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https://www.readbyqxmd.com/read/29353397/patients-perceptions-of-pharmacist-managed-diabetes-services-in-the-ambulatory-care-and-community-settings-within-singapore
#1
Melanie Yee Lee Siaw, Jing Heng Toh, Joyce Yu-Chia Lee
Background Qualitative evidence on patients' perceptions of pharmacist-managed diabetes services (PMDSs) is limited. Objective To explore patients' perceptions of PMDSs Setting Patients being cared for in the outpatient settings in Singapore. Methods This focus group included patients who were diagnosed with type 2 diabetes, spoke either English or Mandarin, attended PMDSs for at least 6 months in the ambulatory care or community settings, and were at least 21 years of age. Patients with cognitive impairments or mobility issues were excluded...
January 20, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29353395/comparison-of-osteoporosis-in-us-adults-with-type-1-and-type-2-diabetes-mellitus
#2
S C DeShields, T D Cunningham
PURPOSE: We examined bone mineral density (BMD) and osteoporosis prevalence in those with type 1 compared to type 2 diabetes derived from a nationally representative sample from the civilian community in the United States. METHODS: Data from the National Health and Nutrition Examination Survey (NHANES) for 2005-2006, 2007-2008, 2009-2010, and 2013-2014 were merged to obtain a large sample of diabetics at least 20 years of age with participation in the interview and medical examination...
January 20, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29353369/mental-health-professionals-attitudes-towards-mental-illness-professional-and-cultural-factors-in-the-inter-nos-study
#3
Francisco Del Olmo-Romero, María González-Blanco, Salvador Sarró, Jaime Grácio, Manuel Martín-Carrasco, Ana C Martinez-Cabezón, Giampaolo Perna, Edith Pomarol-Clotet, Pedro Varandas, Javier Ballesteros-Rodríguez, Carlos Rebolleda-Gil, Giovanna Vanni, Eduardo González-Fraile
BACKGROUND: Research shows that personnel working in mental health facilities may share some of the societal prejudices towards mental illness. This might result in stigmatizing behaviours towards people suffering from mental disorders, undermining the quality of their care. AIMS: To describe and compare attitudes towards mental illness across a sample of professionals working in a wide range of mental health facilities in Spain, Portugal and Italy. METHOD: We administered a survey to personnel including two questionnaires related to stigmatizing attitudes: The Community Attitudes toward the Mentally Ill (CAMI) and the Attribution Questionnaire (AQ-27)...
January 20, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29353339/chronic-pain-discomfort-quality-of-life-and-impact-on-sex-life-after-open-inguinal-hernia-mesh-repair-an-expertise-based-randomized-clinical-trial-comparing-lightweight-and-heavyweight-mesh
#4
M Rutegård, R Gümüsçü, G Stylianidis, P Nordin, E Nilsson, M M Haapamäki
PURPOSE: There is a paucity of high-quality evidence concerning mesh choice in open inguinal hernia repair. Using an expertise-based randomized clinical trial design, we aimed to evaluate the postoperative impact of two different mesh types on pain and discomfort, quality of life and sex life. METHODS: In two regional hospitals, male patients with primary inguinal hernia were randomized to one of two groups of surgeons that performed the Lichtenstein operation. One group of surgeons used a heavyweight polypropylene mesh (90 g/m2, Bard™ Flatmesh, Davol) while the second group employed a lightweight mesh (28 g/m2, ULTRAPRO™, Ethicon)...
January 20, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29353338/the-use-of-infant-confinement-equipment-in-community-based-child-care-centers-an-analysis-of-centers-participating-in-a-statewide-quality-rating-and-improvement-system
#5
Rena A Hallam, Kaitlin Bargreen, Hillary N Fouts, Laura Lessard, Christine Skrobot
Objectives Although infants increasingly spend time in community-based child care centers, little attention has been paid to their physical activity experiences while in group care. In particular, the use of devices to restrict infant mobility, such as bouncy seats, high chairs, cribs, and stationary activity centers, has received little attention in the physical activity literature. The current study examines the presence and use of these confinement devices in infant classrooms. Methods A secondary analysis of observational data in child care centers participating in Delaware's Quality Rating and Improvement System was conducted...
