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https://www.readbyqxmd.com/read/28817556/risk-behaviors-for-contact-lens-related-eye-infections-among-adults-and-adolescents-united-states-2016
#1
Jennifer R Cope, Sarah A Collier, Hannah Nethercut, Jefferson M Jones, Kirsten Yates, Jonathan S Yoder
Contact lens-related eye infections, which can lead to serious outcomes, including blindness, are associated with several risk factors, including sleeping in lenses, exposing lenses to water, not adhering to replacement schedules, and reusing disinfecting solution (1). In some studies, adolescent and young adult contact lens wearers have been reported to be more likely than older adult contact lens wearers to develop eye infections (2,3) and more likely to have poor contact lens hygiene practices (2). In 2015, CDC reported the number and demographics of adult contact lens wearers in the United States to define the population at risk for contact lens-related eye infections (4); however, this estimate did not include adolescents...
August 18, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28817554/occupational-distribution-of-campylobacteriosis-and-salmonellosis-cases-maryland-ohio-and-virginia-2014
#2
Chia-Ping Su, Marie A de Perio, Kathleen Fagan, Meghan L Smith, Ellen Salehi, Seth Levine, Karen Gruszynski, Sara E Luckhaupt
Campylobacter and Salmonella are leading causes of bacterial gastroenteritis in the United States and are estimated to cause >1 million episodes of domestically acquired illness annually (1). Campylobacter and Salmonella are primarily transmitted through contaminated food, but animal-to-human and human-to-human transmission can also occur (2,3). Although occupationally acquired infections have been reported, occupational risk factors have rarely been studied. In 2015, the Occupational Safety and Health Administration (OSHA) identified 63 suspected or confirmed cases of Campylobacter infection over 3...
August 18, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28817308/a-2017-update-centers-for-disease-control-and-prevention-s-contributions-and-investments-in-breastfeeding
#3
Ruth Petersen
Given that breastfeeding is important to the health of infants and their mothers, the Centers for Disease Control and Prevention's (CDC) goal is to ensure that new mothers understand the benefits of breastfeeding and, when they choose to breastfeed, have the supports they need to successfully initiate and continue breastfeeding until they reach their goals. This report summarizes CDC's current contributions and investments in breastfeeding.
August 17, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28815634/effect-of-trapping-methods-on-the-estimation-of-alpha-diversity-of-a-phlebotomine-sandfly-assemblage-in-southern-mexico
#4
J J Rodríguez-Rojas, E A Rebollar-Téllez
The aims of the study were to (a) investigate the effect of trapping methods on alpha diversity; and (b) enhance the knowledge of the sandfly assemblage in the state of Quintana Roo. Field work was undertaken in a tropical forest of southern Mexico from August 2013 to July 2014. Sampling was conducted monthly during three consecutive nights. For each trapping night, 12 different types of trap were operated from 18.00 to 24.00 hours in four transects. Measures of alpha community diversity were based on the quantification of the number of species (Chao 2, Jackknife 2, Clench's equation, Margalef's index) and the community structure, as well as the dominance (Simpson and Berger-Parker indexes) and evenness (Shannon's entropy index, true diversity of the Jost and Pielou index)...
