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https://www.readbyqxmd.com/read/28633984/herbal-medicinal-products-in-pregnancy-which-data-are-available
#1
REVIEW
Jacqueline Wiesner, Werner Knöss
This review aims to highlight recent approaches concerning usage of (traditional) herbal medicinal products in pregnancy and to discuss appropriate strategies to handle limited information. Therefore, published monographs of the Committee on Herbal Medicinal products (HMPC) and selected publicly funded webpages, medicinal handbooks, publications and industry and health care organisations webpages were evaluated. While within the monographs of the HMPC a rather conservative approach could be found (mainly because of lacking nonclinical and/or clinical studies), all other sources display a wide variety of information or assessments, thereby often giving contradictory recommendations...
June 17, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28630768/plastic-surgery-inclusion-in-the-undergraduate-medical-curriculum-perception-challenges-and-career-choice-a-comparative-study
#2
M Farid, R Vaughan, S Thomas
OBJECTIVE: The undergraduate medical curriculum has been overcrowded with core learning outcomes with no formal exposure to plastic surgery. The aim of this study was to compare medical students from two educational settings for the basic understanding, preferred learning method, and factors influencing a career choice in plastic surgery. DESIGN AND SETTING: A prospective cohort study based on a web-based anonymous questionnaire sent to final year medical students at Birmingham University (United Kingdom), McGill University (Canada), and a control group (non-medical staff)...
2017: Plastic Surgery International
https://www.readbyqxmd.com/read/28622309/eyelid-and-fornix-reconstruction-in-abortive-cryptophthalmos-a-single-center-experience-over-12-years
#3
J Ding, Z Hou, Y Li, N Lu, D Li
PurposeAbortive cryptophthalmos is a rare congenital eyelid anomaly with poor prognosis for vision and cosmesis. The study aims to present its varied manifestations and surgical outcomes.Patients and methodsThe medical records of patients with abortive cryptophthalmos treated at the Oculoplastic Clinic of Beijing Tongren Hospital between January 2004 and May 2016 were reviewed. Early surgical intervention was performed when exposure keratopathy occurs. Upper eyelid and superior fornix were mainly reconstructed with sliding myocutaneous flap and scleral and amniotic grafts...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28619557/current-and-emerging-treatments-for-vitiligo
#4
REVIEW
Michelle Rodrigues, Khaled Ezzedine, Iltefat Hamzavi, Amit G Pandya, John E Harris
Clinicians should be aware that vitiligo is not merely a cosmetic disease and that there are safe and effective treatments available for vitiligo. It is important to recognize common and uncommon presentations and those with active disease, as well as their implications for clinical management; these were discussed in the first article in this continuing medical education series. Existing treatments include topical and systemic immunosuppressants, phototherapy, and surgical techniques, which together may serve to halt disease progression, stabilize depigmented lesions, and encourage repigmentation...
July 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28619537/synthesis-and-biological-evaluation-of-caffeic-acid-derivatives-as-potent-inhibitors-of-%C3%AE-msh-stimulated-melanogenesis
#5
Hyeju Jo, Minho Choi, Jaeuk Sim, Mayavan Viji, Siyuan Li, Young Hee Lee, Youngsoo Kim, Seung-Yong Seo, Yuanyuan Zhou, Kiho Lee, Wun-Jae Kim, Jin Tae Hong, Heesoon Lee, Jae-Kyung Jung
We have disclosed our effort to develop caffeic acid derivatives as potent and non-toxic inhibitors of α-MSH-stimulated melanogenesis to treat pigmentation disorders and skin medication including a cosmetic skin-whitening agent. The SAR studies revealed that cyclohexyl ester and secondary amide derivatives of caffeic acid showed significant inhibitory activities.
June 3, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28615153/-click-for-closer-care-a-content-analysis-of-community-pharmacy-websites-in-four-countries
#6
Sandra Zwier
BACKGROUND: Combinations of professional and commercial communication are typically very controversial, particularly in health care communication on the Internet. Websites of licensed community pharmacies on the other hand tend to raise remarkably little controversy, although they typically contain controversial combinations of clinical and commercial services previously unprecedented in professional health care communication. OBJECTIVE: The aim of this study was to fill the void of knowledge about the combination of clinical and commercial services presented on the websites of licensed community pharmacies...
