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Prognostic Nutritional Index

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https://www.readbyqxmd.com/read/28321276/phase-angle-obtained-by-bioelectrical-impedance-analysis-independently-predicts-mortality-in-patients-with-cirrhosis
#1
Giliane Belarmino, Maria Cristina Gonzalez, Raquel S Torrinhas, Priscila Sala, Wellington Andraus, Luiz Augusto Carneiro D'Albuquerque, Rosa Maria R Pereira, Valéria F Caparbo, Graziela R Ravacci, Lucas Damiani, Steven B Heymsfield, Dan L Waitzberg
AIM: To evaluate the prognostic value of the phase angle (PA) obtained from bioelectrical impedance analysis (BIA) for mortality prediction in patients with cirrhosis. METHODS: In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker (PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models...
March 8, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28315180/inflammation-based-indexes-and-clinicopathologic-features-are-strong-predictive-values-of-preoperative-circulating-tumor-cell-detection-in-gastric-cancer-patients
#2
L Zheng, K Zou, C Yang, F Chen, T Guo, B Xiong
PURPOSE: Circulating tumor cell (CTC) count and the host inflammatory response are two independent predictors for patients with various malignant disease. Several inflammation-based indicators have been demonstrated to have prognostic value in many malignant solid tumors, including systemic immune-inflammation index (SII), neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and prognostic nutrition index (PNI). The aim of this study was to evaluate the predictive value of the inflammation-based indexes including SII, NLR PLR, and PNI for CTC detection of gastric cancer patients before surgery...
March 17, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28315008/the-optimal-cut-off-value-of-the-preoperative-prognostic-nutritional-index-for-the-survival-differs-according-to-the-tnm-stage-in-hepatocellular-carcinoma
#3
Yukiyasu Okamura, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhiko Uesaka
PURPOSE: To establish the optimal cut-off value of the preoperative prognostic nutritional index (PNI) for prognosis according to the Tumor Node Metastasis (TNM) stage of hepatocellular carcinoma (HCC) after curative resection. METHODS: This retrospective study reviewed the records of 375 patients. The optimal cut-off value of the PNI was established according to the TNM stage, and overall survival was compared between the low and high PNI groups. RESULTS: The optimal cut-off value of the PNI decreased with increasing TNM stage, with 52, 47, and 43 patients having stage I, II, and III HCC, respectively...
March 17, 2017: Surgery Today
https://www.readbyqxmd.com/read/28303380/nutritional-and-functional-factors-as-prognostic-of-surgical-cancer-patients
#4
Jéssica Härter, Silvana Paiva Orlandi, Maria Cristina Gonzalez
PURPOSE: We evaluated phase angle, sarcopenia, and handgrip strength as prognostic factors of postoperative morbimortality in patients with cancer. METHODOLOGY: We conducted a prospective study with 60 oncology patients admitted for elective surgery between November 2015 and May 2016. We calculated the standardized phase angle (SPA) and the skeletal mass index of the subjects based on their bioelectrical impedance tests. Handgrip strength (HGS) was measured using a hydraulic dynamometer...
March 16, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28301959/utility-of-clinico-biological-data-for-long-term-prognosis-of-head-and-neck-terminal-cancer
#5
Taiji Kawasaki, Koichiro Wasano, Sayuri Yamamoto, Shuta Tomisato, Kaoru Ogawa
OBJECTIVE: The prognosis of terminal head and neck cancer is traditionally determined using indices such as the palliative prognosis index. We aimed to develop an alternative prognosis index using clinico-biological data. METHODS: This retrospective case-series study included 33 head and neck cancer patients whose cancer recurred despite receiving radiation therapy between April 2010 and April 2014. Clinico-biological data were collected the day patients were diagnosed as terminal...
March 16, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28293741/influence-of-prognostic-nutritional-index-and-tumor-markers-on-survival-in-gastric-cancer-surgery-patients
#6
Hiroaki Saito, Yusuke Kono, Yuki Murakami, Hirohiko Kuroda, Tomoyuki Matsunaga, Yoji Fukumoto, Tomohiro Osaki
PURPOSE: Blood analytes are easily used in routine clinical practice. Tumor markers (TMs) are useful in diagnosing, treating, and predicting prognosis of gastric cancer (GC). The prognostic nutritional index (PNI) was also recently found to be useful in predicting GC prognosis. METHODS: The PNI and serum levels of CEA and CA19-9 of 453 patients with GC were measured to examine correlations between those levels and patients' prognoses. RESULTS: Of the 453 patients, 84 (18...
