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https://www.readbyqxmd.com/read/29772572/lack-of-equipoise-on-ankle-block-after-hallux-valgus-surgery
#1
Mark C Kendall, Lucas Castro Alves
No Abstract.
May 17, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29770503/a-novel-phase-unwrapping-method-by-using-phase-jump-detection-and-local-surface-fitting-application-to-dixon-water-fat-mri
#2
Junying Cheng, Jijing Guan, Yingjie Mei, Lin Xu, Xiaoyun Liu, Qianjin Feng, Wufan Chen, Yanqiu Feng
PURPOSE: This study aims to develop an accurate and robust phase-unwrapping method that works effectively under severe noise, rapid-varying phase, and disconnected regions for water-fat Dixon MRI. METHODS: The proposed method first segments the phase map into blocks by automatically detecting phase jumps, and then clusters the pixels near phase jumps into residual pixels. Thereafter, the proposed method sequentially performs intrablock, interblock, and residual-pixel unwrapping using the local surface fitting approach...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29768121/a-biomechanical-comparison-of-initial-sprint-acceleration-performance-and-technique-in-an-elite-athlete-with-cerebral-palsy-and-able-bodied-sprinters
#3
Ian N Bezodis, James Cowburn, Adam Brazil, Rhian Richardson, Cassie Wilson, Timothy A Exell, Gareth Irwin
Cerebral palsy is known to generally limit range of motion and force producing capability during movement. It also limits sprint performance, but the exact mechanisms underpinning this are not well known. One elite male T36 multiple-Paralympic sprint medallist (T36) and 16 well-trained able-bodied (AB) sprinters each performed 5-6 maximal sprints from starting blocks. Whole-body kinematics (250 Hz) in the block phase and first two steps, and synchronised external forces (1,000 Hz) in the first stance phase after block exit were combined to quantify lower limb joint kinetics...
May 16, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29762181/intraneural-ultrasound-guided-sciatic-nerve-block-minimum-effective-volume-and-electrophysiologic-effects
#4
Gianluca Cappelleri, Andrea Luigi Ambrosoli, Marco Gemma, Valeria Libera Eva Cedrati, Federico Bizzarri, Giorgio Francesco Danelli
BACKGROUND: Both extra- and intraneural sciatic injection resulted in significant axonal nerve damage. This study aimed to establish the minimum effective volume of intraneural ropivacaine 1% for complete sensory-motor sciatic nerve block in 90% of patients, and related electrophysiologic variations. METHODS: Forty-seven consecutive American Society of Anesthesiologists physical status I-II patients received an ultrasound-guided popliteal intraneural nerve block following the up-and-down biased coin design...
May 15, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29761788/block-based-robust-control-of-stepping-using-intraspinal-microstimulation
#5
Ehsan Rouhani, Abbas Erfanian
OBJECTIVE: The problem of motor control using intraspinal microstimulation (ISMS) can be approached at two levels of the motor system: individual muscles (motor pools) and motor primitives. The major challenges of direct ISMS at the level of individual muscle are the number of electrodes that are required to be implanted in order to recruit all muscles involving the motion and the muscle selectivity. One solution to cope with these problems is the control of movement generated by appropriate combination of the movement primitives...
May 15, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29752218/elevated-international-normalized-ratio-is-not-associated-with-increased-perioperative-morbidity-in-podiatric-limb-salvage-surgery-a-retrospective-analysis
#6
Nalini Vadivelu, Alice M Kai, Feng Dai, Hosni Mikhael, Rima Aouad, Peter Blume
The risk of hemorrhage always exists in anticoagulated patients with an elevated international normalized ratio (INR), a risk that must be measured against the necessity for surgical procedures. The objective of the present retrospective medical record study was to assess the safety with which limb salvage procedures can be conducted in patients with an INR >1.4. The medical records of 231 patients who had undergone limb salvage procedures by 1 surgeon at the Yale New Haven Health System from November 2008 through July 2014 were reviewed...
May 8, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29750395/adamts-12-protects-against-inflammatory-arthritis-through-interacting-with-and-inactivating-proinflammatory-ctgf
#7
Jian-Lu Wei, Wenyu Fu, Aubryanna Hettinghouse, Wen-Jun He, Kenneth E Lipson, Chuan-Ju Liu
OBJECTIVE: It has been reported that a disintegrin and metalloproteinase with thrombospondin motifs-12 (ADAMTS-12) is a susceptibility gene for rheumatoid arthritis (RA) development, and its level is significantly increased in RA patients. In addition, ADAMTS-12 was also reported to be required for normal inflammation. This study aims to determine the role of ADAMTS-12 and the underlying mechanisms in the pathogenesis of inflammatory arthritis. METHODS: The collagen-induced arthritis (CIA) model was established in ADAMTS-12-deficient mice and their control littermates to determine the role of ADAMTS-12 in vivo; microCT scanning was used to demonstrate the destruction of ankle joint; histological analysis illustrated synovitis, pannus formation, as well as bone and cartilage destruction; ELISA was performed to measure serum levels of inflammatory cytokines; Protein-protein interaction assays were performed to detect the interactions of ADAMTS-12 and its various deletion mutants with connective tissue growth factor (CTGF)...
