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https://www.readbyqxmd.com/read/29926955/peri-implant-diseases-and-conditions-consensus-report-of-workgroup-4-of-the-2017-world-workshop-on-the-classification-of-periodontal-and-peri-implant-diseases-and-conditions
#1
Tord Berglundh, Gary Armitage, Mauricio G Araujo, Gustavo Avila-Ortiz, Juan Blanco, Paulo M Camargo, Stephen Chen, David Cochran, Jan Derks, Elena Figuero, Christoph H F Hämmerle, Lisa J A Heitz-Mayfield, Guy Huynh-Ba, Vincent Iacono, Ki-Tae Koo, France Lambert, Laurie McCauley, Marc Quirynen, Stefan Renvert, Giovanni E Salvi, Frank Schwarz, Dennis Tarnow, Cristiano Tomasi, Hom-Lay Wang, Nicola Zitzmann
A classification for peri-implant diseases and conditions was presented. Focused questions on the characteristics of peri-implant health, peri-implant mucositis, peri-implantitis, and soft- and hard-tissue deficiencies were addressed. Peri-implant health is characterized by the absence of erythema, bleeding on probing, swelling, and suppuration. It is not possible to define a range of probing depths compatible with health; Peri-implant health can exist around implants with reduced bone support. The main clinical characteristic of peri-implant mucositis is bleeding on gentle probing...
June 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29926491/peri-implant-diseases-and-conditions-consensus-report-of-workgroup-4-of-the-2017-world-workshop-on-the-classification-of-periodontal-and-peri-implant-diseases-and-conditions
#2
Tord Berglundh, Gary Armitage, Mauricio G Araujo, Gustavo Avila-Ortiz, Juan Blanco, Paulo M Camargo, Stephen Chen, David Cochran, Jan Derks, Elena Figuero, Christoph H F Hämmerle, Lisa J A Heitz-Mayfield, Guy Huynh-Ba, Vincent Iacono, Ki-Tae Koo, France Lambert, Laurie McCauley, Marc Quirynen, Stefan Renvert, Giovanni E Salvi, Frank Schwarz, Dennis Tarnow, Cristiano Tomasi, Hom-Lay Wang, Nicola Zitzmann
A classification for peri-implant diseases and conditions was presented. Focused questions on the characteristics of peri-implant health, peri-implant mucositis, peri-implantitis, and soft- and hard-tissue deficiencies were addressed. Peri-implant health is characterized by the absence of erythema, bleeding on probing, swelling, and suppuration. It is not possible to define a range of probing depths compatible with health; Peri-implant health can exist around implants with reduced bone support. The main clinical characteristic of peri-implant mucositis is bleeding on gentle probing...
June 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29925739/-treatment-of-mandibular-fracture-associated-infectious-pseudarthrosis-accompanied-by-osteomyelitis-in-a-peritoneal-dialysis-patient
#3
Soichi Hirashima, Akihiko Miyawaki, Kotaro Oho, Yawaka Shitozawa, Motohiro Arai, Norihiko Furuta, Ryoichi Oya
Peritoneal dialysis can be performed at home, and the transfer of solutes in the blood and other body fluids is slow compared to hemodialysis, reducing the load on the circulatory organs and lessening the frequency of hospital visits. We encountered a male patient in his 70s on peritoneal dialysis for end-stage renal failure who developed obsolete mandibular fracture-associated pseudarthrosis accompanied by osteomyelitis, which was treated with noninvasive reduction and fixation using circumferential wiring after the resolution of inflammation...
2018: Journal of UOEH
https://www.readbyqxmd.com/read/29922437/a-novel-organ-culture-model-of-a-joint-for-the-evaluation-of-static-and-dynamic-load-on-articular-cartilage
#4
Y-C Lin, A C Hall, A H R W Simpson
Objectives: The purpose of this study was to create a novel ex vivo organ culture model for evaluating the effects of static and dynamic load on cartilage. Methods: The metatarsophalangeal joints of 12 fresh cadaveric bovine feet were skinned and dissected aseptically, and cultured for up to four weeks. Dynamic movement was applied using a custom-made machine on six joints, with the others cultured under static conditions. Chondrocyte viability and matrix glycosaminoglycan (GAG) content were evaluated by the cell viability probes, 5-chloromethylfluorescein diacetate (CMFDA) and propidium iodide (PI), and dimethylmethylene blue (DMMB) assay, respectively...