March 15, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28287320/preoperative-prognostic-nutritional-index-correlates-with-severe-complications-and-poor-survival-in-patients-with-colorectal-cancer-undergoing-curative-laparoscopic-surgery-a-retrospective-study-in-a-single-chinese-institution
#7
Xianglong Cao, Gang Zhao, Tao Yu, Qi An, Hua Yang, Gang Xiao
The prognostic nutritional index (PNI) has been correlated with long-term outcomes in cancer patients. However, the relationship between PNI, the postoperative complications, and long-term outcomes in patients with colorectal cancer (CRC) undergoing curative laparoscopic surgery has not been fully investigated. This retrospective study was conducted in the Beijing Hospital between January 2009 and January 2012. A total of 228 patients diagnosed with primary CRC undergoing curative laparoscopic surgery in the center were analyzed...
April 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28282392/predictive-value-of-initial-fdg-pet-features-for-treatment-response-and-survival-in-esophageal-cancer-patients-treated-with-chemo-radiation-therapy-using-a-random-forest-classifier
#8
Paul Desbordes, Su Ruan, Romain Modzelewski, Pascal Pineau, Sébastien Vauclin, Pierrick Gouel, Pierre Michel, Frédéric Di Fiore, Pierre Vera, Isabelle Gardin
PURPOSE: In oncology, texture features extracted from positron emission tomography with 18-fluorodeoxyglucose images (FDG-PET) are of increasing interest for predictive and prognostic studies, leading to several tens of features per tumor. To select the best features, the use of a random forest (RF) classifier was investigated. METHODS: Sixty-five patients with an esophageal cancer treated with a combined chemo-radiation therapy were retrospectively included. All patients underwent a pretreatment whole-body FDG-PET...
2017: PloS One
https://www.readbyqxmd.com/read/28251372/a-decrease-in-the-prognostic-nutritional-index-is-associated-with-a-worse-long-term-outcome-in-gastric-cancer-patients-undergoing-neoadjuvant-chemotherapy
#9
Kazuhiro Migita, Sohei Matsumoto, Kohei Wakatsuki, Masahiro Ito, Tomohiro Kunishige, Hiroshi Nakade, Mutsuko Kitano, Mitsuhiro Nakatani, Hiromichi Kanehiro
PURPOSE: The aim of this study was to evaluate the prognostic impact of the prognostic nutritional index (PNI) in gastric cancer patients undergoing neoadjuvant chemotherapy (NAC). METHODS: This study reviewed 54 patients with gastric cancer who underwent NAC and a subsequent R0 gastrectomy. The PNI before starting NAC and before gastrectomy were calculated using the following formula: 10 × serum albumin (g/dl) + 0.005 × total lymphocyte count (per mm(3))...
March 1, 2017: Surgery Today
https://www.readbyqxmd.com/read/28247035/the-value-of-the-prognostic-nutritional-index-pni-in-predicting-outcomes-and-guiding-the-treatment-strategy-of-nasopharyngeal-carcinoma-npc-patients-receiving-intensity-modulated-radiotherapy-imrt-with-or-without-chemotherapy
#10
Jingjing Miao, Weiwei Xiao, Lin Wang, Fei Han, Haijun Wu, Xiaowu Deng, Xiang Guo, Chong Zhao
PURPOSE: The purpose of this study was to investigate the significance of the Prognostic Nutritional Index (PNI) in predicting prognoses and guiding treatment choices of nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy (IMRT). METHODS: The 539 patients with newly diagnosed non-metastatic NPC were retrospectively analysed. The PNI was calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm(3))...
February 28, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28243747/impact-of-the-prognostic-nutritional-index-on-the-recovery-and-long-term-oncologic-outcome-of-patients-with-colorectal-cancer
#11
Gyoung Tae Noh, Jeonghee Han, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim
PURPOSE: The prognostic nutritional index (PNI) has been reported to be a predictive marker for surgical outcomes and prognosis in gastrointestinal malignancies. In this study, we aimed to identify the impact of preoperative PNI on the recovery and long-term oncologic outcome of patients with colorectal cancer (CRC). METHODS: A total of 3569 patients who underwent curative resection for CRC were enrolled, and their medical records were analyzed retrospectively. Preoperative PNI was calculated as 10× serum albumin concentration (g/dL) + 0...
