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Onodera’s Prognostic Nutritional Index

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https://www.readbyqxmd.com/read/29241167/nutritional-screening-and-clinical-outcome-in-hospitalized-patients-with-crohn-s-disease
#1
Azusa Takaoka, Masaya Sasaki, Naoko Nakanishi, Mika Kurihara, Akiko Ohi, Shigeki Bamba, Akira Andoh
BACKGROUND/AIMS: Hospitalized patients with Crohn's disease (CD) can develop severe nutritional deficits. However, the nutritional screening tools with the most utility for such patients are still unknown. METHODS: Nutritional status of 40 CD patients was assessed on admission using several screening tools and laboratory tests. Their validity was evaluated in relation to length of hospital stay (LOS) and intestinal resection. Receiver operating characteristic analysis was performed to predict prolonged LOS (≥28 days)...
December 14, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29157273/effect-of-daikenchuto-tj-100-on-gastrointestinal-symptoms-following-laparoscopic-colectomy-in-patients-with-colon-cancer-study-protocol-for-a-randomized-controlled-trial
#2
Nobuaki Hoshino, Kenji Kawada, Koya Hida, Toshiaki Wada, Ryo Takahashi, Mami Yoshitomi, Yoshiharu Sakai
BACKGROUND: Postoperative paralytic ileus can be a difficult complication for both surgeons and patients. Causes and treatments have been discussed for more than two centuries, but have not yet been fully resolved. Daikenchuto (TJ-100, DKT) is a traditional Japanese herbal medicine. Recently, some beneficial mechanisms of DKT to relieve paralytic ileus have been reported. DKT can suppress inflammation, increase intestinal blood flow, and accelerate bowel movements. Therefore, we have designed a randomized controlled trial to investigate the effects of DKT on postoperative gastrointestinal symptoms following laparoscopic colectomy in patients with left-sided colon cancer at a single institution...
November 21, 2017: Trials
https://www.readbyqxmd.com/read/29021438/factors-for-predicting-outcomes-among-non-hiv-patients-with-pulmonary-tuberculosis
#3
Toshinori Tsukahara, Nobuyuki Horita, Ken Tashiro, Kenjiro Nagai, Masaharu Shinkai, Masaki Yamamoto, Takashi Sato, Yu Hara, Hideyuki Nagakura, Yuji Shibata, Hiroki Watanabe, Kentaro Nakashima, Ryota Ushio, Akimichi Nagashima, Misako Ikeda, Atsuya Narita, Katsuhito Sasaki, Nobuaki Kobayashi, Makoto Kudo, Takeshi Kaneko
Background Onodera's Prognostic Nutritional Index (PNI), determined as "10× albumin (g/dL) + 0.005× lymphocyte count (/μL)," was originally designed to determine the risk of complications following gastrointestinal surgery. This single-center, retrospective observational study was designed to investigate whether or not the PNI can predict the treatment outcome. Methods We consecutively reviewed HIV-negative pulmonary tuberculosis adults in an isolation ward. Most patients were being treated with standard three- or four-drug regimens...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28814767/application-of-the-onodera-prognostic-nutrition-index-and-neutrophil-to-lymphocyte-ratio-in-risk-evaluation-of-postoperative-complications-in-crohn-s-disease
#4
Wei-Ming Kang, Chang-Zhen Zhu, Xiao-Xu Yang, Jian-Chun Yu, Zhi-Qiang Ma, Xin Ye, Kang Li, Dong Liu
This study aimed to investigate application of Onodera prognostic nutrition index (OPNI) and neutrophil-to-lymphocyte ratio (NLR) in evaluating risk of postoperative complications in Crohn's disease (CD). Clinical data of 108 postoperative CD patients in 9 years were respectively reviewed. OPNI and NLR were within 1 week preoperatively. Average OPNI was 38.8 ± 8.2 and significantly lower in patients with: CD type B3; lymphopenia; decreased haemoglobin, prealbumin, and albumin; and daily enteral nutrition <500 kcal/d...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28726497/prognosis-prediction-for-postoperative-esophageal-cancer-patients-using-onodera-s-prognostic-nutritional-index
#5
Hideo Matsumoto, Yuko Okamoto, Akimasa Kawai, Daisuke Ueno, Hisako Kubota, Haruaki Murakami, Masaharu Higashida, Toshihiro Hirai
PURPOSE: Preoperative nutritional status may impact surgical outcome and prognosis. We evaluated the predictive value of Onodera's prognostic nutritional index (O's-PNI) of surgical outcome following esophagectomy in esophageal cancer patients. PATIENTS AND METHODS: In total, 144 patients undergoing esophagectomy for esophageal cancer from April 2010 to May 2015 were evaluated, retrospectively. Eighty-four patients were enrolled in this study. O's-PNIs were calculated before surgery, discharge, and 1, 2, and 6 mo after discharge...
