfulness training and identical diet-exercise guidelines. We assessed TL at baseline and 3, 6, and 12 months post-baseline in immune cell populations (primarily in peripheral blood mononuclear cells [PBMCs], but also in granulocytes and T and B lymphocytes)...
June 12, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29901025/on-complete-convergence-and-complete-moment-convergence-for-weighted-sums-of-%C3%AF-%C3%A2-mixing-random-variables
#5
Pingyan Chen, Soo Hak Sung
Let <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mi>r</mml:mi> <mml:mo>≥</mml:mo> <mml:mn>1</mml:mn> </mml:math> , <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mn>1</mml:mn> <mml:mo>≤</mml:mo> <mml:mi>p</mml:mi> <mml:mo><</mml:mo> <mml:mn>2</mml:mn> </mml:math> , and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mi>α</mml:mi> <mml:mo>,</mml:mo> <mml:mi>β</mml:mi> <mml:mo>></mml:mo> <mml:mn>0</mml:mn> </mml:math> with <mml:math xmlns:mml="http://www...
2018: Journal of Inequalities and Applications
https://www.readbyqxmd.com/read/29896265/comparison-of-efficacy-complications-and-tgf-%C3%AE-2-expression-between-dhs-and-pfna-in-elderly-patients-with-osteoporotic-femoral-intertrochanteric-fracture
#6
Rao Xu, Jiangying Ru, Feng Ji, Jie Liu, Yong Ji, Zhiquan Wu, Dai Shi
The aim of the present study was to compare the efficacy and complications of two fixation techniques, namely dynamic hip screw (DHS) and proximal femoral nail antirotation (PFNA), in the treatment of osteoporotic femoral intertrochanteric fracture in elderly patients, and to detect changes in transforming growth factor β2 (TGF-β2) expression in the two groups. A total of 100 elderly patients with femoral intertrochanteric fracture were randomly divided into two groups that were treated with either DHS or PFNA...
July 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29895288/registered-or-unregistered-levels-and-differentials-in-registration-and-certification-of-births-in-ghana
#7
Fidelia A A Dake, Kamil Fuseini
BACKGROUND: The birth of a child is a vital event that needs to be registered but this is not always the case as an estimated 40 million births go unregistered annually. Birth registration safeguards the basic rights of children and gives them an identity, citizenship/nationality and legal protection against violence, abuse and human rights violations. It is therefore necessary that all births are registered and even more critical that the registration of a birth is followed by the issuance of a birth certificate...
June 13, 2018: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/29894384/cumulative-plasma-hiv-burden-disparities-among-adults-in-hiv-care-implications-for-hiv-transmission-in-the-era-of-treatment-as-prevention
#8
Alison J Hughes, Amadeia Rector, Veronica Jimenez, Jon Brock, Susan Scheer
OBJECTIVE: To characterize disparities in cumulative plasma HIV burden in a sample of adults accessing HIV care in San Francisco, California. DESIGN: Observational cohort and supplemental HIV surveillance data. METHODS: Data from the San Francisco Medical Monitoring Project 2012-2014 cycles and HIV surveillance data were used to create an analytic cohort followed for two years. Matched HIV viral load (VL) test results from HIV surveillance were used to create five viral outcome measures: any unsuppressed VL (>200 copies/mL), any transmittable VL (>1500 copies/mL), person-time spent unsuppressed, person-time spent transmittable, and 2-year viremia copy-years, a measure of cumulative plasma HIV burden...
June 11, 2018: AIDS
https://www.readbyqxmd.com/read/29892352/effects-of-exposure-to-bodies-of-different-sizes-on-perception-of-and-satisfaction-with-own-body-size-two-randomized-studies
#9
Helen Bould, Rebecca Carnegie, Heather Allward, Emily Bacon, Emily Lambe, Megan Sapseid, Katherine S Button, Glyn Lewis, Andy Skinner, Matthew R Broome, Rebecca Park, Catherine J Harmer, Ian S Penton-Voak, Marcus R Munafò
Body dissatisfaction is prevalent among women and associated with subsequent obesity and eating disorders. Exposure to images of bodies of different sizes has been suggested to change the perception of 'normal' body size in others. We tested whether exposure to different-sized (otherwise identical) bodies changes perception of own and others' body size, satisfaction with body size and amount of chocolate consumed. In Study 1, 90 18-25-year-old women with normal BMI were randomized into one of three groups to complete a 15 min two-back task using photographs of women either of 'normal weight' (Body Mass Index (BMI) 22-23 kg m-2 ), or altered to appear either under- or over-weight...