August 17, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28814955/characterization-of-carbapenem-resistant-acinetobacter-baumannii-strains-isolated-from-hospitalized-patients-in-palestine
#5
Regeen Handal, Lulu Qunibi, Ibrahim Sahouri, Maha Juhari, Rula Dawodi, Hiyam Marzouqa, Musa Hindiyeh
The American Centers for Disease Control and Prevention (CDC) recognizes Acinetobacter baumannii as a source of global outbreaks and epidemics especially due to its increasing resistance to commercially available antibiotics. In this study, 69 single patient multidrug resistant isolates collected from all over Palestine, except Gaza, were studied. All the isolates were resistant to all the β-lactam antibiotics including the carbapenems. Of the 69 isolates, 82.6% were positive for blaOXA-23, 14.5% were positive for blaOXA-24, and 3% were positive for blaOXA-58...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28814737/susceptibility-of-influenza-a-h1n1-pdm2009-seasonal-a-h3n2-and-b-viruses-to-oseltamivir-in-guangdong-china-between-2009-and-2014
#6
Shan-Shan Liu, Xiao-Yang Jiao, Sheng Wang, Wen-Zhe Su, Ling-Zhi Jiang, Xin Zhang, Chang-Wen Ke, Ping Xiong
Nasopharyngeal swabs were collected from patients through the influenza surveillance network of the CDC of Guangdong. All specimens between 2009 and 2014 were checked for influenza virus using MDCK cells and further subtyped. Of those collected, 542 H1N1pdm09, 230 A(H3N2)and 448 B viruses selected at random were subjected to fluorescence-based NAI assays. Viral RNA was extracted from resistant isolates, and their NA genes were amplified by RT-PCR. Alignment of nucleotides and amino acids was performed. We performed structural modelling and simulations of mutants using Modeller 9...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814536/the-future-of-fragile-x-syndrome-cdc-stakeholder-meeting-summary
#7
Catharine Riley, Marsha Mailick, Elizabeth Berry-Kravis, Julie Bolen
No abstract text is available yet for this article.
June 2017: Pediatrics
https://www.readbyqxmd.com/read/28813400/africa-s-cdc-can-end-malaria
#8
Carl Manlan
No abstract text is available yet for this article.
August 15, 2017: Scientific American
https://www.readbyqxmd.com/read/28811679/bisphenol-a-does-not-mimic-estrogen-in-the-promotion-of-the-in-vitro-response-of-murine-dendritic-cells-to-toll-like-receptor-ligands
#9
Marita Chakhtoura, Uma Sriram, Michelle Heayn, Joshua Wonsidler, Christopher Doyle, Joudy-Ann Dinnall, Stefania Gallucci, Rebecca A Roberts
Sex hormones affect immune responses and might promote autoimmunity. Endocrine disrupting chemicals such as bisphenol A (BPA) may mimic their immune effects. Conventional dendritic cells (cDCs) are pivotal initiators of immune responses upon activation by danger signals coming from pathogens or distressed tissues through triggering of the Toll-like receptors (TLRs). We generated in vitro murine cDCs in the absence of estrogens and measured the effects of exogenously added estrogen or BPA on their differentiation and activation by the TLR ligands LPS and CpG...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28810872/-repel-all-biters-an-enhanced-collection-of-endophilic-anopheles-gambiae-and-anopheles-arabiensis-in-cdc-light-traps-from-the-kagera-region-of-tanzania-in-the-presence-of-a-combination-mosquito-net-impregnated-with-piperonyl-butoxide-and-permethrin
#10
Corey LeClair, Judith Cronery, Enock Kessy, Elsa V E Tomás, Yohannes Kulwa, Franklin W Mosha, Mark Rowland, Natacha Protopopoff, J Derek Charlwood
BACKGROUND: Mosquito nets containing synergists designed to overcome metabolic resistance mechanisms in vectors have been developed. These may enhance excitability in the mosquitoes and affect how they respond to CDC light-traps. Investigating the behaviour of vectors of disease in relation to novel mosquito nets is, therefore, essential for the design of sampling and surveillance systems. METHODS: In an initial experiment in Muleba, Tanzania, nine bedrooms from three housing clusters were sampled...
August 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28810813/newborn-thyroid-screening-influence-of-pre-analytic-variables-on-dried-blood-spot-tsh-measurement
#11
Allison M Butler, Wiyada Charoensiriwatana, Piamnukul Krasao, Rotjanapan Pankanjanato, Penpan Thong-Ngao, Randall C Polson, Gregory L Snow, Joel Ehrenkranz
BACKGROUND: Measuring thyroid stimulating hormone (TSH) eluted from a dried blood spot (DBS) is used to screen an estimated 30 million newborns annually for congenital hypothyroidism. Newborn thyroid screening has eliminated cretinism from the industrialized world and decreased the adverse effects of unrecognized congenital hypothyroidism on neurocognitive development. Hematocrit, a pre-analytic variable that affects the measurement of TSH from a DBS, contributes to the imprecision of DBS TSH measurement and could account for false negative and false positive DBS newborn screening test results...