August 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28644887/sarcopenia-is-a-predictive-factor-for-intestinal-resection-in-admitted-patients-with-crohn-s-disease
#6
Shigeki Bamba, Masaya Sasaki, Azusa Takaoka, Kenichiro Takahashi, Hirotsugu Imaeda, Atsushi Nishida, Osamu Inatomi, Mitsushige Sugimoto, Akira Andoh
The relationship between skeletal muscle volume and the prognosis of patients with inflammatory bowel disease (IBD) remains undetermined. We conducted a retrospective study of 72 IBD patients who were admitted to the hospital due to disease exacerbation. We enrolled IBD patients who had undergone abdominal computed tomography and assessed the nutritional indices, such as the Onodera's prognostic nutritional index (O-PNI) and the controlling nutritional status (CONUT) index. The L3 skeletal muscle index (SMI), which is the ratio of the cross-sectional area of skeletal muscles at the level of the third lumbar (L3) vertebra to the height squared, was used to identify sarcopenia...
2017: PloS One
https://www.readbyqxmd.com/read/28534554/-relation-between-preoperative-prognostic-onodera-s-index-and-postsurgery-complications-in-the-r0-gastric-carcinoma-resection
#7
F Borda, C Miranda, A Borda, E Echeverría, A Guerra, J J Iñigo, J M Zozaya
BACKGROUND: It has been postulated in the Asian literature that a low prognostic nutritional index (OI) could be associated with a higher rate of complications following radical gastric cancer surgery, but there is a lack of data concerning western countries. The aim is to analyze the relationship between a low preoperative OI and the frequency and severity of surgical complications in R0 gastric cancer resection. PATIENTS AND METHODS: In the present article, 124 cases of gastric cancer with R0 resection were reviewed...
April 30, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/28442246/prognostic-impact-of-nutritional-risk-assessment-in-patients-with-chronic-schizophrenia
#8
Ming-Tsun Tsai, Tien-Hao Chang, Bo-Jian Wu
Protein-energy wasting is associated with poor outcome in various clinical settings. However, the prevalence of malnutrition and the prognostic impact of nutritional status are poorly understood in institutionalized patients with chronic schizophrenia. This study aimed to assess the predictive ability of the Geriatric Nutritional Risk Index and Onodera's Prognostic Nutritional Index for long-term outcomes in patients with chronic schizophrenia. All measurements, including nutritional scores, were performed at baseline after the enrollment of 542 (64...
April 22, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28301959/utility-of-clinico-biological-data-for-long-term-prognosis-of-head-and-neck-terminal-cancer
#9
Taiji Kawasaki, Koichiro Wasano, Sayuri Yamamoto, Shuta Tomisato, Kaoru Ogawa
OBJECTIVE: The prognosis of terminal head and neck cancer is traditionally determined using indices such as the palliative prognosis index. We aimed to develop an alternative prognosis index using clinico-biological data. METHODS: This retrospective case-series study included 33 head and neck cancer patients whose cancer recurred despite receiving radiation therapy between April 2010 and April 2014. Clinico-biological data were collected the day patients were diagnosed as terminal...
March 16, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28000452/phase-angle-and-onodera-s-prognostic-nutritional-index-in-critically-ill-patients
#10
Karina Marques Vermeulen, Leilane Lilian Araújo Leal, Mariana Câmara Martins Bezerra Furtado, Sancha Helena de Lima Vale, Lúcia Leite Lais
INTRODUCTION: Assessing severity and nutritional prognosis in critical patients has become increasingly important in recent years, since these parameters are related to morbidity/mortality and used to guide therapeutic options. OBJECTIVE: Determine nutritional prognosis through the Phase Angle (PA) and Onodera's Prognostic Nutritional Index (OPNI) and its relationship with severity, hospitalization time and mortality of critically ill patients. METHODS: Descriptive cross-sectional study, involving adult patients hospitalized in an Intensive Care Unit (ICU)...
