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Mineral trioxide aggregate

Triantafyllia Vouzara, Garyfallia Dimosiari, Elisabeth A Koulaouzidou, Nikolaos Economides
INTRODUCTION: Resin sealers with biocompatible and bioactive additives have been used in clinical practice. Recently, a calcium silicate root canal sealer was introduced under the name BioRoot RCS (Septodont, Saint Maur-des-Fossés, France). The aim of this study was to evaluate the effects of BioRoot RCS on cell survival and proliferation of cultured cells in parallel with an epoxy resin sealer with calcium phosphate and calcium oxide and a salicylate resin sealer with mineral trioxide aggregate filler...
March 14, 2018: Journal of Endodontics
Roshan Noor Mohamed, Sakeenabi Basha, Yousef Al-Thomali
The main purpose of the present systematic review was to evaluate the efficacy of platelet concentrates in pulpotomy of human teeth. Our systematic search included Medline, Embase, CINAHL, PsycINFO, Scopus, key journals, and review articles; the date of the last search was July 30, 2017. We graded the methodological quality of the studies by Cochrane Risk of Bias tool. Four randomized controlled trails were included in the present systematic review. The number of study participants ranged from 28 to 50, with a mean of 45...
March 14, 2018: Platelets
Prasad K Musale, Sneha S Kothare, Abhishek S Soni
This narrative aims at reviewing the available literature for mineral trioxide aggregate (MTA) pulpotomy to understand the procedure better and eventually improve the clinical and radiographic outcomes. An electronic search was conducted in PubMed, Cochrane, ScienceDirect and ClinicalKey databases with the following keywords: MTA pulpotomy, clinical outcomes, radiographic outcomes, primary teeth. No specific inclusion or exclusion criteria were applied as to what articles would be included in this review. The time period for the search began from 2001 with respect to MTA pulpotomy...
2018: Clinical, Cosmetic and Investigational Dentistry
F Tirone, S Salzano, A Piattelli, V Perrotti, G Iezzi
OBJECTIVES: The aim of this study was to investigate for the first time the histological response of periodontium to mineral trioxide aggregate (MTA) and Biodentine in human experimental models. MATERIALS AND METHODS: Six patients scheduled for implant full-arch rehabilitation via the all-on-4 technique were randomly assigned to one of the two test groups: either to MTA or Biodentine treatment. For each patient, 2 teeth scheduled for strategic extraction were randomly assigned either to the test or to the control treatment...
March 6, 2018: Australian Dental Journal
Gary Alex
Among the goals of pulp capping are to manage bacteria, arrest caries progression, stimulate pulp cells to form new dentin, and produce a durable seal that protects the pulp complex. This article will provide a general discussion of direct and indirect pulp capping procedures, offering practitioners a pragmatic and science-based clinical protocol for treatment of vital pulp exposures. A clinical case will be presented in which a novel light-cured resin-modified mineral trioxide aggregate hybrid material was used to manage a mechanical vital pulp exposure that occurred during deep caries excavation...
March 2018: Compendium of Continuing Education in Dentistry
Teresa Marggraf, Petra Ganas, Sebastian Paris, Falk Schwendicke
Sealing can arrest caries lesions. We aimed to evaluate if sealing effects and kinetics are bacterial-strain and sealing-material specific. Human dentin discs were mounted in a dual-chamber device. Caries lesions were induced chemically and contaminated with either Lactobacillus rhamnosus (LR) or Streptococcus sobrinus (SS). For (1) kinetics assessment, the initial bacterial load and the sealing period were varied, and lesions sealed using a self-etch adhesive and composite. For (2) comparing materials, six sealing protocols (#1-#6) were evaluated: 1# Self-etch adhesive plus composite placed without a liner, or #2 calcium hydroxide, or #3 mineral trioxide aggregate, or #4 Biodentine liners; #5 antibacterial adhesive plus composite; #6 glass ionomer cement...
February 28, 2018: Scientific Reports
G L Dou, N Wu, S Y Zhao, B Xia
OBJECTIVE: To evaluate the two-year outcomes of primary molars pulpotomy using mineral trioxided aggregate (MTA) and to find out the potential influence factor, with the help of electronic medical record database. METHODS: Children who received primary molars pulpotomy in the Department of Pediatric Dentistry in Peking University School and Hospital of Stomatology from May, 2014 to November, 2015 were searched in the Electronic Medical Record Database of Peking University School and Hospital of Stomatology, via the database for scientific research provided by the corporation of Kaientai...
