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Prognostic Nutritional Index

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https://www.readbyqxmd.com/read/29344381/impact-of-nutritional-indices-on-mortality-in-patients-with-heart-failure
#1
Akiomi Yoshihisa, Yuki Kanno, Shunsuke Watanabe, Tetsuro Yokokawa, Satoshi Abe, Makiko Miyata, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Takafumi Ishida, Yasuchika Takeishi
Background: Malnutrition is a common condition that is associated with adverse prognosis in patients with heart failure (HF). The Prognostic Nutritional Index (PNI), Geriatric Nutritional Risk Index (GNRI) and controlling nutritional status (CONUT) have all been used as objective indices for evaluating nutritional status. We aimed to clarify the relationship between these nutritional indices and the parameters of inflammatory markers, cardiac function and exercise capacity, as well as to compare the ability of these indexes for predicting mortality...
2018: Open Heart
https://www.readbyqxmd.com/read/29341506/impact-of-preoperative-anemia-on-outcomes-in-patients-undergoing-curative-resection-for-gastric-cancer-a-single-institution-retrospective-analysis-of-2163-chinese-patients
#2
Xuechao Liu, Haibo Qiu, Yuying Huang, Dazhi Xu, Wei Li, Yuanfang Li, Yingbo Chen, Zhiwei Zhou, Xiaowei Sun
We sought to evaluate whether preoperative anemia was an important determinant of survival in gastric cancer (GC). A single institution cohort of 2163 GC patients who underwent curative resection were retrospectively analyzed. Anemia was defined as a preoperative hemoglobin level <120 g/L in males and <110 g/L in females. Overall survival (OS) was analyzed using the Kaplan-Meier method, and a multivariate Cox proportional hazards model was performed to identify the independent prognostic factor. Anemic patients had a poorer OS compared with nonanemic patients after resection for tumor-nodes-metastasis (TNM) stage III tumors (5-year OS rate: 32...
January 17, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29325800/platelet-to-lymphocyte-ratio-is-a-predictive-marker-of-prognosis-and-therapeutic-effect-of-postoperative-chemotherapy-in-non-metastatic-esophageal-squamous-cell-carcinoma
#3
Yuchong Yang, Hao Xu, Likun Zhou, Ting Deng, Tao Ning, Rui Liu, Le Zhang, Xia Wang, Shaohua Ge, Hongli Li, Yi Ba
Increasing evidence indicated that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and prognostic nutritional index (PNI), can be used as prognostic indicators in esophageal squamous cell carcinoma (ESCC). However, which is the best predictor for prognosis in ESCC remain controversial. Few studies focused on the association between inflammatory biomarkers and postoperative chemotherapy. A cohort of 515 non-metastatic ESCC patients was reviewed retrospectively...
January 8, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29318218/potential-benefit-associated-with-delaying-initiation-of-hemodialysis-in-a-japanese-cohort
#4
Satoshi Higuchi, Izaya Nakaya, Kazuhiro Yoshikawa, Yoichiro Chikamatsu, Ken-Ei Sada, Suguru Yamamoto, Satoko Takahashi, Hiroyo Sasaki, Jun Soma
Introduction: Late referral to a nephrologist, the type of vascular access, nutritional status, and the estimated glomerular filtration rate (eGFR) at the start of hemodialysis (HD) have been reported as independent risk factors of survival for patients who begin HD. The aim of this study was to clarify the influence of the HD-free interval from the time of an eGFR of 10 ml/min per 1.73 m2 (IGFR10-HD) on patient outcome. Methods: We enrolled 124 patients aged older than 20 years who had HD initiated in a general hospital...
July 2017: KI Reports
https://www.readbyqxmd.com/read/29302378/potential-utility-of-fdg-pet-ct-as-a-non-invasive-tool-for-monitoring-local-immune-responses
#5
Seungho Lee, Seohee Choi, Sang Yong Kim, Mi Jin Yun, Hyoung-Il Kim
Purpose: The tumor microenvironment is known to be associated with the metabolic activity of cancer cells and local immune reactions. We hypothesized that glucose metabolism measured by 2-deoxy-2-(18F)fluoro-D-glucose (18F-FDG) positron emission tomography (PET)-computed tomography (CT) (18F-FDG PET-CT) would be associated with local immune responses evaluated according to the presence of tumor infiltrating lymphocytes (TILs). Materials and Methods: We retrospectively reviewed 56 patients who underwent 18F-FDG PET-CT prior to gastrectomy...
