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https://www.readbyqxmd.com/read/29457499/factors-related-to-alcohol-consumption-among-japanese-physicians
#1
Noriyasu Ohida, Yuichiro Otsuka, Yoshitaka Kaneita, Sachi Nakagome, Maki Jike, Osamu Itani, Takashi Ohida
This study aimed to investigate the drinking habits of Japanese physicians, and clarify their causal factors. A self-administered questionnaire was sent to 6000 male and 1500 female physicians, selected from among members of the Japan Medical Association. We analyzed the correlation of drinking habits with age, medical department, smoking and exercise status, work environment, sleep problems, and mental health. The response rate was 79.4%. Physicians with a heavy drinking habit were most frequently men in their 60s and women in their 20s to 50s...
February 1, 2018: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/29457361/cognitive-function-and-unsafe-driving-acts-during-an-on-road-test-among-community-dwelling-older-adults-with-cognitive-impairments
#2
Ryo Hotta, Hyuma Makizako, Takehiko Doi, Kota Tsutsumimoto, Sho Nakakubo, Keitaro Makino, Hiroyuki Shimada
AIM: To examine the relationship between cognitive function and unsafe driving acts among community-dwelling older adults with cognitive impairments. METHODS: Participants (n = 160) were older residents of Obu, Japan, aged ≥65 years with cognitive impairments. They regularly drove and were assessed for the number of unsafe driving acts without adequate verification during an on-road test. We also evaluated cognitive function (attention, executive function and processing speed)...
February 19, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29457111/mortality-and-physical-status-at-hospital-discharge-in-japanese-elderly-critically-ill-patients-a-single-center-retrospective-study
#3
Tomoaki Yatabe, Atsushi Nishigaki, Takahiko Tamura, Masataka Yokoyama
Background: Because there is ongoing population aging, the age of patients admitted to the intensive care unit (ICU) is also higher. However, the evidence about outcomes in elderly patients is insufficient in Japan. Therefore, we conducted a retrospective study. Method: The study participants were consecutive patients who were admitted to our ICU and received mechanical ventilation for more than 24 h. We divided the patients into two groups, according to age. Patients in group A were 74 years old or younger, and those in group B were 75 years old or older...
2018: JA Clin Rep
https://www.readbyqxmd.com/read/29456777/toe-gap-force-is-related-to-ultrasonic-parameter-of-calcaneus-bone-status-in-general-population
#4
Tsuyoshi Tajika, Atsushi Yamamoto, Noboru Oya, Takanori Kitagawa, Hiroki Kobayashi, Hitoshi Shitara, Haku Iizuka, Kenji Takagishi, Hirotaka Chikuda
Background: Elucidating the relation between bone health condition and muscle strength can provide useful knowledge for Japan's super-aged society. This study ascertained the Speed Of Sound (SOS) of the calcaneus and upper and lower limb muscle strength in a general population. Methods: Medical examinations were conducted of 277 adult residents (100 men, 177 women; average age 67.1 years) of a mountain village. Bilateral hand grip and hand key pinch strength were measured...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29456729/expression-of-matrix-metalloproteinase-7-correlates-with-the-invasion-of-t1-colorectal-carcinoma
#5
Fumihiko Urushibara, Eisuke Shiozawa, Hideyuki Miyachi, Masashi Misawa, Tomonari Cho, Yusuke Takehara, Nana Arai, Toshitaka Funaki, Sakiko Tazawa, Mayumi Homma, Tomoko Norose, Mutsuko Omatsu, Toshiko Yamochi, Toshiaki Kunimura, Genshu Tate, Kazuho Honda, Ishida Fumio, Shin-Ei Kudo, Masafumi Takimoto
T1 colorectal carcinomas (CRCs) are an initial site of metastatic spread. Various risk factors for lymph node metastasis have been investigated in T1 CRCs. However, the major step in the entire process of metastasis remains unclear. In terms of carcinoma invasion and metastasis, matrix metalloproteinases (MMPs) have recently gained increasing attention. Notably, MMP-7 is frequently overexpressed in CRCs, but its implication has not been determined in T1 CRCs yet. The present study aimed to clarify the associations between the pathological risk factors of T1 CRCs and MMP-7...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29456643/multiple-brain-abscesses-caused-by-infection-with-candida-glabrata-a-case-report
