Ruth Aguilar, Angeline Cruz, Alfons Jiménez, Alex Almuedo, Carme Roca Saumell, Marina Gigante Lopez, Oriol Gasch, Gemma Falcó, Ana Jiménez-Lozano, Angela Martínez-Perez, Consol Sanchez-Collado, Andrea Tedesco, Manuel Carlos López, María Jesús Pinazo, Thais Leonel, Zeno Bisoffi, Anna Färnert, Carlota Dobaño, Ana Requena-Méndez
BACKGROUND: We aimed to evaluate the performance of a novel multiplex serological assay, able to simultaneously detect IgG of six infections, as a screening tool for imported diseases in migrants. METHODS: Six panels of 40 (n = 240) anonymized serum samples with confirmed infections were used as positive controls to assess the multiplex assay's sensitivity. One panel of 40 sera from non-infected subjects was used to estimate the seropositivity cutoffs, and 32 non-infected sera were used as negative controls to estimate each serology's sensitivity and specificity...
December 21, 2023: Travel Medicine and Infectious Disease