August 16, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28808612/para-i-famagu-on-ta-fruit-and-vegetable-intake-food-store-environment-and-childhood-overweight-obesity-in-the-children-s-healthy-living-program-on-guam
#12
Lenora Matanane, Marie Kainoa Fialkowski, Joshua Silva, Fenfang Li, Claudio Nigg, Rachael T Leon Guerrero, Rachel Novotny
This cross-sectional study examined the: (1) association between food store environment (FSE), fruit and vegetable (FV) availability and access, and prevalence of early childhood overweight/obesity (COWOB); and (2) influence of young child actual FV intake on the relationship between the FSE and early COWOB prevalence. Anthropometric and socio-demographic data of children (2 to 8 years; N=466) in baseline communities on Guam participating in the Children's Healthy Living (CHL) Program community trial were included...
August 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28805953/factors-associated-with-physical-activity-among-adolescent-and-young-adult-survivors-of-early-childhood-cancer-a-report-from-the-childhood-cancer-survivor-study-ccss
#13
Katie A Devine, Ann C Mertens, John A Whitton, Carmen L Wilson, Kirsten K Ness, Jordan Gilleland Marchak, Wendy Leisenring, Kevin C Oeffinger, Leslie L Robison, Gregory T Armstrong, Kevin R Krull
OBJECTIVE: To evaluate concurrent and longitudinal associations between psychosocial functioning and physical activity in adolescent and young adult survivors of early childhood cancer. METHODS: Adolescent survivors of early childhood cancer (diagnosed before age four) participating in the Childhood Cancer Survivor Study completed the Coping Health and Illness Profile-Adolescent Edition (CHIP-AE; n=303; mean age at survey 17.6 years). A subset of these survivors (n=248) completed a follow-up survey an average of 6...
August 14, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28805465/what-we-are-watching-top-global-infectious-disease-threats-2013-2016-an-update-from-cdc-s-global-disease-detection-operations-center
#14
Kira A Christian, A Danielle Iuliano, Timothy M Uyeki, Eric D Mintz, Stuart T Nichol, Pierre Rollin, J Erin Staples, Ray R Arthur
To better track public health events in areas where the public health system is unable or unwilling to report the event to appropriate public health authorities, agencies can conduct event-based surveillance, which is defined as the organized collection, monitoring, assessment, and interpretation of unstructured information regarding public health events that may represent an acute risk to public health. The US Centers for Disease Control and Prevention's (CDC's) Global Disease Detection Operations Center (GDDOC) was created in 2007 to serve as CDC's platform dedicated to conducting worldwide event-based surveillance, which is now highlighted as part of the "detect" element of the Global Health Security Agenda (GHSA)...
August 14, 2017: Health Security
https://www.readbyqxmd.com/read/28804788/pro-dopamine-regulator-kb220-to-balance-brain-reward-circuitry-in-reward-deficiency-syndrome-rds
#15
Kenneth Blum, Marcelo Febo, Lyle Fried, David Baron, Eric R Braverman, Kristina Dushaj, Mona Li, Zsolt Demetrovics, Rajendra D Badgaiyan
We are faced with a worldwide opiate/opioid epidemic that is devastating. According to the Centers for Disease Control and Prevention (CDC), at least 127 people, young and old, are dying every day in America due to narcotic overdose. The Food and Drug Administration (FDA) has approved Medication-Assisted Treatments (MATs) for opiate/opioids as well as alcohol and nicotine. The mechanism of action of most MATS favors either blocking of dopaminergic function or a form of Opiate Substitution Therapy (OST). These treatment options are adequate for short-term treatment of the symptoms of addiction and harm reduction but fail long-term to deal with the cause or lead to recovery...