#6
Zifeng Zhu, Zhehao Huang, Zhenshengnan Li, Xianglan Li, Chao Du, Yu Tian
The present case report described the initial diagnosis of a 25-year old female with a brain abscess consisting of two lesions 0.2 and 2.9 cm3 in volume. The patient was initially treated with antibiotics; however, 2 months following initial treatment, the patient's condition deteriorated and she became vegetative. Following transfer to the China-Japan Union Hospital of Jilin University (Jilin, China) the two lesions had grown in volume to 9.0 and 13.0 cm3 , respectively. The results of magnetic resonance spectroscopy and plasma 1-3-β-D-glucan activity suggested a possible fungal infection...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456275/antimicrobial-packaging-based-on-%C3%A9-polylysine-bioactive-film-for-the-control-of-mycotoxigenic-fungi-in-vitro-and-in-bread
#7
C Luz, J Calpe, F Saladino, Fernando B Luciano, M Fernandez-Franzón, J Mañes, G Meca
ɛ-Poly-l-lysine (ɛ-PL) is a cationic peptide with a broad-spectrum antimicrobial activity. This study investigates the use of ɛ-PL as natural antimicrobial to inhibit fungal growth and to reduce aflatoxins (AFs) production. Antifungal activity of starch biofilms with different concentrations of ɛ-Poly-l-lysine (ɛ-PL) was determined in solid medium against Aspergillus parasiticus (AFs producer) and Penicillium expansum . Then, biofilms were tested as antimicrobial devices for the preservation of bread loaf inoculated with A...
January 2018: Journal of Food Processing and Preservation
https://www.readbyqxmd.com/read/29455796/percutaneous-transradial-artery-approach-for-femoro-popliteal-artery-intervention-in-the-current-era-in-japan
#8
Akihiro Nakamura, Masanori Kanazawa, Kazuki Noda, Hideaki Endo, Tohru Takahashi, Eiji Nozaki
The percutaneous transradial artery approach for coronary angiography and intervention has been recognized as a safe and effective method, however, it is limited for endovascular therapy (EVT) for femoro-popliteal artery because of lack of devices with longer shaft. Herein, we report two EVT cases for superficial femoral artery disease treated with a long shaft balloon through the radial artery. Although femoro-popliteal artery intervention with this approach has several limits for available devices and technical issues, it is effective for particular patients who are impossible in EVT with femoral artery approach...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29455699/existing-approaches-to-chemical-biological-radiological-and-nuclear-cbrn-education-and-training-for-health-professionals-findings-from-an-integrative-literature-review
#9
Mayumi Kako, Karen Hammad, Satoko Mitani, Paul Arbon
OBJECTIVES: This review was conducted to explore the literature to determine the availability, content, and evaluation of existing chemical, biological, radiological, and nuclear (CBRN) education programs for health professionals. METHODS: An integrative review of the international literature describing disaster education for CBRN (2004-2016) was conducted. The following relevant databases were searched: Proquest, Pubmed, Science Direct, Scopus, Journals @ OVID, Google Scholar, Medline, and Ichuschi ver...
February 19, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29455380/clinical-features-and-peripartum-outcomes-in-pregnant-women-with-cardiac-disease-a-nationwide-retrospective-cohort-study-in-japan
#10
Toshiaki Isogai, Hiroki Matsui, Hiroyuki Tanaka, Akira Kohyama, Kiyohide Fushimi, Hideo Yasunaga
Although the number of pregnancies in women with cardiac disease is increasing worldwide, there are few data concerning their clinical characteristics and peripartum outcomes. Using the Diagnosis Procedure Combination database between 2008 and 2014 in Japan, we retrospectively identified pregnant women who underwent high-risk delivery due to obstetric or non-obstetric comorbidities. We classified eligible women into those with pre-existing cardiac disease (cardiac disease group) and those with non-cardiac comorbidities (non-cardiac disease group) and compared their characteristics and peripartum outcomes...
