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https://www.readbyqxmd.com/read/28639035/mitigation-of-pedestrian-heat-stress-using-parasols-in-a-humid-subtropical-region
#1
Shinichi Watanabe, Jin Ishii
Concerns over heat illness have been an increasing social problem in humid subtropical regions. One measure for avoiding excessive heat stress in hot outdoor environments is the use of parasols or umbrellas. The advantage of parasols is that they are a mobile and inexpensive way to provide personal shade outdoors. The objectives of this study were to compare the wet-bulb globe temperature (WBGT) under parasols and at an unshaded point as a reference, and to quantify the reduction in WBGT from the use of parasols in a humid subtropical region...
June 21, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28623037/muscle-recruitment-and-coordination-with-an-ankle-exoskeleton
#2
Katherine M Steele, Rachel W Jackson, Benjamin R Shuman, Steven H Collins
Exoskeletons have the potential to assist and augment human performance. Understanding how users adapt their movement and neuromuscular control in response to external assistance is important to inform the design of these devices. The aim of this research was to evaluate changes in muscle recruitment and coordination for ten unimpaired individuals walking with an ankle exoskeleton. We evaluated changes in the activity of individual muscles, cocontraction levels, and synergistic patterns of muscle coordination with increasing exoskeleton work and torque...
May 18, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28603496/anhuienoside-c-ameliorates-collagen-induced-arthritis-through-inhibition-of-mapk-and-nf-%C3%AE%C2%BAb-signaling-pathways
#3
Qing Liu, Xu-Hui Xiao, Liu-Bing Hu, Hui-Yang Jie, Ying Wang, Wen-Cai Ye, Man-Mei Li, Zhong Liu
Anemone flaccida Fr. Schmidt (Ranunculaceae) (Di Wu in Chinese) is used to treat punch injuries and rheumatoid arthritis (RA). Our previous report has shown that crude triterpenoid saponins from Anemone flaccida exhibited anti-arthritic effects on type II collagen-induced arthritis in rats. Furthermore, anhuienoside C (AC), a saponin compound isolated from A. flaccida, was observed to suppress the nitric oxide production in lipopolysaccharide (LPS)-treated macrophage RAW 264.7 cells. In this study, we examined the effects of AC on the prevention and treatment of collagen-induced arthritis in a mouse model and evaluated the potential mechanisms involved...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28595744/functional-electrical-stimulation-improves-quality-of-life-by-reducing-intermittent-claudication
#4
David G Embrey, Gad Alon, Brenna A Brandsma, Felix Vladimir, Angela Silva, Bethann M Pflugeisen, Paul J Amoroso
OBJECTIVE: To determine if Functional Electrical Stimulation (FES) would improve ischemic pain, walking distance, and quality of life of patients with intermittent claudication. DESIGN: Single blind, randomized block, two factorial design. PATIENTS: Patients diagnosed with Peripheral Artery Disease (PAD) and intermittent claudication (IC). Ankle Brachial Index ranged 0.4-0.9 on at least one leg. Patients were randomly assigned to experimental (FES+Walk, N=13) or control (WALK, N=14) groups...
June 2, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28576901/anankle-trial-study-protocol-a-randomised-trial-comparing-pain-profiles-after-peripheral-nerve-block-or-spinal-anaesthesia-for-ankle-fracture-surgery
#5
Rune Sort, Stig Brorson, Ismail Gögenur, Ann Merete Møller
INTRODUCTION: Ankle fracture surgery is a common procedure, but the influence of anaesthesia choice on postoperative pain and quality of recovery is poorly understood. Some authors suggest a benefit of peripheral nerve block (PNB) in elective procedures, but the different pain profile following acute fracture surgery and the rebound pain on cessation of the PNB both remain unexplored. We present an ongoing randomised study aiming to compare primary PNB anaesthesia with spinal anaesthesia for ankle fracture surgery regarding postoperative pain profiles and quality of recovery...