February 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
K X Xie, Y G Li, P Zhang, X Wang
OBJECTIVE: To evaluate the effect of acid etching of retropreps on seal of different retrofill materials. METHODS: In the study, 80 freshly extracted lower molar teeth were used. They were examined under 3.5× magnifying glass to rull out fractures. They were cleaned and stored in distilled water before use. The distal roots were sectioned off and underwent root canal treatment. Rotary nickel-titanium instruments were used during instrumentation and the roots were obturated using lateral condensation technique...
February 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Y T Dong, F C Tian, B Jia, B Zu, X Y Wang
OBJECTIVE: To investigate influence of setting time on bond strength of different bioactive pulp capping materials with self-etch or etch-and-rinse adhesive. METHODS: Sixty specimens were prepared for each of the three tested capping materials, namely mineral trioxide aggregate (MTA), iRoot BP Plus (BP) and iRoot FS (FS). Specimens of each material were divided into three groups and bonded at three setting time points of the materials respectively: initial setting time (4 h for MTA, 2 h for BP and 20 min for FS), 24 h after application and 7 d after application...
February 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Omid Dianat, Fatemeh Mashhadiabbas, Zohreh Ahangari, Sara Saedi, Saeed Reza Motamedian
Previous in vitro studies have suggested that simvastatin can be used as a direct pulp capping material due to its ability to induce odontoblastic differentiation and angiogenesis. The aim of this animal study was to evaluate the pulpal response to mineral trioxide aggregate (MTA) and four concentrations of simvastatin/MTA in combination. The study was conducted in two stages using four different simvastatin concentrations and MTA as a capping material for rat maxillary molars. The grades of inflammation and continuity of dentin formation were evaluated in hematoxylin and eosin (HE)-stained samples...
February 26, 2018: Journal of Oral Science
Selen Küçükkaya Eren, Peter Parashos
This systematic review analysed the literature comparing marginal adaptation of mineral trioxide aggregate (MTA) with other filling materials in root-end cavities. The PubMed, Ovid, Web of Science, SCOPUS, and Cochrane library databases were searched using appropriate keywords related to root-end filling materials and adaptation. Of 38 articles assessed, 20 met the inclusion criteria. No in vivo study was identified. In 10 studies, MTA gave the best marginal adaptation results, but no significant differences were found between MTA and any of the tested filling materials in seven studies...
February 16, 2018: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
Liliana Argueta-Figueroa, José J Delgado-García, René García-Contreras, Omar Martínez-Alvarez, José Santos-Cruz, Carlos Oliva-Martínez, Laura S Acosta-Torres, Javier de la Fuente-Hernández, Ma C Arenas-Arrocena
The purpose of this study was to characterize mineral trioxide aggregates (MTA) enriched with iron disulfide (FeS2) nanostructures at different concentrations, and to investigate their storage modulus, radiopacity, setting time, pH, cytotoxicity, and antimicrobial activity. Iron disulfide nanostructures [with particle size of 0.357 ± 0.156 μm (mean ± SD)] at weight ratios of 0.2, 0.4, 0.6, 0.8, and 1.0 wt% were added to white MTA (wMTA). The radiopacity, rheological properties, setting time, and pH, as well as the cytotoxicity (assessed using the MTT assay) and antibacterial activity (assessed using the broth microdilution test) were determined for MTA/FeS2nanostructures...
February 14, 2018: European Journal of Oral Sciences
Amber A Miller, Koyo Takimoto, James Wealleans, Anibal Diogenes
INTRODUCTION: There is a complex interaction between biomaterials placed as a coronal barrier with stem cells and dentin in regenerative procedures. In this study, the effect of Biodentine (BD; Septodont, Saint-Maurdes-Fossés, France), Endosequence BC Root Repair Material-Putty (ES; Brasseler, Savannah, GA), Endosequence BC Root Repair Material-Putty Fast set (ES-fast, Brasseler), and ProRoot (Dentsply Tulsa Dental Specialties, Johnson City, TN) mineral trioxide aggregate (MTA) on the viability and differentiation of stem cells of the apical papilla (SCAP) was evaluated using an ex vivo dentin disk model...
February 6, 2018: Journal of Endodontics
Leandro Borges Araújo, Leopoldo Cosme-Silva, Ana Paula Fernandes, Thais Marchini de Oliveira, Bruno das Neves Cavalcanti, João Eduardo Gomes Filho, Vivien Thiemy Sakai
The aim of the study was to evaluate the effects of the capping materials mineral trioxide aggregate (MTA), calcium hydroxide (CH) and BiodentineTM (BD) on stem cells from human exfoliated deciduous teeth (SHED) in vitro. SHED were cultured for 1 - 7 days in medium conditioned by incubation with MTA, BD or CH (1 mg/mL), and tested for viability (MTT assay) and proliferation (SRB assay). Also, the migration of serum-starved SHED towards conditioned media was assayed in companion plates, with 8 μm-pore-sized membranes, for 24 h...
