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https://www.readbyqxmd.com/read/28445608/sexual-and-gender-minority-adolescents-views-on-hiv-research-participation-and-parental-permission-a-mixed-methods-study
#1
Brian Mustanski, Ryan Coventry, Kathryn Macapagal, Miriam R Arbeit, Celia B Fisher
CONTEXT: Sexual and gender minority adolescents are underrepresented in HIV research, partly because institutional review boards (IRBs) are reluctant to waive parental permission requirements for these studies. Understanding teenagers' perspectives on parental permission and the risks and benefits of participating in HIV research is critical to informing evidence-based IRB decisions. METHODS: Data from 74 sexual and gender minority adolescents aged 14-17 who participated in an online focus group in 2015 were used to examine perspectives on the risks and benefits of participation in a hypothetical HIV surveillance study and the need for parental permission and adequate protections...
April 26, 2017: Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28445303/lifetime-and-recent-alcohol-use-and-bone-mineral-density-in-adults-with-hiv-infection-and-substance-dependence
#2
Alicia S Ventura, Michael R Winter, Timothy C Heeren, Meg M Sullivan, Alexander Y Walley, Michael F Holick, Gregory J Patts, Seville M Meli, Jeffrey H Samet, Richard Saitz
Low bone mineral density (BMD) is common in people living with HIV infection (PLWH), increasing fracture risk. Alcohol use is also common in PLWH and is a modifiable risk factor for both HIV disease progression and low BMD. In PLWH, alcohol's effect on BMD is not well understood.We studied adult PLWH with substance dependence. We measured lifetime alcohol use (kg) and recent (i.e., past 30-day) alcohol use (categorized as: abstinent, low risk, or high risk). In adjusted multivariable regression analyses, we tested associations between lifetime and recent alcohol use and (i) mean BMD (g/cm) at the femoral neck, total hip, and lumbar spine and (ii) low BMD diagnosis (i...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444529/-we-deserve-better-perceptions-of-hiv-testing-campaigns-among-black-and-latino-msm-in-new-york-city
#3
Kathryn Drumhiller, Ashley Murray, Zaneta Gaul, Tiffiany M Aholou, Madeline Y Sutton, Jose Nanin
In 2014, Black/African-American and Hispanic/Latino men who have sex with men (BLMSM) comprised 64.1% of HIV diagnoses among MSM in the U.S. Routine HIV testing allows earlier diagnosis, linkage to care, and improved health outcomes. HIV testing campaigns may increase HIV awareness and testing behaviors, but perceptions of these campaigns by BLMSM have been understudied. We explored perceptions of HIV testing campaigns with BLMSM in New York City (NYC) to inform campaign strategies that target BLMSM for HIV testing...
April 25, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28444206/the-cost-of-not-re-testing-hiv-misdiagnosis-in-the-art-test-and-offer-era
#4
Jeffrey W Eaton, Cheryl C Johnson, Simon Gregson
We compared estimated costs of re-testing HIV-positive persons before ART initiation to the costs of ART provision to misdiagnosed HIV-negative persons. Savings from averted unnecessary ART costs were greater than re-testing costs within one year using assumptions representative of HIV testing performance in programmatic settings. Countries should implement re-testing before ART initiation.
