keyword
https://read.qxmd.com/read/38645991/dexamethasone-versus-dexmedetomidine-as-adjuvants-in-ultrasound-popliteal-sciatic-nerve-block-for-hallux-valgus-surgery-a-mono-centric-retrospective-comparative-study
#1
JOURNAL ARTICLE
Antonio Coviello, Carmine Iacovazzo, Dario Cirillo, Alessio Bernasconi, Annachiara Marra, Francesco Squillacioti, Marco Martone, Eleonora Garone, Filomena Coppola, Andrea Uriel de Siena, Maria Vargas, Giuseppe Servillo
BACKGROUND AND AIM: Ultrasound popliteal sciatic nerve block (UPSNB) is commonly performed in foot and ankle surgery. This study aims to assess the use of dexmedetomidine and dexamethasone as adjuvants in UPSNB for hallux valgus (HV) surgery, comparing their efficacy in producing motor and sensory block and controlling postoperative pain. The adverse event rate was also evaluated. METHODS: This mono-centric retrospective study included 62 adult patients undergoing HV surgery: 30 patients received lidocaine 2% 200 mg, ropivacaine 0...
2024: Drug Design, Development and Therapy
https://read.qxmd.com/read/38597439/-lung-protective-effect-of-esketamine-combined-with-distal-limb-ischemic-preconditioning-in-elderly-patients-undergoing-thoracoscopic-radical-surgery-for-lung-cancer-a-randomized-controlled-trial-in-160-cases
#2
JOURNAL ARTICLE
Y Yang, G Liu, Y Ou, W Lu
OBJECTIVE: To evaluate the effect of esketamine combined with distal limb ischemic preconditioning (LIP) for lung protection in elderly patients undergoing thoracoscopic radical surgery for lung cancer. METHODS: This randomized trial was conducted in 160 patients undergoing elective thoracoscopic surgery for lung cancer, who were randomized into control group (with saline injection and sham LIP), esketamine group, LIP group, and esketamine + LIP group ( n =40). Before anesthesia induction, according to the grouping, the patients received an intravenous injection with 0...
March 20, 2024: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://read.qxmd.com/read/38579041/comparing-quality-of-recovery-and-satisfaction-between-spinal-anesthesia-and-nerve-block-in-orthopedic-below-knee-surgery-a-prospective-controlled-trial
#3
JOURNAL ARTICLE
Seon Woo Yoo, Taehoon Kim, Jongmin Seo, Hyunji Oh, Jun Ho Lee
BACKGROUND: Postoperative quality of recovery (QoR) and patient satisfaction have gained increasing significance in medical services. This study aimed to compare these 2 parameters between 2 types of regional anesthetics (spinal anesthesia and combined sciatic-femoral nerve block) in orthopedic lower knee surgery. METHODS: A total of 101 patients were classified into 2 groups (combined sciatic-femoral nerve block, group N; spinal anesthesia, group S) according to patient preference...
April 5, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38574504/the-effectiveness-of-ambulatory-continuous-popliteal-sciatic-nerve-blockade-on-patient-reported-overall-benefit-of-analgesia-in-patients-undergoing-foot-or-ankle-surgery-carefree-trial-a-randomized-open-label-non-inferiority-trial
#4
JOURNAL ARTICLE
Manouk Admiraal, Pascal S H Smulders, Martin V H Rutten, Eelko K de Groot, Yvonne Heine, Holger M Baumann, Vincent H C van der Vegt, Jens A Halm, Henning Hermanns, Tim Schepers, Markus W Hollmann, Jeroen Hermanides, Werner Ten Hoope
STUDY OBJECTIVE: Management of pain after foot and ankle surgery remains a concern for patients and healthcare professionals. This study determined the effectiveness of ambulatory continuous popliteal sciatic nerve blockade, compared to standard of care, on overall benefit of analgesia score (OBAS) in patients undergoing foot or ankle surgery. We hypothesized that usage of ambulatory continuous popliteal sciatic nerve blockade is non-inferior to standard of care. DESIGN: Single center, randomized, non-inferiority trial...
