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https://www.readbyqxmd.com/read/27912753/radiographic-evaluation-of-early-periprosthetic-acetabular-bone-contrast-and-prosthetic-head-acetabular-coverage-after-uncemented-and-cemented-total-hip-prosthesis-in-dogs
#1
Ayman A Mostafa, Karin Lucas, Ingo Nolte, Patrick Wefstaedt
BACKGROUND: Coxofemoral osteoarthritis is a chronic, disabling condition affecting people and dogs, with THA providing an excellent return to function in severely affected joints. The principal role of THA is to restore an adequate range of motion to the hip joint while transferring load from the acetabulum in order to improve the survival of the implant and enhance the limb function in the short and long terms. The objectives of the study reported here were, therefore, to radiographically evaluate periprosthetic acetabular bone GV and to assess prosthetic head acetabular coverage after 4 months of uncemented and cemented THA in dogs...
December 3, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27903837/the-effect-of-army-vest-design-on-the-occurrence-of-stress-fractures-and-overuse-injuries-in-female-military-recruits
#2
Ezequiel Palmanovich, M Frankl, M Nyska, I Hetsroni, N Constantini, L Trejo, R Bechar, G Novak, Z Lankovsky, G Mann
INTRODUCTION: Stress fractures (SFs) occur when microdamage caused by repetitive mechanical load exceeds the biological load-bearing capacity of the bone. The study objective was to test whether a vest specifically designed and manufactured for female recruits, compared with the standard vest used on a regular basis by Border Police recruits, would reduce the incidence of SF in female Border Police recruits. Data based on reports of military personnel show that women are more likely to sustain SFs...
November 30, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27900541/tendon-transfer-to-unossified-bone-in-a-porcine-model-potential-implications-for-early-tibialis-anterior-tendon-transfers-in-children-with-clubfeet
#3
Matthew A Halanski, Sam Abrams, Rachel Lenhart, Ellen Leiferman, Teresa Kaiser, Emily Pierce, Rachel Rebekah Franklin, Dayton Opel, Kenneth J Noonan, Thomas D Crenshaw
PURPOSE: Tibialis anterior tendon transfers (TATT) are commonly performed in young children following Ponseti casting for clubfeet. The classic TATT involves advancing the tendon through a hole drilled in the ossified cuneiform. The aim of this study was to determine if tendons transferred through unossified bones have untoward effects on subsequent bone development. METHOD: Twenty-five piglets underwent one of five surgical procedures. An 18-gauge needle was then used to place a tunnel through the bony or cartilaginous portion of the calcaneus (through direct visualization) and isolated slips of the flexor digitorum superficialis (FDS) were placed through the tunnels, as determined by surgical procedure...
November 30, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27896266/in-vitro-bone-cell-models-impact-of-fluid-shear-stress-on-bone-formation
#4
REVIEW
Claudia Wittkowske, Gwendolen C Reilly, Damien Lacroix, Cecile M Perrault
This review describes the role of bone cells and their surrounding matrix in maintaining bone strength through the process of bone remodeling. Subsequently, this work focusses on how bone formation is guided by mechanical forces and fluid shear stress in particular. It has been demonstrated that mechanical stimulation is an important regulator of bone metabolism. Shear stress generated by interstitial fluid flow in the lacunar-canalicular network influences maintenance and healing of bone tissue. Fluid flow is primarily caused by compressive loading of bone as a result of physical activity...
2016: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/27894941/one-year-of-abaloparatide-a-selective-peptide-activator-of-the-pth1-receptor-increased-bone-mass-and-strength-in-ovariectomized-rats
#5
Aurore Varela, Luc Chouinard, Elisabeth Lesage, Robert Guldberg, Susan Y Smith, Paul J Kostenuik, Gary Hattersley
Abaloparatide is a novel 34 amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor 1 (PTHR1) signaling pathway. The effects of 12months of abaloparatide treatment on bone mass, bone strength and bone quality was assessed in osteopenic ovariectomized (OVX) rats. SD rats were subjected to OVX or sham surgery at 6months of age and left untreated for 3months to allow OVX-induced bone loss. Eighteen OVX rats were sacrificed after this bone depletion period, and the remaining OVX rats received daily s...