June 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28609145/three-phase-partitioning-as-an-elegant-and-versatile-platform-applied-to-non-chromatographic-bioseparation-processes
#7
Jing-Kun Yan, Yao-Yao Wang, Wen-Yi Qiu, Haile Ma, Zhen-Bin Wang, Jian-Yong Wu
In recent years, a big trend has been the development of rapid, green, efficient, economical, and scalable approaches for the separation and purification of bioactive molecules from natural sources, which can be used in food, cosmetics, and medicine. As a new non-chromatographic bioseparation technology, three-phase partitioning (TPP) is attracting the attention of a growing number of scientists and engineers. Although a number of studies have been published in the last 40 years regarding the extraction, separation, and purification of numerous bioactive molecules using TPP systems, a background review on TPP partitioning fundamentals and its applications is much needed...
June 13, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28608750/aesthetics-in-thyroid-surgery-the-patient-perspective
#8
Katrina Chaung, William S Duke, Sun Jung Oh, Amanda Behr, Jennifer L Waller, Jeannie Daniel, David J Terris
Objectives To define characteristics that influence patient perceptions of thyroidectomy scar cosmesis. Study Design Prospective cohort study. Setting Tertiary endocrine surgery practice in an academic medical center. Subjects and Methods Institutional review board-approved trial in which 136 subjects were recruited from a population of patients being seen for either thyroid or sinus surgery and evaluated standardized photographs, superimposed with computer-generated thyroidectomy scars of varying lengths (2, 4, and 6 cm) and widths (1 and 2 mm), and graded their perception of the scars using the observer scar assessment scale (OSAS) domains of the patient and observer scar assessment scale...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28607825/cranioplasty-indications-procedures-and-outcome-an-institutional-experience
#9
Syed M Andrabi, Arif H Sarmast, Altaf R Kirmani, Abdul R Bhat
BACKGROUND: Cranioplasty, the repair of a skull vault defect by insertion of an object (bone or nonbiological materials such as metal or plastic plates), is a well-known procedure in modern neurosurgery. Brain protection and cosmetic aspects are the major indications of cranioplasty. A retroprospective study was conducted for evaluating the indications, materials used, complications, and outcome of cranioplasty. METHODS: This study was prospective from August 2013 to September 2015 and retrospective from August 2010 to July 2013...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28603463/case-report-two-cases-of-nicolau-syndrome-associated-with-glatiramer-acetate
#10
Dorlan J Kimbrough, Scott D Newsome
We report two cases of Nicolau syndrome (embolia cutis medicamentosa), a rare complication of injectable medications, both associated with the administration of 20 mg of subcutaneous glatiramer acetate. Both patients required surgical debridement and were subsequently treated conservatively without additional complications. Patient 1 opted to discontinue disease-modifying therapy. Patient 2 continued glatiramer acetate therapy without complications by using other injection sites. These cases highlight the need for prompt investigation of new unusual skin lesions in patients receiving injectable multiple sclerosis treatments (regardless of length of treatment and previous minor cosmetic concerns) and illustrate the clinical distinction between Nicolau syndrome and drug-induced skin necrosis...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28597284/comparison-of-single-incision-laparoscopic-percutaneous-extraperitoneal-closure-silpec-and-open-repair-for-pediatric-inguinal-hernia-a-single-center-retrospective-cohort-study-of-2028-cases
#11
Hizuru Amano, Yujiro Tanaka, Hiroshi Kawashima, Kyoichi Deie, Michimasa Fujiogi, Keisuke Suzuki, Kaori Morita, Tadashi Iwanaka, Hiroo Uchida
BACKGROUD: Recently, laparoscopic percutaneous extraperitoneal closure (LPEC) has gained increased popularity for pediatric inguinal hernia repair. To improve cosmesis, we developed single incision LPEC (SILPEC). The aim of this study was to assess the safety and feasibility of SILPEC compared with traditional open repair (OR). METHODS: This was a single-center retrospective cohort study of 2028 children who underwent inguinal hernia repair between April 2005 and August 2014...