November 29, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27896506/inflammation-based-prognostic-scores-utility-in-prognostication-and-patient-selection-for-cytoreduction-and-perioperative-intraperitoneal-chemotherapy-in-patients-with-peritoneal-metastasis-of-colonic-origin
#11
Chukwuemeka Ihemelandu
BACKGROUND: Tumor-associated systemic inflammatory response has been correlated with prognosis. Our aim was to analyze the utility of inflammation-based prognostic scores for prognostication and patient selection for cytoreduction and perioperative intraperitoneal chemotherapy (POIC) in patients diagnosed with peritoneal metastasis of colonic origin. METHODS: A retrospective analysis of a prospectively maintained database for all patients treated for peritoneal metastasis of colonic origin from February 2001 to April 2015...
November 28, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27847115/pre-therapeutic-nutritional-assessment-for-predicting-severe-adverse-events-in-patients-with-head-and-neck-cancer-treated-by-radiotherapy
#12
Takeyuki Kono, Koji Sakamoto, Seiichi Shinden, Kaoru Ogawa
BACKGROUND & AIMS: Malnutrition is common in patients with head and neck cancer (HNSCC). It may be related to severe adverse toxicity as a result of radiotherapy. The aim was to investigate nutritional screening factors for severe adverse events. METHODS: A retrospective chart review of 101 patients who underwent radiotherapy from 2009 to 2013 was performed. The relationships among severe adverse events and pretreatment nutritional parameters, including static variables (serum albumin, total protein, total lymphocyte counts, body mass index), dynamic variables (retinol-binding protein, transferrin, pre-albumin), and nutritional screening tools (Onodera's Prognostic Nutrition Index [O-PNI]; Nutrition Risk Index; Controlling Nutritional Status [CONUT] score; Nutritional Risk Screening 2002) were evaluated in addition to patient and treatment factors...
November 5, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27729804/prognostic-nutritional-index-predicts-prognosis-in-patients-with-metastatic-nasopharyngeal-carcinoma
#13
Gan-Bao Wei, Yao-Yong Lu, Rong-Wei Liao, Qing-Sheng Chen, Kun-Qiang Zhang
OBJECTIVE: This study aimed to investigate the prognostic value of Onodera's prognostic nutritional index (PNI) in patients with metastatic nasopharyngeal carcinoma (NPC). METHODS: A total of 187 patients with metastatic NPC treated with cisplatin-based chemotherapy were retrospectively reviewed. The PNI was calculated using the following formula: serum albumin level (gram per liter) +0.005× peripheral lymphocyte count (per cubic millimeter). A receiver operating characteristics curve for overall survival (OS) with the highest Youden index was determined to calculate the best cutoff value of PNI...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27446283/prognostic-factors-affecting-early-colectomy-in-patients-with-moderate-to-severe-ulcerative-colitis-treated-with-calcineurin-inhibitors
#14
Hiromitsu Ban, Shigeki Bamba, Atsushi Nishida, Osamu Inatomi, Makoto Shioya, Ken-Ichiro Takahashi, Hirotsugu Imaeda, Masaki Murata, Masaya Sasaki, Tomoyuki Tsujikawa, Akira Andoh
Calcineurin inhibitors (CNIs) such as cyclosporine A (CSA) and tacrolimus (FK506) are often used as a second-line drug for steroid-refractory or steroid-dependent patients with ulcerative colitis (UC). The aim of the present study was to determine the prognostic factors for early colectomy. A total of 85 hospitalized patients with UC (CSA, 50 patients; FK506, 35 patients) were enrolled. Colectomy carried out within 60 days of starting CNI therapy was defined as 'early colectomy'. To assess the prognostic factors affecting early colectomy, clinical practical variables, including the Onodera-prognostic nutritional index (O-PNI): 10xAlb+0...
August 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27431662/onodera-s-prognostic-nutritional-index-as-an-independent-prognostic-factor-in-clear-cell-renal-cell-carcinoma
#15
Matthew S Broggi, Dattatraya Patil, Yoram Baum, Peter T Nieh, Mehrdad Alemozaffar, John G Pattaras, Kenneth Ogan, Viraj A Master
OBJECTIVE: To evaluate the relationship between the Onodera Prognostic Nutritional Index (OPNI) and overall survival, as well as recurrence-free survival, in clear cell renal cell carcinoma (ccRCC) patients following nephrectomy. MATERIALS AND METHODS: Three hundred forty-one patients who underwent nephrectomy for ccRCC were analyzed. The optimum OPNI cutoff score of 44.7 was determined by receiver operating characteristic analysis and patients were placed in either the low or high OPNI group, with OPNI values of ≤44...