January 20, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29353257/ethical-dilemmas-of-recording-and-reviewing-neonatal-resuscitation
#6
REVIEW
Maria C den Boer, Mirjam Houtlosser, Henriëtte Anje van Zanten, Elizabeth E Foglia, Dirk P Engberts, Arjan B Te Pas
Neonatal resuscitation is provided to approximately 3% of neonates. Adequate ventilation is often the key to successful resuscitation, but this can be difficult to provide. There is increasing evidence that inappropriate respiratory support can have severe consequences. Several neonatal intensive care units have recorded and reviewed neonatal resuscitation procedures for quality assessment, education and research; however, ethical dilemmas sometimes make it difficult to implement this review process. We reviewed the literature on the development of recording and reviewing neonatal resuscitation and have summarised the ethical concerns involved...
January 20, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29353183/automatic-bad-channel-detection-in-intracranial-electroencephalographic-recordings-using-ensemble-machine-learning
#7
Viateur Tuyisenge, Lena Trebaul, Manik Bhattacharjee, Blandine Chanteloup-Forêt, Carole Saubat-Guigui, Ioana Mîndruţă, Sylvain Rheims, Louis Maillard, Philippe Kahane, Delphine Taussig, Olivier David
OBJECTIVE: Intracranial electroencephalographic (iEEG) recordings contain "bad channels", which show non-neuronal signals. Here, we developed a new method that automatically detects iEEG bad channels using machine learning of seven signal features. METHODS: The features quantified signals' variance, spatial-temporal correlation and nonlinear properties. Because the number of bad channels is usually much lower than the number of good channels, we implemented an ensemble bagging classifier known to be optimal in terms of stability and predictive accuracy for datasets with imbalanced class distributions...
December 24, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29353164/a-phase-ii-study-of-nab-paclitaxel-in-combination-with-ramucirumab-in-patients-with-previously-treated-advanced-gastric-cancer
#8
Hideaki Bando, Hideki Shimodaira, Kazumasa Fujitani, Atsuo Takashima, Kensei Yamaguchi, Norisuke Nakayama, Takehiro Takahashi, Eiji Oki, Mizutomo Azuma, Tomohiro Nishina, Shuichi Hironaka, Yoshito Komatsu, Kohei Shitara
BACKGROUND: Nanoparticle albumin-bound (nab)-paclitaxel was developed to improve paclitaxel solubility and does not need premedication to avoid infusion-related reactions associated with solvent-based (sb)-paclitaxel. We conducted a phase II trial to investigate the efficacy and safety of nab-paclitaxel plus ramucirumab combination therapy for previously treated advanced gastric cancer. PATIENTS AND METHODS: Patients with unresectable advanced gastric cancer refractory to first-line chemotherapy were administered nab-paclitaxel 100 mg/m2 intravenously on days 1, 8 and 15, plus ramucirumab 8 mg/kg intravenously on days 1 and 15 of a 28-day cycle...
January 17, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29353103/taking-the-heat-or-taking-the-temperature-a-qualitative-study-of-a-large-scale-exercise-in-seeking-to-measure-for-improvement-not-blame
#9
Natalie Armstrong, Liz Brewster, Carolyn Tarrant, Ruth Dixon, Janet Willars, Maxine Power, Mary Dixon-Woods
Measurement of quality and safety has an important role in improving healthcare, but is susceptible to unintended consequences. One frequently made argument is that optimising the benefits from measurement requires controlling the risks of blame, but whether it is possible to do this remains unclear. We examined responses to a programme known as the NHS Safety Thermometer (NHS-ST). Measuring four common patient harms in diverse care settings with the goal of supporting local improvement, the programme explicitly eschews a role for blame...
January 2, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29353098/the-anti-inflammatory-effects-of-statins-on-patients-with-rheumatoid-arthritis-a-systemic-review-and-meta-analysis-of-15-randomized-controlled-trials
#10
REVIEW
Guo-Min Li, Jie Zhao, Bing Li, Xiao-Fei Zhang, Jian-Xiong Ma, Xin-Long Ma, Jun Liu
BACKGROUND: Over the past several years, numerous studies investigated the anti-inflammatory effects of statin on patients with RA. However, the findings of the individual studies were often inconsistent or conflicting. MATERIALS AND METHODS: The Pubmed, Web of Science, Embase, Cochrane Library and CNKI literature databases were searched in order to identify randomized controlled clinical trials where the association between the anti-inflammatory effect of statin and RA was investigated...