June 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28594922/the-learning-curve-of-endoscopic-total-mastectomy-in-taiwan-a-multi-center-study
#12
Chin-Sheng Hung, Sheng-Wei Chang, Li-Min Liao, Cheng-Chiao Huang, Shih-Hsin Tu, Shou-Tung Chen, Dar-Ren Chen, Shou-Jen Kuo, Hung-Wen Lai, Ting-Mao Chou, Yao-Lung Kuo
INTRODUCTION: Laparoscopic techniques are commonly used in abdominal and gynecologic surgery, while breast cancer surgery has remained largely unchanged. In Asia, especially in Japan, many surgeons have started to use endoscopic surgery for breast cancer. In Taiwan, endoscopy-assisted breast surgery started in 2010. The benefits of this surgical method include smaller incisions, an axillary anatomic approach, clear vision, no oncologic compromise, and good cosmetic outcomes. This is the first report to discuss the learning curve of endoscopy-assisted breast surgery, including the difficulties experienced...
2017: PloS One
https://www.readbyqxmd.com/read/28575807/a-holistic-review-on-the-autoimmune-disease-vitiligo-with-emphasis-on-the-causal-factors
#13
REVIEW
Seema Patel, Abdur Rauf, Haroon Khan, Biswa Ranjan Meher, Syed Shams Ul Hassan
Vitiligo is an idiopathic systemic autoimmune disease affecting skin, hair and oral mucosa. This genetic yet acquired disease characterized by melanin loss is a cause of morbidity across all races. Though thyroid disturbance has been recognized as a key trigger of this pathology, an array of other factors plays critical role in its manifestation. Multiple hormones (corticotropin-releasing hormone, adrenocorticotropic hormone, α-melanocyte-stimulating hormone, melatonin, calcitriol, testosterone, estrogen), genes (Human leukocyte antigen (HLA), Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), Forkhead box D3 (FOXD3), Cluster of differentiation 117 (CD117), Estrogen receptor (ESR) 1, Cyclooxygenase-2 (COX2), Vitiligo-associated protein 1 (VIT1)), and lifestyle choices (stress, diet, cosmetic products, and medications) have been suspected as drivers of this disorder...
May 30, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28570907/melanin-gamma-rays-assistants-for-bismuth-oxide-nanoparticles-synthesis-at-room-temperature-for-enhancing-antimicrobial-and-photocatalytic-activity
#14
Ahmed I El-Batal, Gharieb S El-Sayyad, Abbas El-Ghamry, Kerolos M Agaypi, Mohamed A Elsayed, Mohamed Gobara
Melanin pigment has been deemed as a natural photoprotector with strong hydrophobicity. It allured considerable compatibility with many applications in medicine, food, and nanotechnology. Penicillium chrysogenium has been devoted to the green synthesis of melanin whereby optimizing its culture and environmental conditions. The impacts of alternative economic L-tyrosine natural sources (unprecedented alternate origins) and gamma radiation were pledged for the potential growing of the pigment. Herein, notable increases in melanin yield (6...
May 23, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28570472/a-recipe-for-improved-nonsurgical-cosmetic-outcomes-know-your-herbs-and-spices
#15
Hermine Warren
The nonsurgical cosmetic arena continues to grow, with more people consistently seeking minimally invasive procedures for facial rejuvenation. However, although these prospective patients are not seeking surgical correction to obtain their results, there is still the potential for nonsurgical procedures to yield adverse events posttreatment. Patients often do not realize that their dietary regimens may affect their nonsurgical cosmetic outcomes. For example, many patients desiring these types of treatments are often found to be taking prescription medications, herbs, and spices on a daily basis that may have the capacity to potentiate adverse outcomes such as bleeding and/or bruising...