June 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28542868/initial-placement-and-secondary-displacement-of-a-new-suture-method-catheter-for-sciatic-nerve-block-in-healthy-volunteers-a-randomised-double-blind-pilot-study
#6
T S Lyngeraa, C Rothe, C Steen-Hansen, M H Madsen, C B Christiansen, A M Andreasen, L H Lundstrøm, K H W Lange
We performed a randomised double-blind pilot study in 16 healthy volunteers to investigate the success rate for placing a new suture-method catheter for sciatic nerve block. A catheter was inserted into both legs of volunteers and each was randomly allocated to receive 15 ml lidocaine 2% through the catheter in one leg and 15 ml saline in the other leg. Successful placement of the catheter was defined as a 20% decrease in maximum voluntary isometric contraction for dorsiflexion of the ankle. Secondary outcomes were maximum voluntary isometric contraction for plantar flexion at the ankle, surface electromyography and cold sensation...
May 25, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28533627/reduced-foot-pain-after-spasticity-control-with-alcohol-block-in-a-patient-with-chronic-hemiparetic-stroke-a-case-report
#7
Min Cheol Chang
[Purpose] This study report a case of a patient with hemiparetic stroke who showed significantly reduced foot pain when ankle spasticity was reduced using nerve and motor point blocks with 20% ethyl alcohol. [Subject and Methods] A 58-year-old woman with left hemiparesis following intracranial hemorrhage five years previously presented with pain in the left fifth metatarsal head for two years (numeric rating scale[NRS]: 8). Erythema and edema were observed on the lateral aspect of the head of the fifth metatarsal bone...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28483557/six-week-transition-to-minimalist-shoes-improves-running-economy-and-time-trial-performance
#8
Joel T Fuller, Dominic Thewlis, Margarita D Tsiros, Nicholas A T Brown, Jonathan D Buckley
OBJECTIVES: This study investigated if gradually introducing runners to minimalist shoes during training improved running economy and time-trial performance compared to training in conventional shoes. Changes in stride rate, stride length, footfall pattern and ankle plantar-flexor strength were also investigated. DESIGN: Randomised parallel intervention trial. METHODS: 61 trained runners gradually increased the amount of running performed in either minimalist (n=31) or conventional (n=30) shoes during a six-week standardised training program...
April 21, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28466759/knee-ankle-foot-orthosis-with-powered-knee-for-support-in-the-elderly
#9
Peter Paul Pott, Sebastian Immanuel Wolf, Julia Block, Stefan van Drongelen, Markus Grün, Daniel Ww Heitzmann, Jürgen Hielscher, Andreas Horn, Roman Müller, Oliver Rettig, Ulrich Konigorski, Roland Werthschützky, Helmut Friedrich Schlaak, Thorsten Meiß
A prototype of a powered knee orthotic device was developed to determine whether fractional external torque and power support to the knee relieves the biomechanical loads and reduces the muscular demand for a subject performing sit-to-stand movements. With this demonstrator, consisting of the subsystems actuation, kinematics, sensors, and control, all relevant sensor data can be acquired and full control is maintained over actuator parameters. A series-elastic actuator based on a direct current motor provides up to 30 Nm torque to the knee via a hinge joint with an additional sliding degree of freedom...
May 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28463993/periploca-forrestii-saponin-ameliorates-cia-via-suppressing-proinflammatory-cytokines-and-nuclear-factor-kappa-b-pathways
#10
Chunmei Bao, Yingqin Liu, Xin Sun, Congcong Xing, Luting Zeng, Guangchen Sun
OBJECTIVE: Periploca forrestii Schltr has been used as a Chinese folk medicine for the treatment of rheumatism, arthralgia and fractures. However, the anti-arthritic activity of Periploca forrestii saponin (PFS) and the active compound has still not been revealed. This study aimed to investigate the protective effects and mechanisms of PFS on collagen type II (CII) collagen-induced arthritis (CIA) mice. We sought to investigate whether PFS and Periplocin could regulate osteoclastogenesis, and if so, further investigation on its mechanism of action...
