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Spine degenerative disease

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https://www.readbyqxmd.com/read/28535941/-anesthetic-management-of-two-patients-with-alkaptonuric-ochronosis-for-total-knee-arthroplasty
#1
Betul Kozanhan
The current case report describes two cases of alkaptonuric ochronosis for anesthetic management. Alkaptonuria is a rare genetic orphan disease of tyrosine metabolism characterized by an accumulation of homogentisic acid in cartilage and connective tissues. Patients present most commonly for orthopedic joint surgery due to progressive arthropathy that can be misdiagnosed many a times. However respiratory, airway, cardiovascular and genitourinary systems complications can occur with age progressing. Restricted range of motion of cervical spine may lead to difficulty with airway management...
May 20, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28533943/etiology-and-treatment-of-amyotrophic-lateral-sclerosis
#2
Hernando Rafael, Juan Oscar David, Antonio Santiago Vilca
BACKGROUND: To date all researchers conclude that the etiology of Amyotrophic lateral sclerosis (ALS) is not known. On the contrary, since August 2009, we believe that disease is of ischemic origin in the anterior surface of the medulla oblongata. MATERIAL AND METHOD: We present our surgical experience into 45 patients with ALS (bulbar form in 36 cases and spinal form in 9). Preoperative MRI scans revealed microinfarcts in the medulla oblongata and/or cervical cord...
2017: American Journal of Neurodegenerative Disease
https://www.readbyqxmd.com/read/28532909/volume-outcome-relationship-after-1-and-2-level-anterior-cervical-discectomy-and-fusion
#3
Rafael De la Garza Ramos, Jonathan Nakhla, Rani Nasser, Ajit Jada, Niketh Bhashyam, Merritt D Kinon, Reza Yassari
OBJECTIVE: To investigate the impact of surgeon volume on inpatient morbidity after 1- and 2-level anterior cervical discectomy and fusion (ACDF). METHODS: Data from the Nationwide Inpatient Sample from 2009 were extracted. All adult patients who underwent an elective 1- or 2-level ACDF for degenerative cervical spine disease were identified. Surgeon volume was analyzed as a continuous and categorical variable (very-low (<12 procedures per year), low (12 - 23), medium (24 - 35), high (36 - 47), and very-high volume (48 or more))...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28525493/influence-of-myelography-and-postmyelographic-ct-on-therapeutic-decisions-in-degenerative-diseases-of-the-cervical-spine
#4
Thomas Westermaier, Christina Doerr, Christian Stetter, Thomas Linsenmann, Stefan Koehler, Joerg Eriskat, Laszlo Solymosi, Ralf-Ingo Ernestus
STUDY DESIGN: A retrospective analysis of clinical records and radiologic imaging by 3 independent reviewers to assess the indication for surgical treatment with and without myelography and postmyelographic computed tomography (MCT). OBJECTIVE: To evaluate whether myelography and MCT obtained in addition to magnetic resonance imaging (MRI) influence therapeutic decisions in degenerative diseases of the cervical spine. SUMMARY OF BACKGROUND DATA: MRI has become the standard examination in spinal diseases...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525473/is-total-disk-replacement-a-cost-effective-treatment-for-cervical-degenerative-disk-disease
#5
Bernd Wiedenhöfer, Joachim Nacke, Mike Stephan, Wiltrud Richter, Claus Carstens, Markus Eichler
STUDY DESIGN: A retrospective study. OBJECTIVE: The objective of this study was to assess the cost-effectiveness and clinical outcome of motion-preserving versus fusion procedures in cervical spine surgery. SUMMARY OF BACKGROUND DATA: During the last decade there has been a huge growth in spine surgery with a concurrent increase in the economic burden. Currently, there appear to be no differences in clinical outcome between cervical total disk replacement (TDR) and spinal fusion (SF)...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525471/cervical-disk-replacement-with-discover-versus-fusion-in-a-single-level-cervical-disk-disease-a-prospective-single-center-randomized-trial-with-a-minimum-2-year-follow-up
#6
Marjan Rožanković, Sergej M Marasanov, Miroslav Vukić