December 2017: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/29290069/preoperative-prognostic-nutritional-index-predicts-long-term-surgical-outcomes-in-patients-with-esophageal-squamous-cell-carcinoma
#6
Noriyuki Hirahara, Yoshitsugu Tajima, Yusuke Fujii, Shunsuke Kaji, Tetsu Yamamoto, Ryoji Hyakudomi, Takahito Taniura, Yoshiko Miyazaki, Takashi Kishi, Yasunari Kawabata
BACKGROUND: The purpose of the present study is to investigate the utility of prognostic nutritional index (PNI) as a simple and readily available marker in esophageal squamous cell carcinoma (ESCC). METHODS: We retrospectively analyzed 169 patients who underwent potentially curative esophagectomy, for histologically verified ESCC. We decided to set the optimal cutoff value for preoperative PNI levels at 49.2, based on the cancer-specific survival (CSS) and the overall survival (OS) by receiver operating characteristic curve analysis...
December 31, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29289386/mortality-risk-factors-in-elderly-patients-in-intensive-care-without-limitation-of-therapeutic-effort
#7
S E Giannasi, M S Venuti, A D Midley, N Roux, C Kecskes, E San Román
OUTCOME: To determine mortality prognostic factors in elderly patients who are admitted to intensive care units (ICUs) due to acute critical illness. DESIGN: A prospective cohort study was carried out. SETTING: A polyvalent Intensive Care Unit at a University Hospital in Argentina. PATIENTS OR PARTICIPANTS: We included 249 patients over 65years of age who were consecutively admitted to the ICU and required mechanical ventilation for more than 48hours, between January 2011 and December 2012...
December 27, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/29285616/correlation-between-the-skeletal-muscle-index-and-surgical-outcomes-of-pancreaticoduodenectomy
#8
Kenta Sui, Takehiro Okabayshi, Jun Iwata, Sojiro Morita, Tatsuaki Sumiyoshi, Tatsuo Iiyama, Yasuhiro Shimada
PURPOSES: Sarcopenia is known to be associated with a worse prognosis following abdominal operations; however, the relationship between sarcopenia and the outcomes of pancreaticoduodenectomy remains unclear. MATERIALS: We measured body composition parameters, including total abdominal muscle area, using preoperative staging computed tomography (CT), in patients undergoing pancreaticoduodenectomy for periampullary cancer. The incidence of sarcopenia among these patients was evaluated and multivariable analysis was performed to identify independent predictors of postoperative pancreatic fistula...
December 28, 2017: Surgery Today
https://www.readbyqxmd.com/read/29285377/elevated-neutrophil-to-lymphocyte-ratio-is-associated-with-nutritional-impairment-immune-suppression-resistance-to-s-1-plus-cisplatin-and-poor-prognosis-in-patients-with-stage-iv-gastric-cancer
#9
Kenji Gonda, Masahiko Shibata, Yu Sato, Maria Washio, Hiroyuki Takeshita, Hirofumi Shigeta, Michikazu Ogura, Shinichi Oka, Shinich Sakuramoto
Gastric cancer continues to be a major cause of morbidity and mortality worldwide. Recently, there has been a growing interest in the host inflammatory response and there is increasing evidence that the neutrophil to lymphocyte ratio (NLR), which is a useful marker of systemic inflammation, can be an effective prognostic indicator in various types of malignant diseases. A total of 110 patients with stage IV gastric cancer who received chemotherapy of S-1 plus cisplatin were enrolled in this study. Eleven patients did not complete four cycles of the chemotherapy...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29241167/nutritional-screening-and-clinical-outcome-in-hospitalized-patients-with-crohn-s-disease
#10
Azusa Takaoka, Masaya Sasaki, Naoko Nakanishi, Mika Kurihara, Akiko Ohi, Shigeki Bamba, Akira Andoh
BACKGROUND/AIMS: Hospitalized patients with Crohn's disease (CD) can develop severe nutritional deficits. However, the nutritional screening tools with the most utility for such patients are still unknown. METHODS: Nutritional status of 40 CD patients was assessed on admission using several screening tools and laboratory tests. Their validity was evaluated in relation to length of hospital stay (LOS) and intestinal resection. Receiver operating characteristic analysis was performed to predict prolonged LOS (≥28 days)...