February 27, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28223828/preoperative-albumin-to-globulin-ratio-and-prognostic-nutrition-index-predict-prognosis-for-glioblastoma
#12
Wen-Zhe Xu, Feng Li, Zhen-Kuan Xu, Xuan Chen, Bin Sun, Jing-Wei Cao, Yu-Guang Liu
OBJECTIVE: Impaired immunonutritional status has disadvantageous effects on outcomes for cancer patients. Preoperative albumin-to-globulin ratio (AGR) and the prognostic nutrition index (PNI) have been used as prognostic factors in various cancers. We aimed to evaluate the clinical significance of the AGR and PNI in glioblastoma. MATERIALS AND METHODS: This retrospective analysis involved 166 patients. Demographic, clinical, and laboratory data were collected. AGR and the PNI were calculated as AGR = albumin/(total serum protein - albumin) and PNI = albumin (g/L) + 5 × total lymphocyte count (10(9)/L)...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28219213/-clinical-application-value-of-prognostic-nutritional-index-for-predicting-survival-in-patients-with-advanced-non-small-cell-lung-cancer
#13
W J Xu, Y M Kang, L Zhou, F F Chen, Y H Song, C Q Zhang
Objective: To explore the clinical application value of prognostic nutritional index(PNI) for predicting overall survival(OS) in patients with advanced non-small cell lung cancer (NSCLC). Methods: 123 patients with histologically confirmed non-small cell lung cancer were enrolled in this study, and their clinical and laboratory data were reviewed. The PNI was calculated as 10×serum albumin value+ 5×total lymphocyte countin peripheral blood.Univariate and multivariate analyses were used to identify the potential prognostic factors for advanced NSCLC...
February 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28213742/comparison-of-systemic-inflammatory-and-nutritional-scores-in-colorectal-cancer-patients-who-underwent-potentially-curative-resection
#14
Ryuma Tokunaga, Yasuo Sakamoto, Shigeki Nakagawa, Daisuke Izumi, Keisuke Kosumi, Katsunobu Taki, Takaaki Higashi, Tatsunori Miyata, Yuji Miyamoto, Naoya Yoshida, Hideo Baba
BACKGROUND: Various systemic inflammatory and nutritional scores have been reported to predict postoperative outcomes. This study aimed to investigate the best systemic inflammatory and nutritional scores in colorectal cancer (CRC) patients who underwent potentially curative resection. METHOD: We evaluated 468 consecutive CRC patients in this study. Comparisons of systemic inflammatory and nutritional scores, including the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), prognostic index (PI), prognostic nutritional index (PNI), and modified Glasgow prognostic score (mGPS), were performed using univariate/multivariate analyses for patient survival...
February 17, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28209304/prognostic-value-of-the-nutritional-risk-index-in-heart-transplant-recipients
#15
Eduardo Barge-Caballero, Fernando García-López, Raquel Marzoa-Rivas, Gonzalo Barge-Caballero, David Couto-Mallón, María J Paniagua-Martín, Miguel Solla-Buceta, Carlos Velasco-Sierra, Francisco Pita-Gutiérrez, José M Herrera-Noreña, José J Cuenca-Castillo, José Manuel Vázquez-Rodríguez, María G Crespo-Leiro
INTRODUCTION AND OBJECTIVES: To study the prognostic impact of preoperative nutritional status, as assessed through the nutritional risk index (NRI), on postoperative outcomes after heart transplantation (HT). METHODS: We conducted a retrospective, single-center study of 574 patients who underwent HT from 1991 to 2014. Preoperative NRI was calculated as 1.519 × serum albumin (g/L) + 41.7 × (body weight [kg] / ideal body weight [kg]). The association between preoperative NRI and postoperative outcomes was analyzed by means of multivariable logistic regression and multivariable Cox regression...