April 3, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38571656/intravenous-injection-of-dexamethasone-is-non-inferior-to-perineural-administration-for-popliteal-sciatic-nerve-and-saphenous-nerve-blocks-a-randomized-controlled-triple-blind-study
#5
JOURNAL ARTICLE
Guiyu Lei, Siliu Yang, Lili Wu, Yue Yin, Shu Zhang, Guyan Wang
BACKGROUND: The aim of this study was to assess whether intravenous dexamethasone was noninferior to perineural dexamethasone as an adjuvant to ropivacaine for a combination of saphenous and sciatic nerve blocks in patients undergoing foot and ankle surgery. METHODS: This was a prospective, blinded, randomized noninferiority study. Seventy-five patients, aged 18-75 years, with an American Society of Anesthesiologists (ASA) physical status I-III who underwent foot and ankle surgery were involved...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38551026/a-cadaveric-study-investigating-the-spread-of-injectate-following-an-interspace-between-the-popliteal-artery-and-the-capsule-of-the-posterior-knee-block-in-a-neonatal-sample-a-pilot-study
#6
JOURNAL ARTICLE
Sabashnee Govender-Davies, Llewellyn Davies, Sashrika Pillay-Addinall
The infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK) block, is a novel ultrasound-guided technique used for postoperative pain management of the knee. The success of the block is attributed to the spread of injectate between the capsule of the knee and the popliteal artery. This novel technique is believed to target the articular branches of the tibial, common fibular (peroneal) and obturator nerves. However, the extent of the spread in a paediatric population is unknown...
March 29, 2024: Anatomy & Cell Biology
https://read.qxmd.com/read/38510888/sustained-relief-of-complex-regional-pain-syndrome-crps-pain-following-a-60-day-peripheral-nerve-stimulation-a-report-of-three-cases
#7
Genaro J Gutierrez, Claire A Zurn, Nathan D Crosby
Patients who present to pain clinics with complex regional pain syndrome (CRPS) typically have debilitating pain, including hyperalgesia and allodynia, and additional substantial quality-of-life concerns related to the motor and autonomic-related symptoms of CRPS. Present treatments for CRPS such as neuropathic pain medications and sympathetic blocks are often unsatisfactory for managing symptoms. The present cases highlight the use of a 60-day percutaneous peripheral nerve stimulation (PNS) treatment for three patients with CRPS Type I affecting the foot...
February 2024: Curēus
https://read.qxmd.com/read/38489226/combined-dexamethasone-and-dexmedetomidine-as-adjuncts-to-popliteal-and-saphenous-nerve-blocks-in-patients-undergoing-surgery-of-the-foot-or-ankle-a-randomized-blinded-placebo-controlled-clinical-trial
#8
JOURNAL ARTICLE
Mathias Maagaard, Kamilia S Funder, Nikolaj K Schou, Jeannette Ø Penny, Peter Toquer, Jens Laigaard, Emma R Stormholt, Anders K Nørskov, Pia Jæger, Jakob H Andersen, Ole Mathiesen
BACKGROUND: Both dexamethasone and dexmedetomidine increase the duration of analgesia of peripheral nerve blocks. The authors hypothesized that combined intravenous dexamethasone and intravenous dexmedetomidine would result in a greater duration of analgesia when compared with intravenous dexamethasone alone and placebo. METHODS: The authors randomly allocated participants undergoing surgery of the foot or ankle under general anesthesia and with a combined popliteal (sciatic) and saphenous nerve block to a combination of 12 mg dexamethasone and 1 mcg/kg dexmedetomidine, 12 mg dexamethasone, or placebo (saline)...