December 14, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29238571/immunonutrition-within-enhanced-recovery-after-surgery-eras-an-unresolved-matter
#11
EDITORIAL
Ruchir Gupta, Anthony Senagore
Preoperative malnutrition because of poor oral intake significantly increases the risk of adverse events after surgery and leads to increased length of stay. While immunonutrition has been utilized in the non-ERAS setting, its utility in both minimally invasive surgery and ERAS pathway procedures remain poorly defined. There are at least ten meta-analyses regarding the assessment of immunonutrition, but virtually, all of these were performed in an era prior to minimally invasive surgery, adoption of enhanced recovery protocols, and an understanding of the assessment and physiology of sarcopenia...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/29216950/-effect-of-early-enteral-nutrition-standardized-treatment-on-blood-glucose-and-prognosis-in-acute-respiratory-distress-syndrome-patients-with-mechanical-ventilation
#12
Chunmiao Zhong, Chaohui Ji, Zhuquan Dai, Kai Fu, Xiaohong Wen, Huibin Pan
OBJECTIVE: To study the effect of early entreat nutrition (EN) standardized treatment on optimization of blood glucose control and prognosis in acute respiratory distress syndrome (ARDS) patients with mechanical ventilation (MV). METHODS: Forty-two patients with MV of ARDS admitted to Huzhou First Municipal People's Hospital from April 2015 to March 2017 were enrolled. April 1st, 2016 was taken as the time node, the patients treated from April 1st, 2015 to March 31st, 2016 were assigned in the control group (n = 20), while the patients treated from April 1st, 2016 to March 31st, 2017 were included in the experimental group (n = 22)...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29212959/geriatric-nutritional-risk-index-predicts-cardiovascular-events-in-patients-at-risk-for-heart-failure
#13
Masatoshi Minamisawa, Takashi Miura, Hirohiko Motoki, Yasushi Ueki, Hitoshi Nishimura, Kunihiko Shimizu, Wataru Shoin, Mikiko Harada, Tomoaki Mochidome, Keisuke Senda, Koji Yoshie, Yasutaka Oguchi, Naoto Hashizume, Naoyuki Abe, Tatsuya Saigusa, Soichiro Ebisawa, Atsushi Izawa, Jun Koyama, Uichi Ikeda, Koichiro Kuwahara
BACKGROUND: The geriatric nutritional risk index (GNRI) is a simple and objective nutritional assessment tool for elderly patients. Lower GNRI values are associated with a worse prognosis in patients with heart failure (HF). However, few data are available regarding the prognostic effect of the GNRI value for risk stratification in patients at risk for HF.Methods and Results:We retrospectively investigated 1,823 consecutive patients at risk for HF (Stage A/B) enrolled in the IMPACT-ABI Study...
December 6, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29208341/hemodynamic-correlates-of-nutritional-indexes-in-heart-failure
#14
Yu Horiuchi, Shuzou Tanimoto, Taishi Okuno, Jiro Aoki, Kazuyuki Yahagi, Yu Sato, Tetsu Tanaka, Keita Koseki, Kota Komiyama, Hiroyoshi Nakajima, Kazuhiro Hara, Kengo Tanabe
BACKGROUND: Malnutrition in heart failure (HF) is related to altered intestinal function, which could be due to hemodynamic changes. We investigated the usefulness of novel nutritional indexes in relation to hemodynamic parameters. METHODS: We retrospectively analyzed 139 HF patients with reduced ejection fraction who underwent right heart catheterization. We investigated correlations between right side pressures and nutritional indexes, which include controlling nutritional (CONUT) score and geriatric nutritional risk index (GNRI)...
December 2, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29200869/preoperative-prognostic-nutritional-index-and-nomogram-predicting-recurrence-free-survival-in-patients-with-primary-non-muscle-invasive-bladder-cancer-without-carcinoma-in-situ
#15
Jianfeng Cui, Shouzhen Chen, Qiyu Bo, Shiyu Wang, Ning Zhang, Meng Yu, Wenfu Wang, Jie Han, Yaofeng Zhu, Benkang Shi
Background and objectives: Among the cancers of the urogenital system, bladder cancer is ranked second both in incidence and mortality, and hence, a more accurate estimate of the prognosis for individual patients with non-muscle-invasive bladder cancer (NMIBC) is urgently needed. Prognostic nutritional index (PNI) which is based on serum albumin levels and peripheral lymphocyte count has been confirmed to have prognostic value in various cancers. The aim of this study was to clarify the prognostic value of PNI in patients with NMIBC...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29193777/pretreatment-c-reactive-protein-albumin-ratio-is-associated-with-poor-survival-in-patients-with-stage-ib-iia-cervical-cancer
#16
Weiwei Zhang, Kejun Liu, Bin Ye, Weijiang Liang, Yazhou Ren
Previous studies have shown that the C-reactive protein/albumin ratio (CAR) is a prognostic indicator in multiple types of carcinomas. This study is the first to evaluate the prognostic significance of CAR in stage IB-IIA cervical cancer patients treated with radical surgery, as well as that of several other inflammation-based factors, including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and prognostic nutritional index (PNI). A total of 235 patients were enrolled in this study...