April 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444006/scale-up-of-collaborative-tb-hiv-activities-in-guyana
#5
Brian J Baker, Brandy Peterson, Jeetendra Mohanlall, Shanti Singh, Collene Hicks, Ruth Jacobs, Ruth Ramos, Barbara Allen, Eric Pevzner
Objective: To assess scale-up of recommended tuberculosis (TB)/HIV activities in Guyana and to identify specific strategies for further expansion. Methods: Medical records and clinic registers were reviewed at nine TB clinics and 10 HIV clinics. At TB clinics, data were collected on HIV testing and antiretroviral therapy (ART) for patients with TB/HIV; at HIV clinics, data were collected on intensified case finding (ICF), tuberculin skin test (TST) results, and provision of isoniazid preventive therapy (IPT)...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28443275/integration-of-hiv-testing-into-maternal-newborn-and-child-health-weeks-for-improved-case-finding-and-linkage-to-prevention-of-mother-to-child-transmission-services-in-benue-state-nigeria
#6
Olusoji Akinleye, Gideon Dura, Arjan de Wagt, Abiola Davies, Dick Chamla
BACKGROUND: In Nigeria, maternal, newborn, and child health (MNCH) weeks are campaign-like events designed to accelerate progress toward Millennium Development Goals. The authors examined whether integrating HIV testing into MNCH weeks was feasible and could lead to increased case finding and linkage to prevention of mother-to-child transmission (PMTCT) services. METHODS: Pregnant women attending MNCH week during the first week of December 2014 in 13 local government areas in Benue State were provided with HIV tests and referrals to PMTCT services...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28442797/pre-and-post-sexual-exposure-prophylaxis-of-hiv-an-update
#7
REVIEW
Yogesh S Marfatia, Sheethal K Jose, Reema R Baxi, Ruchi J Shah
Pitfalls in current HIV prevention strategies include late HIV testing, vulnerability among youth and females; lack of emphasis on treatment, low acceptance of circumcision, and nonavailability of protective vaccines. Continuing high-risk sexual behavior, forceful sex, coercive and nonconsensual sex, rape, and unprotected sexual activities make women the most vulnerable to acquisition of sexually transmitted infection/HIV and necessitates a more radical approach of prevention in high-risk individuals who do not have HIV...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28441975/seek-test-treat-substance-using-women-in-the-hiv-treatment-cascade-in-south-africa
#8
Wendee M Wechsberg, Charles van der Horst, Jacqueline Ndirangu, Irene A Doherty, Tracy Kline, Felicia A Browne, Jennifer M Belus, Robin Nance, William A Zule
BACKGROUND: Women in South Africa who use alcohol and other drugs face multiple barriers to HIV care. These barriers make it difficult for women to progress through each step in the HIV treatment cascade from diagnosis to treatment initiation and adherence. This paper examines correlates of HIV status, newly diagnosed HIV status, and use of antiretroviral therapy (ART). METHODS: Outreach workers recruited sexually active Black African women who used substances in Pretoria as part of a U...
April 26, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/28439755/what-do-key-stakeholders-think-about-hiv-self-testing-in-canada-results-from-a-cross-sectional-survey
#9
N Pant Pai, M Smallwood, D Gulati, N Lapczak, A Musten, C Gaydos, C Johnston, M Steben, T Wong, N Engel, J Kim
Human immunodeficiency virus (HIV) self-testing presents an empowering alternative to facility-based testing for reaching undiagnosed HIV infected individuals, but is not currently available in Canada. We surveyed stakeholders (clinical providers, public health professionals, researchers) engaged in HIV testing initiatives nationwide to identify the concerns, opportunities and challenges to implementing HIV self-testing in Canada. An online cross-sectional survey was disseminated by the Canadian Institutes of Health Research Centre for REACH 2...
April 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28438144/development-and-effectiveness-of-a-mobile-phone-application-conducting-health-behavioral-intervention-among-men-who-have-sex-with-men-a-randomized-controlled-trial-study-protocol
#10
Jin Yan, Aidi Zhang, Liang Zhou, Zhulin Huang, Pan Zhang, Guoli Yang
BACKGROUND: Behavioral intervention is a key approach to HIV prevention among men who have sex with men (MSM). Widespread use of mobile phones provide us with novel opportunities to decrease HIV infection and transmission of MSM. The objective of the study was to design and develop a mobile phone application (app) aims to conduct behavioral intervention to MSM and to evaluate the efficacy of the app-based intervention compared to usual care, to analyze cost-effectiveness and mechanism of the intervention...