January 15, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29353088/healthcare-students-evaluation-of-the-clinical-learning-environment-and-supervision-a-cross-sectional-study
#11
Salla Pitkänen, Maria Kääriäinen, Ashlee Oikarainen, Anna-Maria Tuomikoski, Satu Elo, Heidi Ruotsalainen, Mikko Saarikoski, Taina Kärsämänoja, Kristina Mikkonen
BACKGROUND: The purpose of clinical placements and supervision is to promote the development of healthcare students´ professional skills. High-quality clinical learning environments and supervision were shown to have significant influence on healthcare students´ professional development. OBJECTIVES: This study aimed to describe healthcare students` evaluation of the clinical learning environment and supervision, and to identify the factors that affect these. DESIGN: The study was performed as a cross-sectional study...
January 17, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29353010/modulation-of-immune-responses-by-plasmodium-falciparum-infection-in-asymptomatic-children-living-in-the-endemic-region-of-mbita-western-kenya
#12
Caroline Kijogi, Daisuke Kimura, Lam Quoc Bao, Risa Nakamura, Evans Asena Chadeka, Ngetich Benard Cheruiyot, Felix Bahati, Kazuhide Yahata, Osamu Kaneko, Sammy M Njenga, Yoshio Ichinose, Shinjiro Hamano, Katsuyuki Yui
Individuals living in malaria endemic areas become clinically immune after multiple re-infections over time and remain infected without apparent symptoms. However, it is unclear why a long period is required to gain clinical immunity to malaria, and how such immunity is maintained. Although malaria infection is reported to induce inhibition of immune responses, studies on asymptomatic individuals living in endemic regions of malaria are relatively scarce. We conducted a cross-sectional study of immune responses in asymptomatic school children aged 4-16years living in an area where Plasmodium falciparum and Schistosoma mansoni infections are co-endemic in Kenya...
January 15, 2018: Parasitology International
https://www.readbyqxmd.com/read/29352986/association-of-androgen-deprivation-therapy-and-thromboembolic-events-a-systematic-review-and-meta-analysis
#13
Kevin T Nead, Ninjin Boldbaatar, David D Yang, Sumi Sinha, Paul L Nguyen
OBJECTIVES: To investigate the association of androgen deprivation therapy (ADT) for prostate cancer with thromboembolic events. METHODS: PubMed, Web of Science, and Scopus were queried April 5, 2017 for systematic review. Additionally, The World Health Organization International Trials Registry Platform was queried June 23rd, 2017. Eligible studies reported thromboembolic events among individuals with prostate cancer exposed to ADT versus a lesser-exposed group...
January 15, 2018: Urology
https://www.readbyqxmd.com/read/29352973/the-senegal-urban-reproductive-health-initiative-a-longitudinal-program-impact-evaluation
#14
Aimee Benson, Lisa Calhoun, Meghan Corroon, Abdou Gueye, David Guilkey, Essete Kebede, Peter Lance, Rick O'Hara, Ilene S Speizer, John Stewart, Jennifer Winston
OBJECTIVES: This paper presents the impact of key components of the Senegal Urban Reproductive Health Initiative, including radio, television, community-based activities, Muslim religious-leader engagement and service quality improvement on modern contraceptive use by all women and the sub-sample of poor women. STUDY DESIGN: This study uses baseline (2011) and endline (2015) longitudinal data from a representative sample of urban women first surveyed in 2011 to examine the impact of the Initiative's demand- and supply-side activities on modern contraceptive use...