November 25, 2016: Bone
https://www.readbyqxmd.com/read/27894544/effect-of-longitudinal-flutes-on-miniscrew-implant-stability-and-3-dimensional-bone-formation
#6
Peter An V Truong, Phillip M Campbell, Elias D Kontogiorgos, Reginald W Taylor, Hee-Moon Kyung, Peter H Buschang
INTRODUCTION: The purpose of this study was to evaluate the effects of longitudinal flutes on miniscrew implant (MSI) stability and bone healing. METHODS: Using 11 skeletally mature New Zealand white rabbits, we placed 31 longitudinally fluted and 31 nonfluted, 3-mm-long MSIs in standardized positions in their calvaria and immediately loaded them with 100 g using nickel-titanium coil springs. Insertion torque values were obtained for each MSI placed; removal torque values were obtained for 28 MSIs that had been in place for 6 weeks and 20 MSIs that had been in place for 2 weeks...
December 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27892717/dental-implants-modified-with-drug-releasing-titania-nanotubes-therapeutic-potential-and-developmental-challenges
#7
Karan Gulati, Sašo Ivanovski
The trans-mucosal nature of dental implants presents a unique therapeutic challenge, requiring not only rapid establishment and subsequent maintenance of osseointegration, but also the formation of resilient soft tissue integration. Key challenges in achieving long-term success are sub-optimal bone integration in compromised bone conditions and impaired trans-mucosal tissue integration in the presence of a persistent oral microbial biofilm. These challenges can be targeted by employing a drug-releasing implant modification such as TiO2 nanotubes (TNTs), engineered on titanium surfaces via electrochemical anodization...
November 28, 2016: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/27885183/-osteoporosis-and-mechano-biosciences
#8
Toshio Matsumoto
Mechanical unloading due to long-term bedrest or microgravity during spaceflight causes a devastating influence on bone. Although bisphosphonates can prevent bone loss and hypercalciuria by mechanical unloading for up to 6 months, the influence of unloading for longer period of time is unknown. This is because mechanical loading is one of the most important stimuli for bone formation. Mechanical stress activates several intracellular signaling pathways. Among them, activation of stress-activated cation channel by fluid shear stress stimulates ERK-CREB signaling to enhance the expression of fos family transcription factors, which stimulates IL-11 expression in osteoblastic cells...
2016: Clinical Calcium
https://www.readbyqxmd.com/read/27871820/enhanced-bone-formation-in-sheep-vertebral-bodies-after-minimally-invasive-treatment-with-a-novel-plga-fiber-reinforced-brushite-cement
#9
Stefan Maenz, Olaf Brinkmann, Elke Kunisch, Victoria Horbert, Francesca Gunnella, Sabine Bischoff, Harald Schubert, Andre Sachse, Long Xin, Jens Günster, Bernhard Illerhaus, Klaus D Jandt, Jörg Bossert, Raimund W Kinne, Matthias Bungartz
BACKGROUND: Injectable, brushite-forming calcium phosphate cements (CPC) show potential for bone replacement, but they exhibit low mechanical strength. This study tested a CPC reinforced with poly (l-lactide-co-glycolide) acid (PLGA) fibers in a minimally-invasive, sheep lumbar vertebroplasty model. PURPOSE: To test the in vivo biocompatibility and osteogenic potential of a PLGA fiber-reinforced, brushite-forming CPC in a sheep large animal model. STUDY DESIGN/SETTING: Prospective experimental animal study METHODS: Bone defects (diameter 5 mm) were placed in aged, osteopenic female sheep and left empty (L2) or injected with pure CPC (L3) or PLGA-fiber-reinforced CPC (L4; fiber diameter 25 µm; length 1 mm; 10% (w/w))...