April 2017: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/28566911/intense-pulsed-light-and-q-switched-1-064-nm-neodymium-doped-yttrium-aluminum-garnet-laser-treatment-for-the-scarring-lesion-of-discoid-lupus-erythematosus
#16
Yun Sun Byun, Jee Hee Son, Yong Se Cho, Bo Young Chung, Hee Jin Cho, Chun Wook Park, Hye One Kim
Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus that can cause permanent scarring. Treatment of DLE includes protection from sunlight and artificial sources of ultraviolet light, as well as systemic and topical medications. The first-line standard therapies are antimalarials and topical steroids. Other systemic therapies include systemic steroid, azathioprine, dapsone, and immunosuppressive agents. Topical tacrolimus and pimecrolimus have also been evaluated. Recent studies reported that several treatments, including pulsed dye laser, CO2 laser, intense pulsed light (IPL), and 1,064-nm long-pulse neodymium-doped yttrium aluminum (Nd:YAG) have been used for the cosmetic treatment of DLE...
June 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28561345/outcome-after-one-year-of-upper-airway-stimulation-for-obstructive-sleep-apnea-in-a-multicenter-german-post-market-study
#17
Armin Steffen, J Ulrich Sommer, Benedikt Hofauer, Joachim T Maurer, Katrin Hasselbacher, Clemens Heiser
OBJECTIVE/HYPOTHESIS: Upper airway stimulation (UAS) of the hypoglossal nerve has been implemented in the routine clinical practice for patients with moderate-to-severe obstructive sleep apnea (OSA) who could not adhere to continuous positive airway pressure. This study reports objective and patient-reported outcome after 12 months of implantation. STUDY DESIGN: Multicenter prospective single-arm study. METHODS: Consecutive patients who received the UAS system (Inspire Medical Systems, Inc...
May 31, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28554685/snail-mucus-glandular-origin-and-composition-in-helix-pomatia
#18
Sophie Greistorfer, Waltraud Klepal, Norbert Cyran, Andreas Gugumuck, Livia Rudoll, Johannes Suppan, Janek von Byern
Apart from their well-known culinary use, gastropod species such as Helix, which have a hydrogel-like mucus, are increasingly being exploited for cosmetic, bioengineering and medical applications. However, not only are the origin and composition of these "sticky" secretions far from being fully characterized, the number and morphology of the mucus glands involved is also uncertain. This study aims to characterize in detail the cutaneous glands of the Helix pomatia foot on morphological, histochemical and immunohistochemical levels...
May 5, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/28542816/identification-of-microorganisms-isolated-from-counterfeit-and-unapproved-decorative-contact-lenses
#19
Adrian D Land, Katie L Penno, Jennifer L Brzezinski
All contact lenses (corrective/noncorrective) are considered Class II or Class III medical devices under the Federal Food, Drug, and Cosmetic Act, which also states that contact lenses can only be obtained with a prescription. The Forensic Chemistry Center of the US Food & Drug Administration has examined over 300 decorative, noncorrective contact lenses obtained without a prescription. Our observations indicate that 60% of the counterfeit lenses and 27% of the unapproved lenses examined were positive for microbial contamination...
May 24, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28540795/radiofrequency-ablation-of-benign-thyroid-nodules-depicting-early-sign-of-regrowth-by-calculating-vital-volume
#20
Jung Suk Sim, Jung Hwan Baek, Joongyub Lee, Woojin Cho, Sung Il Jung
OBJECTIVE: We evaluated long-term follow-up results of radiofrequency ablation of benign thyroid nodules to analyse the role of marginal vital tissue on nodule regrowth. MATERIALS AND METHODS: We reviewed the medical records of 54 patients who underwent radiofrequency ablation between June 2008 and November 2013 with pressure symptoms, and/or cosmetic problems. All patients were followed up at least 12 months on three occasions. To evaluate an early sign of regrowth, three types of nodule volumes (total volume, ablated volume and vital volume) were measured and calculated using ultrasonography...
April 10, 2017: International Journal of Hyperthermia
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