March 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29909943/onlay-grafting-with-bovine-bone-mineral-block-for-horizontal-reconstruction-of-severely-atrophic-alveolar-ridges-in-anterior-maxillae-a-6-year-prospective-study
#5
Lixin Qiu, Huajie Yu
PURPOSE: The aim of this prospective study was to evaluate the efficacy and long-term outcomes of onlay grafting with bovine bone mineral block for reconstruction of horizontal alveolar ridge defects in anterior maxillae. MATERIALS AND METHODS: Fourteen patients requiring rehabilitation of edentulous anterior maxillae were enrolled to receive onlay grafting in two layers. A cortical block harvested from the lateral aspect of the mandibular ramus was split to acquire approximately 1-mm-thick bone laminae...
April 18, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29890922/controlled-release-of-celecoxib-inhibits-inflammation-bone-cysts-and-osteophyte-formation-in-a-preclinical-model-of-osteoarthritis
#6
A R Tellegen, I Rudnik-Jansen, B Pouran, H M de Visser, H H Weinans, R E Thomas, M J L Kik, G C M Grinwis, J C Thies, N Woike, G Mihov, P J Emans, B P Meij, L B Creemers, M A Tryfonidou
Major hallmarks of osteoarthritis (OA) are cartilage degeneration, inflammation and osteophyte formation. COX-2 inhibitors counteract inflammation-related pain, but their prolonged oral use entails the risk for side effects. Local and prolonged administration in biocompatible and degradable drug delivery biomaterials could offer an efficient and safe treatment for the long-term management of OA symptoms. Therefore, we evaluated the disease-modifying effects and the optimal dose of polyesteramide microspheres delivering the COX-2 inhibitor celecoxib in a rat OA model...
November 2018: Drug Delivery
https://www.readbyqxmd.com/read/29871018/management-of-hcv-related-liver-disease-in-hemophilia-and-thalassemia
#7
Maria Grazia Rumi, Vito Di Marco, Massimo Colombo
Chronic infection with the hepatitis C virus (HCV) has long been the dominant complication of substitution therapy in patients with inherited blood disorders and the cause of anticipated death due to end-stage liver disease. In hemophilia, transmission of HCV with clotting factors concentrates started to be curbed in the mid-1980s following the adoption of procedures of virus inactivation of concentrates based on heat, whereas in the 1990s treatment of HCV infection with interferon monotherapy was attempted, however, with little success...
May 2018: Seminars in Liver Disease
https://www.readbyqxmd.com/read/29858707/a-nonlinear-homogenized-finite-element-analysis-of-the-primary-stability-of-the-bone-implant-interface
#8
Marzieh Ovesy, Benjamin Voumard, Philippe Zysset
Stability of an implant is defined by its ability to undergo physiological loading-unloading cycles without showing excessive tissue damage and micromotions at the interface. Distinction is usually made between the immediate primary stability and the long-term, secondary stability resulting from the biological healing process. The aim of this research is to numerically investigate the effect of initial implantation press-fit, bone yielding, densification and friction at the interface on the primary stability of a simple bone-implant system subjected to loading-unloading cycles...
June 1, 2018: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29857955/a-review-of-bone-metabolism-and-developments-in-medical-treatment-of-the-diabetic-charcot-foot
#9
REVIEW
Rasmus Bo Jansen, Ole Lander Svendsen
Charcot foot is a rare but severe, and possibly limb-threatening, complication to neuropathy and diabetes mellitus. The current treatment consists of long-term off-loading, and has a large negative impact on the patient's life. Much research has gone into understanding the condition and its biochemical mechanisms, however, the underlying pathogenesis of a Charcot foot is not yet fully understood. In the recent decades several key advances in our understanding of the Charcot foot have been made, both in regards to the changes in bone metabolism and structure an acute Charcot foot can cause, and to the molecular pathways involved in this...
April 27, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29850002/effect-of-constraint-loading-on-the-lower-limb-muscle-forces-in-weightless-treadmill-exercise
#10
Ning Guo, Xingyu Fan, Yuting Wu, Zhili Li, Shujuan Liu, Linjie Wang, Jie Yao, Yinghui Li
Long exposure to the microgravity will lead to muscle atrophy and bone loss. Treadmill exercise could mitigate the musculoskeletal decline. But muscle atrophy remains inevitable. The constraint loading applied on astronauts could affect the muscle force and its atrophy severity. However, the quantitative correlation between constraint loading mode and muscle forces remains unclear. This study aimed to characterize the influence of constraint loading mode on the lower limb muscle forces in weightless treadmill exercise...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29813182/long-term-and-recent-weight-change-are-associated-with-reduced-peripheral-bone-density-deficits-in-bone-microarchitecture-and-decreased-bone-strength-the-framingham-osteoporosis-study
#11
Ching-Ti Liu, Shivani Sahni, Hanfei Xu, Robert R McLean, Kerry E Broe, Marian T Hannan, Steven K Boyd, Mary L Bouxsein, Douglas P Kiel, Elizabeth J Samelson
BACKGROUND: Weight loss in older adults is associated with increased bone loss and fracture. Little is known about the potential impact of weight loss on cortical and trabecular bone density, microarchitecture, and strength. METHODS: Participants were members of the Framingham Offspring Cohort (769 women, 595 men; mean age 70× ± 8 years), who underwent high-resolution peripheral quantitative computed tomography (HR-pQCT) scanning at the tibia and radius in 2012-2016...