October 2016: Urology
https://www.readbyqxmd.com/read/27310954/nutritional-predictors-for-postoperative-short-term-and-long-term-outcomes-of-patients-with-gastric-cancer
#16
Mitsuro Kanda, Akira Mizuno, Chie Tanaka, Daisuke Kobayashi, Michitaka Fujiwara, Naoki Iwata, Masamichi Hayashi, Suguru Yamada, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Masahiko Koike, Hideki Takami, Yukiko Niwa, Kenta Murotani, Yasuhiro Kodera
Evidence indicates that impaired immunocompetence and nutritional status adversely affect short-term and long-term outcomes of patients with cancer. We aimed to evaluate the clinical significance of preoperative immunocompetence and nutritional status according to Onodera's prognostic nutrition index (PNI) among patients who underwent curative gastrectomy for gastric cancer (GC).This study included 260 patients with stage II/III GC who underwent R0 resection. The predictive values of preoperative nutritional status for postoperative outcome (morbidity and prognosis) were evaluated...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27215530/-onodera-prognostic-nutrition-index-predicts-nutrition-risk-in-gastrointestinal-elective-operation-patients
#17
Wen Luo, Yi Wang, Zhiyong Zhou, Hongying Li
OBJECTIVE: To evaluate the clinical effectiveness of Onodera prognostic nutrition index (OPNI) in the predictive value of nutrition risk. METHODS: In a prospective cohort study from July 2014 to June 2015 in the Department of General Surgery of the Ninth People's Hospital of Chongqing, NRS2002 and OPNI were conducted in 200 patients undergoing gastrointestinal elective operation. OPNI was calculated with serum albumin (Alb) and peripheral lymphocyte (TLC) [OPNI=Alb(10(9)/L)+5×TLC(10(9)/L)]...
May 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27207098/low-preoperative-prognostic-nutritional-index-predicts-poor-survival-post-gastrectomy-in-elderly-patients-with-gastric-cancer
#18
Katsunobu Sakurai, Tatsuro Tamura, Takahiro Toyokawa, Ryosuke Amano, Naoshi Kubo, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kiyoshi Maeda, Masaichi Ohira, Kosei Hirakawa
BACKGROUND: Preoperative nutritional status may predict short- and long-term outcomes of patients with cancer. OBJECTIVE: The aim of this study was to clarify the impact of preoperative nutritional status on outcomes of elderly patients who have undergone gastrectomy for gastric cancer (GC). METHODS: A review examining 147 patients treated for GC by gastrectomy at our institution between January 2004 and December 2011 was conducted. Onodera's prognostic nutritional index (PNI) was invoked, using an optimal cutpoint to stratify patients by high (PNI > 43...
October 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27067684/-outcome-and-problems-of-nab-paclitaxel-therapy-for-gastric-cancer-in-clinical-practice
#19
Toshifumi Doi, Takeshi Ishikawa, Tetsuya Okayama, Osamu Dohi, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiro Katada, Yoshio Sogame, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Hiroaki Yasuda, Junichi Sakagami, Hideyuki Konishi, Yuji Naito, Yoshito Itoh
Nanoparticle albumin-bound paclitaxel(nab-PTX)was approved for the treatment of gastric cancer without a large-scale clinical trial in Japan. Its safety and efficacy should be validated in clinical practice. We retrospectively investigated prognostic factors related to time to treatment failure(TTF)in 11 patients with unresectable or recurrent gastric cancer treated with nab- PTX in our hospital. In univariate analysis, Onodera's prognostic nutritional index(PNI)and the time from the start of first-line chemotherapy to the start of nab-PTX were related to TTF...
February 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27048552/colonic-stenting-as-a-bridge-to-surgery-for-obstructive-colorectal-cancer-advantages-and-disadvantages
#20
Naotsugu Haraguchi, Masataka Ikeda, Masakazu Miyake, Takuya Yamada, Yuko Sakakibara, Eiji Mita, Yuichiro Doki, Masaki Mori, Mitsugu Sekimoto
PURPOSE: To clarify the advantages and disadvantages of stenting as a bridge to surgery (BTS) by comparing the clinical features and outcomes of patients who underwent BTS with those of patients who underwent emergency surgery (ES). METHODS: We assessed technical success, clinical success, surgical procedures, stoma formation, complications, clinicopathological features, and Onodera's prognostic nutritional index (OPNI) in patients who underwent BTS and those who underwent ES...
November 2016: Surgery Today
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