May 11, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29748103/gabapentin-as-an-adjunct-to-standard-postoperative-pain-management-protocol-in-lower-extremity-surgery
#8
REVIEW
P Andrew Crisologo, Erik K Monson, Said A Atway
Postoperative pain is a problem that plagues physicians and has since the dawn of the surgical arts. Many interventions are available and used as the standard such as preoperative local anesthetic blocks, opiates, both oral and intravenous, and nonsteroidal antiinflammatory drugs. Although the temptation often exists to increase the postoperative opiate dose, opiate abuse is an increasing problem. This abuse has fueled the search for nonopiate pain adjuncts. Gabapentinoids have been shown to both decrease postoperative pain and, secondarily, decrease opiate dependence...
May 7, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29719192/response-to-letter-regarding-combined-popliteal-catheter-with-single-injection-vs-continuous-infusion-saphenous-nerve-block-for-foot-and-ankle-surgery
#9
Steven M Raikin, Kathleen Jarrell, Elizabeth McDonald, Rachel Shakked, Kristen Nicholson, Vincent Kasper
No abstract text is available yet for this article.
May 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29719191/letter-regarding-combined-popliteal-catheter-with-single-injection-vs-continuous-infusion-saphenous-nerve-block-for-foot-and-ankle-surgery
#10
Mark C Kendall
No abstract text is available yet for this article.
May 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29667940/the-importance-of-the-saphenous-nerve-block-for-analgesia-following-major-ankle-surgery-a-randomized-controlled-double-blind-study
#11
Siska Bjørn, Wan Yi Wong, Jørgen Baas, Kristian K Nielsen, Jens Børglum, Rasmus Wulff Hauritz, Thomas Fichtner Bendtsen
BACKGROUND AND OBJECTIVES: Major ankle surgery causes intense postoperative pain, and whereas the importance of a sciatic nerve block is well established, the clinical significance of a supplemental saphenous nerve block has never been determined in a prospective, randomized, double-blind, placebo-controlled trial. We hypothesized that a saphenous nerve block reduces the proportion of patients experiencing significant clinical pain after major ankle surgery. METHODS: Eighteen patients were enrolled and received a popliteal sciatic nerve block...
March 26, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29655702/4-2-4-chlorophenyl-1-4-chlorophenyl-amino-ethyl-benzene-1-3-diol-is-a-potential-agent-for-gout-therapy-as-a-dual-inhibitor-of-xod-and-nlrp3
#12
Mengze Zhou, Suning Li, Ling Song, Qinghua Hu, Wentao Liu
BACKGOUND: Gout is an inflammatory arthritis characterized by abrupt self-limiting attacks of inflammation caused by precipitation of monosodium urate crystals (MSU) in the joint. Both anti-hyperuricemia and anti-inflammation could be gout therapeutic strategies, whereas ideal drugs for gout treatment are deficient. PURPOSE: 4-(2-(4-chlorophenyl)-1-((4-chlorophenyl)amino)ethyl)benzene-1, 3-diol (CBED) was obtained from a cluster of deoxybenzoins derivatives synthesized by our research group with potent anti-hyperuricemic and anti-inflammatory activities, which was expected to be a dual inhibitor of xanthine oxidase (XOD) and NOD-like receptor protein 3 (NLRP3)...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29630032/perineural-versus-systemic-dexamethasone-in-front-foot-surgery-under-ankle-block-a-randomized-double-blind-study
#13
Philippe Marty, Olivier Rontes, Clément Chassery, Corine Vuillaume, Bertrand Basset, Mehdi Merouani, Constance Marquis, Benoit Bataille, Martine Chaubard, Marie Claude Mailles, Fabrice Ferré, Alain Delbos
BACKGROUND AND OBJECTIVES: Among the different adjuvants, dexamethasone is one of the most accepted to prolong the effect of local anesthetics. This study aims to determine the superiority of perineural over systemic dexamethasone administration after a single-shot ankle block in metatarsal osteotomy. METHODS: We performed a prospective, double-blind, randomized study. A total of 100 patients presenting for metatarsal osteotomy with an ankle block were randomized into 2 groups: 30 mL ropivacaine 0...
April 6, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29620988/a-simple-guide-to-regional-anaesthesia
#14
E M Valsamis, S Wade, C Thornhill, C Carey, D Ricketts
Regional anaesthesia is widely used in modern anaesthetic practice for perioperative and postoperative analgesia. In the operating theatre, regional anaesthesia is used both on its own and in combination with other techniques (general anaesthesia and sedation). Regional anaesthesia is now a core skill set in anaesthetic training. This article provides a basic outline of regional anaesthesia for surgeons and other non-anaesthetic staff working with anaesthetists, reviewing preparation, consent, basic and specialist equipment, central neuraxial blocks (spinal, epidural and caudal), trunk blocks, upper limb blocks (interscalene, supraclavicular, infraclavicular and axillary) and lower limb blocks (femoral, fascia iliaca, sciatic, popliteal and ankle)...