November 15, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27867669/simplifying-the-treatment-of-bone-atrophy-in-the-posterior-regions-combination-of-zygomatic-and-wide-short-implants-a-case-report-with-2-years-of-follow-up
#10
Fernanda Faot, Geninho Thomé, Amália Machado Bielemann, Caio Hermann, Ana Cláudia Moreira Melo, Luis Eduardo Marques Padovan, Ivete Aparecida de Mattias Sartori
The rehabilitation of maxillary and mandibular bone atrophy represents one of the main challenges of modern oral implantology because it requires a variety of procedures, which not only differ technically, but also differ in their results. In the face of limitations such as deficiencies in the height and thickness of the alveolar structure, prosthetic rehabilitation has sought to avoid large bone reconstruction through bone grafting; this clinical behavior has become a treatment system based on evidence from clinical scientific research...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27861662/long-term-outcomes-of-immediate-loading-of-short-implants-a-controlled-retrospective-cohort-study
#11
Eduardo Anitua, Javier Flores, Carlos Flores, Mohammad Hamdan Alkhraisat
PURPOSE: Short implants (≤ 8.5 mm in length) have presented predictable outcomes. However, there is paucity in the long-term evaluation of immediate loading of short implants. The objective of this study was to assess the effect of the immediate loading of short implants on treatment outcomes. MATERIALS AND METHODS: Patients having short implants inserted before December 2010 that were immediately loaded were selected. A database was then created to include the patient's data as well as implant- and prostheses-related outcomes...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27860171/long-term-effect-of-surface-roughness-and-patients-factors-on-crestal-bone-loss-at-dental-implants-a-systematic-review-and-meta-analysis
#12
REVIEW
Ron Doornewaard, Véronique Christiaens, Hugo De Bruyn, Magnus Jacobsson, Jan Cosyn, Stijn Vervaeke, Wolfgang Jacquet
Publications from 2011 to 2015 were selected to evaluate effect of implant surface roughness on long-term bone loss as surrogate for peri-implantitis risk. 87 out of 2,566 papers reported the mean bone loss after at least 5 years of function. Estimation of the proportion of implants with bone loss above 1, 2, and 3 mm as well as analysis the effect of implant surface roughness, smoking, and history of periodontitis was performed. By means of the provided statistical information of bone loss (mean and standard deviation) the prevalence of implants with bone loss ranging from 1 to 3 mm was estimated...
November 15, 2016: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/27846265/sexual-dimorphism-of-the-human-tibia-through-time-insights-into-shape-variation-using-a-surface-based-approach
#13
Hana Brzobohatá, Václav Krajíček, Zdeněk Horák, Jana Velemínská
In this paper we present a three-dimensional (3D) morphometrical assessment of human tibia sexual dimorphism based on whole bone digital representation. To detect shape-size and shape differences between sexes, we used geometric morphometric tools and colour-coded surface deviation maps. The surface-based methodology enabled analysis of sexually dimorphic features throughout the shaft and articular ends of the tibia. The overall study dataset consisted of 183 3D models of adult tibiae from three Czech population subsets, dating to the early medieval (9-10th century) (N = 65), early 20th century (N = 61) and 21st-century (N = 57)...
2016: PloS One
https://www.readbyqxmd.com/read/27843505/influence-of-implant-design-cylindrical-and-conical-in-the-load-transfer-surrounding-long-13mm-and-short-7mm-length-implants-a-photoelastic-analysis
#14
Sergio Alexandre Gehrke, Victor Lourenço Frugis, Jamil Awad Shibli, Maria Piedad Ramirez Fernandez, José Eduardo Maté Sánchez de Val, José Luis Calvo Girardo, Silvio Taschieri, Stefano Corbella
PURPOSE: This study compared the influence of implant design (cylindrical and conical) in the load transfer on bone surrounding 13mm and 7mm length implants under simulated occlusal loading, using photoelastic analysis. METHOD: Dental implants of 4mm diameter were divided into four groups, which varied in length and design: Group 1- standard (13 mm) cylindrical implant; Group 2 - standard conical implant; Group 3 - short (7 mm) cylindrical implant, and Group 4 - short conical implant...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27834448/tibial-revision-knee-arthroplasty-influence-of-modular-stems-on-implant-fixation-and-bone-flexibility-in-aori-type-t2a-defects
#15
Jan Nadorf, Simone Gantz, Konner Kohl, Jan P Kretzer
BACKGROUND: Due to the varying bone defects presented to surgeons during revision total knee arthroplasty, modular implant systems are preferred over standard implant designs. However, every implant combination (sleeves, stems and augments) can affect the fixation in different ways and thus influence the long-term outcome. We therefore aimed to analyze the effect of large metaphyseal sleeves with and without short modular stems on implant fixation and bone flexibility of a modular tibial revision knee system...