2017: Journal of Reward Deficiency Syndrome and Addiction Science
https://www.readbyqxmd.com/read/28804649/trends-and-disparities-in-the-prevalence-of-childhood-obesity-in-south-texas-between-2009-and-2015
#16
Byron A Foster, Trevor M Maness, Christian A Aquino
BACKGROUND: Recent reports have highlighted possible decreases over time in obesity, particularly among children aged 2-5 years. Hispanic children experience significantly higher obesity rates, and less is known about trends for Hispanic children. METHODS: A large healthcare system-based dataset from south Texas was used to analyze body mass index (BMI) values obtained clinically from 2009 through 2015. Age and race/ethnicity specific prevalence of overweight and obesity were calculated using CDC standards and trends were examined over time using regression analyses, and mapping software was used to identify geographic variation...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/28802410/evaluation-of-24-locus-miru-vntr-genotyping-in-mycobacterium-tuberculosis-cluster-investigations-in-four-jurisdictions-in-the-united-states-2006-2010
#17
Larry D Teeter, J Steven Kammerer, Smita Ghosh, Duc T M Nguyen, Padmaja Vempaty, Jane Tapia, Roque Miramontes, Wendy A Cronin, Edward A Graviss
The U.S. Centers for Disease Control and Prevention (CDC) uses a combination of spacer oligonucleotide typing (spoligotyping) and mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) analyses as part of the National TB Genotyping Service (NTGS). The NTGS expansion from 12-locus MIRU-VNTR (MIRU12) to 24-locus MIRU-VNTR (MIRU24) in 2009 enhanced the ability to discriminate Mycobacterium tuberculosis strains. In the current study, we investigated the MIRU24 concordance among epidemiologic-linked tuberculosis (TB) patients in four U...
September 2017: Tuberculosis
https://www.readbyqxmd.com/read/28802255/simultaneous-targeting-of-two-distinct-epitopes-on-met-effectively-inhibits-met-and-hgf-driven-tumor-growth-by-multiple-mechanisms
#18
Michael M Grandal, Serhiy Havrylov, Thomas Tuxen Poulsen, Klaus Koefoed, Anna Dahlman, Gunther R Galler, Paolo Conrotto, Sara Collins, Karsten W Eriksen, Dafna Kaufman, George F Vande Woude, Helle J Jacobsen, Ivan D Horak, Michael Kragh, Johan Lantto, Thomas Bouquin, Morag Park, Mikkel Wandahl Pedersen
Increased MET activity is linked with poor prognosis and outcome in several human cancers currently lacking targeted therapies. Here we report on the characterization of Sym015, an antibody mixture composed of two humanized IgG1 antibodies against non-overlapping epitopes of MET. Sym015 was selected by high-throughput screening searching for antibody mixtures with superior growth inhibitory activity against MET-dependent cell lines. Synergistic inhibitory activity of the antibodies comprising Sym015 was observed in several cancer cell lines harboring amplified MET locus and was confirmed in vivo Sym015 was found to exert its activity via multiple mechanisms...
August 11, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28802050/distinct-dc-subsets-regulate-adaptive-th1-and-2-responses-during-trichuris-muris-infection
#19
Mimoza Demiri, Katarzyna Müller-Luda, William W Agace, Marcus Svensson-Frej
Low and high-dose infections with the murine large-intestinal nematode Trichuris muris are associated with induction of adaptive Th1 and Th2 responses, respectively, in mesenteric lymph nodes (MLN). Classical dendritic cells (cDC) accumulate in the large-intestinal mucosa and MLN upon T. muris infection, yet their role in driving adaptive responses to infection remains largely unknown. We performed low and high-dose T. muris infections of mice deficient in defined cDC subsets to investigate their role in induction of adaptive immune responses...
August 12, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28801832/simultaneous-measurement-of-total-estradiol-and-testosterone-in-human-serum-by-isotope-dilution-liquid-chromatography-tandem-mass-spectrometry
#20
Hui Zhou, Yuesong Wang, Matthew Gatcombe, Jacob Farris, Julianne C Botelho, Samuel P Caudill, Hubert W Vesper
Reliable measurement of total testosterone and estradiol is critical for their use as biomarkers of hormone-related disorders in patient care and translational research. We developed and validated a mass spectrometry method to simultaneously quantify these analytes in human serum without chemical derivatization. Serum is equilibrated with isotopic internal standards and treated with acidic buffer to release hormones from their binding proteins. Lipids are isolated and polar impurities are removed by two serial liquid-liquid extraction steps...
August 11, 2017: Analytical and Bioanalytical Chemistry
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