March 14, 2024: Anesthesiology
https://read.qxmd.com/read/38438218/comparison-of-the-popliteal-artery-and-the-capsule-of-the-posterior-knee-ipack-block-and-the-genicular-nerve-block-in-primary-total-knee-arthroplasty-a-prospective-randomized-trial
#9
JOURNAL ARTICLE
Abdulrahim Dündar, Deniz İpek, Mehmet Yalvaç, Şehmuz Kaya
OBJECTIVES: To compare the efficacy of genicular block and interspace between the popliteal artery and the posterior capsule (IPACK) block in the reduction of postoperative pain, the need for rescue analgesics, and the effects on a range of motion (ROM) in patients with TKA. METHODS: This prospective randomized controlled study was carried out between February and May 2023. Based on the block method, 60 participants were divided into three equal groups. These groups included the IPACK block group (n=20), the genicular block group (n=20), and control group (n=20)...
March 2024: Saudi Medical Journal
https://read.qxmd.com/read/38373818/plantar-compartment-block-for-hallux-valgus-surgery-a-proof-of-concept-anatomic-and-clinical-study
#10
JOURNAL ARTICLE
Matthias Herteleer, Olivier Choquet, Fabien Swisser, Nathalie Bernard, Audrey Gasc, François Canovas, Louis Dagneaux, Sophie Bringuier, Xavier Capdevila
BACKGROUND: Hallux valgus surgery is associated with moderate to severe postoperative pain. We hypothesized that a plantar compartment block may be a good technique for postoperative analgesia. We describe an anatomic approach to ultrasound-guided plantar compartment block and assess the clinical efficacy of the block for outpatient surgery. METHODS: The anatomic study was aimed to describe the plantar compartment, using both dissection methods and imaging, and to define a volume of local anesthetic...
February 19, 2024: Regional Anesthesia and Pain Medicine
https://read.qxmd.com/read/38340677/a-phase-3-active-controlled-trial-of-liposomal-bupivacaine-via-sciatic-nerve-block-in-the-popliteal-fossa-after-bunionectomy
#11
JOURNAL ARTICLE
Gary Schwartz, Jeffrey C Gadsden, Jeffrey Gonzales, Jacob Hutchins, Jia Song, O'Dane Brady, Mary DiGiorgi, Roy Winston
STUDY OBJECTIVE: To investigate the efficacy, safety, pharmacodynamics, and pharmacokinetics of liposomal bupivacaine (LB) administered via ultrasound-guided sciatic nerve block in the popliteal fossa in participants undergoing bunionectomy. DESIGN: Two-part, randomized, double-blind, active-controlled trial (NCT05157841). SETTING: Operating room, postanesthesia care unit, and health care facility (6 sites). PATIENTS: Adults with American Society of Anesthesiologists physical status classification ≤3 and body mass index ≥18 to <40 kg/m2 undergoing elective distal metaphyseal osteotomy...
February 9, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38316570/analgesic-effectiveness-of-continuous-versus-single-injection-adductor-canal-block-in-addition-to-continuous-popliteal-sciatic-nerve-block-for-bimalleolar-and-trimalleolar-ankle-fracture-surgery-prospective-randomized-controlled-trial
#12
JOURNAL ARTICLE
Young Uk Park, Han Bum Joe, Jong Wha Lee, Young Wook Seo
BACKGROUND: The adductor canal block is a well-known procedure for controlling postoperative pain after medial malleolus fracture surgery. Continuous nerve block is a viable option for blocking pain for a longer period although the literature on this subject is scarce. Therefore, this study aimed to compare continuous adductor canal block (cACB) group to single-injection adductor canal block (sACB) group in those with bimalleolar or trimalleolar ankle fractures. The procedure was performed in addition to a continuous sciatic nerve block for postoperative pain relief and patient satisfaction...