February 1, 2018: Journal of Applied Oral Science: Revista FOB
Amin Salem-Milani, Saeede Ghasemi, Saeed Rahimi, Amir Ardalan-Abdollahi, Mohammad Asghari-Jafarabadi
Background: The aim of this study was to evaluate the discoloration induced by CEM cement, Portland cement (PC) and MTA mixed with propylene glycol (MTA-PG) in comparison to White MTA. Material and Methods: Ninety extracted premolar and canine teeth were resected 2 mm below the CEJ. The coronal part of crown was prepared with peeso reamer and Gates-Glidden drills, and the specimens were randomly divided into 4 experimental (n=20) and one control (n=10) groups. The tooth crowns in experimental groups 1 to 4 were filled with White MTA, PC, CEM cement and MTA-PG, respectively; and in group 5, the teeth were kept empty...
December 2017: Journal of Clinical and Experimental Dentistry
S Proksch, J Brossart, K Vach, E Hellwig, M J Altenburger, L Karygianni
AIM: To investigate if a combination of mineral trioxide aggregate (MTA) and fluoride compounds affects bone cells. METHODOLOGY: MTA discs (ProRoot® , Dentsply Sirona, Ballaigues, Switzerland) with and without addition of 0.1%, 0.25%, and 0.5% sodium fluoride were characterized for their surface roughness by laser scanning microscopy and for the adhesion of human alveolar osteoblasts by scanning electron microscopy. Using eluates from fluoride-enriched MTA discs, the cell proliferation was measured by monitoring the DNA incorporation of 5-bromo-2'-deoxyuridine...
February 3, 2018: International Endodontic Journal
Bor-Shiunn Lee, Hong-Ping Lin, Jerry Chun-Chung Chan, Wei-Chuan Wang, Ping-Hsuan Hung, Yu-Hsin Tsai, Yuan-Ling Lee
Mineral trioxide aggregate (MTA) is the most frequently used repair material in endodontics, but the long setting time and reduced mechanical strength in acidic environments are major shortcomings. In this study, a novel sol-gel-derived calcium silicate cement (sCSC) was developed using an initial Ca/Si molar ratio of 3, with the most effective mixing orders of reactants and optimal HNO3 catalyst volumes. A Fourier transform infrared spectrometer, scanning electron microscope with energy-dispersive X-ray spectroscopy, and X-ray powder diffractometer were used for material characterization...
2018: International Journal of Nanomedicine
Shilpa Shetty, Geeta Hiremath, Mahantesh Yeli
Aim of the Study: The aim of this study was to compare and evaluate the sealing ability of four root end filling materials mineral trioxide aggregate (MTA)-Plus, Biodentine, MTA (MTA Angelus) and glass ionomer cement (GIC) using fluid filtration method. Materials and Methods: Forty-four extracted, human single-rooted teeth were collected. The crown of each tooth was decoronated 2 mm above the cementoenamel junction. Canals were negotiated, instrumented, obturated using lateral compaction method...
September 2017: Journal of Conservative Dentistry: JCD
Fatih Tulumbaci, Merve Erkmen Almaz, Volkan Arikan, Merve Safa Mutluay
Significance of Study: Mineral trioxide aggregate (MTA) and Biodentine (calcium silicate-based materials) have great importance in dentistry. There is no study comparing the bond strength of Biodentine and MTA for composite, compomer, and compomer or resin-modified glass ionomer (RMGIC). Although many advantages of Biodentine over MTA; in this study, MTA has shown better shear bond strength (SBS) to restorative materials. Aim: Recently, a variety of calcium silicate-based materials are often used for pulp capping, perforation repair, and endodontic therapies...
September 2017: Journal of Conservative Dentistry: JCD
O Carti, F Oznurhan
OBJECTIVES: Pulpotomy is the common therapy for cariously exposed pulps in symptom-free primary molar teeth. For many years, researchers have searched for an ideal material that allows regeneration of the residual pulp. The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA), Biodentine as a pulpotomy medicament in primary teeth, both clinically and radiographically. MATERIALS AND METHODS: A total of 25 children (50 human primary molar teeth) aged between 5 and 9 years were selected in this randomized clinical study...
December 2017: Nigerian Journal of Clinical Practice
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