February 17, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29455197/incidence-and-characteristics-of-adrenal-crisis-in-children-younger-than-7-years-with-21-hydroxylase-deficiency-a-nationwide-survey-in-japan
#11
Tomohiro Ishii, Masanori Adachi, Kei Takasawa, Satoshi Okada, Hotaka Kamasaki, Takuo Kubota, Hironori Kobayashi, Hirotake Sawada, Keisuke Nagasaki, Chikahiko Numakura, Shohei Harada, Kanshi Minamitani, Shigetaka Sugihara, Toshihiro Tajima
BACKGROUND/AIMS: We aimed to evaluate the incidence and characteristics of adrenal crisis in Japanese children with 21-hydroxylase deficiency (21-OHD). METHODS: We conducted a retrospective nationwide survey for the councilors of the Japanese Society for Pediatric Endocrinology (JSPE) regarding adrenal crisis in children under 7 years with 21-OHD, admitted to hospitals from 2011 through 2016. We defined adrenal crisis as the acute impairment of general health due to glucocorticoid deficiency with at least two of symptoms, signs, or biochemical abnormalities...
February 16, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29455058/physical-activity-combined-with-resistance-training-reduces-symptoms-of-frailty-in-older-adults-a-randomized-controlled-trial
#12
Koutatsu Nagaia, Toshiaki Miyamato, Akio Okamae, Akira Tamaki, Hiroyuki Fujioka, Yosuke Wada, Yuki Uchiyama, Ken Shinmura, Kazuhisa Domen
INTRODUCTION: Increased physical activity (PA) is a crucial factor in the prevention of physical deterioration, and resistance training (RT) is also a common and effective intervention for older adults. However, the effects of PA as an adjunct to RT on frailty status remains unclear; therefore, we clarified the effect of a PA intervention with feedback, as an adjunct to resistance strength training, on the physical and mental outcomes of frail older adults. MATERIALS AND METHODS: We employed a randomized controlled trial...
February 13, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29454980/cumulative-incidence-of-suicidal-ideation-and-associated-factors-among-adults-living-in-temporary-housing-during-the-three-years-after-the-great-east-japan-earthquake
#13
Qingyi Xu, Maiko Fukasawa, Norito Kawakami, Toshiaki Baba, Kiyomi Sakata, Ruriko Suzuki, Hiroaki Tomita, Harumi Nemoto, Seiji Yasumura, Hirooki Yabe, Naoko Horikoshi, Maki Umeda, Yuriko Suzuki, Haruki Shimoda, Hisateru Tachimori, Tadashi Takeshima, Evelyn J Bromet
BACKGROUND: The effect of disasters on suicidality is not known. We aimed to retrospectively determine the cumulative incidence of suicidal ideation during the 3 years after the Great East Japan Earthquake among residents in temporary housing without prior suicidal ideation, as compared to the general population. Moreover, we aimed to identify the risk factors for the onset of suicidal ideation. METHODS: A cross-sectional survey involving face-to-face interviews was conducted 3 years after the earthquake with adult community residents in disaster-affected areas and a control area using the World Health Organization Composite International Diagnostic Interview version 3...
February 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29454850/dissemination-of-panton-valentine-leukocidin-positive-methicillin-resistant-staphylococcus-aureus-usa300-clone-in-multiple-hospitals-in-tokyo-japan
#14
Shunsuke Takadama, Hidemasa Nakaminami, Asami Sato, Manami Shoshi, Takeshi Fujii, Norihisa Noguchi
OBJECTIVE: Panton-Valentine leukocidin (PVL) gene (lukS/F-PV)-positive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), particularly the USA300 clone, is a health concern worldwide. Recently, CA-MRSA clones have been found to spread and persist in hospital settings. In this study, we aimed to investigate the prevalence and molecular epidemiological features of lukS/F-PV-positive MRSA in Japanese hospitals. METHODS: A total of 3,433 MRSA isolated from nine hospitals in 2011-2015 were used...