STUDY DESIGN: Prospective randomized study. OBJECTIVE: To compare the clinical outcome after Discover arthroplasty versus anterior cervical discectomy and fusion (ACDF) in patients treated for symptomatic single-level cervical disk disease. SUMMARY OF BACKGROUND DATA: ACDF is still the gold standard for surgical treatment of cervical spine degenerative disk disease. However, results of many studies suggest that it may cause degenerative changes at levels immediately above and below the fusion, known as adjacent segment degenerative disease...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28524126/-impact-of-sagittal-balance-parameters-on-life-quality-in-elderly-and-senile-patients-after-surgery-for-degenerative-lumbar-spine-stenosis
#7
V S Klimov, I I Vasilenko, A V Evsyukov, E V Amelina
INTRODUCTION: As the life span and proportion of people over 65 years increase, the incidence of degenerative lumbar spine stenosis grows proportionally. Various parameters of the spinopelvic relationships are used to predict surgical treatment outcomes in patients with degenerative spine diseases. There are no unified protocols for evaluation, in terms of the sagittal balance, of surgical treatment outcomes in elderly patients. PURPOSE: To study the impact of sagittal balance parameters on the life quality of elderly and senile patients after surgery for degenerative stenosis of the lumbar spine...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28503982/anxiety-and-depression-affect-pain-drawings-in-cervical-degenerative-disc-disease
#8
Anna MacDowall, Yohan Robinson, Martin Skeppholm, Claes Olerud
INTRODUCTION: Pain drawings have been frequently used in the preoperative evaluation of spine patients. Until now most investigations have focused on low back pain patients, even though pain drawings are used in neck pain patients as well. The aims of this study were to investigate the pain drawing and its association to preoperative demographics, psychological impairment, and pain intensity. METHODS: We carried out a post hoc analysis of a randomized controlled trial, comparing cervical disc replacement to fusion for radiculopathy related to degenerative disc disease...
May 15, 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28503046/reflections-about-osteoarthritis-and-curcuma-longa
#9
REVIEW
Marina Cristina Akuri, Sandra Maria Barbalho, Raíssa Meira Val, Elen Landgraf Guiguer
Osteoarthritis (OA) is a chronic inflammatory degenerative process that affects joints such as the hands, hips, shoulders, feet, spine, and especially knees in millions of people worldwide. Some authors have shown that Curcuma longa components may exhibit benefic effects in the treatment of degenerative diseases as OA. This plant belongs to the family Zingiberaceae and it is popularly known as turmeric or saffron. This review intended to perform a retrospective search to identify studies involving humans and animal models...
January 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28501956/an-in-vitro-evaluation-of-sagittal-alignment-in-the-cervical-spine-after-insertion-of-supraphysiologic-lordotic-implants
#10
Donald J Blaskiewicz, Jeffrey E Harris, Patrick P Han, Alexander W Turner, Gregory M Mundis
PURPOSE: Cervical spine malalignment can develop as a consequence of degenerative disc disease or following spinal surgery. When normal sagittal alignment of the spine is disrupted, further degeneration may occur adjacent to the deformity. The purpose of this study was to investigate changes in lordosis and sagittal alignment in the cervical spine after insertion of supraphysiologic lordotic implants. METHODS: Eight cadaveric cervical spines (Occiput-T1) were tested...
May 13, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28499438/early-developed-asd-adjacent-segmental-disease-in-patients-after-surgical-treatment-of-the-spine-due-to-cancer-metastases
#11
Grzegorz Guzik
BACKGROUND: The causes of ASD are still relatively unknown. Correlation between clinical status of patients and radiological MRI findings is of primary importance. The radiological classifications proposed by Pfirmann and Oner are most commonly used to assess intradiscal degenerative changes. The aim of the study was to assess the influence of the extension of spine fixation on the risk of developing ASD in a short time after surgery. METHODS: A total of 332 patients with spinal tumors were treated in our hospital between 2010 and 2013...