May 29, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29806665/posterior-atrophic-jaws-rehabilitated-with-prostheses-supported-by-6-mm-long-%C3%A3-4-mm-wide-implants-or-by-longer-implants-in-augmented-bone-3-year-post-loading-results-from-a-randomised-controlled-trial
#12
Pietro Felice, Carlo Barausse, Valeria Pistilli, Maurizio Piattelli, Daniela Rita Ippolito, Marco Esposito
PURPOSE: To evaluate whether 6 mm long × 4 mm wide dental implants could be an alternative to implants of at least 10 mm long placed in bone augmented with bone substitutes in posterior atrophic jaws. MATERIALS AND METHODS: A total of 20 patients with bilateral atrophic mandibles, and 20 patients with bilateral atrophic maxillae, having 5 mm to 7 mm of bone height below the maxillary sinus or 6 mm to 8 mm above the mandibular canal, had their side of the jaws randomly allocated according to a split-mouth design...
2018: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/29806663/immediately-loaded-zygomatic-implants-vs-conventional-dental-implants-in-augmented-atrophic-maxillae-1-year-post-loading-results-from-a-multicentre-randomised-controlled-trial
#13
Rubén Davó, Pietro Felice, Roberto Pistilli, Carlo Barausse, Carlos Marti-Pages, Ada Ferrer-Fuertes, Daniela Rita Ippolito, Marco Esposito
PURPOSE: To compare the clinical outcome of immediately loaded cross-arch maxillary prostheses supported by zygomatic implants vs conventional implants placed in augmented bone. MATERIALS AND METHODS: In total, 71 edentulous patients with severely atrophic maxillas without sufficient bone volumes for placing dental implants, or when it was possible to place only two implants in the anterior area (minimal diameter 3.5 mm and length of 8 mm) and less than 4 mm of bone height subantrally, were randomised according to a parallel group design to receive zygomatic implants (35 patients) to be loaded immediately vs grafting with a xenograft, followed after 6 months of graft consolidation by placement of six to eight conventional dental implants submerged for 4 months (36 patients)...
2018: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/29802060/impact-of-different-placement-depths-on-the-crestal-bone-level-of-immediate-versus-delayed-placed-platform-switched-implants
#14
Elika Madani, Ralf Smeets, Eric Freiwald, Maryam Setareh Sanj, Ole Jung, Daniel Grubeanu, Henning Hanken, Anders Henningsen
PURPOSE: The preservation of peri-implant bone is one requirement for long-term success of dental implants. The purpose of this study was to evaluate the impact of subcrestal placement on the crestal bone level of immediate versus delayed placed implants after loading. MATERIALS AND METHODS: In this retrospective study, data of 159 patients who received 330 implants was analyzed. Implants were placed subcrestally, crestally or supracrestally into fresh sockets or healed sites...
May 9, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29798583/-effectiveness-analysis-of-ilizarov-external-fixation-and-ankle-arthrodesis-in-treatment-of-late-traumatic-ankle-arthritis
#15
Jun Li, Zeyu Huang, Yue Fang, Fuguo Huang, Lei Liu
Objective: To evaluate the effectiveness of Ilizarov external fixation and ankle arthrodesis in the treatment of late traumatic ankle arthritis. Methods: Between June 2013 and June 2015, 27 patients with late traumatic ankle arthritis were treated with Ilizarov external fixation technique. There were 16 males and 11 females with an age of 27-69 years (mean, 45.7 years). Sixteen cases were on the left side, 11 on the right side. All the patients suffered from traumatic ankle fractures or ligament damages caused by initial traumas...