February 5, 2024: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://read.qxmd.com/read/38313966/comparative-efficacy-of-ipack-vs-popliteal-sciatic-nerve-block-for-pain-management-following-total-knee-arthroplasty-a-retrospective-analysis
#13
JOURNAL ARTICLE
Francisco Teixeira, Cristina P Sousa, Ana Patrícia Martins Pereira, Delilah Gonçalves, José C Sampaio, Miguel Sá
Introduction Total knee arthroplasty (TKA) is associated with severe acute postoperative pain. The use of tourniquets and drains (T/D) is common in TKA but may have an influence on postoperative pain and muscular strength. The infiltration of local anesthetic between the popliteal artery and capsule of the knee (iPACK block) is a motor-sparing block that provides analgesia to the posterior aspect of the knee. However, evidence regarding its efficacy is scarce. This study aims to assess the effectiveness of iPACK block and the impact of T/D use on pain and muscular strength after TKA...
January 2024: Curēus
https://read.qxmd.com/read/38268500/ccl19-positive-lymph-node-stromal-cells-govern-the-onset-of-inflammatory-arthritis-via-tropomyosin-receptor-kinase
#14
JOURNAL ARTICLE
Fabian Schälter, Vugar Azizov, Michael Frech, Kerstin Dürholz, Eva Schmid, Anna Hendel, Ilann Sarfati, Yuichi Maeda, Maria Sokolova, Ippei Miyagawa, Kristin Focke, Kerstin Sarter, Lisa G M van Baarsen, Stefan Krautwald, Georg Schett, Mario M Zaiss
OBJECTIVES: To assess the role of CCL19+ lymph node stromal cells of the joint draining popliteal lymph node (pLN) for the development of arthritis. METHODS: CCL19+ lymph node stromal cells were spatiotemporally depleted for 5 days in the pLN before the onset of collagen-induced arthritis (CIA) using Ccl19-Cre x iDTR mice. In addition, therapeutic treatment with recombinant CCL19-IgG, locally injected in the footpad, was used to confirm the results. RNA sequencing of lymph node stromal cells combined with T cell co-culture assays using tropomyosin receptor kinase (Trk) family inhibitors together with in vivo local pLN siRNA treatments were used to elucidate the pathway by which CCL19+ lymph node stromal cells initiate the onset of arthritis...
January 25, 2024: Arthritis & Rheumatology
https://read.qxmd.com/read/38235397/combined-single-shot-infiltration-between-the-popliteal-artery-and-capsule-of-the-knee-and-adductor-canal-block-with-bupivacaine-dexmedetomidine-and-dexamethasone-for-total-knee-arthroplasty-a-propensity-matched-analysis
#15
JOURNAL ARTICLE
Melina Shoni, Aneesh V Samineni, Seroos Salavati, Nikhil Mikkilineni, Allen Wang, Ayesha Abdeen, David Freccero
BACKGROUND: To investigate if combined single-shot adductor canal blockade (ACB) and infiltration between the popliteal artery and capsule of the knee (IPACK) provide better postoperative pain management compared to ACB alone for patients undergoing unilateral total knee arthroplasty (TKA). METHODS: This retrospective cohort study included adult patients who underwent primary, unilateral TKA. Patients were separated into 2 cohorts: single-shot ACB alone (performed with bupivacaine 0...
February 2024: Arthroplasty Today
https://read.qxmd.com/read/38190339/what-is-the-role-of-a-periarticular-injection-for-knee-arthroplasty-patients-receiving-a-multimodal-analgesia-regimen-incorporating-adductor-canal-and-infiltration-between-the-popliteal-artery-and-capsule-of-the-knee-blocks-a-randomized-blinded-placebo-controlled
#16
JOURNAL ARTICLE
Jacques T YaDeau, Fred D Cushner, Geoffrey Westrich, Justas Lauzadis, Richard L Kahn, Yi Lin, Enrique A Goytizolo, David J Mayman, Kethy M Jules-Elysee, Ejiro Gbaje, Douglas E Padgett
BACKGROUND: Optimal analgesic protocols for total knee arthroplasty (TKA) patients remain controversial. Multimodal analgesia is advocated, often including peripheral nerve blocks and/or periarticular injections (PAIs). If 2 blocks (adductor canal block [ACB] plus infiltration between the popliteal artery and capsule of the knee [IPACK]) are used, also performing PAI may not be necessary. This noninferiority trial hypothesized that TKA patients with ACB + IPACK + saline PAI (sham infiltration) would have pain scores that were no worse than those of patients with ACB + IPACK + active PAI with local anesthetic...