2017: PloS One
https://www.readbyqxmd.com/read/28451697/assessment-and-treatment-of-spastic-equinovarus-foot-after-stroke-guidance-from-the-mont-godinne-interdisciplinary-group
#11
Thierry Deltombe, Delphine Wautier, Philippe De Cloedt, Michèle Fostier, Thierry Gustin
OBJECTIVE: To present interdisciplinary practical guidance for the assessment and treatment of spastic equinovarus foot after stroke. RESULTS: Clinical examination and diagnostic nerve block with anaesthetics determine the relative role of the factors leading to spastic equinovarus foot after stroke: calf spasticity, triceps surae - Achilles tendon complex shortening and dorsiflexor muscles weakness and/or imbalance. Diagnostic nerve block is a mandatory step in determining the cause(s) of, and the most appropriate treatment(s) for, spastic equinovarus foot...
April 26, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28448704/-retrograde-intramedullary-nail-fixation-for-charcot-neuroarthropathy
#12
E López-Gavito, N A Gómez-Fuentes, P Parra-Téllez, M Lezama-Peniche, J Vázquez-Escamilla, S R León-Hernández
Charcot arthropathy is defined as an articular degenerative, chronic, progressive disease that affects one or more peripheral joints, develops as a result of a failure in the normal sensory perception (pain and proprioception) in the innervation of joints located in the foot and ankle, is characterized by destructive bone lesions without the presence of infection. Neuropathy is directly associated with diabetes mellitus type 1 and 2. Surgery is indicated when there is severe involvement of soft tissue, foot joints are unstable, at the presence of chronic or recurrent ulcers or when the foot and ankle can not fit to a normal shoe, and had limitation to perform activities of daily living...
September 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28403379/effect-of-resveratrol-on-walking-performance-in-older-people-with-peripheral-artery-disease-the-restore-randomized-clinical-trial
#13
Mary M McDermott, Christiaan Leeuwenburgh, Jack M Guralnik, Lu Tian, Robert Sufit, Lihui Zhao, Michael H Criqui, Melina R Kibbe, James H Stein, Donald Lloyd-Jones, Stephen D Anton, Tamar S Polonsky, Ying Gao, Rafael de Cabo, Luigi Ferrucci
Importance: Research shows that resveratrol, a sirtuin activator in red wine, improves exercise endurance and skeletal-muscle oxidative metabolism in animals and may enhance vascular function in humans. Resveratrol supplement sales exceed $30 million annually in the United States, but few data are available regarding its efficacy in humans. Objective: To determine whether resveratrol, 125 mg/d or 500 mg/d, improves the 6-minute walk performance in patients with peripheral artery disease (PAD)...
April 12, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28348185/surgery-for-type-b-ankle-fracture-treatment-a-combined-randomised-and-observational-study-crossbat
#14
Rajat Mittal, Ian A Harris, Sam Adie, Justine M Naylor
BACKGROUND: Isolated type B ankle fractures with no injury to the medial side are the most common type of ankle fracture. OBJECTIVE: This study aimed to determine if surgery is superior to non-surgical management for the treatment of these fractures. METHODS: A pragmatic, multicentre, single-blinded, combined randomised controlled trial and observational study. Setting Participants between 18 and 65 years with a type B ankle fracture and minimal talar shift were recruited from 22 hospitals in Australia and New Zealand...
March 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28260202/biochemical-responses-and-physical-performance-during-high-intensity-resistance-circuit-training-in-hypoxia-and-normoxia
#15
RANDOMIZED CONTROLLED TRIAL
Domingo J Ramos-Campo, Jacobo A Rubio-Arias, Stéphane Dufour, Linda Chung, Vicente Ávila-Gandía, Pedro E Alcaraz
PURPOSE: The aim of this study was to analyze the effect of hypoxia on metabolic and acid-base balance, blood oxygenation, electrolyte, and half-squat performance variables during high-resistance circuit (HRC) training. METHODS: Twelve resistance-trained subjects participated in this study. After a 6RM testing session, participants performed three randomized trials of HRC: normoxia (NORM: FiO2 = 0.21), moderate hypoxia (MH: FiO2 = 0.16), or high hypoxia (HH: FiO2 = 0...