November 28, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29188899/utility-of-three-prognostic-risk-scores-in-predicting-outcomes-in-elderly-non-malignant-patients-after-percutaneous-gastrostomy
#17
Ç Kalkan, A Ç Kartal, F Karakaya, A Tüzün, I Soykan
BACKGROUND/OBJECTIVES: Percutaneous endoscopic gastrostomy is a method of providing enteral feeding to patients who cannot take adequate oral nutrition. The aims of this study were to determine the performance of malnutrition and mortality scoring systems for predicting short and long-term mortality in elderly patients who had undergone gastrostomy procedure due to non-malignant conditions. DESIGN: Retrospective cohort study. SETTING: University hospital in Turkey...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29187874/albumin-and-fibrinogen-combined-prognostic-grade-predicts-prognosis-of-patients-with-prostate-cancer
#18
Yanqing Wang, Wei Chen, Chuanyi Hu, Xiaofei Wen, Jiahua Pan, Fan Xu, Yinjie Zhu, Xiaoguang Shao, Xun Shangguan, Liancheng Fan, Jianjun Sha, Zezhou Wang, Yong Cai, Qiang Liu, Baijun Dong, Wei Xue
Background: The nutritional status and systemic inflammation are thought to be associated with outcome in multiple types of cancer. The objective of this study was to determine the prognostic value of pretreatment albumin and fibrinogen combined prognostic grade (AFPG) in prostate cancer (PCa). Methods: 462 prostate cancer patients who had undergone androgen deprivation therapy (ADT) as first-line therapy at four cencters were retrospectively analyzed. The serum albumin levels and plasma fibrinogen levels were measured at the time of diagnosis...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/29187486/relationship-between-preoperative-sarcopenia-status-and-immuno-nutritional-parameters-in-patients-with-early-stage-non-small-cell-lung-cancer
#19
Fumihiro Shoji, Taichi Matsubara, Yuka Kozuma, Naoki Haratake, Takaki Akamine, Shinkichi Takamori, Masakazu Katsura, Gouji Toyokawa, Tatsuro Okamoto, Yoshihiko Maehara
BACKGROUND: Although the skeletal muscle in the region of the third lumbar vertebra (L3) is generally assessed in order to judge sarcopenia, not every patient with non-small cell lung cancer (NSCLC) undergoes computed tomography including the L3 region. We hypothesized that immuno-nutritional parameters could predict the existence of sarcopenia in patients with NSCLC. AIM: The aim of this study was to retrospectively investigate the correlation between preoperative sarcopenia and immuno-nutritional parameters in patients with early-stage NSCLC...
December 2017: Anticancer Research
https://www.readbyqxmd.com/read/29182777/evaluation-of-a-prognostic-scoring-system-based-on-the-systemic-inflammatory-and-nutritional-status-of-patients-with-locally-advanced-non-small-cell-lung-cancer-treated-with-chemoradiotherapy
#20
Takamasa Mitsuyoshi, Yukinori Matsuo, Hitoshi Itou, Takashi Shintani, Yusuke Iizuka, Young Hak Kim, Takashi Mizowaki
Systemic inflammation and poor nutritional status have a negative effect on the outcomes of cancer. Here, we analyzed the effects of the pretreatment inflammatory and nutritional status on clinical outcomes of locally advanced non-small-cell lung cancer (NSCLC) patients treated with chemoradiotherapy. We retrospectively reviewed 89 patients with locally advanced NSCLC treated with chemoradiotherapy between July 2006 and June 2013. Serum C-reactive protein (CRP) was assessed as an inflammatory marker, and serum albumin, body mass index (BMI) and skeletal mass index were assessed as nutritional status markers...
November 22, 2017: Journal of Radiation Research
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