February 10, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28208962/the-effect-of-nutritional-status-on-outcome-of-hospitalization-in-paediatric-liver-disease-patients
#16
Yasmeen Mansi, Shereen Abdel Ghaffar, Shaymaa Sayed, Hanaa El-Karaksy
INTRODUCTION: Liver is an important organ for metabolism. It has a major role in integrating the various biochemical pathways of metabolism. Thus, children with chronic liver disease are at high risk for developing undernutrition, with important prognostic implications. AIM: To evaluate the nutritional status of hospitalized paediatric liver disease patients and its effect on outcome. MATERIALS AND METHODS: We prospectively analysed the nutritional status of 59 consecutive patients during their first 24 hours of admission, at the Hepatology Unit, using the following indices: weight/age, height/age, weight/height, Body Mass Index (BMI), arm circumference and triceps skinfold, subcapular skinfold, and mid upper arm circumference...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28204965/prognostic-value-of-simple-frailty-and-malnutrition-screening-tools-in-patients-with-acute-heart-failure-due-to-left-ventricular-systolic-dysfunction
#17
S Sze, J Zhang, P Pellicori, D Morgan, A Hoye, A L Clark
BACKGROUND: Frailty and malnutrition are common in patients with heart failure (HF), and are associated with adverse outcomes. We studied the prognostic value of three malnutrition and three frailty indices in patients admitted acutely to hospital with HF. METHODS: 265 consecutive patients [62% males, median age 80 (interquartile range (IQR): 72-86) years, median NTproBNP 3633 (IQR: 2025-6407) ng/l] admitted with HF between 2013 and 2014 were enrolled. Patients were screened for frailty using the Derby frailty index (DFI), acute frailty network (AFN) frailty criteria, and clinical frailty scale (CFS) and for malnutrition using the geriatric nutritional risk index (GNRI), controlling nutritional status (CONUT) score and prognostic nutritional index (PNI)...
February 15, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28185108/low-prognostic-nutritional-index-associated-with-cardiovascular-disease-mortality-in-incident-peritoneal-dialysis-patients
#18
Fenfen Peng, Wenjing Chen, Weidong Zhou, Peilin Li, Hongxin Niu, Yihua Chen, Yan Zhu, Haibo Long
PURPOSE: The prognostic nutritional index (PNI), a variable based on serum albumin concentration and total lymphocyte count in peripheral blood, is reported as a predictor of mortality in a variety of malignant tumor population. This study is aimed to evaluate whether PNI has prognostic value in patients on peritoneal dialysis (PD). METHODS: This was a single-center, retrospective observational cohort study conducted in incident PD patients from January 1, 2006 to June 30, 2014, and followed until June 30, 2015...
February 10, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28174485/prognostic-nutritional-index-is-an-independent-prognostic-factor-for-gastric-cancer-patients-with-peritoneal-dissemination
#19
Runcong Nie, Shuqiang Yuan, Shi Chen, Xiaojiang Chen, Yongming Chen, Baoyan Zhu, Haibo Qiu, Zhiwei Zhou, Junsheng Peng, Yingbo Chen
OBJECTIVE: The predictive and prognostic role of prognostic nutritional index (PNI) in gastric cancer patients with peritoneal dissemination remains unclear. This study aims to explore the role of the PNI in predicting outcomes of gastric cancer patients with peritoneal dissemination. METHODS: A total of 660 patients diagnosed with gastric adenocarcinoma with peritoneal metastasis between January 2000 and April 2014 at Sun Yat-sen University Cancer Center and the Sixth Affiliated Hospital of Sun Yat-sen University were retrospectively analyzed...
December 2016: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/28144052/evaluation-of-plasma-leptin-tumor-necrosis-factor-%C3%AE-and-prealbumin-as-prognostic-biomarkers-during-clinical-recovery-from-acute-exacerbations-of-chronic-obstructive-pulmonary-disease
#20
Anant Mohan, Sneh Arora, Arvind Uniyal, Rosemary Poulose, Kalpana Luthra, R M Pandey, Randeep Guleria
BACKGROUND: Inflammatory and nutritional biomarkers have an important bearing on outcomes of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), but the temporal profile of these compounds during an acute episode is unclear. PATIENTS AND METHODS: Plasma leptin, prealbumin, and tumor necrosis factor-alpha (TNF-α) were estimated at baseline and before hospital discharge in patients with AECOPD. RESULTS: A total of 82 patients were evaluated (66 males; mean (standard deviation) age, 61...
January 2017: Lung India: Official Organ of Indian Chest Society
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