April 24, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28438139/digital-cxr-with-computer-aided-diagnosis-versus-symptom-screen-to-define-presumptive-tuberculosis-among-household-contacts-and-impact-on-tuberculosis-diagnosis
#11
Monde Muyoyeta, Nkatya Chanda Kasese, Deborah Milimo, Isaac Mushanga, Mapopa Ndhlovu, Nathan Kapata, Maureen Moyo-Chilufya, Helen Ayles
BACKGROUND: Household (HH) contact tracing is a strategy that targets high risk groups for TB. Symptom based screening is the standard used to identify HH contacts at risk for TB during HH contact tracing for TB. However, this strategy may be limited due to poor performance in predicting TB. The objective of this study was to compare CXR with Computer Aided Diagnosis (CAD) against symptom screen for defining presumptive TB and how TB detection changes with each method. METHODS: Household contacts of consecutive index bacteriologically confirmed TB cases were visited by study teams and given TB/HIV education to raise awareness of the risk of TB following close contact with a TB patient...
April 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28436276/should-trained-lay-providers-perform-hiv-testing-a-systematic-review-to-inform-world-health-organization-guidelines
#12
C E Kennedy, P T Yeh, C Johnson, R Baggaley
New strategies for HIV testing services (HTS) are needed to achieve UN 90-90-90 targets, including diagnosis of 90% of people living with HIV. Task-sharing HTS to trained lay providers may alleviate health worker shortages and better reach target groups. We conducted a systematic review of studies evaluating HTS by lay providers using rapid diagnostic tests (RDTs). Peer-reviewed articles were included if they compared HTS using RDTs performed by trained lay providers to HTS by health professionals, or to no intervention...
April 24, 2017: AIDS Care
https://www.readbyqxmd.com/read/28435311/application-of-bayesian-decision-making-to-laboratory-testing-for-lyme-disease-and-comparison-with-testing-for-hiv
#13
Michael J Cook, Basant K Puri
In this study, Bayes' theorem was used to determine the probability of a patient having Lyme disease (LD), given a positive test result obtained using commercial test kits in clinically diagnosed patients. In addition, an algorithm was developed to extend the theorem to the two-tier test methodology. Using a disease prevalence of 5%-75% in samples sent for testing by clinicians, evaluated with a C6 peptide enzyme-linked immunosorbent assay (ELISA), the probability of infection given a positive test ranged from 26...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28434809/real-world-performance-of-the-new-us-hiv-testing-algorithm-in-medical-settings
#14
Kara G Marson, Robert Marlin, Phong Pham, Stephanie E Cohen, Diane Jones, Marguerite Roemer, Philip J Peters, Barbara Haller, Christopher D Pilcher
BACKGROUND: Our medical center laboratory recently adapted its 24/7, two-hourly testing program to use an ARCHITECT-Multispot-viral load (AR-MS-VL) algorithm in place of a previous rapid test-immunofluorescence (RT-IF) algorithm. OBJECTIVES: We evaluated screening test performance, acute case detection, turnaround time and ability to resolve HIV status under the new algorithm. STUDY DESIGN: We considered consecutive HIV tests from January to November 2015...
April 7, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28434253/risky-sexual-behaviors-as-correlates-of-depression-and-suicidal-ideation-among-male-hiv-test-seekers-at-a-voluntary-counseling-and-testing-facility-in-taiwan
#15
Chia-Chun Lin, Yuan-Ti Lee, Hao-Jan Yang
This study aims at determining the level of depression and suicidal status of adult HIV test-seekers. Of the total enrolled 850 males, almost 50% reported some risk behaviors, 38.9% experienced depression, and 7.2% had suicidal ideation. Subjects with risky sexual behaviors in terms of repeated HIV test, had a history of sexually transmitted disease, engaged in one-night stands, or did not use condoms all the time with causal sexual partners were more likely to have depression. Furthermore, subjects who were bisexual/homosexual, engaged in Internet sex, engaged in one-night stands, or used addictive drugs within the past 6 months were more likely to experience suicidal ideation...
April 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28432549/factors-associated-with-hpv-vaccination-in-young-males
#16
Kelli M Fuller, Leslie Hinyard
Human papilloma virus (HPV) affects both men and women; however, recommendations for HPV vaccination among men were not issued in the United States until 2011. The purpose of this study was to describe and compare characteristics of men who did and did not report receiving at least one dose of the HPV vaccine. Data from the ten states that completed the HPV vaccination module in the 2013 Behavioral Risk Factor Surveillance System (BRFSS) were included in the study. Young men ages 18-26 were included (N = 1624)...