May 12, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28498069/an-analysis-from-the-quality-outcomes-database-part-2-predictive-model-for-return-to-work-after-elective-surgery-for-lumbar-degenerative-disease
#12
Anthony L Asher, Clinton J Devin, Kristin R Archer, Silky Chotai, Scott L Parker, Mohamad Bydon, Hui Nian, Frank E Harrell, Theodore Speroff, Robert S Dittus, Sharon E Philips, Christopher I Shaffrey, Kevin T Foley, Matthew J McGirt
OBJECTIVE Current costs associated with spine care are unsustainable. Productivity loss and time away from work for patients who were once gainfully employed contributes greatly to the financial burden experienced by individuals and, more broadly, society. Therefore, it is vital to identify the factors associated with return to work (RTW) after lumbar spine surgery. In this analysis, the authors used data from a national prospective outcomes registry to create a predictive model of patients' ability to RTW after undergoing lumbar spine surgery for degenerative spine disease...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28498068/predictors-of-extended-length-of-stay-discharge-to-inpatient-rehab-and-hospital-readmission-following-elective-lumbar-spine-surgery-introduction-of-the-carolina-semmes-grading-scale
#13
Matthew J McGirt, Scott L Parker, Silky Chotai, Deborah Pfortmiller, Jeffrey M Sorenson, Kevin Foley, Anthony L Asher
OBJECTIVE Extended hospital length of stay (LOS), unplanned hospital readmission, and need for inpatient rehabilitation after elective spine surgery contribute significantly to the variation in surgical health care costs. As novel payment models shift the risk of cost overruns from payers to providers, understanding patient-level risk of LOS, readmission, and inpatient rehabilitation is critical. The authors set out to develop a grading scale that effectively stratifies risk of these costly events after elective surgery for degenerative lumbar pathologies...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28486638/predictors-of-discharge-to-a-nonhome-facility-in-patients-undergoing-lumbar-decompression-without-fusion-for-degenerative-spine-disease
#14
Meghan E Murphy, Patrick R Maloney, Brandon A McCutcheon, Lorenzo Rinaldo, Daniel Shepherd, Panagiotis Kerezoudis, Hannah Gilder, Daniel S Ubl, Cynthia S Crowson, Brett A Freedman, Elizabeth B Habermann, Mohamad Bydon
BACKGROUND: Patients recovering from decompressive laminectomy without fusion may require assistance with activities of daily living and physical/occupational therapy upon hospital discharge. OBJECTIVE: To examine comorbidities and perioperative characteristics of patients undergoing lumbar decompression for associations with discharge status using a multicenter database. METHODS: A multicenter database was used for this retrospective cohort analysis...
May 9, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28481388/minimally-invasive-transforaminal-lumbar-interbody-fusion-with-percutaneous-bilateral-pedicle-screw-fixation-for-lumbosacral-spine-degenerative-diseases-a-retrospective-database-of-40-consecutive-treated-cases-and-literature-review
#15
Daniele Francesco Millimaggi, Valerio DI Norcia, Sabino Luzzi, Tommaso Alfiero, Renato Juan Galzio, Alessandro Ricci
AIM: To report our results about minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) with bilateral pedicle screw fixation, in patients with degenerative lumbosacral spine disease. To describe the indications, surgical technique and results of a consecutive series of 40 patients undergone MI-TLIF. Despite the limited number of clinical studies, published data suggest tremendous potential advantages of this technique. MATERIAL AND METHODS: Forty patients with radiological findings of degenerative lumbosacral spine disease were undergone MI-TLIF between July 2012 and January 2015...