April 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28247430/a-novel-phase-unwrapping-method-based-on-pixel-clustering-and-local-surface-fitting-with-application-to-dixon-water-fat-mri
#16
Junying Cheng, Yingjie Mei, Biaoshui Liu, Jijing Guan, Xiaoyun Liu, Ed X Wu, Qianjin Feng, Wufan Chen, Yanqiu Feng
PURPOSE: To develop and evaluate a novel 2D phase-unwrapping method that works robustly in the presence of severe noise, rapid phase changes, and disconnected regions. THEORY AND METHODS: The MR phase map usually varies rapidly in regions adjacent to wraps. In contrast, the phasors can vary slowly, especially in regions distant from tissue boundaries. Based on this observation, this paper develops a phase-unwrapping method by using a pixel clustering and local surface fitting (CLOSE) approach to exploit different local variation characteristics between the phase and phasor data...
March 1, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28235517/partial-displacement-of-epidural-catheter-after-patient-position-change-a-case-report
#17
Yoon-Jung Shon, Seung-Kil Bae, Jae-Woo Park, In-Nam Kim, Jin Huh
Epidural catheter migration is a well-known cause of failed anesthesia and complications. One of the factors that affect catheter movement is when patients change their position after skin fixation. We report a case of an epidural catheter placed without evidence of intravascular or subdural insertion that produced an insufficient block. A 36-year-old woman presented for ankle surgery under epidural anesthesia. Epidural block was conducted at the L3-4 intervertebral space with a catheter threaded 3 cm into the epidural space with the patient in a back flexion and lateral position...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28139190/patient-specific-instrumentation-for-total-knee-arthroplasty
#18
Arash Nabavi, Caroline M Olwill, Mike Do, Tanya Wanasawage, Ian A Harris
PURPOSE: To assess the accuracy of total knee replacements (TKRs) performed using CT-based patient-specific instrumentation by postoperative CT scan. METHOD: Approval from the Ethics Committee was granted prior to commencement of this study. Fifty prospective and consecutive patients who had undergone TKR (Evolis, Medacta International) using CT-based patient-specific instrumentation (MY KNEE, Medacta International) were assessed postoperatively using a CT scan and the validated Perth protocol measurement technique...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28111159/benefit-of-adding-fibular-osteotomy-to-open-wedge-valgus-distal-tibial-osteotomy-for-correcting-varus-ankle-arthritis-an-in%C3%A2-vitro-study
#19
Thos Harnroongroj, Bavornrit Chuckpaiwong
Early-stage varus ankle arthritis can usually be treated with a medial, open-wedge, valgus, distal tibial osteotomy; however, the value of adding a fibular osteotomy has been debated. We sought to determine the increase in the maximum medial osteotomy gap and correction angle provided by fibular osteotomy. In 3 sequential experiments on 12 fresh cadaveric legs, we first performed a medial open-wedge, valgus, distal tibial osteotomy alone. Second, we added a transverse fibular osteotomy. Finally, we added a blocked fibular osteotomy...
March 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28033291/adductor-canal-block-versus-femoral-nerve-block-combined-with-sciatic-nerve-block-as-an-anesthetic-technique-for-hindfoot-and-ankle-surgery-a-prospective-randomized-noninferiority-trial
#20
RANDOMIZED CONTROLLED TRIAL
Han Bum Joe, Ho Sik Choo, Ji Sang Yoon, Sang Eon Oh, Jae Ho Cho, Young Uk Park
BACKGROUND: A femoral nerve block (FNB) in combination with a sciatic nerve block (SNB) is commonly used for anesthesia and analgesia in patients undergoing hindfoot and ankle surgery. The effects of FNB on motor function, related fall risk, and rehabilitation are controversial. An adductor canal block (ACB) potentially spares motor fibers in the femoral nerve, but the comparative effect on hindfoot and ankle surgeries between the 2 approaches is not yet well defined. We hypothesized that compared to FNB, ACB would cause less weakness in the quadriceps and produce similar pain scores during and after the operation...
December 2016: Medicine (Baltimore)
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