May 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29891145/comparison-of-weighted-and-unweighted-network-analysis-in-the-case-of-a-pig-trade-network-in-northern-germany
#10
Kathrin Büttner, Joachim Krieter
The analysis of trade networks as well as the spread of diseases within these systems focuses mainly on pure animal movements between farms. However, additional data included as edge weights can complement the informational content of the network analysis. However, the inclusion of edge weights can also alter the outcome of the network analysis. Thus, the aim of the study was to compare unweighted and weighted network analyses of a pork supply chain in Northern Germany and to evaluate the impact on the centrality parameters...
August 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29866599/in-silico-prediction-of-t-and-b-cell-epitopes-in-pmpd-first-step-towards-to-the-design-of-a-chlamydia-trachomatis-vaccine
#11
Romina Cecilia Russi, Elian Bourdin, María Inés García, Carolina Melania I Veaute
BACKGROUND: Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane protein D (PmpD) is an attractive immunogen candidate as it is conserved among strains and it is target of neutralizing antibodies. However, its high molecular weight and its complex structure make it difficult to handle by recombinant DNA techniques. Our aim is to predict B-cell and T-cell epitopes of PmpD...
April 2018: Biomedical Journal
https://www.readbyqxmd.com/read/29864719/analysis-of-new-growth-promoting-black-market-products
#12
Oliver Krug, Andreas Thomas, Helle Malerød-Fjeld, Yvette Dehnes, Tim Laussmann, Ingo Feldmann, Albert Sickmann, Mario Thevis
Detecting agents allegedly or evidently promoting growth such as human growth hormone (GH) or growth hormone releasing peptides (GHRP) in doping controls has represented a pressing issue for sports drug testing laboratories. While GH is a recombinant protein with a molecular weight of 22 kDa, the GHRPs are short (3-6 amino acids long) peptides with GH releasing properties. The endogenously produced GH (22 kDa isoform) consists of 191 amino acids and has a monoisotopic molecular mass of 22,124 Da. Within this study, a slightly modified form of GH was discovered consisting of 192 amino acids carrying an additional alanine at the N-terminus, leading to a monoisotopic mass of 22,195 Da...
May 19, 2018: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/29859695/purification-characterization-and-gene-cloning-of-a-new-cold-adapted-%C3%AE-galactosidase-from-erwinia-sp-e602-isolated-in-northeast-china
#13
Yu Xia, Lili He, Jingjing Mao, Peipei Fang, Xiaoyuan Ma, Zhouping Wang
β-Galactosidases are widely used in industry for elimination of lactose from milk products. A new β-galactosidase was obtained from bacterial strain Erwinia sp. E602, newly isolated in northeast China. The enzyme was purified with the methods of ammonium sulfate fractionation, ion exchange, and gel filtration chromatography for further study of the enzymatic characteristics. The purified enzyme had a molecular weight of near 110 kDa. The optimum reaction temperature and pH of this enzyme was determined to be 40°C and 7...
May 30, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29851465/a-targeted-tubulysin-b-hydrazide-conjugate-for-the-treatment-of-lhrh-receptor-positive-cancers
#14
Jyoti Roy, Miranda Kaake, Madduri Srinivasarao, Philip S Low
The targeted delivery of chemotherapeutic agents to receptors that are over-expressed on cancer cells has become an attractive strategy to concentrate drugs in cancer cells while avoiding uptake by healthy cells. Luteinizing hormone-releasing hormone receptor (LHRH-R) has attracted considerable interest for this application, since LHRH-R is upregulated in ~86% of prostate cancers, ~80% of endometrial cancers, ~80% of ovarian cancers, and ~50% of breast cancers, but virtually absent from normal tissues. Although LHRH and related peptides have been used to deliver cytotoxic drugs to LHRH-R over-expressing cancer cells, they have suffered from off-target delivery of the therapeutic agents to the liver and kidneys...
May 31, 2018: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/29806707/thin-idealization-and-causal-attributions-mediate-the-association-between-culture-and-obesity-stereotypes-an-examination-of-chinese-and-american-adolescents
#15
Paul A Klaczynski, Wejdan S Felmban
Few studies have examined age or cultural differences in the stereotypes adolescents have of persons with obesity. The present research explored the hypotheses that American adolescents have more negative obesity stereotypes than Chinese adolescents and that the effects of culture are mediated by weight attributions and thin idealization. Participants (N = 335; 181 female; M age = 14.83 years, SD = 1.57 years) completed measures of thin idealization and causal attributions and made generalizations from and attributions of stereotypical personality characteristics to obese figures...