November 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29787632/peri-implant-soft-tissue-status-and-crestal-bone-levels-around-adjacent-implants-placed-in-patients-with-and-without-type-2-diabetes-mellitus-6-years-follow-up-results
#16
Mohammed N Alasqah, Mohammed Alrabiah, Khulud Abdulrahman Al-Aali, Sameer A Mokeem, Abdulelah M Binmahfooz, Aws S ArRejaie, Tariq Abduljabbar
BACKGROUND: The long-term success and survival of dental implants type-2 diabetic subjects is debatable. PURPOSE: The present 6 years' follow-up prospective clinical study compared the peri-implant soft tissue status and crestal bone loss (CBL) around adjacent implants placed among type-2 diabetic and nondiabetic subjects. MATERIALS AND METHODS: Type-2 diabetic (Group-1) and nondiabetic individuals (Group-2) with adjacent dental implants were included...
May 22, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29785178/functionally-graded-bone-and-tendon-like-polyurethane-for-rotator-cuff-repair
#17
Dai Fei Elmer Ker, Dan Wang, Anthony William Behn, Evelyna Tsi Hsin Wang, Xu Zhang, Benjamin Yamin Zhou, Ángel Enrique Mercado-Pagán, Sungwoo Kim, John Kleimeyer, Burhan Gharaibeh, Yaser Shanjani, Drew Nelson, Marc Safran, Emilie Cheung, Phil Campbell, Yunzhi Peter Yang
Critical considerations in engineering biomaterials for rotator cuff repair include bone-tendon-like mechanical properties to support physiological loading and biophysicochemical attributes that stabilize the repair site over the long-term. In this study, UV-crosslinkable polyurethane based on quadrol (Q), hexamethylene diisocyante (H), and methacrylic anhydride (M; QHM polymers), which are free of solvent, catalyst, and photoinitiator, is developed. Mechanical characterization studies demonstrate that QHM polymers possesses phototunable bone- and tendon-like tensile and compressive properties (12-74 MPa tensile strength, 0...
May 2018: Advanced Functional Materials
https://www.readbyqxmd.com/read/29774956/cement-interface-and-bone-stress-in-total-hip-arthroplasty-relationship-to-head-size
#18
Teresa Alonso-Rasgado, Jose F Del-Valle-Mojica, David Jimenez-Cruz, Colin G Bailey, Tim N Board
The use of larger prosthetic femoral heads in total hip arthroplasty (THA) has increased considerably in recent years in response to the need to improve joint stability and reduce risk of dislocation. However, data suggests larger femoral heads are associated with higher joint failure rates. For cemented implants, ensuring the continued integrity of the cement mantle is key to long term fixation. This paper describes an investigation into the effect of variation in femoral head size on stresses in the acetabular cement mantle and pelvic bone...
May 18, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29772348/biosafety-stability-and-osteogenic-activity-of-novel-implants-made-of-zr-70-ni-16-cu-6-al-8-bulk-metallic-glass-for-biomedical-application
#19
Hiroto Ida, Masahiro Seiryu, Nobuo Takeshita, Masanari Iwasaki, Yoshihiko Yokoyama, Yusuke Tsutsumi, Etsuko Ikeda, Satoshi Sasaki, Shunro Miyashita, Shutaro Sasaki, Tomohiro Fukunaga, Toru Deguchi, Teruko Takano-Yamamoto
Superior mechanical and chemical properties of Zr70 Ni16 Cu6 Al8 bulk metallic glass (BMG) demonstrate its promise as a novel biomaterial for fabrication of implants. The aim of the present study was to validate mechanical, chemical, and biological properties of Zr70 Ni16 Cu6 Al8 BMG through comparison with titanium (Ti). Our data indicated higher tensile strength, lower Young's modulus, and reduced metal ion release of Zr70 Ni16 Cu6 Al8 BMG compared with Ti. Biosafety of bone marrow mesenchymal cells on Zr70 Ni16 Cu6 Al8 BMG was comparable to that of Ti...
May 14, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29761979/-remodeling-simulation-of-human-femur-under-bed-rest-and-spaceflight-circumstances-based-on-three-dimensional-finite-element-analysis
#20
Wenting Yang, Dongmei Wang, Zhoujixin Lei, Chunhui Wang, Shanguang Chen
Astronauts who are exposed to weightless environment in long-term spaceflight might encounter bone density and mass loss for the mechanical stimulus is smaller than normal value. This study built a three dimensional model of human femur to simulate the remodeling process of human femur during bed rest experiment based on finite element analysis (FEA). The remodeling parameters of this finite element model was validated after comparing experimental and numerical results. Then, the remodeling process of human femur in weightless environment was simulated, and the remodeling function of time was derived...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
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