January 8, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38187980/evaluation-of-age-based-local-anaesthetic-dosing-of-bupivacaine-for-popliteal-sciatic-nerve-block-in-children-undergoing-foot-and-ankle-surgery-a-prospective-single-arm-interventional-study
#17
JOURNAL ARTICLE
Srinivasan Parthasarathy, T Kumar Venkatesh, Balachandar Saravanan
BACKGROUND AND AIMS: Recommendations on paediatric single-injection local anaesthetic (LA) dosing for peripheral nerve blocks (PNBs) are based on the children's weight and limited by weight-based toxicity concerns. In this study, we assessed the extent of circumferential spread and block characteristics following the injection of an age-based volume (age in years = LA volume) of 0.25% bupivacaine following popliteal sciatic nerve block (PSNB). METHODS: Thirty children aged between 2 and 12 years with the American Society of Anesthesiologists (ASA) physical status I and II and undergoing foot and ankle surgical procedures were given single-injection ultrasound-guided subparaneural PSNB using 0...
November 2023: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38002702/pain-management-functional-recovery-and-stress-response-expressed-by-nlr-and-plr-after-the-ipack-block-combined-with-adductor-canal-block-for-total-knee-arthroplasty-a-prospective-randomised-double-blinded-clinical-trial
#18
JOURNAL ARTICLE
Malgorzata Domagalska, Tomasz Reysner, Grzegorz Kowalski, Przemysław Daroszewski, Aleksander Mularski, Katarzyna Wieczorowska-Tobis
INTRODUCTION: This study aimed to investigate pain management, functional recovery, and stress response expressed by the neutrophile-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) after the popliteal artery and posterior knee capsule infiltration (iPACK) block combined with adductor canal block (ACB) in total knee arthroplasty (TKA). PATIENTS AND METHODS: This was a prospective, double-blinded, randomised, controlled trial in a tertiary referral hospital...
November 14, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37972929/duration-of-analgesia-after-forefoot-surgery-compared-between-an-ankle-and-a-sciatic-nerve-block-at-the-popliteal-crease-a-randomised-controlled-single-blinded-trial
#19
RANDOMIZED CONTROLLED TRIAL
Magnus Olofsson, Alexandre Nguyen, Jean-Benoit Rossel, Eric Albrecht
BACKGROUND: Forefoot surgery is associated with severe postoperative pain. Ankle and sciatic nerve blocks provide satisfactory postoperative analgesia after forefoot surgery, but little is known on their respective duration of analgesia. OBJECTIVE: This randomised controlled, single-blinded trial tested the hypothesis that after forefoot surgery in the setting of multimodal analgesia, an ankle block provides analgesia superior to that of a sciatic nerve block at the popliteal crease...
January 1, 2024: European Journal of Anaesthesiology
https://read.qxmd.com/read/37926063/distal-subsartorial-compartment-block-of-the-saphenous-nerve-a-dissection-study-and-a-patient-case-series
#20
JOURNAL ARTICLE
Anne E Jensen, Siska Bjørn, Thomas D Nielsen, Bernhard Moriggl, Romed Hoermann, Michael Vaeggemose, Thomas F Bendtsen
STUDY OBJECTIVE: A saphenous nerve block is an important tool for analgesia after foot and ankle surgery. The conventional midthigh approach to saphenous nerve block in the femoral triangle may impede ambulation by impairing quadriceps motor function. PRIMARY OBJECTIVE: Developing a selective saphenous nerve block targeting the nerve distal to its emergence from the adductor canal in the subsartorial compartment. DESIGN: This study consists of A) a dissection study and B) Data from a clinical case series...
February 2024: Journal of Clinical Anesthesia
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