May 28, 2018: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/29795735/discrimination-against-obese-exercise-clients-an-experimental-study-of-personal-trainers
#16
Fabio Fontana, Jonathan Bopes, Seth Bendixen, Tyler Speed, Megan George, Mick Mack
The aim of the study was to compare exercise recommendations, attitudes, and behaviors of personal trainers toward clients of different weight statuses. Fifty-two personal trainers participated in the study. The data collection was organized into two phases. In phase one, trainers read a profile and watched the video displaying an interview of either an obese or an average-weight client. Profiles and video interviews were identical except for weight status. Then, trainers provided exercise recommendations and rated their attitude toward the client...
2018: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29795308/impact-of-race-on-dose-selection-of-molecular-targeted-agents-in-early-phase-oncology-trials
#17
Tomoya Yokota, Johanna Bendell, Patricia LoRusso, Takahiro Tsushima, Ved Desai, Hirotsugu Kenmotsu, Junichiro Watanabe, Akira Ono, Bhavani Murugesan, Joseph Silva, Tateaki Naito, Jonathan Greenberg, Prasanna Kumar, Yibin Wang, Takahiro Jikoh, Ryota Shiga, David M Hyman, Alan Loh Ho, David R Spriggs, Gary K Schwartz, Mrinal M Gounder
BACKGROUND: We examined the impact of race on the maximum tolerated doses (MTD) and final approved doses (FAD) of single-agent molecular-targeted agents (MTA) in North America/Europe (NA/EU) and Asia. METHODS: We searched PubMed and regulatory databases to identify targeted drugs approved globally and compared their FAD and MTD in corresponding phase I/II studies conducted separately in NA/EU and Asia. To evaluate this further, we conducted parallel, prospective, first-in-human studies of DS-7423, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumours in the US and Japan...
May 24, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29794566/effects-of-amplification-and-hearing-aid-experience-on-the-contribution-of-specific-frequency-bands-to-loudness
#18
Katie M Thrailkill, Marc A Brennan, Walt Jesteadt
OBJECTIVES: The primary aim of this study is to describe the effect of hearing aid amplification on the contribution of specific frequency bands to overall loudness in adult listeners with sensorineural hearing loss (SNHL). Results for listeners with SNHL were compared with results for listeners with normal hearing (NH) to evaluate whether amplification restores the normal perception of loudness for broadband sound. A secondary aim of this study is to determine whether the loudness perception of new hearing aid users becomes closer to normal over the first few months of hearing aid use...
May 22, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29787581/autologous-and-not-allogeneic-adipose-derived-stem-cells-improve-acute-burn-wound-healing
#19
Yu-Wei Chang, Yi-Chia Wu, Shu-Hung Huang, Hui-Min David Wang, Yur-Ren Kuo, Su-Shin Lee
Adipose-derived stem cells (ADSCs) transplant has been reported to be a potential treatment for burn wounds. However, the effects of autogenicity and allogenicity of ADSCs on burn wound healing have not been investigated and the method for using ADSCs still needs to be established. This study compared the healing effects of autologous and allogenic ADSCs and determined an optimal method of using ADSCs to treat acute burn wounds. Experiments were performed in 20 male Wistar rats (weight, 176-250 g; age, 6-7 weeks)...
2018: PloS One
https://www.readbyqxmd.com/read/29786871/gender-specific-effects-of-selection-for-drinking-in-the-dark-on-the-network-roles-of-coding-and-non-coding-rnas
#20
Ovidiu Dan Iancu, Alex Colville, Beth Wilmot, Robert Searles, Priscila Darakjian, Christina Zheng, Shannon McWeeney, Sunita Kawane, John C Crabbe, Pamela Metten, Denesa Oberbeck, Robert Hitzemann
BACKGROUND: Transcriptional differences between Heterogeneous stock (HS/NPT) mice and High Drinking in the Dark (HDID) selected mouse lines have previously been described based on microarray technology coupled with network based analysis (Iancu et al., 2013b). The network changes were reproducible in two independent selections and largely confined to two distinct network modules; in contrast differential expression appeared more specific to each selected line. The current study extends these results by utilizing RNA-Seq technology, allowing evaluation of the relationship between genetic risk and transcription of non-coding RNA; we additionally evaluate sex-specific transcriptional effects of selection...
May 22, 2018: Alcoholism, Clinical and Experimental Research
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