November 29, 2016: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/27831915/effect-of-steroidal-saponins-loaded-nano-bioglass-phosphatidylserine-collagen-bone-substitute-on-bone-healing
#16
Chunrong Yang, Huazhong Wu, Jianhua Wang
The objective of this study was to investigate the therapeutic potential of nano-bioglass/phosphatidylserine/collagen (nBG/PS/COL) scaffolds loaded with steroidal saponins as an inducer factor for skeletal defects. The drugs-encapsulated bone substitute was prepared by loading steroidal saponins-collagen microsphere suspension in nano-bioglass and phosphatidylserine (PS) composite. The scaffolds possess an interconnected porous structure with a porosity of about 82.3%. The pore size ranges from several micrometers up to about 400 μm...
November 10, 2016: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/27770964/strategies-for-delivering-bone-morphogenetic-protein-for-bone-healing
#17
Howa Begam, Samit Kumar Nandi, Biswanath Kundu, Abhijit Chanda
Bone morphogenetic proteins (BMPs) are the most significant growth factors that belong to the Transforming Growth Factor Beta (TGF-β) super-family. Though more than twenty members of this family have been identified so far in humans, Food and Drug Administration (FDA) approved two growth factors: BMP-2 and BMP-7 for treatments of spinal fusion and long-bone fractures with collagen carriers. Currently BMPs are clinically used in spinal fusion, oral and maxillofacial surgery and also in the repair of long bone defects...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27770895/effects-of-halloysite-nanotubes-on-physical-properties-and-cytocompatibility-of-alginate-composite-hydrogels
#18
Biao Huang, Mingxian Liu, Zheru Long, Yan Shen, Changren Zhou
Sodium alginate (SA)/halloysite nanotubes (HNTs) composite hydrogels were successfully prepared by solution blending and cross-linking with calcium ions. HNTs can improve the physical properties and cytocompatibility of composite hydrogels. The static and shear viscosity of SA/HNTs solution increase by the addition of HNTs. FTIR suggests the presence of hydrogen bond interactions between HNTs and SA. The crystal structure of HNTs is retained in the composites as showed by the X-ray diffraction result. A porous structure with pore size of 100-250μm is found in the hydrogels, which can provide a space for cell growth and migration...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27768216/effects-of-various-anchoring-components-and-loading-conditions-on-primary-stability-of-acetabular-revision-implant
#19
Christian Voigt, Andreas Schaller, Carsten Klöhn, Roger Scholz
PURPOSE: In revision total hip arthroplasty, until today, orthopaedic surgeons are missing evidence-based guidelines on cementless acetabular cup fixation. METHODS: 5 finite element models were generated featuring the following anchorage strategies: 1 short peg, 1 long peg, 2 long screws, 3 short screws and zero anchoring components for reference. The micromotions at the implant-bone interface were analyzed for 3 different loadcases, "Seated leg-crossing" (joint force 940 N, impingement force 750 N), "Normal gait" (joint force 1820 N), and "Stumbling" (joint force 4520 N)...
October 15, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27755399/zygomatic-implant-subjected-to-immediate-loading-for-atrophic-maxilla-rehabilitation
#20
Pâmela Letícia Dos Santos, Gustavo Henrique Souza Silva, Fernanda Rayssa Da Silva Pereira, Raquel Damazia da Silva, Mirella Lindoso Gomes Campos, Thiago Borges Mattos, Jéssica Lemos Gulinelli
As life expectancy increases, a larger number of elderly people require dental health care attention for implant-supported rehabilitation, with the aim of restoring the function and aesthetics of the oral cavity. Most of these patients have lost their teeth long time ago, causing a severe bone resorption and maxillary sinus pneumatization. Therefore, the current study aims to demonstrate, through the description of the clinical case, the treatment with zygomatic implants as an option for treating severely atrophic maxillas...
October 14, 2016: Journal of Craniofacial Surgery
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