April 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29529607/ankle-nerve-block-adjuvant-to-general-anesthesia-reduces-post-surgical-pain-and-improves-functional-outcomes-in-hallux-valgus-surgery
#15
Mustafa Kir, Gulay Kir
OBJECTIVE: Postoperative pain is a frequently problem after orthopedic procedures like hallux valgus surgery. The aim of this study was to evaluate whether ankle block improves early and mid-term functional outcomes and postoperative pain management after hallux valgus surgery in patients receiving general anesthesia. SUBJECTS AND METHODS: This randomized controlled trial investigated 60 patients who underwent hallux valgus surgery under general anesthesia. Patients were prospectively randomized into two groups; general anesthesia only (Group A) and ankle block added to general anesthesia (Group B)...
March 12, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29506395/opioid-consumption-following-foot-and-ankle-surgery
#16
Haley M Merrill, Daniel M Dean, Jay L Mottla, Steven K Neufeld, Daniel J Cuttica, Matthew M Buchanan
Background Orthopaedic surgeons frequently prescribe pain medications during the postoperative period. The efficacy of these medications at alleviating pain after foot/ankle surgery and the quantity of medication required (and conversely, leftover) are unknown. METHODS: Patients undergoing foot/ankle surgery during a 3-month period who met inclusion criteria were surveyed at their first postoperative visit. Information collected included gender, number of prescribed pills remaining, satisfaction with pain control, and willingness to surrender leftover opioids to a Drug Enforcement Administration (DEA) disposal center...
March 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29485127/norepinephrine-inhibits-th17-cells-via-%C3%AE-2-adrenergic-receptor-%C3%AE-2-ar-signaling-in-a-mouse-model-of-rheumatoid-arthritis
#17
Yan Liu, Xiao-Xiao Rui, Hui Shi, Yi-Hua Qiu, Yu-Ping Peng
BACKGROUND Norepinephrine (NE), a neurotransmitter released from the sympathetic nerves, has been shown to be involved in rheumatoid arthritis (RA). However, its role in the sympathetic nervous system in RA is divergent. Herein, we demonstrate that the sympathetic neurotransmitter NE exerts an anti-inflammatory effect in collagen-induced arthritis (CIA), a mouse model of RA, by inhibiting Th17 cell differentiation and function via β2-adrenergic receptor (β2-AR) signaling. MATERIAL AND METHODS CIA was prepared by intradermal injection of collagen type II in the tail base of DBA1/J mice...
February 27, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29422077/adiponectin-aggravates-bone-erosion-by-promoting-osteopontin-production-in-synovial-tissue-of-rheumatoid-arthritis
#18
Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan, Miaojia Zhang
BACKGROUND: We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates well with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD in promoting joint destruction remains unclear. Osteopontin (OPN) is required for osteoclast recruitment. We hypothesized that AD exacerbates bone erosion by inducing OPN expression in synovial tissue. This study aimed to evaluate a novel role for AD in RA. METHODS: The serum levels of AD and OPN were determined in 38 patients with RA, 40 patients with osteoarthritis (OA), and 20 healthy controls using enzyme-linked immunosorbent assay (ELISA)...
February 8, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29409271/comparison-of-postoperative-pain-control-methods-after-bony-surgery-in-the-foot-and-ankle
#19
Chan Kang, Gi-Soo Lee, Sang-Bum Kim, You-Gun Won, Jeong-Kil Lee, You-Sun Jung, Hyung-June Cho
BACKGROUND: We performed a prospective study to evaluate and compare the effectiveness of postoperative pain control methods after bone surgery in the foot and ankle. METHODS: Among the patients who underwent foot and ankle surgery from June 2014 to September 2015 with an ultrasound-guided nerve block, 84 patients who fully completed a postoperative pain survey were enrolled. An opioid patch (fentanyl patch, 25mg) was applied in group A (30 patients). Diluted anesthetic (0...
June 24, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29374988/the-effects-of-timing-of-ankle-blocks-in-forefoot-midfoot-or-hindfoot-reconstruction-with-the-use-of-an-ankle-tourniquet
#20
James Gwosdz, Lattisha Bilbrew, Daniel Jupiter, Vinod Panchbhavi
BACKGROUND: Ankle blocks are used in the ambulatory surgery setting to control postoperative pain, which is often worst in the first 24 hours after surgery. We conducted a trial to determine whether the timing of ankle block administration in relation to ankle tourniquet inflation has an effect on perceived pain and narcotic consumption. METHODS: A prospective randomized study was conducted between August 2015 and January 2016. Patients were assigned to three groups...
January 1, 2018: Foot & Ankle Specialist
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