April 12, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28467440/serum-biomarkers-in-patients-with-ossification-of-the-posterior-longitudinal-ligament-opll-inflammation-in-opll
#16
Yoshiharu Kawaguchi, Masato Nakano, Taketoshi Yasuda, Shoji Seki, Kayo Suzuki, Yasuhito Yahara, Hiroto Makino, Isao Kitajima, Tomoatsu Kimura
BACKGROUD: Ossification of the posterior longitudinal ligament (OPLL) is characterized by replacement of ligamentous tissue by ectopic new bone formation. OPLL causes narrowing of the spinal canal, resulting in neurological impairment. However, the pathogenesis of OPLL has not been fully elucidated. We investigated whether inflammation occurs in OPLL or not using high-sensitivity CRP (hs-CRP) in a case-control study. METHODS AND FINDINGS: This study included 103 patients with OPLL in the patient group and 95 age- and sex-matched volunteers with degenerative spinal disease in the control group...
2017: PloS One
https://www.readbyqxmd.com/read/28463620/robotic-versus-fluoroscopy-guided-pedicle-screw-insertion-for-metastatic-spinal-disease-a-matched-cohort-comparison
#17
Volodymyr Solomiichuk, Julius Fleischhammer, Granit Molliqaj, Jwad Warda, Awad Alaid, Kajetan von Eckardstein, Karl Schaller, Enrico Tessitore, Veit Rohde, Bawarjan Schatlo
OBJECTIVE Robot-guided pedicle screw placement is an established technique for the placement of pedicle screws. However, most studies have focused on degenerative disease. In this paper, the authors focus on metastatic spinal disease, which is associated with osteolysis. The associated lack of dense bone may potentially affect the automatic recognition accuracy of radiography-based surgical assistance systems. The aim of the present study is to compare the accuracy of the SpineAssist robot system with conventional fluoroscopy-guided pedicle screw placement for thoracolumbar metastatic spinal disease...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28459782/mortality-due-to-surgery-for-degenerative-lumbar-spine
#18
Jyrki Salmenkivi, Reijo Sund, Mika Paavola, Iiris Ruuth, Antti Malmivaara
STUDY DESIGN: Register study. OBJECTIVE: The purpose of this study was to assess the safety of lumbar spine surgery for degenerative disorders and to assess the predictive factors for mortality and causes of death. SUMMARY OF BACKGROUND DATA: Growing numbers and relative indications of spine surgery emphasize the importance of patient safety, We assessed the incidence of mortality related to surgery, overall case fatality and factors predicting mortality in elective spinal surgery...
April 28, 2017: Spine
https://www.readbyqxmd.com/read/28457932/the-role-of-conventional-myelography-in-the-diagnosis-and-treatment-of-degenerative-spine-diseases-in-low-income-communities-a-prospective-study
#19
David Kitya, Maria Punchak, Francis Bajunirwe
INTRODUCTION: Chronic back pain is a common problem and imaging is crucial for effective diagnosis and treatment. In low-resource settings conventional myelography is a cheap alternative to MRI and CT. This study was conducted to re-examine the diagnostic reliability, effectiveness for surgical decision making and safety of conventional myelography. METHODS: The study was conducted at Tenwek Mission Hospital during June 2009 and March 2010. New patients who presented with features of radiculopathy and/or myelopathy were eligible...
April 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28456675/stability-preserving-decompression-in-degenerative-versus-congenital-spinal-stenosis-demographic-patterns-and-patient-outcomes
#20
Philip K Louie, Justin C Paul, Jonathan Markowitz, Joshua A Bell, Bryce A Basques, Alem Yacob, Howard S An
BACKGROUND: Context: Although lumbar spinal stenosis often presents as a degenerative condition, some patients present with symptoms from lifelong narrowing of the spinal canal. These patients have congenital stenosis (CS) and present with symptoms of stenosis at a younger age. CS patients often have a distinct pathophysiology with fewer degenerative changes but present with multi-level involvement. In the setting of neurological symptoms, decompression-alone while preserving stability, has been proposed for both patient populations...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
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