February 15, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29454051/retrospective-observational-study-of-the-use-of-artemether-lumefantrine-in-the-treatment-of-malaria-in-japan
#15
Fukumi Nakamura-Uchiyama, Yuichi Katanami, Tadashi Kikuchi, Saho Takaya, Satoshi Kutsuna, Taiichiro Kobayashi, Yasutaka Mizuno, Tetsuo Hasegawa, Michiko Koga, Yukihiro Yoshimura, Chihiro Hasegawa, Yasuyuki Kato, Mikio Kimura, Haruhiko Maruyama
BACKGROUND: The Research Group on Chemotherapy of Tropical Diseases, Japan, introduced artemether-lumefantrine (AL) in late 2002, mainly for treating uncomplicated Plasmodium falciparum malaria. Because AL was on the market in Japan in March 2017, the effectiveness and safety of AL were analyzed to help medical personnel use AL optimally. METHODS: Case report forms submitted by the attending physicians were analyzed. When necessary, direct contact with the attending physicians was made to obtain detailed information...
February 14, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29453793/cross-cultural-comparison-of-predictors-for-self-care-behaviors-in-patients-with-type-2-diabetes
#16
Kaori Ikeda, Shimpei Fujimoto, Beth Morling, Shiho Ayano-Takahara, Shin-Ichi Harashima, Yukiko Uchida, Nobuya Inagaki
The aim of this study is to evaluate how culture moderates the behavioral and psychosocial predictors of diabetes self-care activities. Patients with type 2 diabetes were recruited in the outpatient department at two sites: Kyoto University hospital in Japan and the Christiana Care Health System in the United States. The data was collected by survey using questionnaires including questions on the frequency of self-care activities, behavioral and psychosocial predictors, and other background information from 149 Japanese patients and 48 American patients...
February 17, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29453774/hobnail-retiform-dabska-hemangioendothelioma-located-in-jejunum
#17
Yuxin Wang, Huan Han, Yiqi Du
A 27-year-old man referred to our department with a 1-month history of intermittent melena and dizziness. Gastroscopy and colonoscopy did not identify the site of bleeding. Laboratory data showed hemoglobin 6.6g/dL. Video capsule endoscopy (CE, Anhon,China) and antegrade double-ballon enteroscopy (DBE, EN450P5, Fujinon, Japan) were carried out and a space occupying lesion in the proximal jejunum was identified (Fig.1). Ink tattooing via DBE was performed to mark the site of the tumor.Then the patient underwent jejunectomy...
February 17, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29453668/netarsudil-ophthalmic-solution-0-02-first-global-approval
#18
Sheridan M Hoy
Netarsudil ophthalmic solution 0.02% (hereafter referred to as netarsudil 0.02%) [Rhopressa ® ] is a Rho-associated protein kinase inhibitor that is thought to lower intraocular pressure (IOP) by increasing aqueous humour outflow through the trabecular meshwork. It has been developed by Aerie Pharmaceuticals and was recently approved in the USA for the reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension. The recommended dosage is one drop in the affected eye(s) once daily in the evening...
February 16, 2018: Drugs
https://www.readbyqxmd.com/read/29453512/global-and-japanese-regional-variations-in-radiologist-potential-workload-for-computed-tomography-and-magnetic-resonance-imaging-examinations
#19
Kanako K Kumamaru, Akihiro Machitori, Ritsuko Koba, Shinpei Ijichi, Yasuo Nakajima, Shigeki Aoki
PURPOSE: To investigate the global variation in radiologist potential workload for CT and MRI examinations, and the regional variation in potential workload and extent of radiologists' involvement in CT and MRI examinations in Japan. METHODS: "Radiologist potential workload" was defined as the annual number of CT plus MRI examinations divided by the total number of diagnostic radiologists. The extent of radiologists' involvement was measured as the proportion of CT and MRI examinations to which "Added-fees for Radiological Managements on Imaging-studies (ARMIs)" were applied among eligible examinations...
February 16, 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29453335/high-definition-and-low-noise-muography-of-the-sakurajima-volcano-with-gaseous-tracking-detectors
#20
László Oláh, Hiroyuki K M Tanaka, Takao Ohminato, Dezső Varga
Muography is a novel method to highly resolve the internal structure of active volcanoes by taking advantage of the cosmic muon's strong penetration power. In this paper, we present the first high-definition image in the vicinity of craters of an erupting volcano called Sakurajima, Kyushu, Japan. The muography observation system based on the technique of multi-wire proportional chamber (mMOS) has been operated reliably during the data taking period of 157 days. The mMOS measured precisely the flux of muons up to the thickness of 5,000 meter-water-equivalent...
February 16, 2018: Scientific Reports
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