April 21, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28428187/zambian-peer-educators-for-hiv-self-testing-zest-study-rationale-and-design-of-a-cluster-randomised-trial-of-hiv-self-testing-among-female-sex-workers-in-zambia
#17
Catherine E Oldenburg, Katrina F Ortblad, Michael M Chanda, Kalasa Mwanda, Wendy Nicodemus, Rebecca Sikaundi, Andrew Fullem, Leah G Barresi, Guy Harling, Till Bärnighausen
BACKGROUND: HIV testing and knowledge of status are starting points for HIV treatment and prevention interventions. Among female sex workers (FSWs), HIV testing and status knowledge remain far from universal. HIV self-testing (HIVST) is an alternative to existing testing services for FSWs, but little evidence exists how it can be effectively and safely implemented. Here, we describe the rationale and design of a cluster randomised trial designed to inform implementation and scale-up of HIVST programmes for FSWs in Zambia...
April 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28426440/the-impact-of-couple-hiv-testing-and-counseling-on-consistent-condom-use-among-pregnant-women-and-their-male-partners-an-observational-study
#18
Nora E Rosenberg, Lauren A Graybill, Austin Wesevich, Nuala McGrath, Carol E Golin, Suzanne Maman, Nivedita Bhushan, Mercy Tsidya, Limbikani Chimndozi, Irving F Hoffman, Mina C Hosseinipour, William C Miller
BACKGROUND: In sub-Saharan Africa couple HIV testing and counseling (CHTC) has been associated with substantial increases in safe sex, especially when at least one partner is HIV-infected. However, this relationship has not been characterized in an Option B+ context. SETTING: The study was conducted at the antenatal clinic at Bwaila District Hospital in Lilongwe, Malawi in 2016 under an Option B+ program. METHODS: Ninety heterosexual couples with an HIV-infected pregnant woman (female-positive couples) and 47 couples with an HIV-uninfected pregnant woman (female-negative couples) were enrolled in an observational study...
April 18, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28426301/small-group-randomized-controlled-trial-to-increase-condom-use-and-hiv-testing-among-hispanic-latino-gay-bisexual-and-other-men-who-have-sex-with-men
#19
Scott D Rhodes, Jorge Alonzo, Lilli Mann, Eunyoung Y Song, Amanda E Tanner, Jorge Elias Arellano, Rodrigo Rodriguez-Celedon, Manuel Garcia, Arin Freeman, Beth A Reboussin, Thomas M Painter
OBJECTIVES: To evaluate the HOLA en Grupos intervention, a Spanish-language small-group behavioral HIV prevention intervention designed to increase condom use and HIV testing among Hispanic/Latino gay, bisexual, and other men who have sex with men. METHODS: In 2012 to 2015, we recruited and randomized 304 Hispanic/Latino men who have sex with men, aged 18 to 55 years in North Carolina, to the 4-session HOLA en Grupos intervention or an attention-equivalent general health education comparison intervention...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28425903/improving-linkage-to-hiv-care-at-low-threshold-sti-hiv-testing-sites-an-evaluation-of-the-immediate-staging-pilot-project-in-vancouver-british-columbia
#20
Bobbi Brownrigg, Darlene Taylor, Felicia Phan, Irvine Sandstra, Rochelle Stimpson, Rolando Barrios, Richard Lester, Gina Ogilvie
OBJECTIVES: The objective of the Immediate Staging Pilot Project (ISPP) was to improve linkage to human immunodeficiency virus (HIV) care by increasing the number of referrals made to HIV care, and to decrease the time between diagnosis and linkage to care for newly diagnosed HIV clients. This pilot had the potential to decrease HIV transmission at a population level by engaging clients in treatment earlier. SETTING: The Bute Street Clinic and Health Initiative for Men Clinic on Davie in Vancouver, British Columbia are low-threshold public health facilities providing HIV/STI testing primarily to men who have sex with men (MSM)...
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
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