January 15, 2018: Contraception
https://www.readbyqxmd.com/read/29352818/validity-and-reliability-of-the-palliative-care-transition-measure-for-caregivers-pctm-c
#15
Daniela D'Angelo, Chiara Mastroianni, Marco Artico, Valentina Biagioli, Roberto Latina, Michela Guarda, Michela Piredda, Maria Grazia De Marinis
OBJECTIVE: Patients suffering from advanced disease face different care transitions. The transition from acute to palliative care is challenging and may lead to the discontinuity of care. Family caregivers become important sources of information, as patients begin to experience difficulties in coping with emotional transition events. The Care Transition Measure was developed to evaluate care transitions as experienced by the elderly. It has never been used in palliative care. The aim of this study was to test the validity and reliability of a modified version of the Palliative Care Transition Measure, specifically the Palliative Care Transition Measure for Caregivers (PCTM-C)...
January 21, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29352663/early-versus-delayed-closure-of-bladder-exstrophy-a-national-surgical-quality-improvement-program-pediatric-analysis
#16
J J Ahn, M Shnorhavorian, C Katz, A B Goldin, P A Merguerian
INTRODUCTION: Delayed closure of bladder exstrophy has become more popular; however, there is limited the evidence of its success. Existing literature focuses on intermediate and long-term outcomes, and short-term postoperative outcomes are limited by the small number of cases and varying follow-up methods. OBJECTIVE: The objectives of the current study were to: 1) compare 30-day complications after early and delayed closure of bladder exstrophy, and 2) evaluate practice patterns of bladder exstrophy closure...
December 15, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29352641/can-you-do-health-disparities-research-with-publicly-available-datasets
#17
Danny R Hughes
RATIONALE AND OBJECTIVES: Given the growing importance of identifying and reducing health disparities, it is important for radiologist researchers to engage in this space to promote evidence-based imaging disparities policy. However, researchers are often hindered by access to appropriate data to perform quality research. MATERIALS AND METHODS: This paper reviews existing publicly available data sets that may be useful for performing imaging disparities research...
January 15, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29352637/the-ability-of-topical-and-systemic-statins-to-increase-osteogenesis-around-dental-implants-a-systematic-review-of-histomorphometric-outcomes-in-animal-studies
#18
REVIEW
V Moraschini, D C F Almeida, J A Calasans-Maia, M Diuana Calasans-Maia
The purpose of this systematic review was to evaluate the quantitative histomorphometric outcomes of animal studies investigating statins as a pro-osteogenic agent to enhance the osseointegration of dental implants. Some animal studies have suggested a beneficial action of statins on bone tissue. Electronic and manual literature searches, without date or language restriction, ​​were performed by two independent review authors up to February 2017. Eligibility criteria included animal trials quantitatively analysing the pro-osteogenic effect of statins on dental implants...
January 15, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29352616/assessing-advanced-airway-management-performance-in-a-national-cohort-of-emergency-medical-services-agencies
#19
Henry E Wang, John P Donnelly, Dustin Barton, Jeffrey L Jarvis
STUDY OBJECTIVE: Although often the focus of quality improvement efforts, emergency medical services (EMS) advanced airway management performance has few national comparisons, nor are there many assessments with benchmarks accounting for differences in agency volume or patient mix. We seek to assess variations in advanced airway management and conventional intubation performance in a national cohort of EMS agencies. METHODS: We used EMS data from ESO Solutions, a national EMS electronic health record system...
January 15, 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29352609/induction-of-mitophagy-in-the-hei-oc1-auditory-cell-line-and-activation-of-the-atg12-lc3-pathway-in-the-organ-of-corti
#20
Cristian Setz, Anne-Sophie Benischke, Anna Catharina Pinho Ferreira Bento, Yves Brand, Soledad Levano, Franziska Paech, Katharina Leitmeyer, Daniel Bodmer
Autophagy is a highly evolutionary conserved quality control defense mechanism within cells, which has also been implicated in cell death processes. In the mammalian inner ear, autophagy has been shown to play a role during early morphogenesis as well as in adult cochlear hair cells exposed to ototoxic insults. Mitophagy, a selective autophagic cell process targeting mitochondria, hasn't been studied in the inner ear so far. On this work, we searched for molecular indicators of mitophagy within House Ear Institute-Organ of Corti-1 (HEI-OC1) cells as well as in the organ of Corti (OC)...
January 11, 2018: Hearing Research
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